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Articles published in
Antiviral Res
    November 2021
  1. VANDERLINDEN E, Marchand A, Van Berwaer R, van Dam W, et al
    A broad influenza virus inhibitor acting via IMP dehydrogenase and in synergism with ribavirin.
    Antiviral Res. 2021 Nov 15:105208. doi: 10.1016/j.antiviral.2021.105208.
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    August 2021
  2. GARCIA-DORIVAL I, Cuesta-Geijo MA, Barrado-Gil L, Galindo I, et al
    Identification of Niemann-Pick C1 protein as a potential novel SARS-CoV-2 intracellular target.
    Antiviral Res. 2021 Aug 24:105167. doi: 10.1016/j.antiviral.2021.105167.
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  3. ESCAFFRE O, Freiberg AN
    Polyphenylene carboxymethylene (PPCM) microbicide repurposed as antiviral against SARS-CoV-2. Proof of concept in primary human undifferentiated epithelial cells.
    Antiviral Res. 2021 Aug 9:105162. doi: 10.1016/j.antiviral.2021.105162.
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  4. LEACH A, Ilca FT, Akbar Z, Ferrari M, et al
    A tetrameric ACE2 protein broadly neutralizes SARS-CoV-2 spike variants of concern with elevated potency.
    Antiviral Res. 2021 Aug 7:105147. doi: 10.1016/j.antiviral.2021.105147.
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  5. ISON MG, Hayden FG, Hay AJ, Gubareva LV, et al
    Influenza polymerase inhibitor resistance: Assessment of the current state of the art - A report of the isirv Antiviral group.
    Antiviral Res. 2021;194:105158.
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    July 2021
  6. KASPRZYK R, Spiewla TJ, Smietanski M, Golojuch S, et al
    Identification and evaluation of potential SARS-CoV-2 antiviral agents targeting mRNA cap guanine N7-Methyltransferase.
    Antiviral Res. 2021;193:105142.
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  7. TOURET F, Driouich JS, Cochin M, Petit PR, et al
    Preclinical evaluation of Imatinib does not support its use as an antiviral drug against SARS-CoV-2.
    Antiviral Res. 2021;193:105137.
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  8. GAN ES, Syenina A, Linster M, Ng B, et al
    A mouse model of lethal respiratory dysfunction for SARS-CoV-2 infection.
    Antiviral Res. 2021;193:105138.
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  9. PARK JH, Kim B, Antigua KJC, Jeong JH, et al
    Baloxavir-oseltamivir combination therapy inhibits the emergence of resistant substitutions in influenza A virus PA gene in a mouse model.
    Antiviral Res. 2021;193:105126.
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  10. PERSOONS L, Vanderlinden E, Vangeel L, Wang X, et al
    Broad spectrum anti-coronavirus activity of a series of anti-malaria quinoline analogues.
    Antiviral Res. 2021 Jul 1:105127. doi: 10.1016/j.antiviral.2021.105127.
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    June 2021
  11. DO TND, Donckers K, Vangeel L, Chatterjee AK, et al
    A robust SARS-CoV-2 replication model in primary human epithelial cells at the air liquid interface to assess antiviral agents.
    Antiviral Res. 2021 Jun 26:105122. doi: 10.1016/j.antiviral.2021.105122.
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  12. KASHYAP T, Murray J, Walker CJ, Chang H, et al
    Selinexor, a novel selective inhibitor of nuclear export, reduces SARS-CoV-2 infection and protects the respiratory system in vivo.
    Antiviral Res. 2021 Jun 19:105115. doi: 10.1016/j.antiviral.2021.105115.
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    May 2021
  13. CHONG Y, Kawai N, Tani N, Bando T, et al
    Virological and clinical outcomes in outpatients treated with baloxavir or oseltamivir: A Japanese multicenter study in the 2019-2020 influenza season.
    Antiviral Res. 2021;192:105092.
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    April 2021
  14. SVYATCHENKO SV, Goncharova NI, Marchenko VY, Kolosova NP, et al
    An influenza A(H5N8) virus isolated during an outbreak at a poultry farm in Russia in 2017 has an N294S substitution in the neuraminidase and shows reduced susceptibility to oseltamivir.
    Antiviral Res. 2021 Apr 29:105079. doi: 10.1016/j.antiviral.2021.105079.
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  15. ZHAO J, Guo S, Yi D, Li Q, et al
    A cell-based assay to discover inhibitors of SARS-CoV-2 RNA dependent RNA polymerase.
    Antiviral Res. 2021;190:105078.
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  16. DU R, Cooper L, Chen Z, Lee H, et al
    Discovery of Chebulagic Acid and Punicalagin as Novel Allosteric Inhibitors of SARS-CoV-2 3CL(pro).
    Antiviral Res. 2021 Apr 16:105075. doi: 10.1016/j.antiviral.2021.105075.
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    March 2021
  17. CICCOSANTI F, Di Rienzo M, Romagnoli A, Colavita F, et al
    Proteomic Analysis Identifies the RNA Helicase DDX3X as a Host Target Against SARS-CoV-2 Infection.
    Antiviral Res. 2021 Mar 26:105064. doi: 10.1016/j.antiviral.2021.105064.
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  18. ROOSENHOFF R, Schutten M, Reed V, Clinch B, et al
    Secondary substitutions in the hemagglutinin and neuraminidase genes associated with neuraminidase inhibitor resistance are rare in the Influenza Resistance Information Study (IRIS).
    Antiviral Res. 2021 Mar 10:105060. doi: 10.1016/j.antiviral.2021.105060.
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  19. MILANI M, Donalisio M, Bonotto RM, Schneider E, et al
    Combined in silico and in vitro approaches identified the antipsychotic drug lurasidone and the antiviral drug elbasvir as SARS-CoV2 and HCoV-OC43 inhibitors.
    Antiviral Res. 2021 Mar 10:105055. doi: 10.1016/j.antiviral.2021.105055.
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    February 2021
  20. PATEL MC, Chesnokov A, Jones J, Mishin VP, et al
    Susceptibility of widely diverse influenza a viruses to PB2 polymerase inhibitor pimodivir.
    Antiviral Res. 2021;188:105035.
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  21. HIDEKAZU OSADA, Chon I, Phyu WW, Wagatsuma K, et al
    Development of cycling probe based real-time PCR methodology for influenza A viruses possessing the PA/I38T amino acid substitution associated with reduced baloxavir susceptibility.
    Antiviral Res. 2021 Feb 9:105036. doi: 10.1016/j.antiviral.2021.105036.
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  22. MARTIN R, Li J, Parvangada A, Perry J, et al
    Genetic Conservation of SARS-CoV-2 RNA Replication Complex in Globally Circulating Isolates and Recently Emerged Variants from Humans and Minks Suggests Minimal Pre-Existing Resistance to Remdesivir.
    Antiviral Res. 2021 Feb 4:105033. doi: 10.1016/j.antiviral.2021.105033.
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    January 2021
  23. LIU C, Boland S, Scholle MD, Bardiot D, et al
    Dual Inhibition of SARS-CoV-2 and Human Rhinovirus with Protease Inhibitors in Clinical Development.
    Antiviral Res. 2021 Jan 27:105020. doi: 10.1016/j.antiviral.2021.105020.
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  24. ZHU Q, Zhang Y, Wang L, Yao X, et al
    Inhibition of coronavirus infection by a synthetic STING agonist in primary human airway system.
    Antiviral Res. 2021 Jan 11:105015. doi: 10.1016/j.antiviral.2021.105015.
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  25. DU R, Cheng H, Cui Q, Peet NP, et al
    Identification of a novel inhibitor targeting influenza A virus group 2 hemagglutinins.
    Antiviral Res. 2021;186:105013.
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    November 2020
  26. SVENNINGSEN EB, Thyrsted J, Blay-Cadanet J, Liu H, et al
    Ionophore antibiotic X-206 is a potent inhibitor of SARS-CoV-2 infection in vitro.
    Antiviral Res. 2020 Nov 25:104988. doi: 10.1016/j.antiviral.2020.104988.
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  27. ZHANG Y, Song W, Chen S, Yuan Z, et al
    A bacterial artificial chromosome (BAC)-vectored noninfectious replicon of SARS-CoV-2.
    Antiviral Res. 2020 Nov 17:104974. doi: 10.1016/j.antiviral.2020.104974.
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  28. HEJDANEK J, Radilova K, Pachl P, Hodek J, et al
    Structural characterization of the interaction between the C-terminal domain of the influenza polymerase PA subunit and an optimized small peptide inhibitor.
    Antiviral Res. 2020 Nov 6:104971. doi: 10.1016/j.antiviral.2020.104971.
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  29. ZARAKET H, Hurt AC, Clinch B, Barr I, et al
    Burden of influenza B virus infection and considerations for clinical management.
    Antiviral Res. 2020 Nov 4:104970. doi: 10.1016/j.antiviral.2020.104970.
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    October 2020
  30. CHOI SW, Shin JS, Park SJ, Jung E, et al
    Antiviral activity and safety of remdesivir against SARS-CoV-2 infection in human pluripotent stem cell-derived cardiomyocytes.
    Antiviral Res. 2020 Oct 19:104955. doi: 10.1016/j.antiviral.2020.104955.
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    September 2020
  31. SAITO R, Osada H, Wagatsuma K, Chon I, et al
    Duration of fever and symptoms in children after treatment with baloxavir marboxil and oseltamivir during the 2018-2019 season and detection of variant influenza a viruses with polymerase acidic subunit substitutions.
    Antiviral Res. 2020;183:104951.
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  32. ZHU Q, Hu H, Liu H, Shen H, et al
    A synthetic STING agonist inhibits the replication of Human Parainfluenza Virus 3 and Rhinovirus 16 through distinct mechanisms.
    Antiviral Res. 2020 Sep 16:104933. doi: 10.1016/j.antiviral.2020.104933.
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  33. THEERAWATANASIRIKUL S, Kuo CJ, Phecharat N, Chootip J, et al
    Structural-based virtual screening and in vitro assays for small molecules inhibiting the feline coronavirus 3CL protease as a surrogate platform for coronaviruses.
    Antiviral Res. 2020 Sep 7:104927. doi: 10.1016/j.antiviral.2020.104927.
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  34. GURARD-LEVIN ZA, Liu C, Jekle A, Jaisinghani R, et al
    Evaluation of SARS-CoV-2 3C-like protease inhibitors using self-assembled monolayer desorption ionization mass spectrometry.
    Antiviral Res. 2020 Sep 4:104924. doi: 10.1016/j.antiviral.2020.104924.
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    August 2020
  35. PATEL MC, Mishin VP, De La Cruz JA, Chesnokov A, et al
    Detection of baloxavir resistant influenza A viruses using next generation sequencing and pyrosequencing methods.
    Antiviral Res. 2020 Aug 13:104906. doi: 10.1016/j.antiviral.2020.104906.
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  36. LI W, Li J, Sun M, Yang L, et al
    Viperin protein inhibits the replication of caprine parainfluenza virus 3 (CPIV 3) by interaction with viral N protein.
    Antiviral Res. 2020 Aug 12:104903. doi: 10.1016/j.antiviral.2020.104903.
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  37. KONKOLOVA E, Dejmek M, Hrebabecky H, Sala M, et al
    Remdesivir triphosphate can efficiently inhibit the RNA-dependent RNA polymerase from various flaviviruses.
    Antiviral Res. 2020 Aug 4:104899. doi: 10.1016/j.antiviral.2020.104899.
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  38. MOHR PG, Williams J, Tashiro M, Streltsov VA, et al
    Substitutions at H134 and in the 430-loop region in influenza B neuraminidases can confer reduced susceptibility to multiple neuraminidase inhibitors.
    Antiviral Res. 2020 Aug 1:104895. doi: 10.1016/j.antiviral.2020.104895.
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  39. BIALY D, Shelton H
    Functional neuraminidase inhibitor resistance motifs in avian influenza A(H5Nx) viruses.
    Antiviral Res. 2020 Aug 1:104886. doi: 10.1016/j.antiviral.2020.104886.
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    July 2020
  40. OKAMOTO M, Toyama M, Baba M
    The chemokine receptor antagonist cenicriviroc inhibits the replication of SARS-CoV-2 in vitro.
    Antiviral Res. 2020 Jul 30:104902. doi: 10.1016/j.antiviral.2020.104902.
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  41. CONZELMANN C, Gilg A, Gross R, Schutz D, et al
    An enzyme-based immunodetection assay to quantify SARS-CoV-2 infection.
    Antiviral Res. 2020 Jul 29:104882. doi: 10.1016/j.antiviral.2020.104882.
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  42. CAI W, Wen H, Zhou Q, Wu L, et al
    14-Deoxy-11,12-didehydroandrographolide inhibits apoptosis in influenza A(H5N1) virus-infected human lung epithelial cells via the caspase-9-dependent intrinsic apoptotic pathway which contributes to its antiviral activity.
    Antiviral Res. 2020 Jul 20:104885. doi: 10.1016/j.antiviral.2020.104885.
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  43. GALLIAN P, Pastorino B, Morel P, Chiaroni J, et al
    Lower prevalence of antibodies neutralizing SARS-CoV-2 in group O French blood donors.
    Antiviral Res. 2020 Jul 14:104880. doi: 10.1016/j.antiviral.2020.104880.
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  44. PIZZORNO A, Padey B, Dubois J, Julien T, et al
    In vitro evaluation of antiviral activity of single and combined repurposable drugs against SARS-CoV-2.
    Antiviral Res. 2020 Jul 14:104878. doi: 10.1016/j.antiviral.2020.104878.
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  45. VENISSE N, Peytavin G, Bouchet S, Gagnieu MC, et al
    Concerns about pharmacokinetic (PK) and pharmacokinetic-pharmacodynamic (PK-PD) studies in the new therapeutic area of COVID-19 infection.
    Antiviral Res. 2020 Jul 10:104866. doi: 10.1016/j.antiviral.2020.104866.
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  46. PAN X, Zhou P, Fan T, Wu Y, et al
    Immunoglobulin fragment F(ab')2 against RBD potently neutralizes SARS-CoV-2 in vitro.
    Antiviral Res. 2020 Jul 10:104868. doi: 10.1016/j.antiviral.2020.104868.
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  47. KIM SY, Jin W, Sood A, Montgomery DW, et al
    Characterization of heparin and severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) spike glycoprotein binding interactions.
    Antiviral Res. 2020 Jul 9:104873. doi: 10.1016/j.antiviral.2020.104873.
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  48. SALINAS FM, Nebreda AD, Vazquez L, Gentilini MV, et al
    Imiquimod suppresses respiratory syncytial virus (RSV) replication via PKA pathway and reduces RSV induced-inflammation and viral load in mice lungs.
    Antiviral Res. 2020;179:104817.
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    June 2020
  49. MATYUSHENKO V, Kotomina T, Kudryavtsev I, Mezhenskaya D, et al
    Conserved T-cell epitopes of respiratory syncytial virus (RSV) delivered by recombinant live attenuated influenza vaccine viruses efficiently induce RSV-specific lung-localized memory T cells and augment influenza-specific resident memory T-cell respo
    Antiviral Res. 2020 Jun 22:104864. doi: 10.1016/j.antiviral.2020.104864.
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  50. TAKASHITA E, Abe T, Morita H, Nagata S, et al
    Influenza A(H1N1)pdm09 virus exhibiting reduced susceptibility to baloxavir due to a PA E23K substitution detected from a child without baloxavir treatment.
    Antiviral Res. 2020 Jun 20:104828. doi: 10.1016/j.antiviral.2020.104828.
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  51. JOCKUSCH S, Tao C, Li X, Anderson TK, et al
    A library of nucleotide analogues terminate RNA synthesis catalyzed by polymerases of coronaviruses that cause SARS and COVID-19.
    Antiviral Res. 2020;180:104857.
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  52. TILMANIS D, Koszalka P, Barr IG, Rossignol JF, et al
    Host-targeted Nitazoxanide has a high barrier to resistance but does not reduce the emergence or proliferation of oseltamivir-resistant influenza viruses in vitro or in vivo when used in combination with oseltamivir.
    Antiviral Res. 2020 Jun 13:104851. doi: 10.1016/j.antiviral.2020.104851.
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  53. SHANNON A, Le NT, Selisko B, Eydoux C, et al
    Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites.
    Antiviral Res. 2020;178:104793.
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    May 2020
  54. TAI W, Zhang X, He Y, Jiang S, et al
    Identification of SARS-CoV RBD-targeting monoclonal antibodies with cross-reactive or neutralizing activity against SARS-CoV-2.
    Antiviral Res. 2020 May 13:104820. doi: 10.1016/j.antiviral.2020.104820.
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  55. BLOCKUS S, Sake SM, Wetzke M, Grethe C, et al
    Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry.
    Antiviral Res. 2020;177:104774.
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    April 2020
  56. MANTLO E, Bukreyeva N, Maruyama J, Paessler S, et al
    Antiviral activities of type I interferons to SARS-CoV-2 infection.
    Antiviral Res. 2020;179:104811.
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  57. ABED Y, Fage C, Checkmahomed L, Venable MC, et al
    Characterization of contemporary influenza B recombinant viruses harboring mutations of reduced susceptibility to baloxavir marboxil, in vitro and in mice.
    Antiviral Res. 2020 Apr 25:104807. doi: 10.1016/j.antiviral.2020.104807.
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  58. BRAY M, Rayner C, Noel F, Jans D, et al
    Ivermectin and COVID-19: a report in Antiviral Research, widespread interest, an FDA warning, two letters to the editor and the authors' responses.
    Antiviral Res. 2020 Apr 21:104805. doi: 10.1016/j.antiviral.2020.104805.
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  59. LAURE M, Hamza H, Koch-Heier J, Quernheim M, et al
    Antiviral efficacy against Influenza virus and pharmacokinetic analysis of a novel MEK-inhibitor, ATR-002, in cell culture and in the mouse model.
    Antiviral Res. 2020 Apr 15:104806. doi: 10.1016/j.antiviral.2020.104806.
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  60. SALLARD E, Lescure FX, Yazdanpanah Y, Mentre F, et al
    Type 1 interferons as a potential treatment against COVID-19.
    Antiviral Res. 2020;178:104791.
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  61. SUZUKI S, Shichinohe S, Itoh Y, Nakayama M, et al
    Low replicative fitness of neuraminidase inhibitor-resistant H7N9 avian influenza A virus with R292K substitution in neuraminidase in cynomolgus macaques compared with I222T substitution.
    Antiviral Res. 2020 Apr 6:104790. doi: 10.1016/j.antiviral.2020.104790.
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  62. TANG T, Bidon M, Jaimes JA, Whittaker GR, et al
    Coronavirus membrane fusion mechanism offers as a potential target for antiviral development.
    Antiviral Res. 2020 Apr 6:104792. doi: 10.1016/j.antiviral.2020.104792.
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  63. CALY L, Druce JD, Catton MG, Jans DA, et al
    The FDA-approved Drug Ivermectin inhibits the replication of SARS-CoV-2 in vitro.
    Antiviral Res. 2020 Apr 3:104787. doi: 10.1016/j.antiviral.2020.104787.
    >> Share

  64. CHOY KT, Yin-Lam Wong A, Kaewpreedee P, Sia SF, et al
    Remdesivir, lopinavir, emetine, and homoharringtonine inhibit SARS-CoV-2 replication in vitro.
    Antiviral Res. 2020 Apr 3:104786. doi: 10.1016/j.antiviral.2020.104786.
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    March 2020
  65. SOLDEVILA N, Toledo D, Ortiz de Lejarazu R, Tamames S, et al
    Effect of antiviral treatment in older patients hospitalized with confirmed influenza.
    Antiviral Res. 2020 Mar 29:104785. doi: 10.1016/j.antiviral.2020.104785.
    >> Share

  66. JALILY PH, Duncan MC, Fedida D, Wang J, et al
    Put a cork in it: Plugging the M2 viral ion channel to sink influenza.
    Antiviral Res. 2020 Mar 27:104780. doi: 10.1016/j.antiviral.2020.104780.
    >> Share

  67. HUSSEIN AFA, Cheng H, Tundup S, Antanasijevic A, et al
    Identification of entry inhibitors with 4-aminopiperidine scaffold targeting group 1 influenza A virus.
    Antiviral Res. 2020 Mar 25:104782. doi: 10.1016/j.antiviral.2020.104782.
    >> Share

  68. SLOAN SE, Szretter KJ, Sundaresh B, Narayan KM, et al
    Clinical and virological responses to a broad-spectrum human monoclonal antibody in an influenza virus challenge study.
    Antiviral Res. 2020 Mar 6:104763. doi: 10.1016/j.antiviral.2020.104763.
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  69. TOURET F, de Lamballerie X
    Of chloroquine and COVID-19.
    Antiviral Res. 2020;177:104762.
    >> Share

  70. SIGRIST C, Bridge A, Le Mercier P
    A potential role for integrins in host cell entry by SARS-CoV-2.
    Antiviral Res. 2020 Mar 1:104759. doi: 10.1016/j.antiviral.2020.104759.
    >> Share

    February 2020
  71. QIU H, Andersen H, Tarbet EB, Muhammad FS, et al
    Efficacy of anti-influenza immunoglobulin (FLU-IGIV) in ferrets and mice infected with 2009 pandemic influenza virus.
    Antiviral Res. 2020 Feb 27:104753. doi: 10.1016/j.antiviral.2020.104753.
    >> Share

  72. KUMARI R, Guo Z, Kumar A, Wiens M, et al
    Influenza virus NS1- C/EBPbeta gene regulatory complex inhibits RIG-I transcription.
    Antiviral Res. 2020 Feb 21:104747. doi: 10.1016/j.antiviral.2020.104747.
    >> Share

  73. MIFSUD EJ, Tilmanis D, Oh DY, Ming-Kay Tai C, et al
    Prophylaxis of ferrets with nitazoxanide and oseltamivir combinations is more effective at reducing the impact of influenza a virus infection compared to oseltamivir monotherapy.
    Antiviral Res. 2020 Feb 20:104751. doi: 10.1016/j.antiviral.2020.104751.
    >> Share

    January 2020
  74. TAKASHITA E, Daniels RS, Fujisaki S, Gregory V, et al
    Global update on the susceptibilities of human influenza viruses to neuraminidase inhibitors and the cap-dependent endonuclease inhibitor baloxavir, 2017-2018.
    Antiviral Res. 2020 Jan 28:104718. doi: 10.1016/j.antiviral.2020.104718.
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    November 2019
  75. PASCUA PNQ, Marathe BM, Bisen S, Webby RJ, et al
    Influenza B viruses from different genetic backgrounds are variably impaired by neuraminidase inhibitor resistance-associated substitutions.
    Antiviral Res. 2019 Nov 29:104669. doi: 10.1016/j.antiviral.2019.104669.
    >> Share

    February 2019
  76. SCHOGLER A, Caliaro O, Brugger M, Oliveira Esteves BI, et al
    Modulation of the unfolded protein response pathway as an antiviral approach in airway epithelial cells.
    Antiviral Res. 2019;162:44-50.
    >> Share

    January 2019
  77. ZHANG K, Li C, Luo YS, Wen L, et al
    Establishment of a lethal aged mouse model of human respiratory syncytial virus infection.
    Antiviral Res. 2019;161:125-133.
    >> Share


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