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Drug Resistance

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Articles published in
PLoS Genet
    May 2026
  1. ROULEAU FD, Dube AK, Pageau A, Desautels L, et al
    Predicting antifolate resistance in the unculturable fungal pathogen Pneumocystis jirovecii.
    PLoS Genet. 2026;22:e1012163.
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    March 2026
  2. HARRISON MC, Rinker DC, LaBella AL, Opulente DA, et al
    Machine learning identifies novel signatures of antifungal drug resistance in Saccharomycotina yeasts.
    PLoS Genet. 2026;22:e1012091.
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    February 2026
  3. BAUTISTA DE, Carr JF, Whitehead CR, Kostoch B, et al
    Loss of DNA mismatch repair genes leads to acquisition of antibiotic resistance independent of secondary mutations.
    PLoS Genet. 2026;22:e1012057.
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    December 2025
  4. SILVA KPT, Martini AM, Khare A
    Modulators of gene amplification alter evolution of antibiotic resistance in Staphylococcus aureus.
    PLoS Genet. 2025;21:e1012011.
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    September 2025
  5. LEON G, Brynildsen MP
    Conservation and divergence of ciprofloxacin persister survival mechanisms between Pseudomonas aeruginosa and Escherichia coli.
    PLoS Genet. 2025;21:e1011840.
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    August 2025
  6. SANCHEZ-MAROTO L, Devin GA, Gella P, Couce A, et al
    Idiosyncratic evolvability among single-point ribosomal mutants towards multi-aminoglycoside resistance.
    PLoS Genet. 2025;21:e1011832.
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    July 2025
  7. KIM T, Hong B, Northcote R, O'Halloran TV, et al
    Reversion of a RND transporter pseudogene reveals latent stress resistance potential in Brucella ovis.
    PLoS Genet. 2025;21:e1011795.
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    May 2025
  8. TRIGG AE, Sharma P, Grainger DC
    Coordination of cell envelope biology by Escherichia coli MarA protein potentiates intrinsic antibiotic resistance.
    PLoS Genet. 2025;21:e1011639.
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    April 2025
  9. ENGELGEH T, Wamp S, Rothe P, Herrmann J, et al
    ClpP2 proteasomes and SpxA1 determine Listeria monocytogenes tartrolon B hyper-resistance.
    PLoS Genet. 2025;21:e1011621.
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    March 2025
  10. SHIBAI A, Izutsu M, Kotani H, Furusawa C, et al
    Quantitative analysis of relationship between mutation rate and speed of adaptation under antibiotic exposure in Escherichia coli.
    PLoS Genet. 2025;21:e1011627.
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    February 2025
  11. RODRIGUEZ-GRANDE J, Ortiz Y, Garcia-Lopez D, Garcillan-Barcia MP, et al
    Encounter rates and engagement times limit the transmission of conjugative plasmids.
    PLoS Genet. 2025;21:e1011560.
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    October 2024
  12. NHU NTK, Forde BM, Ben Zakour NL, Phan MD, et al
    Evolution of the pheV-tRNA integrated genomic island in Escherichia coli.
    PLoS Genet. 2024;20:e1011459.
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    June 2024
  13. ELSEN S, Simon V, Attree I
    Cross-regulation and cross-talk of conserved and accessory two-component regulatory systems orchestrate Pseudomonas copper resistance.
    PLoS Genet. 2024;20:e1011325.
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    May 2024
  14. NAGARAJAN A, Scoggin K, Gupta J, Aminian M, et al
    Collaborative Cross mice have diverse phenotypic responses to infection with Methicillin-resistant Staphylococcus aureus USA300.
    PLoS Genet. 2024;20:e1011229.
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    April 2024
  15. ROULEAU FD, Dube AK, Gagnon-Arsenault I, Dibyachintan S, et al
    Deep mutational scanning of Pneumocystis jirovecii dihydrofolate reductase reveals allosteric mechanism of resistance to an antifolate.
    PLoS Genet. 2024;20:e1011252.
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    March 2024
  16. DJORIC D, Atkinson SN, Kristich CJ
    Reciprocal regulation of enterococcal cephalosporin resistance by products of the autoregulated yvcJ-glmR-yvcL operon enhances fitness during cephalosporin exposure.
    PLoS Genet. 2024;20:e1011215.
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    October 2023
  17. DURAND R, Jalbert-Ross J, Fijarczyk A, Dube AK, et al
    Cross-feeding affects the target of resistance evolution to an antifungal drug.
    PLoS Genet. 2023;19:e1011002.
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