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Articles published in
Cancer Res
    June 2024
  1. LI L, Jiang D, Liu H, Guo C, et al
    Comprehensive Proteogenomic Profiling Reveals the Molecular Characteristics of Colorectal Cancer at Distinct Stages of Progression.
    Cancer Res. 2024 Jun 11. doi: 10.1158/0008-5472.CAN-23-1878.
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    May 2024
  2. BAKER AM, Nageswaran G, Nenclares P, Ronel T, et al
    FUME-TCRseq Enables Sensitive and Accurate Sequencing of the T-cell Receptor from Limited Input of Degraded RNA.
    Cancer Res. 2024;84:1560-1569.
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  3. BAHRAMBEIGI V, Lee JJ, Branchi V, Rajapakshe KI, et al
    Transcriptomic Profiling of Plasma Extracellular Vesicles Enables Reliable Annotation of the Cancer-Specific Transcriptome and Molecular Subtype.
    Cancer Res. 2024;84:1719-1732.
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    April 2024
  4. YANG S, Zhang D, Sun Q, Nie H, et al
    Single-Cell and Spatial Transcriptome Profiling Identifies the Transcription Factor BHLHE40 as a Driver of EMT in Metastatic Colorectal Cancer.
    Cancer Res. 2024 Apr 24. doi: 10.1158/0008-5472.CAN-23-3264.
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  5. ZHAO N, Cao Y, Tao R, Zhu X, et al
    The circMYBL2-encoded p185 protein suppresses colorectal cancer progression by inhibiting serine biosynthesis.
    Cancer Res. 2024 Apr 18. doi: 10.1158/0008-5472.CAN-23-2940.
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  6. CHEN Y, Ying Y, Ma W, Ma H, et al
    Targeting the Epigenetic Reader ENL Inhibits Super-Enhancer-Driven Oncogenic Transcription and Synergizes with BET Inhibition to Suppress Tumor Progression.
    Cancer Res. 2024;84:1237-1251.
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    March 2024
  7. MCCOLLUM SE, Shah YM
    Stressing Out Cancer: Chronic Stress Induces Dysbiosis and Enhances Colon Cancer Growth.
    Cancer Res. 2024;84:645-647.
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  8. FANG L, Zhang L, Wang M, He Y, et al
    Pooled CRISPR Screening Identifies P-Bodies as Repressors of Cancer Epithelial-Mesenchymal Transition.
    Cancer Res. 2024;84:659-674.
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    February 2024
  9. LIU X, Wang X, Yang Q, Luo L, et al
    Th17 cells secrete TWEAK to trigger epithelial-mesenchymal transition and promote colorectal cancer liver metastasis.
    Cancer Res. 2024 Feb 9. doi: 10.1158/0008-5472.CAN-23-2123.
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    January 2024
  10. ZHANG R, Kang R, Tang D
    Gut microbiome mediates ferroptosis resistance for colorectal cancer development.
    Cancer Res. 2024 Jan 26. doi: 10.1158/0008-5472.CAN-24-0275.
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  11. CAO Q, Zhao M, Su Y, Liu S, et al
    Chronic stress dampens Lactobacillus johnsonii-mediated tumor suppression to enhance colorectal cancer progression.
    Cancer Res. 2024 Jan 8. doi: 10.1158/0008-5472.CAN-22-3705.
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  12. MULLER S, Krishnamurty AT
    One Mutation to Rule Them All: Mutant KRAS Controls Tumor Intrinsic and Microenvironment Signaling.
    Cancer Res. 2024;84:6-8.
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  13. WANG D, Nakayama M, Hong CP, Oshima H, et al
    Gain-of-Function p53 Mutation Acts as a Genetic Switch for TGFbeta Signaling-Induced Epithelial-to-Mesenchymal Transition in Intestinal Tumors.
    Cancer Res. 2024;84:56-68.
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    November 2023
  14. RIQUELME E, Howell RM, McAllister F
    Microbial Regulation of Vitamin D Linked to Colorectal Cancer: A Sex Bias.
    Cancer Res. 2023;83:3670-3672.
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  15. BUSH CO, Perry RJ
    Molecular Mechanism of Fasting-Mimicking Diet in Inhibiting Colorectal Cancer Progression: Implications for Immune Therapy and Metabolic Regulation.
    Cancer Res. 2023;83:3493-3494.
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  16. LI B, Cai Y, Chen C, Li G, et al
    Genetic Variants That Impact Alternative Polyadenylation in Cancer Represent Candidate Causal Risk Loci.
    Cancer Res. 2023;83:3650-3666.
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  17. CHEN Z, Zhang G, Ren X, Yao Z, et al
    Cross-talk between Myeloid and B Cells Shapes the Distinct Microenvironments of Primary and Secondary Liver Cancer.
    Cancer Res. 2023;83:3544-3561.
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    October 2023
  18. LIU S, Locasale JW
    Delineating a role for methionine metabolism in colorectal cancer.
    Cancer Res. 2023 Oct 17. doi: 10.1158/0008-5472.CAN-23-3169.
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    August 2023
  19. ZHENG Y, Zhou R, Cai J, Yang N, et al
    Matrix stiffness triggers lipid metabolic crosstalk between tumor and stromal cells to mediate bevacizumab resistance in colorectal cancer liver metastases.
    Cancer Res. 2023 Aug 23:CAN-23-0025. doi: 10.1158/0008-5472.CAN-23-0025.
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  20. ZHONG Z, Zhang H, Nan K, Zhong J, et al
    Fasting-mimicking diet drives antitumor immunity against colorectal cancer by reducing IgA-producing cells.
    Cancer Res. 2023 Aug 21:CAN-23-0323. doi: 10.1158/0008-5472.CAN-23-0323.
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  21. XIE Y, Li P, Sun D, Qi Q, et al
    DNA methylation-based testing in peripheral blood mononuclear cells enables accurate and early detection of colorectal cancer.
    Cancer Res. 2023 Aug 21:CAN-22-3402. doi: 10.1158/0008-5472.CAN-22-3402.
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  22. TANG J, Wang S, Weng M, Guo Q, et al
    The IGF2BP3-COPS7B axis facilitates mRNA translation to drive colorectal cancer progression.
    Cancer Res. 2023 Aug 10:CAN-23-0557. doi: 10.1158/0008-5472.CAN-23-0557.
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    June 2023
  23. WEI M, Huang X, Liao L, Tian Y, et al
    SENP1 decreases RNF168 phase separation to promote DNA damage repair and drug resistance in colon cancer.
    Cancer Res. 2023 Jun 23:CAN-22-4017. doi: 10.1158/0008-5472.CAN-22-4017.
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  24. JAILKHANI N, Clauser KR, Mak HH, Rickelt S, et al
    Proteomic Profiling of Extracellular Matrix Components from Patient Metastases Identifies Consistently Elevated Proteins for Developing Nanobodies That Target Primary Tumors and Metastases.
    Cancer Res. 2023;83:2052-2065.
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    May 2023
  25. AGLAGO EK, Kim AE, Lin Y, Qu C, et al
    A genetic locus within the FMN1/GREM1 gene region interacts with body mass index in colorectal cancer risk.
    Cancer Res. 2023 May 30:CAN-22-3713. doi: 10.1158/0008-5472.CAN-22-3713.
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  26. HUANG X, Sun T, Wang J, Hong X, et al
    Metformin reprograms tryptophan metabolism to stimulate CD8+ T cell function in colorectal cancer.
    Cancer Res. 2023 May 17:CAN-22-3042. doi: 10.1158/0008-5472.CAN-22-3042.
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    April 2023
  27. LI S, Du M, Xu K, Ben S, et al
    A germline variant in the BET1L 3'-UTR confers colorectal cancer susceptibility by reducing miRNA binding and m6A modification.
    Cancer Res. 2023 Apr 28:CAN-22-0065. doi: 10.1158/0008-5472.CAN-22-0065.
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  28. WATLING CZ, Kelly RK, Murphy N, Gunter M, et al
    Prospective analysis reveals associations between carbohydrate intakes, genetic predictors of short-chain fatty acid synthesis, and colorectal cancer risk.
    Cancer Res. 2023 Apr 25:CAN-22-3755. doi: 10.1158/0008-5472.CAN-22-3755.
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  29. WOOD CS, Pennel KAF, Leslie H, Legrini A, et al
    Spatially Resolved Transcriptomics Deconvolutes Prognostic Histological Subgroups in Patients with Colorectal Cancer and Synchronous Liver Metastases.
    Cancer Res. 2023;83:1329-1344.
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    March 2023
  30. MILLER AL, Perurena N, Gardner A, Hinoue T, et al
    DAB2IP is a bifunctional tumor suppressor that regulates wildtype RAS and inflammatory cascades in KRAS mutant colon cancer.
    Cancer Res. 2023 Mar 20:CAN-22-0370. doi: 10.1158/0008-5472.CAN-22-0370.
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    December 2022
  31. YUE T, Li J, Zhu J, Zuo S, et al
    Hydrogen sulfide creates a favorable immune microenvironment for colon cancer.
    Cancer Res. 2022 Dec 16:CAN-22-1837. doi: 10.1158/0008-5472.CAN-22-1837.
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  32. ZOU S, Qin B, Yang Z, Wang W, et al
    CSN6 mediates nucleotide metabolism to promote tumor development and chemoresistance in colorectal cancer.
    Cancer Res. 2022 Dec 13:CAN-22-2145. doi: 10.1158/0008-5472.CAN-22-2145.
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    October 2022
  33. SANDERS BE, Qiao G, Hirschman J, Meyerson M, et al
    Fusobacterium and Colorectal Cancer: Important Association or Random Coincidence?
    Cancer Res. 2022;82:3671-3672.
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  34. LOEVENICH LP, Tschurtschenthaler M, Rokavec M, Silva MG, et al
    SMAD4 loss induces c-MYC-mediated NLE1 upregulation to support protein biosynthesis, colorectal cancer growth and metastasis.
    Cancer Res. 2022 Oct 11. pii: 709708. doi: 10.1158/0008-5472.CAN-22-1247.
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    September 2022
  35. BOUSTANY LM, LaPorte SL, Wong L, White C, et al
    A Probody(R) T-cell-engaging bispecific antibody targeting EGFR and CD3 inhibits colon cancer growth with limited toxicity.
    Cancer Res. 2022 Sep 16. pii: 709245. doi: 10.1158/0008-5472.CAN-21-2483.
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  36. FUJISHITA T, Kojima Y, Kajino-Sakamoto R, Mishiro-Sato E, et al
    The cAMP/PKA/CREB and TGF-beta/SMAD4 pathways regulate stemness and metastatic potential in colorectal cancer cells.
    Cancer Res. 2022 Sep 6. pii: 708953. doi: 10.1158/0008-5472.CAN-22-1369.
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  37. CHEN Y, Yan SM, Pu Z, Feng J, et al
    Dopamine Signaling Promotes Tissue-Resident Memory Differentiation of CD8+ T Cells and Antitumor Immunity.
    Cancer Res. 2022;82:3130-3142.
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    August 2022
  38. SOROKIN AV, Kanikarla Marie P, Bitner L, Syed M, et al
    Targeting RAS mutant colorectal cancer with dual inhibition of MEK and CDK4/6.
    Cancer Res. 2022 Aug 1. pii: 707348. doi: 10.1158/0008-5472.CAN-22-0198.
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    May 2022
  39. HEINZ MC, Peters NA, Oost KC, Lindeboom RGH, et al
    Liver Colonization by Colorectal Cancer Metastases Requires YAP-Controlled Plasticity at the Micrometastatic Stage.
    Cancer Res. 2022;82:1953-1968.
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  40. LEBLEU VS
    Plasticity Enables Cooperation among Heterogeneous Cancer Cell Populations to Support Metastatic Fitness.
    Cancer Res. 2022;82:1870-1871.
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    April 2022
  41. HSU KS, Adileh M, Martin ML, Makarov V, et al
    Colorectal cancer develops inherent radiosensitivity that can be predicted using patient-derived organoids.
    Cancer Res. 2022 Apr 26. pii: 694761. doi: 10.1158/0008-5472.CAN-21-4128.
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  42. MONTROSE DC, Galluzzi L
    Restored Ketosis Drives Anticancer Immunity in Colorectal Cancer.
    Cancer Res. 2022;82:1464-1466.
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  43. ZHANG L, Pickard K, Jenei V, Bullock MD, et al
    Editor's Note: miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance.
    Cancer Res. 2022;82:1669.
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  44. MATAS J, Kohrn B, Fredrickson J, Carter K, et al
    Colorectal Cancer Is Associated with the Presence of Cancer Driver Mutations in Normal Colon.
    Cancer Res. 2022;82:1492-1502.
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  45. MALIER M, Gharzeddine K, Laverriere MH, Marsili S, et al
    Correction: Hypoxia Drives Dihydropyrimidine Dehydrogenase Expression in Macrophages and Confers Chemoresistance in Colorectal Cancer.
    Cancer Res. 2022;82:1436.
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  46. ISSA JP
    The Two-Hit Hypothesis Meets Epigenetics.
    Cancer Res. 2022;82:1167-1169.
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    March 2022
  47. WEI R, Zhou Y, Li C, Rychahou P, et al
    Ketogenesis attenuates KLF5-dependent production of CXCL12 to overcome the immunosuppressive tumor microenvironment in colorectal cancer.
    Cancer Res. 2022 Mar 3. pii: 681994. doi: 10.1158/0008-5472.CAN-21-2778.
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    January 2022
  48. MENG Y, Du M, Gu D, Li C, et al
    Genome-wide association analyses identify CATSPERE as a mediator of colorectal cancer susceptibility and progression.
    Cancer Res. 2022 Jan 24. pii: 0008-5472.CAN-21-2948.
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    December 2021
  49. FAN F, Liu P, Bao R, Chen J, et al
    A Dual PI3K/HDAC Inhibitor Induces Immunogenic Ferroptosis to Potentiate Cancer Immune Checkpoint Therapy.
    Cancer Res. 2021;81:6233-6245.
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    November 2021
  50. PAIDI SK, Rodriguez Troncoso J, Raj P, Monterroso Diaz P, et al
    Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy.
    Cancer Res. 2021;81:5745-5755.
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  51. SENDI H, Yazdimamaghani M, Hu M, Sultanpuram N, et al
    Nanoparticle delivery of miR-122 inhibits colorectal cancer liver metastasis.
    Cancer Res. 2021 Nov 9. pii: 0008-5472.CAN-21-2269.
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  52. COOK DR, Kang M, Martin TD, Galanko JA, et al
    Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth.
    Cancer Res. 2021 Nov 4. pii: 0008-5472.CAN-20-4218.
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  53. BERLIN C, Cottard F, Willmann D, Urban S, et al
    KMT9 controls stemness and growth of colorectal cancer.
    Cancer Res. 2021 Nov 4. pii: 0008-5472.CAN-21-1261.
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  54. KWON M, Rubio G, Nolan N, Auteri P, et al
    FILIP1L Loss Is a Driver of Aggressive Mucinous Colorectal Adenocarcinoma and Mediates Cytokinesis Defects through PFDN1.
    Cancer Res. 2021;81:5523-5539.
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    October 2021
  55. GEN Y, Muramatsu T, Inoue J, Inazawa J, et al
    miR-766-5p Targets Super-Enhancers by Downregulating CBP and BRD4.
    Cancer Res. 2021;81:5190-5201.
    >> Share

  56. MALIER M, Gharzeddine K, Laverriere MH, Marsili S, et al
    Hypoxia drives dihydropyrimidine dehydrogenase expression in macrophages and confers chemoresistance in colorectal cancer.
    Cancer Res. 2021 Oct 13. pii: 0008-5472.CAN-21-1572.
    >> Share

  57. ZHENG X, Liu R, Zhou C, Yu H, et al
    ANGPTL4-mediated promotion of glycolysis facilitates the colonization of Fusobacterium nucleatum in colorectal cancer.
    Cancer Res. 2021 Oct 13. pii: 0008-5472.CAN-21-2273.
    >> Share

    September 2021
  58. NAPOLI M, Deshpande AA, Flores ER
    The Landmark Discovery That Paved the Way to a Mechanistic Understanding of P53 Gain of Function and Personalized Medicine.
    Cancer Res. 2021;81:4394-4396.
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    July 2021
  59. WINTER M, Rokavec M, Hermeking H
    14-3-3sigma Functions as an Intestinal Tumor Suppressor.
    Cancer Res. 2021;81:3621-3634.
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  60. STEINER MC, Marston JL, Iniguez LP, Bendall ML, et al
    Locus-Specific Characterization of Human Endogenous Retrovirus Expression in Prostate, Breast, and Colon Cancers.
    Cancer Res. 2021;81:3449-3460.
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  61. SAIDA Y, Brender JR, Yamamoto K, Mitchell JB, et al
    Multimodal Molecular Imaging Detects Early Responses to Immune Checkpoint Blockade.
    Cancer Res. 2021;81:3693-3705.
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    June 2021
  62. PHILLIPS DC, Buchanan FG, Cheng D, Solomon LR, et al
    Hexavalent TRAIL Fusion Protein Eftozanermin Alfa Optimally Clusters Apoptosis-Inducing TRAIL Receptors to Induce On-Target Antitumor Activity in Solid Tumors.
    Cancer Res. 2021;81:3402-3414.
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  63. O'CONNELL CE, Vassilev A
    Combined Inhibition of p38MAPK and PIKfyve Synergistically Disrupts Autophagy to Selectively Target Cancer Cells.
    Cancer Res. 2021;81:2903-2917.
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  64. WANG HQ, Mulford IJ, Sharp F, Liang J, et al
    Inhibition of MDM2 Promotes Antitumor Responses in p53 Wild-Type Cancer Cells through Their Interaction with the Immune and Stromal Microenvironment.
    Cancer Res. 2021;81:3079-3091.
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    May 2021
  65. BOMMI PV, Bowen CM, Reyes-Uribe L, Wu W, et al
    The Transcriptomic Landscape of Mismatch Repair-Deficient Intestinal Stem Cells.
    Cancer Res. 2021;81:2760-2773.
    >> Share

  66. WANG X, Jia Y, Wen L, Mu W, et al
    Porphyromonas gingivalis Promotes Colorectal Carcinoma by Activating the Hematopoietic NLRP3 Inflammasome.
    Cancer Res. 2021;81:2745-2759.
    >> Share

  67. FRAU C, Jamard C, Delpouve G, Guardia GDA, et al
    Deciphering the Role of Intestinal Crypt Cell Populations in Resistance to Chemotherapy.
    Cancer Res. 2021;81:2730-2744.
    >> Share

  68. YANG B, Li X, Fu Y, Guo E, et al
    MEK Inhibition Remodels the Immune Landscape of Mutant KRAS Tumors to Overcome Resistance to PARP and Immune Checkpoint Inhibitors.
    Cancer Res. 2021;81:2714-2729.
    >> Share


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