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Articles published in
J Neurochem
    April 2025
  1. REHMAN AS, Tasleem A, Ali N, Khan R, et al
    Donepezil Improves PSD95 Expression, Mitigates Neuroinflammation via PI3K/Akt/NF-kappaB and Mitochondrial Dysfunction in a Rodent Model of Subarachnoid Haemorrhage.
    J Neurochem. 2025;169:e70063.
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    March 2025
  2. BONG SH, Choi H, Song HH, Kim DK, et al
    Metabolic Reprogramming in Primary Microglial Cell and Extracellular Vesicle Triggered by Abeta Exposure.
    J Neurochem. 2025;169:e70030.
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  3. YANG J, Pu YL, Pan QL, Wang L, et al
    CPNE7 Regulates Amyloidogenesis Through CAP1-Dependent ADAM10 Translation.
    J Neurochem. 2025;169:e70026.
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  4. AL-THANI NA, Stewart GS, Costello DA
    The Role of the Urea Cycle in the Alzheimer's Disease Brain.
    J Neurochem. 2025;169:e70033.
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  5. HEYLEN A, Vermeiren Y, De Deyn PP, Van Dam D, et al
    Monoaminergic Alterations at the Subregional Cervical and Thoracic Spinal Cord Level of Patients Within the FTD-ALS Continuum and Early-Onset AD: Low Thoracic Dopaminergic Activity in ALS.
    J Neurochem. 2025;169:e70046.
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  6. ALSHAEBI F, Sciortino A, Kayed R
    The Role of Glial Cell Senescence in Alzheimer's Disease.
    J Neurochem. 2025;169:e70051.
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    February 2025
  7. FU X, Quan S, Liang W, Li Y, et al
    FOXP1 is a Transcription Factor for the Alzheimer's Disease Risk Gene SORL1.
    J Neurochem. 2025;169:e70011.
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  8. NOVACK GV, Galeano P, Defelipe LA, Campanelli L, et al
    The Supramolecular Architecture of Mitochondrial Complex I in the Rat Brain Is Altered by Alzheimer's-Like Cerebral Amyloidosis.
    J Neurochem. 2025;169:e70017.
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  9. DIVYA, Faruq M, Nazir SS, Kaushik P, et al
    Ganaxolone Reverses the Effect of Amyloid beta-Induced Neurotoxicity by Regulating the Liver X Receptor Expression in APP Transfected SH-SY5Y Cells and Murine Model of Alzheimer's Disease.
    J Neurochem. 2025;169:e70007.
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  10. TISI A, Scipioni L, Carozza G, Di Re L, et al
    Alterations of endocannabinoid signaling and microglia reactivity in the retinas of AD-like mice precede the onset of hippocampal beta-amyloid plaques.
    J Neurochem. 2025;169:e16256.
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  11. SHARMIN T, Chatterjee P, Doecke JD, Ashton NJ, et al
    Circulating medium- and long-chain acylcarnitines are associated with plasma P-tau181 in cognitively normal older adults.
    J Neurochem. 2025;169:10.
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    January 2025
  12. ELSWORTHY RJ, Finelli MJ, Aqattan S, Dunleavy C, et al
    Altered metabolic function induced by Abeta-oligomers and PSEN1 mutations in iPSC-derived astrocytes.
    J Neurochem. 2025;169:e16267.
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  13. MENG J, Lei P
    Testing cognitive normal for Alzheimer's disease prediction.
    J Neurochem. 2025;169:e16272.
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  14. TSERING W, de la Rosa A, Ruan IY, Philips JL, et al
    Preferential clustering of microglia and astrocytes around neuritic plaques during progression of Alzheimer's disease neuropathological changes.
    J Neurochem. 2025;169:e16275.
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  15. HE Y, Zhu P, Gao S, Wu S, et al
    Identification of Alzheimer's disease susceptibility genes by integrating eight human brain single-cell transcriptomes with genome-wide association studies.
    J Neurochem. 2025;169:e16276.
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  16. EXPRESSION OF CONCERN: Potent Anti-amyloidogenic and Fibril-destabilizing Effects of Polyphenols In Vitro: Implications for the Prevention and Therapeutics of Alzheimer's Disease.
    J Neurochem. 2025;169:e16285.
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  17. PFITZER J, Pinky PD, Perman S, Redmon E, et al
    Troriluzole rescues glutamatergic deficits, amyloid and tau pathology, and synaptic and memory impairments in 3xTg-AD mice.
    J Neurochem. 2025;169:e16215.
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  18. WANG YC, Huang LY, Guo HH, Liu M, et al
    Higher CSF sTREM2 attenuates APOE epsilon4-related risk for amyloid pathology in cognitively intact adults: The CABLE study.
    J Neurochem. 2025;169:e16273.
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  19. PAWLOSKY R, Demarest TG, King MT, Estrada D, et al
    Effect of Dietary Ketosis and Nicotinamide Riboside on Hippocampal Krebs Cycle Intermediates and Mitochondrial Energetics in a DNA Repair-Deficient 3xTg/POLbeta(+/-) Alzheimer Disease Mouse Model.
    J Neurochem. 2025;169:e16295.
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  20. ROHR D, Helfrich M, Horing M, Grosseruschkamp F, et al
    Unsaturated Fatty Acids Are Decreased in Abeta Plaques in Alzheimer's Disease.
    J Neurochem. 2025;169:e16306.
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    November 2024
  21. CHEN YH, Wang ZB, Liu XP, Mao ZQ, et al
    Elevated serum sodium is linked to increased amyloid-dependent tau pathology, neurodegeneration, and cognitive impairment in Alzheimer's disease.
    J Neurochem. 2024 Nov 6. doi: 10.1111/jnc.16257.
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    October 2024
  22. XU F, Wu S, Gao S, Li X, et al
    Causal association between insulin sensitivity index and Alzheimer's disease.
    J Neurochem. 2024 Oct 31. doi: 10.1111/jnc.16254.
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    September 2024
  23. MITIAS S, Schaffer N, Nair S, Hook C, et al
    ProSAAS is preferentially up-regulated during homeostatic scaling and reduces amyloid plaque burden in the 5xFAD mouse hippocampus.
    J Neurochem. 2024;168:3235-3249.
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  24. STROPE TA, Wilkins HM
    The reciprocal relationship between amyloid precursor protein and mitochondrial function.
    J Neurochem. 2024;168:2275-2284.
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  25. XIONG M, Dahlen A, Roshanbin S, Wik E, et al
    Antibody engagement with amyloid-beta does not inhibit [(11)C]PiB binding for PET imaging.
    J Neurochem. 2024;168:2601-2610.
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  26. MA LY, Song JH, Gao PY, Ou YN, et al
    Amyloid pathology mediates the associations between plasma fibrinogen and cognition in non-demented adults.
    J Neurochem. 2024;168:2532-2542.
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  27. LOGSDON AF, Foresi B, Hu SJ, Quah E, et al
    Perineuronal net deglycosylation associates with tauopathy-induced gliosis and neurodegeneration.
    J Neurochem. 2024;168:1923-1936.
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  28. AMONTREE M, Nelson M, Stefansson L, Pak D, et al
    Resveratrol differentially affects MMP-9 release from neurons and glia; implications for therapeutic efficacy.
    J Neurochem. 2024;168:1895-1908.
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    July 2024
  29. DEN HOEDT S, Crivelli SM, Dorst-Lagerwerf KY, Leijten FPJ, et al
    The effects of APOE4 and familial Alzheimer's disease mutations on free fatty acid profiles in mouse brain are age- and sex-dependent.
    J Neurochem. 2024 Jul 13. doi: 10.1111/jnc.16176.
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  30. HUANG HX, Inglese P, Tang J, Yagoubi R, et al
    Mass spectrometry imaging highlights dynamic patterns of lipid co-expression with Abeta plaques in mouse and human brains.
    J Neurochem. 2024;168:1193-1214.
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  31. VAN DEN BERG E, Kersten I, Brinkmalm G, Johansson K, et al
    Profiling amyloid-beta peptides as biomarkers for cerebral amyloid angiopathy.
    J Neurochem. 2024;168:1254-1264.
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    June 2024
  32. ISEI MO, Girardi PA, Rodwell-Bullock J, Nehrke K, et al
    Site-specific phosphorylation of tau impacts mitochondrial function and response to stressors.
    J Neurochem. 2024;168:1019-1029.
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    May 2024
  33. CHEN Y, Zeng X, Diaz JL, Sehrawat A, et al
    Effect of blood collection tube containing protease inhibitors on the pre-analytical stability of Alzheimer's disease plasma biomarkers.
    J Neurochem. 2024 May 30. doi: 10.1111/jnc.16130.
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    April 2024

  34. The following article for this Special Issue was previously published and can be found in its respective issue online: "Detection of early Alzheimer's disease-like molecular alterations in a mouse model expressing human ApoE4".
    J Neurochem. 2024;168:e2.
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  35. KWAN KH, Soreq H
    EDITOR SPOTLIGHT: Interview with Cholinergic Mechanisms Special Issue Guest Editor Hermona Soreq.
    J Neurochem. 2024;168:331-333.
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    March 2024
  36. NETZAHUALCOYOTZI C, Santillan-Cigales JJ, Adalid-Peralta LV, Velasco I, et al
    Infiltration of immune cells to the brain and its relation to the pathogenesis of Alzheimer's and Parkinson's diseases.
    J Neurochem. 2024 Mar 29. doi: 10.1111/jnc.16106.
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  37. ZHANG JF, Fang ZT, Zhao JN, Liu GP, et al
    Acetylated tau exacerbates apoptosis by disturbing mitochondrial dynamics in HEK293 cells.
    J Neurochem. 2024;168:288-302.
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    February 2024
  38. PEREIRA JD, Teixeira LCR, Mamede I, Alves MT, et al
    miRNAs in cerebrospinal fluid associated with Alzheimer's disease: A systematic review and pathway analysis using a data mining and machine learning approach.
    J Neurochem. 2024 Feb 23. doi: 10.1111/jnc.16060.
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  39. HANRIEDER J
    Lipid imaging of Alzheimer's disease pathology.
    J Neurochem. 2024 Feb 19. doi: 10.1111/jnc.16079.
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  40. FERNANDES T, Melo T, Conde T, Neves B, et al
    Mapping the lipidome in mitochondria-associated membranes (MAMs) in an in vitro model of Alzheimer's disease.
    J Neurochem. 2024 Feb 7. doi: 10.1111/jnc.16072.
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  41. LIANG Y, Deng MG, Jian Q, Liu M, et al
    Maternal history of Alzheimer's disease predisposes to altered serum cholesterol levels in adult offspring.
    J Neurochem. 2024 Feb 5. doi: 10.1111/jnc.16056.
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  42. SU M, Xuan E, Sun X, Pan G, et al
    Synaptic adhesion molecule protocadherin-gammaC5 mediates beta-amyloid-induced neuronal hyperactivity and cognitive deficits in Alzheimer's disease.
    J Neurochem. 2024 Feb 3. doi: 10.1111/jnc.16066.
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  43. FRANCIS JS, Nguyen Q, Markov V, Leone P, et al
    Over-expression of N-acetylaspartate synthase exacerbates pathological energetic deficit and accelerates cognitive decline in the 5xFAD mouse.
    J Neurochem. 2024;168:69-82.
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    December 2023
  44. SALCEDO C, Pozo Garcia V, Garcia-Adan B, Ameen AO, et al
    Increased glucose metabolism and impaired glutamate transport in human astrocytes are potential early triggers of abnormal extracellular glutamate accumulation in hiPSC-derived models of Alzheimer's disease.
    J Neurochem. 2023 Dec 8. doi: 10.1111/jnc.16014.
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  45. GAO PY, Ou YN, Huang YM, Wang ZB, et al
    Associations between liver function and cerebrospinal fluid biomarkers of Alzheimer's disease pathology in non-demented adults: The CABLE study.
    J Neurochem. 2023 Dec 6. doi: 10.1111/jnc.16025.
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  46. HUANG SY, Zhang YR, Yang L, Li YZ, et al
    Circulating metabolites and risk of incident dementia: A prospective cohort study.
    J Neurochem. 2023;167:668-679.
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    November 2023
  47. QIN H, Zhou L, Haque FT, Martin-Jimenez C, et al
    Diverse signaling mechanisms and heterogeneity of astrocyte reactivity in Alzheimer's disease.
    J Neurochem. 2023 Nov 6. doi: 10.1111/jnc.16002.
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  48. HAMILTON K, Morrow K, Markantoni E, Harvey J, et al
    Leptin prevents aberrant targeting of tau to hippocampal synapses via PI 3 kinase driven inhibition of GSK3beta.
    J Neurochem. 2023;167:520-537.
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    October 2023
  49. FURMAN S, Green K, Lane TE
    COVID-19 and the impact on Alzheimer's disease pathology.
    J Neurochem. 2023 Oct 18. doi: 10.1111/jnc.15985.
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  50. TURNER AJ
    Book Review: Alzheimer's Disease Research: What has guided research so far and why it is high time for a paradigm shift (Christian Behl. Springer Nature, Switzerland, 2023) 661 pp.
    J Neurochem. 2023 Oct 14. doi: 10.1111/jnc.15989.
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  51. SAMUELS JD, Lukens JR, Price RJ
    Emerging roles for ITAM and ITIM receptor signaling in microglial biology and Alzheimer's disease-related amyloidosis.
    J Neurochem. 2023 Oct 11. doi: 10.1111/jnc.15981.
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    September 2023
  52. WANG R, Lu KP, Zhou XZ
    Function and regulation of cis P-tau in the pathogenesis and treatment of conventional and nonconventional tauopathies.
    J Neurochem. 2023;166:904-914.
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  53. SAEZ-VALERO J, Perez-Gonzalez R
    BACE2 beyond beta-processing of APP, its neuroprotective role in cerebrovascular endothelium.
    J Neurochem. 2023;166:887-890.
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  54. CHENG JY, Deng YT, Yu JT
    The causal role of circulating amino acids on neurodegenerative disorders: A two-sample Mendelian randomization study.
    J Neurochem. 2023;166:972-981.
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    August 2023
  55. LAU SF, Fu AKY, Ip NY
    Receptor-ligand interaction controls microglial chemotaxis and amelioration of Alzheimer's disease pathology.
    J Neurochem. 2023 Aug 21. doi: 10.1111/jnc.15933.
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  56. CUENCA-BERMEJO L, Prinetti A, Kublickiene K, Raparelli V, et al
    Fundamental neurochemistry review: Old brain stories - Influence of age and sex on the neurodegeneration-associated lipid changes.
    J Neurochem. 2023;166:427-452.
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    July 2023
  57. WARTH PEREZ ARIAS CC, Silbern I, Caldi Gomes L, Wartmann H, et al
    Proteomic analysis of the human hippocampus identifies neuronal pentraxin 1 (NPTX1) as synapto-axonal target in late-stage Parkinson's disease.
    J Neurochem. 2023 Jul 28. doi: 10.1111/jnc.15924.
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  58. RAI A, Ojiakor OA, Rylett RJ
    Detection of early Alzheimer's disease-like molecular alterations in a mouse model expressing human ApoE4.
    J Neurochem. 2023 Jul 6. doi: 10.1111/jnc.15904.
    >> Share

  59. MOREIRA GG, Gomes CM
    Tau liquid-liquid phase separation is modulated by the Ca(2+) -switched chaperone activity of the S100B protein.
    J Neurochem. 2023;166:76-86.
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  60. MATAFORA V, Gorb A, Yang F, Noble W, et al
    Proteomics of the astrocyte secretome reveals changes in their response to soluble oligomeric Abeta.
    J Neurochem. 2023;166:346-366.
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  61. SECKER C, Motzny AY, Kostova S, Buntru A, et al
    The polyphenol EGCG directly targets intracellular amyloid-beta aggregates and promotes their lysosomal degradation.
    J Neurochem. 2023;166:294-317.
    >> Share

  62. SANTIAGO TC, Parra L, Nani JV, Fidalgo TM, et al
    Angiotensin-converting enzymes as druggable features of psychiatric and neurodegenerative disorders.
    J Neurochem. 2023;166:138-155.
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    June 2023
  63. ANDERSON T, Sharma S, Kelberman MA, Ware C, et al
    Obesity during preclinical Alzheimer's disease development exacerbates brain metabolic decline.
    J Neurochem. 2023 Jun 30. doi: 10.1111/jnc.15900.
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  64. MAKSOUR S, Ooi L
    Innovations advancing our understanding of microglia in Alzheimer's disease: From in vitro to in vivo models.
    J Neurochem. 2023 Jun 15. doi: 10.1111/jnc.15885.
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  65. ZHAO Y, Zhou H, Zhao Y, Liang Z, et al
    BACE1 SUMOylation deregulates phosphorylation and ubiquitination in Alzheimer's disease pathology.
    J Neurochem. 2023 Jun 7. doi: 10.1111/jnc.15870.
    >> Share

  66. HE RB, Li L, Liu LZ, Ma YJ, et al
    Ceftriaxone improves impairments in synaptic plasticity and cognitive behavior in APP/PS1 mouse model of Alzheimer's disease by inhibiting extrasynaptic NMDAR-STEP(61) signaling.
    J Neurochem. 2023 Jun 7. doi: 10.1111/jnc.15874.
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  67. BARINGER SL, Simpson IA, Connor JR
    Brain iron acquisition: An overview of homeostatic regulation and disease dysregulation.
    J Neurochem. 2023;165:625-642.
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  68. GROVER S, Pham T, Jones A, Sinobas-Pereira C, et al
    A new class of monoclonal Abeta antibodies selectively targets and triggers deposition of Abeta protofibrils.
    J Neurochem. 2023;165:860-873.
    >> Share

  69. DOHERTY G, Holiday A, Malekizadeh Y, Manolescu C, et al
    Leptin-based hexamers facilitate memory and prevent amyloid-driven AMPA receptor internalisation and neuronal degeneration.
    J Neurochem. 2023;165:809-826.
    >> Share

    May 2023
  70. FLEEMAN RM, Kuhn MK, Chan DC, Proctor EA, et al
    Apolipoprotein E epsilon4 modulates astrocyte neuronal support functions in the presence of amyloid-beta.
    J Neurochem. 2023;165:536-549.
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    April 2023
  71. MOK KK, Yeung SH, Cheng GW, Ma IW, et al
    Apolipoprotein E epsilon4 disrupts oligodendrocyte differentiation by interfering with astrocyte-derived lipid transport.
    J Neurochem. 2023;165:55-75.
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    March 2023
  72. CARNA M, Novotny JS, Dragisic N, Slavik H, et al
    Missorting of Plasma miRNAs in Aging and Alzheimer's Disease.
    J Neurochem. 2023 Mar 9. doi: 10.1111/jnc.15801.
    >> Share

  73. WENZEL TJ, Le J, He J, Alcorn J, et al
    Fundamental Neurochemistry Review: Incorporating a greater diversity of cell types, including microglia, in brain organoid cultures improves clinical translation.
    J Neurochem. 2023;164:560-582.
    >> Share

  74. LOEFFLER DA
    Experimental approaches for altering the expression of Abeta-degrading enzymes.
    J Neurochem. 2023;164:725-763.
    >> Share

  75. SUN Y, Islam S, Gao Y, Nakamura T, et al
    Apolipoprotein E4 inhibits gamma-secretase activity via binding to the gamma-secretase complex.
    J Neurochem. 2023;164:858-874.
    >> Share

  76. TORTUYAUX R, Avila-Gutierrez K, Oudart M, Mazare N, et al
    Physiopathological changes of ferritin mRNA density and distribution in hippocampal astrocytes in the mouse brain.
    J Neurochem. 2023;164:847-857.
    >> Share

    February 2023
  77. HOENIG MC, Drzezga A
    Clear-headed into old age: Resilience and resistance against brain aging-A PET imaging perspective.
    J Neurochem. 2023;164:325-345.
    >> Share


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