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Alzheimer's Disease

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Articles published in
PLoS Genet
    September 2021
  1. ZHAN L, Li J, Jew B, Sul JH, et al
    Rare variants in the endocytic pathway are associated with Alzheimer's disease, its related phenotypes, and functional consequences.
    PLoS Genet. 2021;17:e1009772.
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    April 2021
  2. TANG S, Buchman AS, De Jager PL, Bennett DA, et al
    Novel Variance-Component TWAS method for studying complex human diseases with applications to Alzheimer's dementia.
    PLoS Genet. 2021;17:e1009482.
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  3. NACKENOFF AG, Hohman TJ, Neuner SM, Akers CS, et al
    PLD3 is a neuronal lysosomal phospholipase D associated with beta-amyloid plaques and cognitive function in Alzheimer's disease.
    PLoS Genet. 2021;17:e1009406.
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    February 2021
  4. LIU N, Xu J, Liu H, Zhang S, et al
    Hippocampal transcriptome-wide association study and neurobiological pathway analysis for Alzheimer's disease.
    PLoS Genet. 2021;17:e1009363.
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    January 2021
  5. MARQUILLY C, Busto GU, Leger BS, Boulanger A, et al
    Htt is a repressor of Abl activity required for APP-induced axonal growth.
    PLoS Genet. 2021;17:e1009287.
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  6. BAIRD DA, Liu JZ, Zheng J, Sieberts SK, et al
    Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome.
    PLoS Genet. 2021;17:e1009224.
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    July 2020
  7. RATNAKUMAR A, Weinhold N, Mar JC, Riaz N, et al
    Protein-Protein interactions uncover candidate 'core genes' within omnigenic disease networks.
    PLoS Genet. 2020;16:e1008903.
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    June 2020
  8. MILIND N, Preuss C, Haber A, Ananda G, et al
    Transcriptomic stratification of late-onset Alzheimer's cases reveals novel genetic modifiers of disease pathology.
    PLoS Genet. 2020;16:e1008775.
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    February 2020
  9. RAMDHANI S, Navarro E, Udine E, Efthymiou AG, et al
    Tensor decomposition of stimulated monocyte and macrophage gene expression profiles identifies neurodegenerative disease-specific trans-eQTLs.
    PLoS Genet. 2020;16:e1008549.
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    May 2019
  10. ONOS KD, Uyar A, Keezer KJ, Jackson HM, et al
    Enhancing face validity of mouse models of Alzheimer's disease with natural genetic variation.
    PLoS Genet. 2019;15:e1008155.
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    December 2018
  11. RAJABLI F, Feliciano BE, Celis K, Hamilton-Nelson KL, et al
    Ancestral origin of ApoE epsilon4 Alzheimer disease risk in Puerto Rican and African American populations.
    PLoS Genet. 2018;14:e1007791.
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    November 2018
  12. RATHORE N, Ramani SR, Pantua H, Payandeh J, et al
    Paired Immunoglobulin-like Type 2 Receptor Alpha G78R variant alters ligand binding and confers protection to Alzheimer's disease.
    PLoS Genet. 2018;14:e1007427.
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    April 2018
  13. LANCOUR D, Naj A, Mayeux R, Haines JL, et al
    One for all and all for One: Improving replication of genetic studies through network diffusion.
    PLoS Genet. 2018;14:e1007306.
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    November 2017
  14. FERNANDEZ MV, Kim JH, Budde JP, Black K, et al
    Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease.
    PLoS Genet. 2017;13:e1007045.
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    August 2017
  15. ROCCHI A, Yamamoto S, Ting T, Fan Y, et al
    A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease.
    PLoS Genet. 2017;13:e1006962.
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    July 2017
  16. LU Q, Powles RL, Abdallah S, Ou D, et al
    Systematic tissue-specific functional annotation of the human genome highlights immune-related DNA elements for late-onset Alzheimer's disease.
    PLoS Genet. 2017;13:e1006933.
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  17. KIM E, Sakata K, Liao FF
    Bidirectional interplay of HSF1 degradation and UPR activation promotes tau hyperphosphorylation.
    PLoS Genet. 2017;13:e1006849.
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    March 2017
  18. KERR F, Sofola-Adesakin O, Ivanov DK, Gatliff J, et al
    Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer's disease.
    PLoS Genet. 2017;13:e1006593.
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    November 2016

  19. Correction: Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease.
    PLoS Genet. 2016;12:e1006456.
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    October 2016
  20. JAKOBSDOTTIR J, van der Lee SJ, Bis JC, Chouraki V, et al
    Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease.
    PLoS Genet. 2016;12:e1006327.
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