March 2026
1. ZHANG S, Zhou L, Hong B, van den Heuvel APJ, et al
   Editor's Note: Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53.
   Cancer Res. 2026;86:1526.
   

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2. XIA Z, De Vuyst F, Ernst S, Suwal U, et al
   PI3K and MAPK Signaling Nodes Serve as Divergent Drivers of Phenotypic Plasticity in Cancer-Associated Fibroblasts in Colorectal Cancer.
   Cancer Res. 2026 Mar 12. doi: 10.1158/0008-5472.CAN-25-0766.
   

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3. LI W, Peng J, He J, Liao L, et al
   PKM2 Lactylation Promotes Colorectal Cancer Vasculogenic Mimicry and Bevacizumab Resistance by Facilitating FOSL1 Super-Enhancer Formation.
   Cancer Res. 2026 Mar 5. doi: 10.1158/0008-5472.CAN-25-3520.
   

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4. SWIFT SZ, Webster J, Mai H, Othoum G, et al
   Integration of Short- and Long-Read RNA Sequencing Enables the Discovery of Circular RNAs.
   Cancer Res. 2026;86:1300-1318.
   

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   February 2026
5. RONDEAU V, Bansal S, Buttigieg MM, Zeng AGX, et al
   Response to Immune Checkpoint Blockade Is Enhanced in the Presence of Hematopoietic TET2 Inactivation.
   Cancer Res. 2026;86:845-857.
   

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6. SHI J, Wang X, Zhang W, Gao Z, et al
   AKT3-Driven Epithelial-Mesenchymal Plasticity Governs Ovarian Metastasis in Colorectal Cancer via Tumor Microenvironment Remodeling.
   Cancer Res. 2026 Feb 9. doi: 10.1158/0008-5472.CAN-25-1718.
   

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7. YUE Z, Dai W, Cao Z, Hu B, et al
   Subcellular Redistribution of Endomembrane GPR15 Promotes NAD+-Mediated Metabolic Reprogramming and Boosts 5-FU Chemosensitivity in Colorectal Cancer.
   Cancer Res. 2026 Feb 9. doi: 10.1158/0008-5472.CAN-25-2586.
   

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8. BANERJEE M, Zaytseva YY, Reusch EM, Napier DL, et al
   FASN Inhibition Enhances the Efficacy of Chemotherapy in Colorectal Cancer by Inhibiting the DNA Damage Response.
   Cancer Res. 2026 Feb 9. doi: 10.1158/0008-5472.CAN-25-1917.
   

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9. LI Q, Zhang Z, Wang Y, Peng X, et al
   ARID1A Mediates SWI/SNF-Independent Maintenance of Heterochromatin Architecture to Restrain Viral Mimicry and Immunogenicity in Colon Cancer.
   Cancer Res. 2026 Feb 9. doi: 10.1158/0008-5472.CAN-25-3231.
   

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10. ZANI F, Blagih J
    Drink Responsibly: Cancer Cells Also Like Sugary Drinks.
    Cancer Res. 2026;86:569-570.
    

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    January 2026
11. YUAN Q, Sun Y, Zhang Y, Chen C, et al
    Intratumoral P. copri Reprograms MARCO+ Tumor-Associated Macrophages by Depleting Glycerophosphocholine to Drive Colorectal Cancer Progression.
    Cancer Res. 2026 Jan 27. doi: 10.1158/0008-5472.CAN-25-3400.
    

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12. KREGER BT, Liang Y, Reilly NM, Spears ME, et al
    CFT1946 Is an Orally Available Brain-Penetrant BRAFV600-Mutant Degrader That Overcomes BRAF Inhibitor Resistance.
    Cancer Res. 2026;86:438-452.
    

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    December 2025
13. DALAL PJ, Shah YM
    Gut Check: Lactobacillus johnsonii Harnesses Bile Acids and Reactive Oxygen Species to Suppress High-Fat Diet-Induced Colorectal Cancer.
    Cancer Res. 2025;85:4579-4581.
    

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14. ARNOUK SM, Kancheva D, Van Damme H, Courtoy GE, et al
    Depleting IL1R2+ Tumor-Infiltrating Regulatory T Cells with an ADCC-Prone Nanobody Construct Boosts the Efficacy of Anti-PD-1 Immunotherapy.
    Cancer Res. 2025;85:4681-4700.
    

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15. ZHAO J, Chen B, Deng Y, Fan L, et al
    ChREBP-Mediated Choline Deprivation and Chemokine Secretion Shape Tumor-Associated Macrophages to Promote Immune Evasion.
    Cancer Res. 2025;85:4701-4717.
    

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    November 2025
16. GILLETTE A, Udgata S, Schmitz AE, Stoecker JN, et al
    Wide-Field Optical Redox Imaging with Leading-Edge Detection Enables Assessment of Treatment Response and Heterogeneity in Patient-Derived Cancer Organoids.
    Cancer Res. 2025;85:4329-4340.
    

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17. MOHAMMAD MIRZAEI N, Hur C, Terry MB, Dalerba P, et al
    Modeling Early-Onset Cancer Kinetics Reveals Changes in Underlying Risk and the Impact of Population Screening.
    Cancer Res. 2025;85:4558-4570.
    

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18. NATTRESS CB, O'Sullivan R, Fowler D, Hutton C, et al
    Phenoscaping Reveals Multimodal gammadelta T-cell Cytotoxicity as a Strategy to Overcome Cancer Cell-Mediated Immunomodulation.
    Cancer Res. 2025;85:4415-4432.
    

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19. FUMET JD, Latour C, Nuttin L, Derangere V, et al
    Tumor-Associated Macrophages Produce PGE2 to Promote CD8+ T Cell Exhaustion and Drive Resistance to PD-L1 Blockade in Microsatellite Stable Colorectal Cancer.
    Cancer Res. 2025 Nov 6. doi: 10.1158/0008-5472.CAN-25-0079.
    

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    October 2025
20. BRUNET GUASCH M, Feeley NA, Soriano I, Thorn S, et al
    Mathematical Modeling Quantifies "Just-Right" APC Inactivation for Colorectal Cancer Initiation.
    Cancer Res. 2025 Oct 15. doi: 10.1158/0008-5472.CAN-25-0445.
    

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21. LI B, Li H, Li Y, Chen Z, et al
    Genetic Control of tRNA-Derived Fragments Contributes to Cancer Risk.
    Cancer Res. 2025;85:3855-3874.
    

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22. LIU S, Zhang Z, Wang Z, Liu C, et al
    SPP1 Drives Colorectal Cancer Liver Metastasis and Immunotherapy Resistance by Stimulating CXCL12 Production in Cancer-Associated Fibroblasts.
    Cancer Res. 2025 Oct 6. doi: 10.1158/0008-5472.CAN-24-4916.
    

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23. SCHATTON D, Frezza C
    Alternatively Spliced Citrate Synthase Supports Colorectal Cancer.
    Cancer Res. 2025 Oct 1:OF1-OF3. doi: 10.1158/0008-5472.CAN-25-3356.
    

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    September 2025
24. MODL B, Zwolanek D, Schwertner K, Krauss D, et al
    TYK2 Promotes Immunosurveillance of Colorectal Cancer Liver Metastasis.
    Cancer Res. 2025 Sep 24. doi: 10.1158/0008-5472.CAN-24-4224.
    

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25. ZHOU M, Liu H, Hui J, Chen Q, et al
    Extracellular Vesicle-Packaged miR-99a Reprograms Fibroblasts to Create an Inflammatory Niche that Drives Colorectal Cancer Metastasis.
    Cancer Res. 2025 Sep 24. doi: 10.1158/0008-5472.CAN-25-0663.
    

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26. SUN F, Wang K, Dong X, Secaira-Morocho H, et al
    The Microbial Bile Acid Metabolite 3-oxo-LCA Inhibits Colorectal Cancer Progression.
    Cancer Res. 2025 Sep 16. doi: 10.1158/0008-5472.CAN-24-3898.
    

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27. LIU C, Lai P, Hu J, Yin S, et al
    Lactobacillus johnsonii Synthesizes Chenodeoxycholic Acid to Reduce Susceptibility to High-Fat Diet-Induced Colorectal Cancer.
    Cancer Res. 2025 Sep 15. doi: 10.1158/0008-5472.CAN-25-0879.
    

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28. CHEUNG JCT, Ng LW, Zhu Z, Chen B, et al
    A Citrate Synthase Splice Variant Rewires the TCA Cycle to Promote Colorectal Cancer Progression.
    Cancer Res. 2025 Sep 3. doi: 10.1158/0008-5472.CAN-24-2355.
    

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    August 2025
29. ZHOU HM, Liu Y, Shi F, Qiu HW, et al
    CLK2 Regulates the KEAP1/NRF2 and p53 Pathways to Suppress Ferroptosis in Colorectal Cancer.
    Cancer Res. 2025 Aug 29. doi: 10.1158/0008-5472.CAN-24-4949.
    

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30. ZHENG Z, Yuan F, Li J, Zhu X, et al
    Gut Microbiota-Mediated Bile Acid Metabolism Regulates Colorectal Cancer Liver Metastasis by Altering Neutrophil Recruitment.
    Cancer Res. 2025 Aug 27. doi: 10.1158/0008-5472.CAN-24-4425.
    

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31. SHORT SP
    Ferreting Out Ferroptosis: Extending the Mechanism of Action of RSL3 to the Selenoproteome in Colorectal Cancer.
    Cancer Res. 2025;85:2775-2777.
    

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32. OLIVEIRA EA, Milite S, Fernandez-Mateos J, Cresswell GD, et al
    Epigenetic Heritability of Cell Plasticity Drives Cancer Drug Resistance through a One-to-Many Genotype-to-Phenotype Paradigm.
    Cancer Res. 2025;85:2921-2938.
    

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    May 2025
33. DEANGELO SL, Zhao L, Dziechciarz S, Shin M, et al
    Recharacterization of the Tumor Suppressive Mechanism of RSL3 Identifies the Selenoproteome as a Druggable Pathway in Colorectal Cancer.
    Cancer Res. 2025 May 20. doi: 10.1158/0008-5472.CAN-24-3478.
    

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34. MATEJCIC M, Teer JK, Hoehn HJ, Diaz DB, et al
    Colorectal Tumors in Diverse Patient Populations Feature a Spectrum of Somatic Mutational Profiles.
    Cancer Res. 2025;85:1928-1944.
    

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35. BUCKENMEYER MJ, Brooks EA, Taylor MS, Orenuga IK, et al
    A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates In Vivo Tumor Phenotypes and Heterogeneity.
    Cancer Res. 2025;85:1577-1595.
    

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    March 2025
36. TIKUM AF, Henning NW, Pougoue Ketchemen J, Doroudi A, et al
    An Anti-EGFR Antibody-Drug Radioconjugate Labeled with Actinium-225 Elicits Durable Anti-Tumor Responses in KRAS and BRAF Mutant Colorectal Cancer.
    Cancer Res. 2025 Mar 24. doi: 10.1158/0008-5472.CAN-24-2266.
    

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    February 2025
37. LIN Y, Zhang Y, Huang T, Chen J, et al
    Arginine Deprivation Induces Quiescence and Confers Vulnerability to Ferroptosis in Colorectal Cancer.
    Cancer Res. 2025 Feb 24. doi: 10.1158/0008-5472.CAN-24-1940.
    

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38. DENG S, Wang J, Zou F, Cheng D, et al
    Palmitic Acid Accumulation Activates Fibroblasts and Promotes Matrix Stiffness in Colorectal Cancer.
    Cancer Res. 2025 Feb 24. doi: 10.1158/0008-5472.CAN-24-2892.
    

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39. XU J, Meng Q, Li X, Yang H, et al
    Correction: Long Noncoding RNA MIR17HG Promotes Colorectal Cancer Progression via miR-17-5p.
    Cancer Res. 2025;85:826.
    

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40. CASTRO J, Daniels MH, Brennan D, Johnston B, et al
    A Potent, Selective, Small-Molecule Inhibitor of DHX9 Abrogates Proliferation of Microsatellite Instable Cancers with Deficient Mismatch Repair.
    Cancer Res. 2025;85:758-776.
    

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    January 2025
41. LI D, Liu X, Gao W, Zhao W, et al
    An Immune Subtype Classification System Enables the Development of Strategies to Predict and Enhance Immunotherapy Responses in Colorectal Cancer.
    Cancer Res. 2025 Jan 29. doi: 10.1158/0008-5472.CAN-24-2464.
    

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42. KALLIO P, Bessone C, Seyednasrollah F, Brodkin J, et al
    A Multipotent PROX1+ Tumor Stem/Progenitor Cell Population Emerges During Intestinal Tumorigenesis and Mediates Radioresistance in Colorectal Cancer.
    Cancer Res. 2025 Jan 22. doi: 10.1158/0008-5472.CAN-23-1851.
    

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    December 2024
43. JACOB J, Anami Y, High PC, Liang Z, et al
    Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer.
    Cancer Res. 2024 Dec 18. doi: 10.1158/0008-5472.CAN-24-0798.
    

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44. CUI L, Liu R, Han S, Zhang C, et al
    Targeting Arachidonic Acid Metabolism Enhances Immunotherapy Efficacy in ARID1A-Deficient Colorectal Cancer.
    Cancer Res. 2024 Dec 9. doi: 10.1158/0008-5472.CAN-24-1611.
    

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45. GUO X, Luo S, Wang X, Cui Y, et al
    CD24-Targeted NIR-II Fluorescence Imaging Enables Early Detection of Colorectal Neoplasia.
    Cancer Res. 2024;84:4099-4113.
    

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    October 2024
46. CHUA J, Gregorieff A, Ayyaz A
    Bottom-up or Top-down: Inflammation Reprograms Paneth Cells to Develop Bowel Cancers.
    Cancer Res. 2024;84:3324-3326.
    

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47. LADAIKA CA, Ghobashi AH, Boulton WC, Miller SA, et al
    LSD1 and CoREST2 Potentiate STAT3 Activity to Promote Enteroendocrine Cell Differentiation in Mucinous Colorectal Cancer.
    Cancer Res. 2024 Oct 4. doi: 10.1158/0008-5472.CAN-24-0788.
    

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48. ROLFO C, Russo A
    The Next Frontier for Colorectal Cancer Screening: Blood-Based Tests.
    Cancer Res. 2024;84:3128-3129.
    

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    September 2024
49. WANG H, Chen J, Chen X, Liu Y, et al
    Cancer-Associated Fibroblasts Expressing Sulfatase 1 Facilitate VEGFA-Dependent Microenvironmental Remodeling to Support Colorectal Cancer.
    Cancer Res. 2024 Sep 9. doi: 10.1158/0008-5472.CAN-23-3987.
    

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50. CHEN D, Ji F, Zhou Q, Cheung H, et al
    RUVBL1/2 Blockade Targets YTHDF1 Activity to Suppress m6A-Dependent Oncogenic Translation and Colorectal Tumorigenesis.
    Cancer Res. 2024;84:2856-2872.
    

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51. SHU Y, Jin X, Ji M, Zhang Z, et al
    Ku70 Binding to YAP Alters PARP1 Ubiquitination to Regulate Genome Stability and Tumorigenesis.
    Cancer Res. 2024;84:2836-2855.
    

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    August 2024
52. SAHA S, Ghosh M, Li J, Wen A, et al
    Serine Depletion Promotes Antitumor Immunity by Activating Mitochondrial DNA-Mediated cGAS-STING Signaling.
    Cancer Res. 2024;84:2645-2659.
    

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    July 2024
53. CAO Y, Wang N, Wu X, Tang W, et al
    Multi-Dimensional Fragmentomics Enables Early and Accurate Detection of Colorectal Cancer.
    Cancer Res. 2024 Jul 29. doi: 10.1158/0008-5472.CAN-23-3486.
    

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54. LIAO S, Deng J, Deng M, Chen C, et al
    AFDN deficiency promotes liver tropism of metastatic colorectal cancer.
    Cancer Res. 2024 Jul 24. doi: 10.1158/0008-5472.CAN-23-3140.
    

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    June 2024
55. LI L, Jiang D, Liu H, Guo C, et al
    Comprehensive Proteogenomic Profiling Reveals the Molecular Characteristics of Colorectal Cancer at Distinct Stages of Progression.
    Cancer Res. 2024 Jun 11. doi: 10.1158/0008-5472.CAN-23-1878.
    

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    May 2024
56. BAKER AM, Nageswaran G, Nenclares P, Ronel T, et al
    FUME-TCRseq Enables Sensitive and Accurate Sequencing of the T-cell Receptor from Limited Input of Degraded RNA.
    Cancer Res. 2024;84:1560-1569.
    

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57. BAHRAMBEIGI V, Lee JJ, Branchi V, Rajapakshe KI, et al
    Transcriptomic Profiling of Plasma Extracellular Vesicles Enables Reliable Annotation of the Cancer-Specific Transcriptome and Molecular Subtype.
    Cancer Res. 2024;84:1719-1732.
    

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    April 2024
58. YANG S, Zhang D, Sun Q, Nie H, et al
    Single-Cell and Spatial Transcriptome Profiling Identifies the Transcription Factor BHLHE40 as a Driver of EMT in Metastatic Colorectal Cancer.
    Cancer Res. 2024 Apr 24. doi: 10.1158/0008-5472.CAN-23-3264.
    

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59. ZHAO N, Cao Y, Tao R, Zhu X, et al
    The circMYBL2-encoded p185 protein suppresses colorectal cancer progression by inhibiting serine biosynthesis.
    Cancer Res. 2024 Apr 18. doi: 10.1158/0008-5472.CAN-23-2940.
    

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60. CHEN Y, Ying Y, Ma W, Ma H, et al
    Targeting the Epigenetic Reader ENL Inhibits Super-Enhancer-Driven Oncogenic Transcription and Synergizes with BET Inhibition to Suppress Tumor Progression.
    Cancer Res. 2024;84:1237-1251.
    

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    March 2024
61. MCCOLLUM SE, Shah YM
    Stressing Out Cancer: Chronic Stress Induces Dysbiosis and Enhances Colon Cancer Growth.
    Cancer Res. 2024;84:645-647.
    

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62. FANG L, Zhang L, Wang M, He Y, et al
    Pooled CRISPR Screening Identifies P-Bodies as Repressors of Cancer Epithelial-Mesenchymal Transition.
    Cancer Res. 2024;84:659-674.
    

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    October 2023
63. GARCIA-RODRIGUEZ JL, Korsgaard U, Ahmadov U, Jarlstad Olesen MT, et al
    Spatial Profiling of Circular RNAs in Cancer Reveals High Expression in Muscle and Stromal Cells.
    Cancer Res. 2023;83:3340-3353.
    

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