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Drug Resistance

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Articles published in
J Infect Dis
    September 2025
  1. PORETSKY RS, Gonzalez DS, Horton A, Schoeny M, et al
    Establishing a Practical Approach to Sewer Monitoring for Antimicrobial Resistance Genes and Organisms at Healthcare Facilities.
    J Infect Dis. 2025 Sep 24:jiaf434. doi: 10.1093.
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  2. SRIDHAR S, Worby CJ, Bronson RA, Turbett SE, et al
    Insights Into Global Antimicrobial Resistance Dynamics Through the Sequencing of Enteric Bacteria From US International Travelers.
    J Infect Dis. 2025 Sep 24:jiaf469. doi: 10.1093.
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  3. CARR MA, Chou SR, Sun J, LaRock DL, et al
    Therapeutic Inhibition of Metalloproteases by Tetracyclines During Infection by Multidrug-Resistant Pseudomonas.
    J Infect Dis. 2025;232:e416-e420.
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  4. GONTJES KJ, Singh A, Sansom SE, Boyko JD, et al
    Phylogenetic context of antibiotic resistance provides insights into the dynamics of resistance emergence and spread.
    J Infect Dis. 2025 Sep 15:jiaf478. doi: 10.1093.
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    August 2025
  5. ROBERTS M, Davis P
    Doxycycline post-exposure prophylaxis and off-target antimicrobial resistance: potential amplification within sexual networks.
    J Infect Dis. 2025 Aug 20:jiaf439. doi: 10.1093.
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  6. WATKINS RR, Lemonovich TL, Vila AJ, Bonomo RA, et al
    Cefepime-Taniborbactam-a Novel Combination Therapy for Multidrug-Resistant Pathogens.
    J Infect Dis. 2025;232:278-284.
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  7. CHOUDHURY NR, Urwin L, Salamaga B, Prince LR, et al
    Determining the importance of the stringent response for methicillin-resistant Staphylococcus aureus virulence in vivo.
    J Infect Dis. 2025 Aug 8:jiaf421. doi: 10.1093.
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  8. LIAO CH, Huang YL, Ioerger T, Lim KS, et al
    Genomic and phenotypic insights into antibiotic resistance and virulence of Klebsiella pneumoniae from the environment in Southern Taiwan.
    J Infect Dis. 2025 Aug 1:jiaf396. doi: 10.1093.
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    July 2025
  9. MARANO RBM, Oster Y, Benenson S, Motro Y, et al
    An Omics-Guided Investigation of a Hospital Outbreak Caused by blaNDM-1-Producing Pseudocitrobacter faecalis.
    J Infect Dis. 2025;232:e17-e26.
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  10. LAUMEN JGE, Hieu VN, Nhung PH, Vandelannoote K, et al
    High Prevalence of Ceftriaxone-Resistant Neisseria gonorrhoeae in Hanoi, Vietnam, 2023-2024.
    J Infect Dis. 2025;232:e73-e77.
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  11. CAILLAULT A, Softic L, Bay P, Ly A, et al
    Molecular Characterization of Respiratory Syncytial Virus Infections in Elderly Patients During the 2023-2024 Season in the Era of Nirsevimab Introduction.
    J Infect Dis. 2025;232:199-202.
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  12. SHIMUTA K, Ohama Y, Ito S, Hoshina S, et al
    Emergence of Ceftriaxone-Resistant Neisseria gonorrhoeae Through Horizontal Gene Transfer Among Neisseria Species.
    J Infect Dis. 2025;232:152-161.
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  13. TALBOT BM, Jacko NF, Hofstetter KS, Alahakoon T, et al
    Methicillin-Resistant Staphylococcus aureus Bacteremia Relapses Show Diverse Genomic Profiles but Convergence in Bacteremia-Associated Genes.
    J Infect Dis. 2025 Jul 25:jiaf352. doi: 10.1093.
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    June 2025
  14. NORGAARD JC, Marandi RZ, Ilett EE, Gulay A, et al
    The gut microbiome and its resistome as predictors of clinical infections and phenotypic antibiotic resistance in hematopoietic stem cell transplant recipients.
    J Infect Dis. 2025 Jun 23:jiaf330. doi: 10.1093.
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  15. DOORLEY LA, Meza-Perez V, Jones SJ, Rybak JM, et al
    A Candidozyma (Candida) auris-Optimized Episomal Plasmid-Induced Cas9-Editing System Reveals the Direct Impact of the S639F-Encoding FKS1 Mutation.
    J Infect Dis. 2025 Jun 17:jiaf285. doi: 10.1093.
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  16. BUSTION AE, Ernest JP, Kaya F, Silva C, et al
    The kinetics of bedaquiline diffusion in tuberculous cavities open a window for emergence of resistance.
    J Infect Dis. 2025 Jun 4:jiaf303. doi: 10.1093.
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  17. YANG T, Beach KE, Zhu C, Gan M, et al
    Genomic Analysis of Global Mycobacterium abscessus Isolates Reveals Ongoing Evolution of Drug Resistance-Associated Genes.
    J Infect Dis. 2025;231:1150-1154.
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    May 2025
  18. LI Y, Stellfox ME, Evans KM, Mills EG, et al
    Functional genomics of antibiotic susceptibility in Enterococcus faecalis from infective endocarditis.
    J Infect Dis. 2025 May 30:jiaf272. doi: 10.1093.
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    April 2025
  19. MOGENI P, Ochieng JB, Atlas HE, Tickell KD, et al
    Impact of macrolide resistance on azithromycin for prevention of rehospitalization or death among children discharged from hospitals in Western Kenya.
    J Infect Dis. 2025 Apr 21:jiaf208. doi: 10.1093.
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  20. PARK H, Abrams JA, Uhlemann AC, Freedberg DE, et al
    Gut colonization with vancomycin-resistant Enterococcus shapes the gut microbiome in the intensive care unit.
    J Infect Dis. 2025 Apr 16:jiaf194. doi: 10.1093.
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  21. MASTERS TL, Toney NC, Ewing TO, McAllister GA, et al
    Genomic Epidemiology of Extrapulmonary Nontuberculous Mycobacteria Isolates at Emerging Infections Program Sites-United States, 2019-2020.
    J Infect Dis. 2025;231:902-912.
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    March 2025
  22. PARAU G, Parks HJ, Anderson AJG, Bisaro F, et al
    Clinical isolates of antimicrobial resistant Enterobacter species can persist in human macrophages without replication and overt cellular cytotoxicity.
    J Infect Dis. 2025 Mar 3:jiaf099. doi: 10.1093.
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    February 2025
  23. LEVENE RE, DeVincenzo J, Conery AL, Ahmad A, et al
    EDP-938 Has a High Barrier to Resistance in Healthy Adults Experimentally Infected with Respiratory Syncytial Virus.
    J Infect Dis. 2025;231:e290-e298.
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  24. GASPAR C, Rios P, Moeller TD
    Landscape of Bacterial Enteric Disease and Traveler s Diarrhea in South America.
    J Infect Dis. 2025;231.
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    January 2025
  25. MARGOT NA, Jogiraju V, Pennetzdorfer N, Naik V, et al
    Resistance Analyses in Heavily Treatment-Experienced People with HIV Treated with the Novel HIV Capsid Inhibitor Lenacapavir After 2 years.
    J Infect Dis. 2025 Jan 28:jiaf050. doi: 10.1093.
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  26. JANKEEL A, Perez-Parra G, Khetarpal AK, Alvarado IA, et al
    Enhanced Killing of Methicillin-Resistant Staphylococcus aureus with Ceftaroline or Vancomycin in Combination with Carbapenems.
    J Infect Dis. 2025 Jan 8:jiaf010. doi: 10.1093.
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    December 2024
  27. LI Y, Mishra NN, Chen L, Manna AC, et al
    Phage-Encoded Virulence Factor, Gp05, Alters Membrane Phospholipids and Reduces Antimicrobial Susceptibility in Methicillin-Resistant Staphylococcus aureus.
    J Infect Dis. 2024 Dec 31:jiae640. doi: 10.1093.
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  28. NTOZINI B, Walaza S, Metcalf B, Hazelhurst S, et al
    Molecular epidemiology of invasive group B Streptococcus in South Africa, 2019-2020.
    J Infect Dis. 2024 Dec 31:jiae633. doi: 10.1093.
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  29. MITTELSTAEDT R, Kanjilal S, Helekal D, Robbins GK, et al
    Staphylococcus aureus Tetracycline Resistance and Co-resistance in a Doxy-PEP-Eligible Population.
    J Infect Dis. 2024 Dec 24:jiae634. doi: 10.1093.
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  30. MIKHARI RL, Meiring S, de Gouveia L, Chan WY, et al
    Genomic Diversity and Antimicrobial Susceptibility of Invasive Neisseria meningitidis in South Africa, 2016-2021.
    J Infect Dis. 2024;230:e1311-e1321.
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    November 2024
  31. JACQUELINE C, Minetti C, Monzon Fernandez S, Silveira L, et al
    Genomic epidemiology of fluoroquinolone-resistant strains of Shigella sonnei and Shigella flexneri in the Iberian Peninsula from 2015 to 2022.
    J Infect Dis. 2024 Nov 29:jiae596. doi: 10.1093.
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    October 2024
  32. MACLEAN AKW, Morrow S, Niu F, Hanson ND, et al
    What Contributes to the Minimum Inhibitory Concentration? Beyond beta-Lactamase Gene Detection in Klebsiella pneumoniae.
    J Infect Dis. 2024;230:e777-e788.
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  33. SANSOM SE, Shimasaki T, Dangana T, Lin MY, et al
    Comparison of Daily Versus Admission and Discharge Surveillance Cultures for Multidrug-Resistant Organism Detection in an Intensive Care Unit.
    J Infect Dis. 2024;230:807-815.
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  34. RAJAGOPALAN S, Rourke AK, Asare E, Kohlerschmidt DJ, et al
    Engineered Mycobacteriophage TM4::GeNL Rapidly Determines Bedaquiline, Pretomanid, Linezolid, Rifampicin, and Clofazimine Sensitivity in Mycobacterium tuberculosis Clinical Isolates.
    J Infect Dis. 2024 Oct 16:jiae438. doi: 10.1093.
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  35. GAWOR J, Zuchniewicz K, Ojeda Saavedra M, Beres SB, et al
    ICESp1109, a novel hybrid Integrative Conjugative Element of macrolide-resistant Streptococcus pyogenes serotype M77 collected between 2003 and 2017 in Poland.
    J Infect Dis. 2024 Oct 12:jiae473. doi: 10.1093.
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    September 2024
  36. CHOU S, Winston DJ, Avery RK, Cordonnier C, et al
    Comparative Emergence of Maribavir and Ganciclovir Resistance in a Randomized Phase 3 Clinical Trial for Treatment of Cytomegalovirus Infection.
    J Infect Dis. 2024 Sep 20:jiae469. doi: 10.1093.
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    August 2024
  37. NAGELE K, Battig V, Gosert R, Walti CS, et al
    Revealing the unseen: next generation sequencing for early detection of drug-resistant cytomegalovirus variants upon letermovir prophylaxis failure.
    J Infect Dis. 2024 Aug 30:jiae414. doi: 10.1093.
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  38. YE J, Dong Y, Lan Y, Chen J, et al
    Trends and Patterns of HIV Transmitted Drug Resistance in China From 2018 to 2023.
    J Infect Dis. 2024 Aug 27:jiae303. doi: 10.1093.
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  39. YEK C, Lon C, Chea S, Lay S, et al
    Bacterial Genomics for National Antimicrobial Resistance Surveillance in Cambodia.
    J Infect Dis. 2024 Aug 20:jiae417. doi: 10.1093.
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  40. CHOUDHARY MC, Deo R, Evering TH, Chew KW, et al
    Characterization of Treatment Resistance and Viral Kinetics in the Setting of Single-Active Versus Dual-Active Monoclonal Antibodies Against Severe Acute Respiratory Syndrome Coronavirus 2.
    J Infect Dis. 2024;230:394-402.
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  41. CHOCHUA S, Beall B, Lin W, Tran T, et al
    The emergent invasive serotype 4 ST10172 strain acquires vanG type vancomycin-resistance element: A case of a 66-year-old with bacteremic pneumococcal pneumonia.
    J Infect Dis. 2024 Aug 8:jiae393. doi: 10.1093.
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    July 2024
  42. TANTALO LC, Luetkemeyer A, Lieberman NAP, Nunley BE, et al
    Long-term in vitro exposure of Treponema pallidum to sub-bactericidal doxycycline did not induce resistance: Implications for doxy-PEP and syphilis.
    J Infect Dis. 2024 Jul 27:jiae381. doi: 10.1093.
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  43. BURDORF RM, Zhou S, Amon C, Long N, et al
    Impact of Low-Frequency Human Immunodeficiency Virus Type 1 Drug Resistance Mutations on Antiretroviral Therapy Outcomes.
    J Infect Dis. 2024;230:86-94.
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  44. GUITOR AK, Katyukhina A, Mokomane M, Lechiile K, et al
    Minimal Impact on the Resistome of Children in Botswana After Azithromycin Treatment for Acute Severe Diarrheal Disease.
    J Infect Dis. 2024;230:239-249.
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  45. HENRY SA, Webster CM, Shaw LN, Torres NJ, et al
    Steroid Drugs Inhibit Bacterial Respiratory Oxidases and Are Lethal Toward Methicillin-Resistant Staphylococcus aureus.
    J Infect Dis. 2024;230:e149-e158.
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  46. AUNG S, Novitsky V, Steingrimsson J, Gillani FS, et al
    Acquired Human Immunodeficiency Virus Type 1 Drug Resistance in Rhode Island, USA, 2004-2021.
    J Infect Dis. 2024 Jul 23:jiae344. doi: 10.1093.
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  47. BLECHMAN SE, Wright ES
    Applications of machine learning on electronic health record data to combat antibiotic resistance.
    J Infect Dis. 2024 Jul 12:jiae348. doi: 10.1093.
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  48. ZHOU S, Long N, Rosenke K, Jarvis MA, et al
    Combined Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 Reduces Molnupiravir-Induced Mutagenicity and Prevents Selection for Nirmatrelvir/Ritonavir Resistance Mutations.
    J Infect Dis. 2024 Jul 8:jiae213. doi: 10.1093.
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    June 2024
  49. CHOW EPF, Stevens K, De Petra V, Chen MY, et al
    Prevalence of cefixime-resistant Neisseria gonorrhoeae in Melbourne, Australia, 2021-2022.
    J Infect Dis. 2024 Jun 15:jiae313. doi: 10.1093.
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  50. SOKAL A, Royer G, Esposito-Farese M, Clermont O, et al
    Clinical and Bacteriological Specificities of Escherichia coli Bloodstream Infections From Biliary Portal of Entries.
    J Infect Dis. 2024;229:1679-1687.
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  51. DAI T, Ma C, Zhang F, Wang H, et al
    The Efficacy and Safety of an Intra-articular Dual-Acting Antibacterial Agent (TNP-2092) for Implant Infection-Associated Methicillin-Resistant Staphylococcus aureus.
    J Infect Dis. 2024;229:1658-1668.
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  52. STRIZKI JM, Diamond TL, Teal VL, Gilbert CL, et al
    Cytomegalovirus antiviral resistance among participants in the phase 3 trial of letermovir vs valganciclovir prophylaxis in kidney transplant recipients.
    J Infect Dis. 2024 Jun 10:jiae287. doi: 10.1093.
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    May 2024
  53. DIXIT A, Ektefaie Y, Kagal A, Freschi L, et al
    Drug resistance and epidemiological success of modern Mycobacterium tuberculosis lineages in western India.
    J Infect Dis. 2024 May 31:jiae240. doi: 10.1093.
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  54. MCCLUSKEY SM, Muyindike WR, Nanfuka V, Omoding D, et al
    Population Effectiveness of Dolutegravir Implementation in Uganda - A Prospective Observational Cohort Study (DISCO): 48-week Results.
    J Infect Dis. 2024 May 16:jiae260. doi: 10.1093.
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  55. TAGAMI Y, Horita N, Kaneko M, Muraoka S, et al
    Whole-Genome Sequencing Predicting Phenotypic Antitubercular Drug Resistance: Meta-analysis.
    J Infect Dis. 2024;229:1481-1492.
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  56. KU JH, Tartof SY, Contreras R, Ackerson BK, et al
    Antibiotic resistance of urinary tract infection recurrences in a large U.S. integrated health care system.
    J Infect Dis. 2024 May 14:jiae233. doi: 10.1093.
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  57. COSTA C, Sirard JC, Gibson PS, Veening JW, et al
    Triggering Toll-Like Receptor 5 signaling during pneumococcal superinfection prevents the selection of antibiotic resistance.
    J Infect Dis. 2024 May 8:jiae239. doi: 10.1093.
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    April 2024
  58. MILLER WR, Nguyen A, Singh KV, Rizvi S, et al
    Membrane Lipids Augment Cell Envelope Stress Signaling via the MadRS System to Defend Against Antimicrobial Peptides and Antibiotics in Enterococcus faecalis.
    J Infect Dis. 2024 Apr 5:jiae173. doi: 10.1093.
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    March 2024
  59. BROUGH SC, Caddell L, Liou RJ, Patil A, et al
    Predicting Increased Incidence of Common Antibiotic-Resistant and Antibiotic-Associated Pathogens Using Ensemble Species Distribution Modeling.
    J Infect Dis. 2024 Mar 27:jiae145. doi: 10.1093.
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    February 2024
  60. PENG KT, Chen PC, Chen JL, Huang TY, et al
    A comparative phenotypic and genomic analysis of methicillin-resistant Staphylococcus aureus ST45 isolates from cellulitis and from osteomyelitis in Taiwan.
    J Infect Dis. 2024 Feb 26:jiae096. doi: 10.1093.
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  61. SAUVE K, Watson A, Oh JT, Swift S, et al
    The Engineered Lysin, CF-370, is Active Against Antibiotic-Resistant Gram-Negative Pathogens In vitro and Synergizes with Meropenem in Experimental Pseudomonas aeruginosa Pneumonia.
    J Infect Dis. 2024 Feb 15:jiae027. doi: 10.1093.
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  62. HENRY SA, Webster CM, Shaw LN, Torres NJ, et al
    Steroid Drugs Inhibit Bacterial Respiratory Oxidases and Are Lethal Toward Methicillin-Resistant Staphylococcus aureus.
    J Infect Dis. 2024 Feb 13:jiad540. doi: 10.1093.
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    January 2024
  63. XIONG YQ, Li Y, Goncheva MI, Elsayed AM, et al
    The Purine Biosynthesis Repressor, PurR, Contributes to Vancomycin Susceptibility of Methicillin-resistant Staphylococcus aureus in Experimental Endocarditis.
    J Infect Dis. 2024 Jan 31:jiad577. doi: 10.1093.
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  64. GIAMMARINO F, de Salazar A, Malet I, Vinuela L, et al
    Prevalence and phenotypic susceptibility to doravirine of the HIV-1 reverse transcriptase V106I polymorphism in B and non-B subtypes.
    J Infect Dis. 2024 Jan 11:jiae010. doi: 10.1093.
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  65. VENTURINI C, Colston JM, Charles O, Lankina A, et al
    Persistent low-level variants in a subset of viral genes are highly predictive of poor outcome in immunocompromised patients with cytomegalovirus infection.
    J Infect Dis. 2024 Jan 5:jiae001. doi: 10.1093.
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    December 2023
  66. SMITH RA, Raugi DN, Nixon RS, Seydi M, et al
    Antiviral Activity of Lenacapavir Against HIV-2 Isolates and Drug-resistant HIV-2 Mutants.
    J Infect Dis. 2023 Dec 7:jiad562. doi: 10.1093.
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    November 2023
  67. PHILLIPS LT, Witney AA, Furegato M, Laing KG, et al
    Time Required for Nanopore Whole-Genome Sequencing of Neisseria gonorrhoeae for Identification of Phylogenetic Relationships.
    J Infect Dis. 2023;228:1179-1188.
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    September 2023
  68. ANDREEV K, Jones JC, Seiler P, Kandeil A, et al
    Antiviral Susceptibility of Highly Pathogenic Avian Influenza A(H5N1) Viruses Circulating Globally in 2022-2023.
    J Infect Dis. 2023 Sep 28:jiad418. doi: 10.1093.
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    July 2023
  69. CHOU S, Alain S, Cervera C, Chemaly RF, et al
    Drug Resistance Assessed in a Phase 3 Clinical Trial of Maribavir Therapy for Refractory or Resistant Cytomegalovirus Infection in Transplant Recipients.
    J Infect Dis. 2023 Jul 28:jiad293. doi: 10.1093.
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  70. HU Z, Cordwell T, Nguyen H, Li J, et al
    Effect of the L74I Polymorphism on Fitness of Cabotegravir-Resistant Variants of HIV-1 Subtype A6.
    J Infect Dis. 2023 Jul 27:jiad291. doi: 10.1093.
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    June 2023
  71. SINGH DK, Bhaskar A, Pahuja I, Shaji A, et al
    Co-treatment with Clofazimine and Rapamycin eliminates drug-resistant tuberculosis by inducing polyfunctional central memory T cell responses.
    J Infect Dis. 2023 Jun 8:jiad214. doi: 10.1093.
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    May 2023
  72. SCHALKWIJK HH, Georgala A, Gillemot S, Temblador A, et al
    A Herpes Simplex virus 1 DNA Polymerase Multidrug Resistance Mutation Identified in an Immunocompromised Patient - Confirmed by Gene Editing.
    J Infect Dis. 2023 May 24:jiad184. doi: 10.1093.
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