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Autoimmune Disorders

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Articles published in
J Immunol
    October 2022
  1. SONG J, Anderson W, Hu A, Obata-Ninomiya K, et al
    CBLB Deficiency in Human CD4(+) T Cells Results in Resistance to T Regulatory Suppression through Multiple Mechanisms.
    J Immunol. 2022;209:1260-1271.
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    September 2022
  2. PARHAM KA, Tan XXS, Morelli DM, Chowdhury L, et al
    Pre-Germinal Center Interactions with T Cells Are Natural Checkpoints to Limit Autoimmune B Cell Responses.
    J Immunol. 2022 Sep 19. pii: jimmunol.2200534. doi: 10.4049/jimmunol.2200534.
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  3. ZHANG Q, Liu Y, Liao J, Wu R, et al
    Deficiency of p53 Causes the Inadequate Expression of miR-1246 in B Cells of Systemic Lupus Erythematosus.
    J Immunol. 2022 Sep 9. pii: jimmunol.2200307. doi: 10.4049/jimmunol.2200307.
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  4. GAO M, Liu S, Chatham WW, Mountz JD, et al
    IL-4-Induced Quiescence of Resting Naive B Cells Is Disrupted in Systemic Lupus Erythematosus.
    J Immunol. 2022 Sep 7. pii: jimmunol.2200409. doi: 10.4049/jimmunol.2200409.
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    August 2022
  5. WOODS J, Pemberton SE, Largent AD, Chiang K, et al
    Cutting Edge: Systemic Autoimmunity in Murine STAT3 Gain-of-Function Syndrome Is Characterized by Effector T Cell Expansion in the Absence of Overt Regulatory T Cell Dysfunction.
    J Immunol. 2022 Aug 22. pii: jimmunol.2100920. doi: 10.4049/jimmunol.2100920.
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  6. TAYLOR TC, Li Y, Li DD, Majumder S, et al
    Arid5a Mediates an IL-17-Dependent Pathway That Drives Autoimmunity but Not Antifungal Host Defense.
    J Immunol. 2022 Aug 8. pii: jimmunol.2200132. doi: 10.4049/jimmunol.2200132.
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  7. ZOU YR, Davidson A
    Nucleic Acid Sensing and Systemic Lupus Erythematosus: The Danger of Self.
    J Immunol. 2022;209:431-433.
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    July 2022
  8. CAO R, Li Z, Wu C, Ji S, et al
    Identification of a Small Molecule with Strong Anti-Inflammatory Activity in Experimental Autoimmune Encephalomyelitis and Sepsis through Blocking Gasdermin D Activation.
    J Immunol. 2022 Jul 29. pii: jimmunol.2100977. doi: 10.4049/jimmunol.2100977.
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    June 2022
  9. CHANG J, Bouchard A, Bouklouch Y, Panneton V, et al
    ICOS-Deficient Regulatory T Cells Can Prevent Spontaneous Autoimmunity but Are Impaired in Controlling Acute Inflammation.
    J Immunol. 2022 Jun 27. pii: jimmunol.2100897. doi: 10.4049/jimmunol.2100897.
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  10. DWYER JR, Racine JJ, Chapman HD, Quinlan A, et al
    Nfkbid Overexpression in Nonobese Diabetic Mice Elicits Complete Type 1 Diabetes Resistance in Part Associated with Enhanced Thymic Deletion of Pathogenic CD8 T Cells and Increased Numbers and Activity of Regulatory T Cells.
    J Immunol. 2022 Jun 27. pii: jimmunol.2100558. doi: 10.4049/jimmunol.2100558.
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  11. KIAPOUR N, Wu B, Wang Y, Seyedsadr M, et al
    Therapeutic Effect of Anti-CD52 Monoclonal Antibody in Multiple Sclerosis and Its Animal Models Is Mediated via T Regulatory Cells.
    J Immunol. 2022 Jun 24. pii: jimmunol.2100176. doi: 10.4049/jimmunol.2100176.
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  12. PODOJIL JR, Genardi S, Chiang MY, Kakade S, et al
    Tolerogenic Immune-Modifying Nanoparticles Encapsulating Multiple Recombinant Pancreatic beta Cell Proteins Prevent Onset and Progression of Type 1 Diabetes in Nonobese Diabetic Mice.
    J Immunol. 2022 Jun 20. pii: jimmunol.2200208. doi: 10.4049/jimmunol.2200208.
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  13. MEIER LA, Faragher JL, Osinski V, Auger JL, et al
    CD47 Promotes Autoimmune Valvular Carditis by Impairing Macrophage Efferocytosis and Enhancing Cytokine Production.
    J Immunol. 2022;208:2643-2651.
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  14. WONG KL, Li Z, Ma F, Wang D, et al
    SM03, an Anti-CD22 Antibody, Converts Cis-to-Trans Ligand Binding of CD22 against alpha2,6-Linked Sialic Acid Glycans and Immunomodulates Systemic Autoimmune Diseases.
    J Immunol. 2022 Jun 10. pii: jimmunol.2100820. doi: 10.4049/jimmunol.2100820.
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    May 2022
  15. AKAMA-GARREN EH, Carroll MC
    Lupus Susceptibility Loci Predispose Mice to Clonal Lymphocytic Responses and Myeloid Expansion.
    J Immunol. 2022;208:2403-2424.
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    April 2022
  16. KUMAR P, Balakrishnan S, Surendra Lele S, Setty S, et al
    Restoration of Follicular T-Regulatory/Helper Cell Balance by OX40L-JAG1 Cotreatment Suppresses Lupus Nephritis in NZBWF1/j Mice.
    J Immunol. 2022 Apr 25. pii: jimmunol.2200057. doi: 10.4049/jimmunol.2200057.
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    March 2022
  17. BEN NASR M, Robbins D, Parone P, Usuelli V, et al
    Pharmacologically Enhanced Regulatory Hematopoietic Stem Cells Revert Experimental Autoimmune Diabetes and Mitigate Other Autoimmune Disorders.
    J Immunol. 2022 Mar 23. pii: jimmunol.2100949. doi: 10.4049/jimmunol.2100949.
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  18. RICKASSEL C, Gnirck AC, Shaikh N, Adamiak V, et al
    Conventional NK Cells and Type 1 Innate Lymphoid Cells Do Not Influence Pathogenesis of Experimental Glomerulonephritis.
    J Immunol. 2022 Mar 16. pii: jimmunol.2101012. doi: 10.4049/jimmunol.2101012.
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  19. YUZEFPOLSKIY Y, Morawski P, Fahning M, Speake C, et al
    Cutting Edge: Effect of Disease-Modifying Therapies on SARS-CoV-2 Vaccine-Induced Immune Responses in Multiple Sclerosis Patients.
    J Immunol. 2022 Mar 14. pii: jimmunol.2101142. doi: 10.4049/jimmunol.2101142.
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  20. LV J, Han M, Xiang Z, Gong R, et al
    Chlorzoxazone Alleviates Experimental Autoimmune Encephalomyelitis via Inhibiting IL-6 Secretion of Dendritic Cells.
    J Immunol. 2022 Mar 11. pii: jimmunol.2100169. doi: 10.4049/jimmunol.2100169.
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  21. CHYUAN IT, Chu CL, Hsu CL, Pan MH, et al
    T Cell-Specific Deletion of TRAIL Receptor Reveals Its Critical Role for Regulating Pathologic T Cell Activation and Disease Induction in Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2022 Mar 9. pii: jimmunol.2100788. doi: 10.4049/jimmunol.2100788.
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  22. KAWANO S, Mitoma H, Inokuchi S, Yamauchi Y, et al
    TNFR2 Signaling Enhances Suppressive Abilities of Human Circulating T Follicular Regulatory Cells.
    J Immunol. 2022;208:1057-1065.
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  23. SUN D, Chan N, Shao H, Born WK, et al
    gammadelta T Cells Activated in Different Inflammatory Environments Are Functionally Distinct.
    J Immunol. 2022;208:1224-1231.
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    February 2022
  24. MANIVASAGAM S, Williams JL, Vollmer LL, Bollman B, et al
    Targeting IFN-lambda Signaling Promotes Recovery from Central Nervous System Autoimmunity.
    J Immunol. 2022 Feb 18. pii: jimmunol.2101041. doi: 10.4049/jimmunol.2101041.
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  25. KIM S, Boehme L, Nel L, Casian A, et al
    Defective STAT5 Activation and Aberrant Expression of BCL6 in Naive CD4 T Cells Enhances Follicular Th Cell-like Differentiation in Patients with Granulomatosis with Polyangiitis.
    J Immunol. 2022;208:807-818.
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  26. JIANG R, Qin Y, Wang Y, Xu X, et al
    Dynamic Number and Function of IL-10-Producing Regulatory B Cells in the Immune Microenvironment at Distinct Stages of Type 1 Diabetes.
    J Immunol. 2022 Feb 9. pii: jimmunol.2100357. doi: 10.4049/jimmunol.2100357.
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  27. NOMURA H, Wada N, Takahashi H, Kase Y, et al
    IgM to IgG Class Switching Is a Necessary Step for Pemphigus Phenotype Induction in Desmoglein 3-Specific B Cell Receptor Knock-in Mouse.
    J Immunol. 2022;208:582-593.
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    January 2022
  28. JORGE AM, Lao T, Kim R, Licciardi S, et al
    SCARF1-Induced Efferocytosis Plays an Immunomodulatory Role in Humans, and Autoantibodies Targeting SCARF1 Are Produced in Patients with Systemic Lupus Erythematosus.
    J Immunol. 2022 Jan 26. pii: jimmunol.2100532. doi: 10.4049/jimmunol.2100532.
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  29. LOMBARD-VADNAIS F, Collin R, Daudelin JF, Chabot-Roy G, et al
    The Idd2 Locus Confers Prominent Resistance to Autoimmune Diabetes.
    J Immunol. 2022 Jan 17. pii: jimmunol.2100456. doi: 10.4049/jimmunol.2100456.
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  30. JONES BE, Maerz MD, Bahnson HT, Somasundaram A, et al
    Fewer LAG-3(+) T Cells in Relapsing-Remitting Multiple Sclerosis and Type 1 Diabetes.
    J Immunol. 2022 Jan 12. pii: jimmunol.2100850. doi: 10.4049/jimmunol.2100850.
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    December 2021
  31. MERLO LMF, Peng W, DuHadaway JB, Montgomery JD, et al
    The Immunomodulatory Enzyme IDO2 Mediates Autoimmune Arthritis through a Nonenzymatic Mechanism.
    J Immunol. 2021 Dec 29. pii: jimmunol.2100705. doi: 10.4049/jimmunol.2100705.
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  32. RENNA V, Surova E, Khadour A, Datta M, et al
    Defective Allelic Exclusion by IgD in the Absence of Autoantigen.
    J Immunol. 2021 Dec 20. pii: jimmunol.2100726. doi: 10.4049/jimmunol.2100726.
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  33. MONTEITH AJ, Miller JM, Williams JM, Voss K, et al
    Altered Mitochondrial Homeostasis during Systemic Lupus Erythematosus Impairs Neutrophil Extracellular Trap Formation Rendering Neutrophils Ineffective at Combating Staphylococcus aureus.
    J Immunol. 2021 Dec 20. pii: jimmunol.2100752. doi: 10.4049/jimmunol.2100752.
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  34. INOUE M, Nakahama T, Yamasaki R, Shibuya T, et al
    An Aicardi-Goutieres Syndrome-Causative Point Mutation in Adar1 Gene Invokes Multiorgan Inflammation and Late-Onset Encephalopathy in Mice.
    J Immunol. 2021;207:3016-3027.
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  35. CZEH M, Stable S, Kramer S, Tepe L, et al
    DNMT1 Deficiency Impacts on Plasmacytoid Dendritic Cells in Homeostasis and Autoimmune Disease.
    J Immunol. 2021 Dec 13. pii: jimmunol.2100624. doi: 10.4049/jimmunol.2100624.
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    November 2021
  36. WHITTINGTON KB, Prislovsky A, Beaty J, Albritton L, et al
    CD8(+) T Cells Expressing an HLA-DR1 Chimeric Antigen Receptor Target Autoimmune CD4(+) T Cells in an Antigen-Specific Manner and Inhibit the Development of Autoimmune Arthritis.
    J Immunol. 2021 Nov 24. pii: jimmunol.2100643. doi: 10.4049/jimmunol.2100643.
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  37. O'CONNELL P, Blake MK, Godbehere S, Aldhamen YA, et al
    Absence of ERAP1 in B Cells Increases Susceptibility to Central Nervous System Autoimmunity, Alters B Cell Biology, and Mechanistically Explains Genetic Associations between ERAP1 and Multiple Sclerosis.
    J Immunol. 2021 Nov 22. pii: jimmunol.2100813. doi: 10.4049/jimmunol.2100813.
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  38. LEE J, Cullum E, Stoltz K, Bachmann N, et al
    Mouse Homologue of Human HLA-DO Does Not Preempt Autoimmunity but Controls Murine Gammaherpesvirus MHV68.
    J Immunol. 2021 Nov 22. pii: jimmunol.2100650. doi: 10.4049/jimmunol.2100650.
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  39. HU Y, Chen G, Huang J, Li Z, et al
    The Calcium Channel Inhibitor Nimodipine Shapes the Uveitogenic T Cells and Protects Mice from Experimental Autoimmune Uveitis through the p38-MAPK Signaling Pathway.
    J Immunol. 2021 Nov 19. pii: jimmunol.2100568. doi: 10.4049/jimmunol.2100568.
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  40. ALLENSPACH EJ, Shubin NJ, Cerosaletti K, Mikacenic C, et al
    The Autoimmune Risk R262W Variant of the Adaptor SH2B3 Improves Survival in Sepsis.
    J Immunol. 2021 Nov 5. pii: jimmunol.2100454. doi: 10.4049/jimmunol.2100454.
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  41. CHUNG H, Komada T, Lau A, Chappellaz M, et al
    AIM2 Suppresses Inflammation and Epithelial Cell Proliferation during Glomerulonephritis.
    J Immunol. 2021 Nov 5. pii: jimmunol.2100483. doi: 10.4049/jimmunol.2100483.
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  42. TSE BCY, Ireland RA, Lee JY, Marsh-Wakefield F, et al
    Exposure to Systemic Immunosuppressive Ultraviolet Radiation Alters T Cell Recirculation through Sphingosine-1-Phosphate.
    J Immunol. 2021;207:2278-2287.
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    October 2021
  43. BARNAS JL, Albrecht J, Meednu N, Alzamareh DF, et al
    B Cell Activation and Plasma Cell Differentiation Are Promoted by IFN-lambda in Systemic Lupus Erythematosus.
    J Immunol. 2021 Oct 27. pii: jimmunol.2100339. doi: 10.4049/jimmunol.2100339.
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  44. WELIWITIGODA A, Palle P, Gessner M, Hubbard NW, et al
    Cutting Edge: DOCK8 Regulates a Subset of Dendritic Cells That Is Critical for the Development of Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2021 Oct 18. pii: jimmunol.2001294. doi: 10.4049/jimmunol.2001294.
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  45. LI M, Itoh A, Xi J, Yu C, et al
    Enhancing Antigen Presentation and Inducing Antigen-Specific Immune Tolerance with Amphiphilic Peptides.
    J Immunol. 2021;207:2051-2059.
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    September 2021
  46. CHIANG K, Largent AD, Arkatkar T, Thouvenel CD, et al
    Cutting Edge: A Threshold of B Cell Costimulatory Signals Is Required for Spontaneous Germinal Center Formation in Autoimmunity.
    J Immunol. 2021 Sep 29. pii: jimmunol.2100548. doi: 10.4049/jimmunol.2100548.
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  47. ARAKAWA A, Reeves E, Vollmer S, Arakawa Y, et al
    ERAP1 Controls the Autoimmune Response against Melanocytes in Psoriasis by Generating the Melanocyte Autoantigen and Regulating Its Amount for HLA-C*06:02 Presentation.
    J Immunol. 2021 Sep 27. pii: jimmunol.2100686. doi: 10.4049/jimmunol.2100686.
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  48. MANDEL-BREHM C, Fichtner ML, Jiang R, Winton VJ, et al
    Elevated N-Linked Glycosylation of IgG V Regions in Myasthenia Gravis Disease Subtypes.
    J Immunol. 2021 Sep 20. pii: jimmunol.2100225. doi: 10.4049/jimmunol.2100225.
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  49. CIECKO AE, Schauder DM, Foda B, Petrova G, et al
    Self-Renewing Islet TCF1(+) CD8 T Cells Undergo IL-27-Controlled Differentiation to Become TCF1(-) Terminal Effectors during the Progression of Type 1 Diabetes.
    J Immunol. 2021 Sep 10. pii: jimmunol.2100362. doi: 10.4049/jimmunol.2100362.
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  50. ZHOU M, Dascani P, Ding C, Kos JT, et al
    Integrin CD11b Negatively Regulates B Cell Receptor Signaling to Shape Humoral Response during Immunization and Autoimmunity.
    J Immunol. 2021 Sep 1. pii: jimmunol.2100070. doi: 10.4049/jimmunol.2100070.
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    August 2021
  51. LEE DSW, Yam JY, Grasmuck C, Dasoveanu D, et al
    CCR6 Expression on B Cells Is Not Required for Clinical or Pathological Presentation of MOG Protein-Induced Experimental Autoimmune Encephalomyelitis despite an Altered Germinal Center Response.
    J Immunol. 2021 Aug 16. pii: jimmunol.2001413. doi: 10.4049/jimmunol.2001413.
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  52. BOULET S, Odagiu L, Dong M, Lebel ME, et al
    NR4A3 Mediates Thymic Negative Selection.
    J Immunol. 2021;207:1055-1064.
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  53. MANOHARAN I, Swafford D, Shanmugam A, Patel N, et al
    Activation of Transcription Factor 4 in Dendritic Cells Controls Th1/Th17 Responses and Autoimmune Neuroinflammation.
    J Immunol. 2021 Aug 4. pii: jimmunol.2100010. doi: 10.4049/jimmunol.2100010.
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  54. PERRY DJ, Peters LD, Lakshmi PS, Zhang L, et al
    Overexpression of the PTPN22 Autoimmune Risk Variant LYP-620W Fails to Restrain Human CD4(+) T Cell Activation.
    J Immunol. 2021;207:849-859.
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    July 2021
  55. GYAPON-QUAST F, Goicoechea de Jorge E, Malik T, Wu N, et al
    Defining the Glycosaminoglycan Interactions of Complement Factor H-Related Protein 5.
    J Immunol. 2021;207:534-541.
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  56. VAN ASTEN SD, Unger PP, Marsman C, Bliss S, et al
    Soluble FAS Ligand Enhances Suboptimal CD40L/IL-21-Mediated Human Memory B Cell Differentiation into Antibody-Secreting Cells.
    J Immunol. 2021;207:449-458.
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  57. Top Reads.
    J Immunol. 2021;207:1-2.
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    June 2021
  58. CHURCH ME, Ceja G, McGeehan M, Miller MC, et al
    Meningeal B Cell Clusters Correlate with Submeningeal Pathology in a Natural Model of Multiple Sclerosis.
    J Immunol. 2021 Jun 23. pii: jimmunol.2000514. doi: 10.4049/jimmunol.2000514.
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  59. NEEDHAM EJ, Stoevesandt O, Thelin EP, Zetterberg H, et al
    Complex Autoantibody Responses Occur following Moderate to Severe Traumatic Brain Injury.
    J Immunol. 2021 Jun 18. pii: jimmunol.2001309. doi: 10.4049/jimmunol.2001309.
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  60. ZHANG J, Bouch RJ, Blekhman MG, He Z, et al
    USP19 Suppresses Th17-Driven Pathogenesis in Autoimmunity.
    J Immunol. 2021 Jun 16. pii: jimmunol.2100205. doi: 10.4049/jimmunol.2100205.
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  61. KO MK, Shao H, Kaplan HJ, Sun D, et al
    Timing Effect of Adenosine-Directed Immunomodulation on Mouse Experimental Autoimmune Uveitis.
    J Immunol. 2021 Jun 14. pii: jimmunol.2100182. doi: 10.4049/jimmunol.2100182.
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  62. XIE JH, Zhang Y, Loubeau M, Mangan P, et al
    Mouse IL-2/CD25 Fusion Protein Induces Regulatory T Cell Expansion and Immune Suppression in Preclinical Models of Systemic Lupus Erythematosus.
    J Immunol. 2021 Jun 9. pii: jimmunol.2100078. doi: 10.4049/jimmunol.2100078.
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  63. SONODA S, Murata S, Kato H, Zakaria F, et al
    Targeting of Deciduous Tooth Pulp Stem Cell-Derived Extracellular Vesicles on Telomerase-Mediated Stem Cell Niche and Immune Regulation in Systemic Lupus Erythematosus.
    J Immunol. 2021 Jun 2. pii: jimmunol.2001312. doi: 10.4049/jimmunol.2001312.
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    May 2021
  64. SCHELL SL, Bricker KN, Fike AJ, Chodisetti SB, et al
    Context-Dependent miR-21 Regulation of TLR7-Mediated Autoimmune and Foreign Antigen-Driven Antibody-Forming Cell and Germinal Center Responses.
    J Immunol. 2021 May 26. pii: jimmunol.2001039. doi: 10.4049/jimmunol.2001039.
    >> Share

  65. CHALAN P, Thomas N, Caturegli P
    Th17 Cells Contribute to the Pathology of Autoimmune Hypophysitis.
    J Immunol. 2021 May 19. pii: jimmunol.2001073. doi: 10.4049/jimmunol.2001073.
    >> Share

  66. CAI H, Liu X, Zhang F, Han QY, et al
    G3BP1 Inhibition Alleviates Intracellular Nucleic Acid-Induced Autoimmune Responses.
    J Immunol. 2021;206:2453-2467.
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  67. HE R, Wu S, Gao R, Chen J, et al
    Identification of a Long Noncoding RNA TRAF3IP2-AS1 as Key Regulator of IL-17 Signaling through the SRSF10-IRF1-Act1 Axis in Autoimmune Diseases.
    J Immunol. 2021;206:2353-2365.
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  68. Top Reads.
    J Immunol. 2021;206:2249.
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  69. LI Q, Feng C, Li L, Xu G, et al
    Lipid Receptor G2A-Mediated Signal Pathway Plays a Critical Role in Inflammatory Response by Promoting Classical Macrophage Activation.
    J Immunol. 2021;206:2338-2352.
    >> Share

    April 2021
  70. INOUE M, Yamashita K, Tsuji Y, Miki M, et al
    Characterization of a TNFR2-Selective Agonistic TNF-alpha Mutant and Its Derivatives as an Optimal Regulatory T Cell Expander.
    J Immunol. 2021;206:1740-1751.
    >> Share

  71. PAN W, Nagpal K, Suarez-Fueyo A, Ferretti A, et al
    The Regulatory Subunit PPP2R2A of PP2A Enhances Th1 and Th17 Differentiation through Activation of the GEF-H1/RhoA/ROCK Signaling Pathway.
    J Immunol. 2021;206:1719-1728.
    >> Share

  72. MORIN F, Singh N, Mdzomba JB, Dumas A, et al
    Conditional Deletions of Hdc Confirm Roles of Histamine in Anaphylaxis and Circadian Activity but Not in Autoimmune Encephalomyelitis.
    J Immunol. 2021 Apr 12. pii: jimmunol.2000719. doi: 10.4049/jimmunol.2000719.
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  73. JOHNSON BM, Uchimura T, Gallovic MD, Thamilarasan M, et al
    STING Agonist Mitigates Experimental Autoimmune Encephalomyelitis by Stimulating Type I IFN-Dependent and -Independent Immune-Regulatory Pathways.
    J Immunol. 2021 Apr 5. pii: jimmunol.2001317. doi: 10.4049/jimmunol.2001317.
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  74. LANGRISH CL, Bradshaw JM, Francesco MR, Owens TD, et al
    Preclinical Efficacy and Anti-Inflammatory Mechanisms of Action of the Bruton Tyrosine Kinase Inhibitor Rilzabrutinib for Immune-Mediated Disease.
    J Immunol. 2021;206:1454-1468.
    >> Share

  75. LIN X, Tawch S, Wong HT, Roy S, et al
    Nrf2 through Aryl Hydrocarbon Receptor Regulates IL-22 Response in CD4(+) T Cells.
    J Immunol. 2021;206:1540-1548.
    >> Share

  76. CHIKUMA S, Yamanaka S, Nakagawa S, Ueda MT, et al
    TRIM28 Expression on Dendritic Cells Prevents Excessive T Cell Priming by Silencing Endogenous Retrovirus.
    J Immunol. 2021;206:1528-1539.
    >> Share

    March 2021
  77. CHO T, Sato H, Wakamatsu A, Ohashi R, et al
    Mood Disorder in Systemic Lupus Erythematosus Induced by Antiribosomal P Protein Antibodies Associated with Decreased Serum and Brain Tryptophan.
    J Immunol. 2021 Mar 31. pii: jimmunol.2000260. doi: 10.4049/jimmunol.2000260.
    >> Share

  78. BEN NASR M, Usuelli V, Seelam AJ, D'Addio F, et al
    Regulatory B Cells in Autoimmune Diabetes.
    J Immunol. 2021;206:1117-1125.
    >> Share

  79. BRATE AA, Boyden AW, Jensen IJ, Badovinac VP, et al
    A Functionally Distinct CXCR3(+)/IFN-gamma(+)/IL-10(+) Subset Defines Disease-Suppressive Myelin-Specific CD8 T Cells.
    J Immunol. 2021;206:1151-1160.
    >> Share

  80. NANDEDKAR-KULKARNI N, Esakov E, Gregg B, Atkinson MA, et al
    Insulin Receptor-Expressing T Cells Appear in Individuals at Risk for Type 1 Diabetes and Can Move into the Pancreas in C57BL/6 Transgenic Mice.
    J Immunol. 2021 Mar 3. pii: jimmunol.1900357. doi: 10.4049/jimmunol.1900357.
    >> Share

  81. CHEN L, Bai J, Peng D, Gao Y, et al
    SZB120 Exhibits Immunomodulatory Effects by Targeting eIF2alpha to Suppress Th17 Cell Differentiation.
    J Immunol. 2021;206:953-962.
    >> Share

  82. THOMSON AS, Mai SH, Bouma G, Herdman M, et al
    Structure and Functional Characterization of a Humanized Anti-CCL20 Antibody following Exposure to Serum Reveals the Formation of Immune Complex That Leads to Toxicity.
    J Immunol. 2021;206:1067-1076.
    >> Share

    February 2021
  83. SALINAS VH, Stuve O
    Systems Approaches to Unravel T Cell Function and Therapeutic Potential in Autoimmune Disease.
    J Immunol. 2021;206:669-675.
    >> Share

  84. CUNNINGHAM KT, Finlay CM, Mills KHG
    Helminth Imprinting of Hematopoietic Stem Cells Sustains Anti-Inflammatory Trained Innate Immunity That Attenuates Autoimmune Disease.
    J Immunol. 2021 Feb 12. pii: jimmunol.2001225. doi: 10.4049/jimmunol.2001225.
    >> Share

  85. ALLARD-CHAMARD H, Alsufyani F, Kaneko N, Xing K, et al
    CD4(+)CTLs in Fibrosing Mediastinitis Linked to Histoplasma capsulatum.
    J Immunol. 2021;206:524-530.
    >> Share

    January 2021
  86. HUARD A, Do HN, Frank AC, Sirait-Fischer E, et al
    IL-38 Ablation Reduces Local Inflammation and Disease Severity in Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2021 Jan 27. pii: jimmunol.2000923. doi: 10.4049/jimmunol.2000923.
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  87. BATES NA, Li A, Fan T, Cutcliffe MP, et al
    Gut Commensal Segmented Filamentous Bacteria Fine-Tune T Follicular Regulatory Cells to Modify the Severity of Systemic Autoimmune Arthritis.
    J Immunol. 2021 Jan 18. pii: jimmunol.2000663. doi: 10.4049/jimmunol.2000663.
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  88. SIM JH, Ambler WG, Sollohub IF, Howlader MJ, et al
    Immune Cell-Stromal Circuitry in Lupus Photosensitivity.
    J Immunol. 2021;206:302-309.
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  89. SUMIYOSHI M, Kotani Y, Ikuta Y, Suzue K, et al
    Arf1 and Arf6 Synergistically Maintain Survival of T Cells during Activation.
    J Immunol. 2021;206:366-375.
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  90. MOCKUS TE, Munie A, Atkinson JR, Segal BM, et al
    Encephalitogenic and Regulatory CD8 T Cells in Multiple Sclerosis and Its Animal Models.
    J Immunol. 2021;206:3-10.
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    December 2020
  91. XU Z, Lin CC, Ho S, Vlad G, et al
    Suppression of Experimental Autoimmune Encephalomyelitis by ILT3.Fc.
    J Immunol. 2020 Dec 23. pii: jimmunol.2000265. doi: 10.4049/jimmunol.2000265.
    >> Share

  92. TURNIER JL, Kahlenberg JM
    The Role of Cutaneous Type I IFNs in Autoimmune and Autoinflammatory Diseases.
    J Immunol. 2020;205:2941-2950.
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    November 2020
  93. BONAMI RH, Nyhoff LE, McNitt DH, Hulbert C, et al
    T-B Lymphocyte Interactions Promote Type 1 Diabetes Independently of SLAM-Associated Protein.
    J Immunol. 2020 Nov 16. pii: jimmunol.1900464. doi: 10.4049/jimmunol.1900464.
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  94. HAYES ET, Hagan CE, Khoryati L, Gavin MA, et al
    Regulatory T Cells Maintain Selective Access to IL-2 and Immune Homeostasis despite Substantially Reduced CD25 Function.
    J Immunol. 2020;205:2667-2678.
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  95. PINHEIRO DF, Szenes-Nagy AB, Maurano MM, Lietzenmayer M, et al
    Cutting Edge: Tissue Antigen Expression Levels Fine-Tune T Cell Differentiation Decisions In Vivo.
    J Immunol. 2020;205:2577-2582.
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  96. SUNGNAK W, Wagner A, Kowalczyk MS, Bod L, et al
    T Follicular Regulatory Cell-Derived Fibrinogen-like Protein 2 Regulates Production of Autoantibodies and Induction of Systemic Autoimmunity.
    J Immunol. 2020 Nov 9. pii: jimmunol.2000748. doi: 10.4049/jimmunol.2000748.
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  97. VAN DER POEL M, Hoepel W, Hamann J, Huitinga I, et al
    IgG Immune Complexes Break Immune Tolerance of Human Microglia.
    J Immunol. 2020;205:2511-2518.
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    October 2020
  98. RACINE JJ, Chapman HD, Doty R, Cairns BM, et al
    T Cells from NOD-PerIg Mice Target Both Pancreatic and Neuronal Tissue.
    J Immunol. 2020;205:2026-2038.
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  99. TOSSBERG JT, Heinrich RM, Farley VM, Crooke PS 3rd, et al
    Adenosine-to-Inosine RNA Editing of Alu Double-Stranded (ds)RNAs Is Markedly Decreased in Multiple Sclerosis and Unedited Alu dsRNAs Are Potent Activators of Proinflammatory Transcriptional Responses.
    J Immunol. 2020 Oct 12. pii: jimmunol.2000384. doi: 10.4049/jimmunol.2000384.
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    September 2020
  100. TAYLOR S, Whitfield M, Barratt J, Didangelos A, et al
    The Metalloproteinase ADAMTS5 Is Expressed by Interstitial Inflammatory Cells in IgA Nephropathy and Is Proteolytically Active on the Kidney Matrix.
    J Immunol. 2020 Sep 11. pii: jimmunol.2000448. doi: 10.4049/jimmunol.2000448.
    >> Share

  101. BARIK S, Cattin-Roy AN, Ukah TK, Miller MM, et al
    Type II Cytokines Fine-Tune Thymic T Cell Selection to Offset Murine Central Nervous System Autoimmunity.
    J Immunol. 2020 Sep 11. pii: jimmunol.2000614. doi: 10.4049/jimmunol.2000614.
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  102. FREUDENHAMMER M, Voll RE, Binder SC, Keller B, et al
    Naive- and Memory-like CD21(low) B Cell Subsets Share Core Phenotypic and Signaling Characteristics in Systemic Autoimmune Disorders.
    J Immunol. 2020 Sep 9. pii: jimmunol.2000343. doi: 10.4049/jimmunol.2000343.
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  103. DURIGUTTO P, Macor P, Pozzi N, Agostinis C, et al
    Complement Activation and Thrombin Generation by MBL Bound to beta2-Glycoprotein I.
    J Immunol. 2020;205:1385-1392.
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    August 2020
  104. LI M, Yang C, Wang Y, Song W, et al
    The Expression of P2X7 Receptor on Th1, Th17, and Regulatory T Cells in Patients with Systemic Lupus Erythematosus or Rheumatoid Arthritis and Its Correlations with Active Disease.
    J Immunol. 2020 Aug 31. pii: jimmunol.2000222. doi: 10.4049/jimmunol.2000222.
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  105. YE C, Low BE, Wiles MV, Brusko TM, et al
    CD70 Inversely Regulates Regulatory T Cells and Invariant NKT Cells and Modulates Type 1 Diabetes in NOD Mice.
    J Immunol. 2020 Aug 31. pii: jimmunol.2000148. doi: 10.4049/jimmunol.2000148.
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  106. ACHARYA M, Raso F, Sagadiev S, Gilbertson E, et al
    B Cell alphav Integrins Regulate TLR-Driven Autoimmunity.
    J Immunol. 2020 Aug 28. pii: jimmunol.1901056. doi: 10.4049/jimmunol.1901056.
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  107. FINLAY CM, Cunningham KT, Doyle B, Mills KHG, et al
    IL-33-Stimulated Murine Mast Cells Polarize Alternatively Activated Macrophages, Which Suppress T Cells That Mediate Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2020 Aug 28. pii: jimmunol.1901321. doi: 10.4049/jimmunol.1901321.
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  108. ZHANG X, Ciesielski M, Fenstermaker RA, Kaminski HJ, et al
    The Presence of Survivin on B Cells from Myasthenia Gravis Patients and the Potential of an Antibody to a Modified Survivin Peptide to Alleviate Weakness in an Animal Model.
    J Immunol. 2020 Aug 24. pii: jimmunol.2000482. doi: 10.4049/jimmunol.2000482.
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    July 2020
  109. TUCKER CG, Mitchell JS, Martinov T, Burbach BJ, et al
    Adoptive T Cell Therapy with IL-12-Preconditioned Low-Avidity T Cells Prevents Exhaustion and Results in Enhanced T Cell Activation, Enhanced Tumor Clearance, and Decreased Risk for Autoimmunity.
    J Immunol. 2020 Jul 31. pii: jimmunol.2000007. doi: 10.4049/jimmunol.2000007.
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  110. HONG H, Gao M, Wu Q, Yang P, et al
    IL-23 Promotes a Coordinated B Cell Germinal Center Program for Class-Switch Recombination to IgG2b in BXD2 Mice.
    J Immunol. 2020;205:346-358.
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  111. CLARKE J, Yaqubi M, Futhey NC, Sedaghat S, et al
    Vitamin D Regulates MerTK-Dependent Phagocytosis in Human Myeloid Cells.
    J Immunol. 2020;205:398-406.
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  112. RIJVERS L, Melief MJ, van Langelaar J, van der Vuurst de Vries RM, et al
    The Role of Autoimmunity-Related Gene CLEC16A in the B Cell Receptor-Mediated HLA Class II Pathway.
    J Immunol. 2020 Jul 8. pii: jimmunol.1901409. doi: 10.4049/jimmunol.1901409.
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  113. STARK AK, Davenport ECM, Patton DT, Scudamore CL, et al
    Loss of Phosphatidylinositol 3-Kinase Activity in Regulatory T Cells Leads to Neuronal Inflammation.
    J Immunol. 2020;205:78-89.
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    June 2020
  114. LI Z, He C, Zhang J, Zhang H, et al
    P2Y6 Deficiency Enhances Dendritic Cell-Mediated Th1/Th17 Differentiation and Aggravates Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2020 Jun 17. pii: jimmunol.1900916. doi: 10.4049/jimmunol.1900916.
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  115. VANARSA K, Henderson J, Soomro S, Qin L, et al
    Upregulation of Proinflammatory Bradykinin Peptides in Systemic Lupus Erythematosus and Rheumatoid Arthritis.
    J Immunol. 2020 Jun 15. pii: jimmunol.1801167. doi: 10.4049/jimmunol.1801167.
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  116. BOYDEN AW, Brate AA, Stephens LM, Karandikar NJ, et al
    Immune Autoregulatory CD8 T Cells Require IFN-gamma Responsiveness to Optimally Suppress Central Nervous System Autoimmunity.
    J Immunol. 2020 Jun 12. pii: jimmunol.2000211. doi: 10.4049/jimmunol.2000211.
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  117. WU CY, Hua KF, Hsu WH, Suzuki Y, et al
    IgA Nephropathy Benefits from Compound K Treatment by Inhibiting NF-kappaB/NLRP3 Inflammasome and Enhancing Autophagy and SIRT1.
    J Immunol. 2020 Jun 1. pii: jimmunol.1900284. doi: 10.4049/jimmunol.1900284.
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    May 2020
  118. QIU R, Yu X, Wang L, Han Z, et al
    Inhibition of Glycolysis in Pathogenic TH17 Cells through Targeting a miR -21-Peli1-c-Rel Pathway Prevents Autoimmunity.
    J Immunol. 2020 May 15. pii: jimmunol.2000060. doi: 10.4049/jimmunol.2000060.
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  119. BATRA L, Shrestha P, Zhao H, Woodward KB, et al
    Localized Immunomodulation with PD-L1 Results in Sustained Survival and Function of Allogeneic Islets without Chronic Immunosuppression.
    J Immunol. 2020;204:2840-2851.
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  120. SKOPELJA-GARDNER S, Colonna L, Hermanson P, Sun X, et al
    Complement Deficiencies Result in Surrogate Pathways of Complement Activation in Novel Polygenic Lupus-like Models of Kidney Injury.
    J Immunol. 2020;204:2627-2640.
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  121. EICHMANN M, Baptista R, Ellis RJ, Heck S, et al
    Costimulation Blockade Disrupts CD4(+) T Cell Memory Pathways and Uncouples Their Link to Decline in beta-Cell Function in Type 1 Diabetes.
    J Immunol. 2020 May 13. pii: jimmunol.1901439. doi: 10.4049/jimmunol.1901439.
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    April 2020
  122. THAPA M, Tedesco D, Gumber S, Elrod EJ, et al
    Blockade of BAFF Reshapes the Hepatic B Cell Receptor Repertoire and Attenuates Autoantibody Production in Cholestatic Liver Disease.
    J Immunol. 2020 Apr 24. pii: jimmunol.1900391. doi: 10.4049/jimmunol.1900391.
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  123. FODA BM, Ciecko AE, Serreze DV, Ridgway WM, et al
    The CD137 Ligand Is Important for Type 1 Diabetes Development but Dispensable for the Homeostasis of Disease-Suppressive CD137(+) FOXP3(+) Regulatory CD4 T Cells.
    J Immunol. 2020 Apr 15. pii: jimmunol.1900485. doi: 10.4049/jimmunol.1900485.
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  124. CHODISETTI SB, Fike AJ, Domeier PP, Schell SL, et al
    Serine Phosphorylation of the STAT1 Transactivation Domain Promotes Autoreactive B Cell and Systemic Autoimmunity Development.
    J Immunol. 2020 Apr 6. pii: jimmunol.2000170. doi: 10.4049/jimmunol.2000170.
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    March 2020
  125. IHANTOLA EL, Ilmonen H, Kailaanmaki A, Rytkonen-Nissinen M, et al
    Characterization of Proinsulin T Cell Epitopes Restricted by Type 1 Diabetes-Associated HLA Class II Molecules.
    J Immunol. 2020 Mar 30. pii: jimmunol.1901079. doi: 10.4049/jimmunol.1901079.
    >> Share

    February 2020
  126. FERNANDO R, Atkins SJ, Smith TJ
    Slit2 May Underlie Divergent Induction by Thyrotropin of IL-23 and IL-12 in Human Fibrocytes.
    J Immunol. 2020 Feb 21. pii: jimmunol.1900434. doi: 10.4049/jimmunol.1900434.
    >> Share

    January 2020
  127. MAHAJAN S, Mellins ED, Faccio R
    Diacylglycerol Kinase zeta Regulates Macrophage Responses in Juvenile Arthritis and Cytokine Storm Syndrome Mouse Models.
    J Immunol. 2020;204:137-146.
    >> Share

    July 2019
  128. MARTINOV T, Swanson LA, Breed ER, Tucker CG, et al
    Programmed Death-1 Restrains the Germinal Center in Type 1 Diabetes.
    J Immunol. 2019 Jul 19. pii: jimmunol.1801535. doi: 10.4049/jimmunol.1801535.
    >> Share

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