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Articles published in
J Biol Chem
    March 2026
  1. HU R, Wang Y, Yagan M, Xu Y, et al
    Deregulated translation of the transcription factor Myt3 predisposes islet beta cells to dysfunction under obesity-induced metabolic stress.
    J Biol Chem. 2026;302:111164.
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    November 2025
  2. QI B, Chen Y, Lan Y, Lou Y, et al
    Metformin attenuates O-GlcNAc modification to improve renal function via AMPK/mTOR signaling in diabetic nephropathy.
    J Biol Chem. 2025 Nov 5:110909. doi: 10.1016/j.jbc.2025.110909.
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    October 2025
  3. ZHANG S, Hu X, Zhang B, Liu J, et al
    Mapping cellular cytosolic pH in vivo under physiological and pathophysiological conditions.
    J Biol Chem. 2025;301:110637.
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    September 2025
  4. GU J, Qi MX, Zhang RX, Song YY, et al
    Sidt2 inhibits islet beta-cell dedifferentiation by regulating insulin secretion.
    J Biol Chem. 2025;301:110544.
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    May 2025
  5. GUAN J, Shi X, Ma J, Yin Y, et al
    Circular RNA-OGDH Promotes PANoptosis in Diabetic Cardiomyopathy: A Novel Mechanistic Insight.
    J Biol Chem. 2025 May 22:110280. doi: 10.1016/j.jbc.2025.110280.
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  6. FANG J, Hu Z, Luo T, Chen S, et al
    beta-hydroxybutyrate serves as a regulator in ketone body metabolism through lysine beta-hydroxybutyrylation.
    J Biol Chem. 2025;301:108475.
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    March 2025
  7. JACOBS R, Herinckx G, Galland N, Balty C, et al
    Combined deletion of cytosolic 5'-nucleotidases IA and II lowers glycemia by improving skeletal muscle insulin action and lowering hepatic glucose production.
    J Biol Chem. 2025;301:108295.
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    January 2025
  8. SUNILKUMAR S, Yerlikaya EI, VanCleave A, Subrahmanian SM, et al
    REDD1-dependent GSK3beta signaling in podocytes promotes canonical NF-kappaB activation in diabetic nephropathy.
    J Biol Chem. 2025 Jan 27:108244. doi: 10.1016/j.jbc.2025.108244.
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  9. YOKOO T, Watanabe K, Iida K, Nakachi Y, et al
    Betagenin ameliorates diabetes by inducing insulin secretion and beta-cell proliferation.
    J Biol Chem. 2025 Jan 16:108202. doi: 10.1016/j.jbc.2025.108202.
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  10. SITTON J, Pickett D, Rodriguez A, Kurouski D, et al
    Lipids determine the toxicity of human islet polypeptide aggregates in vivo.
    J Biol Chem. 2025;301:108029.
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    December 2024
  11. YAO TF, Wang ZY, Sun L, Yu SX, et al
    DNMT3b-mediated CpA methylation facilitates REST binding and gene silencing and exacerbates hippocampal demyelination in diabetic mice.
    J Biol Chem. 2024 Dec 25:108137. doi: 10.1016/j.jbc.2024.108137.
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  12. HUANG Y, Zhang Y, Liu Y, Jin Y, et al
    PRDX4 mitigates diabetic retinopathy by inhibiting reactive gliosis, apoptosis, ER stress, oxidative stress, and mitochondrial dysfunction in Muller cells.
    J Biol Chem. 2024 Dec 18:108111. doi: 10.1016/j.jbc.2024.108111.
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  13. LI H, Lin L, Huang X, Lu Y, et al
    2-Hydroxylation is a chemical switch linking fatty acids to glucose-stimulated insulin secretion.
    J Biol Chem. 2024;300:107912.
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    September 2024
  14. COLLINS J, Piscopio RA, Reyland ME, Johansen CG, et al
    Cleavage of protein kinase c delta by caspase-3 mediates proinflammatory cytokine-induced apoptosis in pancreatic islets.
    J Biol Chem. 2024;300:107611.
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  15. TRAN MT, Lim JJ, Loh TJ, Mannering SI, et al
    A structural basis of T cell cross-reactivity to native and spliced self-antigens presented by HLA-DQ8.
    J Biol Chem. 2024;300:107612.
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    August 2024
  16. SHARMA R, Amdare NP, Ghosh A, Schloss J, et al
    Structural and biochemical analysis of highly similar HLA-B allotypes differentially associated with type 1 diabetes.
    J Biol Chem. 2024 Aug 20:107702. doi: 10.1016/j.jbc.2024.107702.
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    July 2024
  17. DING Z, Ge W, Xu X, Xu X, et al
    A crucial role of adenosine deaminase in regulating gluconeogenesis in mice.
    J Biol Chem. 2024;300:107425.
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    June 2024
  18. ZHANG B, Bu C, Wang Q, Chen Q, et al
    Low molecular weight heparin promotes the PPAR pathway by protecting the glycocalyx of cells to delay the progression of diabetic nephropathy.
    J Biol Chem. 2024 Jun 24:107493. doi: 10.1016/j.jbc.2024.107493.
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  19. YAMAGUCHI H, Matsumura T, Sugawa H, Niimi N, et al
    Glucoselysine, a unique advanced glycation end-product of the polyol pathway and its association with vascular complications in type 2 diabetes.
    J Biol Chem. 2024 Jun 13:107479. doi: 10.1016/j.jbc.2024.107479.
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  20. BREUNIG SL, Chapman AM, LeBon J, Quijano JC, et al
    4S-fluorination of ProB29 in insulin lispro slows fibril formation.
    J Biol Chem. 2024;300:107332.
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    March 2024
  21. LI L, Yao Y, Wang Y, Cao J, et al
    G protein-coupled estrogen receptor 1 ameliorates nonalcoholic steatohepatitis through targeting AMPK-dependent signaling.
    J Biol Chem. 2024;300:105661.
    >> Share


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