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Alzheimer's Disease

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Articles published in
Science
    June 2024
  1. PILLER C
    Authors move to retract discredited Alzheimer's study.
    Science. 2024;384:1055.
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    May 2024
  2. PRINCEN K, Van Dooren T, van Gorsel M, Louros N, et al
    Pharmacological modulation of septins restores calcium homeostasis and is neuroprotective in models of Alzheimer's disease.
    Science. 2024;384:eadd6260.
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  3. TOPOL EJ
    Medical forecasting.
    Science. 2024;384:eadp7977.
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    March 2024
  4. PILLER C
    'Damning' FDA inspection report undermines Alzheimer's drug.
    Science. 2024;383:1165-1166.
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    December 2023
  5. GOLDE TE, Levey AI
    Immunotherapies for Alzheimer's disease.
    Science. 2023;382:1242-1244.
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    November 2023
  6. PILLER C
    Brain games?
    Science. 2023;382:754-759.
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    October 2023
  7. PILLER C
    Probe of Alzheimer's studies finds 'egregious misconduct'.
    Science. 2023;382:251-252.
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    September 2023
  8. BALUSU S, Horre K, Thrupp N, Craessaerts K, et al
    MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer's disease.
    Science. 2023;381:1176-1182.
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  9. SIRKIS DW, Yokoyama JS
    Role for cell death pathway in Alzheimer's disease.
    Science. 2023;381:1156-1157.
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  10. AGUZZI A, Kampmann M
    Neurodegeneration enters the era of functional genomics.
    Science. 2023;381:eadk5693.
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    August 2023
  11. COUZIN-FRANKEL J
    Side effects loom over Alzheimer's drugs.
    Science. 2023;381:466-467.
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    July 2023
  12. ZHANG ZY, Harischandra DS, Wang R, Ghaisas S, et al
    TRIM11 protects against tauopathies and is down-regulated in Alzheimer's disease.
    Science. 2023;381:eadd6696.
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    May 2023
  13. TRAVIS J
    Latest Alzheimer's antibody is 'not a miracle drug'.
    Science. 2023;380:571.
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    April 2023
  14. PILLER C
    Report on trial death stokes Alzheimer's drug fears.
    Science. 2023;380:122-123.
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  15. COUZIN-FRANKEL J
    Promising Alzheimer's therapies shrink brains.
    Science. 2023;380:19.
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    January 2023
  16. COUZIN-FRANKEL J
    Alzheimer's drug approval gets a mixed reception.
    Science. 2023;379:126-127.
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    December 2022
  17. COUZIN-FRANKEL J, Piller C
    Alzheimer's drug stirs excitement-and concerns.
    Science. 2022;378:1030-1031.
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    November 2022
  18. PILLER C
    Whistleblower finds possible misconduct in his own papers.
    Science. 2022;378:694-695.
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  19. ENDO F, Kasai A, Soto JS, Yu X, et al
    Molecular basis of astrocyte diversity and morphology across the CNS in health and disease.
    Science. 2022;378:eadc9020.
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    September 2022
  20. HOFFMANN HM
    Boosting cognition with a hormone.
    Science. 2022;377:1042-1043.
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    August 2022
  21. ASHE KH
    Alzheimer's target still viable but untested.
    Science. 2022;377:935.
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  22. SELKOE D, Cummings J
    News story miscasts Alzheimer's science.
    Science. 2022;377:934-935.
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  23. COOPER YA, Teyssier N, Drager NM, Guo Q, et al
    Functional regulatory variants implicate distinct transcriptional networks in dementia.
    Science. 2022;377:eabi8654.
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    July 2022
  24. PILLER C
    Research backing experimental Alzheimer's drug was first target of suspicion.
    Science. 2022;377:363.
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  25. PILLER C
    Research backing experimental Alzheimer's drug was first target of suspicion.
    Science. 2022;377:363.
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  26. PILLER C
    Blots on a field?
    Science. 2022;377:358-363.
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  27. ZHOU X, Sumrow L, Tashiro K, Sutherland L, et al
    Mutations linked to neurological disease enhance self-association of low-complexity protein sequences.
    Science. 2022;377:eabn5582.
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    January 2022
  28. YANG Y, Arseni D, Zhang W, Huang M, et al
    Cryo-EM structures of amyloid-beta 42 filaments from human brains.
    Science. 2022;375:167-172.
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    December 2021
  29. LESLIE M
    Blood condition may guard against Alzheimer's.
    Science. 2021;374:1425.
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    October 2021
  30. SELKOE DJ
    Alzheimer's drugs: Does reducing amyloid work?-Response.
    Science. 2021;374:545-546.
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  31. THAMBISETTY M, Howard R, Glymour MM, Schneider LS, et al
    Alzheimer's drugs: Does reducing amyloid work?
    Science. 2021;374:544-545.
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  32. SPIRES-JONES T
    Toward a holistic model of Alzheimer'sHow Not to Study a Disease: The Story of Alzheimer's Karl Herrup MIT Press, 2021. 272 pp.
    Science. 2021;374:267.
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    August 2021
  33. BLENNOW K
    Phenotyping Alzheimer's disease with blood tests.
    Science. 2021;373:626-628.
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  34. SELKOE DJ
    Treatments for Alzheimer's disease emerge.
    Science. 2021;373:624-626.
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    July 2021
  35. SERVICK K
    Alzheimer's drug approval spotlights blood tests.
    Science. 2021;373:373-374.
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    June 2021
  36. SERVICK K
    Alzheimer's drug approved despite murky results.
    Science. 2021;372:1141.
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    December 2020
  37. NAKAMURA T, Oh CK, Liao L, Zhang X, et al
    Noncanonical transnitrosylation network contributes to synapse loss in Alzheimer's disease.
    Science. 2020 Dec 3. pii: science.aaw0843. doi: 10.1126/science.aaw0843.
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    November 2020
  38. DARWICH NF, Phan JM, Kim B, Suh E, et al
    Autosomal dominant VCP hypomorph mutation impairs disaggregation of PHF-tau.
    Science. 2020;370.
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    October 2020
  39. BARTELS T, De Schepper S, Hong S
    Microglia modulate neurodegeneration in Alzheimer's and Parkinson's diseases.
    Science. 2020;370:66-69.
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  40. SIERKSMA A, Escott-Price V, De Strooper B
    Translating genetic risk of Alzheimer's disease into mechanistic insight and drug targets.
    Science. 2020;370:61-66.
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  41. NEDERGAARD M, Goldman SA
    Glymphatic failure as a final common pathway to dementia.
    Science. 2020;370:50-56.
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    August 2020
  42. SUZUKI K, Elegheert J, Song I, Sasakura H, et al
    A synthetic synaptic organizer protein restores glutamatergic neuronal circuits.
    Science. 2020;369.
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