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PLoS Biol
    March 2024
  1. BEKDASH R, Yoshida K, Nair MS, Qiu L, et al
    Developing inhibitory peptides against SARS-CoV-2 envelope protein.
    PLoS Biol. 2024;22:e3002522.
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    January 2024
  2. RUSSELL TW, Townsley H, Abbott S, Hellewell J, et al
    Combined analyses of within-host SARS-CoV-2 viral kinetics and information on past exposures to the virus in a human cohort identifies intrinsic differences of Omicron and Delta variants.
    PLoS Biol. 2024;22:e3002463.
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    December 2023
  3. SIMMONS HC, Watanabe A, Oguin Iii TH, Van Itallie ES, et al
    A new class of antibodies that overcomes a steric barrier to cross-group neutralization of influenza viruses.
    PLoS Biol. 2023;21:e3002415.
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    November 2023
  4. VALE-COSTA S, Etibor TA, Bras D, Sousa AL, et al
    ATG9A regulates the dissociation of recycling endosomes from microtubules to form liquid influenza A virus inclusions.
    PLoS Biol. 2023;21:e3002290.
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  5. ZHU Z, Fan H, Fodor E
    Defining the minimal components of the influenza A virus replication machinery via an in vitro reconstitution system.
    PLoS Biol. 2023;21:e3002370.
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    Minding the "T"s beyond the "B"s: Shaping vaccines for future pandemics.
    PLoS Biol. 2023;21:e3002351.
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  7. LYTRAS S, Wickenhagen A, Sugrue E, Stewart DG, et al
    Resurrection of 2'-5'-oligoadenylate synthetase 1 (OAS1) from the ancestor of modern horseshoe bats blocks SARS-CoV-2 replication.
    PLoS Biol. 2023;21:e3002398.
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    August 2023
  8. LADNER JT, Sahl JW
    Towards a post-pandemic future for global pathogen genome sequencing.
    PLoS Biol. 2023;21:e3002225.
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  9. LOBINSKA G, Pilpel Y, Nowak MA
    Evolutionary safety of lethal mutagenesis driven by antiviral treatment.
    PLoS Biol. 2023;21:e3002214.
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  10. KRAFT TS, Seabright E, Alami S, Jenness SM, et al
    Metapopulation dynamics of SARS-CoV-2 transmission in a small-scale Amazonian society.
    PLoS Biol. 2023;21:e3002108.
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    July 2023
  11. OLAJIDE OM, Osman MK, Robert J, Kessler S, et al
    Evolutionarily conserved amino acids in MHC-II mediate bat influenza A virus entry into human cells.
    PLoS Biol. 2023;21:e3002182.
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    June 2023
  12. STRINE MS, Cai WL, Wei J, Alfajaro MM, et al
    DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner.
    PLoS Biol. 2023;21:e3002097.
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  13. CHEN NFG, Chaguza C, Gagne L, Doucette M, et al
    Development of an amplicon-based sequencing approach in response to the global emergence of mpox.
    PLoS Biol. 2023;21:e3002151.
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  14. TSU BV, Agarwal R, Gokhale NS, Kulsuptrakul J, et al
    Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome.
    PLoS Biol. 2023;21:e3002144.
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    May 2023
  15. EALES O, Haw D, Wang H, Atchison C, et al
    Dynamics of SARS-CoV-2 infection hospitalisation and infection fatality ratios over 23 months in England.
    PLoS Biol. 2023;21:e3002118.
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    February 2023
  16. SIMS A, Tornaletti LB, Jasim S, Pirillo C, et al
    Superinfection exclusion creates spatially distinct influenza virus populations.
    PLoS Biol. 2023;21:e3001941.
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  17. SHILTS J, Crozier TWM, Teixeira-Silva A, Gabaev I, et al
    LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein.
    PLoS Biol. 2023;21:e3001959.
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  18. LOO L, Waller MA, Moreno CL, Cole AJ, et al
    Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs.
    PLoS Biol. 2023;21:e3001967.
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    Improve how science advice is provided to governments by learning from "experts in expert advice".
    PLoS Biol. 2023;21:e3002004.
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  20. TANG AT, Buchholz DW, Szigety KM, Imbiakha B, et al
    Cell-autonomous requirement for ACE2 across organs in lethal mouse SARS-CoV-2 infection.
    PLoS Biol. 2023;21:e3001989.
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    December 2022
  21. BAKER SF, Meistermann H, Tzouros M, Baker A, et al
    Alternative splicing liberates a cryptic cytoplasmic isoform of mitochondrial MECR that antagonizes influenza virus.
    PLoS Biol. 2022;20:e3001934.
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    November 2022
  22. MESCI P, de Souza JS, Martin-Sancho L, Macia A, et al
    SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir.
    PLoS Biol. 2022;20:e3001845.
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  23. GARCIA G JR, Jeyachandran AV, Wang Y, Irudayam JI, et al
    Hippo signaling pathway activation during SARS-CoV-2 infection contributes to host antiviral response.
    PLoS Biol. 2022;20:e3001851.
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  24. NIEMEYER D, Stenzel S, Veith T, Schroeder S, et al
    SARS-CoV-2 variant Alpha has a spike-dependent replication advantage over the ancestral B.1 strain in human cells with low ACE2 expression.
    PLoS Biol. 2022;20:e3001871.
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    October 2022
  25. SONG J, Chow RD, Pena-Hernandez MA, Zhang L, et al
    LRRC15 inhibits SARS-CoV-2 cellular entry in trans.
    PLoS Biol. 2022;20:e3001805.
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    September 2022
  26. DAY T, Kennedy DA, Read AF, Gandon S, et al
    Pathogen evolution during vaccination campaigns.
    PLoS Biol. 2022;20:e3001804.
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  27. CHING KL, de Vries M, Gago J, Dancel-Manning K, et al
    ACE2-containing defensosomes serve as decoys to inhibit SARS-CoV-2 infection.
    PLoS Biol. 2022;20:e3001754.
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  28. FERNBACH S, Hale BG
    SARS-CoV-2 takes the bait: Exosomes as endogenous decoys.
    PLoS Biol. 2022;20:e3001787.
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    August 2022
  29. LIU H, Riggi M, Rogers J, Meyer M, et al
    A new tool for annotating scientific animations and supporting scientific dialogue.
    PLoS Biol. 2022;20:e3001731.
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  30. ZHU Y, Chew KY, Wu M, Karawita AC, et al
    Ancestral SARS-CoV-2, but not Omicron, replicates less efficiently in primary pediatric nasal epithelial cells.
    PLoS Biol. 2022;20:e3001728.
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    July 2022
  31. BUSNADIEGO I, Abela IA, Frey PM, Hofmaenner DA, et al
    Critically ill COVID-19 patients with neutralizing autoantibodies against type I interferons have increased risk of herpesvirus disease.
    PLoS Biol. 2022;20:e3001709.
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  32. ROELLE SM, Shukla N, Pham AT, Bruchez AM, et al
    Expanded ACE2 dependencies of diverse SARS-like coronavirus receptor binding domains.
    PLoS Biol. 2022;20:e3001738.
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    June 2022
    Why does viral RNA sometimes persist after recovery from acute infections?
    PLoS Biol. 2022;20:e3001687.
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  34. TAUBE JC, Miller PB, Drake JM
    An open-access database of infectious disease transmission trees to explore superspreader epidemiology.
    PLoS Biol. 2022;20:e3001685.
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    May 2022
  35. ZHU DY, Gorman MJ, Yuan D, Yu J, et al
    Defining the determinants of protection against SARS-CoV-2 infection and viral control in a dose-down Ad26.CoV2.S vaccine study in nonhuman primates.
    PLoS Biol. 2022;20:e3001609.
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  36. LU-CULLIGAN A, Tabachnikova A, Perez-Then E, Tokuyama M, et al
    No evidence of fetal defects or anti-syncytin-1 antibody induction following COVID-19 mRNA vaccination.
    PLoS Biol. 2022;20:e3001506.
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  37. SYENINA A, Gan ES, Toh JZN, de Alwis R, et al
    Adverse effects following anti-COVID-19 vaccination with mRNA-based BNT162b2 are alleviated by altering the route of administration and correlate with baseline enrichment of T and NK cell genes.
    PLoS Biol. 2022;20:e3001643.
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  38. RICE BL, Lessler J, McKee C, Metcalf CJE, et al
    Why do some coronaviruses become pandemic threats when others do not?
    PLoS Biol. 2022;20:e3001652.
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  39. FOLARIN RO, Maina MB, Akinbo AK, Runsewe-Abiodun TI, et al
    Bypassing shortages of personal protective equipment in low-income settings using local production and open source tools.
    PLoS Biol. 2022;20:e3001658.
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    March 2022
  40. BESANCON L, Bik E, Heathers J, Meyerowitz-Katz G, et al
    Correction of scientific literature: Too little, too late!
    PLoS Biol. 2022;20:e3001572.
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  41. JANG KK, Kaczmarek ME, Dallari S, Chen YH, et al
    Variable susceptibility of intestinal organoid-derived monolayers to SARS-CoV-2 infection.
    PLoS Biol. 2022;20:e3001592.
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    February 2022
  42. FINCH E, Lowe R, Fischinger S, de St Aubin M, et al
    SARS-CoV-2 antibodies protect against reinfection for at least 6 months in a multicentre seroepidemiological workplace cohort.
    PLoS Biol. 2022;20:e3001531.
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  43. BRIERLEY L, Nanni F, Polka JK, Dey G, et al
    Tracking changes between preprint posting and journal publication during a pandemic.
    PLoS Biol. 2022;20:e3001285.
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    December 2021
  44. AMANAT F, Strohmeier S, Meade P, Dambrauskas N, et al
    Vaccination with SARS-CoV-2 variants of concern protects mice from challenge with wild-type virus.
    PLoS Biol. 2021;19:e3001384.
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  45. CASTIGLIONE GM, Zhou L, Xu Z, Neiman Z, et al
    Evolutionary pathways to SARS-CoV-2 resistance are opened and closed by epistasis acting on ACE2.
    PLoS Biol. 2021;19:e3001510.
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  46. HERDER V, Dee K, Wojtus JK, Epifano I, et al
    Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defenses.
    PLoS Biol. 2021;19:e3001065.
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    November 2021
  47. MURUATO A, Vu MN, Johnson BA, Davis-Gardner ME, et al
    Mouse-adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge.
    PLoS Biol. 2021;19:e3001284.
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    October 2021
    Wildlife must be protected from crime and trade for the sake of public and planetary health.
    PLoS Biol. 2021;19:e3001422.
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  49. JACK A, Ferro LS, Trnka MJ, Wehri E, et al
    SARS-CoV-2 nucleocapsid protein forms condensates with viral genomic RNA.
    PLoS Biol. 2021;19:e3001425.
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    September 2021
  50. MOLLENTZE N, Babayan SA, Streicker DG
    Identifying and prioritizing potential human-infecting viruses from their genome sequences.
    PLoS Biol. 2021;19:e3001390.
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    August 2021
  51. WANG SY, Takahashi T, Pine AB, Damsky WE, et al
    Challenges in interpreting cytokine data in COVID-19 affect patient care and management.
    PLoS Biol. 2021;19:e3001373.
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    July 2021
  52. KISSLER SM, Fauver JR, Mack C, Olesen SW, et al
    Viral dynamics of acute SARS-CoV-2 infection and applications to diagnostic and public health strategies.
    PLoS Biol. 2021;19:e3001333.
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  53. HOTEZ PJ
    Mounting antiscience aggression in the United States.
    PLoS Biol. 2021;19:e3001369.
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    June 2021
  54. HEFFRON AS, McIlwain SJ, Amjadi MF, Baker DA, et al
    The landscape of antibody binding in SARS-CoV-2 infection.
    PLoS Biol. 2021;19:e3001265.
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  55. NICHOLS JD, Bogich TL, Howerton E, Bjornstad ON, et al
    Strategic testing approaches for targeted disease monitoring can be used to inform pandemic decision-making.
    PLoS Biol. 2021;19:e3001307.
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    May 2021
  56. VOGELS CBF, Breban MI, Ott IM, Alpert T, et al
    Multiplex qPCR discriminates variants of concern to enhance global surveillance of SARS-CoV-2.
    PLoS Biol. 2021;19:e3001236.
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  57. FU D, Zhang G, Wang Y, Zhang Z, et al
    Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes.
    PLoS Biol. 2021;19:e3001209.
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  58. LOWE-POWER TM, Dyson L, Polter AM
    A generation of junior faculty is at risk from the impacts of COVID-19.
    PLoS Biol. 2021;19:e3001266.
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    April 2021
  59. MOGHADAS SM, Vilches TN, Zhang K, Nourbakhsh S, et al
    Evaluation of COVID-19 vaccination strategies with a delayed second dose.
    PLoS Biol. 2021;19:e3001211.
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  60. FRASER N, Brierley L, Dey G, Polka JK, et al
    The evolving role of preprints in the dissemination of COVID-19 research and their impact on the science communication landscape.
    PLoS Biol. 2021;19:e3000959.
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  61. GALLAGHER T, McCray PB Jr
    The first few days of a SARS-CoV-2 infection viewed at single-cell resolution.
    PLoS Biol. 2021;19:e3001217.
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  62. ZHU X, Mannar D, Srivastava SS, Berezuk AM, et al
    Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies.
    PLoS Biol. 2021;19:e3001237.
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  63. FERGUSON J, Dunn S, Best A, Mirza J, et al
    Validation testing to determine the sensitivity of lateral flow testing for asymptomatic SARS-CoV-2 detection in low prevalence settings: Testing frequency and public health messaging is key.
    PLoS Biol. 2021;19:e3001216.
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    March 2021
    Racism, disease, and vaccine refusal: People of color are dying for access to COVID-19 vaccines.
    PLoS Biol. 2021;19:e3001167.
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  65. FULWEILER RW, Davies SW, Biddle JF, Burgin AJ, et al
    Rebuild the Academy: Supporting academic mothers during COVID-19 and beyond.
    PLoS Biol. 2021;19:e3001100.
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  66. KIM KS, Ejima K, Iwanami S, Fujita Y, et al
    A quantitative model used to compare within-host SARS-CoV-2, MERS-CoV, and SARS-CoV dynamics provides insights into the pathogenesis and treatment of SARS-CoV-2.
    PLoS Biol. 2021;19:e3001128.
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  67. MACLEAN OA, Lytras S, Weaver S, Singer JB, et al
    Natural selection in the evolution of SARS-CoV-2 in bats created a generalist virus and highly capable human pathogen.
    PLoS Biol. 2021;19:e3001115.
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  68. POHL MO, Busnadiego I, Kufner V, Glas I, et al
    SARS-CoV-2 variants reveal features critical for replication in primary human cells.
    PLoS Biol. 2021;19:e3001006.
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  69. RAVINDRA NG, Alfajaro MM, Gasque V, Huston NC, et al
    Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes.
    PLoS Biol. 2021;19:e3001143.
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    February 2021
  70. RIHN SJ, Merits A, Bakshi S, Turnbull ML, et al
    A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research.
    PLoS Biol. 2021;19:e3001091.
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  71. COMER SP, Cullivan S, Szklanna PB, Weiss L, et al
    COVID-19 induces a hyperactive phenotype in circulating platelets.
    PLoS Biol. 2021;19:e3001109.
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    January 2021
  72. HOTEZ PJ
    Anti-science kills: From Soviet embrace of pseudoscience to accelerated attacks on US biomedicine.
    PLoS Biol. 2021;19:e3001068.
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    December 2020
  73. KIM JI, Park S, Bae JY, Lee S, et al
    Glycosylation generates an efficacious and immunogenic vaccine against H7N9 influenza virus.
    PLoS Biol. 2020;18:e3001024.
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  74. REIJNS MAM, Thompson L, Acosta JC, Black HA, et al
    A sensitive and affordable multiplex RT-qPCR assay for SARS-CoV-2 detection.
    PLoS Biol. 2020;18:e3001030.
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    November 2020
  75. KENNEDY DA, Read AF
    Monitor for COVID-19 vaccine resistance evolution during clinical trials.
    PLoS Biol. 2020;18:e3001000.
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  76. ALTHOUSE BM, Wenger EA, Miller JC, Scarpino SV, et al
    Superspreading events in the transmission dynamics of SARS-CoV-2: Opportunities for interventions and control.
    PLoS Biol. 2020;18:e3000897.
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  77. ZHOU Y, Hou Y, Shen J, Mehra R, et al
    A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19.
    PLoS Biol. 2020;18:e3000970.
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  78. KADING RC, Kingston T
    Common ground: The foundation of interdisciplinary research on bat disease emergence.
    PLoS Biol. 2020;18:e3000947.
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    October 2020
  79. KUDO E, Israelow B, Vogels CBF, Lu P, et al
    Detection of SARS-CoV-2 RNA by multiplex RT-qPCR.
    PLoS Biol. 2020;18:e3000867.
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  80. BRUCE EA, Huang ML, Perchetti GA, Tighe S, et al
    Direct RT-qPCR detection of SARS-CoV-2 RNA from patient nasopharyngeal swabs without an RNA extraction step.
    PLoS Biol. 2020;18:e3000896.
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  81. KUCHARSKI AJ, Funk S, Eggo RM
    The COVID-19 response illustrates that traditional academic reward structures and metrics do not reflect crucial contributions to modern science.
    PLoS Biol. 2020;18:e3000913.
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    September 2020
  82. SELZER L, Su Z, Pintilie GD, Chiu W, et al
    Full-length three-dimensional structure of the influenza A virus M1 protein and its organization into a matrix layer.
    PLoS Biol. 2020;18:e3000827.
    >> Share

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