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Articles published in
Proc Natl Acad Sci U S A
    June 2021
  1. HOU T, Su W, Duncan MJ, Olga VA, et al
    Time-restricted feeding protects the blood pressure circadian rhythm in diabetic mice.
    Proc Natl Acad Sci U S A. 2021;118.
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    March 2021
  2. WANG MY, Dean ED, Quittner-Strom E, Zhu Y, et al
    Glucagon blockade restores functional beta-cell mass in type 1 diabetic mice and enhances function of human islets.
    Proc Natl Acad Sci U S A. 2021;118.
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    February 2021
  3. MITCHELL AM, Alkanani AA, McDaniel KA, Pyle L, et al
    T-cell responses to hybrid insulin peptides prior to type 1 diabetes development.
    Proc Natl Acad Sci U S A. 2021;118.
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  4. MUNOZ M, Hegazy AN, Brunner TM, Holecska V, et al
    Th2 cells lacking T-bet suppress naive and memory T cell responses via IL-10.
    Proc Natl Acad Sci U S A. 2021;118.
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    December 2020
  5. JAIN S, Pydi SP, Toti KS, Robaye B, et al
    Lack of adipocyte purinergic P2Y6 receptor greatly improves whole body glucose homeostasis.
    Proc Natl Acad Sci U S A. 2020;117:30763-30774.
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    November 2020
  6. WANG Z, Wang J, Li H, Yu J, et al
    Dual self-regulated delivery of insulin and glucagon by a hybrid patch.
    Proc Natl Acad Sci U S A. 2020;117:29512-29517.
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  7. REGE NK, Liu M, Yang Y, Dhayalan B, et al
    Evolution of insulin at the edge of foldability and its medical implications.
    Proc Natl Acad Sci U S A. 2020;117:29618-29628.
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  8. HU H, Zakharov PN, Peterson OJ, Unanue ER, et al
    Cytocidal macrophages in symbiosis with CD4 and CD8 T cells cause acute diabetes following checkpoint blockade of PD-1 in NOD mice.
    Proc Natl Acad Sci U S A. 2020 Nov 23. pii: 2019743117.
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  9. TANG S, Zhang M, Zeng S, Huang Y, et al
    Reversal of autoimmunity by mixed chimerism enables reactivation of beta cells and transdifferentiation of alpha cells in diabetic NOD mice.
    Proc Natl Acad Sci U S A. 2020 Nov 23. pii: 2012389117.
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  10. NIU J, Zhao J, Wu J, Qiao G, et al
    Curtailing FGF19's mitogenicity by suppressing its receptor dimerization ability.
    Proc Natl Acad Sci U S A. 2020;117:29025-29034.
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  11. SHENG X, Qiu C, Liu H, Gluck C, et al
    Systematic integrated analysis of genetic and epigenetic variation in diabetic kidney disease.
    Proc Natl Acad Sci U S A. 2020 Nov 3. pii: 2005905117.
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  12. OUYANG J, Ji X, Zhang X, Feng C, et al
    In situ sprayed NIR-responsive, analgesic black phosphorus-based gel for diabetic ulcer treatment.
    Proc Natl Acad Sci U S A. 2020 Nov 2. pii: 2016268117.
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    October 2020
  13. WANG B, Lin H, Li X, Lu W, et al
    The adaptor protein APPL2 controls glucose-stimulated insulin secretion via F-actin remodeling in pancreatic beta-cells.
    Proc Natl Acad Sci U S A. 2020 Oct 29. pii: 2016997117.
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    August 2020
  14. SATHKUMARA HD, Muruganandah V, Cooper MM, Field MA, et al
    Mucosal delivery of ESX-1-expressing BCG strains provides superior immunity against tuberculosis in murine type 2 diabetes.
    Proc Natl Acad Sci U S A. 2020 Aug 10. pii: 2003235117.
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    July 2020
  15. NGUYEN LD, Fischer TT, Abreu D, Arroyo A, et al
    Calpain inhibitor and ibudilast rescue beta cell functions in a cellular model of Wolfram syndrome.
    Proc Natl Acad Sci U S A. 2020;117:17389-17398.
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  16. LAY AC, Barrington AF, Hurcombe JA, Ramnath RD, et al
    A role for NPY-NPY2R signaling in albuminuric kidney disease.
    Proc Natl Acad Sci U S A. 2020;117:15862-15873.
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    June 2020
  17. BASU A, Gujral K
    Evidence generation, decision making, and consequent growth in health disparities.
    Proc Natl Acad Sci U S A. 2020;117:14042-14051.
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    May 2020
  18. ZHANG Z, Gallagher T, Scherer PE, Beutler B, et al
    Tissue-specific disruption of Kbtbd2 uncovers adipocyte-intrinsic and -extrinsic features of the teeny lipodystrophy syndrome.
    Proc Natl Acad Sci U S A. 2020;117:11829-11835.
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  19. PYTOWSKI L, Lee CF, Foley AC, Vaux DJ, et al
    Liquid-liquid phase separation of type II diabetes-associated IAPP initiates hydrogelation and aggregation.
    Proc Natl Acad Sci U S A. 2020 May 15. pii: 1916716117.
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  20. TAVALLAIE M, Voshtani R, Deng X, Qiao Y, et al
    Moderation of mitochondrial respiration mitigates metabolic syndrome of aging.
    Proc Natl Acad Sci U S A. 2020;117:9840-9850.
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    April 2020
  21. QADIR MMF, Alvarez-Cubela S, Klein D, van Dijk J, et al
    Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche.
    Proc Natl Acad Sci U S A. 2020 Apr 30. pii: 1918314117.
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  22. HUGHES JW, Cho JH, Conway HE, DiGruccio MR, et al
    Primary cilia control glucose homeostasis via islet paracrine interactions.
    Proc Natl Acad Sci U S A. 2020;117:8912-8923.
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  23. GONZALEZ-MORO I, Olazagoitia-Garmendia A, Colli ML, Cobo-Vuilleumier N, et al
    The T1D-associated lncRNA Lnc13 modulates human pancreatic beta cell inflammation by allele-specific stabilization of STAT1 mRNA.
    Proc Natl Acad Sci U S A. 2020 Apr 13. pii: 1914353117.
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    March 2020
  24. BASU S, Barad M, Yadav D, Nandy A, et al
    DBC1, p300, HDAC3, and Siah1 coordinately regulate ELL stability and function for expression of its target genes.
    Proc Natl Acad Sci U S A. 2020;117:6509-6520.
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  25. POLINA I, Jansen HJ, Li T, Moghtadaei M, et al
    Loss of insulin signaling may contribute to atrial fibrillation and atrial electrical remodeling in type 1 diabetes.
    Proc Natl Acad Sci U S A. 2020 Mar 20. pii: 1914853117.
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    January 2020
  26. PETRENKO V, Gandasi NR, Sage D, Tengholm A, et al
    In pancreatic islets from type 2 diabetes patients, the dampened circadian oscillators lead to reduced insulin and glucagon exocytosis.
    Proc Natl Acad Sci U S A. 2020 Jan 21. pii: 1916539117.
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  27. YU J, Shi Y, Zhao K, Yang G, et al
    Enhanced expression of beta cell CaV3.1 channels impairs insulin release and glucose homeostasis.
    Proc Natl Acad Sci U S A. 2020;117:448-453.
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    December 2019
  28. SHI Y, Park KS, Kim SH, Yu J, et al
    IgGs from patients with amyotrophic lateral sclerosis and diabetes target CaValpha2delta1 subunits impairing islet cell function and survival.
    Proc Natl Acad Sci U S A. 2019 Dec 11. pii: 1911956116.
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    November 2019
  29. WANG X, Lu J, Xie W, Lu X, et al
    Maternal diabetes induces autism-like behavior by hyperglycemia-mediated persistent oxidative stress and suppression of superoxide dismutase 2.
    Proc Natl Acad Sci U S A. 2019 Nov 4. pii: 1912625116.
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    September 2019
  30. KUO T, Kraakman MJ, Damle M, Gill R, et al
    Identification of C2CD4A as a human diabetes susceptibility gene with a role in beta cell insulin secretion.
    Proc Natl Acad Sci U S A. 2019 Sep 16. pii: 1904311116.
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  31. WILSON PC, Wu H, Kirita Y, Uchimura K, et al
    The single-cell transcriptomic landscape of early human diabetic nephropathy.
    Proc Natl Acad Sci U S A. 2019 Sep 10. pii: 1908706116.
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    July 2019
  32. PETERS A, Wekerle H
    Autoimmune diabetes mellitus and the leaky gut.
    Proc Natl Acad Sci U S A. 2019 Jul 9. pii: 1909224116.
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    June 2019
  33. SORINI C, Cosorich I, Lo Conte M, De Giorgi L, et al
    Loss of gut barrier integrity triggers activation of islet-reactive T cells and autoimmune diabetes.
    Proc Natl Acad Sci U S A. 2019 Jun 10. pii: 1814558116.
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    March 2019
  34. LIU C, Ge HM, Liu BH, Dong R, et al
    Targeting pericyte-endothelial cell crosstalk by circular RNA-cPWWP2A inhibition aggravates diabetes-induced microvascular dysfunction.
    Proc Natl Acad Sci U S A. 2019 Mar 26. pii: 1814874116.
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  35. GAO P, Uzun Y, He B, Salamati SE, et al
    Risk variants disrupting enhancers of TH1 and TREG cells in type 1 diabetes.
    Proc Natl Acad Sci U S A. 2019 Mar 25. pii: 1815336116.
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  36. YU M, Song W, Tian F, Dai Z, et al
    Temperature- and rigidity-mediated rapid transport of lipid nanovesicles in hydrogels.
    Proc Natl Acad Sci U S A. 2019;116:5362-5369.
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  37. ZHENG X, Narayanan S, Sunkari VG, Eliasson S, et al
    Triggering of a Dll4-Notch1 loop impairs wound healing in diabetes.
    Proc Natl Acad Sci U S A. 2019 Mar 18. pii: 1900351116.
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    February 2019
  38. MILOUDI K, Oubaha M, Menard C, Dejda A, et al
    NOTCH1 signaling induces pathological vascular permeability in diabetic retinopathy.
    Proc Natl Acad Sci U S A. 2019 Feb 20. pii: 1814711116.
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    November 2018

  39. Correction for Zhao et al., Intestinal virome changes precede autoimmunity in type I diabetes-susceptible children.
    Proc Natl Acad Sci U S A. 2018 Nov 19. pii: 1817913115.
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    October 2018
  40. RASH BG, Micali N, Huttner AJ, Morozov YM, et al
    Metabolic regulation and glucose sensitivity of cortical radial glial cells.
    Proc Natl Acad Sci U S A. 2018;115:10142-10147.
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  41. SO M, Elso CM, Tresoldi E, Pakusch M, et al
    Proinsulin C-peptide is an autoantigen in people with type 1 diabetes.
    Proc Natl Acad Sci U S A. 2018 Oct 1. pii: 1809208115.
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    September 2018
  42. GASSAWAY BM, Petersen MC, Surovtseva YV, Barber KW, et al
    PKCepsilon contributes to lipid-induced insulin resistance through cross talk with p70S6K and through previously unknown regulators of insulin signaling.
    Proc Natl Acad Sci U S A. 2018;115:E8996-E9005.
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  43. SHEHATA HM, Khan S, Chen E, Fields PE, et al
    Lack of Sprouty 1 and 2 enhances survival of effector CD8(+) T cells and yields more protective memory cells.
    Proc Natl Acad Sci U S A. 2018;115:E8939-E8947.
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    August 2018
  44. KLEINER S, Gomez D, Megra B, Na E, et al
    Mice harboring the human SLC30A8 R138X loss-of-function mutation have increased insulin secretory capacity.
    Proc Natl Acad Sci U S A. 2018;115:E7642-E7649.
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    July 2018
  45. KIM S, Maynard JC, Strickland A, Burlingame AL, et al
    Schwann cell O-GlcNAcylation promotes peripheral nerve remyelination via attenuation of the AP-1 transcription factor JUN.
    Proc Natl Acad Sci U S A. 2018;115:8019-8024.
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  46. WEFERS J, van Moorsel D, Hansen J, Connell NJ, et al
    Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle.
    Proc Natl Acad Sci U S A. 2018;115:7789-7794.
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  47. ZHANG H, Liu J, Qu D, Wang L, et al
    Serum exosomes mediate delivery of arginase 1 as a novel mechanism for endothelial dysfunction in diabetes.
    Proc Natl Acad Sci U S A. 2018 Jul 2. pii: 1721521115.
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    June 2018
  48. ZHU Y, Cankova Z, Iwanaszko M, Lichtor S, et al
    Potent laminin-inspired antioxidant regenerative dressing accelerates wound healing in diabetes.
    Proc Natl Acad Sci U S A. 2018 Jun 11. pii: 1804262115.
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    May 2018

  49. Correction for Spence et al., Revealing the specificity of regulatory T cells in murine autoimmune diabetes.
    Proc Natl Acad Sci U S A. 2018 May 29. pii: 1808331115.
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  50. BAR L, Feger M, Fajol A, Klotz LO, et al
    Insulin suppresses the production of fibroblast growth factor 23 (FGF23).
    Proc Natl Acad Sci U S A. 2018;115:5804-5809.
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    April 2018
  51. JIAN X, Felsenfeld G
    Insulin promoter in human pancreatic beta cells contacts diabetes susceptibility loci and regulates genes affecting insulin metabolism.
    Proc Natl Acad Sci U S A. 2018 Apr 30. pii: 1803146115.
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  52. SPENCE A, Purtha W, Tam J, Dong S, et al
    Revealing the specificity of regulatory T cells in murine autoimmune diabetes.
    Proc Natl Acad Sci U S A. 2018 Apr 30. pii: 1715590115.
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    March 2018
  53. ZHANG M, Racine JJ, Lin Q, Liu Y, et al
    MHC-mismatched mixed chimerism restores peripheral tolerance of noncross-reactive autoreactive T cells in NOD mice.
    Proc Natl Acad Sci U S A. 2018;115:E2329-E2337.
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    January 2018
  54. IACOVAZZO D, Flanagan SE, Walker E, Quezado R, et al
    MAFA missense mutation causes familial insulinomatosis and diabetes mellitus.
    Proc Natl Acad Sci U S A. 2018 Jan 16. pii: 1712262115.
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    December 2017
  55. AN D, Chiu A, Flanders JA, Song W, et al
    Designing a retrievable and scalable cell encapsulation device for potential treatment of type 1 diabetes.
    Proc Natl Acad Sci U S A. 2017 Dec 26. pii: 1708806115.
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  56. JUN G, Manning A, Almeida M, Zawistowski M, et al
    Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees.
    Proc Natl Acad Sci U S A. 2017 Dec 26. pii: 1705859115.
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  57. WANG Y, Sosinowski T, Novikov A, Crawford F, et al
    C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.
    Proc Natl Acad Sci U S A. 2017 Dec 18. pii: 1716527115.
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    November 2017
  58. THOUNAOJAM MC, Powell FL, Patel S, Gutsaeva DR, et al
    Protective effects of agonists of growth hormone-releasing hormone (GHRH) in early experimental diabetic retinopathy.
    Proc Natl Acad Sci U S A. 2017 Nov 27. pii: 1718592114.
    >> Share

  59. CARRERO JA, McCarthy DP, Ferris ST, Wan X, et al
    Resident macrophages of pancreatic islets have a seminal role in the initiation of autoimmune diabetes of NOD mice.
    Proc Natl Acad Sci U S A. 2017 Nov 13. pii: 201713543.
    >> Share

    October 2017
  60. LUDWIG B, Ludwig S, Steffen A, Knauf Y, et al
    Favorable outcome of experimental islet xenotransplantation without immunosuppression in a nonhuman primate model of diabetes.
    Proc Natl Acad Sci U S A. 2017;114:11745-11750.
    >> Share

  61. ZENG D
    Bridge between type 1 diabetes in mouse and man.
    Proc Natl Acad Sci U S A. 2017 Oct 2. pii: 201715058.
    >> Share

  62. RIBEIRO D, Horvath I, Heath N, Hicks R, et al
    Extracellular vesicles from human pancreatic islets suppress human islet amyloid polypeptide amyloid formation.
    Proc Natl Acad Sci U S A. 2017 Oct 2. pii: 201711389.
    >> Share

    September 2017
  63. YU H, Gagliani N, Ishigame H, Huber S, et al
    Intestinal type 1 regulatory T cells migrate to periphery to suppress diabetogenic T cells and prevent diabetes development.
    Proc Natl Acad Sci U S A. 2017 Sep 11. pii: 201705599.
    >> Share


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