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Articles published in
Neurobiol Dis
    May 2024
  1. XIE B, Yang S, Hao Y, Sun Y, et al
    Impaired olfactory identification in dementia-free individuals is associated with the functional abnormality of the precuneus.
    Neurobiol Dis. 2024;194:106483.
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    April 2024
  2. SCHRAEN-MASCHKE S, Duhamel A, Vidal JS, Ramdane N, et al
    The free plasma amyloid Abeta(1)(-)(42)/Abeta(1)(-)(40) ratio predicts conversion to dementia for subjects with mild cognitive impairment with performance equivalent to that of the total plasma Abeta(1)(-)(42)/Abeta(1)(-)(40) ratio. The BALTAZAR study.
    Neurobiol Dis. 2024;193:106459.
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  3. JIAO LL, Dong HL, Liu MM, Wu PL, et al
    The potential roles of salivary biomarkers in neurodegenerative diseases.
    Neurobiol Dis. 2024;193:106442.
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  4. JADHAV VS, Stair JG, Eck RJ, Smukowski SN, et al
    Transcriptomic evaluation of tau and TDP-43 synergism shows tauopathy predominance and reveals potential modulating targets.
    Neurobiol Dis. 2024;193:106441.
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    March 2024
  5. BONIFAZI G, Luchena C, Gaminde-Blasco A, Ortiz-Sanz C, et al
    A nonlinear meccano for Alzheimer's emergence by amyloid beta-mediated glutamatergic hyperactivity.
    Neurobiol Dis. 2024 Mar 15:106473. doi: 10.1016/j.nbd.2024.106473.
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  6. YAMASHIRO K, Takabayashi K, Kamagata K, Nishimoto Y, et al
    Free water in gray matter linked to gut microbiota changes with decreased butyrate producers in Alzheimer's disease and mild cognitive impairment.
    Neurobiol Dis. 2024 Mar 5:106464. doi: 10.1016/j.nbd.2024.106464.
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  7. ZENG J, Liao Z, Yang H, Wang Q, et al
    T cell infiltration mediates neurodegeneration and cognitive decline in Alzheimer's disease.
    Neurobiol Dis. 2024;193:106461.
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  8. TATO-FERNANDEZ C, Ekblad LL, Pietila E, Saunavaara V, et al
    Cognitively healthy APOE4/4 carriers show white matter impairment associated with serum NfL and amyloid-PET.
    Neurobiol Dis. 2024;192:106439.
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  9. LONG DM, Cravetchi O, Chow ES, Allen C, et al
    The amyloid precursor protein intracellular domain induces sleep disruptions and its nuclear localization fluctuates in circadian pacemaker neurons in Drosophila and mice.
    Neurobiol Dis. 2024;192:106429.
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    February 2024
  10. KATSUMATA Y, Wu X, Aung KZ, Gauthreaux K, et al
    Pathologic correlates of aging-related tau astrogliopathy: ARTAG is associated with LATE-NC and cerebrovascular pathologies, but not with ADNC.
    Neurobiol Dis. 2024;191:106412.
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    January 2024
  11. KOURTI M, Metaxas A
    A systematic review and meta-analysis of tau phosphorylation in mouse models of familial Alzheimer's disease.
    Neurobiol Dis. 2024 Jan 31:106427. doi: 10.1016/j.nbd.2024.106427.
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  12. IVANOVA M, Belaya I, Kucharikova N, de Sousa Maciel I, et al
    Upregulation of Integrin beta-3 in astrocytes upon Alzheimer's disease progression in the 5xFAD mouse model.
    Neurobiol Dis. 2024;191:106410.
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  13. GHARPURE M, Vyavahare S, Ahluwalia P, Gupta SK, et al
    Alterations in Alzheimer's disease microglia transcriptome might be involved in bone pathophysiology.
    Neurobiol Dis. 2024;191:106404.
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  14. PIETILA E, Snellman A, Tuisku J, Helin S, et al
    Midlife insulin resistance, APOE genotype, and change in late-life brain beta-amyloid accumulation - A 5-year follow-up [(11)C]PIB-PET study.
    Neurobiol Dis. 2024;190:106385.
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    December 2023
  15. ZHANG T, Dolga AM, Eisel ULM, Schmidt M, et al
    Novel crosstalk mechanisms between GluA3 and Epac2 in synaptic plasticity and memory in Alzheimer's disease.
    Neurobiol Dis. 2023 Dec 22:106389. doi: 10.1016/j.nbd.2023.106389.
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  16. KOPCANOVA M, Tait L, Donoghue T, Stothart G, et al
    Resting-state EEG signatures of Alzheimer's disease are driven by periodic but not aperiodic changes.
    Neurobiol Dis. 2023 Dec 17:106380. doi: 10.1016/j.nbd.2023.106380.
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  17. LIANG K, Li X, Guo Q, Ma J, et al
    Structural changes in the retina and serum HMGB1 levels are associated with decreased cognitive function in patients with Parkinson's disease.
    Neurobiol Dis. 2023;190:106379.
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  18. HANERT A, Schonfeld R, Weber FD, Nowak A, et al
    Reduced overnight memory consolidation and associated alterations in sleep spindles and slow oscillations in early Alzheimer's disease.
    Neurobiol Dis. 2023 Dec 14:106378. doi: 10.1016/j.nbd.2023.106378.
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  19. TIMSINA J, Ali M, Do A, Wang L, et al
    Harmonization of CSF and imaging biomarkers in Alzheimer's disease: Need and practical applications for genetics studies and preclinical classification.
    Neurobiol Dis. 2023;190:106373.
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    November 2023
  20. NAJAR J, Thorvaldsson V, Kern S, Skoog J, et al
    Polygenic risk scores for Alzheimer's disease in relation to cognitive change: A representative sample from the general population followed over 16 years.
    Neurobiol Dis. 2023;189:106357.
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  21. WOJDALA AL, Bellomo G, Gaetani L, Toja A, et al
    Trajectories of CSF and plasma biomarkers across Alzheimer's disease continuum: disease staging by NF-L, p-tau181, and GFAP.
    Neurobiol Dis. 2023;189:106356.
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  22. LI K, Luo X, Zeng Q, Liu X, et al
    Gray matter structural covariance networks patterns associated with autopsy-confirmed LATE-NC compared to Alzheimer's disease pathology.
    Neurobiol Dis. 2023;189:106354.
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    October 2023
  23. GAUTIER MK, Kelley CM, Lee SH, Alldred MJ, et al
    Maternal choline supplementation protects against age-associated cholinergic and GABAergic basal forebrain neuron degeneration in the Ts65Dn mouse model of down syndrome and Alzheimer's disease.
    Neurobiol Dis. 2023 Oct 25:106332. doi: 10.1016/j.nbd.2023.106332.
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  24. HIGGINBOTHAM L, Carter EK, Dammer EB, Haque RU, et al
    Unbiased classification of the elderly human brain proteome resolves distinct clinical and pathophysiological subtypes of cognitive impairment.
    Neurobiol Dis. 2023;186:106286.
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    September 2023
  25. BOTELLO-MARABOTTO M, Martinez-Bisbal MC, Calero M, Bernardos A, et al
    Non-invasive biomarkers for mild cognitive impairment and Alzheimer's disease.
    Neurobiol Dis. 2023 Sep 26:106312. doi: 10.1016/j.nbd.2023.106312.
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  26. CAO E, Ma D, Nayak S, Duong TQ, et al
    Deep learning combining FDG-PET and neurocognitive data accurately predicts MCI conversion to Alzheimer's dementia 3-year post MCI diagnosis.
    Neurobiol Dis. 2023 Sep 26:106310. doi: 10.1016/j.nbd.2023.106310.
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  27. ISRAEL LL, Braubach O, Shatalova ES, Chepurna O, et al
    Exposure to environmental airborne particulate matter caused wide-ranged transcriptional changes and accelerated Alzheimer's-related pathology: A mouse study.
    Neurobiol Dis. 2023;187:106307.
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  28. MEDINA-VERA D, Zambrana-Infantes EN, Lopez-Gambero AJ, Verheul-Campos J, et al
    Transcending the amyloid-beta dominance paradigm in Alzheimer's disease: An exploration of behavioural, metabolic, and gut microbiota phenotypes in 5xFAD mice.
    Neurobiol Dis. 2023 Sep 15:106295. doi: 10.1016/j.nbd.2023.106295.
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  29. LISGARAS CP, Scharfman HE
    Interictal spikes in Alzheimer's disease: Preclinical evidence for dominance of the dentate gyrus and cholinergic control by medial septum.
    Neurobiol Dis. 2023 Sep 13:106294. doi: 10.1016/j.nbd.2023.106294.
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  30. LEITAO ADG, Ahammad RU, Spencer B, Wu C, et al
    Novel systemic delivery of a peptide-conjugated antisense oligonucleotide to reduce alpha-synuclein in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2023;186:106285.
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  31. SIGNAL B, Perez Suarez TG, Taberlay PC, Woodhouse A, et al
    Cellular specificity is key to deciphering epigenetic changes underlying Alzheimer's disease.
    Neurobiol Dis. 2023;186:106284.
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  32. MEEHAN CE, Schantell M, Springer SD, Wiesman AI, et al
    Movement-related beta and gamma oscillations indicate parallels and disparities between Alzheimer's disease and HIV-associated neurocognitive disorder.
    Neurobiol Dis. 2023;186:106283.
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    August 2023
  33. GIUFFRE GM, Quaranta D, Costantini EM, Citro S, et al
    Cerebrospinal fluid neurofilament light chain and total-tau as biomarkers of neurodegeneration in Alzheimer's disease and frontotemporal dementia.
    Neurobiol Dis. 2023 Aug 29:106267. doi: 10.1016/j.nbd.2023.106267.
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  34. DAS M, Mao W, Voskobiynyk Y, Necula D, et al
    Alzheimer risk-increasing TREM2 variant causes aberrant cortical synapse density and promotes network hyperexcitability in mouse models.
    Neurobiol Dis. 2023 Aug 15:106263. doi: 10.1016/j.nbd.2023.106263.
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  35. ARMSTRONG MJ, Jin Y, Vattathil SM, Huang Y, et al
    Role of TET1-mediated epigenetic modulation in Alzheimer's disease.
    Neurobiol Dis. 2023;185:106257.
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  36. EMMERSON JT, Do Carmo S, Liu Y, Shalhoub A, et al
    Progressive human-like tauopathy with downstream neurodegeneration and neurovascular compromise in a transgenic rat model.
    Neurobiol Dis. 2023;184:106227.
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  37. DUMONT M, Agostinis A, Singh K, Swan E, et al
    Sex representation in neurodegenerative and psychiatric disorders' preclinical and clinical studies.
    Neurobiol Dis. 2023;184:106214.
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    July 2023
  38. TROJAN E, Curzytek K, Cieslik P, Wieronska JM, et al
    Prenatal stress aggravates age-dependent cognitive decline, insulin signaling dysfunction, and the pro-inflammatory response in the APP(NL-F/NL-F) mouse model of Alzheimer's disease.
    Neurobiol Dis. 2023 Jul 6:106219. doi: 10.1016/j.nbd.2023.106219.
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  39. LEGAZ A, Prado P, Moguilner S, Baez S, et al
    Social and non-social working memory in neurodegeneration.
    Neurobiol Dis. 2023;183:106171.
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    June 2023
  40. MOWRY FE, Espejo-Porras F, Shijie J, Quadri Z, et al
    Chronic nSMase inhibition suppresses neuronal exosome spreading and sex-specifically attenuates amyloid pathology in APP knock-in Alzheimer's disease mice.
    Neurobiol Dis. 2023 Jun 24:106213. doi: 10.1016/j.nbd.2023.106213.
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  41. SUN Y, Bae YE, Zhu J, Zhang Z, et al
    A splicing transcriptome-wide association study identifies novel altered splicing for Alzheimer's disease susceptibility.
    Neurobiol Dis. 2023 Jun 22:106209. doi: 10.1016/j.nbd.2023.106209.
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  42. DI MAIO A, Nuzzo T, Gilio L, Serra M, et al
    Homeostasis of serine enantiomers is disrupted in the post-mortem caudate putamen and cerebrospinal fluid of living Parkinson's disease patients.
    Neurobiol Dis. 2023 Jun 17:106203. doi: 10.1016/j.nbd.2023.106203.
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  43. BRADY ES, Griffiths J, Andrianova L, Bielska MH, et al
    Alterations to parvalbumin-expressing interneuron function and associated network oscillations in the hippocampal - medial prefrontal cortex circuit during natural sleep in App(NL-G-F/NL-G-F) mice.
    Neurobiol Dis. 2023;182:106151.
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  44. FRANKLIN ZJ, Croce L, Dekeryte R, Delibegovic M, et al
    BACE cleavage of APP does not drive the diabetic phenotype of PLB4 mice.
    Neurobiol Dis. 2023;182:106142.
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  45. ZOREC R, Vardjan N
    Adrenergic regulation of astroglial aerobic glycolysis and lipid metabolism: Towards a noradrenergic hypothesis of neurodegeneration.
    Neurobiol Dis. 2023;182:106132.
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  46. LUTSHUMBA J, Wilcock D, Monson NL, Stowe AM, et al
    Sex-based differences in effector cells of the adaptive immune system during Alzheimer's disease and related dementias.
    Neurobiol Dis. 2023 Jun 15:106202. doi: 10.1016/j.nbd.2023.106202.
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  47. PATEL PJ, Ren Y, Yan Z
    Epigenomic analysis of Alzheimer's disease brains reveals diminished CTCF binding on genes involved in synaptic organization.
    Neurobiol Dis. 2023 Jun 9:106192. doi: 10.1016/j.nbd.2023.106192.
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  48. FOMINYKH V, Shadrin AA, Jaholkowski PP, Bahrami S, et al
    Shared genetic loci between Alzheimer's disease and multiple sclerosis: Crossroads between neurodegeneration and immune system.
    Neurobiol Dis. 2023 Jun 5:106174. doi: 10.1016/j.nbd.2023.106174.
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  49. DE FLORES R, Demeilliez-Servouin S, Kuhn E, Chauveau L, et al
    Respective influence of beta-amyloid and APOE epsilon4 genotype on medial temporal lobe subregions in cognitively unimpaired older adults.
    Neurobiol Dis. 2023;181:106127.
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  50. DUWAT C, Leal P, Vautheny A, Auregan G, et al
    Development of an AAV-based model of tauopathy targeting retinal ganglion cells and the mouse visual pathway to study the role of microglia in Tau pathology.
    Neurobiol Dis. 2023;181:106116.
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  51. PEDERSEN TJ, Keil SA, Han W, Wang MX, et al
    The effect of aquaporin-4 mis-localization on Abeta deposition in mice.
    Neurobiol Dis. 2023;181:106100.
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    May 2023
  52. SNELLMAN A, Ekblad LL, Ashton NJ, Karikari TK, et al
    Head-to-head comparison of plasma p-tau181, p-tau231 and glial fibrillary acidic protein in clinically unimpaired elderly with three levels of APOE4-related risk for Alzheimer's disease.
    Neurobiol Dis. 2023 May 31:106175. doi: 10.1016/j.nbd.2023.106175.
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  53. MUSAEUS CS, Frederiksen KS, Andersen BB, Hogh P, et al
    Detection of subclinical epileptiform discharges in Alzheimer's disease using long-term outpatient EEG monitoring.
    Neurobiol Dis. 2023 May 15:106149. doi: 10.1016/j.nbd.2023.106149.
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  54. MABROUK R, Miettinen PO, Tanila H
    Most dystrophic neurites in the common 5xFAD Alzheimer mouse model originate from axon terminals.
    Neurobiol Dis. 2023;182:106150.
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  55. CHEN Z, Reynolds RH, Pardinas AF, Gagliano Taliun SA, et al
    The contribution of Neanderthal introgression and natural selection to neurodegenerative diseases.
    Neurobiol Dis. 2023;180:106082.
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  56. VARBANOV H, Jia S, Kochlamazashvili G, Bhattacharya S, et al
    Rescue of synaptic and cognitive functions in polysialic acid-deficient mice and dementia models by short polysialic acid fragments.
    Neurobiol Dis. 2023;180:106079.
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    April 2023
  57. WITTRAHM R, Takalo M, Kuulasmaa T, Makinen PM, et al
    Protective Alzheimer's disease-associated APP A673T variant predominantly decreases sAPPbeta levels in cerebrospinal fluid and 2D/3D cell culture models.
    Neurobiol Dis. 2023;182:106140.
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  58. SHIN YJ, Evitts KM, Jin S, Howard C, et al
    Amyloid beta peptides (Abeta) from Alzheimer's disease neuronal secretome induce endothelial activation in a human cerebral microvessel model.
    Neurobiol Dis. 2023 Apr 14:106125. doi: 10.1016/j.nbd.2023.106125.
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  59. LI T, Li D, Wei Q, Shi M, et al
    Dissecting the neurovascular unit in physiology and Alzheimer's disease: Functions, imaging tools and genetic mouse models.
    Neurobiol Dis. 2023 Apr 4:106114. doi: 10.1016/j.nbd.2023.106114.
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  60. GRECO GA, Rock M, Amontree M, Lanfranco MF, et al
    CCR5 deficiency normalizes TIMP levels, working memory, and gamma oscillation power in APOE4 targeted replacement mice.
    Neurobiol Dis. 2023;179:106057.
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  61. PRADO P, Moguilner S, Mejia JA, Sainz-Ballesteros A, et al
    Source space connectomics of neurodegeneration: One-metric approach does not fit all.
    Neurobiol Dis. 2023;179:106047.
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  62. AFROZ T, Chevalier E, Audrain M, Dumayne C, et al
    Immunotherapy targeting the C-terminal domain of TDP-43 decreases neuropathology and confers neuroprotection in mouse models of ALS/FTD.
    Neurobiol Dis. 2023;179:106050.
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    March 2023
  63. RIZZELLO E, Pimpinella D, Pignataro A, Titta G, et al
    Lamotrigine rescues neuronal alterations and prevents seizure-induced memory decline in an Alzheimer's disease mouse model.
    Neurobiol Dis. 2023 Mar 29:106106. doi: 10.1016/j.nbd.2023.106106.
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  64. TEIPEL S, Grothe MJ
    MRI-based basal forebrain atrophy and volumetric signatures associated with limbic TDP-43 compared to Alzheimer's disease pathology.
    Neurobiol Dis. 2023;180:106070.
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  65. PARKA A, Degel C, Dreyer J, Richter U, et al
    Early impairments of visually-driven neuronal ensemble dynamics in the rTg4510 tauopathy mouse model.
    Neurobiol Dis. 2023;178:106012.
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  66. CORSI GI, Gadekar VP, Haukedal H, Doncheva NT, et al
    The transcriptomic landscape of neurons carrying PSEN1 mutations reveals changes in extracellular matrix components and non-coding gene expression.
    Neurobiol Dis. 2023;178:105980.
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    February 2023
  67. TOHUMEKEN S, Deme P, Yoo SW, Gupta S, et al
    Neuronal deletion of nSMase2 reduces the production of Abeta and directly protects neurons.
    Neurobiol Dis. 2023;177:105987.
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  68. BAH TM, Siler DA, Ibrahim AH, Cetas JS, et al
    Fluid dynamics in aging-related dementias.
    Neurobiol Dis. 2023;177:105986.
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  69. REN P, Ding W, Li S, Liu G, et al
    Regional transcriptional vulnerability to basal forebrain functional dysconnectivity in mild cognitive impairment patients.
    Neurobiol Dis. 2023;177:105983.
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    January 2023
  70. AINANI H, Bouchmaa N, Mrid RB, El Fatimy R, et al
    Liquid-liquid phase separation of protein tau: An emerging process in Alzheimer's disease pathogenesis.
    Neurobiol Dis. 2023 Jan 23:106011. doi: 10.1016/j.nbd.2023.106011.
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  71. SAUNDERS T, Gunn C, Blennow K, Kvartsberg H, et al
    Neurogranin in Alzheimer's disease and ageing: A human post-mortem study.
    Neurobiol Dis. 2023 Jan 6:105991. doi: 10.1016/j.nbd.2023.105991.
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  72. GOTZE K, Vrillon A, Bouaziz-Amar E, Mouton-Liger F, et al
    Plasma neurofilament light chain in memory clinic practice: Evidence from a real-life study.
    Neurobiol Dis. 2023;176:105937.
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    December 2022
  73. GIRONDA SC, Day SM, Clarke CW, Snipes JA, et al
    Ethanol exposure alters Alzheimer's-related pathology, behavior, and metabolism in APP/PS1 mice.
    Neurobiol Dis. 2022 Dec 16:105967. doi: 10.1016/j.nbd.2022.105967.
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  74. ZHANG H, Chen L, Johnston KG, Crapser J, et al
    Degenerate mapping of environmental location presages deficits in object-location encoding and memory in the 5xFAD mouse model for Alzheimer's disease.
    Neurobiol Dis. 2022;176:105939.
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  75. HERZOG R, Rosas FE, Whelan R, Fittipaldi S, et al
    Genuine high-order interactions in brain networks and neurodegeneration.
    Neurobiol Dis. 2022;175:105918.
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  76. GALLWITZ L, Schmidt L, Marques ARA, Tholey A, et al
    Cathepsin D: Analysis of its potential role as an amyloid beta degrading protease.
    Neurobiol Dis. 2022;175:105919.
    >> Share

  77. NG CAS, Biran LP, Galvano E, Mandelblatt J, et al
    Chemotherapy promotes astrocytic response to Abeta deposition, but not Abeta levels, in a mouse model of amyloid and APOE.
    Neurobiol Dis. 2022;175:105915.
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    November 2022
  78. FELSKY D, Santa-Maria I, Cosacak MI, French L, et al
    The Caribbean-Hispanic Alzheimer's disease brain transcriptome reveals ancestry-specific disease mechanisms.
    Neurobiol Dis. 2022 Nov 30:105938. doi: 10.1016/j.nbd.2022.105938.
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  79. SARKAR S
    Microglial ion channels: Key players in non-cell autonomous neurodegeneration.
    Neurobiol Dis. 2022;174:105861.
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    October 2022
  80. LIN L, Petralia RS, Holtzclaw L, Wang YX, et al
    Alzheimer's disease/dementia-associated brain pathology in aging DPP6-KO mice.
    Neurobiol Dis. 2022 Oct 6:105887. doi: 10.1016/j.nbd.2022.105887.
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  81. QUINN JF, Kelly MJ, Harris CJ, Hack W, et al
    The novel estrogen modulator STX attenuates Amyloid-beta neurotoxicity in the 5XFAD mouse model of Alzheimer's disease.
    Neurobiol Dis. 2022 Oct 6:105888. doi: 10.1016/j.nbd.2022.105888.
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  82. JIN SX, Liu L, Li S, Meunier AL, et al
    Abeta oligomers from human brain impair mossy fiber LTP in CA3 of hippocampus, but activating cAMP-PKA and cGMP-PKG prevents this.
    Neurobiol Dis. 2022;172:105816.
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    September 2022
  83. KATSUMATA Y, Shade LM, Hohman TJ, Schneider JA, et al
    Multiple gene variants linked to Alzheimer's-type clinical dementia via GWAS are also associated with non-Alzheimer's neuropathologic entities.
    Neurobiol Dis. 2022 Sep 30:105880. doi: 10.1016/j.nbd.2022.105880.
    >> Share

  84. KHANDELWAL M, Manglani K, Upadhyay P, Azad M, et al
    AdipoRon induces AMPK activation and ameliorates Alzheimer's like pathologies and associated cognitive impairment in APP/PS1 mice.
    Neurobiol Dis. 2022;174:105876.
    >> Share

  85. DE FISENNE MA, Yilmaz Z, De Decker R, Suain V, et al
    Alzheimer PHF-tau aggregates do not spread tau pathology to the brain via the Retino-tectal projection after intraocular injection in mouse models.
    Neurobiol Dis. 2022 Sep 22:105875. doi: 10.1016/j.nbd.2022.105875.
    >> Share

  86. LI Y, Xia M, Meng S, Wu D, et al
    MicroRNA-29c-3p in dual-labeled exosome is a potential diagnostic marker of subjective cognitive decline.
    Neurobiol Dis. 2022;171:105800.
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  87. YANG Z, Wang J, Chen J, Luo M, et al
    High-resolution NMR metabolomics of patients with subjective cognitive decline plus: Perturbations in the metabolism of glucose and branched-chain amino acids.
    Neurobiol Dis. 2022;171:105782.
    >> Share

  88. CESPEDES M, Jacobs KR, Maruff P, Rembach A, et al
    Systemic perturbations of the kynurenine pathway precede progression to dementia independently of amyloid-beta.
    Neurobiol Dis. 2022;171:105783.
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  89. BLESSING EM, Parekh A, Betensky RA, Babb J, et al
    Association between lower body temperature and increased tau pathology in cognitively normal older adults.
    Neurobiol Dis. 2022;171:105748.
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    August 2022
  90. GU Z, Cao H, Zuo C, Huang Y, et al
    TFEB in Alzheimer's disease: From molecular mechanisms to therapeutic implications.
    Neurobiol Dis. 2022 Aug 25:105855. doi: 10.1016/j.nbd.2022.105855.
    >> Share

  91. MEHTA NH, Suss RA, Dyke JP, Theise ND, et al
    Quantifying cerebrospinal fluid dynamics: A review of human neuroimaging contributions to CSF physiology and neurodegenerative disease.
    Neurobiol Dis. 2022;170:105776.
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  92. WILLIAMS ET, Chen X, Otero PA, Moore DJ, et al
    Understanding the contributions of VPS35 and the retromer in neurodegenerative disease.
    Neurobiol Dis. 2022;170:105768.
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    July 2022
  93. MARTINEZ-DRUDIS L, Sheta R, Pellegrinato R, Loukili S, et al
    Inhibition of PLK2 activity affects APP and tau pathology and improves synaptic content in a sex-dependent manner in a 3xTg mouse model of Alzheimer's disease.
    Neurobiol Dis. 2022;172:105833.
    >> Share

  94. ZHANG Y, Gao H, Zheng W, Xu H, et al
    Current understanding of the interactions between metal ions and Apolipoprotein E in Alzheimer's disease.
    Neurobiol Dis. 2022;172:105824.
    >> Share

  95. QIAO Y, Gast G, Su X, Saito T, et al
    Hippocampal neural circuit connectivity alterations in an Alzheimer's disease mouse model revealed by monosynaptic rabies virus tracing.
    Neurobiol Dis. 2022 Jul 14:105820. doi: 10.1016/j.nbd.2022.105820.
    >> Share

  96. NORAMBUENA A, Sun X, Wallrabe H, Cao R, et al
    SOD1 mediates lysosome-to-mitochondria communication and its dysregulation by amyloid-beta oligomers.
    Neurobiol Dis. 2022;169:105737.
    >> Share

    June 2022
  97. RAMAMOORTHY K, Yoshimura R, Al-Juburi S, Anandam KY, et al
    Alzheimer's disease is associated with disruption in thiamin transport physiology: A potential role for neuroinflammation.
    Neurobiol Dis. 2022 Jun 21:105799. doi: 10.1016/j.nbd.2022.105799.
    >> Share

  98. JOHNSON AC, Uhlig F, Einwag Z, Cataldo N, et al
    The neuroendocrine stress response impairs hippocampal vascular function and memory in male and female rats.
    Neurobiol Dis. 2022;168:105717.
    >> Share

  99. AMIN J, Erskine D, Donaghy PC, Surendranathan A, et al
    Inflammation in dementia with Lewy bodies.
    Neurobiol Dis. 2022;168:105698.
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  100. KORF JM, Ganesh BP, McCullough LD
    Gut dysbiosis and age-related neurological diseases in females.
    Neurobiol Dis. 2022;168:105695.
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  101. AHMED MM, Wang AC, Elos M, Chial HJ, et al
    The innate immune system stimulating cytokine GM-CSF improves learning/memory and interneuron and astrocyte brain pathology in Dp16 Down syndrome mice and improves learning/memory in wild-type mice.
    Neurobiol Dis. 2022;168:105694.
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  102. TROUTWINE BR, Strope TA, Franczak E, Lysaker CR, et al
    Mitochondrial function and Abeta in Alzheimer's disease postmortem brain.
    Neurobiol Dis. 2022 Jun 3:105781. doi: 10.1016/j.nbd.2022.105781.
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    May 2022
  103. ZENG Q, Li K, Luo X, Wang S, et al
    The association of enlarged perivascular space with microglia-related inflammation and Alzheimer's pathology in cognitively normal elderly.
    Neurobiol Dis. 2022 May 13:105755. doi: 10.1016/j.nbd.2022.105755.
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  104. LAMPINEN R, Belaya I, Saveleva L, Liddell JR, et al
    Neuron-astrocyte transmitophagy is altered in Alzheimer's disease.
    Neurobiol Dis. 2022;170:105753.
    >> Share

  105. BUHL E, Kim YA, Parsons T, Zhu B, et al
    Effects of Eph/ephrin signalling and human Alzheimer's disease-associated EphA1 on Drosophila behaviour and neurophysiology.
    Neurobiol Dis. 2022 May 12:105752. doi: 10.1016/j.nbd.2022.105752.
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  106. MEEKER KL, Butt OH, Gordon BA, Fagan AM, et al
    Cerebrospinal fluid neurofilament light chain is a marker of aging and white matter damage.
    Neurobiol Dis. 2022;166:105662.
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    April 2022
  107. PURIS E, Auriola S, Petralla S, Hartman R, et al
    Altered protein expression of membrane transporters in isolated cerebral microvessels and brain cortex of a rat Alzheimer's disease model.
    Neurobiol Dis. 2022 Apr 23:105741. doi: 10.1016/j.nbd.2022.105741.
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  108. FILIPELLO F, Goldsbury C, You SF, Locca A, et al
    Soluble TREM2: Innocent bystander or active player in neurological diseases?
    Neurobiol Dis. 2022;165:105630.
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    March 2022
  109. STRAIN JF, Barthelemy N, Horie K, Gordon BA, et al
    CSF Tau phosphorylation at Thr205 is associated with loss of white matter integrity in autosomal dominant Alzheimer's disease.
    Neurobiol Dis. 2022 Mar 28:105714. doi: 10.1016/j.nbd.2022.105714.
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  110. KENKHUIS B, Somarakis A, Kleindouwel LRT, van Roon-Mom WMC, et al
    Co-expression patterns of microglia markers Iba1, TMEM119 and P2RY12 in Alzheimer's disease.
    Neurobiol Dis. 2022;167:105684.
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  111. MOON HJ, Haroutunian V, Zhao L
    Human apolipoprotein E isoforms are differentially sialylated and the sialic acid moiety in ApoE2 attenuates ApoE2-Abeta interaction and Abeta fibrillation.
    Neurobiol Dis. 2022;164:105631.
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    February 2022
  112. GALEA E, Weinstock LD, Larramona-Arcas R, Pybus AF, et al
    Multi-transcriptomic analysis points to early organelle dysfunction in human astrocytes in Alzheimer's disease.
    Neurobiol Dis. 2022 Feb 7:105655. doi: 10.1016/j.nbd.2022.105655.
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    December 2021
  113. SZABO MP, Mishra S, Knupp A, Young JE, et al
    The role of Alzheimer's disease risk genes in endolysosomal pathways.
    Neurobiol Dis. 2021;162:105576.
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  114. STEPANCHUK AA, Barber PA, Lashley T, Joseph JT, et al
    Quantitative detection of grey and white matter amyloid pathology using a combination of K114 and CRANAD-3 fluorescence.
    Neurobiol Dis. 2021;161:105540.
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  115. LIMORENKO G, Lashuel HA
    To target Tau pathologies, we must embrace and reconstruct their complexities.
    Neurobiol Dis. 2021;161:105536.
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    November 2021
  116. LIN X, Chen L, Baglietto-Vargas D, Kamalipour P, et al
    Spatial coding defects of hippocampal neural ensemble calcium activities in the triple-transgenic Alzheimer's disease mouse model.
    Neurobiol Dis. 2021;162:105562.
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  117. GONZALEZ S, McHugh TLM, Yang T, Syriani W, et al
    Small molecule modulation of TrkB and TrkC neurotrophin receptors prevents cholinergic neuron atrophy in an Alzheimer's disease mouse model at an advanced pathological stage.
    Neurobiol Dis. 2021 Nov 24:105563. doi: 10.1016/j.nbd.2021.105563.
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  118. GURDON B, Kaczorowksi C
    Pursuit of precision medicine: Systems biology approaches in Alzheimer's disease mouse models.
    Neurobiol Dis. 2021;161:105558.
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  119. BIYONG ESSI F, Cyntia T, Manon L, Vicky C, et al
    Role of Retinoid X Receptors (RXRs) and dietary vitamin A in Alzheimer's disease: Evidence from clinicopathological and preclinical studies.
    Neurobiol Dis. 2021 Nov 1:105542. doi: 10.1016/j.nbd.2021.105542.
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  120. FERRER-RAVENTOS P, Beyer K
    Alternative platelet activation pathways and their role in neurodegenerative diseases.
    Neurobiol Dis. 2021;159:105512.
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  121. YANGUAS-CASAS N, Torres C, Crespo-Castrillo A, Diaz-Pacheco S, et al
    High-fat diet alters stress behavior, inflammatory parameters and gut microbiota in Tg APP mice in a sex-specific manner.
    Neurobiol Dis. 2021;159:105495.
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  122. LAROCCA TJ, Cavalier AN, Roberts CM, Lemieux MR, et al
    Amyloid beta acts synergistically as a pro-inflammatory cytokine.
    Neurobiol Dis. 2021;159:105493.
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    October 2021
  123. MIYOSHI E, Morabito S, Swarup V
    Systems biology approaches to unravel the molecular and genetic architecture of Alzheimer's disease and related tauopathies.
    Neurobiol Dis. 2021;160:105530.
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    September 2021
  124. OCHIAI T, Sano T, Nagayama T, Kubota N, et al
    Differential involvement of insulin receptor substrate (IRS)-1 and IRS-2 in brain insulin signaling is associated with the effects on amyloid pathology in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2021 Sep 16:105510. doi: 10.1016/j.nbd.2021.105510.
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  125. GRODSTEIN F, Lemos B, Yu L, Klein HU, et al
    The association of epigenetic clocks in brain tissue with brain pathologies and common aging phenotypes.
    Neurobiol Dis. 2021;157:105428.
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    August 2021
  126. FITZ NF, Wang J, Kamboh MI, Koldamova R, et al
    Small nucleolar RNAs in plasma extracellular vesicles and their discriminatory power as diagnostic biomarkers of Alzheimer's disease.
    Neurobiol Dis. 2021 Aug 16:105481. doi: 10.1016/j.nbd.2021.105481.
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  127. WANG X, Zhou X, Uberseder B, Lee J, et al
    Isoform-specific dysregulation of AMP-activated protein kinase signaling in a non-human primate model of Alzheimer's disease.
    Neurobiol Dis. 2021;158:105463.
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  128. HE Q, Jiang L, Zhang Y, Yang H, et al
    Anti-LINGO-1 antibody ameliorates cognitive impairment, promotes adult hippocampal neurogenesis, and increases the abundance of CB1R-rich CCK-GABAergic interneurons in AD mice.
    Neurobiol Dis. 2021;156:105406.
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    July 2021
  129. FUSILIER AR, Davis JA, Paul JR, Yates SD, et al
    Dysregulated clock gene expression and abnormal diurnal regulation of hippocampal inhibitory transmission and spatial memory in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2021 Jul 29:105454. doi: 10.1016/j.nbd.2021.105454.
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    June 2021
  130. PAPPOLLA MA, Perry G, Fang X, Zagorski M, et al
    Indoles as essential mediators in the gut-brain axis. Their role in Alzheimer's disease.
    Neurobiol Dis. 2021;156:105403.
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    May 2021
  131. ZHANG L, Qin Z, Sharmin F, Lin W, et al
    Tyrosine phosphatase PTP1B impairs presynaptic NMDA receptor-mediated plasticity in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2021 May 24:105402. doi: 10.1016/j.nbd.2021.105402.
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    April 2021
  132. MARQUEZ A, Guernsey LS, Frizzi KE, Cundiff M, et al
    Tau associated peripheral and central neurodegeneration: Identification of an early imaging marker for tauopathy.
    Neurobiol Dis. 2021;151:105273.
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  133. TOZZI F, Rutigliano G, Borso M, Falcicchia C, et al
    T1AM-TAAR1 signalling protects against OGD-induced synaptic dysfunction in the entorhinal cortex.
    Neurobiol Dis. 2021;151:105271.
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    March 2021
  134. JIANG N, Cupolillo D, Grosjean N, Muller E, et al
    Impaired plasticity of intrinsic excitability in the dentate gyrus alters spike transfer in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2021 Mar 22:105345. doi: 10.1016/j.nbd.2021.105345.
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  135. OJO J, Eisenbaum M, Shackleton B, Lynch C, et al
    Mural cell dysfunction leads to altered cerebrovascular tau uptake following repetitive head trauma.
    Neurobiol Dis. 2021;150:105237.
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    February 2021
  136. TSAI AP, Lin PB, Dong C, Moutinho M, et al
    INPP5D expression is associated with risk for Alzheimer's disease and induced by plaque-associated microglia.
    Neurobiol Dis. 2021 Feb 22:105303. doi: 10.1016/j.nbd.2021.105303.
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  137. BASAK JM, Ferreiro A, Cohen LS, Sheehan PW, et al
    Bacterial sepsis increases hippocampal fibrillar amyloid plaque load and neuroinflammation in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2021;152:105292.
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  138. XUE F, Tian J, Yu C, Du H, et al
    Type I interferon response-related microglial Mef2c deregulation at the onset of Alzheimer's pathology in 5xFAD mice.
    Neurobiol Dis. 2021 Feb 1:105272. doi: 10.1016/j.nbd.2021.105272.
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  139. NOORI A, Mezlini AM, Hyman BT, Serrano-Pozo A, et al
    Systematic review and meta-analysis of human transcriptomics reveals neuroinflammation, deficient energy metabolism, and proteostasis failure across neurodegeneration.
    Neurobiol Dis. 2021;149:105225.
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    January 2021
  140. ALCANTARA-GONZALEZ D, Chartampila E, Criscuolo C, Scharfman HE, et al
    Early changes in synaptic and intrinsic properties of dentate gyrus granule cells in a mouse model of Alzheimer's disease neuropathology and atypical effects of the cholinergic antagonist atropine.
    Neurobiol Dis. 2021 Jan 20:105274. doi: 10.1016/j.nbd.2021.105274.
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  141. KOW RL, Strovas TJ, McMillan PJ, Jacobi AM, et al
    Distinct Poly(A) nucleases have differential impact on sut-2 dependent tauopathy phenotypes.
    Neurobiol Dis. 2021;147:105148.
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  142. ALCALA-VIDA R, Awada A, Boutillier AL, Merienne K, et al
    Epigenetic mechanisms underlying enhancer modulation of neuronal identity, neuronal activity and neurodegeneration.
    Neurobiol Dis. 2021;147:105155.
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  143. LAMBRACHT-WASHINGTON D, Fu M, Hynan LS, Rosenberg RN, et al
    Changes in the brain transcriptome after DNA Abeta42 trimer immunization in a 3xTg-AD mouse model.
    Neurobiol Dis. 2021;148:105221.
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    December 2020
  144. CALIO ML, Mosini AC, Marinho DS, Salles GN, et al
    Leptin enhances adult neurogenesis and reduces pathological features in a transgenic mouse model of Alzheimer's disease.
    Neurobiol Dis. 2020 Dec 7:105219. doi: 10.1016/j.nbd.2020.105219.
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  145. PIMENOVA AA, Herbinet M, Gupta I, Machlovi SI, et al
    Alzheimer's-associated PU.1 expression levels regulate microglial inflammatory response.
    Neurobiol Dis. 2020 Dec 7:105217. doi: 10.1016/j.nbd.2020.105217.
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    November 2020
  146. ANDERSEN JV, Christensen SK, Westi EW, Diaz-delCastillo M, et al
    Deficient astrocyte metabolism impairs glutamine synthesis and neurotransmitter homeostasis in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2020 Nov 23:105198. doi: 10.1016/j.nbd.2020.105198.
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    October 2020
  147. PENTZ R, Iulita MF, Mikutra-Cencora M, Ducatenzeiler A, et al
    A new role for matrix metalloproteinase-3 in the NGF metabolic pathway: Proteolysis of mature NGF and sex-specific differences in the continuum of Alzheimer's pathology.
    Neurobiol Dis. 2020 Oct 29:105150. doi: 10.1016/j.nbd.2020.105150.
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  148. MONTALBANO M, McAllen S, Cascio FL, Sengupta U, et al
    TDP-43 and tau oligomers in Alzheimer's disease, amyotrophic lateral sclerosis, and frontotemporal dementia.
    Neurobiol Dis. 2020 Oct 13:105130. doi: 10.1016/j.nbd.2020.105130.
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  149. STEPLER KE, Mahoney ER, Kofler J, Hohman TJ, et al
    Inclusion of African American/black adults in a pilot brain proteomics study of Alzheimer's disease.
    Neurobiol Dis. 2020 Oct 10:105129. doi: 10.1016/j.nbd.2020.105129.
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    June 2020
  150. PETRUSHINA I, Hovakimyan A, Harahap-Carrillo IS, Davtyan H, et al
    Characterization and preclinical evaluation of the cGMP grade DNA based vaccine, AV-1959D to enter the first-in-human clinical trials.
    Neurobiol Dis. 2020;139:104823.
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  151. DIOUF I, Bush AI, Ayton S
    Cerebrospinal fluid ceruloplasmin levels predict cognitive decline and brain atrophy in people with underlying beta-amyloid pathology.
    Neurobiol Dis. 2020;139:104810.
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  152. HSU S, Pimenova AA, Hayes K, Villa JA, et al
    Systematic validation of variants of unknown significance in APP, PSEN1 and PSEN2.
    Neurobiol Dis. 2020;139:104817.
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  153. BORRECA A, Valeri F, De Luca M, Ernst L, et al
    Transient upregulation of translational efficiency in prodromal and early symptomatic Tg2576 mice contributes to Abeta pathology.
    Neurobiol Dis. 2020;139:104787.
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    May 2020
  154. PIMENOVA AA, Goate AM
    Novel presenilin 1 and 2 double knock-out cell line for in vitro validation of PSEN1 and PSEN2 mutations.
    Neurobiol Dis. 2020;138:104785.
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  155. WISNIEWSKI T, Drummond E
    APOE-amyloid interaction: Therapeutic targets.
    Neurobiol Dis. 2020;138:104784.
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    April 2020
  156. MAKARAVA N, Chang JC, Molesworth K, Baskakov IV, et al
    Region-specific glial homeostatic signature in prion diseases is replaced by a uniform neuroinflammation signature, common for brain regions and prion strains with different cell tropism.
    Neurobiol Dis. 2020;137:104783.
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  157. RHEA EM, Raber J, Banks WA
    ApoE and cerebral insulin: Trafficking, receptors, and resistance.
    Neurobiol Dis. 2020;137:104755.
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    March 2020
  158. FLOWERS SA, Rebeck GW
    APOE in the normal brain.
    Neurobiol Dis. 2020;136:104724.
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    February 2020
  159. BITTAR A, Bhatt N, Kayed R
    Advances and considerations in AD tau-targeted immunotherapy.
    Neurobiol Dis. 2020;134:104707.
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  160. AFGHAH Z, Chen X, Geiger JD
    Role of endolysosomes and inter-organellar signaling in brain disease.
    Neurobiol Dis. 2020;134:104670.
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  161. SOLTI K, Kuan WL, Forizs B, Kustos G, et al
    DJ-1 can form beta-sheet structured aggregates that co-localize with pathological amyloid deposits.
    Neurobiol Dis. 2020;134:104629.
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  162. WEI Z, Meng X, El Fatimy R, Sun B, et al
    Environmental enrichment prevents Abeta oligomer-induced synaptic dysfunction through mirna-132 and hdac3 signaling pathways.
    Neurobiol Dis. 2020;134:104617.
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  163. HOGLUND K, Schussler N, Kvartsberg H, Smailovic U, et al
    Cerebrospinal fluid neurogranin in an inducible mouse model of neurodegeneration: A translatable marker of synaptic degeneration.
    Neurobiol Dis. 2020;134:104645.
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    January 2020
  164. SCHWAB AD, Thurston MJ, Machhi J, Olson KE, et al
    Immunotherapy for Parkinson's disease.
    Neurobiol Dis. 2020;137:104760.
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