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Articles published in
Proc Natl Acad Sci U S A
    November 2024
  1. DONG X, Sun F, Secaira-Morocho H, Hui A, et al
    The dichotomous roles of microbial-modified bile acids 7-oxo-DCA and isoDCA in intestinal tumorigenesis.
    Proc Natl Acad Sci U S A. 2024;121:e2317596121.
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  2. LI M, Chen X, Qu P, Shao Z, et al
    FBXO22 inhibits colitis and colorectal carcinogenesis by regulating the degradation of the S2448-phosphorylated form of mTOR.
    Proc Natl Acad Sci U S A. 2024;121:e2402035121.
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    October 2024
  3. ZHU Q, Li J, Sun H, Fan Z, et al
    O-GlcNAcylation of enolase 1 serves as a dual regulator of aerobic glycolysis and immune evasion in colorectal cancer.
    Proc Natl Acad Sci U S A. 2024;121:e2408354121.
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  4. ABDULLAYEVA G, Liu H, Liu TC, Simmons A, et al
    Goblet cell differentiation subgroups in colorectal cancer.
    Proc Natl Acad Sci U S A. 2024;121:e2414213121.
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  5. YE WL, Huang L, Yang XQ, Wan S, et al
    TRIM21 induces selective autophagic degradation of c-Myc and sensitizes regorafenib therapy in colorectal cancer.
    Proc Natl Acad Sci U S A. 2024;121:e2406936121.
    >> Share

  6. FAN L, Liu B, Wang Y, Tang B, et al
    Intestinal Lactobacillus murinus-derived small RNAs target porcine polyamine metabolism.
    Proc Natl Acad Sci U S A. 2024;121:e2413241121.
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    September 2024
  7. ZHANG N, Zhang R, Jiang L, Gao Z, et al
    Inhibition of colorectal cancer in Alzheimer's disease is mediated by gut microbiota via induction of inflammatory tolerance.
    Proc Natl Acad Sci U S A. 2024;121:e2314337121.
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    August 2024
  8. ZINK A, Obermeyer Z, Pierson E
    Race adjustments in clinical algorithms can help correct for racial disparities in data quality.
    Proc Natl Acad Sci U S A. 2024;121:e2402267121.
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    July 2024
  9. BORTEL P, Hagn G, Skos L, Bileck A, et al
    Memory effects of prior subculture may impact the quality of multiomic perturbation profiles.
    Proc Natl Acad Sci U S A. 2024;121:e2313851121.
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    June 2024
  10. HUANG KB, Wang FY, Lu Y, Yang LM, et al
    Cu(II) complex that synergistically potentiates cytotoxicity and an antitumor immune response by targeting cellular redox homeostasis.
    Proc Natl Acad Sci U S A. 2024;121:e2404668121.
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    May 2024
  11. YANG C, Dong X, Sun B, Cao T, et al
    Physical immune escape: Weakened mechanical communication leads to escape of metastatic colorectal carcinoma cells from macrophages.
    Proc Natl Acad Sci U S A. 2024;121:e2322479121.
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    March 2024
  12. MICHL J, White B, Monterisi S, Bodmer WF, et al
    Phenotypic screen of sixty-eight colorectal cancer cell lines identifies CEACAM6 and CEACAM5 as markers of acid resistance.
    Proc Natl Acad Sci U S A. 2024;121:e2319055121.
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  13. BONNET V, Maikranz E, Madec M, Vertti-Quintero N, et al
    Cancer-on-a-chip model shows that the adenomatous polyposis coli mutation impairs T cell engagement and killing of cancer spheroids.
    Proc Natl Acad Sci U S A. 2024;121:e2316500121.
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    February 2024
  14. JANSEN RA, Mainardi S, Dias MH, Bosma A, et al
    Small-molecule inhibition of MAP2K4 is synergistic with RAS inhibitors in KRAS-mutant cancers.
    Proc Natl Acad Sci U S A. 2024;121:e2319492121.
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  15. XIE B, Zhang M, Li J, Cui J, et al
    KAT8-catalyzed lactylation promotes eEF1A2-mediated protein synthesis and colorectal carcinogenesis.
    Proc Natl Acad Sci U S A. 2024;121:e2314128121.
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  16. YU Z, Deng P, Chen Y, Lin D, et al
    Pharmacological modulation of RB1 activity mitigates resistance to neoadjuvant chemotherapy in locally advanced rectal cancer.
    Proc Natl Acad Sci U S A. 2024;121:e2304619121.
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    December 2023
  17. SONG D, Hu F, Huang C, Lan J, et al
    Tiam1 methylation by NSD2 promotes Rac1 signaling activation and colon cancer metastasis.
    Proc Natl Acad Sci U S A. 2023;120:e2305684120.
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    November 2023
  18. DALEY BR, Vieira HM, Rao C, Hughes JM, et al
    SOS1 and KSR1 modulate MEK inhibitor responsiveness to target resistant cell populations based on PI3K and KRAS mutation status.
    Proc Natl Acad Sci U S A. 2023;120:e2313137120.
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    October 2023
  19. HUANG Y, Wang F, Lin X, Li Q, et al
    Nuclear VCP drives colorectal cancer progression by promoting fatty acid oxidation.
    Proc Natl Acad Sci U S A. 2023;120:e2221653120.
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    August 2023
  20. BHANDARI YR, Krishna V, Powers R, Parmar S, et al
    Transcription factor expression repertoire basis for epigenetic and transcriptional subtypes of colorectal cancers.
    Proc Natl Acad Sci U S A. 2023;120:e2301536120.
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    June 2023
  21. BEN-AKIVA E, Karlsson J, Hemmati S, Yu H, et al
    Biodegradable lipophilic polymeric mRNA nanoparticles for ligand-free targeting of splenic dendritic cells for cancer vaccination.
    Proc Natl Acad Sci U S A. 2023;120:e2301606120.
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    May 2023
  22. HSIEH FL, Chang TH, Gabelli SB, Nathans J, et al
    Structure of WNT inhibitor adenomatosis polyposis coli down-regulated 1 (APCDD1), a cell-surface lipid-binding protein.
    Proc Natl Acad Sci U S A. 2023;120:e2217096120.
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  23. AKIMOTO M, Susa T, Okudaira N, Koshikawa N, et al
    Hypoxia induces downregulation of the tumor-suppressive sST2 in colorectal cancer cells via the HIF-nuclear IL-33-GATA3 pathway.
    Proc Natl Acad Sci U S A. 2023;120:e2218033120.
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    March 2023
  24. CHEN S, Li K, Guo J, Chen HN, et al
    circNEIL3 inhibits tumor metastasis through recruiting the E3 ubiquitin ligase Nedd4L to degrade YBX1.
    Proc Natl Acad Sci U S A. 2023;120:e2215132120.
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    January 2023
  25. SOBOL RW
    WRN suppresses p53/PUMA-induced apoptosis in colorectal cancer with microsatellite instability/mismatch repair deficiency.
    Proc Natl Acad Sci U S A. 2023;120:e2219963120.
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    December 2022
  26. HAO S, Tong J, Jha A, Risnik D, et al
    Synthetical lethality of Werner helicase and mismatch repair deficiency is mediated by p53 and PUMA in colon cancer.
    Proc Natl Acad Sci U S A. 2022;119:e2211775119.
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  27. BAUMANN SJ, Grawenhoff J, Rodrigues EC, Speroni S, et al
    APC couples neuronal mRNAs to multiple kinesins, EB1, and shrinking microtubule ends for bidirectional mRNA motility.
    Proc Natl Acad Sci U S A. 2022;119:e2211536119.
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    May 2022
  28. YING Y, Wang M, Chen Y, Li M, et al
    Zinc finger protein 280C contributes to colorectal tumorigenesis by maintaining epigenetic repression at H3K27me3-marked loci.
    Proc Natl Acad Sci U S A. 2022;119:e2120633119.
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    November 2021
  29. SHIN JH, Jeong J, Maher SE, Lee HW, et al
    Colon cancer cells acquire immune regulatory molecules from tumor-infiltrating lymphocytes by trogocytosis.
    Proc Natl Acad Sci U S A. 2021;118.
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  30. NAERT T, Tulkens D, Van Nieuwenhuysen T, Przybyl J, et al
    CRISPR-SID: Identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping.
    Proc Natl Acad Sci U S A. 2021;118.
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  31. HO WW, Gomes-Santos IL, Aoki S, Datta M, et al
    Dendritic cell paucity in mismatch repair-proficient colorectal cancer liver metastases limits immune checkpoint blockade efficacy.
    Proc Natl Acad Sci U S A. 2021;118.
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    July 2021
  32. CHEN Y, Hao Q, Wang S, Cao M, et al
    Inactivation of the tumor suppressor p53 by long noncoding RNA RMRP.
    Proc Natl Acad Sci U S A. 2021;118.
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  33. ZHANG F, Qi L, Feng Q, Zhang B, et al
    HIPK2 phosphorylates HDAC3 for NF-kappaB acetylation to ameliorate colitis-associated colorectal carcinoma and sepsis.
    Proc Natl Acad Sci U S A. 2021;118.
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    June 2021
  34. HEUBERGER J, Grinat J, Kosel F, Liu L, et al
    High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53.
    Proc Natl Acad Sci U S A. 2021;118.
    >> Share


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