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Alzheimer's Disease

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Articles published in
Science
    March 2026
  1. BOLES J, Gate D
    Astrocytes engineered to fight Alzheimer's plaques.
    Science. 2026;391:990-991.
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  2. CHEN Y, Liu Y, Nguyen K, Wu J, et al
    Targeting amyloid-beta pathology by chimeric antigen receptor astrocyte (CAR-A) therapy.
    Science. 2026;391:eads3972.
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    January 2026
  3. PILLER C
    Fake data from trial sites ruin studies, drug firms say.
    Science. 2026;391:112-114.
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    December 2025

  4. Erratum for the Report "Site-specific phosphorylation of tau inhibits amyloid-beta toxicity in Alzheimer's mice" by A. Ittner et al.
    Science. 2025;390:eaee4634.
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    October 2025
  5. DEPP C
    White matters arising: Rethinking Alzheimer's disease through the lens of myelin.
    Science. 2025;390:483.
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  6. DONG G, Ma CC, Mao S, Brown KS, et al
    Diverse somatic genomic alterations in single neurons in chronic traumatic encephalopathy.
    Science. 2025;390:eadu1351.
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  7. CHANG M, Krussel S, Parajuli LK, Kim J, et al
    Intercellular communication in the brain through a dendritic nanotubular network.
    Science. 2025;390:eadr7403.
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    August 2025
  8. XING M, Song W
    Improving Alzheimer's disease immunotherapy.
    Science. 2025;389:571-572.
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  9. PIZZO ME, Plowey ED, Khoury N, Kwan W, et al
    Transferrin receptor-targeted anti-amyloid antibody enhances brain delivery and mitigates ARIA.
    Science. 2025;389:eads3204.
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    July 2025
  10. KEIL SA, Jansson D, Braun M, Iliff JJ, et al
    Glymphatic dysfunction in Alzheimer's disease: A critical appraisal.
    Science. 2025;389:eadv8269.
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  11. THORP HH
    Sluggishness and defensiveness helped enable an executive order on research integrity.
    Science. 2025;389:9.
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    May 2025
  12. TOPOL E
    Predicting and preventing Alzheimer's disease.
    Science. 2025;388:eady3217.
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    April 2025
  13. LESLIE M
    Risky moves.
    Science. 2025;388:244-247.
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    February 2025
  14. ELLIOTT C
    A scientific field, misledDoctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's Charles Piller Atria/One Signal, 2025. 352 pp.
    Science. 2025;387:724.
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    January 2025
  15. ELLIOTT C
    A scientific field, misledDoctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's Charles Piller Atria/One Signal, 2025. 352 pp.
    Science. 2025;387:724.
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    November 2024
  16. LOPEZ-LEE C, Kodama L, Fan L, Zhu D, et al
    Tlr7 drives sex differences in age- and Alzheimer's disease-related demyelination.
    Science. 2024;386:eadk7844.
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  17. COUZIN-FRANKEL J
    Preprint on Alzheimer's drug deaths ignites author dispute.
    Science. 2024;386:717-718.
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  18. COUZIN-FRANKEL J
    Alzheimer's drug approvals create prescribing dilemmas.
    Science. 2024;386:472-473.
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    October 2024
  19. PILLER C
    Firm misled investors on Alzheimer's drug, SEC charges.
    Science. 2024;386:15.
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    September 2024
  20. WALKER LC, Jucker M
    The prion principle and Alzheimer's disease.
    Science. 2024;385:1278-1279.
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  21. KAISER J
    The burden of a gene.
    Science. 2024;385:1154-1157.
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    August 2024
  22. BENN J, Cheng S, Keeling S, Smith AE, et al
    Aggregate-selective removal of pathological tau by clustering-activated degraders.
    Science. 2024;385:1009-1016.
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  23. JOHNSON LA, Macauley SL
    Alzheimer's and metabolism wed with IDO1.
    Science. 2024;385:826-827.
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  24. MINHAS PS, Jones JR, Latif-Hernandez A, Sugiura Y, et al
    Restoring hippocampal glucose metabolism rescues cognition across Alzheimer's disease pathologies.
    Science. 2024;385:eabm6131.
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  25. COUZIN-FRANKEL J
    Hunt for infectious causes of Alzheimer's gains momentum.
    Science. 2024;385:479-480.
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  26. SUN Z, Kwon JS, Ren Y, Chen S, et al
    Modeling late-onset Alzheimer's disease neuropathology via direct neuronal reprogramming.
    Science. 2024;385:adl2992.
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    July 2024
  27. KIPNIS J
    The anatomy of brainwashing.
    Science. 2024;385:368-370.
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    June 2024
  28. PARK J, Wang J, Guan W, Gjesteby LA, et al
    Integrated platform for multiscale molecular imaging and phenotyping of the human brain.
    Science. 2024;384:eadh9979.
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  29. COUZIN-FRANKEL J
    New Alzheimer's drug clears FDA advisory vote despite unknowns.
    Science. 2024;384:1164-1165.
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  30. PILLER C
    Authors move to retract discredited Alzheimer's study.
    Science. 2024;384:1055.
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    May 2024
  31. PRINCEN K, Van Dooren T, van Gorsel M, Louros N, et al
    Pharmacological modulation of septins restores calcium homeostasis and is neuroprotective in models of Alzheimer's disease.
    Science. 2024;384:eadd6260.
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  32. TOPOL EJ
    Medical forecasting.
    Science. 2024;384:eadp7977.
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    March 2024
  33. PILLER C
    'Damning' FDA inspection report undermines Alzheimer's drug.
    Science. 2024;383:1165-1166.
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    December 2023
  34. GOLDE TE, Levey AI
    Immunotherapies for Alzheimer's disease.
    Science. 2023;382:1242-1244.
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    November 2023
  35. PILLER C
    Brain games?
    Science. 2023;382:754-759.
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    October 2023
  36. PILLER C
    Probe of Alzheimer's studies finds 'egregious misconduct'.
    Science. 2023;382:251-252.
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    September 2023
  37. BALUSU S, Horre K, Thrupp N, Craessaerts K, et al
    MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer's disease.
    Science. 2023;381:1176-1182.
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  38. SIRKIS DW, Yokoyama JS
    Role for cell death pathway in Alzheimer's disease.
    Science. 2023;381:1156-1157.
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  39. AGUZZI A, Kampmann M
    Neurodegeneration enters the era of functional genomics.
    Science. 2023;381:eadk5693.
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    August 2023
  40. COUZIN-FRANKEL J
    Side effects loom over Alzheimer's drugs.
    Science. 2023;381:466-467.
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    July 2023
  41. ZHANG ZY, Harischandra DS, Wang R, Ghaisas S, et al
    TRIM11 protects against tauopathies and is down-regulated in Alzheimer's disease.
    Science. 2023;381:eadd6696.
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    May 2023
  42. TRAVIS J
    Latest Alzheimer's antibody is 'not a miracle drug'.
    Science. 2023;380:571.
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    April 2023
  43. PILLER C
    Report on trial death stokes Alzheimer's drug fears.
    Science. 2023;380:122-123.
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  44. COUZIN-FRANKEL J
    Promising Alzheimer's therapies shrink brains.
    Science. 2023;380:19.
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