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Alzheimer's Disease

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Articles published in
J Neurochem
    November 2021
  1. MA T
    Roles of eukaryotic elongation factor 2 kinase (eEF2K) in neuronal plasticity, cognition, and Alzheimer's disease.
    J Neurochem. 2021 Nov 19. doi: 10.1111/jnc.15541.
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  2. MATUSZYK MM, Garwood CJ, Ferraiuolo L, Simpson JE, et al
    Biological and Methodological Complexities of Beta-Amyloid Peptide; Implications for Alzheimer's Disease Research.
    J Neurochem. 2021 Nov 12. doi: 10.1111/jnc.15538.
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  3. ZULIANI G, Trentini A, Brombo G, Rosta V, et al
    Serum beta-secretase 1 (BACE1) activity increases in patients with mild cognitive impairment.
    J Neurochem. 2021;159:629-637.
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    October 2021
    Preface: Mass spectrometry in Alzheimer disease: This is the Preface for the special issue "Mass Spectrometry in Alzheimer Disease".
    J Neurochem. 2021;159:207-210.
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  5. GKANATSIOU E, Nilsson J, Toomey CE, Vrillon A, et al
    Amyloid pathology and synaptic loss in pathological aging.
    J Neurochem. 2021;159:258-272.
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    September 2021
  6. JAKARIA M, Belaidi AA, Bush AI, Ayton S, et al
    Ferroptosis as a mechanism of neurodegeneration in Alzheimer's disease.
    J Neurochem. 2021 Sep 23. doi: 10.1111/jnc.15519.
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  7. GEULA C, Dunlop SR, Ayala I, Kawles AS, et al
    Basal forebrain cholinergic system in the dementias: Vulnerability, resilience, and resistance.
    J Neurochem. 2021;158:1394-1411.
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    July 2021
  8. MICHNO W, Blennow K, Zetterberg H, Brinkmalm G, et al
    Refining the amyloid beta peptide and oligomer fingerprint ambiguities in Alzheimer's disease: mass spectrometric molecular characterization in brain, CSF, blood and plasma.
    J Neurochem. 2021 Jul 10. doi: 10.1111/jnc.15466.
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  9. KORECKA M, Shaw LM
    Mass spectrometry-based methods for robust measurement of Alzheimer's Disease biomarkers in biological fluids.
    J Neurochem. 2021 Jul 10. doi: 10.1111/jnc.15465.
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  10. Retraction: Clinical trials in Alzheimer's disease': immunotherapy approaches.
    J Neurochem. 2021 Jul 6. doi: 10.1111/jnc.15435.
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  11. WANG XM, Zeng P, Fang YY, Zhang T, et al
    Progranulin in neurodegenerative dementia.
    J Neurochem. 2021;158:119-137.
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  12. XU L, Tian S, Peng X, Hua Y, et al
    Clusterin inhibits Abeta42 aggregation through a "strawberry model" as detected by FRET-FCS.
    J Neurochem. 2021;158:444-454.
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    June 2021
  13. CORTES-GOMEZ MA, Llorens-Alvarez E, Alom J, Del Ser T, et al
    Tau phosphorylation by glycogen synthase kinase 3beta modulates enzyme acetylcholinesterase expression.
    J Neurochem. 2021;157:2091-2105.
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    May 2021
  14. LI KY, Xiang XJ, Song L, Chen J, et al
    Mitochondrial TXN2 attenuates amyloidogenesis via selective inhibition of BACE1 expression.
    J Neurochem. 2021;157:1351-1365.
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    April 2021
  15. LEE-LIU D, Gonzalez-Billault C
    Neuron-intrinsic origin of hyperexcitability during early pathogenesis of Alzheimer's disease: An Editorial Highlight for "Hippocampal hyperactivity in a rat model of Alzheimer's disease" on
    J Neurochem. 2021 Apr 28. doi: 10.1111/jnc.15248.
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  16. SUN L, Bhawal R, Xu H, Chen H, et al
    The human brain acetylome reveals that decreased acetylation of mitochondrial proteins associates with Alzheimer's disease.
    J Neurochem. 2021 Apr 27. doi: 10.1111/jnc.15377.
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  17. VAN DER VELPEN V, Rosenberg N, Maillard V, Teav T, et al
    Sex-specific alterations in NAD+ metabolism in triple transgenic Alzheimer's disease mouse brain assessed by quantitative targeted liquid chromatography - mass spectrometry.
    J Neurochem. 2021 Apr 8. doi: 10.1111/jnc.15362.
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    March 2021
  18. BUTLER CA, Thornton P, Brown GC
    CD33M inhibits microglial phagocytosis, migration and proliferation, but the Alzheimer's disease-protective variant CD33m stimulates phagocytosis and proliferation, and inhibits adhesion.
    J Neurochem. 2021 Mar 15. doi: 10.1111/jnc.15349.
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  19. CHEN H, Cross AC, Thakkar A, Xu H, et al
    Selective linkage of mitochondrial enzymes to intracellular calcium stores differs between human-induced pluripotent stem cells, neural stem cells, and neurons.
    J Neurochem. 2021;156:867-879.
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    February 2021
  20. SOSULINA L, Mittag M, Geis HR, Hoffmann K, et al
    Hippocampal hyperactivity in a rat model of Alzheimer's disease.
    J Neurochem. 2021 Feb 14. doi: 10.1111/jnc.15323.
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  21. ARBER C, Alatza A, Leckey CA, Paterson RW, et al
    Mass spectrometry analysis of tau and amyloid-beta in iPSC-derived models of Alzheimer's disease and dementia.
    J Neurochem. 2021 Feb 4. doi: 10.1111/jnc.15315.
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    January 2021
  22. HUANG SJ, Ma YH, Bi YL, Shen XN, et al
    Metabolically healthy obesity and lipids may be protective factors for pathological changes of Alzheimer's disease in cognitively normal adults.
    J Neurochem. 2021 Jan 18. doi: 10.1111/jnc.15306.
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  23. GRUNDER G, Cumming P
    Serotonin and amyloid deposition: A link between depression and Alzheimer's disease?: An Editorial Highlight on "Pimavanserin, a 5HT2A receptor inverse agonist, rapidly suppresses Abeta production and related pathology in a mouse model of Alzheimer's
    J Neurochem. 2021 Jan 18. doi: 10.1111/jnc.15269.
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  24. HARK TJ, Savas JN
    Using stable isotope labeling to advance our understanding of Alzheimer's disease etiology and pathology.
    J Neurochem. 2021 Jan 12. doi: 10.1111/jnc.15298.
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    December 2020
  25. HIGHET B, Anekal PV, Ryan B, Murray H, et al
    fISHing with immunohistochemistry for housekeeping gene changes in Alzheimer's disease using an automated quantitative analysis workflow.
    J Neurochem. 2020 Dec 25. doi: 10.1111/jnc.15283.
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  26. STOLERO N, Frenkel D
    The Dialog between Neurons and Microglia in Alzheimer's Disease: The Neurotransmitters View.
    J Neurochem. 2020 Dec 12. doi: 10.1111/jnc.15262.
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  27. YUEDE CM, Wallace CE, Davis TA, Gardiner WD, et al
    Pimavanserin, a 5HT2A receptor inverse agonist, rapidly suppresses Abeta production and related pathology in a mouse model of Alzheimer's disease.
    J Neurochem. 2020 Dec 5. doi: 10.1111/jnc.15260.
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    Hippocampal hyperglutamatergic signaling matters: Early targeting glutamate neurotransmission as a preventive strategy in Alzheimer's disease: An Editorial Highlight for "Riluzole attenuates glutamatergic tone and cognitive decline in AbetaPP/PS1 mice
    J Neurochem. 2020 Dec 4. doi: 10.1111/jnc.15238.
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  29. LI W, Wu M, Zhang Y, Wei X, et al
    Intermittent fasting promotes adult hippocampal neuronal differentiation by activating GSK-3beta in 3xTg-AD mice.
    J Neurochem. 2020;155:697-713.
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    November 2020
  30. LI L, Miao M, Chen J, Liu Z, et al
    Role of Tet2 in modulating neuronal morphology and cognition in a mouse model of Alzheimer's disease.
    J Neurochem. 2020 Nov 9. doi: 10.1111/jnc.15234.
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  31. VINKLAROVA L, Schmidt M, Benek O, Kuca K, et al
    Friend or enemy? Review of 17beta-HSD10 and its role in human health or disease.
    J Neurochem. 2020;155:231-249.
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    October 2020
  32. LIMEGROVER CS, LeVine H 3rd, Izzo NJ, Yurko R, et al
    Alzheimer's Protection Effect of A673T Mutation May Be Driven by Lower Abeta Oligomer Binding Affinity.
    J Neurochem. 2020 Oct 6. doi: 10.1111/jnc.15212.
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    September 2020
  33. GAUNITZ S, Tjernberg LO, Schedin-Weiss S
    The N-glycan profile in cortex and hippocampus is altered in Alzheimer s disease.
    J Neurochem. 2020 Sep 28. doi: 10.1111/jnc.15202.
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  34. PENA-BAUTISTA C, Alvarez L, Baquero M, Ferrer I, et al
    Plasma isoprostanoids assessment as Alzheimer Disease progression biomarkers.
    J Neurochem. 2020 Sep 12. doi: 10.1111/jnc.15183.
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  35. PEREIRA JD, Fraga VG, Santos ALM, das Gracas Carvalho M, et al
    Alzheimer's disease and type 2 diabetes mellitus: a systematic review of proteomic studies.
    J Neurochem. 2020 Sep 9. doi: 10.1111/jnc.15166.
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  36. BROSSERON F, Kleemann K, Kolbe CC, Santarelli F, et al
    Interrelations of Alzheimer s disease candidate biomarkers neurogranin, fatty acid binding protein 3 and ferritin to neurodegeneration and neuroinflammation.
    J Neurochem. 2020 Sep 7. doi: 10.1111/jnc.15175.
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  37. PEDRINI S, Chatterjee P, Hone E, Martins RN, et al
    High Density Lipoprotein-related cholesterol metabolism in Alzheimer's Disease.
    J Neurochem. 2020 Sep 5. doi: 10.1111/jnc.15170.
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    August 2020
  38. WANG L, Liu S, Xu J, Watanabe N, et al
    Emodin inhibits Abeta42 aggregation and improves cognitive deficits in Alzheimer's disease transgenic mice.
    J Neurochem. 2020 Aug 16. doi: 10.1111/jnc.15156.
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  39. MOSSER S, Gerber H, Fraering PC
    Identification of truncated C-terminal fragments of the Alzheimer's disease amyloid protein precursor derived from sequential proteolytic pathways.
    J Neurochem. 2020 Aug 5. doi: 10.1111/jnc.15143.
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    July 2020
  40. SIMOES-PIRES EN, Ferreira ST, Linden R
    Roles of glutamate receptors in a novel in vitro model of early, comorbid cerebrovascular and Alzheimer's diseases.
    J Neurochem. 2020 Jul 19. doi: 10.1111/jnc.15129.
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  41. MARTINS TS, Trindade D, Vaz M, Campelo I, et al
    Diagnostic and therapeutic potential of exosomes in Alzheimer's disease.
    J Neurochem. 2020 Jul 3. doi: 10.1111/jnc.15112.
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  42. SATHE G, Albert M, Darrow J, Saito A, et al
    Quantitative proteomic analysis of the frontal cortex in Alzheimer's disease.
    J Neurochem. 2020 Jul 2. doi: 10.1111/jnc.15116.
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  43. GUNN AP, Wong BX, McLean C, Fowler C, et al
    Increased glutaminyl cyclase activity in brain of Alzheimer's disease individuals.
    J Neurochem. 2020 Jul 2. doi: 10.1111/jnc.15114.
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    May 2020
  44. DE FREITAS GB, Lourenco MV, De Felice FG
    Protective actions of exercise-related FNDC5/Irisin in memory and Alzheimer's disease.
    J Neurochem. 2020 May 12. doi: 10.1111/jnc.15039.
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    The lipid component of Alzheimer's disease research: An Editorial Highlight for "Brain region-specific amyloid plaque-associated myelin lipid loss, APOE deposition and disruption of the myelin sheath in familial Alzheimer's disease mice" on https://do
    J Neurochem. 2020 May 6. doi: 10.1111/jnc.15025.
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    April 2020
  46. FONTANA IC, Zimmer AR, Rocha AS, Gosmann G, et al
    Amyloid-beta oligomers in cellular models of Alzheimer's disease.
    J Neurochem. 2020 Apr 22. doi: 10.1111/jnc.15030.
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  47. LI Z, Zhu H, Guo Y, Du X, et al
    Gut microbiota regulate cognitive deficits and amyloid deposition in a model of Alzheimer's disease.
    J Neurochem. 2020 Apr 22. doi: 10.1111/jnc.15031.
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  48. BULLAIN S, Doody R
    What works and what doesn't work in Alzheimer's disease? From interventions on risk factors to anti-amyloid trials.
    J Neurochem. 2020 Apr 11. doi: 10.1111/jnc.15023.
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    March 2020
  49. RAJAEI S, Karima S, Sepasi Tehrani H, Shateri S, et al
    Conformational Change and GTPase Activity of Human Tubulin: A Comparative Study on Alzheimer's Disease and Healthy Brain.
    J Neurochem. 2020 Mar 20. doi: 10.1111/jnc.15009.
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  50. LI S, Selkoe DJ
    A mechanistic hypothesis for the impairment of synaptic plasticity by soluble Ab oligomers from Alzheimer brain.
    J Neurochem. 2020 Mar 17. doi: 10.1111/jnc.15007.
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  51. LI B, Liu J, Gu G, Han X, et al
    Impact of neural stem cell-derived extracellular vesicles on mitochondrial dysfunction, sirtuin 1 level and synaptic deficits in Alzheimer's disease.
    J Neurochem. 2020 Mar 7. doi: 10.1111/jnc.15001.
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  52. KAYA I, Jennische E, Lange S, Baykal AT, et al
    Brain Region Specific Amyloid Plaque Associated Myelin Lipid Loss, APOE Deposition and Disruption of the Myelin Sheath in Familial Alzheimer's Disease Mice.
    J Neurochem. 2020 Mar 5. doi: 10.1111/jnc.14999.
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    February 2020
  53. HIERRO-BUJALANCE C, Del Marco A, Ramos-Rodriguez JJ, Infante-Garcia C, et al
    Cell proliferation and neurogenesis alterations in Alzheimer's disease and diabetes mellitus mixed murine models.
    J Neurochem. 2020 Feb 18. doi: 10.1111/jnc.14987.
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    January 2020
  54. HOU TY, Zhou Y, Zhu LS, Wang X, et al
    Correcting abnormalities in miR-124/PTPN1 signaling rescues tau pathology in Alzheimer's disease.
    J Neurochem. 2020 Jan 17:e14961. doi: 10.1111/jnc.14961.
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    November 2019
  55. IMAMURA O, Arai M, Dateki M, Oishi K, et al
    Donepezil-induced oligodendrocyte differentiation is mediated through estrogen receptors.
    J Neurochem. 2019 Nov 28. doi: 10.1111/jnc.14927.
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    October 2019
  56. MICHNO W, Wehrli P, Meier S, Sehlin D, et al
    Chemical Imaging of Evolving Amyloid Plaque Pathology and Associated Abeta Peptide Aggregation in a Transgenic Mouse Model of Alzheimer's Disease.
    J Neurochem. 2019 Oct 12. doi: 10.1111/jnc.14888.
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    June 2019
  57. NICHOLS MR, St-Pierre MK, Wendeln AC, Makoni NJ, et al
    Inflammatory mechanisms in neurodegeneration.
    J Neurochem. 2019;149:562-581.
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    January 2019
  58. HASCUP ER, Broderick SO, Russell MK, Fang Y, et al
    Diet-induced insulin resistance elevates hippocampal glutamate as well as VGLUT1 and GFAP expression in AbetaPP/PS1 mice.
    J Neurochem. 2019;148:219-237.
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