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Cancer Res
    March 2026
  1. WANG C, Sun T, He Y, Yu M, et al
    A Deep Learning-Driven Framework Integrating Organoid-Based Functional Validation Identifies Universal Neoantigens from Recurrent Glioma Mutations.
    Cancer Res. 2026 Mar 26. doi: 10.1158/0008-5472.CAN-25-2679.
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  2. ALVARO-ESPINOSA L, Marquez-Galera A, Priego N, Garcia-Calvo V, et al
    MIF-Induced CD74+ Microglia and Macrophages Promote Progression of Brain Metastasis and are Clinically Relevant Across Central Nervous System Disorders.
    Cancer Res. 2026 Mar 24. doi: 10.1158/0008-5472.CAN-25-4018.
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  3. VALLEBUONA EJ, Smalley I
    Spatially Resolved Opto-Omics Uncovers Functional Microglial Subtypes in Brain Metastasis.
    Cancer Res. 2026;86:1345-1346.
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  4. TSUJI T, Hirose H, Sugiyama D, Shindo M, et al
    Microglia Display Heterogeneous Initial Responses to Disseminated Tumor Cells.
    Cancer Res. 2026;86:1414-1434.
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    February 2026
  5. JUNTTILA MR, Repellin CE, Salaniwal S, Warne R, et al
    Enozertinib Is a Selective, Brain-Penetrant EGFR Inhibitor for Treating Non-Small Cell Lung Cancers with EGFR Exon 20 and Atypical Mutations.
    Cancer Res. 2026;86:759-772.
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    January 2026
  6. NAH GSS, Chong YK, Sulaimi FN, Lee KL, et al
    ETC-501 is a Brain Penetrant MNK Kinase Inhibitor that Potentiates TMZ-Induced Senescence and Sensitizes Glioblastoma Cells to Senolytic Therapy.
    Cancer Res. 2026 Jan 22. doi: 10.1158/0008-5472.CAN-24-4388.
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  7. KREGER BT, Liang Y, Reilly NM, Spears ME, et al
    CFT1946 Is an Orally Available Brain-Penetrant BRAFV600-Mutant Degrader That Overcomes BRAF Inhibitor Resistance.
    Cancer Res. 2026;86:438-452.
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  8. SCHUFTAN E, Lu IN, de Faria FW, Inserte C, et al
    Integrated Single-Nucleus and Spatial Transcriptomics Elucidate Heterogeneity and Hypoxia-Driven Organization of Supratentorial Ependymoma.
    Cancer Res. 2026;86:540-555.
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  9. KRATTLI RP JR, Do AH, El-Khatib SM, Alikhani L, et al
    C5aR1 Inhibition Alleviates Cranial Radiation-Induced Cognitive Decline.
    Cancer Res. 2026;86:255-272.
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    December 2025
  10. RIVERA-CARABALLO KA, Lee TJ, Sinha A, Orecchioni M, et al
    Oncolytic HSV-1-Mediated JAG1 Blockade Induces Glioma Senescence-Associated Secretory Phenotype to Increase Macrophage Activation and Cetuximab-Mediated Senolysis.
    Cancer Res. 2025 Dec 18. doi: 10.1158/0008-5472.CAN-25-1402.
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  11. XIA Z, Liu W, Guo D, Chen L, et al
    circADAMTS12 Inhibits the Antitumor Activity of Microglia to Enable Metastatic Colonization in the Brain.
    Cancer Res. 2025;85:4977-4994.
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    November 2025
  12. GANGWANI K, Lu C, Dhanda SK, Sioson E, et al
    The Medulloblastoma Meta-Analysis Portal Enables Integrative Exploration of Clinical and Genomic Data from Patients.
    Cancer Res. 2025 Nov 5:OF1-OF9. doi: 10.1158/0008-5472.CAN-24-4976.
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    October 2025
  13. KIM KW, Choi HJ, Lee JH
    White matter injury fuels early progression of glioblastoma.
    Cancer Res. 2025 Oct 1. doi: 10.1158/0008-5472.CAN-25-4362.
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    September 2025
  14. KHAN F, Petrosyan E, Liu Y, Bahrami A, et al
    Microglial TBK1 Signaling Promotes Breast Cancer Brain Metastasis.
    Cancer Res. 2025 Sep 18. doi: 10.1158/0008-5472.CAN-25-1791.
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  15. CUI Y, Phuong K, Abdelfattah NS, Temple HM, et al
    Quantitative Cell Type Specific Immunopeptidome Analysis of Macrophage and Tumor Co-evolution Reveals Therapeutic MHC-I Peptides in Glioblastoma.
    Cancer Res. 2025 Sep 18. doi: 10.1158/0008-5472.CAN-24-4674.
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  16. AHN JY, Dong W, Puri A, Vasquez M, et al
    Spatial Crosstalk Modeling of the Tumor Microenvironment Identifies CCR5-Mediated Glia-to-Glia Signaling as a Key Regulator of Brain Metastatic Progression.
    Cancer Res. 2025 Sep 16. doi: 10.1158/0008-5472.CAN-25-0237.
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    August 2025
  17. PAI B, Ramos SI, Cheng WS, Joshi T, et al
    Spatial Multi-omics Defines a Shared Tumor Infiltrative Signature at the Resection Margin in High-Grade Gliomas.
    Cancer Res. 2025 Aug 4. doi: 10.1158/0008-5472.CAN-24-4708.
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    July 2025
  18. LIU G, Zhang H, Chen S, Gao J, et al
    Mitochondrial Calcium Uniporter Links Acetyl-CoA Metabolism and H3K27 Acetylation to Maintain Glioblastoma Stem Cells.
    Cancer Res. 2025 Jul 25. doi: 10.1158/0008-5472.CAN-25-0419.
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  19. RICHMAN CM, Rasnitsyn A, Holgado BL, Vladoiu M, et al
    Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiation Therapy.
    Cancer Res. 2025 Jul 25. doi: 10.1158/0008-5472.CAN-24-3894.
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    June 2025
  20. KHAN KA, Qureshi AA, Xu P, Kuo HY, et al
    Immunological Tolerance to Luciferase and Fluorescent Proteins Using Tol Mice Enables Development of Improved Tumor Models for Investigating Immunity and Metastasis.
    Cancer Res. 2025;85:2165-2178.
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    May 2025
  21. BALAKRISHNAN I, Madhavan K, Pierce A, Michlin J, et al
    Development of an Anti-CD99 Antibody Enables Targeting of Diffuse Midline Glioma.
    Cancer Res. 2025 May 27. doi: 10.1158/0008-5472.CAN-24-5027.
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    April 2025
  22. SANG Y, Li Y, Song L, Alvarez AA, et al
    Editor's Note: TRIM59 Promotes Gliomagenesis by Inhibiting TC45 Dephosphorylation of STAT3.
    Cancer Res. 2025;85:1342.
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    March 2025
  23. KONG Y, Wang F, Jing R, Zhao Q, et al
    Targeting the SP/KLF Transcriptional Regulatory Network Synergizes with HDAC Inhibition to Impede Progression of H3K27M Diffuse Intrinsic Pontine Glioma.
    Cancer Res. 2025 Mar 7. doi: 10.1158/0008-5472.CAN-24-2227.
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    February 2025
  24. NOWICKA Z, Rentzeperis F, Tagal V, Teer JK, et al
    Interactions Between Ploidy and Resource Availability Shape Clonal Evolution in Glioblastoma.
    Cancer Res. 2025 Feb 11. doi: 10.1158/0008-5472.CAN-24-0401.
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  25. IPPOLITOV D, Lin YH, Spence J, Glogowska A, et al
    The Brain-Penetrant Pan ErbB Inhibitor Poziotinib Effectively Targets HER2+ Breast Cancer Brain Metastases.
    Cancer Res. 2025 Feb 11. doi: 10.1158/0008-5472.CAN-24-1793.
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    January 2025
  26. LIU T, Sun T, Chen X, Wu J, et al
    Targeting ARPC1B Overcomes Immune Checkpoint Inhibitor Resistance in Glioblastoma by Reversing Pro-tumorigenic Macrophage Polarization.
    Cancer Res. 2025 Jan 22. doi: 10.1158/0008-5472.CAN-24-2286.
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  27. ORR BA
    Transcription Factor Fingerprint Provides Clues for Brain Tumor Cell of Origin.
    Cancer Res. 2025;85:195-196.
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  28. JESSA S, De Cola A, Chandarana B, McNicholas M, et al
    FOXR2 Targets LHX6+/DLX+ Neural Lineages to Drive Central Nervous System Neuroblastoma.
    Cancer Res. 2025;85:231-250.
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  29. NINOMIYA T, Kemmotsu N, Mukohara F, Magari M, et al
    Myeloid Cells Induce Infiltration and Activation of B Cells and CD4+ T Follicular Helper Cells to Sensitize Brain Metastases to Combination Immunotherapy.
    Cancer Res. 2025 Jan 13. doi: 10.1158/0008-5472.CAN-24-2274.
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    December 2024
  30. DRUCKER KL, Jenkins RB, Schramek D
    Switching Drivers: Epigenetic Rewiring to Genetic Progression in Glioma.
    Cancer Res. 2024 Dec 30. doi: 10.1158/0008-5472.CAN-24-4907.
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  31. WU CY, Chen Y, Lin YJ, Wei KC, et al
    Tumor-Associated Microglia Secrete Extracellular ATP to Support Glioblastoma Progression.
    Cancer Res. 2024;84:4017-4030.
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    November 2024
  32. ZHOU Z, Yin X, Sun H, Lu J, et al
    PTBP1 Lactylation Promotes Glioma Stem Cell Maintenance through PFKFB4-Driven Glycolysis.
    Cancer Res. 2024 Nov 21. doi: 10.1158/0008-5472.CAN-24-1412.
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  33. IZAR B, Kim M
    Peritumoral Venous Vessels: Autobahn and Portal for T cells to Melanoma Brain Metastasis.
    Cancer Res. 2024 Nov 8. doi: 10.1158/0008-5472.CAN-24-4054.
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  34. CHEN X, Geng Y, Wei G, He D, et al
    Neural Circuitries between the Brain and Peripheral Solid Tumors.
    Cancer Res. 2024;84:3509-3521.
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    October 2024
  35. CHEN D, Le SB, Manektalia H, Liu T, et al
    The EP3-ZNF488 Axis Promotes Self-Renewal of Glioma Stem-like Cells to Induce Resistance to Tumor Treating Fields.
    Cancer Res. 2024 Oct 16. doi: 10.1158/0008-5472.CAN-23-3643.
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  36. RIMKUS TK, Carpenter RL, Sirkisoon S, Zhu D, et al
    Editor's Note: Truncated Glioma-Associated Oncogene Homolog 1 (tGLI1) Mediates Mesenchymal Glioblastoma via Transcriptional Activation of CD44.
    Cancer Res. 2024;84:3310.
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    September 2024
  37. PANG L, Zhou F, Chen P
    Lipid-laden macrophages recycle myelin to feed glioblastoma.
    Cancer Res. 2024 Sep 18. doi: 10.1158/0008-5472.CAN-24-3362.
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    August 2024
  38. LEE C, Yu D, Kim HS, Kim KS, et al
    Galectin-9 Mediates the Functions of Microglia in the Hypoxic Brain Tumor Microenvironment.
    Cancer Res. 2024 Aug 29. doi: 10.1158/0008-5472.CAN-23-3878.
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  39. MACLEOD G, Molaei F, Haider S, Almeida MP, et al
    Fitness Screens Map State-Specific Glioblastoma Stem Cell Vulnerabilities.
    Cancer Res. 2024 Aug 26. doi: 10.1158/0008-5472.CAN-23-4024.
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  40. JIAO M, Pirozzi CJ, Yu C, Bao X, et al
    Targeting Catechol-O-Methyltransferase Induces Mitochondrial Dysfunction and Enhances the Efficacy of Radiotherapy in Glioma.
    Cancer Res. 2024 Aug 1. doi: 10.1158/0008-5472.CAN-24-0134.
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    July 2024
  41. NAIR NU, Schaffer AA, Gertz EM, Cheng K, et al
    Chromosome 7 gain compensates for chromosome 10 loss in glioma.
    Cancer Res. 2024 Jul 30. doi: 10.1158/0008-5472.CAN-24-1366.
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    April 2024
  42. LOW JCM, Cao J, Hesse F, Wright AJ, et al
    Deuterium metabolic imaging differentiates glioblastoma metabolic subtypes and detects early response to chemoradiotherapy.
    Cancer Res. 2024 Apr 18. doi: 10.1158/0008-5472.CAN-23-2552.
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    March 2024
  43. HWANG GH, Pazyra-Murphy MF, Seo HS, Dhe-Paganon S, et al
    A Benzarone Derivative Inhibits EYA to Suppress Tumor Growth in SHH Medulloblastoma.
    Cancer Res. 2024;84:872-886.
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    February 2024
  44. LI J, Shih LK, Brat DJ
    Integrated Proteogenomics Uncover Mechanisms of Glioblastoma Evolution, Pointing to Novel Therapeutic Targets.
    Cancer Res. 2024 Feb 8. doi: 10.1158/0008-5472.CAN-24-0452.
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    January 2024
  45. UNDERHILL HR, Karsy M, Davidson CJ, Hellwig S, et al
    Subclonal Cancer Driver Mutations are Prevalent in the Unresected Peritumoral Edema of Adult Diffuse Gliomas.
    Cancer Res. 2024 Jan 25. doi: 10.1158/0008-5472.CAN-23-2557.
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  46. ZHAO D, Verhaak RGW
    Defining the role of extrachromosomal DNA amplifications in medulloblastoma.
    Cancer Res. 2024 Jan 4. doi: 10.1158/0008-5472.CAN-23-4025.
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    December 2023
  47. MALTA TM, Sabedot TS, Morosini NS, Datta I, et al
    The epigenetic evolution of glioma is determined by the IDH1 mutation status and treatment regimen.
    Cancer Res. 2023 Dec 20. doi: 10.1158/0008-5472.CAN-23-2093.
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  48. WANG D, Yan K, Yu H, Li H, et al
    Fimepinostat impairs NF-kappaB and PI3K/AKT signaling and enhances gemcitabine efficacy in H3K27M-mutated diffuse intrinsic pontine glioma.
    Cancer Res. 2023 Dec 14. doi: 10.1158/0008-5472.CAN-23-0394.
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    November 2023
  49. GUO X, Qiu W, Wang C, Qi Y, et al
    Neuronal activity promotes glioma progression by inducing proneural-to-mesenchymal transition in glioma stem cells.
    Cancer Res. 2023 Nov 14. doi: 10.1158/0008-5472.CAN-23-0609.
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    September 2023
  50. YIN J, Seo Y, Rhim J, Jin X, et al
    Crosstalk between PARN and EGFR-STAT3 Signaling Facilitates Self-Renewal and Proliferation of Glioblastoma Stem Cells.
    Cancer Res. 2023 Sep 25. doi: 10.1158/0008-5472.CAN-22-3965.
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    May 2023
  51. MONDAL I, Das O, Sun R, Gao J, et al
    PP2Ac Deficiency Enhances Tumor Immunogenicity by Activating STING-Type I Interferon Signaling in Glioblastoma.
    Cancer Res. 2023 May 23:CAN-22-3382. doi: 10.1158/0008-5472.CAN-22-3382.
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  52. JACKSON ER, Duchatel RJ, Staudt DE, Persson ML, et al
    ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma.
    Cancer Res. 2023 May 17:OF1-OF17. doi: 10.1158/0008-5472.CAN-23-0186.
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  53. BAYIK D, Bartels CF, Lovrenert K, Watson DC, et al
    Correction: Distinct Cell Adhesion Signature Defines Glioblastoma Myeloid-Derived Suppressor Cell Subsets.
    Cancer Res. 2023;83:1757.
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  54. JACKSON ER, Duchatel RJ, Staudt DE, Persson ML, et al
    ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma.
    Cancer Res. 2023 May 5:CAN-23-0186. doi: 10.1158/0008-5472.CAN-23-0186.
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    April 2023
  55. GUETTA-TERRIER C, Karambizi D, Akosman B, Zepecki JP, et al
    Chi3l1 is a modulator of glioma stem cell states and a therapeutic target in glioblastoma.
    Cancer Res. 2023 Apr 27:CAN-21-3629. doi: 10.1158/0008-5472.CAN-21-3629.
    >> Share

  56. MIRZAEI R, D'Mello C, Liu M, Nikolic A, et al
    Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor-Initiating Cells.
    Cancer Res. 2023 Apr 17:OF1-OF17. doi: 10.1158/0008-5472.CAN-22-3004.
    >> Share

  57. KARREMAN MA, Bauer AT, Solecki G, Berghoff AS, et al
    Active Remodeling of Capillary Endothelium via Cancer Cell-Derived MMP9 Promotes Metastatic Brain Colonization.
    Cancer Res. 2023;83:1299-1314.
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    March 2023
  58. ZAMLER DB, Hu J
    Primitive Oligodendrocyte Precursor Cells Are Highly Susceptible to Gliomagenic Transformation.
    Cancer Res. 2023;83:807-808.
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  59. PINE AR, Cirigliano SM, Singhania R, Nicholson J, et al
    Microenvironment-driven dynamic chromatin changes in glioblastoma recapitulate early neural development at single-cell resolution.
    Cancer Res. 2023 Mar 6:CAN-22-2872. doi: 10.1158/0008-5472.CAN-22-2872.
    >> Share


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