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Chronic Heart Failure

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Articles published in
J Mol Cell Cardiol
    October 2026
  1. IQBAL Z, Fiegle D, Minabari G, Heim C, et al
    A transmural t-tubule gradient in the human left ventricle is lost in heart failure: implications for myocardial biopsy assessment.
    J Mol Cell Cardiol. 2026 Oct 9:S0022-2828(26)00158.
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    September 2026
  2. KASSAB S, Albalawi Z, Khojah AM, Stonall CD, et al
    Loss of Miro1 drives cardiac and mitochondrial dysfunction exacerbated by metabolic stress.
    J Mol Cell Cardiol. 2026;218:157-173.
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  3. KOBAK KA, Zarzycka W, King CJ, Peelor FF 3rd, et al
    Cardiometabolic stress induces HFpEF with impaired bioenergetics and disrupted proteostasis in aged female mice.
    J Mol Cell Cardiol. 2026;218:151-156.
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    August 2026
  4. ZHAO W, Li Q, Chen H, Jiang R, et al
    The Deubiquitinase OTUD5 regulates cardiac hypertrophy by stabilizing TNF receptor associated factor 2.
    J Mol Cell Cardiol. 2026;217:163-175.
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    July 2026
  5. KAGAMI K, Nagatomo Y, Toya T, Yumita Y, et al
    Cell-specific ERK2 signaling in vascular smooth muscle cells drives vascular dysfunction and systolic heart failure.
    J Mol Cell Cardiol. 2026 Jul 28:S0022-2828(26)00118.
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  6. LEE A, Oh JG, Mitsuyama S, Wang H, et al
    A metabolically stable second-generation SERCA2a SUMOylation enhancer improves cardiac function in heart failure.
    J Mol Cell Cardiol. 2026;218:55-66.
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  7. HAMILTON S, Terentyeva R, Veress R, Perger F, et al
    Restoration of mitochondrial Ca(2+) and redox homeostasis by enhancement of SK channels rescues Ca(2+) cycling in HFpEF cardiomyocytes.
    J Mol Cell Cardiol. 2026;216:1-12.
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    June 2026
  8. TADOKORO T, Liu N, Olson EN
    Precision modification of heart failure signaling by CRISPR-Cas9 base editing.
    J Mol Cell Cardiol. 2026 Jun 19:S0022-2828(26)00092.
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    May 2026
  9. ZHOU H, Christopher CJ, Jones K, Pla MM, et al
    Myocardial metabolic remodeling in human end-stage ischemic and non-ischemic cardiomyopathy.
    J Mol Cell Cardiol. 2026;214:17-27.
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    April 2026
  10. YANG X, Kawasaki NK, Min J, Matsui T, et al
    Corrigendum to "Ferroptosis in heart failure" [Journal of Molecular and Cellular Cardiology, Volume 173 (2022) Pages 141-153].
    J Mol Cell Cardiol. 2026;215:51.
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  11. PITOULIS F, Pamias-Lopez B, Bedi K, Cheng L, et al
    Junctophilin-2 abundance is unaltered in human heart failure samples with disrupted T-tubules and contractility.
    J Mol Cell Cardiol. 2026;215:1-5.
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    January 2026
  12. LI M, Wang Y, Widdop RE
    Novel angiotensin receptor target as therapy for the diabetic heart: the AT(2)R.
    J Mol Cell Cardiol. 2026;210:83-97.
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    November 2025
  13. MILLER JA, Moise N, Mendez MJ, Weinberg SH, et al
    Interplay between variability in intrinsic cellular properties and heart failure-associated remodeling in a simulated population with human heart failure.
    J Mol Cell Cardiol. 2025 Nov 18:S0022-2828(25)00212.
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  14. ZHANG M, Chen C, Liu X, Zhou Z, et al
    Soluble epoxide hydrolase deficiency rescues heart failure with preserved ejection fraction by targeting cytochrome P450 2E1.
    J Mol Cell Cardiol. 2025;210:98-108.
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    October 2025
  15. SHUMLIAKIVSKA M, Fischer A, Muhly-Reinholz M, Leonard VE, et al
    The long non-coding RNA Snhg15 protects the heart after myocardial infarction.
    J Mol Cell Cardiol. 2025 Oct 27:S0022-2828(25)00195.
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  16. PAULS P, Fabritz L, Herting JR, Johann A, et al
    Catecholaminergic stress results in signs of heart failure in PP2A-PR72 overexpressor mice.
    J Mol Cell Cardiol. 2025;209:66-79.
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    September 2025
  17. CHEN D, Sindone A, Huang MLH, Peter K, et al
    Diabetic cardiomyopathy: insights into pathophysiology, diagnosis and clinical management.
    J Mol Cell Cardiol. 2025;206:55-69.
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    April 2025
  18. SPAGNOL G, Trease A, Zheng L, Sobota S, et al
    Cx45 regulation by kinases and impact of expression in heart failure.
    J Mol Cell Cardiol. 2025;203:91-105.
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  19. MCLENDON JM, Zhang X, Stein CS, Baehr LM, et al
    Gain and loss of the centrosomal protein taxilin-beta influences cardiac proteostasis and stress.
    J Mol Cell Cardiol. 2025;201:56-69.
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  20. SMOLGOVSKY S, Bayer AL, Aronovitz M, Vanni KMM, et al
    Experimental pressure overload induces a cardiac neoantigen specific humoral immune response.
    J Mol Cell Cardiol. 2025;201:87-93.
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    March 2025
  21. ROBERTS TD, Hutchinson DS, Wootten D, De Blasio MJ, et al
    Advances in incretin therapies for targeting cardiovascular disease in diabetes.
    J Mol Cell Cardiol. 2025;202:102-115.
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  22. CHEN Z, Zhong M, Lin Y, Zhang W, et al
    METTL7B-induced histone lactylation prevents heart failure by ameliorating cardiac remodelling.
    J Mol Cell Cardiol. 2025 Mar 9:S0022-2828(25)00046.
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    February 2025
  23. GUAN J, Fefelova N, Zhai P, Ikeda Y, et al
    Dual inhibition of Mst1 and Mst2 exacerbates cardiac dysfunction during pressure overload stress in mice.
    J Mol Cell Cardiol. 2025;199:133-136.
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    January 2025
  24. SHABANI P, Dong F, Yun J, Shin SY, et al
    Does coronary microvascular dysfunction play a role in heart failure with reduced ejection fraction?
    J Mol Cell Cardiol. 2025 Jan 28:S0022-2828(25)00007.
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    December 2024
  25. KASS DA
    Assessing and interpreting diastolic function in animal models of heart disease.
    J Mol Cell Cardiol. 2024;197:1-4.
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    November 2024
  26. KATTIH B, Fischer A, Muhly-Reinholz M, Tombor L, et al
    Inhibition of miR-92a normalizes vascular gene expression and prevents diastolic dysfunction in heart failure with preserved ejection fraction.
    J Mol Cell Cardiol. 2024 Nov 24:S0022-2828(24)00194.
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  27. FU J, Li L, Chen L, Su C, et al
    Corrigendum to "PGE2 protects against heart failure through inhibiting TGF-beta1 synthesis in cardiomyocytes and crosstalk between TGF-beta1 and GRK2" [Journal of Molecular and Cellular Cardiology. 172(2022) 63-77].
    J Mol Cell Cardiol. 2024 Nov 22:S0022-2828(24)00191.
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  28. ABBAS N, Bentele M, Waleczek FJG, Fuchs M, et al
    Ex vivo modelling of cardiac injury identifies ferroptosis-related pathways as a potential therapeutic avenue for translational medicine.
    J Mol Cell Cardiol. 2024;196:125-140.
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  29. ZERVOU S, McAndrew DJ, Lake HA, Kuznecova E, et al
    Cardiac function and energetics in mice with combined genetic augmentation of creatine and creatine kinase activity.
    J Mol Cell Cardiol. 2024;196:105-114.
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    October 2024
  30. JANI VP, Koleini N, Fenwick AJ, Sharp TE, et al
    Cardiomyocyte myofilament function in common animal models of heart failure with preserved ejection fraction.
    J Mol Cell Cardiol. 2024 Oct 18:S0022-2828(24)00166.
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  31. BEITO M, Taegtmeyer H
    Metabolic cycles: A unifying concept for energy transfer in the heart.
    J Mol Cell Cardiol. 2024;195:103-109.
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  32. FAN D, Wu R
    Mechanisms of the septic heart: From inflammatory response to myocardial edema.
    J Mol Cell Cardiol. 2024;195:73-82.
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  33. KAPLAN AD, Boyman L, Ward CW, Lederer WJ, et al
    Ryanodine receptor stabilization therapy suppresses Ca(2+)- based arrhythmias in a novel model of metabolic HFpEF.
    J Mol Cell Cardiol. 2024;195:68-72.
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    August 2024
  34. WALKER MA, Tian R
    NAD metabolism and heart failure: Mechanisms and therapeutic potentials.
    J Mol Cell Cardiol. 2024;195:45-54.
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    July 2024
  35. CANTRELL AC, Besanson J, Williams Q, Hoang N, et al
    Ferrostatin-1 specifically targets mitochondrial iron-sulfur clusters and aconitase to improve cardiac function in Sirtuin 3 cardiomyocyte knockout mice.
    J Mol Cell Cardiol. 2024;192:36-47.
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  36. LAHIRI SK, Lu J, Aguilar-Sanchez Y, Li H, et al
    Targeting Calpain-2-mediated Junctophilin-2 cleavage delays heart failure progression following myocardial infarction.
    J Mol Cell Cardiol. 2024 Jul 1:S0022-2828(24)00108.
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    April 2024
  37. CHOKSEY A, Carter RD, Thackray BD, Ball V, et al
    AICAR confers prophylactic cardioprotection in doxorubicin-induced heart failure in rats.
    J Mol Cell Cardiol. 2024;191:12-22.
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    March 2024
  38. NGUYEN T, Rosa-Garrido M, Sadek H, Garry DJ, et al
    Promoting cardiomyocyte proliferation for myocardial regeneration in large mammals.
    J Mol Cell Cardiol. 2024;188:52-60.
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    February 2024
  39. ANTIPENKO S, Mayfield N, Jinno M, Gunzer M, et al
    Neutrophils are indispensable for adverse cardiac remodeling in heart failure.
    J Mol Cell Cardiol. 2024;189:1-11.
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  40. SOMA Y, Tani H, Morita-Umei Y, Kishino Y, et al
    Pluripotent stem cell-based cardiac regenerative therapy for heart failure.
    J Mol Cell Cardiol. 2024;187:90-100.
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  41. SAKAMOTO T, Kelly DP
    Cardiac maturation.
    J Mol Cell Cardiol. 2024;187:38-50.
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    January 2024
  42. SHI L, Li X, Zhang M, Qin C, et al
    Downregulation of Wtap causes dilated cardiomyopathy and heart failure.
    J Mol Cell Cardiol. 2024 Jan 13:S0022-2828(24)00002.
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  43. SHINTANI Y, Fukushima S, Varela-Carver A, Lee J, et al
    Corrigendum to "Donor cell-type specific paracrine effects of cell transplantation for post-infarction heart failure" [J Mol Cell Cardiol 47 (2009) 288-295].
    J Mol Cell Cardiol. 2024 Jan 10:S0022-2828(24)00001.
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  44. CHU Y, Hua Y, He L, He J, et al
    beta-hydroxybutyrate administered at reperfusion reduces infarct size and preserves cardiac function by improving mitochondrial function through autophagy in male mice.
    J Mol Cell Cardiol. 2024;186:31-44.
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    November 2023
  45. MANGIONE MC, Wen J, Cao DJ
    Mechanistic target of rapamycin in regulating macrophage function in inflammatory cardiovascular diseases.
    J Mol Cell Cardiol. 2023;186:111-124.
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  46. CHEN S, Wang K, Wang J, Chen X, et al
    Profiling cardiomyocytes at single cell resolution reveals COX7B could be a potential target for attenuating heart failure in cardiac hypertrophy.
    J Mol Cell Cardiol. 2023;186:45-56.
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    October 2023
  47. WADDELL HMM, Mereacre V, Alvarado FJ, Munro ML, et al
    Clustering properties of the cardiac ryanodine receptor in health and heart failure.
    J Mol Cell Cardiol. 2023;185:38-49.
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  48. ZHAO C, Jiang X, Peng L, Zhang Y, et al
    Glimepiride, a novel soluble epoxide hydrolase inhibitor, protects against heart failure via increasing epoxyeicosatrienoic acids.
    J Mol Cell Cardiol. 2023;185:13-25.
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  49. MENASCHE P
    Human PSC-derived cardiac cells and their products: therapies for cardiac repair.
    J Mol Cell Cardiol. 2023;183:14-21.
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  50. PALIOURA D, Mellidis K, Ioannidou-Kabouri K, Galatou E, et al
    PPARdelta activation improves cardiac mitochondrial homeostasis in desmin deficient mice but does not alleviate systolic dysfunction.
    J Mol Cell Cardiol. 2023;183:27-41.
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    September 2023
  51. LIU Z, Liu Z, Xu X, Zhou Y, et al
    Role of ventrolateral part of ventromedial hypothalamus in post-myocardial infarction cardiac dysfunction induced by sympathetic nervous system.
    J Mol Cell Cardiol. 2023 Sep 30:S0022-2828(23)00154.
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  52. PEZHOUMAN A, Nguyen NB, Kay M, Kanjilal B, et al
    Cardiac regeneration - Past advancements, current challenges, and future directions.
    J Mol Cell Cardiol. 2023;182:75-85.
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    August 2023
  53. KMIETCZYK V, Oelschlager J, Gupta P, Varma E, et al
    Ythdf2 regulates cardiac remodeling through its mRNA target transcripts.
    J Mol Cell Cardiol. 2023;181:57-66.
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    July 2023
  54. KOBAYASHI S, Yamamoto T, Yano M
    RyR2-stabilization therapy with dantrolene against left ventricular remodeling and lethal arrhythmia in heart failure.
    J Mol Cell Cardiol. 2023 Jul 5:S0022-2828(23)00108.
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    June 2023
  55. MONTANES-AGUDO P, Pinto YM, Creemers EE
    Splicing factors in the heart: Uncovering shared and unique targets.
    J Mol Cell Cardiol. 2023;179:72-79.
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    May 2023
  56. YAMADA Y, Sadahiro T, Ieda M
    Development of direct cardiac reprogramming for clinical applications.
    J Mol Cell Cardiol. 2023;178:1-8.
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    April 2023
  57. MEHDIPOUR M, Park S, Huang GN
    Unlocking cardiomyocyte renewal potential for myocardial regeneration therapy.
    J Mol Cell Cardiol. 2023;177:9-20.
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  58. LI R, Xiang C, Li Y, Nie Y, et al
    Targeting immunoregulation for cardiac regeneration.
    J Mol Cell Cardiol. 2023;177:1-8.
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    March 2023
  59. GARRY GA, Olson EN
    Reprogramming of cardiac cell fate as a therapeutic strategy for ischemic heart disease.
    J Mol Cell Cardiol. 2023 Mar 28:S0022-2828(23)00058.
    >> Share

  60. FUJII S, Kobayashi S, Chang Y, Nawata J, et al
    RyR2-targeting therapy prevents left ventricular remodeling and ventricular tachycardia in post-infarction heart failure.
    J Mol Cell Cardiol. 2023 Mar 22:S0022-2828(23)00052.
    >> Share


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