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Articles published in
Lancet
    December 2025
  1. KEDHI E, Hermanides RS, Dambrink JE, Singh SK, et al
    TransCatheter aortic valve implantation and fractional flow reserve-guided percutaneous coronary intervention versus conventional surgical aortic valve replacement and coronary bypass grafting for treatment of patients with aortic valve stenosis and c
    Lancet. 2025;404:2593-2602.
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    September 2025
  2. FALKENBERG M, James S, Andersson M, Andersson M, et al
    Paclitaxel-coated versus uncoated devices for infrainguinal endovascular revascularisation in chronic limb-threatening ischaemia (SWEDEPAD 1): a multicentre, participant-masked, registry-based, randomised controlled trial.
    Lancet. 2025;406:1103-1114.
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  3. NORDANSTIG J, James S, Andersson M, Andersson M, et al
    Paclitaxel-coated versus uncoated devices for infrainguinal endovascular revascularisation in patients with intermittent claudication (SWEDEPAD 2): a multicentre, participant-masked, registry-based, randomised controlled trial.
    Lancet. 2025;406:1115-1127.
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    August 2025
  4. KIM MC, Ahn JH, Hyun DY, Lim Y, et al
    Immediate versus staged complete revascularisation during index admission in patients with ST-segment elevation myocardial infarction and multivessel disease (OPTION-STEMI): a multicentre, non-inferiority, open-label, randomised trial.
    Lancet. 2025 Aug 28:S0140-6736(25)01529-6. doi: 10.1016/S0140-6736(25)01529.
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  5. VERMA S, Leiter LA, Teoh H, Mancini GBJ, et al
    Effect of evolocumab on saphenous vein graft patency after coronary artery bypass surgery (NEWTON-CABG CardioLink-5): an international, randomised, double-blind, placebo-controlled trial.
    Lancet. 2025 Aug 28:S0140-6736(25)01633-2. doi: 10.1016/S0140-6736(25)01633.
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    March 2025
  6. CHOI KH, Park YH, Lee JY, Jeong JO, et al
    Efficacy and safety of clopidogrel versus aspirin monotherapy in patients at high risk of subsequent cardiovascular event after percutaneous coronary intervention (SMART-CHOICE 3): a randomised, open-label, multicentre trial.
    Lancet. 2025 Mar 28:S0140-6736(25)00449-0. doi: 10.1016/S0140-6736(25)00449.
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  7. KIRTANE AJ, Genereux P, Lewis B, Shlofmitz RA, et al
    Orbital atherectomy versus balloon angioplasty before drug-eluting stent implantation in severely calcified lesions eligible for both treatment strategies (ECLIPSE): a multicentre, open-label, randomised trial.
    Lancet. 2025 Mar 28:S0140-6736(25)00450-7. doi: 10.1016/S0140-6736(25)00450.
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  8. FEARON WF, Zimmermann FM, Ding VY, Takahashi K, et al
    Outcomes after fractional flow reserve-guided percutaneous coronary intervention versus coronary artery bypass grafting (FAME 3): 5-year follow-up of a multicentre, open-label, randomised trial.
    Lancet. 2025 Mar 28:S0140-6736(25)00505-7. doi: 10.1016/S0140-6736(25)00505.
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  9. HU X, Zhang J, Yang S, Jiang J, et al
    Angiography-derived fractional flow reserve versus intravascular ultrasound to guide percutaneous coronary intervention in patients with coronary artery disease (FLAVOUR II): a multicentre, randomised, non-inferiority trial.
    Lancet. 2025 Mar 28:S0140-6736(25)00504-5. doi: 10.1016/S0140-6736(25)00504.
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    February 2025
  10. HILL MD, Goyal M, Demchuk AM, Menon BK, et al
    Efficacy and safety of nerinetide in acute ischaemic stroke in patients undergoing endovascular thrombectomy without previous thrombolysis (ESCAPE-NEXT): a multicentre, double-blind, randomised controlled trial.
    Lancet. 2025;405:560-570.
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  11. LI W, Lan J, Wei M, Liu L, et al
    Normobaric hyperoxia combined with endovascular treatment for acute ischaemic stroke in China (OPENS-2 trial): a multicentre, randomised, single-blind, sham-controlled trial.
    Lancet. 2025;405:486-497.
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    December 2024
  12. NOGUEIRA RG, Jovin TG, Liu X, Hu W, et al
    Endovascular therapy for acute vertebrobasilar occlusion (VERITAS): a systematic review and individual patient data meta-analysis.
    Lancet. 2024 Dec 11:S0140-6736(24)01820-8. doi: 10.1016/S0140-6736(24)01820.
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    November 2024
  13. LIU J, Zhou Y, Zhang L, Li Z, et al
    Balloon guide catheters for endovascular thrombectomy in patients with acute ischaemic stroke due to large-vessel occlusion in China (PROTECT-MT): a multicentre, open-label, blinded-endpoint, randomised controlled trial.
    Lancet. 2024 Nov 20:S0140-6736(24)02315-8. doi: 10.1016/S0140-6736(24)02315.
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    October 2024
  14. ANDERSEN BK, Sejr-Hansen M, Maillard L, Campo G, et al
    Quantitative flow ratio versus fractional flow reserve for coronary revascularisation guidance (FAVOR III Europe): a multicentre, randomised, non-inferiority trial.
    Lancet. 2024 Oct 29:S0140-6736(24)02175-5. doi: 10.1016/S0140-6736(24)02175.
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  15. ERLINGE D, Andersson J, Frobert O, Tornerud M, et al
    Bioadaptor implant versus contemporary drug-eluting stent in percutaneous coronary interventions in Sweden (INFINITY-SWEDEHEART): a single-blind, non-inferiority, registry-based, randomised controlled trial.
    Lancet. 2024 Oct 25:S0140-6736(24)02227-X. doi: 10.1016/S0140-6736(24)02227.
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    September 2024
  16. NGUYEN TN, Abdalkader M, Fischer U, Qiu Z, et al
    Endovascular management of acute stroke.
    Lancet. 2024;404:1265-1278.
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    August 2024
  17. VALGIMIGLI M, Hong SJ, Gragnano F, Chalkou K, et al
    De-escalation to ticagrelor monotherapy versus 12 months of dual antiplatelet therapy in patients with and without acute coronary syndromes: a systematic review and individual patient-level meta-analysis of randomised trials.
    Lancet. 2024 Aug 30:S0140-6736(24)01616-7. doi: 10.1016/S0140-6736(24)01616.
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  18. HONG SJ, Lee SJ, Lee SH, Lee JY, et al
    Optical coherence tomography-guided versus angiography-guided percutaneous coronary intervention for patients with complex lesions (OCCUPI): an investigator-initiated, multicentre, randomised, open-label, superiority trial in South Korea.
    Lancet. 2024 Aug 30:S0140-6736(24)01454-5. doi: 10.1016/S0140-6736(24)01454.
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  19. MAMAS MA, Mintz GS
    Optical coherence tomography imaging for complex percutaneous coronary intervention.
    Lancet. 2024 Aug 30:S0140-6736(24)01593-9. doi: 10.1016/S0140-6736(24)01593.
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  20. GAO C, He X, Ouyang F, Zhang Z, et al
    Drug-coated balloon angioplasty with rescue stenting versus intended stenting for the treatment of patients with de novo coronary artery lesions (REC-CAGEFREE I): an open-label, randomised, non-inferiority trial.
    Lancet. 2024 Aug 30:S0140-6736(24)01594-0. doi: 10.1016/S0140-6736(24)01594.
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  21. MCENTEGART MB, Kirtane AJ
    How feasible is a cage-free solution for de novo coronary artery disease?
    Lancet. 2024 Aug 30:S0140-6736(24)01696-9. doi: 10.1016/S0140-6736(24)01696.
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    May 2024
  22. HILKENS NA, Casolla B, Leung TW, de Leeuw FE, et al
    Stroke.
    Lancet. 2024 May 14:S0140-6736(24)00642-1. doi: 10.1016/S0140-6736(24)00642.
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    April 2024
  23. FOLEY MJ, Rajkumar CA, Ahmed-Jushuf F, Simader FA, et al
    Coronary sinus reducer for the treatment of refractory angina (ORBITA-COSMIC): a randomised, placebo-controlled trial.
    Lancet. 2024;403:1543-1553.
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  24. LI X, Ge Z, Kan J, Anjum M, et al
    Intravascular ultrasound-guided versus angiography-guided percutaneous coronary intervention in acute coronary syndromes (IVUS-ACS): a two-stage, multicentre, randomised trial.
    Lancet. 2024 Apr 5:S0140-6736(24)00282-4. doi: 10.1016/S0140-6736(24)00282.
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  25. DEN DEKKER WK
    Is intravascular imaging the future of percutaneous coronary intervention?
    Lancet. 2024 Apr 5:S0140-6736(24)00430-6. doi: 10.1016/S0140-6736(24)00430.
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  26. GE Z, Kan J, Gao X, Raza A, et al
    Ticagrelor alone versus ticagrelor plus aspirin from month 1 to month 12 after percutaneous coronary intervention in patients with acute coronary syndromes (ULTIMATE-DAPT): a randomised, placebo-controlled, double-blind clinical trial.
    Lancet. 2024 Apr 5:S0140-6736(24)00473-2. doi: 10.1016/S0140-6736(24)00473.
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  27. PARK SJ, Ahn JM, Kang DY, Yun SC, et al
    Preventive percutaneous coronary intervention versus optimal medical therapy alone for the treatment of vulnerable atherosclerotic coronary plaques (PREVENT): a multicentre, open-label, randomised controlled trial.
    Lancet. 2024 Apr 4:S0140-6736(24)00413-6. doi: 10.1016/S0140-6736(24)00413.
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  28. BOROVAC JA
    Percutaneous coronary intervention for non-obstructive vulnerable plaques.
    Lancet. 2024 Apr 4:S0140-6736(24)00488-4. doi: 10.1016/S0140-6736(24)00488.
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    February 2024
  29. LEE ZS, Ryan N
    Intravascular imaging in percutaneous coronary intervention.
    Lancet. 2024 Feb 21:S0140-6736(23)02686-7. doi: 10.1016/S0140-6736(23)02686.
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  30. STONE GW, Christiansen EH, Ali ZA, Andreasen LN, et al
    Intravascular imaging-guided coronary drug-eluting stent implantation: an updated network meta-analysis.
    Lancet. 2024 Feb 21:S0140-6736(23)02454-6. doi: 10.1016/S0140-6736(23)02454.
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  31. CONSOLI A, Gory B
    Long-term results of mechanical thrombectomy for large ischaemic stroke.
    Lancet. 2024 Feb 8:S0140-6736(24)00158-2. doi: 10.1016/S0140-6736(24)00158.
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  32. SARRAJ A, Abraham MG, Hassan AE, Blackburn S, et al
    Endovascular thrombectomy plus medical care versus medical care alone for large ischaemic stroke: 1-year outcomes of the SELECT2 trial.
    Lancet. 2024 Feb 8:S0140-6736(24)00050-3. doi: 10.1016/S0140-6736(24)00050.
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    January 2024
  33. LANDI A, Pedrazzini G, Wild L, Beele A, et al
    Coronary embolisation of native aortic valve debris during transcatheter aortic valve replacement: mechanical embolectomy and histopathological analysis.
    Lancet. 2024;403:e5-e6.
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    December 2023
  34. JIMENEZ DIAZ VA, Iniguez Romo A
    Intracoronary artery visualisation of crystalline sirolimus deposits after drug-coated balloon angioplasty for acute coronary syndrome.
    Lancet. 2023;402:2111-2112.
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    October 2023
  35. IGLESIAS JF, Roffi M, Losdat S, Muller O, et al
    Long-term outcomes with biodegradable polymer sirolimus-eluting stents versus durable polymer everolimus-eluting stents in ST-segment elevation myocardial infarction: 5-year follow-up of the BIOSTEMI randomised superiority trial.
    Lancet. 2023 Oct 25:S0140-6736(23)02197-9. doi: 10.1016/S0140-6736(23)02197.
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  36. BUITEN RA, Ploumen EH
    Drug-eluting stents for ST-segment elevation myocardial infarction: extending the biodegradable versus durable polymer debate.
    Lancet. 2023 Oct 25:S0140-6736(23)02297-3. doi: 10.1016/S0140-6736(23)02297.
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  37. DIPPEL DWJ, Roozenbeek B
    Thrombectomy for acute ischaemic stroke without advanced imaging.
    Lancet. 2023 Oct 10:S0140-6736(23)02229-8. doi: 10.1016/S0140-6736(23)02229.
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  38. BENDSZUS M, Fiehler J, Subtil F, Bonekamp S, et al
    Endovascular thrombectomy for acute ischaemic stroke with established large infarct: multicentre, open-label, randomised trial.
    Lancet. 2023 Oct 10:S0140-6736(23)02032-9. doi: 10.1016/S0140-6736(23)02032.
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    August 2023
  39. HANKEY GJ
    Does thrombolysis add value to thrombectomy for acute ischaemic stroke?
    Lancet. 2023 Aug 25:S0140-6736(23)01202-3. doi: 10.1016/S0140-6736(23)01202.
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