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Articles published in
Am J Psychiatry
    July 2026
  1. VAN DER MEER D, Shadrin AA, Stinson SE, Koch E, et al
    Divergent Patterns of Genetic Overlap Between Severe Mental Disorders and Metabolic Markers.
    Am J Psychiatry. 2026;183:482-493.
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    June 2026
  2. KALIN NH
    Treating Severe Depression and Suicidality.
    Am J Psychiatry. 2026;183:367-369.
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  3. KELLNER CH, Jelovac A, Braithwaite R
    Relapse Prevention After Successful ECT for Depression: The Role of Lithium and Continuation/Maintenance ECT.
    Am J Psychiatry. 2026;183:370-372.
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  4. TUCCIARONE JM, Bandeira ID, Blasey C, Kratter IH, et al
    Low-Dose Buprenorphine Following Ketamine Treatment for Suicidal Ideation in Major Depressive Disorder: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Am J Psychiatry. 2026;183:409-419.
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  5. JELEN LA, O'Daly O, Zelaya FO, Stone JM, et al
    Regional Blood Flow Signatures of Opioidergic Modulation of Ketamine in Major Depressive Disorder: A Randomized Crossover Study.
    Am J Psychiatry. 2026;183:420-430.
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  6. ROVERS JJE, van Eijndhoven PFP, Abbot C, Argyelan M, et al
    A Global Delphi-Based Expert Consensus on Relapse Prevention Strategies Following Successful Electroconvulsive Therapy for Major Depressive Disorder.
    Am J Psychiatry. 2026;183:401-408.
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    May 2026
  7. BLUMBERGER DM, Vila Rodriguez F, McClintock SM, Thorpe KE, et al
    Clinical and Cognitive Outcomes Comparing Right Unilateral Ultrabrief Electroconvulsive Therapy Versus Magnetic Seizure Therapy for Bipolar Depression: The CORRECT-BD Trial.
    Am J Psychiatry. 2026 May 6:appiajp20250955. doi: 10.1176/appi.ajp.20250955.
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    March 2026
  8. VALIENGO LDCL, Pinto BS, Luethi M, Afonso Santos L, et al
    Bilateral Theta-Burst Stimulation of Dorsolateral Prefrontal Cortex Regions for Late-Life Depression: A Randomized, Sham-Controlled Clinical Trial.
    Am J Psychiatry. 2026 Mar 11:appiajp20250537. doi: 10.1176/appi.ajp.20250537.
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    January 2026
  9. BLOCH MH, Dwyer JB
    Potentially Problematic Research Practices in a Study on Ketamine for Pediatric Depression: Response to Ploderl and Moncrieff.
    Am J Psychiatry. 2026;183:83-85.
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  10. PLODERL M, Moncrieff J
    Potentially Problematic Research Practices in a Study on Ketamine for Pediatric Depression.
    Am J Psychiatry. 2026;183:82-83.
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  11. KALIN NH
    Externalizing Disorders, Pediatric Anxiety, Autism, and Inflammation-Related Depression.
    Am J Psychiatry. 2026;183:1-3.
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  12. MAC GIOLLABHUI N, Madison AA, Lydston M, Lenoel Quang E, et al
    Effect of Anti-Inflammatory Treatment on Depressive Symptom Severity and Anhedonia in Depressed Individuals With Elevated Inflammation: Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Am J Psychiatry. 2026;183:70-79.
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    December 2025
  13. KALIN NH
    Updates and Advances in the Treatment of Substance Use Disorders, Depression, and Borderline Personality Disorder.
    Am J Psychiatry. 2025;182:1029-1031.
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  14. DURGAM S, Earley WR, Kozauer SG, Mo Y, et al
    Adjunctive Lumateperone in Patients With Major Depressive Disorder: Results From a Randomized, Double-Blind, Phase 3 Trial.
    Am J Psychiatry. 2025;182:1072-1082.
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  15. BRODSKY BS, Galfalvy H, Mann JJ, Grunebaum MF, et al
    Dialectical Behavior Therapy Versus Serotonin Reuptake Inhibitor Treatment for Suicidal Behavior in Borderline Personality Disorder: A Randomized Controlled Trial.
    Am J Psychiatry. 2025;182:1083-1092.
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    October 2025
  16. KALIN NH
    Adolescent Suicidality and Depression, Premenstrual Dysphoric Disorder, and Safety Issues Related to Ketamine and Esketamine Treatment.
    Am J Psychiatry. 2025;182:889-891.
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  17. WEI SM, Wakim P, Martinez PE, Nieman LK, et al
    Differential Effects of Ovarian Steroids in Women With and Without Premenstrual Dysphoric Disorder: A Replication and Extension of Findings.
    Am J Psychiatry. 2025;182:922-934.
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  18. FOUNTOULAKIS KN, Saitis A, Schatzberg AF
    Esketamine Treatment for Depression in Adults: Response to Price et al. and Canuso et al.
    Am J Psychiatry. 2025;182:954-956.
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  19. CANUSO CM, Bossie C, Fu DJ, Lane R, et al
    Comment on Esketamine Treatment for Depression in Adults: A PRISMA Systematic Review and Meta-Analysis.
    Am J Psychiatry. 2025;182:951-954.
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  20. WHITTLE S, Rakesh D, Simmons JG, Schwartz O, et al
    Prospective Associations Between Structural Brain Development and Onset of Depressive Disorder During Adolescence and Emerging Adulthood.
    Am J Psychiatry. 2025;182:935-944.
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    September 2025
  21. LI SW, Kumpf KT, Urrutia J, Krystal JH, et al
    Ketamine for Depression, but at What Cost? A Review of Ketamine's Neurotoxic Effects From Preclinical and Human Studies.
    Am J Psychiatry. 2025 Sep 10:appiajp20250276. doi: 10.1176/appi.ajp.20250276.
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    July 2025
  22. AHN Y, Kim J, Jung K, Lee DJ, et al
    Relationship Between Problematic Alcohol Use and Various Psychiatric Disorders: A Genetically Informed Study.
    Am J Psychiatry. 2025;182:671-682.
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    June 2025
  23. FONZO GA, Doss MK, Nemeroff CB
    There's More Than One Way to Bring Health Back: Divergent Effects of Psilocybin and Escitalopram Treatment on Emotional Brain Function in Depression.
    Am J Psychiatry. 2025;182:512-515.
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  24. KALIN NH
    Depression, Inflammation, and Postpartum Psychosis.
    Am J Psychiatry. 2025;182:501-503.
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  25. SAVITZ J, Figueroa-Hall LK, Teague TK, Yeh HW, et al
    Systemic Inflammation and Anhedonic Responses to an Inflammatory Challenge in Adults With Major Depressive Disorder: A Randomized Controlled Trial.
    Am J Psychiatry. 2025;182:560-568.
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    May 2025
  26. CLAPP MA, Castro VM, Verhaak P, McCoy TH, et al
    Stratifying Risk for Postpartum Depression at Time of Hospital Discharge.
    Am J Psychiatry. 2025 May 19:appiajp20240381. doi: 10.1176/appi.ajp.20240381.
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  27. MILLER AH
    Advancing an Inflammatory Subtype of Major Depression.
    Am J Psychiatry. 2025 May 7:appiajp20250289. doi: 10.1176/appi.ajp.20250289.
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  28. WALL MB, Demetriou L, Giribaldi B, Roseman L, et al
    Reduced Brain Responsiveness to Emotional Stimuli With Escitalopram But Not Psilocybin Therapy for Depression.
    Am J Psychiatry. 2025 May 7:appiajp20230751. doi: 10.1176/appi.ajp.20230751.
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  29. RUGGIERO KJ, Andrews A, Davidson TM, Gavrilova Y, et al
    Randomized Controlled Trial of "Bounce Back Now," a Mobile App to Reduce Post-Disaster Symptoms of Posttraumatic Stress, Depressed Mood, and Sleep Disturbance.
    Am J Psychiatry. 2025;182:463-472.
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  30. TANG VM, Aaronson S, Abdelghani M, Baeken C, et al
    Assessment and Management of Concurrent Substance Use in Patients Receiving Repetitive Transcranial Magnetic Stimulation for Depressive, Obsessive-Compulsive, Psychotic, and Trauma-Related Disorders: A Delphi Consensus Study and Guideline.
    Am J Psychiatry. 2025;182:438-451.
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    April 2025
  31. CHEN L, Fukuda AM, Jiang S, Leuchter MK, et al
    Treating Depression With Repetitive Transcranial Magnetic Stimulation: A Clinician's Guide.
    Am J Psychiatry. 2025 Apr 30:appiajp20240859. doi: 10.1176/appi.ajp.20240859.
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    March 2025
  32. KALIN NH
    New Developments in the Treatment of Depression, OCD, and Schizophrenia.
    Am J Psychiatry. 2025;182:223-226.
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  33. MATHEW SJ, Murphy N
    Six Years After Approval of Esketamine Nasal Spray for Serious Depression: Clinical Conundrums and Unanswered Questions.
    Am J Psychiatry. 2025;182:227-230.
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  34. BRUNONI AR, Padberg F
    Spaced Transcranial Direct Current Stimulation for Depression: The Road Less Traveled.
    Am J Psychiatry. 2025;182:231-233.
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    February 2025
  35. KING AC, Fischer AM, Cursio JF, Didier NA, et al
    Real-Time Assessment of Alcohol Reward, Stimulation, and Negative Affect in Individuals With and Without Alcohol Use Disorder and Depressive Disorders.
    Am J Psychiatry. 2025;182:187-197.
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  36. KYPRIOTAKIS G, Cinciripini PM, Green CE, Lawrence D, et al
    Effects of Varenicline, Bupropion, Nicotine Patch, and Placebo on Treating Smoking Among Persons With Current or Past Major Depressive Disorder: Secondary Analysis of a Double-Blind, Randomized, Placebo-Controlled Trial.
    Am J Psychiatry. 2025;182:174-186.
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    January 2025
  37. FOUNTOULAKIS KN, Saitis A, Schatzberg AF
    Esketamine Treatment for Depression in Adults: A PRISMA Systematic Review and Meta-Analysis.
    Am J Psychiatry. 2025 Jan 29:appiajp20240515. doi: 10.1176/appi.ajp.20240515.
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  38. COUTURE M, Desbeaumes Jodoin V, Bousseau E, Sarshoghi A, et al
    Spaced Transcranial Direct Current Stimulation for Major Depression.
    Am J Psychiatry. 2025 Jan 29:appiajp20240083. doi: 10.1176/appi.ajp.20240083.
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  39. MCINTYRE RS, Kwan ATH, Mansur RB, Oliveira-Maia AJ, et al
    Psychedelics for the Treatment of Psychiatric Disorders: Interpreting and Translating Available Evidence and Guidance for Future Research.
    Am J Psychiatry. 2025;182:21-32.
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  40. AARONSON ST, van der Vaart A, Miller T, LaPratt J, et al
    Single-Dose Psilocybin for Depression With Severe Treatment Resistance: An Open-Label Trial.
    Am J Psychiatry. 2025;182:104-113.
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  41. RAMAEKERS JG, Reckweg JT, Mason NL
    Benefits and Challenges of Ultra-Fast, Short-Acting Psychedelics in the Treatment of Depression.
    Am J Psychiatry. 2025;182:33-46.
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  42. FONZO GA, Wolfgang AS, Barksdale BR, Krystal JH, et al
    Psilocybin: From Psychiatric Pariah to Perceived Panacea.
    Am J Psychiatry. 2025;182:54-78.
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  43. KIRLIC N, Lennard-Jones M, Atli M, Malievskaia E, et al
    Compass Psychological Support Model for COMP360 Psilocybin Treatment of Serious Mental Health Conditions.
    Am J Psychiatry. 2025;182:126-132.
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    December 2024
  44. WIDOM CS, Courtney K, Do HH
    Pathways to Homelessness: Childhood Maltreatment and Psychiatric Symptoms Increase Risk of Homelessness.
    Am J Psychiatry. 2024;181:1103-1111.
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  45. GREY DK, Purcell JB, Buford KN, Schuster MA, et al
    Discrimination Exposure, Neural Reactivity to Stress, and Psychological Distress.
    Am J Psychiatry. 2024;181:1112-1126.
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    October 2024
  46. GALLUCCI J, Yu JC, Oliver LD, Nakua H, et al
    Neural Circuitry and Therapeutic Targeting of Depressive Symptoms in Schizophrenia Spectrum Disorders.
    Am J Psychiatry. 2024;181:910-919.
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  47. HWANG M, Brady R
    Neural Circuitry and Therapeutic Targeting of Depressive Symptoms in Schizophrenia Spectrum Disorders.
    Am J Psychiatry. 2024;181:858-860.
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    September 2024
  48. SOARES CN
    Contraception, Intrauterine Systems, and Depression: Can We Spot the Real Perpetrator?
    Am J Psychiatry. 2024;181:789-792.
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  49. MARTIN DM, Nikolin S
    "Closing the Loop" With Transcranial Electrical Stimulation for Depression.
    Am J Psychiatry. 2024;181:793-794.
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  50. KASTER TS, Blumberger DM
    Positioning rTMS Within a Sequential Treatment Algorithm of Depression.
    Am J Psychiatry. 2024;181:781-783.
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  51. KALIN NH
    Depression: Factors Contributing to Risk and Therapeutic Insights.
    Am J Psychiatry. 2024;181:777-780.
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  52. DALHUISEN I, van Oostrom I, Spijker J, Wijnen B, et al
    rTMS as a Next Step in Antidepressant Nonresponders: A Randomized Comparison With Current Antidepressant Treatment Approaches.
    Am J Psychiatry. 2024;181:806-814.
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  53. SCHWIPPEL T, Pupillo F, Feldman Z, Walker C, et al
    Closed-Loop Transcranial Alternating Current Stimulation for the Treatment of Major Depressive Disorder: An Open-Label Pilot Study.
    Am J Psychiatry. 2024;181:842-845.
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  54. HESS EM, Greenstein DK, Hutchinson OL, Zarate CA, et al
    Entactogen Effects of Ketamine: A Reverse-Translational Study.
    Am J Psychiatry. 2024;181:815-823.
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    August 2024
  55. SALVATORE JE, Ohlsson H, Sundquist J, Sundquist K, et al
    Peer Social Genetic Effects and the Etiology of Substance Use Disorders, Major Depression, and Anxiety Disorder in a Swedish National Sample.
    Am J Psychiatry. 2024 Aug 7:appiajp20230358. doi: 10.1176/appi.ajp.20230358.
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    July 2024
  56. LARSEN SV, Mikkelsen AP, Ozenne B, Munk-Olsen T, et al
    Association Between Intrauterine System Hormone Dosage and Depression Risk.
    Am J Psychiatry. 2024 Jul 10:appiajp20230909. doi: 10.1176/appi.ajp.20230909.
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  57. POLIMANTI R
    Using Medical Records to Investigate the Genetics of Treatment-Resistant Depression Across Health Care Systems.
    Am J Psychiatry. 2024;181:569-571.
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  58. AKIKI TJ, Abdallah CG
    Mapping the Depressed Brain Under Stress Using Multimodal Neuroimaging.
    Am J Psychiatry. 2024;181:578-580.
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  59. ROHDE C, Ostergaard SD, Jefsen OH
    A Nationwide Target Trial Emulation Assessing the Risk of Antidepressant-Induced Mania Among Patients With Bipolar Depression.
    Am J Psychiatry. 2024;181:630-638.
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  60. JONSSON L, Horbeck E, Primerano A, Song J, et al
    Association of Occupational Dysfunction and Hospital Admissions With Different Polygenic Profiles in Bipolar Disorder.
    Am J Psychiatry. 2024;181:620-629.
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    May 2024
  61. KANG J, Castro VM, Ripperger M, Venkatesh S, et al
    Genome-Wide Association Study of Treatment-Resistant Depression: Shared Biology With Metabolic Traits.
    Am J Psychiatry. 2024 May 15:appiajp20230247. doi: 10.1176/appi.ajp.20230247.
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    April 2024
  62. BAUM ML, Widge AS, Carpenter LL, McDonald WM, et al
    Pharmacogenomic Clinical Support Tools for the Treatment of Depression.
    Am J Psychiatry. 2024 Apr 30:appiajp20230657. doi: 10.1176/appi.ajp.20230657.
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  63. IRONSIDE M, Duda JM, Moser AD, Holsen LM, et al
    Association of Lower Rostral Anterior Cingulate GABA+ and Dysregulated Cortisol Stress Response With Altered Functional Connectivity in Young Adults With Lifetime Depression: A Multimodal Imaging Investigation of Trait and State Effects.
    Am J Psychiatry. 2024 Apr 30:appiajp20230382. doi: 10.1176/appi.ajp.20230382.
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  64. KAVIRAJAN H
    Neglect of Adverse Effects in Treatment Guidelines for Depression.
    Am J Psychiatry. 2024;181:342-345.
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    March 2024
  65. STEFFENS DC
    Late-Life Depression, Antidepressant Treatment, and Cognition: The Short Haul and the Long Haul.
    Am J Psychiatry. 2024;181:183-185.
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  66. PHILLIPS ML
    Multimodal Predictors of Treatment Response in Major Depressive Disorder: Advancing Personalized Medicine in Psychiatry.
    Am J Psychiatry. 2024;181:180-182.
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  67. POIROT MG, Ruhe HG, Mutsaerts HMM, Maximov II, et al
    Treatment Response Prediction in Major Depressive Disorder Using Multimodal MRI and Clinical Data: Secondary Analysis of a Randomized Clinical Trial.
    Am J Psychiatry. 2024;181:223-233.
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    February 2024
  68. AINSWORTH NJ, Marawi T, Maslej MM, Blumberger DM, et al
    Cognitive Outcomes After Antidepressant Pharmacotherapy for Late-Life Depression: A Systematic Review and Meta-Analysis.
    Am J Psychiatry. 2024 Feb 7:appiajp20230392. doi: 10.1176/appi.ajp.20230392.
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    January 2024
  69. KALIN NH
    Improving Clinical Outcomes and Informing New Interventions.
    Am J Psychiatry. 2024;181:1-3.
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  70. WALASZEK A
    Optimizing the Treatment of Late-Life Depression.
    Am J Psychiatry. 2024;181:7-10.
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  71. RUBINOW DR
    Suicide and the Menstrual Cycle.
    Am J Psychiatry. 2024;181:11-13.
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  72. BATAIL JV, Feyder MT, Bentzley BS, Williams NR, et al
    An Avenue for Optimization of Theta Burst Stimulation Protocols? Comments on the FOUR-D Randomized Noninferiority Clinical Trial.
    Am J Psychiatry. 2024;181:68-70.
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    December 2023
  73. KALIN NH
    Adversity and Resilience, Postpartum Depression, Suicide, and Racial/Ethnic Disparities.
    Am J Psychiatry. 2023;180:859-861.
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  74. ADAMS JAM, Chandra P, Mehta D
    The First Large GWAS Meta-Analysis for Postpartum Depression.
    Am J Psychiatry. 2023;180:862-864.
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  75. STOWE ZN
    Perinatal Mental Health: Advances and Opportunities.
    Am J Psychiatry. 2023;180:874-877.
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    October 2023
  76. GUINTIVANO J, Byrne EM, Kiewa J, Yao S, et al
    Meta-Analyses of Genome-Wide Association Studies for Postpartum Depression.
    Am J Psychiatry. 2023 Oct 18:appiajp20230053. doi: 10.1176/appi.ajp.20230053.
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  77. ISHTIAK-AHMED K, Musliner KL, Christensen KS, Mortensen EL, et al
    Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark.
    Am J Psychiatry. 2023 Oct 18:appiajp20230356. doi: 10.1176/appi.ajp.20230356.
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  78. SHACKMAN AJ, Gee DG
    Maternal Perinatal Stress Associated With Offspring Negative Emotionality, But the Underlying Mechanisms Remain Elusive.
    Am J Psychiatry. 2023;180:708-711.
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  79. KALIN NH
    Stress, Heritability, and Genetic Factors Influencing Depression, PTSD, and Suicidal Behavior.
    Am J Psychiatry. 2023;180:699-702.
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  80. LYNALL ME, McIntosh AM
    The Heterogeneity of Depression.
    Am J Psychiatry. 2023;180:703-704.
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  81. NGUYEN TD, Kowalec K, Pasman J, Larsson H, et al
    Genetic Contribution to the Heterogeneity of Major Depressive Disorder: Evidence From a Sibling-Based Design Using Swedish National Registers.
    Am J Psychiatry. 2023;180:714-722.
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  82. FARHAT LC, Blakey R, Davey Smith G, Fujita A, et al
    Networks of Neurodevelopmental Traits, Socioenvironmental Factors, Emotional Dysregulation in Childhood, and Depressive Symptoms Across Development in Two U.K. Cohorts.
    Am J Psychiatry. 2023;180:755-765.
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  83. CHATZINAKOS C, Pernia CD, Morrison FG, Iatrou A, et al
    Single-Nucleus Transcriptome Profiling of Dorsolateral Prefrontal Cortex: Mechanistic Roles for Neuronal Gene Expression, Including the 17q21.31 Locus, in PTSD Stress Response.
    Am J Psychiatry. 2023;180:739-754.
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  84. DOCHERTY AR, Mullins N, Ashley-Koch AE, Qin X, et al
    GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors.
    Am J Psychiatry. 2023;180:723-738.
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    September 2023
  85. PINE DS
    Zuranolone Treatment for Depression: Steady Progress in Mechanism-Focused Therapeutics?
    Am J Psychiatry. 2023;180:631-633.
    >> Share

  86. KALIN NH
    Seeking New Solutions Addressing Structural Racism, Childhood Trauma, Suicidal Behaviors Across Sexual Orientations, and Postpartum Depression.
    Am J Psychiatry. 2023;180:625-628.
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  87. CLAYTON AH, Lasser R, Parikh SV, Iosifescu DV, et al
    Zuranolone for the Treatment of Adults With Major Depressive Disorder: A Randomized, Placebo-Controlled Phase 3 Trial.
    Am J Psychiatry. 2023;180:676-684.
    >> Share

    July 2023
  88. DELIGIANNIDIS KM, Meltzer-Brody S, Maximos B, Peeper EQ, et al
    Zuranolone for the Treatment of Postpartum Depression.
    Am J Psychiatry. 2023 Jul 26:appiajp20220785. doi: 10.1176/appi.ajp.20220785.
    >> Share

  89. JESTER DJ, Kohn JN, Tibirica L, Thomas ML, et al
    Differences in Social Determinants of Health Underlie Racial/Ethnic Disparities in Psychological Health and Well-Being: Study of 11,143 Older Adults.
    Am J Psychiatry. 2023;180:483-494.
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    April 2023
  90. BIERNACKA JM
    Do Polygenic Scores Inform Psychiatric Disease Risk After Considering Family History?
    Am J Psychiatry. 2023;180:256-258.
    >> Share

    March 2023
  91. ELBAU IG, Lynch CJ, Downar J, Vila-Rodriguez F, et al
    Functional Connectivity Mapping for rTMS Target Selection in Depression.
    Am J Psychiatry. 2023;180:230-240.
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  92. THASE ME
    A New Option for Depressed Patients Who Do Not Respond to Antidepressant Medications.
    Am J Psychiatry. 2023;180:188-189.
    >> Share

  93. KALIN NH
    Insights and Advances Into Treatments for Major Depression.
    Am J Psychiatry. 2023;180:173-176.
    >> Share

  94. JHA MK, Mathew SJ
    Pharmacotherapies for Treatment-Resistant Depression: How Antipsychotics Fit in the Rapidly Evolving Therapeutic Landscape.
    Am J Psychiatry. 2023;180:190-199.
    >> Share

  95. NUNES EV
    Alcohol and the Etiology of Depression.
    Am J Psychiatry. 2023;180:179-181.
    >> Share

  96. SACHS GS, Yeung PP, Rekeda L, Khan A, et al
    Adjunctive Cariprazine for the Treatment of Patients With Major Depressive Disorder: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study.
    Am J Psychiatry. 2023;180:241-251.
    >> Share

  97. DUNLOP BW, Cha J, Choi KS, Rajendra JK, et al
    Shared and Unique Changes in Brain Connectivity Among Depressed Patients After Remission With Pharmacotherapy Versus Psychotherapy.
    Am J Psychiatry. 2023;180:218-229.
    >> Share

  98. HASSERIS S, Albinana C, Vilhjalmsson BJ, Mortensen PB, et al
    Polygenic Risk and Episode Polarity Among Individuals With Bipolar Disorder.
    Am J Psychiatry. 2023;180:200-208.
    >> Share


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