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Articles published in
N Engl J Med
    August 2024
  1. WANDER SA, Thai JN, Wirth LJ, Soto DE, et al
    Case 26-2024: A 59-Year-Old Woman with Aphasia, Anemia, and a Breast Mass.
    N Engl J Med. 2024;391:747-757.
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  2. TURGEON AF, Fergusson DA, Clayton L, Patton MP, et al
    Liberal or Restrictive Transfusion Strategy in Patients with Traumatic Brain Injury.
    N Engl J Med. 2024;391:722-735.
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  3. ISRAEL A, Raz I, Vinker S, Magen E, et al
    Type 2 Diabetes in Patients with G6PD Deficiency.
    N Engl J Med. 2024;391:568-569.
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  4. FRANGOUL H, Hobbs WE, Locatelli F
    Studies of Exagamglogene Autotemcel - Age and Place. Reply.
    N Engl J Med. 2024;391:572.
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  5. MIN J
    Studies of Exagamglogene Autotemcel - Age and Place.
    N Engl J Med. 2024;391:571-572.
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    June 2024
  6. RISITANO AM, Kulasekararaj AG, Peffault de Latour R
    Oral Iptacopan in Paroxysmal Nocturnal Hemoglobinuria. Reply.
    N Engl J Med. 2024;390:2033-2034.
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  7. MARNAS P, Zarogiannis SG
    Oral Iptacopan in Paroxysmal Nocturnal Hemoglobinuria.
    N Engl J Med. 2024;390:2033.
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  8. HILLMEN P
    Oral Iptacopan in Paroxysmal Nocturnal Hemoglobinuria.
    N Engl J Med. 2024;390:2032-2033.
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    May 2024
  9. OLSON R, Vaidya A, Aung KK, Merz LE, et al
    Adding Insult to Injury.
    N Engl J Med. 2024;390:e51.
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  10. FRANGOUL H, Locatelli F, Sharma A, Bhatia M, et al
    Exagamglogene Autotemcel for Severe Sickle Cell Disease.
    N Engl J Med. 2024;390:1649-1662.
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  11. LOCATELLI F, Lang P, Wall D, Meisel R, et al
    Exagamglogene Autotemcel for Transfusion-Dependent beta-Thalassemia.
    N Engl J Med. 2024;390:1663-1676.
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  12. DALEY GQ
    Welcoming the Era of Gene Editing in Medicine.
    N Engl J Med. 2024;390:1642-1645.
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  13. MCCUNE JM, Kiem HP
    Extending Gene Medicines to All in Need.
    N Engl J Med. 2024;390:1721-1722.
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    April 2024
  14. LAM WK, Yip SF
    Drug-Induced Oxidative Hemolysis.
    N Engl J Med. 2024;390:1513.
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    March 2024
  15. PEFFAULT DE LATOUR R, Roth A, Kulasekararaj AG, Han B, et al
    Oral Iptacopan Monotherapy in Paroxysmal Nocturnal Hemoglobinuria.
    N Engl J Med. 2024;390:994-1008.
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  16. CARSON JL, Brooks MM, Hebert PC
    Transfusion Strategy in Myocardial Infarction and Anemia. Reply.
    N Engl J Med. 2024;390:961-962.
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  17. KHAN MS, Spertus JA, Chan PS
    Transfusion Strategy in Myocardial Infarction and Anemia.
    N Engl J Med. 2024;390:960-961.
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  18. CHAPALAIN X, Aubron C
    Transfusion Strategy in Myocardial Infarction and Anemia.
    N Engl J Med. 2024;390:960.
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    December 2023
  19. FREEDMAN SB, van de Kar NCAJ, Tarr PI
    Shiga Toxin-Producing Escherichia coli and the Hemolytic-Uremic Syndrome. Reply.
    N Engl J Med. 2023;389:2500.
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  20. JACOBS FM
    Shiga Toxin-Producing Escherichia coli and the Hemolytic-Uremic Syndrome.
    N Engl J Med. 2023;389:2499-2500.
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  21. NORIS M, Remuzzi G
    Shiga Toxin-Producing Escherichia coli and the Hemolytic-Uremic Syndrome.
    N Engl J Med. 2023;389:2499.
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    November 2023
  22. AZAR SS, Simeone FJ, Jarolimova J, Nussbaum EZ, et al
    Case 37-2023: A 29-Year-Old Man with Sickle Cell Disease and Right Hip Pain.
    N Engl J Med. 2023;389:2088-2096.
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  23. CARSON JL, Brooks MM, Hebert PC, Goodman SG, et al
    Restrictive or Liberal Transfusion Strategy in Myocardial Infarction and Anemia.
    N Engl J Med. 2023 Nov 11. doi: 10.1056/NEJMoa2307983.
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  24. ZACHRISON KS, Kamalian S, Sykes DB, Brunker PAR, et al
    Case 34-2023: A 49-Year-Old Woman with Loss of Consciousness and Thrombocytopenia.
    N Engl J Med. 2023;389:1804-1811.
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    October 2023
  25. FREEDMAN SB, van de Kar NCAJ, Tarr PI
    Shiga Toxin-Producing Escherichia coli and the Hemolytic-Uremic Syndrome.
    N Engl J Med. 2023;389:1402-1414.
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    August 2023
  26. SHARMA A, Boelens JJ, Cancio M, Hankins JS, et al
    CRISPR-Cas9 Editing of the HBG1 and HBG2 Promoters to Treat Sickle Cell Disease.
    N Engl J Med. 2023;389:820-832.
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  27. FUKUSHIMA H, Matsumoto M
    Cold Agglutinin Syndrome.
    N Engl J Med. 2023;389:642.
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  28. SCHREIBER AR, Santos J, McMahon B, Buckner TW, et al
    A Case of Fetal-Induced Graft-versus-Host Disease.
    N Engl J Med. 2023;389:668-670.
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  29. VAN BAARLE FLF, Biemond BJ, Vlaar APJ
    Platelet Transfusion in Patients with Thrombocytopenia. Reply.
    N Engl J Med. 2023;389:480.
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  30. GILSTAD CW
    Platelet Transfusion in Patients with Thrombocytopenia.
    N Engl J Med. 2023;389:479-480.
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  31. WARNER MA, Hess AS, Frank SM
    Platelet Transfusion in Patients with Thrombocytopenia.
    N Engl J Med. 2023;389:479.
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  32. SHIBUSAWA M, Tanimoto T
    Platelet Transfusion in Patients with Thrombocytopenia.
    N Engl J Med. 2023;389:478-479.
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    June 2023
  33. BLOCK J, Rashkova C, Castanon I, Zoghi S, et al
    Systemic Inflammation and Normocytic Anemia in DOCK11 Deficiency.
    N Engl J Med. 2023 Jun 21. doi: 10.1056/NEJMoa2210054.
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    April 2023
  34. VAN DIJCK R, Goncalves Silva AM, Rijneveld AW
    Luspatercept as Potential Treatment for Congenital Sideroblastic Anemia.
    N Engl J Med. 2023;388:1435-1436.
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  35. CHILDERHOSE JE, Cronin RM, Klatt MD, Schamess A, et al
    Treating Chronic Pain in Sickle Cell Disease - The Need for a Biopsychosocial Model.
    N Engl J Med. 2023;388:1349-1351.
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  36. CHASSE M, Fergusson DA, Tinmouth A, Acker JP, et al
    Effect of Donor Sex on Recipient Mortality in Transfusion.
    N Engl J Med. 2023;388:1386-1395.
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    March 2023
  37. BURTSCHER M
    Oxygen Delivery in the Treatment of Anemia.
    N Engl J Med. 2023;388:e38.
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  38. LEE AI, Heidari P, Fenves AZ, Bardia A, et al
    Case 8-2023: A 71-Year-Old Woman with Refractory Hemolytic Anemia.
    N Engl J Med. 2023;388:1032-1041.
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    December 2022
  39. MC CAUSLAND FR, Singh AK, Claggett BL, Carroll K, et al
    Daprodustat and On-Treatment Cardiovascular Events in Chronic Kidney Disease. Reply.
    N Engl J Med. 2022;387:2482-2485.
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  40. HUANG C, He Y, Li Y
    Daprodustat and On-Treatment Cardiovascular Events in Chronic Kidney Disease.
    N Engl J Med. 2022;387:2482.
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  41. ROJAS-RIVERA J, Carriazo S, Ortiz A
    Daprodustat and On-Treatment Cardiovascular Events in Chronic Kidney Disease.
    N Engl J Med. 2022;387:2481-2482.
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  42. BUNN HF
    Oxygen Delivery in the Treatment of Anemia.
    N Engl J Med. 2022;387:2362-2365.
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    September 2022
  43. DEBAUN M, Heeney M, Jackson T, Longo D, et al
    Sickle Cell Disease and Gene Therapy - Patient and Physician Perspectives.
    N Engl J Med. 2022;387:e28.
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    August 2022
  44. ZHOU AE, Travassos MA
    Bringing Sickle-Cell Treatments to Children in Sub-Saharan Africa.
    N Engl J Med. 2022;387:488-491.
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    July 2022
  45. WU YW, Comstock BA, Gonzalez FF, Mayock DE, et al
    Trial of Erythropoietin for Hypoxic-Ischemic Encephalopathy in Newborns.
    N Engl J Med. 2022;387:148-159.
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  46. NOTARO R, Luzzatto L
    Breakthrough Hemolysis in PNH with Proximal or Terminal Complement Inhibition.
    N Engl J Med. 2022;387:160-166.
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    June 2022
  47. AL-SAMKARI H, Beynon V, van Beers EJ
    Mitapivat versus Placebo for Pyruvate Kinase Deficiency. Reply.
    N Engl J Med. 2022;386:2539.
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  48. SHAH AJ, Schwartz JD, Segovia JC
    Mitapivat versus Placebo for Pyruvate Kinase Deficiency.
    N Engl J Med. 2022;386:2538-2539.
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    April 2022
  49. DI MEGLIO L, Scott A
    Iris Atrophy in Sickle Cell Disease.
    N Engl J Med. 2022;386:1646.
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  50. AL-SAMKARI H, Galacteros F, Glenthoj A, Rothman JA, et al
    Mitapivat versus Placebo for Pyruvate Kinase Deficiency.
    N Engl J Med. 2022;386:1432-1442.
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    February 2022
  51. STEINBERG MH
    Fetal-like Hemoglobin in Sickle Cell Anemia.
    N Engl J Med. 2022;386:689-691.
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  52. KANTER J, Walters MC, Krishnamurti L, Mapara MY, et al
    Biologic and Clinical Efficacy of LentiGlobin for Sickle Cell Disease.
    N Engl J Med. 2022;386:617-628.
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  53. PAYEN E
    Efficacy and Safety of Gene Therapy for beta-Thalassemia.
    N Engl J Med. 2022;386:488-490.
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  54. LOCATELLI F, Thompson AA, Kwiatkowski JL, Porter JB, et al
    Betibeglogene Autotemcel Gene Therapy for Non-beta(0)/beta(0) Genotype beta-Thalassemia.
    N Engl J Med. 2022;386:415-427.
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    January 2022
  55. PATEL A, Tillman BF
    Spur-Cell Hemolytic Anemia.
    N Engl J Med. 2022;386:e6.
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  56. SCHEINBERG P
    A New Standard Immunosuppression Regimen in Severe Aplastic Anemia.
    N Engl J Med. 2022;386:89-90.
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  57. PEFFAULT DE LATOUR R, Kulasekararaj A, Iacobelli S, Terwel SR, et al
    Eltrombopag Added to Immunosuppression in Severe Aplastic Anemia.
    N Engl J Med. 2022;386:11-23.
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    December 2021
  58. WILLETT LL, Bromberg GK, Chung R, Leaf RK, et al
    Case 38-2021: A 76-Year-Old Woman with Abdominal Pain, Weight Loss, and Memory Impairment.
    N Engl J Med. 2021;385:2378-2388.
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  59. GOYAL S, Tisdale J, Schmidt M, Kanter J, et al
    Acute Myeloid Leukemia Case after Gene Therapy for Sickle Cell Disease.
    N Engl J Med. 2021 Dec 12. doi: 10.1056/NEJMoa2109167.
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  60. PASRICHA SR, Hamadani JD, Biggs BA
    Benefits and Risks of Iron Interventions in Infants in Bangladesh. Reply.
    N Engl J Med. 2021;385:2199.
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  61. TERADA R, Sato T
    Benefits and Risks of Iron Interventions in Infants in Bangladesh.
    N Engl J Med. 2021;385:2198-2199.
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    November 2021
  62. JONASCH E, Donskov F, Iliopoulos O, Rathmell WK, et al
    Belzutifan for Renal Cell Carcinoma in von Hippel-Lindau Disease.
    N Engl J Med. 2021;385:2036-2046.
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  63. SINGH AK, Carroll K, McMurray JJV, Solomon S, et al
    Daprodustat for the Treatment of Anemia in Patients Not Undergoing Dialysis.
    N Engl J Med. 2021 Nov 5. doi: 10.1056/NEJMoa2113380.
    >> Share

  64. PARFREY P
    Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors for Anemia in CKD.
    N Engl J Med. 2021 Nov 5. doi: 10.1056/NEJMe2117100.
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  65. SINGH AK, Carroll K, Perkovic V, Solomon S, et al
    Daprodustat for the Treatment of Anemia in Patients Undergoing Dialysis.
    N Engl J Med. 2021 Nov 5. doi: 10.1056/NEJMoa2113379.
    >> Share

    October 2021
  66. HILLMEN P, Risitano AM, Peffault de Latour R
    Pegcetacoplan versus Eculizumab in PNH. Reply.
    N Engl J Med. 2021;385:1725-1726.
    >> Share

  67. GURNARI C, Pagliuca S, Maciejewski JP
    Pegcetacoplan versus Eculizumab in PNH.
    N Engl J Med. 2021;385:1725.
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  68. KULASEKARARAJ AG, Gandhi S, Brodsky RA
    Pegcetacoplan versus Eculizumab in PNH.
    N Engl J Med. 2021;385:1724-1725.
    >> Share

  69. UEDA Y, Takamori H, Nishimura JI
    Pegcetacoplan versus Eculizumab in PNH.
    N Engl J Med. 2021;385:1723-1724.
    >> Share

  70. CHERTOW GM, Eckardt KU
    Vadadustat for Anemia in Patients with Dialysis-Dependent or Non-Dialysis-Dependent Chronic Kidney Disease. Reply.
    N Engl J Med. 2021;385:e56.
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  71. BUNN HF
    Vadadustat for Anemia in Patients with Dialysis-Dependent or Non-Dialysis-Dependent Chronic Kidney Disease.
    N Engl J Med. 2021;385:e56.
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  72. HOCK H, Kelly HR, Meyerowitz EA, Frigault MJ, et al
    Case 31-2021: A 21-Year-Old Man with Sore Throat, Epistaxis, and Oropharyngeal Petechiae.
    N Engl J Med. 2021;385:1511-1520.
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  73. BERENTSEN S, Barcellini W
    Autoimmune Hemolytic Anemias.
    N Engl J Med. 2021;385:1407-1419.
    >> Share

    September 2021
  74. PASRICHA SR, Hasan MI, Braat S, Larson LM, et al
    Benefits and Risks of Iron Interventions in Infants in Rural Bangladesh.
    N Engl J Med. 2021;385:982-995.
    >> Share

  75. PICHAN C, Dhaliwal G, Cusick A, Saint S, et al
    Inadequate Support.
    N Engl J Med. 2021;385:938-944.
    >> Share

    August 2021
  76. GURNARI C, Rogers HJ
    Copper Deficiency.
    N Engl J Med. 2021;385:640.
    >> Share

    July 2021
  77. AVELAR RODRIGUEZ D, Orkin J
    An Icteric Tongue.
    N Engl J Med. 2021;385:e16.
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  78. PISCHEL L, Geirsson A, Magaldi J, Martinello RA, et al
    A Brewing Back Pain.
    N Engl J Med. 2021;385:66-72.
    >> Share

    June 2021
  79. FRANGOUL H, Ho TW, Corbacioglu S
    CRISPR-Cas9 Gene Editing for Sickle Cell Disease and beta-Thalassemia. Reply.
    N Engl J Med. 2021;384:e91.
    >> Share

  80. MEHTA J
    CRISPR-Cas9 Gene Editing for Sickle Cell Disease and beta-Thalassemia.
    N Engl J Med. 2021;384:e91.
    >> Share

  81. MEISEL R
    CRISPR-Cas9 Gene Editing for Sickle Cell Disease and beta-Thalassemia.
    N Engl J Med. 2021;384:e91.
    >> Share

  82. TAHER AT, Musallam KM, Cappellini MD
    beta-Thalassemias. Reply.
    N Engl J Med. 2021;384:2166.
    >> Share

  83. GEORGALAS I, Petrou P, Kanakis M
    beta-Thalassemias.
    N Engl J Med. 2021;384:2165-2166.
    >> Share

  84. THONG MK, Ngim CF
    beta-Thalassemias.
    N Engl J Med. 2021;384:2165.
    >> Share

    May 2021
  85. MUSTJOKI S, Young NS
    Somatic Mutations in "Benign" Disease.
    N Engl J Med. 2021;384:2039-2052.
    >> Share

  86. GIBBONS MD, Mendoza DP, Waheed A, Barshak MB, et al
    Case 14-2021: A 64-Year-Old Woman with Fever and Pancytopenia.
    N Engl J Med. 2021;384:1849-1857.
    >> Share

    April 2021
  87. LEVIN A
    Therapy for Anemia in Chronic Kidney Disease - New Interventions and New Questions.
    N Engl J Med. 2021;384:1657-1658.
    >> Share

  88. ECKARDT KU, Agarwal R, Aswad A, Awad A, et al
    Safety and Efficacy of Vadadustat for Anemia in Patients Undergoing Dialysis.
    N Engl J Med. 2021;384:1601-1612.
    >> Share

  89. CHERTOW GM, Pergola PE, Farag YMK, Agarwal R, et al
    Vadadustat in Patients with Anemia and Non-Dialysis-Dependent CKD.
    N Engl J Med. 2021;384:1589-1600.
    >> Share

  90. ROTH A, Barcellini W, D'Sa S, Miyakawa Y, et al
    Sutimlimab in Cold Agglutinin Disease.
    N Engl J Med. 2021;384:1323-1334.
    >> Share

    March 2021
  91. HILLMEN P, Szer J, Weitz I, Roth A, et al
    Pegcetacoplan versus Eculizumab in Paroxysmal Nocturnal Hemoglobinuria.
    N Engl J Med. 2021;384:1028-1037.
    >> Share

  92. OGUNWOLE SM
    Without Sanctuary.
    N Engl J Med. 2021;384:791-793.
    >> Share

    February 2021
  93. MENON BS, Teh KH
    Gum Hypertrophy from Cyclosporine.
    N Engl J Med. 2021;384:744.
    >> Share

  94. TAHER AT, Musallam KM, Cappellini MD
    beta-Thalassemias.
    N Engl J Med. 2021;384:727-743.
    >> Share

    January 2021
  95. MALECH HL
    Treatment by CRISPR-Cas9 Gene Editing - A Proof of Principle.
    N Engl J Med. 2021;384:286-287.
    >> Share

  96. WALTERS MC
    Induction of Fetal Hemoglobin by Gene Therapy.
    N Engl J Med. 2021;384:284-285.
    >> Share

  97. ESRICK EB, Lehmann LE, Biffi A, Achebe M, et al
    Post-Transcriptional Genetic Silencing of BCL11A to Treat Sickle Cell Disease.
    N Engl J Med. 2021;384:205-215.
    >> Share

  98. FRANGOUL H, Altshuler D, Cappellini MD, Chen YS, et al
    CRISPR-Cas9 Gene Editing for Sickle Cell Disease and beta-Thalassemia.
    N Engl J Med. 2021;384:252-260.
    >> Share

    December 2020
  99. KIRPALANI H, Bell EF, Hintz SR, Tan S, et al
    Higher or Lower Hemoglobin Transfusion Thresholds for Preterm Infants.
    N Engl J Med. 2020;383:2639-2651.
    >> Share

  100. MENSAH F, Pilichowska M
    Hemophagocytosis of Sickle Cells.
    N Engl J Med. 2020;383:2571.
    >> Share

  101. KWAMBAI TK, Dhabangi A, Idro R, Opoka R, et al
    Malaria Chemoprevention in the Postdischarge Management of Severe Anemia.
    N Engl J Med. 2020;383:2242-2254.
    >> Share

    November 2020
  102. MALHOTRA R, Namasivayam M, Ghoshhajra BB, Passeri JJ, et al
    Case 36-2020: A 72-Year-Old Woman with Dark Urine and Weakness.
    N Engl J Med. 2020;383:2066-2076.
    >> Share

  103. POWER-HAYS A, McGann PT
    When Actions Speak Louder Than Words - Racism and Sickle Cell Disease.
    N Engl J Med. 2020;383:1902-1903.
    >> Share


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