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Alzheimer's Disease

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Articles published in
Nature
    September 2022
  1. PRILLAMAN M
    Alzheimer's drug slows mental decline in trial - but is it a breakthrough?
    Nature. 2022 Sep 29. pii: 10.1038/d41586-022-03081.
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    July 2022
  2. NAIK S, Fuchs E
    Inflammatory memory and tissue adaptation in sickness and in health.
    Nature. 2022;607:249-255.
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  3. ZHOU Y, Su Y, Li S, Kennedy BC, et al
    Molecular landscapes of human hippocampal immature neurons across lifespan.
    Nature. 2022;607:527-533.
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    June 2022
  4. KARLAWISH J
    Fix the process that led to Alzheimer's drug fiasco.
    Nature. 2022;606:9.
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    May 2022
  5. KOZLOV M
    Will the FDA change how it vets drugs following the Alzheimer's debacle?
    Nature. 2022 May 13. pii: 10.1038/d41586-022-01316.
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    April 2022
  6. MILLER MB, Huang AY, Kim J, Zhou Z, et al
    Somatic genomic changes in single Alzheimer's disease neurons.
    Nature. 2022 Apr 20. pii: 10.1038/s41586-022-04640.
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    March 2022
  7. STEWART L
    The coin toss of Alzheimer's inheritance.
    Nature. 2022 Mar 17. pii: 10.1038/d41586-022-00659.
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  8. XIONG J, Kang SS, Wang Z, Liu X, et al
    FSH blockade improves cognition in mice with Alzheimer's disease.
    Nature. 2022 Mar 2. pii: 10.1038/s41586-022-04463.
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  9. A pituitary hormone has a key role in Alzheimer's disease.
    Nature. 2022 Mar 2. pii: 10.1038/d41586-022-00530.
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  10. ABBOTT A
    Could drugs prevent Alzheimer's? These trials aim to find out.
    Nature. 2022;603:216-219.
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    February 2022
  11. YANG AC, Vest RT, Kern F, Lee DP, et al
    A human brain vascular atlas reveals diverse mediators of Alzheimer's risk.
    Nature. 2022 Feb 14. pii: 10.1038/s41586-021-04369.
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  12. Molecular map of the human blood-brain barrier reveals links to Alzheimer's disease.
    Nature. 2022 Feb 14. pii: 10.1038/d41586-022-00350.
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    December 2021
  13. DE MIGUEL Z, Khoury N, Betley MJ, Lehallier B, et al
    Exercise plasma boosts memory and dampens brain inflammation via clusterin.
    Nature. 2021;600:494-499.
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    November 2021
  14. ROBINSON A
    Defining Alzheimer's, and the climate costs of AI: Books in brief.
    Nature. 2021 Nov 19. pii: 10.1038/d41586-021-03484.
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  15. MULLARD A
    More Alzheimer's drugs head for FDA review: what scientists are watching.
    Nature. 2021 Nov 15. pii: 10.1038/d41586-021-03410.
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    October 2021
  16. STAHLBERG H, Riek R
    Structural strains of misfolded tau protein define different diseases.
    Nature. 2021;598:264-265.
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  17. BERG J, Sorensen SA, Ting JT, Miller JA, et al
    Human neocortical expansion involves glutamatergic neuron diversification.
    Nature. 2021;598:151-158.
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    July 2021
  18. BARRON JJ, Molofsky AV
    A protective signal between the brain's supporting cells in Alzheimer's disease.
    Nature. 2021 Jul 14. pii: 10.1038/d41586-021-01870.
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  19. MCALPINE CS, Park J, Griciuc A, Kim E, et al
    Astrocytic interleukin-3 programs microglia and limits Alzheimer's disease.
    Nature. 2021 Jul 14. pii: 10.1038/s41586-021-03734.
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    June 2021
  20. MULLARD A
    Controversial Alzheimer's drug approval could affect other diseases.
    Nature. 2021 Jun 29. pii: 10.1038/d41586-021-01763.
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  21. GRAHAM F
    Daily briefing: Alzheimer's drug controversially approved by FDA.
    Nature. 2021 Jun 8. pii: 10.1038/d41586-021-01553.
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  22. MULLARD A
    Landmark Alzheimer's drug approval confounds research community.
    Nature. 2021 Jun 8. pii: 10.1038/d41586-021-01546.
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    May 2021
  23. ABASCAL F, Harvey LMR, Mitchell E, Lawson ARJ, et al
    Somatic mutation landscapes at single-molecule resolution.
    Nature. 2021;593:405-410.
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  24. DA MESQUITA S, Papadopoulos Z, Dykstra T, Brase L, et al
    Meningeal lymphatics affect microglia responses and anti-Abeta immunotherapy.
    Nature. 2021;593:255-260.
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    February 2021
  25. WILLYARD C
    How gut microbes could drive brain disorders.
    Nature. 2021;590:22-25.
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    January 2021
  26. ELSE H
    The science events to watch for in 2021.
    Nature. 2021;589:14-15.
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    November 2020
  27. ABBOTT A
    Are infections seeding some cases of Alzheimer's disease?
    Nature. 2020;587:22-25.
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    September 2020
  28. HUR JY, Frost GR, Wu X, Crump C, et al
    The innate immunity protein IFITM3 modulates gamma-secretase in Alzheimer's disease.
    Nature. 2020 Sep 2. pii: 10.1038/s41586-020-2681.
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    June 2020
  29. ABBOTT A
    Thousands of people will help scientists to track the long-term health effects of the coronavirus crisis.
    Nature. 2020;582:326.
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    May 2020
  30. MONTAGNE A, Nation DA, Sagare AP, Barisano G, et al
    APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline.
    Nature. 2020;581:71-76.
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    April 2020
  31. ISHII M, Iadecola C
    Risk factor for Alzheimer's disease breaks the blood-brain barrier.
    Nature. 2020 Apr 29. pii: 10.1038/d41586-020-01152.
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  32. DEINHARDT K
    A receptor that lets dementia-associated tau proteins into neurons.
    Nature. 2020;580:326-327.
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  33. ZHANG W, Tarutani A, Newell KL, Murzin AG, et al
    Novel tau filament fold in corticobasal degeneration.
    Nature. 2020;580:283-287.
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    February 2020
  34. O'MEARA S
    The neurobiologist studying how the brain changes as it ages.
    Nature. 2020;578:S3.
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    January 2020
  35. GATE D, Saligrama N, Leventhal O, Yang AC, et al
    Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease.
    Nature. 2020 Jan 8. pii: 10.1038/s41586-019-1895.
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  36. HENEKA MT
    An immune-cell signature marks the brain in Alzheimer's disease.
    Nature. 2020;577:322-323.
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    October 2019

  37. Swine flu snipers, Alzheimer's drug push and Google's latest gaming bot.
    Nature. 2019;574:602-603.
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  38. FARACO G, Hochrainer K, Segarra SG, Schaeffer S, et al
    Dietary salt promotes cognitive impairment through tau phosphorylation.
    Nature. 2019;574:686-690.
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    July 2019
  39. GRAVITZ L
    The forgotten part of memory.
    Nature. 2019;571:S12-S14.
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    May 2019
  40. MAXMEN A
    The devastating biological consequences of homelessness.
    Nature. 2019;569:467-468.
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    April 2019
  41. FALCON B, Zivanov J, Zhang W, Murzin AG, et al
    Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules.
    Nature. 2019;568:420-423.
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