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Articles published in
Cancer Lett
    October 2025
  1. GUO Z, He L, Wang W, Tian S, et al
    Corrigendum to "FUT2-dependent fucosylation of LAMP1 promotes the apoptosis of colorectal cancer cells by regulating theautophagy-lysosomal pathway" [Cancer Lett. (2025) 619 217643].
    Cancer Lett. 2025 Oct 3:217981. doi: 10.1016/j.canlet.2025.217981.
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    September 2025
  2. BAI F, Liao L, Tang Y, Wu Y, et al
    RCMIX model based on pre-treatment MRI imaging predicts T-downstage in MRI-cT4 stage rectal cancer.
    Cancer Lett. 2025;628:217871.
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  3. SUN L, Gao X, Wang M, Zhang Y, et al
    Gobal crotonylome reveals that HNRNPC and its crotonylation promote p53-deficient tumor growth by stabilizing CCND1 and MCM3 mRNAs.
    Cancer Lett. 2025;628:217854.
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  4. BAI M, Li N, Yin X, Huang C, et al
    An anti-PD-1 antibody (SCT-I10A) plus anti-EGFR antibody (SCT200) and chemotherapy for RAS/BRAF wild-type metastatic colorectal cancer: A phase Ib study.
    Cancer Lett. 2025 Sep 24:218061. doi: 10.1016/j.canlet.2025.218061.
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  5. YIN Z, Zhou Y, Zhu X, Goettl RA, et al
    Cancer-associated fibroblast secreted DKK1 promotes the immunosuppressive tumor microenvironment and colorectal cancer resistance to chemotherapy.
    Cancer Lett. 2025 Sep 24:218060. doi: 10.1016/j.canlet.2025.218060.
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    August 2025
  6. HORN DM, Phillips KA, Schulman KA
    Comparison of Food and Drug Administration Expedited Approvals and Guideline Updates: A Case Study of Immune Checkpoint Inhibitors in Colon Cancer Care.
    Cancer Lett. 2025 Aug 12:217979. doi: 10.1016/j.canlet.2025.217979.
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  7. SUN Z, Wu R, Liang X, Shi T, et al
    MLCK inhibition induces synthetic lethality in MYC-driven cancer.
    Cancer Lett. 2025;625:217803.
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  8. TSAI HY, Chen MH, Yun J, Lai LA, et al
    Restricting metabolic plasticity enhances stress adaptation through the modulation of PDH and HIF1A in TRAP1-depleted colon cancer.
    Cancer Lett. 2025 Aug 9:217977. doi: 10.1016/j.canlet.2025.217977.
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  9. ZOU H, Liu Y, Yang X, Zhang Q, et al
    PRMT2 promotes tumorigenic phenotypes through the Wnt signaling pathway and drives immune suppression in Colorectal cancer.
    Cancer Lett. 2025 Aug 4:217967. doi: 10.1016/j.canlet.2025.217967.
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    July 2025
  10. MORGAN R, Bayat Tork MA, Lin Z, Wild C, et al
    High-Fat Diet Driven Post-Operative Colon Cancer Recurrence is Dependent upon Genetic Susceptibility to Deoxycholic Acid.
    Cancer Lett. 2025 Jul 22:217943. doi: 10.1016/j.canlet.2025.217943.
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  11. HAN S, Chen Z, Hong C, Dang T, et al
    Inhibition of KAT6A Enhances Immunotherapy Efficacy in Colorectal Cancer by Activating Interferon Response.
    Cancer Lett. 2025 Jul 22:217946. doi: 10.1016/j.canlet.2025.217946.
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  12. WANG H, Du S, Ji S, Miao G, et al
    SMARCA1-NPFF axis inhibits colorectal cancer metastasis by blocking epithelial-mesenchymal transition and macrophage-dependent immune reprogramming.
    Cancer Lett. 2025;631:217933.
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  13. HAN Y, Xu X, Peng Y, Zhu J, et al
    CircFLNB upregulated by chemotherapy via alternative splicing suppresses the progression of colorectal cancer.
    Cancer Lett. 2025;631:217932.
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  14. HE J, Li W, Wang S, Lan J, et al
    Cancer associated fibroblasts-derived lactate induces oxaliplatin treatment resistance by promoting cancer stemness via ANTXR1 lactylation in colorectal cancer.
    Cancer Lett. 2025;631:217917.
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  15. BIRGERSSON M, Holm M, Gallardo-Dodd CJ, Chen B, et al
    Intestinal estrogen receptor beta modulates the murine colon tumor immune microenvironment.
    Cancer Lett. 2025;622:217661.
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  16. DANEK V, Tureckova J, Huebner K, Erlenbach-Wuensch K, et al
    CUL4A exhibits tumor-suppressing role via regulation of HUWE1-mediated SMAD3 intracellular shuttling.
    Cancer Lett. 2025;621:217663.
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    June 2025
  17. GERAKOPOULOS V, Ramos C, Muller C, Walterskirchen N, et al
    Single-cell transcriptomic analysis identifies tissue-specific fibroblasts as the main modulators of myeloid cells in peritoneal metastasis of different origin.
    Cancer Lett. 2025;620:217678.
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  18. KHAN S, Karmokar A, Howells L, Britton RG, et al
    An old spice with new tricks: Curcumin targets adenoma and colorectal cancer stem-like cells associated with poor survival outcomes.
    Cancer Lett. 2025 Jun 19:217885. doi: 10.1016/j.canlet.2025.217885.
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  19. YU C, Lu W, Wu J, Fang X, et al
    Liver metastasis or peritoneal metastasis: single-cell RNA sequencing reveals the organotropism in colorectal cancer is driven by distinct partial-EMT processes.
    Cancer Lett. 2025 Jun 17:217880. doi: 10.1016/j.canlet.2025.217880.
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    May 2025
  20. MIDDE A, Arri N, Kristian T, Mukherjee S, et al
    Corrigendum to "Targeting mitochondrial ribosomal protein expression by andrographolide and melatonin for colon cancer treatment" [Cancer Lett. 619 (2025) 1-11 217647].
    Cancer Lett. 2025 May 30:217784. doi: 10.1016/j.canlet.2025.217784.
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  21. ZHOU M, Guan B, Liu Y, Gu Q, et al
    Fibrinogen-like 2 in tumor-associated macrophage-derived extracellular vesicles shapes an immunosuppressive microenvironment in colorectal liver metastases by promoting tumor stemness and neutrophil extracellular traps formation.
    Cancer Lett. 2025;618:217642.
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  22. SUN Y, Lu J, Tung Lau EY, Zeng Y, et al
    Fusobacterium nucleatum enhances cholesterol biosynthesis in colorectal cancer via miR-130a-3p-mediated AMPK inhibition, a process counteracted by butyrate.
    Cancer Lett. 2025 May 23:217810. doi: 10.1016/j.canlet.2025.217810.
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  23. CHEN X, Cao Y, Zhao Y, Ma Y, et al
    Neurodegeneration of local sympathetic inputs promotes colorectal cancer progression.
    Cancer Lett. 2025;625:217817.
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  24. HU D, Zhao J, Wu M, Zhou Y, et al
    Microbial Interactions Induce the Mutational Signature of Mismatch Repair Deficiency in Colorectal Cancer and Associated with EPPK1 Mutations.
    Cancer Lett. 2025 May 16:217807. doi: 10.1016/j.canlet.2025.217807.
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  25. HE K, Wang H, Wu H, Li W, et al
    Activated Schwann cells promote tumor growth in colon cancer.
    Cancer Lett. 2025;626:217791.
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  26. LU YX, Ju HQ, Wang F, Chen LZ, et al
    Corrigendum to "Inhibition of the NF-kappaB pathway by nafamostat mesilate suppresses colorectal cancer growth and metastasis" [Cancer Lett. 380 (2016) 87-97].
    Cancer Lett. 2025;625:217756.
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  27. STRIPPOLI R
    Colorectal cancer peritoneal metastasis is promoted by tissue-specific fibroblasts that can arise in response to various local disorders.
    Cancer Lett. 2025;625:217749.
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  28. ZHOU XY, Zhang NC, Zhang XN, Sun XD, et al
    The carcinogenic metabolite acetaldehyde impairs cGAS activity to negatively regulate antiviral and antitumor immunity.
    Cancer Lett. 2025;617:217615.
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    April 2025
  29. ZHONG YX, Zhao HB, Lian MH, Shen JM, et al
    SUMOylated hnRNPM suppresses PFKFB3 phosphorylation to regulate glycolysis and tumorigenesis.
    Cancer Lett. 2025;616:217573.
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  30. RAMOS C, Walterskirchen N, Knobl V, Zotter C, et al
    Colorectal cancer peritoneal metastasis is promoted by tissue-specific fibroblasts that can arise in response to various local disorders.
    Cancer Lett. 2025 Apr 12:217686. doi: 10.1016/j.canlet.2025.217686.
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  31. HOLDFELDT A, Salerno S, Stahlberg A, Lindskog EB, et al
    The colorectal cancer microenvironment governs clinical behaviors and chemotherapy response.
    Cancer Lett. 2025 Apr 1:217687. doi: 10.1016/j.canlet.2025.217687.
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    March 2025
  32. RICHIARDONE E, Giolito MV, Al Roumi R, Ambroise J, et al
    Acidosis overrides molecular heterogeneity to shape therapeutically targetable metabolic phenotypes in colon cancers.
    Cancer Lett. 2025;613:217512.
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  33. GU Y, Ye Q, Huang X, Cao Y, et al
    Glycosaminoglycan modification of NRP1 exon 4-skipping variant drives colorectal cancer metastasis via endosomal-exosomal trafficking.
    Cancer Lett. 2025 Mar 27:217683. doi: 10.1016/j.canlet.2025.217683.
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  34. MIDDE A, Arri N, Kristian T, Mukherjee S, et al
    Targeting mitochondrial ribosomal protein expression by andrographolide and melatonin for colon cancer treatment.
    Cancer Lett. 2025;619:217647.
    >> Share

  35. LI M, Gao X, Lin X, Zhang Y, et al
    Analysis of germline-somatic mutational connections in colorectal cancer reveals differential tumorigenic patterns and a novel predictive marker for germline mutation carriers.
    Cancer Lett. 2025 Mar 19:217637. doi: 10.1016/j.canlet.2025.217637.
    >> Share

  36. GUO Z, He L, Wang W, Tian S, et al
    FUT2-dependent fucosylation of LAMP1 promotes the apoptosis of colorectal cancer cells by regulating the autophagy-lysosomal pathway.
    Cancer Lett. 2025 Mar 18:217643. doi: 10.1016/j.canlet.2025.217643.
    >> Share

  37. YAO L, Yin H, Yang C, Han S, et al
    GENERATING RESEARCH HYPOTHESES TO OVERCOME KEY CHALLENGES IN THE EARLY DIAGNOSIS OF COLORECTAL CANCER - FUTURE APPLICATION OF AI.
    Cancer Lett. 2025 Mar 15:217632. doi: 10.1016/j.canlet.2025.217632.
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    February 2025
  38. LOPES AL, Paulino AC, Thaumaturgo MAS, Araujo WM, et al
    Dietary intake of the red meat-derived glycan Neu5Gc fuels colorectal cancer through up-regulation of Wnt signaling pathway.
    Cancer Lett. 2025;616:217598.
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  39. BAI M, Jin Y, Jin Z, Xie Y, et al
    Distinct Immunophenotypic Profiles and Neutrophil Heterogeneity in Colorectal Cancer.
    Cancer Lett. 2025 Feb 22:217570. doi: 10.1016/j.canlet.2025.217570.
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  40. WANG T, Weng M, Li K, Li G, et al
    LIN28B enhances the chemosensitivity of colon cancer cells via inducing genomic instability by upsetting the balance between the production and removal of reactive oxygen species.
    Cancer Lett. 2025 Feb 20:217572. doi: 10.1016/j.canlet.2025.217572.
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  41. ZHUO FF, Li L, Liu TT, Liang XM, et al
    Corrigendum to "Lycorine promotes IDH1 acetylation to induce mitochondrial dynamics imbalance in colorectal cancer cells" [Canc. Lett. 573 (2023) 216364].
    Cancer Lett. 2025 Feb 9:217533. doi: 10.1016/j.canlet.2025.217533.
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    January 2025
  42. BAI X, Liu B, Fan D, Lu Y, et al
    Modulating the gut microbiota: A novel perspective in colorectal cancer treatment.
    Cancer Lett. 2025 Jan 11:217459. doi: 10.1016/j.canlet.2025.217459.
    >> Share

  43. ZHAN Y, Sun D, Gao J, Gao Q, et al
    Single-cell Transcriptomics Reveals Intratumor Heterogeneity and the Potential Roles of Cancer Stem Cells and myCAFs in Colorectal Cancer Liver Metastasis and Recurrence.
    Cancer Lett. 2025 Jan 11:217452. doi: 10.1016/j.canlet.2025.217452.
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    December 2024
  44. XU C, Jiang C, Tian Y, Liu Y, et al
    Nervous system in colorectal cancer.
    Cancer Lett. 2024 Dec 24:217431. doi: 10.1016/j.canlet.2024.217431.
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  45. ZHOU Y, Lei T, Tang Z, Guo P, et al
    Increased phosphorylation of AMPKalpha1 S485 in colorectal cancer and identification of PKCalpha as a responsible kinase.
    Cancer Lett. 2024 Dec 24:217418. doi: 10.1016/j.canlet.2024.217418.
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  46. MALIER M, Laverriere MH, Henry M, Yakoubi M, et al
    Tumor-associated macrophages confer resistance to chemotherapy (Trifluridine/Tipiracil) in digestive cancers by overexpressing thymidine phosphorylase.
    Cancer Lett. 2024;606:217307.
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    November 2024
  47. DONG Z, Ojha A, Barlow L, Luo L, et al
    The eIF3a translational control axis in the Wnt/beta-catenin signaling pathway and colon tumorigenesis.
    Cancer Lett. 2024;605:217303.
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  48. O'BRIEN RM, Meltzer S, Buckley CE, Heeran AB, et al
    Complement is increased in treatment resistant rectal cancer and modulates radioresistance.
    Cancer Lett. 2024;604:217253.
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  49. YAO B, Wu J
    Letter to the editor on 'A deep neural network predictor to predict the sensitivity of neoadjuvant chemoradiotherapy in locally advanced rectal cancer'.
    Cancer Lett. 2024;604:217212.
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    September 2024
  50. TAN YT, Li T, Wang RB, Liu ZK, et al
    WTAP weakens oxaliplatin chemosensitivity of colorectal cancer by preventing PANoptosis.
    Cancer Lett. 2024;604:217254.
    >> Share

  51. YANG H, Gong C, Wu Y, Xie X, et al
    LncRNA SNHG1 facilitates colorectal cancer cells metastasis by recruiting HNRNPD protein to stabilize SERPINA3 mRNA.
    Cancer Lett. 2024 Sep 2:217217. doi: 10.1016/j.canlet.2024.217217.
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    August 2024
  52. LI M, Xie Y, Zhang J, Zhou X, et al
    Intratumoral injection of mRNA encoding survivin in combination with STAT3 inhibitor stattic enhances antitumor effects.
    Cancer Lett. 2024;598:217111.
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  53. ZHOU L, Wen R, Bai C, Li Z, et al
    Spatial transcriptomic revealed intratumor heterogeneity and cancer stem cell enrichment in colorectal cancer metastasis.
    Cancer Lett. 2024 Aug 17:217181. doi: 10.1016/j.canlet.2024.217181.
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  54. HAN Y, Pu Y, Liu X, Liu Z, et al
    YTHDF1 regulates GID8-mediated glutamine metabolism to promote colorectal cancer progression in a m6A-dependent manner.
    Cancer Lett. 2024 Aug 14:217186. doi: 10.1016/j.canlet.2024.217186.
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  55. LING T, Dai Z, Wang H, Kien TT, et al
    Serotonylation in tumor-associated fibroblasts contributes to the tumor-promoting roles of serotonin in colorectal cancer.
    Cancer Lett. 2024 Aug 1:217150. doi: 10.1016/j.canlet.2024.217150.
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    July 2024
  56. KONG WS, Li JJ, Deng YQ, Ju HQ, et al
    Immunomodulatory molecules in colorectal cancer liver metastasis.
    Cancer Lett. 2024;598:217113.
    >> Share

  57. ZHU N, Ding Y, Mi M, Yang J, et al
    Loss-of-function mutation of REV1 (p.R704Q) mediates cetuximab primary resistance by activating autophagy in RAS-wild type metastatic colorectal cancer.
    Cancer Lett. 2024 Jul 3:217103. doi: 10.1016/j.canlet.2024.217103.
    >> Share

  58. LUO XJ, Lu YX, Wang Y, Huang R, et al
    M6A-modified lncRNA FAM83H-AS1 promotes colorectal cancer progression through PTBP1.
    Cancer Lett. 2024 Jul 2:217085. doi: 10.1016/j.canlet.2024.217085.
    >> Share

  59. RICHIARDONE E, Al Roumi R, Lardinois F, Giolito MV, et al
    MCT1-dependent lactate recycling is a metabolic vulnerability in colorectal cancer cells upon acquired resistance to anti-EGFR targeted therapy.
    Cancer Lett. 2024 Jul 2:217091. doi: 10.1016/j.canlet.2024.217091.
    >> Share

  60. CHEN Q, Chen J, Deng Y, Bi X, et al
    Personalized prediction of postoperative complication and survival among Colorectal Liver Metastases Patients Receiving Simultaneous Resection using machine learning approaches: A multi-center study.
    Cancer Lett. 2024;593:216967.
    >> Share

  61. HUANG C, Tan H, Wang J, Huang L, et al
    beta-hydroxybutyrate restrains colitis-associated tumorigenesis by inhibiting HIF-1alpha-mediated angiogenesis.
    Cancer Lett. 2024;593:216940.
    >> Share

    June 2024
  62. HANG D, Sun D, Du L, Huang J, et al
    Development and evaluation of a risk prediction tool for risk-adapted screening of colorectal cancer in China.
    Cancer Lett. 2024;597:217057.
    >> Share

  63. YUAN M, Zhang C, Chen S, Ye S, et al
    PDP1 promotes KRAS mutant colorectal cancer progression by serving as a scaffold for BRAF and MEK1.
    Cancer Lett. 2024;597:217007.
    >> Share

  64. BIAN Y, Xu S, Gao Z, Ding J, et al
    m(6)A modification of lncRNA ABHD11-AS1 promotes colorectal cancer progression and inhibits ferroptosis through TRIM21/IGF2BP2/ FOXM1 positive feedback loop.
    Cancer Lett. 2024 Jun 3:217004. doi: 10.1016/j.canlet.2024.217004.
    >> Share

    May 2024
  65. AGORKU DJ, Bosio A, Alves F, Strobel P, et al
    Colorectal cancer-associated fibroblasts inhibit effector T cells via NECTIN2 signaling.
    Cancer Lett. 2024;595:216985.
    >> Share

  66. LUN J, Zhang Y, Yu M, Zhai W, et al
    Circular RNA circHIPK2 inhibits colon cancer cells through miR-373-3p/RGMA axis.
    Cancer Lett. 2024;593:216957.
    >> Share

  67. LIU Y, Shi J, Liu W, Tang Y, et al
    A deep neural network predictor to predict the sensitivity of neoadjuvant chemoradiotherapy in locally advanced rectal cancer.
    Cancer Lett. 2024;589:216641.
    >> Share

    April 2024
  68. YANG Y, Qi J, Hu J, Zhou Y, et al
    Lovastatin/SN38 co-loaded liposomes amplified ICB therapeutic effect via remodeling the immunologically-cold colon tumor and synergized stimulation of cGAS-STING pathway.
    Cancer Lett. 2024;588:216765.
    >> Share

  69. JIN Y, Jiang J, Mao W, Bai M, et al
    Treatment strategies and molecular mechanism of radiotherapy combined with immunotherapy in colorectal cancer.
    Cancer Lett. 2024;591:216858.
    >> Share

  70. ZHOU X, Zhang K, Wang C, Teng Y, et al
    Isthmin-1 promotes growth and progression of colorectal cancer through the interaction with EGFR and YBX-1.
    Cancer Lett. 2024 Apr 7:216868. doi: 10.1016/j.canlet.2024.216868.
    >> Share

  71. JIANG C, Zhou Q, Yi K, Yuan Y, et al
    Colorectal cancer initiation: Understanding early-stage disease for intervention.
    Cancer Lett. 2024 Apr 2:216831. doi: 10.1016/j.canlet.2024.216831.
    >> Share

    March 2024
  72. ZHOU Y, Li H, Zhang Y, Zhao E, et al
    Deubiquitinase USP4 suppresses antitumor immunity by inhibiting IRF3 activation and tumor cell-intrinsic interferon response in colorectal cancer.
    Cancer Lett. 2024 Mar 29:216836. doi: 10.1016/j.canlet.2024.216836.
    >> Share

  73. LIN J, Zhong W, Lyu Z, Peng J, et al
    Circular RNA circTATDN3 promotes the Warburg effect and proliferation in colorectal cancer.
    Cancer Lett. 2024 Mar 26:216825. doi: 10.1016/j.canlet.2024.216825.
    >> Share

  74. ZHANG D, Xie J, Sun F, Xu R, et al
    Pharmacological suppression of HHLA2 glycosylation restores anti-tumor immunity in colorectal cancer.
    Cancer Lett. 2024 Mar 22:216819. doi: 10.1016/j.canlet.2024.216819.
    >> Share

  75. HISANO K, Mizuuchi Y, Ohuchida K, Kawata J, et al
    Microenvironmental changes in familial adenomatous polyposis during colorectal cancer carcinogenesis.
    Cancer Lett. 2024;589:216822.
    >> Share

  76. ZHU Z, Li M, Weng J, Li S, et al
    LncRNA GAS6-AS1 contributes to 5-fluorouracil resistance in colorectal cancer by facilitating the binding of PCBP1 with MCM3.
    Cancer Lett. 2024 Mar 21:216828. doi: 10.1016/j.canlet.2024.216828.
    >> Share

  77. TANG Y, Wei J, Ge X, Yu C, et al
    Intratumoral injection of interferon gamma promotes the efficacy anti-PD1 treatment in colorectal cancer.
    Cancer Lett. 2024 Mar 9:216798. doi: 10.1016/j.canlet.2024.216798.
    >> Share

  78. CHEN Q, Deng Y, Li Y, Chen J, et al
    Association of preoperative aspartate aminotransferase to platelet ratio index with outcomes and tumour microenvironment among colorectal cancer with liver metastases.
    Cancer Lett. 2024 Mar 6:216778. doi: 10.1016/j.canlet.2024.216778.
    >> Share

    January 2024
  79. LIU C, Cheng X, Han K, Hong L, et al
    A novel molecular subtyping based on multi-omics analysis for prognosis predicting in colorectal melanoma: A 16-year prospective multicentric study.
    Cancer Lett. 2024 Jan 19:216663. doi: 10.1016/j.canlet.2024.216663.
    >> Share


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