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Articles published in
Oncogene
    June 2026
  1. KONECNY T, Zadirako N, Grigoryan A, Tamazyan M, et al
    Transcriptomic profiling identifies immunotherapy-responsive phenotypes in microsatellite-stable metastatic colorectal cancer.
    Oncogene. 2026 Jun 16. doi: 10.1038/s41388-026-03861.
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  2. PARK SJ, Lee SW, Moon H, Jung SM, et al
    Amphiregulin drives EGFR-dependent genome stability in colorectal cancer and represents a targetable vulnerability.
    Oncogene. 2026 Jun 15. doi: 10.1038/s41388-026-03850.
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  3. DU J, Guo Z, Lu Q, Guo H, et al
    LncRNA 606938-TFAM axis drives oxidative stress and activates cGAS-STING pathway-mediated antitumor immunity to restrain colorectal cancer progression.
    Oncogene. 2026 Jun 6. doi: 10.1038/s41388-026-03839.
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  4. SU F, Zhou S, Gao Q, Lai M, et al
    High-fat diet promotes colorectal cancer via carnitine/acetylcarnitine-driven CPT1A metabolic reprogramming and the intervention of beta-hydroxybutyrate.
    Oncogene. 2026 Jun 4. doi: 10.1038/s41388-026-03835.
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  5. WANG Y, Wei Y, Bailey C, Peng G, et al
    HIF-1alpha integrates lipogenic FASN and glycolytic GLUT3 to overcome intratumor oxidative and hypoxic stress for colorectal cancer metastasis.
    Oncogene. 2026 Jun 3. doi: 10.1038/s41388-026-03738.
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  6. FENG M, He W, Ji G, Tong L, et al
    Carbohydrate responsive element binding protein promotes colorectal carcinogenesis via Wnt/beta-catenin pathway.
    Oncogene. 2026;45:1890-1900.
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    May 2026
  7. LI R, Ding R, Dan H, Du K, et al
    NDRG2 orchestrates circadian clock stability to suppress tumorigenesis and potentiate oxaliplatin response in colorectal cancer.
    Oncogene. 2026 May 19. doi: 10.1038/s41388-026-03823.
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  8. NIE H, Yu Y, Zhou J, Ning Y, et al
    GBP2 enhances anti-PD-L1 response in colorectal cancer via GSDMD-mediated YAP nuclear translocation by non-pyroptotic.
    Oncogene. 2026 May 11. doi: 10.1038/s41388-026-03816.
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  9. YANG MH, Sheth S, Shui B, Grabski IN, et al
    The impact of K-Ras Gly12 mutants on homeostasis and tumorigenesis in the colonic epithelium.
    Oncogene. 2026;45:1828-1839.
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    April 2026
  10. DEMMLER R, Anchang CG, Yong Y, Ramming A, et al
    Fibroblast dynamics in colorectal cancer: stability, plasticity, and novel markers.
    Oncogene. 2026 Apr 28. doi: 10.1038/s41388-026-03809.
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  11. LI C, Deng S, Zhuang M, Li T, et al
    MTPN drives noncanonical ERK hyperactivation in colorectal cancer and provides a promising therapeutic approach for precision medicine in CRC.
    Oncogene. 2026 Apr 20. doi: 10.1038/s41388-026-03795.
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  12. ZHENG Z, Ni Y, Wu M, Ding L, et al
    USP13 stabilizes SOCS1 to reverse alphaPD-1 resistance in MSI-H colorectal cancer.
    Oncogene. 2026 Apr 18. doi: 10.1038/s41388-026-03782.
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  13. ZHOU Z, La Ferlita A, Palavalli MH, Chen X, et al
    TWIST1 mediated transcriptional activation of SPON2 drives colorectal cancer peritoneal metastasis through stromal cell signaling network.
    Oncogene. 2026 Apr 3. doi: 10.1038/s41388-026-03743.
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  14. HE H, Yuan J, Wang H, Chen L, et al
    L1TD1 promotes colorectal mucinous adenocarcinoma progression by enhancing ABCC3 mRNA stability.
    Oncogene. 2026;45:1071-1086.
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  15. KUANG Z, Su Q, Liang W, Shen K, et al
    PRSS22 inhibits HMOX1-mediated ferroptosis and induces osteopontin cleavage to promote M2 macrophage polarization and colitis-associated carcinogenesis.
    Oncogene. 2026;45:1275-1286.
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    March 2026
  16. LI C, Liu Q, Shen H, Zou T, et al
    Fusobacterium nucleatum drives colorectal cancer progression through the circPTBP3/miR-760/PUM1 axis.
    Oncogene. 2026 Mar 31. doi: 10.1038/s41388-026-03746.
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  17. ZHANG H, Tian Y, Xiang Z, Han F, et al
    ZDHHC9-mediated KLF5 palmitoylation enhances the cAMP/PKA/CREB axis to promote colorectal cancer progression.
    Oncogene. 2026 Mar 25. doi: 10.1038/s41388-026-03724.
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  18. PENG Z, Ma B, Song Z, Zhao Y, et al
    PMM2 interacts with TRIM28 to recruit E2F4 and promote KIFC3-mediated tumor glycolysis and colorectal cancer progression.
    Oncogene. 2026 Mar 6. doi: 10.1038/s41388-026-03707.
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  19. CABALLERO-RUIZ B, Bordone R, Coni S, Gkotsi DS, et al
    Partial truncation of the C-terminal domain of PTCH1 in cancer promotes tumourigenesis by non-canonical activation of a GLI-PI3K loop.
    Oncogene. 2026;45:1013-1025.
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    February 2026
  20. ACEVEDO M, Do F, El-Mortada F, Tanguay PL, et al
    The deubiquitinase USP17 regulates the expression and activity of the oncogenic driver beta-catenin in colorectal cancer.
    Oncogene. 2026 Feb 19. doi: 10.1038/s41388-026-03695.
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    January 2026
  21. WANG B, Zhang S, Guo Y, Gao W, et al
    Correction: CBX2 as a therapeutic target in colorectal cancer: insights into the altered chromatin accessibility via RUNX1-CBX2-MAP4K1 axis.
    Oncogene. 2026 Jan 21. doi: 10.1038/s41388-026-03677.
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  22. SU J, Zhao M, Feng W, Lin Y, et al
    TAF1 acetyltransferase promotes colorectal carcinoma metastasis by catalyzing beta-hydroxybutyrylation of KCTD9.
    Oncogene. 2026;45:87-103.
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    December 2025
  23. WANG H, Ge L, Li J, Zhong K, et al
    NAT10 triggers colorectal cancer progression via promoting PPAN-regulated DNA damage repair.
    Oncogene. 2025 Dec 27. doi: 10.1038/s41388-025-03661.
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  24. HUANG M, Xie W, Wu M, Ou Z, et al
    KRT81 promotes metastasis of colorectal cancer by acting as a protein scaffold for ezrin.
    Oncogene. 2025 Dec 17. doi: 10.1038/s41388-025-03665.
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  25. YANG LP, Huang JQ, Yeung CW, Zhang QH, et al
    Targeted methylation of cg24067911 suppresses colorectal cancer metastasis through BCL6-ATXN1-CDH1 axis.
    Oncogene. 2025 Dec 2. doi: 10.1038/s41388-025-03638.
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    November 2025
  26. LV M, Hu C, Li J, Zhang Y, et al
    Serotonin receptor type 7 (5-HT7) promotes colorectal cancer progression by activating Wnt/beta-catenin signaling via interacting with CK1epsilon.
    Oncogene. 2025 Nov 26. doi: 10.1038/s41388-025-03645.
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  27. SMABERS LP, Nienhuis HH, de Leng WWJ, Roepman P, et al
    Clinical implications of whole genome sequencing in metastatic colorectal cancer.
    Oncogene. 2025 Nov 7. doi: 10.1038/s41388-025-03618.
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    October 2025
  28. HU Y, Liu W, Qiang D, Huang K, et al
    Emerging roles of RNA-binding protein hnRNPM in alternative splicing regulation and UTMD mediated sh-hnRNPM/CMBs suppress the proliferation of colorectal cancer.
    Oncogene. 2025 Oct 19. doi: 10.1038/s41388-025-03599.
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  29. HUANG M, Qin B, Xie Z, Zhou R, et al
    Publisher Correction: RCN3 functions as a tumor promoter in colorectal cancer by modulating the GRP78-PI3K-AKT signaling pathway.
    Oncogene. 2025 Oct 8. doi: 10.1038/s41388-025-03592.
    >> Share

  30. LANZLOTH R, Harris NL, Cannon AM, Kaplan MH, et al
    Mast cells interact directly with colorectal cancer cells to promote epithelial-to-mesenchymal transition.
    Oncogene. 2025 Oct 2. doi: 10.1038/s41388-025-03589.
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    September 2025
  31. LIN P, Lin C, Teng Z, Liu S, et al
    USP10-mediated Ku70/80 stabilization inhibits PANoptosis and promotes chemoresistance in colorectal cancer.
    Oncogene. 2025 Sep 18. doi: 10.1038/s41388-025-03570.
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  32. YIN Y, Ming L, Qin Y, Tang J, et al
    RAB22A triggers intercellular chemoresistance transmission in colorectal cancer by promoting exosome release via the PKM2-pSNAP23 axis.
    Oncogene. 2025 Sep 16. doi: 10.1038/s41388-025-03566.
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  33. REN Y, Chen J, Zhan X, Sheng S, et al
    Correction: Liquid-liquid phase separation of GPS2-LATS1 promotes colorectal cancer progression by reprogramming lipid metabolism.
    Oncogene. 2025 Sep 10. doi: 10.1038/s41388-025-03540.
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  34. TRAN TQ, Duysak T, Kim K, Dang GC, et al
    Anti-cancer effect of interleukin-2 fused to flagellin expressed by tumor-targeting Salmonella.
    Oncogene. 2025;44:3449-3460.
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    August 2025
  35. STRELEZ C, Battaglin F, Perez R, Yang Y, et al
    GABAergic signaling contributes to tumor cell invasion and poor overall survival in colorectal cancer.
    Oncogene. 2025 Aug 24. doi: 10.1038/s41388-025-03546.
    >> Share

  36. HUANG M, Qin B, Xie Z, Zhou R, et al
    RCN3 functions as a tumor promoter in colorectal cancer by modulating the GRP78-PI3K-AKT signaling pathway.
    Oncogene. 2025 Aug 23. doi: 10.1038/s41388-025-03535.
    >> Share

  37. WANG YN, Zeng ZL, Lu J, Wang Y, et al
    Correction: CPT1A-mediated fatty acid oxidation promotes colorectal cancer cell metastasis by inhibiting anoikis.
    Oncogene. 2025 Aug 7. doi: 10.1038/s41388-025-03508.
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  38. IDEN JA, Ben-Califa N, Naim A, Liron T, et al
    Immunomodulatory function of cannabinoid receptor 2 and its agonist osteogenic growth peptide in health and cancer: a study in mice and humans.
    Oncogene. 2025;44:2504-2514.
    >> Share

    July 2025
  39. REN Y, Chen J, Zhan X, Sheng S, et al
    Liquid-liquid phase separation of GPS2-LATS1 promotes colorectal cancer progression by reprogramming lipid metabolism.
    Oncogene. 2025 Jul 25. doi: 10.1038/s41388-025-03498.
    >> Share

  40. TARRADO-CASTELLARNAU M, Foguet C, Tarrago-Celada J, Palobart M, et al
    Glutaminase as a metabolic target of choice to counter acquired resistance to Palbociclib by colorectal cancer cells.
    Oncogene. 2025 Jul 22. doi: 10.1038/s41388-025-03495.
    >> Share

  41. CONG B, Thakur T, Uribe AH, Stamou E, et al
    Colon cancer cells evade drug action by enhancing drug metabolism.
    Oncogene. 2025 Jul 10. doi: 10.1038/s41388-025-03472.
    >> Share

  42. HAN H, Li Y, Lin Z, Ma X, et al
    ALKBH5 suppresses m(6)A mRNA modification of FOXM1 to drive Cetuximab resistance in KRAS-mutant colorectal cancer.
    Oncogene. 2025 Jul 7. doi: 10.1038/s41388-025-03490.
    >> Share

  43. JAYACHANDRAN P, Elliott A, Soni S, Battaglin F, et al
    Pan-RAS inhibitors and polo-like kinase 1: promising targets in colorectal cancer.
    Oncogene. 2025 Jul 4. doi: 10.1038/s41388-025-03484.
    >> Share

  44. ZHAO M, Nie J, Ye A, Liu C, et al
    Impaired autophagy by cepharanthine induces immunogenic cell death and enhances anti-PD-1 response in MSS-type colorectal cancer.
    Oncogene. 2025 Jul 3. doi: 10.1038/s41388-025-03488.
    >> Share

    June 2025
  45. WU H, Hu X, Wang Y, Zhu X, et al
    RBM5 recruiting MGC32805 in a sandwich mode and inducing DeltaFAS neoantigen and triggering FAS properties switch: implication in colorectal cancer.
    Oncogene. 2025 Jun 26. doi: 10.1038/s41388-025-03390.
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  46. GUO ST, Jiang CC, Wang GP, Li YP, et al
    Correction: MicroRNA-497 targets insulin-like growth factor 1 receptor and has a tumour suppressive role in human colorectal cancer.
    Oncogene. 2025 Jun 3. doi: 10.1038/s41388-025-03446.
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  47. GU J, Xu X, Li X, Yue L, et al
    Correction: Tumor-resident microbiota contributes to colorectal cancer liver metastasis by lactylation and immune modulation.
    Oncogene. 2025 Jun 2. doi: 10.1038/s41388-025-03439.
    >> Share

  48. BAI X, Duan T, Shao J, Zhang Y, et al
    CBX3 promotes multidrug resistance by suppressing ferroptosis in colorectal carcinoma via the CUL3/NRF2/GPX2 axis.
    Oncogene. 2025;44:1678-1693.
    >> Share

    May 2025
  49. QU S, Feng B, Xing M, Qiu Y, et al
    PRMT5 K240lac confers ferroptosis resistance via ALKBH5/SLC7A11 axis in colorectal cancer.
    Oncogene. 2025 May 30. doi: 10.1038/s41388-025-03457.
    >> Share

  50. PAN D, Hu J, Li G, Gao X, et al
    BRD4 regulates PAI-1 expression in tumor-associated macrophages to drive chemoresistance in colorectal cancer.
    Oncogene. 2025 May 28. doi: 10.1038/s41388-025-03453.
    >> Share

    April 2025
  51. WOUTERS VM, Helderman RFCPA, Cameron K, van der Hooff SR, et al
    CDX2 downregulation regulates intrinsic WNT pathway activation, dictating metastasis in APC and CTNNB1 wildtype colorectal cancer.
    Oncogene. 2025 Apr 6. doi: 10.1038/s41388-025-03365.
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    March 2025
  52. TAIRA A, Aavikko M, Katainen R, Kaasinen E, et al
    Comprehensive metabolomic and epigenomic characterization of microsatellite stable BRAF-mutated colorectal cancer.
    Oncogene. 2025 Mar 18. doi: 10.1038/s41388-025-03326.
    >> Share

  53. WANG B, Zhang S, Guo Y, Gao W, et al
    CBX2 as a therapeutic target in colorectal cancer: insights into the altered chromatin accessibility via RUNX1-CBX2-MAP4K1 axis.
    Oncogene. 2025 Mar 13. doi: 10.1038/s41388-025-03331.
    >> Share

    February 2025
  54. SHENG Z, Luo S, Huang L, Deng YN, et al
    SENP1-mediated deSUMOylation of YBX1 promotes colorectal cancer development through the SENP1-YBX1-AKT signaling axis.
    Oncogene. 2025 Feb 23. doi: 10.1038/s41388-025-03302.
    >> Share

  55. YAN Z, He L, Yuan J, Niu Y, et al
    The splicing factor SRRM2 modulates two S6K kinases to promote colorectal cancer growth.
    Oncogene. 2025 Feb 16. doi: 10.1038/s41388-025-03307.
    >> Share

  56. ZHANG J, Zhai J, Wong CC, Chen H, et al
    Correction: A novel amplification gene PCI domain containing 2 (PCID2) promotes colorectal cancer through directly degrading a tumor suppressor promyelocytic leukemia (PML).
    Oncogene. 2025 Feb 12. doi: 10.1038/s41388-025-03304.
    >> Share

  57. RUAN DY, Li T, Wang YN, Meng Q, et al
    Correction: FTO downregulation mediated by hypoxia facilitates colorectal cancer metastasis.
    Oncogene. 2025 Feb 4. doi: 10.1038/s41388-025-03287.
    >> Share

    January 2025
  58. REISSLAND M, Hartmann O, Tauch S, Bugter JM, et al
    Correction: USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer.
    Oncogene. 2025 Jan 22. doi: 10.1038/s41388-024-03262.
    >> Share

    December 2024
  59. LIAO Y, Yang R, Wang B, Ruan Y, et al
    Mevalonate kinase inhibits anti-tumor immunity by impairing the tumor cell-intrinsic interferon response in microsatellite instability colorectal cancer.
    Oncogene. 2024 Dec 26. doi: 10.1038/s41388-024-03255.
    >> Share

    November 2024
  60. ZHUANG M, Liu J, Li Y, Zhang J, et al
    PD-L1 promotes tumor metastasis by regulating the infiltration of FGFBP2(+)Tm cells in colorectal cancer.
    Oncogene. 2024 Nov 18. doi: 10.1038/s41388-024-03223.
    >> Share

  61. WEN M, Qiu Y, Wang M, Tang F, et al
    Enhancing low-dose radiotherapy efficacy with PARP inhibitors via FBL-mediated oxidative stress response in colorectal cancer.
    Oncogene. 2024 Nov 8. doi: 10.1038/s41388-024-03207.
    >> Share

  62. DUYSAK T, Kim K, Yun M, Jeong JH, et al
    Enhanced anti-cancer efficacy of arginine deaminase expressed by tumor-seeking Salmonella Gallinarum.
    Oncogene. 2024;43:3378-3387.
    >> Share

  63. BORDONE R, Ivy DM, D'Amico R, Barba M, et al
    MYC upstream region orchestrates resistance to PI3K inhibitors in cancer cells through FOXO3a-mediated autophagic adaptation.
    Oncogene. 2024;43:3349-3365.
    >> Share

    October 2024
  64. BORDING T, Janik T, Bischoff P, Morkel M, et al
    GPA33 expression in colorectal cancer can be induced by WNT inhibition and targeted by cellular therapy.
    Oncogene. 2024 Oct 29. doi: 10.1038/s41388-024-03200.
    >> Share

  65. REISSLAND M, Hartmann O, Tauch S, Bugter JM, et al
    USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer.
    Oncogene. 2024 Oct 23. doi: 10.1038/s41388-024-03141.
    >> Share

  66. LIN W, Xu L, Li Y, Li J, et al
    Aberrant FAM135B attenuates the efficacy of chemotherapy in colorectal cancer by modulating SRSF1-mediated alternative splicing.
    Oncogene. 2024 Oct 13. doi: 10.1038/s41388-024-03189.
    >> Share

  67. HAN F, Zhou X, Liu L, Yang B, et al
    GLTSCR1 deficiency promotes colorectal cancer development through regulating non-homologous end joining.
    Oncogene. 2024 Oct 11. doi: 10.1038/s41388-024-03179.
    >> Share

    September 2024
  68. XU H, Wang T, Nie H, Sun Q, et al
    USP36 promotes colorectal cancer progression through inhibition of p53 signaling pathway via stabilizing RBM28.
    Oncogene. 2024 Sep 29. doi: 10.1038/s41388-024-03178.
    >> Share

  69. SUN Z, Dang P, Guo Y, Liu S, et al
    Targeting CircAURKA prevents colorectal cancer progression via enhancing CTNNB1 protein degradation.
    Oncogene. 2024 Sep 28. doi: 10.1038/s41388-024-03155.
    >> Share

  70. TANG W, Yang Y, Fu Z, Xu W, et al
    The RNA helicase DDX21 activates YAP to promote tumorigenesis and is transcriptionally upregulated by beta-catenin in colorectal cancer.
    Oncogene. 2024 Sep 17. doi: 10.1038/s41388-024-03160.
    >> Share

  71. CHURCHHOUSE AMD, Billard CV, Suzuki T, Pohl SOG, et al
    Loss of DOCK2 potentiates Inflammatory Bowel Disease-associated colorectal cancer via immune dysfunction and IFNgamma induction of IDO1 expression.
    Oncogene. 2024 Sep 7. doi: 10.1038/s41388-024-03135.
    >> Share

    August 2024
  72. GUPTA A, Avadhanula S, Bashyam MD
    Evaluation of the gene fusion landscape in early onset sporadic rectal cancer reveals association with chromatin architecture and genome stability.
    Oncogene. 2024;43:2449-2462.
    >> Share

    July 2024
  73. LI X, Chen Y, Lu R, Hu M, et al
    Correction: Colorectal cancer cells secreting DKK4 transform fibroblasts to promote tumour metastasis.
    Oncogene. 2024 Jul 15. doi: 10.1038/s41388-024-03101.
    >> Share

    June 2024
  74. GU J, Xu X, Li X, Yue L, et al
    Tumor-resident microbiota contributes to colorectal cancer liver metastasis by lactylation and immune modulation.
    Oncogene. 2024 Jun 18. doi: 10.1038/s41388-024-03080.
    >> Share

  75. FENG M, Chai C, Hao X, Lai X, et al
    Inherited KDM6A(A649T) facilitates tumor-immune escape and exacerbates colorectal signet-ring cell carcinoma outcomes.
    Oncogene. 2024;43:1757-1768.
    >> Share

    April 2024
  76. CAO N, Zhang F, Yin J, Zhang J, et al
    LPCAT2 inhibits colorectal cancer progression via the PRMT1/SLC7A11 axis.
    Oncogene. 2024 Apr 11. doi: 10.1038/s41388-024-02996.
    >> Share

  77. WU Q, Wang Z, Chen S, She X, et al
    USP26 promotes colorectal cancer tumorigenesis by restraining PRKN-mediated mitophagy.
    Oncogene. 2024 Apr 2. doi: 10.1038/s41388-024-03009.
    >> Share

    March 2024
  78. LI X, Chen Y, Lu R, Hu M, et al
    Colorectal cancer cells secreting DKK4 transform fibroblasts to promote tumour metastasis.
    Oncogene. 2024 Mar 22. doi: 10.1038/s41388-024-03008.
    >> Share


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