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Articles published in
Brain
    March 2026
  1. WEISE CM, Abu-Rumeileh S, Otto M
    From 'senile dementia' to non-vascular Alzheimer's synucleinopathy: the evolution of dementia classification.
    Brain. 2026 Mar 16:awag103. doi: 10.1093.
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  2. LEE J, Cho Y, Choi BY, Kim HK, et al
    HDAC6 regulates BACE1 stability and NLRP3 inflammasome activation in Alzheimer's disease.
    Brain. 2026 Mar 6:awag089. doi: 10.1093.
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    February 2026
  3. KALARIA RN
    The rise and rise of vascular dysfunction in Alzheimer's disease.
    Brain. 2026 Feb 25:awag076. doi: 10.1093.
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  4. LAGARTOS-DONATE MJ, Escobar-Doncel B, Zhang SQ, Pan JP, et al
    Loss of REST associated with Alzheimer's disease pathology is ameliorated by NAD.
    Brain. 2026 Feb 19:awaf261. doi: 10.1093.
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    January 2026
  5. MEHTA RI, Wang T, Leurgans SE, Bennett DA, et al
    Cerebral amyloid angiopathy and Alzheimer's and related pathologies across APOE genotypes.
    Brain. 2026 Jan 22:awag025. doi: 10.1093.
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  6. TRUDEL L, Therriault J, Macedo AC, Hosseini SA, et al
    Clinical-biological Alzheimer's disease stage concordance: insights from cohorts and autopsy data.
    Brain. 2026 Jan 20:awag018. doi: 10.1093.
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  7. YANG T, Zhang D, Huang H, Liu F, et al
    Astrocytic mGluR5-dependent calcium hyperactivity promotes amyloid-beta pathology and cognitive impairment.
    Brain. 2026;149:134-149.
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    December 2025
  8. ZU J, Li C, Cui M, Liu X, et al
    Pioglitazone attenuates complement-mediated microglial synaptic engulfment in an Alzheimer's disease model.
    Brain. 2025 Dec 15:awaf462. doi: 10.1093.
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    November 2025
  9. PINI L, Allali G, Imbimbo BP, Germani M, et al
    Brain connectivity as a new target for Alzheimer's disease therapy?
    Brain. 2025 Nov 28:awaf404. doi: 10.1093.
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  10. KIM B, Yuk M, Park M, Ryu H, et al
    CRISPR editing of miR-33 restores ApoE lipidation and amyloid-beta metabolism in ApoE4 sporadic Alzheimer's disease.
    Brain. 2025 Nov 25:awaf244. doi: 10.1093.
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  11. ZAMMIT MD, Bruzzone H, Cody KA, Morse J, et al
    The tau biomarker cascade is condensed in Down syndrome compared to sporadic Alzheimer's disease.
    Brain. 2025 Nov 15:awaf428. doi: 10.1093.
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  12. LUAN Y, Huang Q, Wang J, Guan Y, et al
    Synaptic density and tau pathology in Alzheimer's disease: a dual role in susceptibility and degeneration.
    Brain. 2025 Nov 13:awaf425. doi: 10.1093.
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  13. LI LL, Wang RZ, Wang Z, Hu H, et al
    Safety and short-term outcomes of lecanemab for Alzheimer's disease in China: a multicentre study.
    Brain. 2025 Nov 11:awaf427. doi: 10.1093.
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  14. WESSELING A, Calandri IL, Bouwman MMA, Reijner N, et al
    Amygdalar and hippocampal volume loss in limbic-predominant age-related TDP-43 encephalopathy.
    Brain. 2025;148:3913-3923.
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  15. RAKET LL, Pichet Binette A, Mattsson-Carlgren N, Janelidze S, et al
    Estimating the time course of biomarker changes in Alzheimer's disease.
    Brain. 2025 Nov 3:awaf413. doi: 10.1093.
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    October 2025
  16. NEITZEL J
    White matter changes in Alzheimer's disease: contributor, consequence or co-pathology?
    Brain. 2025 Oct 30:awaf415. doi: 10.1093.
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  17. ASBY DJ, Fisher RA, Jackson J, Love S, et al
    Post-mortem evidence of pathogenic angiogenesis and abnormal vascular function in early Alzheimer's disease.
    Brain. 2025 Oct 22:awaf394. doi: 10.1093.
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  18. MORRIS LA, Suzuki H, Lee S, Jin Z, et al
    Apathy, effort-based decisions and brain integrity in Alzheimer's and Parkinson's diseases.
    Brain. 2025 Oct 17:awaf393. doi: 10.1093.
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  19. RUIZ-REIG N, Virosztek M, Chehade G, Suelves N, et al
    KIF2A downregulation links amyloid-beta to Tau phosphorylation in Alzheimer's disease.
    Brain. 2025 Oct 10:awaf382. doi: 10.1093.
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  20. ALEXANDERSEN CG, Bassett DS, Goriely A, Chaggar P, et al
    Neuronal activity and amyloid-beta promote tau seeding in the entorhinal cortex in Alzheimer's disease.
    Brain. 2025 Oct 7:awaf374. doi: 10.1093.
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  21. KARLSSON L, Janelidze S, Barthelemy NR, Horie K, et al
    Reference proteins to improve Core 1 and Core 2 Alzheimer's disease CSF and plasma biomarkers.
    Brain. 2025 Oct 6:awaf375. doi: 10.1093.
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  22. VERBERK IMW, van Harten AC, van der Flier WM
    Opposing views or like-minded? International Working Group and Alzheimer's Association criteria.
    Brain. 2025 Oct 1:awaf366. doi: 10.1093.
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    September 2025
  23. JOHNSON DR, Wiste HJ, Lowe V, Schwarz CG, et al
    Staging Alzheimer's disease through amyloid and tau PET.
    Brain. 2025 Sep 19:awaf346. doi: 10.1093.
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  24. PESCOLLER J, Dewenter A, Dehsarvi A, Steward A, et al
    Cortical tau deposition promotes atrophy in connected white matter regions in Alzheimer's disease.
    Brain. 2025 Sep 12:awaf339. doi: 10.1093.
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  25. YU L, Du L, Wang T, Barnes LL, et al
    Neuropathologic correlates of distinct plasma biomarker profiles in community-living older adults.
    Brain. 2025;148:3340-3349.
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    August 2025
  26. DE BRUIN H, Groot C, Barthel H, Bischof GN, et al
    Connectivity as a universal predictor of tau progression in atypical Alzheimer's disease.
    Brain. 2025 Aug 14:awaf279. doi: 10.1093.
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  27. SKELLY D, Attfield KE, Fugger L
    T cells turn in Alzheimer's disease.
    Brain. 2025 Aug 14:awaf288. doi: 10.1093.
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  28. ESPAY AJ, Ezzat K, Kepp KP, Daly T, et al
    Restoring amyloid-beta42 and gamma-secretase function in Alzheimer's disease.
    Brain. 2025 Aug 8:awaf294. doi: 10.1093.
    >> Share

  29. M'BRA PEH, Hamilton LK, Moquin-Beaudry G, Mangahas CL, et al
    Medium-chain triglycerides improve cognition and systemic metabolism in mouse models of Alzheimer's disease.
    Brain. 2025 Aug 6:awaf267. doi: 10.1093.
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  30. BERSON E, Perna A, Bukhari S, Kim Y, et al
    Deep learning-based cell type profiles reveal signatures of Alzheimer's disease resilience and resistance.
    Brain. 2025 Aug 5:awaf285. doi: 10.1093.
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  31. SAADMAAN G, Dalmasso MC, Maria M, Lehtisalo J, et al
    Alzheimer and cardiovascular genetic scores and cognition: the FINGER randomized controlled trial.
    Brain. 2025 Aug 1:awaf277. doi: 10.1093.
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  32. ZUO M, Chang L, Neale N, Maameri L, et al
    The relationship between kidney health and neurodegenerative diseases.
    Brain. 2025;148:2616-2630.
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    July 2025
  33. HAMID M, Detroja TS, Tripathy SJ, Menon V, et al
    Sleep, pericyte subtypes and cognitive decline in adults with and without Alzheimer's disease.
    Brain. 2025 Jul 14:awaf161. doi: 10.1093.
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  34. ANAND C, Abdelnour F, Sipes B, Ma D, et al
    Selective vulnerability and resilience to Alzheimer's disease tauopathy as a function of genes and the connectome.
    Brain. 2025 Jul 9:awaf179. doi: 10.1093.
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  35. WEIL RS
    Seeing the trees in the wood: the importance of co-pathologies in Alzheimer's disease and dementia with Lewy bodies.
    Brain. 2025;148:2233-2234.
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  36. WOODWORTH DC, Lou JJ, Yong WH, Head E, et al
    Common neuropathologic change drivers of hippocampal sclerosis of ageing.
    Brain. 2025;148:2400-2411.
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  37. CHEN J, Li Q, Ji B, Zhang K, et al
    Single-nucleus transcriptome atlas of the basal forebrain reveals diverse ageing-related pathways.
    Brain. 2025;148:2493-2508.
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  38. SILVA-RODRIGUEZ J, Labrador-Espinosa MA, Zhang L, Castro-Labrador S, et al
    The effect of Lewy body (co-)pathology on the clinical and imaging phenotype of amnestic patients.
    Brain. 2025;148:2441-2452.
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  39. ZAWAR I, Luniewski A, Gundlapalli R, Manning C, et al
    The association of seizure control with neuropathology in dementia.
    Brain. 2025;148:2469-2480.
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  40. CICOGNOLA C, Salvado G, Smith R, Palmqvist S, et al
    APOE4 impact on soluble and insoluble tau pathology is mostly influenced by amyloid-beta.
    Brain. 2025;148:2373-2383.
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  41. GRAHAM NSN, Zimmerman KA, Hain J, Rooney E, et al
    Biomarker evidence of neurodegeneration in mid-life former rugby players.
    Brain. 2025 Jul 3:awaf152. doi: 10.1093.
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    June 2025
  42. SCARMEAS N, Noriega De La Colina A
    The duality of disease: the Alzheimer's disease dilemma through the lens of nosos and asthenia.
    Brain. 2025 Jun 26:awaf239. doi: 10.1093.
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  43. JIANG S, Srikanth M, Serpe R, Yavari S, et al
    Early proteasome downregulation and dysfunction drive proteostasis failure in Alzheimer's disease.
    Brain. 2025 Jun 9:awaf222. doi: 10.1093.
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  44. VELLONE D, Leon R, Goodarzi Z, Forkert ND, et al
    Mild behavioural impairment-apathy and core Alzheimer's disease cerebrospinal fluid biomarkers.
    Brain. 2025 Jun 2:awaf194. doi: 10.1093.
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    May 2025
  45. ABDEL-HALEEM AM, Casavant E, Toth B, Teng E, et al
    CSF proteomics of semorinemab Alzheimer's disease trials identifies cell-type specific signatures.
    Brain. 2025 May 28:awaf200. doi: 10.1093.
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  46. WISSE LEM, La Joie R
    Medial temporal lobe structural changes when Down syndrome and Alzheimer's disease collide.
    Brain. 2025 May 14:awaf176. doi: 10.1093.
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  47. RICKENBACH C, Mallone A, Hausle L, Frei L, et al
    Altered T-cell reactivity in the early stages of Alzheimer's disease.
    Brain. 2025 May 5:awaf167. doi: 10.1093.
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    April 2025
  48. POMARA N, Imbimbo BP
    Making a diagnosis of Alzheimer's disease in asymptomatic individuals with positive biomarkers.
    Brain. 2025 Apr 28:awaf162. doi: 10.1093.
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  49. SHARIF SF, Guan DX, Bodnar T, Joseph JT, et al
    Neuropsychiatric symptoms and progression to pathologically confirmed Alzheimer's disease.
    Brain. 2025 Apr 25:awaf156. doi: 10.1093.
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  50. ABANTO JT, Dwivedi AK, Imbimbo BP, Espay AJ, et al
    CSF amyloid-beta40 levels are not associated with efficacy outcomes in Alzheimer's disease trials.
    Brain. 2025 Apr 19:awaf143. doi: 10.1093.
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  51. BUEHNER BJ, Morcillo-Nieto AO, Zsadanyi SE, Rozalem Aranha M, et al
    Medial temporal lobe atrophy in Down syndrome along the Alzheimer's disease continuum.
    Brain. 2025 Apr 17:awaf133. doi: 10.1093.
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  52. LU K, Baker J, Nicholas JM, Street RE, et al
    Associations between accelerated forgetting, amyloid deposition and brain atrophy in older adults.
    Brain. 2025;148:1302-1315.
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    March 2025
  53. ZITSER J, Forner S, Wong K, Chengshi J, et al
    Neuropsychiatric symptoms in sporadic Creutzfeldt-Jakob disease.
    Brain. 2025 Mar 28:awaf077. doi: 10.1093.
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  54. PHILLIPS JM, Dumitrescu LC, Archer DB, Regelson AN, et al
    Novel modelling approaches to elucidate the genetic architecture of resilience to Alzheimer's disease.
    Brain. 2025 Mar 20:awaf106. doi: 10.1093.
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    February 2025

  55. Correction to: Plasma p-tau217 in Alzheimer's disease: Lumipulse and ALZpath SIMOA head-to-head comparison.
    Brain. 2025 Feb 6:awaf034. doi: 10.1093.
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  56. LIU H, Marsh TW, Shi X, Renton AE, et al
    The landscape of autosomal-dominant Alzheimer's disease: global distribution and age of onset.
    Brain. 2025 Feb 4:awaf038. doi: 10.1093.
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  57. HUSAIN M
    Listening into hippocampal hyperexcitability in Alzheimer's disease.
    Brain. 2025;148:347-348.
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  58. WARMENHOVEN N, Salvado G, Janelidze S, Mattsson-Carlgren N, et al
    A comprehensive head-to-head comparison of key plasma phosphorylated tau 217 biomarker tests.
    Brain. 2025;148:416-431.
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    January 2025
  59. FERNANDEZ ARIAS J, Brum WS, Salvado G, Therriault J, et al
    Plasma phosphorylated tau217 strongly associates with memory deficits in the Alzheimer's disease spectrum.
    Brain. 2025 Jan 29:awaf033. doi: 10.1093.
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  60. CHAUVEAU L, Landeau B, Dautricourt S, Turpin AL, et al
    Anterior-temporal network hyperconnectivity is key to Alzheimer's disease: from ageing to dementia.
    Brain. 2025 Jan 15:awaf008. doi: 10.1093.
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  61. GRAHAM AC, Bellou E, Harwood JC, Yaman U, et al
    Human longevity and Alzheimer's disease variants act via microglia and oligodendrocyte gene networks.
    Brain. 2025 Jan 9:awae339. doi: 10.1093.
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  62. VAN DER FLIER WM, Heneka MT
    Zooming in on brain inflammation in Alzheimer's disease.
    Brain. 2025;148:1-2.
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  63. TIAN F, Wang Y, Qian ZM, Ran S, et al
    Plasma metabolomic signature of healthy lifestyle, structural brain reserve and risk of dementia.
    Brain. 2025;148:143-153.
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    December 2024
  64. PILOTTO A, Quaresima V, Trasciatti C, Tolassi C, et al
    Plasma p-tau217 in Alzheimer's disease: Lumipulse and ALZpath SIMOA head-to-head comparison.
    Brain. 2024 Dec 16:awae368. doi: 10.1093.
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  65. WANG D, Honnorat N, Toledo JB, Li K, et al
    Deep learning reveals pathology-confirmed neuroimaging signatures in Alzheimer's, vascular and Lewy body dementias.
    Brain. 2024 Dec 9:awae388. doi: 10.1093.
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  66. LEE SH, Bae EJ, Perez-Acuna D, Jung MK, et al
    Amyloid-beta-activated microglia can induce compound proteinopathies.
    Brain. 2024;147:4105-4120.
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    November 2024
  67. DUONG MT, Das SR, Khandelwal P, Lyu X, et al
    Hypometabolic mismatch with atrophy and tau pathology in mixed Alzheimer and Lewy body disease.
    Brain. 2024 Nov 22:awae352. doi: 10.1093.
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  68. KOCH G, Altomare D, Benussi A, Brechet L, et al
    The emerging field of non-invasive brain stimulation in Alzheimer's disease.
    Brain. 2024 Nov 20:awae292. doi: 10.1093.
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  69. COLLOBY SJ, McAleese KE, Walker L, Erskine D, et al
    Patterns of tau, amyloid and synuclein pathology in ageing, Alzheimer's disease and synucleinopathies.
    Brain. 2024 Nov 12:awae372. doi: 10.1093.
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  70. PELKMANS W, Gispert JD
    Astroglial reactivity is a key modulator of Alzheimer's disease pathological progression.
    Brain. 2024 Nov 8:awae354. doi: 10.1093.
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  71. MACMULLEN C, Sharma N, Davis RL
    Mitochondrial dynamics and bioenergetics in Alzheimer's induced pluripotent stem cell-derived neurons.
    Brain. 2024 Nov 8:awae364. doi: 10.1093.
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  72. DALY T, Imbimbo BP
    Metformin may reduce Alzheimer's disease risk by increasing soluble amyloid-beta42 levels.
    Brain. 2024 Nov 8:awae367. doi: 10.1093.
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  73. WELIKOVITCH LA, Mate de Gerando A, Khasnavis A, Bhavsar H, et al
    Tau, synapse loss and gliosis progress in an Alzheimer's mouse model after amyloid-beta immunotherapy.
    Brain. 2024 Nov 6:awae345. doi: 10.1093.
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  74. SAKATO Y, Shima A, Terada Y, Takeda K, et al
    Delineating three distinct spatiotemporal patterns of brain atrophy in Parkinson's disease.
    Brain. 2024;147:3702-3713.
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  75. BENJAMIN-ZUKERMAN T, Shimon G, Gaine ME, Dakwar A, et al
    A mutation in the PRKAR1B gene drives pathological mechanisms of neurodegeneration across species.
    Brain. 2024;147:3890-3905.
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    October 2024
  76. KOVACS GG, Katsumata Y, Wu X, Aung KZ, et al
    Amyloid-beta predominant Alzheimer's disease neuropathologic change.
    Brain. 2024 Oct 17:awae325. doi: 10.1093.
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  77. KATSUMI Y, Howe IA, Eckbo R, Wong B, et al
    Default mode network tau predicts future clinical decline in atypical early Alzheimer's disease.
    Brain. 2024 Oct 16:awae327. doi: 10.1093.
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  78. AGRAWAL S, Yu L, Leurgans SE, Kapasi A, et al
    Grey matter ageing-related tau astrogliopathy: associations with brain pathologies and cognitive decline.
    Brain. 2024;147:3501-3512.
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  79. REUS LM, Jansen IE, Tijms BM, Visser PJ, et al
    Connecting dementia risk loci to the CSF proteome identifies pathophysiological leads for dementia.
    Brain. 2024;147:3522-3533.
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    September 2024
  80. ABANTO J, Dwivedi AK, Imbimbo BP, Espay AJ, et al
    Increases in amyloid-beta42 slow cognitive and clinical decline in Alzheimer's disease trials.
    Brain. 2024 Sep 11:awae216. doi: 10.1093.
    >> Share

    August 2024
  81. ZELEK WM, Bevan RJ, Nimmo J, Dewilde M, et al
    Brain-penetrant complement inhibition mitigates neurodegeneration in an Alzheimer's disease mouse model.
    Brain. 2024 Aug 31:awae278. doi: 10.1093.
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  82. SHAHIDEHPOUR RK, Nelson PT, Katsumata Y, Bachstetter AD, et al
    Exploring the link between dystrophic microglia and the spread of Alzheimer's neuropathology.
    Brain. 2024 Aug 5:awae258. doi: 10.1093.
    >> Share

  83. GOMEZ-MURCIA V, Launay A, Carvalho K, Burgard A, et al
    Neuronal A2A receptor exacerbates synapse loss and memory deficits in APP/PS1 mice.
    Brain. 2024;147:2691-2705.
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    July 2024
  84. YANG Y, Chen H, Huang S, Chen H, et al
    BOK-engaged mitophagy alleviates neuropathology in Alzheimer's disease.
    Brain. 2024 Jul 25:awae241. doi: 10.1093.
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  85. MATTSSON-CARLGREN N
    Disentangling genetic risks for development and progression of Alzheimer's disease.
    Brain. 2024 Jul 18:awae237. doi: 10.1093.
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  86. RAMANAN S, Akarca D, Henderson SK, Rouse MA, et al
    The graded multidimensional geometry of phenotypic variation and progression in neurodegenerative syndromes.
    Brain. 2024 Jul 17:awae233. doi: 10.1093.
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  87. APPLETON J, Finn Q, Zanotti-Fregonara P, Yu M, et al
    Brain inflammation co-localizes highly with tau in mild cognitive impairment due to early-onset Alzheimer's disease.
    Brain. 2024 Jul 16:awae234. doi: 10.1093.
    >> Share

  88. CAI H, Zhao T, Pang Y, Fu X, et al
    Systemic inflammatory markers in ageing, Alzheimer's disease and other dementias.
    Brain. 2024 Jul 15:awae230. doi: 10.1093.
    >> Share

  89. BARBA L, Abu-Rumeileh S, Barthel H, Massa F, et al
    Clinical and diagnostic implications of Alzheimer's disease copathology in Lewy body disease.
    Brain. 2024 Jul 11:awae203. doi: 10.1093.
    >> Share

  90. DEVULDER A, Vanderlinden G, Van Langenhoven L, Testelmans D, et al
    Epileptic activity on foramen ovale electrodes is associated with sleep and tau pathology in Alzheimer's disease.
    Brain. 2024 Jul 11:awae231. doi: 10.1093.
    >> Share

  91. HUSAIN M
    The heterogeneity of Alzheimer's disease.
    Brain. 2024;147:2259-2260.
    >> Share

  92. OKKELS N, Grothe MJ, Taylor JP, Hasselbalch SG, et al
    Cholinergic changes in Lewy body disease: implications for presentation, progression and subtypes.
    Brain. 2024;147:2308-2324.
    >> Share

  93. NILSSON J, Pichet Binette A, Palmqvist S, Brum WS, et al
    Cerebrospinal fluid biomarker panel for synaptic dysfunction in a broad spectrum of neurodegenerative diseases.
    Brain. 2024;147:2414-2427.
    >> Share

    June 2024
  94. PERETTI DE, Boccalini C, Ribaldi F, Scheffler M, et al
    Association of glial fibrillary acid protein, Alzheimer's disease pathology and cognitive decline.
    Brain. 2024 Jun 28:awae211. doi: 10.1093.
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  95. Correction to: Microbiota from Alzheimer's patients induce deficits in cognition and hippocampal neurogenesis.
    Brain. 2024 Jun 28:awae208. doi: 10.1093.
    >> Share

  96. OLNEY KC, Rabichow BE, Wojtas AM, DeTure M, et al
    Distinct transcriptional alterations distinguish Lewy body disease from Alzheimer's disease.
    Brain. 2024 Jun 25:awae202. doi: 10.1093.
    >> Share

  97. BALLERINI A, Biagioli N, Carbone C, Chiari A, et al
    Late-onset temporal lobe epilepsy: insights from brain atrophy and Alzheimer's disease biomarkers.
    Brain. 2024 Jun 25:awae207. doi: 10.1093.
    >> Share

  98. COOMANS EM, Ossenkoppele R
    The implications of amyloid-beta pathology: only time will tell.
    Brain. 2024;147:1934-1936.
    >> Share

    May 2024
  99. ALTMANN A, Aksman LM, Oxtoby NP, Young A, et al
    Towards cascading genetic risk in Alzheimer's disease.
    Brain. 2024 May 31:awae176. doi: 10.1093.
    >> Share

  100. CHEN F, Zhao J, Meng F, He F, et al
    The vascular contribution of apolipoprotein E to Alzheimer's disease.
    Brain. 2024 May 15:awae156. doi: 10.1093.
    >> Share

  101. SOCH J, Richter A, Kizilirmak JM, Schutze H, et al
    Single-value brain activity scores reflect both severity and risk across the Alzheimer's continuum.
    Brain. 2024 May 14:awae149. doi: 10.1093.
    >> Share

  102. BLUM D, Levi S
    Targeting excitatory:inhibitory network imbalance in Alzheimer's disease.
    Brain. 2024 May 13:awae146. doi: 10.1093.
    >> Share

  103. SANCHEZ-JUAN P, Valeriano-Lorenzo E, Ruiz-Gonzalez A, Pastor AB, et al
    Serum GFAP levels correlate with astrocyte reactivity, post-mortem brain atrophy and neurofibrillary tangles.
    Brain. 2024;147:1667-1679.
    >> Share

  104. DING F, Sun Q, Long C, Rasmussen RN, et al
    Dysregulation of extracellular potassium distinguishes healthy ageing from neurodegeneration.
    Brain. 2024;147:1726-1739.
    >> Share

    April 2024
  105. CODY KA, Langhough RE, Zammit MD, Clark L, et al
    Characterizing brain tau and cognitive decline along the amyloid timeline in Alzheimer's disease.
    Brain. 2024 Apr 26:awae116. doi: 10.1093.
    >> Share

  106. BARBOUR AJ, Gourmaud S, Lancaster E, Li X, et al
    Seizures exacerbate excitatory: inhibitory imbalance in Alzheimer's disease and 5XFAD mice.
    Brain. 2024 Apr 25:awae126. doi: 10.1093.
    >> Share

  107. BAUMEISTER H, Vogel JW, Insel PS, Kleineidam L, et al
    A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings.
    Brain. 2024 Apr 24:awae118. doi: 10.1093.
    >> Share

  108. LIMBERGER C, Zimmer ER
    Blood GFAP reflects astrocyte reactivity to Alzheimer's pathology in post-mortem brain tissue.
    Brain. 2024 Apr 18:awae104. doi: 10.1093.
    >> Share


  109. Correction to: Disrupted daily activity/rest cycles in relation to daily cortisol rhythms of home-dwelling patients with early Alzheimer's dementia.
    Brain. 2024 Apr 10:awae103. doi: 10.1093.
    >> Share

  110. WANG YT, Therriault J, Servaes S, Tissot C, et al
    Sex-specific modulation of amyloid-beta on tau phosphorylation underlies faster tangle accumulation in females.
    Brain. 2024;147:1497-1510.
    >> Share

  111. TANAKA H, Martinez-Valbuena I, Forrest SL, Couto B, et al
    Distinct involvement of the cranial and spinal nerves in progressive supranuclear palsy.
    Brain. 2024;147:1399-1411.
    >> Share

  112. CORRIVEAU-LECAVALIER N, Barnard LR, Botha H, Graff-Radford J, et al
    Uncovering the distinct macro-scale anatomy of dysexecutive and behavioural degenerative diseases.
    Brain. 2024;147:1483-1496.
    >> Share

    March 2024
  113. HUNG C, Fertan E, Livesey FJ, Klenerman D, et al
    APP antisense oligonucleotides reduce Abeta aggregation and rescue endolysosomal dysfunction in Alzheimer's disease.
    Brain. 2024 Mar 25:awae092. doi: 10.1093.
    >> Share

  114. RODRIGUEZ-RODRIGUEZ P, Arroyo-Garcia LE, Tsagkogianni C, Li L, et al
    A cell autonomous regulator of neuronal excitability modulates tau in Alzheimer's disease vulnerable neurons.
    Brain. 2024 Mar 11:awae051. doi: 10.1093.
    >> Share

  115. RODRIGUEZ-VIEITEZ E, Vannini P, Montal V, Graff C, et al
    Cortical microstructural imaging from diffusion MRI: towards sensitive biomarkers for clinical trials.
    Brain. 2024;147:746-748.
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  116. DE MEYER S, Blujdea ER, Schaeverbeke J, Reinartz M, et al
    Longitudinal associations of serum biomarkers with early cognitive, amyloid and grey matter changes.
    Brain. 2024;147:936-948.
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    February 2024
  117. YANG HS, Yau WW, Carlyle BC, Trombetta BA, et al
    Plasma VEGFA and PGF impact longitudinal tau and cognition in preclinical Alzheimer's disease.
    Brain. 2024 Feb 5:awae034. doi: 10.1093.
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  118. AHMED H, Wang Y, Griffiths WJ, Levey AI, et al
    Brain cholesterol and Alzheimer's disease: challenges and opportunities in probe and drug development.
    Brain. 2024 Feb 1:awae028. doi: 10.1093.
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  119. ALBERT-GASCO H, Smith HL, Alvarez-Castelao B, Swinden D, et al
    Trazodone rescues dysregulated synaptic and mitochondrial nascent proteomes in prion neurodegeneration.
    Brain. 2024;147:649-664.
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    January 2024
  120. KUMAR M, Quittot N, Dujardin S, Schlaffner CN, et al
    Alzheimer proteopathic tau seeds are biochemically a forme fruste of mature paired helical filaments.
    Brain. 2024 Jan 18:awad378. doi: 10.1093.
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  121. KIIANITSA K, Lukes ME, Hayes BJ, Brutman J, et al
    TREM2 variants that cause early dementia and increase Alzheimer's disease risk affect gene splicing.
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  122. HAN Y, Chen K, Zhang B, Yu H, et al
    Maf1 loss regulates spinogenesis and attenuates cognitive impairment in Alzheimer's disease.
    Brain. 2024 Jan 16:awae015. doi: 10.1093.
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  123. QIN C, Chen M, Dong MH, Yang S, et al
    Soluble TREM2 triggers microglial dysfunction in neuromyelitis optica spectrum disorders.
    Brain. 2024;147:163-176.
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    December 2023
  124. SAMANTA S, Akhter F, Roy A, Chen D, et al
    New cyclophilin D inhibitor rescues mitochondrial and cognitive function in Alzheimer's disease.
    Brain. 2023 Dec 26:awad432. doi: 10.1093.
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  125. SPOTORNO N, Strandberg O, Stomrud E, Janelidze S, et al
    Diffusion MRI tracks cortical microstructural changes during the early stages of Alzheimer's disease.
    Brain. 2023 Dec 21:awad428. doi: 10.1093.
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  126. STOUFFER KM, Grande X, Duezel E, Johansson M, et al
    Amidst an amygdala renaissance in Alzheimer's disease.
    Brain. 2023 Dec 18:awad411. doi: 10.1093.
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  127. YUYAMA K, Sun H, Fujii R, Hemmi I, et al
    Extracellular vesicle proteome unveils cathepsin B connection to Alzheimer's disease pathogenesis.
    Brain. 2023 Dec 10:awad361. doi: 10.1093.
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  128. TARUTANI A, Kametani F, Tahira M, Saito Y, et al
    Distinct tau folds initiate templated seeding and alter the post-translational modification profile.
    Brain. 2023;146:4988-4999.
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  129. GUBERT C, Hannan AJ
    Microbial manipulation of memories and minds.
    Brain. 2023;146:4791-4793.
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    November 2023
  130. QUESNEL MJ, Labonte A, Picard C, Zetterberg H, et al
    Insulin-like growth factor binding protein-2 in at-risk adults and autopsy-confirmed Alzheimer brains.
    Brain. 2023 Nov 22:awad398. doi: 10.1093.
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  131. SILVA-RODRIGUEZ J, Labrador-Espinosa MA, Moscoso A, Scholl M, et al
    Characteristics of amnestic patients with hypometabolism patterns suggestive of Lewy body pathology.
    Brain. 2023;146:4520-4531.
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  132. HAMPEL H, Elhage A, Cho M, Apostolova LG, et al
    Amyloid-related imaging abnormalities (ARIA): radiological, biological and clinical characteristics.
    Brain. 2023;146:4414-4424.
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  133. RAMANAN VK, Gebre RK, Graff-Radford J, Hofrenning E, et al
    Genetic risk scores enhance the diagnostic value of plasma biomarkers of brain amyloidosis.
    Brain. 2023;146:4508-4519.
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    October 2023
  134. GRABRUCKER S, Marizzoni M, Silajdzic E, Lopizzo N, et al
    Microbiota from Alzheimer's patients induce deficits in cognition and hippocampal neurogenesis.
    Brain. 2023 Oct 18:awad303. doi: 10.1093.
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  135. TUNOLD JA, Tan MMX, Koga S, Geut H, et al
    Lysosomal polygenic risk is associated with the severity of neuropathology in Lewy body disease.
    Brain. 2023;146:4077-4087.
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  136. KEPP KP, Robakis NK, Hoilund-Carlsen PF, Sensi SL, et al
    The amyloid cascade hypothesis: an updated critical review.
    Brain. 2023;146:3969-3990.
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  137. DU F, Yu Q, Swerdlow RH, Waites CL, et al
    Glucocorticoid-driven mitochondrial damage stimulates Tau pathology.
    Brain. 2023;146:4378-4394.
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    September 2023
  138. COOMANS EM, van Westen D, Pichet Binette A, Strandberg O, et al
    Interactions between vascular burden and amyloid-beta pathology on trajectories of tau accumulation.
    Brain. 2023 Sep 18:awad317. doi: 10.1093.
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  139. HARDY J, Mummery C
    Reply: Lecanemab: turning point, or status quo? An ethics perspective.
    Brain. 2023;146:e73.
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  140. BOCANCEA DI, Svenningsson AL, van Loenhoud AC, Groot C, et al
    Determinants of cognitive and brain resilience to tau pathology: a longitudinal analysis.
    Brain. 2023;146:3719-3734.
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  141. DALY T
    Lecanemab: turning point, or status quo? An ethics perspective.
    Brain. 2023;146:e71-e72.
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  142. COOMANS EM, Tomassen J, Ossenkoppele R, Tijms BM, et al
    Genetically identical twin-pair difference models support the amyloid cascade hypothesis.
    Brain. 2023;146:3735-3746.
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    August 2023
  143. KERAMIDIS I, McAllister BB, Bourbonnais J, Wang F, et al
    Restoring neuronal chloride extrusion reverses cognitive decline linked to Alzheimer's disease mutations.
    Brain. 2023 Aug 8:awad250. doi: 10.1093.
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  144. JUNG Y, Damoiseaux JS
    The potential of blood neurofilament light as a marker of neurodegeneration for Alzheimer's disease.
    Brain. 2023 Aug 4:awad267. doi: 10.1093.
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  145. WUESTEFELD A, Pichet Binette A, Berron D, Spotorno N, et al
    Age-related and amyloid-beta-independent tau deposition and its downstream effects.
    Brain. 2023;146:3192-3205.
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  146. RAHAYEL S, Tremblay C, Vo A, Misic B, et al
    Mitochondrial function-associated genes underlie cortical atrophy in prodromal synucleinopathies.
    Brain. 2023;146:3301-3318.
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  147. MCMILLAN PJ, Benbow SJ, Uhrich R, Saxton A, et al
    Tau-RNA complexes inhibit microtubule polymerization and drive disease-relevant conformation change.
    Brain. 2023;146:3206-3220.
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    July 2023
  148. GARCIA AM, de Leon J, Tee BL, Blasi DE, et al
    Speech and language markers of neurodegeneration: a call for global equity.
    Brain. 2023 Jul 27:awad253. doi: 10.1093.
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  149. AKSMAN LM, Oxtoby NP, Scelsi MA, Wijeratne PA, et al
    A data-driven study of Alzheimer's disease related amyloid and tau pathology progression.
    Brain. 2023 Jul 11:awad232. doi: 10.1093.
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  150. YOUNG AL, Vogel JW, Robinson JL, McMillan CT, et al
    Data-driven neuropathological staging and subtyping of TDP-43 proteinopathies.
    Brain. 2023;146:2975-2988.
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    June 2023

  151. Correction to: Brain-derived tau: a novel blood-based biomarker for Alzheimer's disease-type neurodegeneration.
    Brain. 2023 Jun 27:awad208. doi: 10.1093.
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  152. VAN DER ENDE EL, In 't Veld SGJG, Hanskamp I, van der Lee S, et al
    CSF proteomics in autosomal dominant Alzheimer's disease highlights parallels with sporadic disease.
    Brain. 2023 Jun 22:awad213. doi: 10.1093.
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  153. BANERJEE G, Collinge J, Fox NC, Lashley T, et al
    Clinical considerations in early-onset cerebral amyloid angiopathy.
    Brain. 2023 Jun 6:awad193. doi: 10.1093.
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  154. SCHOONHOVEN DN, Coomans EM, Millan AP, van Nifterick AM, et al
    Tau protein spreads through functionally connected neurons in Alzheimer's disease: a combined MEG/PET study.
    Brain. 2023 Jun 5:awad189. doi: 10.1093.
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  155. Correction: The most valuable player or the tombstone: is tau the correct target to treat Alzheimer's disease?
    Brain. 2023 Jun 1:awad176. doi: 10.1093.
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  156. EDWARDS HM, Wallace CE, Gardiner WD, Doherty BM, et al
    Sex-dependent effects of acute stress on amyloid-beta in male and female mice.
    Brain. 2023;146:2268-2274.
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  157. ROBINSON JL, Xie SX, Baer DR, Suh E, et al
    Pathological combinations in neurodegenerative disease are heterogeneous and disease-associated.
    Brain. 2023;146:2557-2569.
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    May 2023
  158. ZHU M, Xiao B, Xue T, Qin S, et al
    Cdc42GAP deficiency contributes to the Alzheimer's disease phenotype.
    Brain. 2023 May 31:awad184. doi: 10.1093.
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  159. DAS V, Hajduch M
    Randomizing for Alzheimer's disease drug trials should consider the cancer history of participants.
    Brain. 2023 May 27:awad177. doi: 10.1093.
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  160. HARDY J, Mummery C
    Reply: Unblinding in the lecanemab trial in Alzheimer's disease.
    Brain. 2023 May 23:awad201. doi: 10.1093.
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  161. VAN GOOL WA
    Unblinding in the lecanemab trial in Alzheimer's disease.
    Brain. 2023 May 18:awad171. doi: 10.1093.
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  162. KORETSKY MJ, Alvarado C, Makarious MB, Vitale D, et al
    Genetic risk factor clustering within and across neurodegenerative diseases.
    Brain. 2023 May 16:awad161. doi: 10.1093.
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  163. JIANG J, Johnson JCS, Requena-Komuro MC, Benhamou E, et al
    Comprehension of acoustically degraded speech in Alzheimer's disease and primary progressive aphasia.
    Brain. 2023 May 15:awad163. doi: 10.1093.
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  164. YOUNES K, Sha SJ
    The MVP or the tombstone: is tau the correct target to treat Alzheimer's disease?
    Brain. 2023 May 8:awad151. doi: 10.1093.
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    April 2023
  165. GOSSYE H, Van Mossevelde S, Sieben A, Bjerke M, et al
    Patients carrying the mutation p.R406W in MAPT present with non-conforming phenotypic spectrum.
    Brain. 2023;146:1624-1636.
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  166. PONNUSAMY M, Wang S, Yuksel M, Hansen MT, et al
    Loss of forebrain BIN1 attenuates hippocampal pathology and neuroinflammation in a tauopathy model.
    Brain. 2023;146:1561-1579.
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  167. NAM MH, Ko HY, Kim D, Lee S, et al
    Visualizing reactive astrocyte-neuron interaction in Alzheimer's disease using 11C-acetate and 18F-FDG.
    Brain. 2023 Apr 17:awad037. doi: 10.1093.
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  168. MATTSSON-CARLGREN N, Palmqvist S
    The emerging era of staging Alzheimer's disease pathology using plasma biomarkers.
    Brain. 2023 Apr 6:awad112. doi: 10.1093.
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    March 2023

  169. Correction to: Blood-brain barrier opening of the default mode network in Alzheimer's disease with magnetic resonance-guided focused ultrasound.
    Brain. 2023 Mar 22:awad082. doi: 10.1093.
    >> Share

  170. DONADIO V, Incensi A, Rizzo G, Westermark GT, et al
    Phosphorylated alpha-synuclein in skin Schwann cells: a new biomarker for multiple system atrophy.
    Brain. 2023;146:1065-1074.
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  171. GREVE HJ, Dunbar AL, Lombo CG, Ahmed C, et al
    The bidirectional lung brain-axis of amyloid-beta pathology: ozone dysregulates the peri-plaque microenvironment.
    Brain. 2023;146:991-1005.
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    February 2023
  172. JACK CR, Wiste HJ, Algeciras-Schimnich A, Figdore DJ, et al
    Predicting amyloid PET and tau PET stages with plasma biomarkers.
    Brain. 2023 Feb 15:awad042. doi: 10.1093.
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    September 2022
  173. GROOT C, Smith R, Stomrud E, Binette AP, et al
    Phospho-tau with subthreshold tau-PET predicts increased tau accumulation rates in amyloid-positive individuals.
    Brain. 2022 Sep 9. pii: 6695020. doi: 10.1093.
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