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Alzheimer's Disease

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Articles published in
Neuroscience
    November 2025
  1. KIM KJ, Villegas AL, Kelley AR, Labut EM, et al
    Sex differences in sleep fragmentation in 5xFAD mice.
    Neuroscience. 2025;589:118-127.
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  2. MELCOP J, Ong JY, Ciaghi S, Keramopoulou M, et al
    Correlation of adult neurogenesis and cognitive performance in touchscreen tasks - assessing the novel small molecule OXS-N1 in mice.
    Neuroscience. 2025;589:322-334.
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  3. ALI S, Kosar S, Sina RM, Sima A, et al
    Serum bile acids and brain hypometabolism in patients across Alzheimer's disease continuum: An [(18)F]FDG-PET study.
    Neuroscience. 2025 Nov 6:S0306-4522(25)01063.
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    October 2025
  4. VANYA, Kumari S, Bagri K, Deshmukh R, et al
    Tangles and Plaques: A deep dive into the pathological hallmarks of Alzheimer's disease.
    Neuroscience. 2025 Oct 30:S0306-4522(25)01048.
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  5. DAS R, Chatterjee A, Roy S
    An interpretable Bayesian framework for Alzheimer's disease prediction with uncertainty quantification.
    Neuroscience. 2025 Oct 15:S0306-4522(25)01013.
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  6. ELAMIN SA, Al Shibli AN, Shaito A, Al-Maadhadi MJMB, et al
    Anti-amyloid monoclonal antibody therapies in Alzheimer's disease - a scoping review.
    Neuroscience. 2025 Oct 10:S0306-4522(25)01003.
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  7. ESCOBAR-LOPEZ M, Salazar-Varas R
    Analysis of EEG coherence according to the onset of Alzheimer's disease.
    Neuroscience. 2025 Oct 10:S0306-4522(25)00979.
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    September 2025
  8. CHAUHAN P, Vadia N, Ballal S, Joshi KK, et al
    Decoding the neuroprotective potential of hesperidin: Insights into Alzheimer's disease.
    Neuroscience. 2025 Sep 20:S0306-4522(25)00954.
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  9. ALSHEHRI ZS
    Integrating artificial intelligence with small molecule therapeutics and precision medicine for neurochemical understanding of Alzheimer's diseases.
    Neuroscience. 2025;586:44-57.
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  10. IQBAL A, Iqbal K, Shah YA, Ullah F, et al
    Multi-filter stacking in inception V3 for enhanced Alzheimer's severity classification.
    Neuroscience. 2025;586:21-31.
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  11. ELENI I, Theofanis V, Zisis B, Eleni S, et al
    A review of the TGF-beta1 pathway in Alzheimer's disease and depression: Possible restoration potential of antidepressants.
    Neuroscience. 2025 Sep 12:S0306-4522(25)00925.
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  12. SHENG J, Wang J, Zhang Q, Huang R, et al
    Cognitive prediction using regional connectivities and network biomarkers in Alzheimer's disease.
    Neuroscience. 2025 Sep 3:S0306-4522(25)00907.
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  13. AKAN T, Akan S, Alp S, Ledbetter CR, et al
    AlzFormer: Video-based space-time attention model for early diagnosis of Alzheimer's disease.
    Neuroscience. 2025 Sep 3:S0306-4522(25)00910.
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  14. LAYAL H, Rajbongshi J, Kumar R, Pandey S, et al
    Hydrogen sulfide in the brain as a silent neuroprotector in Alzheimer's disease.
    Neuroscience. 2025 Sep 2:S0306-4522(25)00905.
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    August 2025
  15. BARROSO DE SOUSA D, Clara Ribeiro Zucato HM, Ribeiro HM, Alexandre-Silva V, et al
    Interplay between depressive symptoms and Alzheimer's disease dementia: unraveling the potential roles of ADAM10 and Negr1.
    Neuroscience. 2025 Aug 12:S0306-4522(25)00848.
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  16. YANG Y, Ji Q, Cao JJ, Zhang YJ, et al
    Overactivation of the inward rectifier K(+) channel 2.1 modulates intrinsic excitability of adult-born granule cells in the male Alzheimer's APP/PS1 mouse model.
    Neuroscience. 2025 Aug 9:S0306-4522(25)00845.
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    July 2025
  17. XU Y, Zhang Z, Peng J, Li X, et al
    Use of magnetic resonance structural imaging to identify disease progression in patients with mild cognitive impairment: A voxel-based morphometry and surface-based morphometry study.
    Neuroscience. 2025;579:382-389.
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  18. NI L, Lin L, Zhao W, Li Y, et al
    Differences in patterns of functional and structural connectivity alterations of hippocampal subregions in patients on the Alzheimer's disease spectrum.
    Neuroscience. 2025 Jul 19:S0306-4522(25)00807.
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  19. AVILA J, Hernandez F, Perry G
    Amyloid and tau pathologies cross-talk to promote Alzheimers disease: novel mechanistic insights.
    Neuroscience. 2025;582:58-62.
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  20. KANG X, Tian J, Shu Q, Cheng T, et al
    Microglia-neuron crosstalk in Alzheimer's disease: an exploration of molecular mechanisms and pathological implications.
    Neuroscience. 2025 Jul 10:S0306-4522(25)00781.
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  21. NASIRI H, Azargoonjahromi A
    Response to "Reevaluating leucine's effects on Alzheimer's disease: evidence of potential benefits overlooked".
    Neuroscience. 2025 Jul 5:S0306-4522(25)00768.
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    June 2025
  22. WANG G, Ma T, Liu R, Gu H, et al
    Comparisons of metabolites and gut microbiota profiles for both young and middle-aged APPSwe/PS1De9 mice.
    Neuroscience. 2025;577:54-63.
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  23. SATHIAN B, Iqbal J, Al Hamad H
    Reevaluating Leucine's effects on Alzheimer's disease: evidence of potential benefits overlooked.
    Neuroscience. 2025;579:121.
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    May 2025
  24. YANG Q, Huang D, Zhang Z, Gao H, et al
    Diabetes affects AD through plasma Abeta40: A Mendelian randomization study.
    Neuroscience. 2025;575:131-139.
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  25. NASIRI H, Azargoonjahromi A, Nouri Z, Azimi SM, et al
    Elevated serum leucine levels are associated with cognitive impairment and reduced gray matter and cerebral volume across the Alzheimer's disease continuum.
    Neuroscience. 2025;577:47-53.
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  26. AATHIRA NS, Kaur A, Kumar A, Dar GM, et al
    The genetic risk factors, molecular pathways, microRNAs, and the gut microbiome in Alzheimer's disease.
    Neuroscience. 2025 May 13:S0306-4522(25)00373.
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  27. GALAL A, Moustafa A, Salama M
    Transforming neurodegenerative disorder care with machine learning: Strategies and applications.
    Neuroscience. 2025;573:272-285.
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  28. MORAIS RF, Pires R, Jesus T, Lemos R, et al
    Cognitive impairment in neurodegenerative diseases: A trans-diagnostic approach using a lesion-symptom mapping analysis.
    Neuroscience. 2025;573:214-227.
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    April 2025
  29. ZHANG R, Sheng J, Zhang Q, Wang J, et al
    A review of multimodal fusion-based deep learning for Alzheimer's disease.
    Neuroscience. 2025;576:80-95.
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  30. JAIN S, Srivastava R
    Enhanced EEG-based Alzheimer's disease detection using synchrosqueezing transform and deep transfer learning.
    Neuroscience. 2025;576:105-117.
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  31. JOLIVALT CG, Calcutt NA, Masliah E
    Corrigendum to "Similar pattern of peripheral neuropathy in mouse models of type 1 diabetes and Alzheimer's disease" [Neuroscience 202 (2012) 405-412].
    Neuroscience. 2025;575:94.
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  32. ROY KK, Mehta DK, Das R
    Reevaluating Alzheimer's disease treatment: Can phytochemicals bridge the therapeutic Gap?
    Neuroscience. 2025;575:1-18.
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  33. KHANDAYATARAY P, Murthy MK
    Exploring the nexus: Sleep disorders, circadian dysregulation, and Alzheimer's disease.
    Neuroscience. 2025;574:21-41.
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  34. KAUR A, Aran KR
    Unraveling the cGAS-STING pathway in Alzheimer's disease: A new Frontier in neuroinflammation and therapeutic strategies.
    Neuroscience. 2025;573:430-441.
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    March 2025
  35. SHAH FA, Qadir H, Khan JZ, Faheem M, et al
    A review: From old drugs to new solutions: The role of repositioning in alzheimer's disease treatment.
    Neuroscience. 2025 Mar 29:S0306-4522(25)00266.
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  36. LAU F, Binacchi R, Brugnara S, Cumplido-Mayoral A, et al
    Using Single-Cell RNA sequencing with Drosophila, Zebrafish, and mouse models for studying Alzheimer's and Parkinson's disease.
    Neuroscience. 2025 Mar 26:S0306-4522(25)00244.
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  37. CHEN J, Xu S, Wang L, Liu X, et al
    Refining the interactions between microglia and astrocytes in Alzheimer's disease pathology.
    Neuroscience. 2025;573:183-197.
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  38. LI Y, Yang C, Liu X, Shu J, et al
    Potential therapeutic targets for Alzheimer's disease: Fibroblast growth factors and their regulation of ferroptosis, pyroptosis and autophagy.
    Neuroscience. 2025;573:42-51.
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  39. YAN X, Wang E, Zhao M, Ma G, et al
    Microbial infection instigates tau-related pathology in Alzheimer's disease via activating neuroimmune cGAS-STING pathway.
    Neuroscience. 2025;572:122-133.
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    February 2025
  40. WU M, Zhang R, Fu P, Mei Y, et al
    Disrupted astrocyte-neuron signaling reshapes brain activity in epilepsy and Alzheimer's disease.
    Neuroscience. 2025;570:132-151.
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  41. KALRA P, Grewal AK, Khan H, Singh TG, et al
    Unscrambling the cellular and molecular threads of Neuroplasticity: Insights into Alzheimer's disease pathogenesis.
    Neuroscience. 2025 Feb 17:S0306-4522(25)00151.
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    January 2025
  42. YU Y, Shen H, Qin Q, Wang J, et al
    The investigation of peripheral inflammatory and oxidative stress biomarkers in dementia with Lewy Bodies, compared with Alzheimer's Disease, and mild cognitive impairment.
    Neuroscience. 2025 Jan 10:S0306-4522(24)00764.
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    December 2024
  43. WANG ZJ, Han WN, Chai SF, Li Y, et al
    Semaglutide promotes the transition of microglia from M1 to M2 type to reduce brain inflammation in APP/PS1/tau mice.
    Neuroscience. 2024;563:222-234.
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  44. WOOD OWG, Yeung JHY, Palpagama TH, Turner C, et al
    Upregulated excitatory amino acid transporter 1 (EAAT1) expression in the human medial temporal lobe in Alzheimer's disease.
    Neuroscience. 2024 Dec 16:S0306-4522(24)00734.
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  45. APARAJITA A, Jain U, Srivastava P
    "Current and emerging drug therapies in Alzheimer's disease: A pathophysiological Perspective".
    Neuroscience. 2024;565:499-518.
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  46. FANG H, Tian H, Liu J, Peng T, et al
    Ginsenoside Rg1 attenuates Abeta(1-42)-induced microglial cell apoptosis and inflammation in Alzheimer's disease via the GATA4/PDE4A/PI3K/AKT axis.
    Neuroscience. 2024;565:377-385.
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  47. LI C, Wang S, Xia Y, Shi F, et al
    Risk factors and predictive models in the progression from MCI to Alzheimer's disease.
    Neuroscience. 2024;565:312-319.
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    November 2024
  48. MOHAMMAD HOSSEINI A, Khaleghzadeh-Ahangar H, Rahimi A
    The immunomodulatory effects of psychedelics in Alzheimer's disease-related dementia.
    Neuroscience. 2024 Nov 25:S0306-4522(24)00651.
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  49. ZHENG Y, Yu X, Li W, Wu F, et al
    HLA is a potent immunoinflammatory target in asymptomatic Alzheimer's disease.
    Neuroscience. 2024 Nov 19:S0306-4522(24)00638.
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  50. CAO W, Zhu B, Liu Z, Jia X, et al
    Comparison of the efficacy of updated drugs for the treatment on the improvement of cognitive function in patients with Alzheimer 's disease: A systematic review and network meta- analysis.
    Neuroscience. 2024 Nov 14:S0306-4522(24)00611.
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  51. KHANDAYATARAY P, Murthy MK
    Dietary interventions in mitigating the impact of environmental pollutants on Alzheimer's disease - A review.
    Neuroscience. 2024 Nov 12:S0306-4522(24)00602.
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  52. YUAN J, Dong X, Zhou S, Nao J, et al
    Pharmacological activities and therapeutic potential of Hyperoside in the treatment of Alzheimer's and Parkinson's diseases: A systemic review.
    Neuroscience. 2024 Nov 1:S0306-4522(24)00565.
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    October 2024
  53. SCARPA JR, Mincer JS
    Chronic pain-induced methylation in the prefrontal cortex targets gene networks associated with cognition and Alzheimer's disease.
    Neuroscience. 2024 Oct 15:S0306-4522(24)00519.
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  54. ZHOU J, Gong L, Liu X, Chen L, et al
    Mendelian randomization in Alzheimer's disease and mild cognitive impairment: Hippocampal volume associations.
    Neuroscience. 2024 Oct 3:S0306-4522(24)00510.
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  55. SINGH R, Joshi A, Koundal M, Sabharwal A, et al
    Proteomic insights into early-stage Alzheimer's disease: Identifying key neuronal proteins impacted by amyloid beta oligomers in an in vitro model.
    Neuroscience. 2024 Oct 1:S0306-4522(24)00503.
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    August 2024
  56. GUTIERREZ RICO E, Joseph P, Noutsos C, Poon K, et al
    Hypothalamic and hippocampal transcriptome changes in App(NL-G-F) mice as a function of metabolic and inflammatory dysfunction.
    Neuroscience. 2024;554:107-117.
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  57. SOHN E, Lim HS, Jin Kim Y, Kim BY, et al
    Exploring the therapeutic potential of Potentilla fragarioides var. major (Rosaceae) extract in Alzheimer's disease using in vitro and in vivo models: a multi-faceted approach.
    Neuroscience. 2024 Aug 21:S0306-4522(24)00427.
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  58. E R SIMMATIS L, Russo EE, Altug Y, Murugathas V, et al
    Towards discovery and implementation of neurophysiologic biomarkers of Alzheimer's disease using entropy methods.
    Neuroscience. 2024 Aug 18:S0306-4522(24)00403.
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  59. CHEN J, Peng G, Sun B
    Alzheimer's disease and sleep disorders: A bidirectional relationship.
    Neuroscience. 2024;557:12-23.
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    July 2024
  60. XIANG LY, Chen XY, Lu LM, Kong MH, et al
    Mechanisms of Neuronal Reactivation in Memory Consolidation: A Perspective from Pathological Conditions.
    Neuroscience. 2024;551:196-204.
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  61. BHATT A, Bhardwaj H, Shrivastava P
    Mesenchymal stem cell therapy for Alzheimer's disease: A novel therapeutic approach for neurodegenerative diseases.
    Neuroscience. 2024 Jul 18:S0306-4522(24)00332.
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    June 2024
  62. AHMAD RATHER M, Khan A, Jahan S, Jamal Siddiqui A, et al
    Influence of Tau on neurotoxicity and cerebral vasculature impairment associated with Alzheimer's disease.
    Neuroscience. 2024 Jun 11:S0306-4522(24)00252.
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    April 2024
  63. DENG J, Liu B, Tao Q, Luo Y, et al
    The co-oligomers of Abeta42 and human islet amyloid polypeptide exacerbate neurotoxicity and Alzheimer-like pathology at cellular level.
    Neuroscience. 2024 Apr 9:S0306-4522(24)00155.
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    March 2024
  64. W G WOOD O, Walby J, Yeung JH, Ke S, et al
    Alzheimer's disease-associated region-specific decrease of vesicular glutamate transporter immunoreactivity inthe medial temporal lobe and superior temporal gyrus.
    Neuroscience. 2024 Mar 27:S0306-4522(24)00140.
    >> Share

  65. MEHMOOD A, Shahid F, Khan R, Ibrahim MM, et al
    Utilizing Siamese 4D-AlzNet and Transfer Learning to Identify Stages of Alzheimer's Disease.
    Neuroscience. 2024 Mar 14:S0306-4522(24)00112.
    >> Share

    February 2024
  66. XU M, Lin R, Wen H, Wang Y, et al
    Electroacupuncture Enhances the Functional Connectivity of Limbic System to Neocortex in the 5xFAD Mouse Model of Alzheimer's Disease.
    Neuroscience. 2024 Feb 27:S0306-4522(24)00090.
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  67. ZHANG H, Yang Y, Zhang J, Huang L, et al
    Oligodendrocytes Play a Critical Role in White Matter Damage of Vascular Dementia.
    Neuroscience. 2024;538:1-10.
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    January 2024
  68. QIAO Y, Liu H, He C, Ma Y, et al
    ApoE Mimic Peptide COG1410 Reduces Abeta Deposition and Improves Cognitive Function by Inducing the Transformation of A1/A2 Reactive Astrocytes and Increasing the BDNF Concentration in Brain of APP/PS1 Double Transgenic Mice.
    Neuroscience. 2024;537:116-125.
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  69. ALIASHRAFI M, Nasehi M, Zarrindast MR, Joghataei MT, et al
    Intracerebroventricular Cutibacterium acnes generates manifestations of Alzheimer's disease-like pathology in the rat hippocampus.
    Neuroscience. 2024 Jan 22:S0306-4522(24)00023.
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    November 2023
  70. WANG Q, Guo S, Hu D, Dong X, et al
    Enhanced GSDME-mediated pyroptosis in Alzheimer's disease.
    Neuroscience. 2023 Nov 7:S0306-4522(23)00491.
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    September 2023
  71. ELDEEN MAKKI B, Rahman S
    Erratum to "Alzheimer's Disease in Diabetic Patients: A Lipidomic Prospect" [Neuroscience 530 (2023) 79-94].
    Neuroscience. 2023 Sep 26:S0306-4522(23)00427.
    >> Share

  72. LIU S, Zheng Y, Li H, Pan M, et al
    Improving Alzheimer Diagnoses with an interpretable Deep Learning Framework: including Neuropsychiatric Symptoms.
    Neuroscience. 2023 Sep 12:S0306-4522(23)00411.
    >> Share

    August 2023
  73. ELDEEN MAKKI B, Rahman S
    Alzheimer's Disease in Diabetic Patients: A Lipidomic Prospect.
    Neuroscience. 2023 Aug 29:S0306-4522(23)00402.
    >> Share

  74. WANG L, Wei Y, Sun Z, Jiang LH, et al
    DpdtpA, A Multi-metal Ion Chelator, Attenuates Tau Phosphorylation and Microglial Inflammatory Response via Regulating the PI3K/AKT/GSK-3beta Signal Pathways.
    Neuroscience. 2023;526:196-203.
    >> Share

  75. LIN LL, Song GJ, Zhang H, Yin Y, et al
    GPR34 knockdown relieves cognitive deficits and suppresses neuroinflammation in Alzheimer's disease via the ERK/NF-kappaB signal.
    Neuroscience. 2023 Aug 7:S0306-4522(23)00342.
    >> Share

  76. YANG P, Liao C, Hu Q, Zhang J, et al
    Benzene, 1,2,4-Trimethoxy-5-(2-Methyl-1-Propen-1-yl) Attenuates D-galactose/AlCl(3)-induced Cognitive Impairment by Inhibiting Inflammation, Apoptosis, and improving Expression of Memory-Related Proteins.
    Neuroscience. 2023;524:242-255.
    >> Share

    June 2023
  77. WANG H, Zhang Z, Sittirattanayeungyong S, Hongpaisan J, et al
    ApoE4-related microvascular disease in the Alzheimer's disease hippocampal CA1 stratum radiatum.
    Neuroscience. 2023 Jun 27:S0306-4522(23)00289.
    >> Share

  78. GUNAWARDENA R, Sarrigiannis PG, Blackburn DJ, He F, et al
    Kernel-based Nonlinear Manifold Learning for EEG-based Functional Connectivity Analysis and Channel Selection with Application to Alzheimer's Disease.
    Neuroscience. 2023 Jun 8:S0306-4522(23)00253.
    >> Share

  79. LI Y, Fan H, Ni M, Zhang W, et al
    Targeting lncRNA NEAT1 hampers Alzheimer's disease progression.
    Neuroscience. 2023 Jun 5:S0306-4522(23)00103.
    >> Share

  80. FROST J, Schmitzer B, Topperwien M, Eckermann M, et al
    3d Virtual Histology Reveals Pathological Alterations of Cerebellar Granule Cells in Multiple Sclerosis.
    Neuroscience. 2023;520:18-38.
    >> Share

    May 2023
  81. MOLINERO N, Anton-Fernandez A, Hernandez F, Avila J, et al
    Gut Microbiota, an Additional Hallmark of Human Aging and Neurodegeneration.
    Neuroscience. 2023;518:141-161.
    >> Share

  82. FOUREST-LIEUVIN A, Vinit A, Blot B, Perrot A, et al
    Controlled Tau Cleavage in Cells Reveals Abnormal Localizations of Tau Fragments.
    Neuroscience. 2023;518:162-177.
    >> Share

  83. GALLO D, Ruiz A, Sanchez-Juan P
    Genetic Architecture of Primary Tauopathies.
    Neuroscience. 2023;518:27-37.
    >> Share

  84. JIMENEZ JS
    Macromolecular Structures and Proteins Interacting with the Microtubule Associated Tau Protein.
    Neuroscience. 2023;518:70-82.
    >> Share

  85. SCHULZ L, Ramirez P, Lemieux A, Gonzalez E, et al
    Tau-Induced Elevation of the Activity-Regulated Cytoskeleton Associated Protein Arc1 Causally Mediates Neurodegeneration in the Adult Drosophila Brain.
    Neuroscience. 2023;518:101-111.
    >> Share

  86. BERROCAL M, Mata AM
    The Plasma Membrane Ca(2+)-ATPase, a Molecular Target for Tau-induced Cytosolic Calcium Dysregulation.
    Neuroscience. 2023;518:112-118.
    >> Share

  87. CAAMANO-MORENO M, Gargini R
    Tauopathies: The Role of Tau in Cellular Crosstalk and Synaptic Dysfunctions.
    Neuroscience. 2023;518:38-53.
    >> Share

  88. ANDRES-BENITO P, Carmona M, Pirla MJ, Torrejon-Escribano B, et al
    Dysregulated Protein Phosphorylation as Main Contributor of Granulovacuolar Degeneration at the First Stages of Neurofibrillary Tangles Pathology.
    Neuroscience. 2023;518:119-140.
    >> Share

  89. CONCEPCION FA, Ekstrom NA, Khan MN, Estes OO, et al
    Progressive Dysregulation of Tau Phosphorylation in an Animal Model of Temporal Lobe Epilepsy.
    Neuroscience. 2023 May 2:S0306-4522(23)00193.
    >> Share

    April 2023
  90. KLEPL D, He F, Wu M, Blackburn DJ, et al
    Cross-Frequency Multilayer Network Analysis with Bispectrum-based Functional Connectivity: A Study of Alzheimer's Disease.
    Neuroscience. 2023 Apr 28:S0306-4522(23)00167.
    >> Share

  91. MURRAY HC, Saar G, Bai L, Bouraoud N, et al
    Progressive Spread of Beta-amyloid Pathology in an Olfactory-driven Amyloid Precursor Protein Mouse Model.
    Neuroscience. 2023;516:113-124.
    >> Share

    March 2023
  92. REN S, Li J, Huang L, Huang Q, et al
    Brain Functional Alterations and Association with Cognition in People with Preclinical Subjective Cognitive Decline and Objective Subtle Cognitive Difficulties.
    Neuroscience. 2023;513:137-144.
    >> Share

    February 2023
  93. PLACHEZ C, Tsytsarev V, Zhao S, Erzurumlu RS, et al
    Amyloid Deposition and Dendritic Complexity of Corticocortical Projection Cells in Five Familial Alzheimer's Disease Mouse.
    Neuroscience. 2023;512:85-98.
    >> Share

    October 2021
  94. VIARD A, Eustache F, Segobin S
    History of Magnetic Resonance Imaging: A Trip Down Memory Lane.
    Neuroscience. 2021;474:3-13.
    >> Share


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