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Articles published in
J Immunol
    April 2024
  1. LORANT AK, Yoshida AE, Gilbertson EA, Chu T, et al
    Integrin alphavbeta3 Limits Cytokine Production by Plasmacytoid Dendritic Cells and Restricts TLR-Driven Autoimmunity.
    J Immunol. 2024 Apr 12:ji2300290. doi: 10.4049/jimmunol.2300290.
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  2. DE GEORGE DJ, Jhala G, Selck C, Trivedi P, et al
    Altering beta Cell Antigen Exposure to Exhausted CD8+ T Cells Prevents Autoimmune Diabetes in Mice.
    J Immunol. 2024 Apr 8:ji2300785. doi: 10.4049/jimmunol.2300785.
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  3. FRANK C, Salapa HE, Allen KJH, Levin MC, et al
    Antibody-Mediated Depletion of Autoreactive T Lymphocytes through PD-1 Improves Disease Outcomes and Visualizes T Cell Activation in Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2024 Apr 5:ji2300751. doi: 10.4049/jimmunol.2300751.
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  4. WU J, Han K, Sack MN
    Targeting NAD+ Metabolism to Modulate Autoimmunity and Inflammation.
    J Immunol. 2024;212:1043-1050.
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    March 2024
  5. COSTANZO A, Clarke D, Holt M, Sharma S, et al
    Repositioning the Early Pathology of Type 1 Diabetes to the Extraislet Vasculature.
    J Immunol. 2024 Mar 1:ji2300769. doi: 10.4049/jimmunol.2300769.
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    February 2024
  6. KAGOHASHI K, Sasaki Y, Ozawa K, Tsuchiya T, et al
    Role of Signal-Transducing Adaptor Protein-1 for T Cell Activation and Pathogenesis of Autoimmune Demyelination and Airway Inflammation.
    J Immunol. 2024 Feb 5:ji2300202. doi: 10.4049/jimmunol.2300202.
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  7. DUAN S, Li Q, Wang F, Kuang W, et al
    Single-Cell Transcriptomes and Immune Repertoires Reveal the Cell State and Molecular Changes in Pemphigus Vulgaris.
    J Immunol. 2024;212:375-388.
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    January 2024
  8. DAR AA, Ortega Y, Aktas S, Wu K, et al
    CRL4b Inhibition Ameliorates Experimental Autoimmune Encephalomyelitis Progression.
    J Immunol. 2024 Jan 24:ji2300754. doi: 10.4049/jimmunol.2300754.
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  9. YANDAMURI SS, Filipek B, Lele N, Cohen I, et al
    A Noncanonical CD56dimCD16dim/- NK Cell Subset Indicative of Prior Cytotoxic Activity Is Elevated in Patients with Autoantibody-Mediated Neurologic Diseases.
    J Immunol. 2024 Jan 22:ji2300015. doi: 10.4049/jimmunol.2300015.
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  10. TOMALA J, Cao SD, Spangler JB
    Engineering Anticytokine Antibodies for Immune Modulation.
    J Immunol. 2024;212:225-234.
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  11. HAN K, Xu J, Xie F, Crowther J, et al
    Engineering Strategies to Modulate the Gut Microbiome and Immune System.
    J Immunol. 2024;212:208-215.
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  12. KLUG N, Burke J, Scott E
    Rational Engineering of Islet Tolerance via Biomaterial-Mediated Immune Modulation.
    J Immunol. 2024;212:216-224.
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    December 2023
  13. FLYNN AL, Gans J, Escobedo J, Zhu C, et al
    RGS1 Modulates Autophagic and Metabolic Programs and Is a Critical Mediator of Human Regulatory T Cell Function.
    J Immunol. 2023;211:1656-1668.
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    November 2023
  14. SONI C, Makita S, Eichinger A, Serpas L, et al
    Cutting Edge: TLR2 Signaling in B Cells Promotes Autoreactivity to DNA via IL-6 Secretion.
    J Immunol. 2023;211:1475-1480.
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  15. LU Y, Chiang J, Zhang R, Roche PA, et al
    TRAF6 and TRAF2/3 Binding Motifs in CD40 Differentially Regulate B Cell Function in T-Dependent Antibody Responses and Dendritic Cell Function in Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2023 Nov 3:ji2300607. doi: 10.4049/jimmunol.2300607.
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  16. MONSON N, Smith C, Greenberg H, Plumb P, et al
    VH2+ Antigen-Experienced B Cells in the Cerebrospinal Fluid Are Expanded and Enriched in Pediatric Anti-NMDA Receptor Encephalitis.
    J Immunol. 2023;211:1332-1339.
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  17. AKBAR I, Tang R, Baillargeon J, Roy AP, et al
    Cutting Edge: Serpine1 Negatively Regulates Th1 Cell Responses in Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2023 Nov 1:ji2300526. doi: 10.4049/jimmunol.2300526.
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    October 2023
  18. RACINE JJ, Misherghi A, Dwyer JR, Maser R, et al
    HLA-DQ8 Supports Development of Insulitis Mediated by Insulin-Reactive Human TCR-Transgenic T Cells in Nonobese Diabetic Mice.
    J Immunol. 2023 Oct 25:ji2300303. doi: 10.4049/jimmunol.2300303.
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  19. SOUKOU-WARGALLA S, Kilian C, Velasquez LN, Machicote A, et al
    Tr1 Cells Emerge and Suppress Effector Th17 Cells in Glomerulonephritis.
    J Immunol. 2023 Oct 18:ji2300305. doi: 10.4049/jimmunol.2300305.
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  20. JORDAN TJM, Chen J, Li N, Burette S, et al
    The Eotaxin-1/CCR3 Axis and Matrix Metalloproteinase-9 Are Critical in Anti-NC16A IgE-Induced Bullous Pemphigoid.
    J Immunol. 2023;211:1216-1223.
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  21. GILLES A, Hu L, Virdis F, Sant'Angelo DB, et al
    The MHC Class II Antigen-Processing and Presentation Pathway Is Dysregulated in Type 1 Diabetes.
    J Immunol. 2023 Oct 9:ji2300213. doi: 10.4049/jimmunol.2300213.
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  22. MOK MY, Luo CY, Huang FP, Kong WY, et al
    IL-33 Orchestrated the Interaction and Immunoregulatory Functions of Alternatively Activated Macrophages and Regulatory T Cells In Vitro.
    J Immunol. 2023;211:1134-1143.
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    September 2023
  23. NEW JS, Dizon BLP, King RG, Greenspan NS, et al
    B-1 B Cell-Derived Natural Antibodies against N-Acetyl-d-Glucosamine Suppress Autoimmune Diabetes Pathogenesis.
    J Immunol. 2023 Sep 25:ji2300264. doi: 10.4049/jimmunol.2300264.
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  24. MORIN F, Singh N, Mdzomba JB, Dumas A, et al
    Correction: Conditional Deletions of Hdc Confirm Roles of Histamine in Anaphylaxis and Circadian Activity but Not in Autoimmune Encephalomyelitis.
    J Immunol. 2023 Sep 11:ji2300549. doi: 10.4049/jimmunol.2300549.
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  25. PARK YP, Roach T, Soh S, Zeumer-Spataro L, et al
    Molecular Mechanisms of Lupus Susceptibility Allele PBX1D.
    J Immunol. 2023;211:727-734.
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    August 2023
  26. WILHELM CR, Upadhye MA, Eschbacher KL, Karandikar NJ, et al
    Proteolipid Protein-Induced Mouse Model of Multiple Sclerosis Requires B Cell-Mediated Antigen Presentation.
    J Immunol. 2023 Aug 7:ji2200721. doi: 10.4049/jimmunol.2200721.
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    July 2023
  27. MATSUYAMA S, Yamamoto R, Murakami K, Takahashi N, et al
    GM-CSF Promotes the Survival of Peripheral-Derived Myeloid Cells in the Central Nervous System for Pain-Induced Relapse of Neuroinflammation.
    J Immunol. 2023;211:34-42.
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    June 2023
  28. JAIN RW, Elliott DA, Yong VW
    Single Cell Analysis of High-Parameter Histology Images Using Histoflow Cytometry.
    J Immunol. 2023;210:2038-2049.
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  29. SHEININ M, Mondal S, Roy A, Gorai S, et al
    Suppression of Experimental Autoimmune Encephalomyelitis in Mice by beta-Hydroxy beta-Methylbutyrate, a Body-Building Supplement in Humans.
    J Immunol. 2023 Jun 14:ji2200267. doi: 10.4049/jimmunol.2200267.
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  30. ZHANG W, Mackay CR, Gershwin ME
    Immunomodulatory Effects of Microbiota-Derived Short-Chain Fatty Acids in Autoimmune Liver Diseases.
    J Immunol. 2023;210:1629-1639.
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  31. SINGH SP, Parween F, Edara N, Zhang HH, et al
    Human CCR6+ Th Cells Show Both an Extended Stable Gradient of Th17 Activity and Imprinted Plasticity.
    J Immunol. 2023;210:1700-1716.
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  32. BUZZELLI AA, McWilliams IL, Shin B, Bryars MT, et al
    Intrinsic STAT4 Expression Controls Effector CD4 T Cell Migration and Th17 Pathogenicity.
    J Immunol. 2023;210:1667-1676.
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    May 2023
  33. RENSHAW L, Kim P, Crici M, Fazelinia H, et al
    The Ubiquitin Ligase Itch Skews Light Zone Selection in Germinal Centers.
    J Immunol. 2023;210:1473-1481.
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    April 2023
  34. GREILACH SA, McIntyre LL, Nguyen QH, Silva J, et al
    Presentation of Human Neural Stem Cell Antigens Drives Regulatory T Cell Induction.
    J Immunol. 2023 Apr 21:ji2200798. doi: 10.4049/jimmunol.2200798.
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  35. LEE PY, Cron RQ
    The Multifaceted Immunology of Cytokine Storm Syndrome.
    J Immunol. 2023;210:1015-1024.
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  36. THOMPSON JW, Hu R, Huffaker TB, Ramstead AG, et al
    MicroRNA-155 Plays Selective Cell-Intrinsic Roles in Brain-Infiltrating Immune Cell Populations during Neuroinflammation.
    J Immunol. 2023;210:926-934.
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    March 2023
  37. MOREEWS M, Mathieu AL, Pouxvielh K, Reuschle Q, et al
    mTOR Activation Underlies Enhanced B Cell Proliferation and Autoimmunity in PrkcdG510S/G510S Mice.
    J Immunol. 2023 Mar 24:ji2200818. doi: 10.4049/jimmunol.2200818.
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  38. MANJILI MH
    The Adaptation Model of Immunity: Signal IV Matters Most in Determining the Functional Outcomes of Immune Responses.
    J Immunol. 2023;210:521-530.
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    February 2023
  39. ABBOUD G, Choi SC, Zhang X, Park YP, et al
    Glucose Requirement of Antigen-Specific Autoreactive B Cells and CD4+ T Cells.
    J Immunol. 2023;210:377-388.
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  40. CIECKO AE, Wang Y, Harleston S, Drewek A, et al
    Heterogeneity of Islet-Infiltrating IL-21+ CD4 T Cells in a Mouse Model of Type 1 Diabetes.
    J Immunol. 2023 Feb 10:ji2200712. doi: 10.4049/jimmunol.2200712.
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  41. SUBRAMANIAN K, Paul S, Libby A, Patterson J, et al
    HERV1-env Induces Unfolded Protein Response Activation in Autoimmune Liver Disease: A Potential Mechanism for Regulatory T Cell Dysfunction.
    J Immunol. 2023 Feb 1:ji2100186. doi: 10.4049/jimmunol.2100186.
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    January 2023
  42. KIM D, Rai NK, Burrows A, Kim S, et al
    IFN-Induced Protein with Tetratricopeptide Repeats 2 Limits Autoimmune Inflammation by Regulating Myeloid Cell Activation and Metabolic Activity.
    J Immunol. 2023 Jan 25:ji2200746. doi: 10.4049/jimmunol.2200746.
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  43. RAPARIA C, Quach TD, Zeumer-Spataro L, Choi SC, et al
    Combination CTLA4Ig and Anti-CD40 Ligand Treatment Modifies T and B Cell Metabolic Profiles and Promotes B Cell Receptor Remodeling in a Mouse Model of Systemic Lupus Erythematosus.
    J Immunol. 2023 Jan 16:ji2100792. doi: 10.4049/jimmunol.2100792.
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  44. HODGSON R, Crockford TL, Bhandari A, Kepple JD, et al
    Prolidase Deficiency Causes Spontaneous T Cell Activation and Lupus-Like Autoimmunity.
    J Immunol. 2023 Jan 11:ji2200212. doi: 10.4049/jimmunol.2200212.
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    December 2022
  45. LU Y, Xu M, Dorrier CE, Zhang R, et al
    CD40 Drives Central Nervous System Autoimmune Disease by Inducing Complementary Effector Programs via B Cells and Dendritic Cells.
    J Immunol. 2022;209:2083-2092.
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  46. EMRALINO FL, Satoh S, Sakai N, Takami M, et al
    Double-Stranded RNA Induces Mortality in an MDA5-Mediated Type I Interferonopathy Model.
    J Immunol. 2022;209:2093-2103.
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    November 2022
  47. WU Y, Chen D, Hu Y, Zhang S, et al
    Ring Finger Protein 215 Negatively Regulates Type I IFN Production via Blocking NF-kappaB p65 Activation.
    J Immunol. 2022;209:2012-2021.
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  48. MATTER AL, Liggitt D, Goverman JM
    B Cells Drive MHC Class I-Restricted CD4 T Cells to Induce Spontaneous Central Nervous System Autoimmunity.
    J Immunol. 2022;209:1880-1891.
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  49. WU Y, Chen D, Hu Y, Zhang S, et al
    Ring Finger Protein 215 Negatively Regulates Type I IFN Production via Blocking NF-kappaB p65 Activation.
    J Immunol. 2022;209:2012-2021.
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  50. MURATA R, Kinoshita S, Matsuda K, Kawaguchi A, et al
    G307S DNAM-1 Mutation Exacerbates Autoimmune Encephalomyelitis via Enhancing CD4(+) T Cell Activation.
    J Immunol. 2022 Nov 2. pii: jimmunol.2200608. doi: 10.4049/jimmunol.2200608.
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  51. MURATA R, Kinoshita S, Matsuda K, Kawaguchi A, et al
    G307S DNAM-1 Mutation Exacerbates Autoimmune Encephalomyelitis via Enhancing CD4+ T Cell Activation.
    J Immunol. 2022 Nov 2:ji2200608. doi: 10.4049/jimmunol.2200608.
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    October 2022
  52. LU Y, Xu M, Dorrier CE, Zhang R, et al
    CD40 Drives Central Nervous System Autoimmune Disease by Inducing Complementary Effector Programs via B Cells and Dendritic Cells.
    J Immunol. 2022 Oct 12. pii: jimmunol.2200439. doi: 10.4049/jimmunol.2200439.
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  53. MATTER AL, Liggitt D, Goverman JM
    B Cells Drive MHC Class I-Restricted CD4 T Cells to Induce Spontaneous Central Nervous System Autoimmunity.
    J Immunol. 2022 Oct 7. pii: jimmunol.2200494. doi: 10.4049/jimmunol.2200494.
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  54. SONG J, Anderson W, Hu A, Obata-Ninomiya K, et al
    CBLB Deficiency in Human CD4(+) T Cells Results in Resistance to T Regulatory Suppression through Multiple Mechanisms.
    J Immunol. 2022;209:1260-1271.
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    September 2022
  55. PARHAM KA, Tan XXS, Morelli DM, Chowdhury L, et al
    Pre-Germinal Center Interactions with T Cells Are Natural Checkpoints to Limit Autoimmune B Cell Responses.
    J Immunol. 2022 Sep 19. pii: jimmunol.2200534. doi: 10.4049/jimmunol.2200534.
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  56. ZHANG Q, Liu Y, Liao J, Wu R, et al
    Deficiency of p53 Causes the Inadequate Expression of miR-1246 in B Cells of Systemic Lupus Erythematosus.
    J Immunol. 2022 Sep 9. pii: jimmunol.2200307. doi: 10.4049/jimmunol.2200307.
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  57. GAO M, Liu S, Chatham WW, Mountz JD, et al
    IL-4-Induced Quiescence of Resting Naive B Cells Is Disrupted in Systemic Lupus Erythematosus.
    J Immunol. 2022 Sep 7. pii: jimmunol.2200409. doi: 10.4049/jimmunol.2200409.
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    August 2022
  58. WOODS J, Pemberton SE, Largent AD, Chiang K, et al
    Cutting Edge: Systemic Autoimmunity in Murine STAT3 Gain-of-Function Syndrome Is Characterized by Effector T Cell Expansion in the Absence of Overt Regulatory T Cell Dysfunction.
    J Immunol. 2022 Aug 22. pii: jimmunol.2100920. doi: 10.4049/jimmunol.2100920.
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  59. TAYLOR TC, Li Y, Li DD, Majumder S, et al
    Arid5a Mediates an IL-17-Dependent Pathway That Drives Autoimmunity but Not Antifungal Host Defense.
    J Immunol. 2022 Aug 8. pii: jimmunol.2200132. doi: 10.4049/jimmunol.2200132.
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  60. ZOU YR, Davidson A
    Nucleic Acid Sensing and Systemic Lupus Erythematosus: The Danger of Self.
    J Immunol. 2022;209:431-433.
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    July 2022
  61. CAO R, Li Z, Wu C, Ji S, et al
    Identification of a Small Molecule with Strong Anti-Inflammatory Activity in Experimental Autoimmune Encephalomyelitis and Sepsis through Blocking Gasdermin D Activation.
    J Immunol. 2022 Jul 29. pii: jimmunol.2100977. doi: 10.4049/jimmunol.2100977.
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    June 2022
  62. CHANG J, Bouchard A, Bouklouch Y, Panneton V, et al
    ICOS-Deficient Regulatory T Cells Can Prevent Spontaneous Autoimmunity but Are Impaired in Controlling Acute Inflammation.
    J Immunol. 2022 Jun 27. pii: jimmunol.2100897. doi: 10.4049/jimmunol.2100897.
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  63. DWYER JR, Racine JJ, Chapman HD, Quinlan A, et al
    Nfkbid Overexpression in Nonobese Diabetic Mice Elicits Complete Type 1 Diabetes Resistance in Part Associated with Enhanced Thymic Deletion of Pathogenic CD8 T Cells and Increased Numbers and Activity of Regulatory T Cells.
    J Immunol. 2022 Jun 27. pii: jimmunol.2100558. doi: 10.4049/jimmunol.2100558.
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  64. KIAPOUR N, Wu B, Wang Y, Seyedsadr M, et al
    Therapeutic Effect of Anti-CD52 Monoclonal Antibody in Multiple Sclerosis and Its Animal Models Is Mediated via T Regulatory Cells.
    J Immunol. 2022 Jun 24. pii: jimmunol.2100176. doi: 10.4049/jimmunol.2100176.
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  65. PODOJIL JR, Genardi S, Chiang MY, Kakade S, et al
    Tolerogenic Immune-Modifying Nanoparticles Encapsulating Multiple Recombinant Pancreatic beta Cell Proteins Prevent Onset and Progression of Type 1 Diabetes in Nonobese Diabetic Mice.
    J Immunol. 2022 Jun 20. pii: jimmunol.2200208. doi: 10.4049/jimmunol.2200208.
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  66. MEIER LA, Faragher JL, Osinski V, Auger JL, et al
    CD47 Promotes Autoimmune Valvular Carditis by Impairing Macrophage Efferocytosis and Enhancing Cytokine Production.
    J Immunol. 2022;208:2643-2651.
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  67. WONG KL, Li Z, Ma F, Wang D, et al
    SM03, an Anti-CD22 Antibody, Converts Cis-to-Trans Ligand Binding of CD22 against alpha2,6-Linked Sialic Acid Glycans and Immunomodulates Systemic Autoimmune Diseases.
    J Immunol. 2022 Jun 10. pii: jimmunol.2100820. doi: 10.4049/jimmunol.2100820.
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    May 2022
  68. AKAMA-GARREN EH, Carroll MC
    Lupus Susceptibility Loci Predispose Mice to Clonal Lymphocytic Responses and Myeloid Expansion.
    J Immunol. 2022;208:2403-2424.
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    April 2022
  69. KUMAR P, Balakrishnan S, Surendra Lele S, Setty S, et al
    Restoration of Follicular T-Regulatory/Helper Cell Balance by OX40L-JAG1 Cotreatment Suppresses Lupus Nephritis in NZBWF1/j Mice.
    J Immunol. 2022 Apr 25. pii: jimmunol.2200057. doi: 10.4049/jimmunol.2200057.
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    March 2022
  70. BEN NASR M, Robbins D, Parone P, Usuelli V, et al
    Pharmacologically Enhanced Regulatory Hematopoietic Stem Cells Revert Experimental Autoimmune Diabetes and Mitigate Other Autoimmune Disorders.
    J Immunol. 2022 Mar 23. pii: jimmunol.2100949. doi: 10.4049/jimmunol.2100949.
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  71. RICKASSEL C, Gnirck AC, Shaikh N, Adamiak V, et al
    Conventional NK Cells and Type 1 Innate Lymphoid Cells Do Not Influence Pathogenesis of Experimental Glomerulonephritis.
    J Immunol. 2022 Mar 16. pii: jimmunol.2101012. doi: 10.4049/jimmunol.2101012.
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  72. YUZEFPOLSKIY Y, Morawski P, Fahning M, Speake C, et al
    Cutting Edge: Effect of Disease-Modifying Therapies on SARS-CoV-2 Vaccine-Induced Immune Responses in Multiple Sclerosis Patients.
    J Immunol. 2022 Mar 14. pii: jimmunol.2101142. doi: 10.4049/jimmunol.2101142.
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  73. LV J, Han M, Xiang Z, Gong R, et al
    Chlorzoxazone Alleviates Experimental Autoimmune Encephalomyelitis via Inhibiting IL-6 Secretion of Dendritic Cells.
    J Immunol. 2022 Mar 11. pii: jimmunol.2100169. doi: 10.4049/jimmunol.2100169.
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  74. CHYUAN IT, Chu CL, Hsu CL, Pan MH, et al
    T Cell-Specific Deletion of TRAIL Receptor Reveals Its Critical Role for Regulating Pathologic T Cell Activation and Disease Induction in Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2022 Mar 9. pii: jimmunol.2100788. doi: 10.4049/jimmunol.2100788.
    >> Share

  75. KAWANO S, Mitoma H, Inokuchi S, Yamauchi Y, et al
    TNFR2 Signaling Enhances Suppressive Abilities of Human Circulating T Follicular Regulatory Cells.
    J Immunol. 2022;208:1057-1065.
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  76. SUN D, Chan N, Shao H, Born WK, et al
    gammadelta T Cells Activated in Different Inflammatory Environments Are Functionally Distinct.
    J Immunol. 2022;208:1224-1231.
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    February 2022
  77. MANIVASAGAM S, Williams JL, Vollmer LL, Bollman B, et al
    Targeting IFN-lambda Signaling Promotes Recovery from Central Nervous System Autoimmunity.
    J Immunol. 2022 Feb 18. pii: jimmunol.2101041. doi: 10.4049/jimmunol.2101041.
    >> Share

  78. KIM S, Boehme L, Nel L, Casian A, et al
    Defective STAT5 Activation and Aberrant Expression of BCL6 in Naive CD4 T Cells Enhances Follicular Th Cell-like Differentiation in Patients with Granulomatosis with Polyangiitis.
    J Immunol. 2022;208:807-818.
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  79. JIANG R, Qin Y, Wang Y, Xu X, et al
    Dynamic Number and Function of IL-10-Producing Regulatory B Cells in the Immune Microenvironment at Distinct Stages of Type 1 Diabetes.
    J Immunol. 2022 Feb 9. pii: jimmunol.2100357. doi: 10.4049/jimmunol.2100357.
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  80. NOMURA H, Wada N, Takahashi H, Kase Y, et al
    IgM to IgG Class Switching Is a Necessary Step for Pemphigus Phenotype Induction in Desmoglein 3-Specific B Cell Receptor Knock-in Mouse.
    J Immunol. 2022;208:582-593.
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    January 2022
  81. JORGE AM, Lao T, Kim R, Licciardi S, et al
    SCARF1-Induced Efferocytosis Plays an Immunomodulatory Role in Humans, and Autoantibodies Targeting SCARF1 Are Produced in Patients with Systemic Lupus Erythematosus.
    J Immunol. 2022 Jan 26. pii: jimmunol.2100532. doi: 10.4049/jimmunol.2100532.
    >> Share

  82. LOMBARD-VADNAIS F, Collin R, Daudelin JF, Chabot-Roy G, et al
    The Idd2 Locus Confers Prominent Resistance to Autoimmune Diabetes.
    J Immunol. 2022 Jan 17. pii: jimmunol.2100456. doi: 10.4049/jimmunol.2100456.
    >> Share

  83. JONES BE, Maerz MD, Bahnson HT, Somasundaram A, et al
    Fewer LAG-3(+) T Cells in Relapsing-Remitting Multiple Sclerosis and Type 1 Diabetes.
    J Immunol. 2022 Jan 12. pii: jimmunol.2100850. doi: 10.4049/jimmunol.2100850.
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    December 2021
  84. MERLO LMF, Peng W, DuHadaway JB, Montgomery JD, et al
    The Immunomodulatory Enzyme IDO2 Mediates Autoimmune Arthritis through a Nonenzymatic Mechanism.
    J Immunol. 2021 Dec 29. pii: jimmunol.2100705. doi: 10.4049/jimmunol.2100705.
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  85. RENNA V, Surova E, Khadour A, Datta M, et al
    Defective Allelic Exclusion by IgD in the Absence of Autoantigen.
    J Immunol. 2021 Dec 20. pii: jimmunol.2100726. doi: 10.4049/jimmunol.2100726.
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  86. MONTEITH AJ, Miller JM, Williams JM, Voss K, et al
    Altered Mitochondrial Homeostasis during Systemic Lupus Erythematosus Impairs Neutrophil Extracellular Trap Formation Rendering Neutrophils Ineffective at Combating Staphylococcus aureus.
    J Immunol. 2021 Dec 20. pii: jimmunol.2100752. doi: 10.4049/jimmunol.2100752.
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  87. INOUE M, Nakahama T, Yamasaki R, Shibuya T, et al
    An Aicardi-Goutieres Syndrome-Causative Point Mutation in Adar1 Gene Invokes Multiorgan Inflammation and Late-Onset Encephalopathy in Mice.
    J Immunol. 2021;207:3016-3027.
    >> Share

  88. CZEH M, Stable S, Kramer S, Tepe L, et al
    DNMT1 Deficiency Impacts on Plasmacytoid Dendritic Cells in Homeostasis and Autoimmune Disease.
    J Immunol. 2021 Dec 13. pii: jimmunol.2100624. doi: 10.4049/jimmunol.2100624.
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    November 2021
  89. WHITTINGTON KB, Prislovsky A, Beaty J, Albritton L, et al
    CD8(+) T Cells Expressing an HLA-DR1 Chimeric Antigen Receptor Target Autoimmune CD4(+) T Cells in an Antigen-Specific Manner and Inhibit the Development of Autoimmune Arthritis.
    J Immunol. 2021 Nov 24. pii: jimmunol.2100643. doi: 10.4049/jimmunol.2100643.
    >> Share

  90. O'CONNELL P, Blake MK, Godbehere S, Aldhamen YA, et al
    Absence of ERAP1 in B Cells Increases Susceptibility to Central Nervous System Autoimmunity, Alters B Cell Biology, and Mechanistically Explains Genetic Associations between ERAP1 and Multiple Sclerosis.
    J Immunol. 2021 Nov 22. pii: jimmunol.2100813. doi: 10.4049/jimmunol.2100813.
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  91. LEE J, Cullum E, Stoltz K, Bachmann N, et al
    Mouse Homologue of Human HLA-DO Does Not Preempt Autoimmunity but Controls Murine Gammaherpesvirus MHV68.
    J Immunol. 2021 Nov 22. pii: jimmunol.2100650. doi: 10.4049/jimmunol.2100650.
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  92. HU Y, Chen G, Huang J, Li Z, et al
    The Calcium Channel Inhibitor Nimodipine Shapes the Uveitogenic T Cells and Protects Mice from Experimental Autoimmune Uveitis through the p38-MAPK Signaling Pathway.
    J Immunol. 2021 Nov 19. pii: jimmunol.2100568. doi: 10.4049/jimmunol.2100568.
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  93. ALLENSPACH EJ, Shubin NJ, Cerosaletti K, Mikacenic C, et al
    The Autoimmune Risk R262W Variant of the Adaptor SH2B3 Improves Survival in Sepsis.
    J Immunol. 2021 Nov 5. pii: jimmunol.2100454. doi: 10.4049/jimmunol.2100454.
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  94. CHUNG H, Komada T, Lau A, Chappellaz M, et al
    AIM2 Suppresses Inflammation and Epithelial Cell Proliferation during Glomerulonephritis.
    J Immunol. 2021 Nov 5. pii: jimmunol.2100483. doi: 10.4049/jimmunol.2100483.
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  95. TSE BCY, Ireland RA, Lee JY, Marsh-Wakefield F, et al
    Exposure to Systemic Immunosuppressive Ultraviolet Radiation Alters T Cell Recirculation through Sphingosine-1-Phosphate.
    J Immunol. 2021;207:2278-2287.
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    October 2021
  96. BARNAS JL, Albrecht J, Meednu N, Alzamareh DF, et al
    B Cell Activation and Plasma Cell Differentiation Are Promoted by IFN-lambda in Systemic Lupus Erythematosus.
    J Immunol. 2021 Oct 27. pii: jimmunol.2100339. doi: 10.4049/jimmunol.2100339.
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  97. WELIWITIGODA A, Palle P, Gessner M, Hubbard NW, et al
    Cutting Edge: DOCK8 Regulates a Subset of Dendritic Cells That Is Critical for the Development of Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2021 Oct 18. pii: jimmunol.2001294. doi: 10.4049/jimmunol.2001294.
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  98. LI M, Itoh A, Xi J, Yu C, et al
    Enhancing Antigen Presentation and Inducing Antigen-Specific Immune Tolerance with Amphiphilic Peptides.
    J Immunol. 2021;207:2051-2059.
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    September 2021
  99. CHIANG K, Largent AD, Arkatkar T, Thouvenel CD, et al
    Cutting Edge: A Threshold of B Cell Costimulatory Signals Is Required for Spontaneous Germinal Center Formation in Autoimmunity.
    J Immunol. 2021 Sep 29. pii: jimmunol.2100548. doi: 10.4049/jimmunol.2100548.
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  100. ARAKAWA A, Reeves E, Vollmer S, Arakawa Y, et al
    ERAP1 Controls the Autoimmune Response against Melanocytes in Psoriasis by Generating the Melanocyte Autoantigen and Regulating Its Amount for HLA-C*06:02 Presentation.
    J Immunol. 2021 Sep 27. pii: jimmunol.2100686. doi: 10.4049/jimmunol.2100686.
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  101. MANDEL-BREHM C, Fichtner ML, Jiang R, Winton VJ, et al
    Elevated N-Linked Glycosylation of IgG V Regions in Myasthenia Gravis Disease Subtypes.
    J Immunol. 2021 Sep 20. pii: jimmunol.2100225. doi: 10.4049/jimmunol.2100225.
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  102. CIECKO AE, Schauder DM, Foda B, Petrova G, et al
    Self-Renewing Islet TCF1(+) CD8 T Cells Undergo IL-27-Controlled Differentiation to Become TCF1(-) Terminal Effectors during the Progression of Type 1 Diabetes.
    J Immunol. 2021 Sep 10. pii: jimmunol.2100362. doi: 10.4049/jimmunol.2100362.
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  103. ZHOU M, Dascani P, Ding C, Kos JT, et al
    Integrin CD11b Negatively Regulates B Cell Receptor Signaling to Shape Humoral Response during Immunization and Autoimmunity.
    J Immunol. 2021 Sep 1. pii: jimmunol.2100070. doi: 10.4049/jimmunol.2100070.
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    August 2021
  104. LEE DSW, Yam JY, Grasmuck C, Dasoveanu D, et al
    CCR6 Expression on B Cells Is Not Required for Clinical or Pathological Presentation of MOG Protein-Induced Experimental Autoimmune Encephalomyelitis despite an Altered Germinal Center Response.
    J Immunol. 2021 Aug 16. pii: jimmunol.2001413. doi: 10.4049/jimmunol.2001413.
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  105. BOULET S, Odagiu L, Dong M, Lebel ME, et al
    NR4A3 Mediates Thymic Negative Selection.
    J Immunol. 2021;207:1055-1064.
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  106. MANOHARAN I, Swafford D, Shanmugam A, Patel N, et al
    Activation of Transcription Factor 4 in Dendritic Cells Controls Th1/Th17 Responses and Autoimmune Neuroinflammation.
    J Immunol. 2021 Aug 4. pii: jimmunol.2100010. doi: 10.4049/jimmunol.2100010.
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  107. PERRY DJ, Peters LD, Lakshmi PS, Zhang L, et al
    Overexpression of the PTPN22 Autoimmune Risk Variant LYP-620W Fails to Restrain Human CD4(+) T Cell Activation.
    J Immunol. 2021;207:849-859.
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    July 2021
  108. GYAPON-QUAST F, Goicoechea de Jorge E, Malik T, Wu N, et al
    Defining the Glycosaminoglycan Interactions of Complement Factor H-Related Protein 5.
    J Immunol. 2021;207:534-541.
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  109. VAN ASTEN SD, Unger PP, Marsman C, Bliss S, et al
    Soluble FAS Ligand Enhances Suboptimal CD40L/IL-21-Mediated Human Memory B Cell Differentiation into Antibody-Secreting Cells.
    J Immunol. 2021;207:449-458.
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  110. Top Reads.
    J Immunol. 2021;207:1-2.
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    June 2021
  111. CHURCH ME, Ceja G, McGeehan M, Miller MC, et al
    Meningeal B Cell Clusters Correlate with Submeningeal Pathology in a Natural Model of Multiple Sclerosis.
    J Immunol. 2021 Jun 23. pii: jimmunol.2000514. doi: 10.4049/jimmunol.2000514.
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  112. NEEDHAM EJ, Stoevesandt O, Thelin EP, Zetterberg H, et al
    Complex Autoantibody Responses Occur following Moderate to Severe Traumatic Brain Injury.
    J Immunol. 2021 Jun 18. pii: jimmunol.2001309. doi: 10.4049/jimmunol.2001309.
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  113. ZHANG J, Bouch RJ, Blekhman MG, He Z, et al
    USP19 Suppresses Th17-Driven Pathogenesis in Autoimmunity.
    J Immunol. 2021 Jun 16. pii: jimmunol.2100205. doi: 10.4049/jimmunol.2100205.
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  114. KO MK, Shao H, Kaplan HJ, Sun D, et al
    Timing Effect of Adenosine-Directed Immunomodulation on Mouse Experimental Autoimmune Uveitis.
    J Immunol. 2021 Jun 14. pii: jimmunol.2100182. doi: 10.4049/jimmunol.2100182.
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  115. XIE JH, Zhang Y, Loubeau M, Mangan P, et al
    Mouse IL-2/CD25 Fusion Protein Induces Regulatory T Cell Expansion and Immune Suppression in Preclinical Models of Systemic Lupus Erythematosus.
    J Immunol. 2021 Jun 9. pii: jimmunol.2100078. doi: 10.4049/jimmunol.2100078.
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  116. SONODA S, Murata S, Kato H, Zakaria F, et al
    Targeting of Deciduous Tooth Pulp Stem Cell-Derived Extracellular Vesicles on Telomerase-Mediated Stem Cell Niche and Immune Regulation in Systemic Lupus Erythematosus.
    J Immunol. 2021 Jun 2. pii: jimmunol.2001312. doi: 10.4049/jimmunol.2001312.
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    May 2021
  117. SCHELL SL, Bricker KN, Fike AJ, Chodisetti SB, et al
    Context-Dependent miR-21 Regulation of TLR7-Mediated Autoimmune and Foreign Antigen-Driven Antibody-Forming Cell and Germinal Center Responses.
    J Immunol. 2021 May 26. pii: jimmunol.2001039. doi: 10.4049/jimmunol.2001039.
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  118. CHALAN P, Thomas N, Caturegli P
    Th17 Cells Contribute to the Pathology of Autoimmune Hypophysitis.
    J Immunol. 2021 May 19. pii: jimmunol.2001073. doi: 10.4049/jimmunol.2001073.
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  119. CAI H, Liu X, Zhang F, Han QY, et al
    G3BP1 Inhibition Alleviates Intracellular Nucleic Acid-Induced Autoimmune Responses.
    J Immunol. 2021;206:2453-2467.
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  120. HE R, Wu S, Gao R, Chen J, et al
    Identification of a Long Noncoding RNA TRAF3IP2-AS1 as Key Regulator of IL-17 Signaling through the SRSF10-IRF1-Act1 Axis in Autoimmune Diseases.
    J Immunol. 2021;206:2353-2365.
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  121. Top Reads.
    J Immunol. 2021;206:2249.
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  122. LI Q, Feng C, Li L, Xu G, et al
    Lipid Receptor G2A-Mediated Signal Pathway Plays a Critical Role in Inflammatory Response by Promoting Classical Macrophage Activation.
    J Immunol. 2021;206:2338-2352.
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    April 2021
  123. INOUE M, Yamashita K, Tsuji Y, Miki M, et al
    Characterization of a TNFR2-Selective Agonistic TNF-alpha Mutant and Its Derivatives as an Optimal Regulatory T Cell Expander.
    J Immunol. 2021;206:1740-1751.
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  124. PAN W, Nagpal K, Suarez-Fueyo A, Ferretti A, et al
    The Regulatory Subunit PPP2R2A of PP2A Enhances Th1 and Th17 Differentiation through Activation of the GEF-H1/RhoA/ROCK Signaling Pathway.
    J Immunol. 2021;206:1719-1728.
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  125. MORIN F, Singh N, Mdzomba JB, Dumas A, et al
    Conditional Deletions of Hdc Confirm Roles of Histamine in Anaphylaxis and Circadian Activity but Not in Autoimmune Encephalomyelitis.
    J Immunol. 2021 Apr 12. pii: jimmunol.2000719. doi: 10.4049/jimmunol.2000719.
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  126. JOHNSON BM, Uchimura T, Gallovic MD, Thamilarasan M, et al
    STING Agonist Mitigates Experimental Autoimmune Encephalomyelitis by Stimulating Type I IFN-Dependent and -Independent Immune-Regulatory Pathways.
    J Immunol. 2021 Apr 5. pii: jimmunol.2001317. doi: 10.4049/jimmunol.2001317.
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  127. LANGRISH CL, Bradshaw JM, Francesco MR, Owens TD, et al
    Preclinical Efficacy and Anti-Inflammatory Mechanisms of Action of the Bruton Tyrosine Kinase Inhibitor Rilzabrutinib for Immune-Mediated Disease.
    J Immunol. 2021;206:1454-1468.
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  128. LIN X, Tawch S, Wong HT, Roy S, et al
    Nrf2 through Aryl Hydrocarbon Receptor Regulates IL-22 Response in CD4(+) T Cells.
    J Immunol. 2021;206:1540-1548.
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  129. CHIKUMA S, Yamanaka S, Nakagawa S, Ueda MT, et al
    TRIM28 Expression on Dendritic Cells Prevents Excessive T Cell Priming by Silencing Endogenous Retrovirus.
    J Immunol. 2021;206:1528-1539.
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    March 2021
  130. BRATE AA, Boyden AW, Jensen IJ, Badovinac VP, et al
    A Functionally Distinct CXCR3(+)/IFN-gamma(+)/IL-10(+) Subset Defines Disease-Suppressive Myelin-Specific CD8 T Cells.
    J Immunol. 2021;206:1151-1160.
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  131. NANDEDKAR-KULKARNI N, Esakov E, Gregg B, Atkinson MA, et al
    Insulin Receptor-Expressing T Cells Appear in Individuals at Risk for Type 1 Diabetes and Can Move into the Pancreas in C57BL/6 Transgenic Mice.
    J Immunol. 2021 Mar 3. pii: jimmunol.1900357. doi: 10.4049/jimmunol.1900357.
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  132. CHEN L, Bai J, Peng D, Gao Y, et al
    SZB120 Exhibits Immunomodulatory Effects by Targeting eIF2alpha to Suppress Th17 Cell Differentiation.
    J Immunol. 2021;206:953-962.
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  133. THOMSON AS, Mai SH, Bouma G, Herdman M, et al
    Structure and Functional Characterization of a Humanized Anti-CCL20 Antibody following Exposure to Serum Reveals the Formation of Immune Complex That Leads to Toxicity.
    J Immunol. 2021;206:1067-1076.
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    February 2021
  134. ALLARD-CHAMARD H, Alsufyani F, Kaneko N, Xing K, et al
    CD4(+)CTLs in Fibrosing Mediastinitis Linked to Histoplasma capsulatum.
    J Immunol. 2021;206:524-530.
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    January 2021
  135. SIM JH, Ambler WG, Sollohub IF, Howlader MJ, et al
    Immune Cell-Stromal Circuitry in Lupus Photosensitivity.
    J Immunol. 2021;206:302-309.
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  136. SUMIYOSHI M, Kotani Y, Ikuta Y, Suzue K, et al
    Arf1 and Arf6 Synergistically Maintain Survival of T Cells during Activation.
    J Immunol. 2021;206:366-375.
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    November 2020
  137. BONAMI RH, Nyhoff LE, McNitt DH, Hulbert C, et al
    T-B Lymphocyte Interactions Promote Type 1 Diabetes Independently of SLAM-Associated Protein.
    J Immunol. 2020 Nov 16. pii: jimmunol.1900464. doi: 10.4049/jimmunol.1900464.
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  138. HAYES ET, Hagan CE, Khoryati L, Gavin MA, et al
    Regulatory T Cells Maintain Selective Access to IL-2 and Immune Homeostasis despite Substantially Reduced CD25 Function.
    J Immunol. 2020;205:2667-2678.
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  139. PINHEIRO DF, Szenes-Nagy AB, Maurano MM, Lietzenmayer M, et al
    Cutting Edge: Tissue Antigen Expression Levels Fine-Tune T Cell Differentiation Decisions In Vivo.
    J Immunol. 2020;205:2577-2582.
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  140. VAN DER POEL M, Hoepel W, Hamann J, Huitinga I, et al
    IgG Immune Complexes Break Immune Tolerance of Human Microglia.
    J Immunol. 2020;205:2511-2518.
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