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Exp Neurol
    August 2025
  1. KAYE S, Gold A, Lin D, Chen M, et al
    Hypercholesterolemia drives microglial dysfunction and weakens response to amyloid plaques.
    Exp Neurol. 2025;390:115272.
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    July 2025
  2. ALVES RL, Goncalves A, Voytyuk I, Harrison DC, et al
    Behaviour profile characterization of PS19 and rTg4510 tauopathy mouse models: A systematic review and a meta-analysis.
    Exp Neurol. 2025;389:115234.
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    June 2025
  3. PENG XQ, Guo HS, Zhang X, Wu XY, et al
    TREM2 promotes hippocampal neurogenesis through regulating microglial M2 polarization in APP/PS1 mice.
    Exp Neurol. 2025;388:115205.
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    May 2025
  4. VIJAYAN V, Siddique IA, Gupta S, Chopra EM, et al
    Osteocalcin modulates Abeta42 aggregation to aid in amyloid reduction in mouse models of Alzheimer's disease.
    Exp Neurol. 2025 May 27:115322. doi: 10.1016/j.expneurol.2025.115322.
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  5. HE Q, Jiang L, Chao FL, Zhou CN, et al
    The role of LINGO-1 in regulating CB1R/TrkB signalling and GABAergic interneurons in Alzheimer's disease pathogenesis.
    Exp Neurol. 2025 May 27:115319. doi: 10.1016/j.expneurol.2025.115319.
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    April 2025
  6. SIM AY, Kim JY, Lee YH, Lee JE, et al
    Neuroprotective roles of SGLT2 and DPP4 inhibitors: Modulating ketone metabolism and suppressing NLRP3 inflammasome in T2D induced Alzheimer's disease.
    Exp Neurol. 2025 Apr 26:115271. doi: 10.1016/j.expneurol.2025.115271.
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  7. KERR NA, Bramlett HM, Sanchez-Molano J, Higueras AF, et al
    Stool-derived extracellular vesicles increase inflammasome signaling and regulate the gut-brain axis after stroke in Alzheimer's disease transgenic mice.
    Exp Neurol. 2025;390:115269.
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  8. REN J, Wang Y, Wang Y, Zhang Y, et al
    Dynamic changes of hippocampal dendritic spines in Alzheimer's disease mice among the different stages.
    Exp Neurol. 2025 Apr 15:115266. doi: 10.1016/j.expneurol.2025.115266.
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  9. ROZEBOOM A, Broekaart DWM, Anink JJ, Boonkamp L, et al
    Cellular expression of low-density lipoprotein receptor-related protein 1 and amyloid beta deposition in human and rat epileptogenic brain.
    Exp Neurol. 2025;386:115149.
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    March 2025
  10. LIU TT, Yang X, Lei HP, Hu YT, et al
    Gastrodin alleviates Abeta(25-35)-induced glycolytic dysfunction via activating PI3K/AKT/BACH1 signaling in Alzheimer's disease models.
    Exp Neurol. 2025 Mar 22:115225. doi: 10.1016/j.expneurol.2025.115225.
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  11. ALTUN S, Ozdemir S, Arslan H, Kiliclioglu M, et al
    Impact of long-term deltamethrin exposure on Alzheimer's-related neurodegeneration in rats.
    Exp Neurol. 2025;388:115223.
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  12. WANG A, Zhang F, Zhang W, Gong J, et al
    PPM1D ameliorates Alzheimer's disease by promoting mitophagy.
    Exp Neurol. 2025 Mar 14:115218. doi: 10.1016/j.expneurol.2025.115218.
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  13. DA SILVA EA, Faber J, Penitente AR, Fernandes J, et al
    Effects of resistance exercise on behavioral and molecular changes in transgenic female mice for Alzheimer's disease in early and advanced stages.
    Exp Neurol. 2025;388:115217.
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    February 2025
  14. CARTER SKR, Tipton RK, Forman CM, Mosher AP, et al
    Glutamate stress in the caudal nucleus tractus solitarii (nTS): Impact on respiratory function and synaptic signaling in an Alzheimer's disease model.
    Exp Neurol. 2025;387:115190.
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  15. RODRIGUEZ-LOPEZ A, Esteban D, Dominguez-Romero AN, Gevorkian G, et al
    Tg-SwDI transgenic mice: A suitable model for Alzheimer's disease and cerebral amyloid angiopathy basic research and preclinical studies.
    Exp Neurol. 2025;387:115189.
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    January 2025
  16. YANG MX, Wang ZR, Zhang YL, Zhang ZN, et al
    Albumin antagonizes Alzheimer's disease-related Tau pathology and enhances cognitive performance by inhibiting aberrant Tau aggregation.
    Exp Neurol. 2025 Jan 19:115155. doi: 10.1016/j.expneurol.2025.115155.
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  17. LIU S, Liu X, Ke M, Wang J, et al
    Sleep fragmentation impairs cognitive function and exacerbates Alzheimer's disease-related pathology in a mouse model by disrupting mitochondrial biogenesis.
    Exp Neurol. 2025;386:115153.
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  18. LI M, Mo Y, Yu Q, Anayyat U, et al
    Rotating magnetic field improves cognitive and memory impairments in APP/PS1 mice by activating autophagy and inhibiting the PI3K/AKT/mTOR signaling pathway.
    Exp Neurol. 2025;383:115029.
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    December 2024
  19. KAUR R, Pandey S, Gupta S, Singh J, et al
    Harnessing the potential of long non-coding RNAs in the pathophysiology of Alzheimer's disease.
    Exp Neurol. 2024;385:115134.
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  20. FRANKLIN Z, Hull C, Delibegovic M, Platt B, et al
    Pharmacological PTP1B inhibition rescues motor learning, neuroinflammation, and hyperglycaemia in a mouse model of Alzheimer's disease.
    Exp Neurol. 2024;385:115115.
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    November 2024
  21. WANG Y, Wu W, Zeng F, Meng X, et al
    The role of kynurenine pathway metabolism mediated by exercise in the microbial-gut-brain axis in Alzheimer's disease.
    Exp Neurol. 2024;384:115070.
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  22. EL-DESOUKY S, Abdel-Halim M, Fathalla RK, Abadi AH, et al
    A novel phosphodiesterase 5 inhibitor, RF26, improves memory impairment and ameliorates tau aggregation and neuroinflammation in the P301S tauopathy mouse model of Alzheimer's disease.
    Exp Neurol. 2024;384:115058.
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  23. MERINO-SERRAIS P, Soria JM, Arrabal CA, Ortigado-Lopez A, et al
    Protein tau phosphorylation in the proline rich region and its implication in the progression of Alzheimer's disease.
    Exp Neurol. 2024 Nov 8:115049. doi: 10.1016/j.expneurol.2024.115049.
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    October 2024
  24. DHIMAN N, Deshwal S, Rishi V, Singhal N, et al
    Zebrafish as a model organism to study sporadic Alzheimer's disease: Behavioural, biochemical and histological validation.
    Exp Neurol. 2024 Oct 25:115034. doi: 10.1016/j.expneurol.2024.115034.
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  25. ZHENG F, Dong T, Chen Y, Wang L, et al
    Border-associated macrophages: From physiology to therapeutic targets in Alzheimer's disease.
    Exp Neurol. 2024;383:115021.
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  26. WANG X, Wang Q, Wang X, Zhao H, et al
    Early intervention using long-term rhythmic pulsed magnetic stimulation alleviates cognitive decline in a 5xFAD mouse model of Alzheimer's disease.
    Exp Neurol. 2024 Oct 15:115002. doi: 10.1016/j.expneurol.2024.115002.
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    September 2024
  27. BALE LK, West SA, Gades NM, Baker DJ, et al
    Gene deletion of Pregnancy-associated Plasma Protein-A (PAPP-A) improves pathology and cognition in an Alzheimer's disease mouse model.
    Exp Neurol. 2024;382:114976.
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    August 2024
  28. YE Y, Fu C, Li Y, Sun J, et al
    Alternate-day fasting improves cognitive and brain energy deficits by promoting ketone metabolism in the 3xTg mouse model of Alzheimer's disease.
    Exp Neurol. 2024 Aug 12:114920. doi: 10.1016/j.expneurol.2024.114920.
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    July 2024
  29. BERETTI F, Gatti M, Ricchi F, Lipani F, et al
    Neurotoxic effects of coronavirus: Potential implications in Alzheimer's onset and progression.
    Exp Neurol. 2024 Jul 30:114908. doi: 10.1016/j.expneurol.2024.114908.
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  30. ZHAO Y, He C, Hu S, Ni H, et al
    Anti-oxidative stress and cognitive improvement of a semi-synthetic isoorientin-based GSK-3beta inhibitor in rat pheochromocytoma cell PC12 and scopolamine-induced AD model mice via AKT/GSK-3beta/Nrf2 pathway.
    Exp Neurol. 2024 Jul 10:114881. doi: 10.1016/j.expneurol.2024.114881.
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  31. LI CL, Zhou GF, Xie XY, Wang L, et al
    STAU1 exhibits a dual function by promoting amyloidogenesis and tau phosphorylation in cultured cells.
    Exp Neurol. 2024;377:114805.
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    May 2024
  32. HUANG XY, Xue LL, Ma RF, Shi JS, et al
    Inhibition of CXCR4: A perspective on miracle fruit seed for Alzheimer's disease treatment.
    Exp Neurol. 2024 May 29:114841. doi: 10.1016/j.expneurol.2024.114841.
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  33. EL-ARABY RE, Wasif K, Johnson R, Tu Q, et al
    Establishment of a novel cellular model for Alzheimer's disease in vitro studies.
    Exp Neurol. 2024 May 22:114820. doi: 10.1016/j.expneurol.2024.114820.
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  34. ZHANG Y, Mu BR, Ran Z, Zhu T, et al
    Pericytes in Alzheimer's disease: Key players and therapeutic targets.
    Exp Neurol. 2024 May 20:114825. doi: 10.1016/j.expneurol.2024.114825.
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  35. BARATI N, Shojaeian A, Ramezani M, Kalhori F, et al
    Investigating the effect of parasites (toxoplasma gondii RH strain, Leishmania major (MRHO/IR/75/ER), and hydatid cyst) antigens on Alzheimer's disease: An in vivo evaluation.
    Exp Neurol. 2024;377:114813.
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    March 2024
  36. ZHUGE F, Zheng L, Pan Y, Ni L, et al
    DPP-4 inhibition by linagliptin ameliorates age-related mild cognitive impairment by regulating microglia polarization in mice.
    Exp Neurol. 2024;373:114689.
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  37. ZUO Y, Liu HT, Lin LB, Yue RZ, et al
    A new metal ion chelator attenuates human tau accumulation-induced neurodegeneration and memory deficits in mice.
    Exp Neurol. 2024;373:114657.
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    February 2024
  38. ESHANI M, Anupam R, Raj SA, Ashish J, et al
    To evaluate the effect of endothelin receptor agonist IRL-1620 alone and in combination with donepezil in modulating neurodegeneration elicited by amyloid-beta in rats.
    Exp Neurol. 2024 Feb 9:114720. doi: 10.1016/j.expneurol.2024.114720.
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    January 2024
  39. XU M, Li J, Xia L, Du Y, et al
    PCSK6 exacerbates Alzheimer's disease pathogenesis by promoting MT5-MMP maturation.
    Exp Neurol. 2024 Jan 10:114688. doi: 10.1016/j.expneurol.2024.114688.
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  40. YUBOLPHAN R, Pratchayasakul W, Koonrungsesomboon N, Chattipakorn N, et al
    Potential links between platelets and amyloid-beta in the pathogenesis of Alzheimer's disease: Evidence from in vitro, in vivo, and clinical studies.
    Exp Neurol. 2024 Jan 9:114683. doi: 10.1016/j.expneurol.2024.114683.
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  41. DEMBY T, Gross PS, Mandelblatt J, Huang JK, et al
    The chemotherapeutic agent doxorubicin induces brain senescence, with modulation by APOE genotype.
    Exp Neurol. 2024;371:114609.
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    September 2023
  42. HOSSEININIA M, Rostami F, Delphi L, Ghasemzadeh Z, et al
    Memory impairment was ameliorated by corticolimbic microinjections of arachidonylcyclopropylamide (ACPA) and miRNA-regulated lentiviral particles in a streptozotocin-induced Alzheimer's rat model.
    Exp Neurol. 2023 Sep 30:114560. doi: 10.1016/j.expneurol.2023.114560.
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  43. UPADHYAY P, Gupta S
    Dual mode of Triphala in the reversal of cognition through gut restoration in antibiotic mediated prolonged dysbiosis condition in 5XFAD mice.
    Exp Neurol. 2023;367:114473.
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    August 2023
  44. TIAN S, Ye T, Cheng X
    The behavioral, pathological and therapeutic features of the triple transgenic Alzheimer's disease (3 x Tg-AD) mouse model strain.
    Exp Neurol. 2023 Aug 17:114505. doi: 10.1016/j.expneurol.2023.114505.
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  45. HOSSAIN SR, Karem H, Jafari Z, Kolb BE, et al
    Early tactile stimulation influences the development of Alzheimer's disease in gestationally stressed APP (NL-G-F) adult offspring (NL-G-F/NL-G-F) mice.
    Exp Neurol. 2023 Aug 1:114498. doi: 10.1016/j.expneurol.2023.114498.
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    June 2023
  46. DU K, Dou Y, Chen K, Zhao Y, et al
    Activation of TRPV4 induces intraneuronal tau hyperphosphorylation via cholesterol accumulation.
    Exp Neurol. 2023;364:114392.
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    May 2023
  47. GHASEMI A, Qaffaripour Z, Tourani M, Saleki K, et al
    The relationship between long non-coding RNAs and Wnt/beta-catenin signaling pathway in the pathogenesis of Alzheimer's disease.
    Exp Neurol. 2023 May 16:114434. doi: 10.1016/j.expneurol.2023.114434.
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  48. WANG YY, Zhou YN, Jiang L, Wang S, et al
    Long-term voluntary exercise inhibited AGE/RAGE and microglial activation and reduced the loss of dendritic spines in the hippocampi of APP/PS1 transgenic mice.
    Exp Neurol. 2023;363:114371.
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    April 2023
  49. JAFARI Z, Afrashteh N, Kolb BE, Mohajerani MH, et al
    Hearing loss and impaired short-term memory in an Alzheimer's disease mouse model of amyloid-beta pathology.
    Exp Neurol. 2023 Apr 17:114413. doi: 10.1016/j.expneurol.2023.114413.
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  50. YANG YY, Ren YT, Jia MY, Bai CY, et al
    The human islet amyloid polypeptide reduces hippocampal tauopathy and behavioral impairments in P301S mice without inducing neurotoxicity or seeding amyloid aggregation.
    Exp Neurol. 2023;362:114346.
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  51. WU SL, Yu B, Cheng YJ, Ren SY, et al
    Brain region-specific myelinogenesis is not directly linked to amyloid-beta in APP/PS1 transgenic mice.
    Exp Neurol. 2023;362:114344.
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  52. LI L, Miao J, Jiang Y, Dai CL, et al
    Passive immunization inhibits tau phosphorylation and improves recognition learning and memory in 3xTg-AD mice.
    Exp Neurol. 2023;362:114337.
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    March 2023
  53. MEI Y, Li Y, Cheng YX, Gao L, et al
    The effect of gastric bypass surgery on cognitive function of Alzheimer's disease and the role of GLP1-SGLT1 pathway.
    Exp Neurol. 2023 Mar 7:114377. doi: 10.1016/j.expneurol.2023.114377.
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  54. WANG C, Chang Y, Zhu J, Wu Y, et al
    AdipoRon mitigates tau pathology and restores mitochondrial dynamics via AMPK-related pathway in a mouse model of Alzheimer's disease.
    Exp Neurol. 2023;363:114355.
    >> Share


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