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Alzheimer's Disease

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Articles published in
Exp Neurol
    May 2021
  1. ISLA AG, Balleza-Tapia H, Fisahn A
    Efficacy of preclinical pharmacological interventions against alterations of neuronal network oscillations in Alzheimer's disease: A systematic review.
    Exp Neurol. 2021 May 14:113743. doi: 10.1016/j.expneurol.2021.113743.
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  2. ANNADURAI N, De Sanctis JB, Hajduch M, Das V, et al
    Tau secretion and propagation: Perspectives for potential preventive interventions in Alzheimer's disease and other tauopathies.
    Exp Neurol. 2021 May 11:113756. doi: 10.1016/j.expneurol.2021.113756.
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    March 2021
  3. NEVES AF, Camargo C, Premer C, Hare JM, et al
    Intravenous administration of mesenchymal stem cells reduces Tau phosphorylation and inflammation in the 3xTg-AD mouse model of Alzheimer's disease.
    Exp Neurol. 2021 Mar 20:113706. doi: 10.1016/j.expneurol.2021.113706.
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  4. MANSOUR HM, Fawzy HM, El-Khatib AS, Khattab MM, et al
    Lapatinib ditosylate rescues memory impairment in D-galactose/ovariectomized rats: Potential repositioning of an anti-cancer drug for the treatment of Alzheimer's disease.
    Exp Neurol. 2021 Mar 13:113697. doi: 10.1016/j.expneurol.2021.113697.
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    January 2021
  5. NAKANISHI K, Sakakima H, Norimatsu K, Otsuka S, et al
    Effect of low-intensity motor balance and coordination exercise on cognitive functions, hippocampal Abeta deposition, neuronal loss, neuroinflammation, and oxidative stress in a mouse model of Alzheimer's disease.
    Exp Neurol. 2021;337:113590.
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  6. MCKNIGHT I, Hart C, Park IH, Shim JW, et al
    Genes causing congenital hydrocephalus: Their chromosomal characteristics of telomere proximity and DNA compositions.
    Exp Neurol. 2021;335:113523.
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    December 2020
  7. TANAKA T, Hirai S, Hosokawa M, Saito T, et al
    Early-life stress induces the development of Alzheimer's disease pathology via angiopathy.
    Exp Neurol. 2020 Dec 9:113552. doi: 10.1016/j.expneurol.2020.113552.
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  8. CHEN HC, Cao JX, Cai YT, Du HL, et al
    Interaction of human IAPP and Abeta1-42 aggravated the AD-related pathology and impaired the cognition in mice.
    Exp Neurol. 2020;334:113490.
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    May 2020
  9. CHEN C, Xu D, Zhang ZH, Jia SZ, et al
    Cognitive improvement and synaptic deficit attenuation by a multifunctional carbazole-based cyanine in AD mice model through regulation of Ca(2+)/CaMKII/CREB signaling pathway.
    Exp Neurol. 2020;327:113210.
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    April 2020
  10. WEIDLING IW, Swerdlow RH
    Mitochondria in Alzheimer's disease and their potential role in Alzheimer's proteostasis.
    Exp Neurol. 2020;330:113321.
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    March 2020
  11. ECKERT GP, Eckert SH, Eckmann J, Hagl S, et al
    Olesoxime improves cerebral mitochondrial dysfunction and enhances Abeta levels in preclinical models of Alzheimer's disease.
    Exp Neurol. 2020 Mar 18:113286. doi: 10.1016/j.expneurol.2020.113286.
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    February 2020
  12. VICENTE MC, Humphrey CM, Gargaglioni LH, Ostrowski TD, et al
    Decreased excitability of locus coeruleus neurons during hypercapnia is exaggerated in the streptozotocin-model of Alzheimer's disease.
    Exp Neurol. 2020 Feb 20:113250. doi: 10.1016/j.expneurol.2020.113250.
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  13. GREWAL R, Reutzel M, Dilberger B, Hein H, et al
    Purified oleocanthal and ligstroside protect against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing.
    Exp Neurol. 2020 Feb 18:113248. doi: 10.1016/j.expneurol.2020.113248.
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  14. LIU B, Liu J, Wang JG, Liu CL, et al
    AdipoRon improves cognitive dysfunction of Alzheimer's disease and rescues impaired neural stem cell proliferation through AdipoR1/AMPK pathway.
    Exp Neurol. 2020 Feb 15:113249. doi: 10.1016/j.expneurol.2020.113249.
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    November 2019
  15. WU GD, Li ZH, Li X, Zheng T, et al
    microRNA-592 blockade inhibits oxidative stress injury in Alzheimer's disease astrocytes via the KIAA0319-mediated Keap1/Nrf2/ARE signaling pathway.
    Exp Neurol. 2019 Nov 21:113128. doi: 10.1016/j.expneurol.2019.113128.
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  16. MUNSTER Y, Keyvani K, Herring A
    Inhibition of excessive kallikrein-8 improves neuroplasticity in Alzheimer's disease mouse model.
    Exp Neurol. 2019 Nov 14:113115. doi: 10.1016/j.expneurol.2019.113115.
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  17. BOESE AC, Hamblin MH, Lee JP
    Neural stem cell therapy for neurovascular injury in Alzheimer's disease.
    Exp Neurol. 2019 Nov 12:113112. doi: 10.1016/j.expneurol.2019.113112.
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    August 2019
  18. GRILLO CA, Woodruff JL, Macht VA, Reagan LP, et al
    Insulin resistance and hippocampal dysfunction: Disentangling peripheral and brain causes from consequences.
    Exp Neurol. 2019;318:71-77.
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    July 2019
  19. NUZZO T, Feligioni M, Cristino L, Pagano I, et al
    Free d-aspartate triggers NMDA receptor-dependent cell death in primary cortical neurons and perturbs JNK activation, Tau phosphorylation, and protein SUMOylation in the cerebral cortex of mice lacking d-aspartate oxidase activity.
    Exp Neurol. 2019;317:51-65.
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    May 2019
  20. XIANG XJ, Song L, Deng XJ, Tang Y, et al
    Mitochondrial methionine sulfoxide reductase B2 links oxidative stress to Alzheimer's disease-like pathology.
    Exp Neurol. 2019 May 9. pii: S0014-4886(19)30097.
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    March 2019
  21. DE SILVA NML, Goncalves RA, Boehnke SE, Forny-Germano L, et al
    Understanding the link between insulin resistance and Alzheimer's disease: Insights from animal models.
    Exp Neurol. 2019 Mar 28. pii: S0014-4886(18)30704.
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    December 2018
  22. FRAZIER HN, Ghoweri AO, Anderson KL, Lin RL, et al
    Broadening the definition of brain insulin resistance in aging and Alzheimer's disease.
    Exp Neurol. 2018;313:79-87.
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    October 2018
  23. BROWN AG, Thapa M, Hooker JW 4th, Ostrowski TD, et al
    Impaired chemoreflex correlates with decreased c-Fos in respiratory brainstem centers of the streptozotocin-induced Alzheimer's disease rat model.
    Exp Neurol. 2018 Oct 22. pii: S0014-4886(18)30285.
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    September 2018
  24. LU MH, Ji WL, Xu DE, Yao PP, et al
    Inhibition of sphingomyelin synthase 1 ameliorates alzheimer-like pathology in APP/PS1 transgenic mice through promoting lysosomal degradation of BACE1.
    Exp Neurol. 2018 Sep 19. pii: S0014-4886(18)30490.
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  25. CASSANO T, Magini A, Giovagnoli S, Polchi A, et al
    Early intrathecal infusion of everolimus restores cognitive function and mood in a murine model of Alzheimer's disease.
    Exp Neurol. 2018 Sep 19. pii: S0014-4886(18)30489.
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    August 2018
  26. POLIS B, Gil-Henn H
    Commentary on Giralt et al.: PTK2B/Pyk2 overexpression improves a mouse model of Alzheimer's disease.
    Exp Neurol. 2018 Aug 29. pii: S0014-4886(18)30398.
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  27. WALKER DG, Tang TM, Lue LF
    Increased expression of toll-like receptor 3, an anti-viral signaling molecule, and related genes in alzheimer's disease brains.
    Exp Neurol. 2018 Aug 1. pii: S0014-4886(18)30279.
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    June 2018
  28. HESSE R, von Einem B, Wagner F, Bott P, et al
    sAPPbeta and sAPPalpha increase structural complexity and E/I input ratio in primary hippocampal neurons and alter Ca(2+) homeostasis and CREB1-signaling.
    Exp Neurol. 2018;304:1-13.
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    May 2018
  29. GIRALT A, de Pins B, Cifuentes-Diaz C, Lopez-Molina L, et al
    PTK2B/Pyk2 overexpression improves a mouse model of Alzheimer's disease.
    Exp Neurol. 2018 May 24. pii: S0014-4886(18)30160.
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    April 2018
  30. TANG Y, Min Z, Xiang XJ, Liu L, et al
    Estrogen-related receptor alpha is involved in Alzheimer's disease-like pathology.
    Exp Neurol. 2018 Apr 8. pii: S0014-4886(18)30087.
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    March 2018
  31. CHENG WH, Stukas S, Martens KM, Namjoshi DR, et al
    Age at injury and genotype modify acute inflammatory and neurofilament-light responses to mild CHIMERA traumatic brain injury in wild-type and APP/PS1 mice.
    Exp Neurol. 2018;301.
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    November 2017
  32. KANTARCI A, Aytan N, Palaska I, Stephens D, et al
    Combined administration of resolvin E1 and lipoxin A4 resolves inflammation in a murine model of Alzheimer's disease.
    Exp Neurol. 2017;300:111-120.
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    July 2017
  33. JIN N, Zhu H, Liang X, Huang W, et al
    Sodium selenate activated Wnt/beta-catenin signaling and repressed amyloid-beta formation in a triple transgenic mouse model of Alzheimer's disease.
    Exp Neurol. 2017 Jul 12. pii: S0014-4886(17)30180.
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    May 2017
  34. HSU WJ, Wildburger N, Haidacher SJ, Nenov MN, et al
    PPARgamma agonists rescue increased phosphorylation of FGF14 at S226 in the Tg2576 mouse model of Alzheimer's disease.
    Exp Neurol. 2017 May 15. pii: S0014-4886(17)30122.
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    February 2017
  35. LOURENCO CF, Ledo A, Barbosa RM, Laranjinha J, et al
    Neurovascular uncoupling in the triple transgenic model of Alzheimer's disease: Impaired cerebral blood flow response to neuronal-derived nitric oxide signaling.
    Exp Neurol. 2017;291:36-43.
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    November 2016
  36. KOO JH, Kang EB, Oh YS, Yang DS, et al
    Treadmill exercise decreases amyloid-beta burden possibly via activation of SIRT-1 signaling in a mouse model of Alzheimer's disease.
    Exp Neurol. 2016;288:142-152.
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    July 2016
  37. MARIN MA, Ziburkus J, Jankowsky J, Rasband MN, et al
    Amyloid-beta plaques disrupt axon initial segments.
    Exp Neurol. 2016;281:93-8.
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    June 2016
  38. DIBATTISTA AM, Dumanis SB, Newman J, Rebeck GW, et al
    Identification and modification of amyloid-independent phenotypes of APOE4 mice.
    Exp Neurol. 2016;280:97-105.
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