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Ann Intern Med
    November 2025
  1. GANDH AS, Siddu M, Jillella D
    In minor stroke, adding IV thrombolysis to nonthrombolytic usual care does not increase excellent functional outcome at 90 d.
    Ann Intern Med. 2025 Nov 4. doi: 10.7326/ANNALS-25-04399.
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  2. GODOY A, Douketis JD
    In cancer-associated thrombosis, DOACs reduce VTE and increase clinically relevant nonmajor bleeding vs. LMWH at 3 to 12 mo.
    Ann Intern Med. 2025;178:JC127.
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    September 2025
  3. JUNG M, Reisert M, Rieder H, Rospleszcz S, et al
    Association Between Body Composition and Cardiometabolic Outcomes : A Prospective Cohort Study.
    Ann Intern Med. 2025 Sep 30. doi: 10.7326/ANNALS-24-01863.
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  4. KOTANIDIS CP, Gorey S, Marwah H, Pearl A, et al
    Revision of Research Abstracts Through the Editorial Process.
    Ann Intern Med. 2025 Sep 2. doi: 10.7326/ANNALS-25-02250.
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  5. KHAN F, Hill MD
    In carotid stenosis with low or intermediate risk for stroke, adding revascularization to OMT did not improve outcomes at 2 y.
    Ann Intern Med. 2025 Sep 2. doi: 10.7326/ANNALS-25-03078.
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  6. LO BM
    In acute ischemic stroke with large core infarct, EVT improves mRS scores but increases symptomatic intracranial hemorrhage at 90 d.
    Ann Intern Med. 2025 Sep 2. doi: 10.7326/ANNALS-25-03146.
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  7. ALBERTS MJ
    In ischemic stroke prevention, apixaban and aspirin do not differ for intracranial hemorrhage events.
    Ann Intern Med. 2025 Sep 2. doi: 10.7326/ANNALS-25-03295.
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  8. FIELD TS
    In AIS due to LVO presenting within 4.5 h of onset, adding tenecteplase to EVT increased functional independence at 90 d.
    Ann Intern Med. 2025 Sep 2. doi: 10.7326/ANNALS-25-03337.
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    August 2025
  9. SMITH KC, Gaziano TA, Mushlin AI, Cutler DM, et al
    Effect of Systolic Blood Pressure Measurement Error on the Cost-Effectiveness of Intensive Blood Pressure Targets.
    Ann Intern Med. 2025 Aug 19. doi: 10.7326/ANNALS-25-00560.
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  10. FIELD TS
    At 4.5 to 24 h after posterior circulation stroke onset, alteplase vs. standard medical care increased 90-d functional independence.
    Ann Intern Med. 2025 Aug 5. doi: 10.7326/ANNALS-25-02446.
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    July 2025
  11. MONTANE B, Zhang S, Wolfe JD, Prime S, et al
    Catheter and Surgical Ablation for Atrial Fibrillation : A Systematic Review and Meta-analysis.
    Ann Intern Med. 2025 Jul 1. doi: 10.7326/ANNALS-25-00253.
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    June 2025
  12. SAEED A, Mulukutla SR, Thoma F, Lemon L, et al
    Comparison of Semaglutide or Dulaglutide Versus Empagliflozin for Risk for Death and Cardiovascular Outcomes Among Patients With Type 2 Diabetes : Two Target Trial Emulation Studies.
    Ann Intern Med. 2025 Jun 17. doi: 10.7326/ANNALS-24-00775.
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  13. KATSANOS AH, Douketis JD
    In survivors of ICH with AF, DOACs reduced incident ischemic stroke and increased recurrent ICH at a median 1.4 y.
    Ann Intern Med. 2025 Jun 3. doi: 10.7326/ANNALS-25-01772.
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  14. BATUR P
    Some combined and progestin-only contraceptives were linked to increased risk for ischemic stroke and myocardial infarction.
    Ann Intern Med. 2025 Jun 3. doi: 10.7326/ANNALS-25-01774.
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    May 2025
  15. ALBERTS MJ
    In patients with subclinical AF, apixaban vs. aspirin reduced stroke or systemic embolism at 3.5 y in those with previous stroke or TIA.
    Ann Intern Med. 2025 May 6. doi: 10.7326/ANNALS-25-01330.
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  16. LO B
    In ischemic stroke, IV thrombolysis >4.5 h after symptom onset vs. standard medical care improves 90-d functional outcomes.
    Ann Intern Med. 2025 May 6. doi: 10.7326/ANNALS-25-01326.
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  17. MANSOOR H, Elgendy IY
    In AF with recent ACS or PCI, apixaban reduced total bleeding vs. VKA; aspirin increased total bleeding vs. placebo at 6 mo.
    Ann Intern Med. 2025;178:JC57.
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  18. DONATO AA, Rahimian S
    Non-vitamin K oral anticoagulants and aspirin do not differ for major bleeding and intracranial hemorrhage at a mean 20 mo.
    Ann Intern Med. 2025;178:JC58.
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    April 2025
  19. ABDEL-QADIR H, Gunn M, Fang J, Odugbemi T, et al
    Risk for Stroke After Newly Diagnosed Atrial Fibrillation During Hospitalization for Other Primary Diagnoses : A Retrospective Cohort Study.
    Ann Intern Med. 2025 Apr 22. doi: 10.7326/ANNALS-24-01967.
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  20. YNALVEZ LA, Deswal A
    In adults with HF with preserved ejection fraction and obesity, tirzepatide reduced a composite of CV death or worsening HF at 2 y.
    Ann Intern Med. 2025;178:JC43.
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  21. WANG Y, Lip GYH
    In HF with mildly reduced or preserved ejection fraction, finerenone reduced CV death and worsening HF, regardless of baseline LVEF.
    Ann Intern Med. 2025;178:JC44.
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    February 2025
  22. LEE YJ, Gao X, Lee SH, Kan J, et al
    De-escalating Dual Antiplatelet Therapy to Ticagrelor Monotherapy in Acute Coronary Syndrome : A Systemic Review and Individual Patient Data Meta-Analysis of Randomized Clinical Trials.
    Ann Intern Med. 2025 Feb 18. doi: 10.7326/ANNALS-24-03102.
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  23. SMETANA GW, Gelfand EV, Tung P, Burns RB, et al
    How Would You Manage This Patient With Recent-Onset Atrial Fibrillation? Grand Rounds Discussion From Beth Israel Deaconess Medical Center.
    Ann Intern Med. 2025 Feb 11. doi: 10.7326/ANNALS-24-03490.
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  24. SHARMA M, Srivastava A
    In acute ischemic stroke with AF, early DOAC initiation was noninferior to delayed initiation for ischemic and hemorrhagic outcomes at 90 d.
    Ann Intern Med. 2025 Feb 4. doi: 10.7326/ANNALS-24-03879.
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  25. KOROMPOKI E, Douketis JD
    In patients with ESUS, the effects of OAC and antiplatelet therapy on recurrent ischemic stroke differ across subgroups at 1 to 5 y.
    Ann Intern Med. 2025 Feb 4. doi: 10.7326/ANNALS-24-03608.
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  26. RACO MD, Raco DL
    In asymptomatic severe AS, early TAVR vs. clinical surveillance reduced a composite of death, stroke, or CV hospitalization.
    Ann Intern Med. 2025 Feb 4. doi: 10.7326/ANNALS-24-03735.
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    January 2025
  27. EAPEN BC, Tran J, Ballard-Hernandez J, Buelt A, et al
    Stroke Rehabilitation: Synopsis of the 2024 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guidelines.
    Ann Intern Med. 2025 Jan 21. doi: 10.7326/ANNALS-24-02205.
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  28. BATES ER
    In subclinical AF, apixaban vs. aspirin reduced stroke or systemic embolism at 3.5 y, regardless of duration of recent subclinical AF episodes.
    Ann Intern Med. 2025 Jan 7. doi: 10.7326/ANNALS-24-03370.
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  29. MORENO R
    In asymptomatic severe AS, early surgery vs. conservative therapy reduced a composite of death, MI, stroke, or HF hospitalization at 63 mo.
    Ann Intern Med. 2025 Jan 7. doi: 10.7326/ANNALS-24-03367.
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    December 2024
  30. DONATO AA, Goswami V
    In acute ischemic stroke and a large infarct, adding EVT to medical treatment improved functional outcome at 12 mo.
    Ann Intern Med. 2024 Dec 3. doi: 10.7326/ANNALS-24-02886.
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  31. LIBMAN H, Anderson TS, Rangan VV, Reynolds EE, et al
    How Would You Manage This Patient With Gastroesophageal Reflux Symptoms? Grand Rounds Discussion From Beth Israel Deaconess Medical Center.
    Ann Intern Med. 2024;177:1695-1701.
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    November 2024
  32. ROMITI GF, Talerico G
    In subclinical AF, the benefit of apixaban vs. aspirin on stroke or systemic embolism trended higher with CHA(2)DS(2)-VASc >4.
    Ann Intern Med. 2024;177:JC125.
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    October 2024
  33. WOODRUFF RC, Kaholokula JK, Riley L, Tong X, et al
    Cardiovascular Disease Mortality Among Native Hawaiian and Pacific Islander Adults Aged 35 Years or Older, 2018 to 2022.
    Ann Intern Med. 2024 Oct 15. doi: 10.7326/M24-0801.
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  34. SHARMA M, Srivastva A
    In ischemic stroke treated within 4.5 h, reteplase vs. alteplase increased excellent functional outcome at 90 d.
    Ann Intern Med. 2024 Oct 1. doi: 10.7326/ANNALS-24-02228.
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  35. DAVIDSON MB
    In adults with hypertension and high CV risk, intensive vs. standard BP-lowering therapy reduced major vascular events.
    Ann Intern Med. 2024;177:JC111.
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    September 2024
  36. KODUMURI N, Siddu M, Jillella D
    In acute ischemic stroke with a large core infarct, endovascular thrombectomy reduced disability at 90 d.
    Ann Intern Med. 2024 Sep 3. doi: 10.7326/ANNALS-24-01578.
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    August 2024
  37. DUNBAR KB
    Gastroesophageal Reflux Disease.
    Ann Intern Med. 2024;177:ITC113-ITC128.
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  38. CLIFFORD C, Yan AT
    After PCI and 1 mo of DAPT for ACS, ticagrelor alone vs. continued DAPT for 11 mo reduced bleeding without increasing MACCE.
    Ann Intern Med. 2024;177:JC86.
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    July 2024
  39. SIMON TG, Singer DE, Zhang Y, Mastrorilli JM, et al
    Comparative Effectiveness and Safety of Apixaban, Rivaroxaban, and Warfarin in Patients With Cirrhosis and Atrial Fibrillation : A Nationwide Cohort Study.
    Ann Intern Med. 2024 Jul 9. doi: 10.7326/M23-3067.
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  40. BARNES GD
    In device-detected AF, DOACs vs. aspirin or placebo reduce ischemic stroke and increase major bleeding.
    Ann Intern Med. 2024 Jul 2. doi: 10.7326/ANNALS-24-00652.
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    June 2024
  41. SEBASTIAN IA, Hill MD
    In ischemic stroke, adding IV thrombolysis
    Ann Intern Med. 2024 Jun 4. doi: 10.7326/ANNALS-24-00519.
    >> Share

  42. WEITZ HH, Merli GJ, Lip GYH
    Annals Consult Guys - The ABCs of Atrial Fibrillation.
    Ann Intern Med. 2024;177:e2400618CG.
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  43. FIELD TS
    In cryptogenic stroke and atrial cardiopathy, apixaban did not reduce recurrent stroke vs. aspirin.
    Ann Intern Med. 2024;177:JC65.
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  44. CHIA JE, Mukherjee D
    After stent implantation for ACS, ticagrelor monotherapy after <1 mo of DAPT vs. 12 mo of DAPT improved 1-y net clinical benefit.
    Ann Intern Med. 2024;177:JC64.
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    May 2024
  45. XU W, Lee AL, Lam CLK, Danaei G, et al
    Benefits and Risks Associated With Statin Therapy for Primary Prevention in Old and Very Old Adults : Real-World Evidence From a Target Trial Emulation Study.
    Ann Intern Med. 2024 May 28. doi: 10.7326/M24-0004.
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  46. ALBERTS MJ
    In mild ischemic stroke or high-risk TIA, DAPT started
    Ann Intern Med. 2024 May 7. doi: 10.7326/J24-0029.
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  47. LI XRC
    Web Exclusive. Annals Graphic Medicine - Life After a Stroke.
    Ann Intern Med. 2024;177:eG230020.
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  48. DUNN A
    In older patients with AF and frailty, switching from VKA to NOAC therapy increased a composite of major or CRNM bleeding at 12 mo.
    Ann Intern Med. 2024;177:JC57.
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    April 2024
  49. DRAKE T, Landsteiner A, Langsetmo L, MacDonald R, et al
    Newer Pharmacologic Treatments in Adults With Type 2 Diabetes: A Systematic Review and Network Meta-analysis for the American College of Physicians.
    Ann Intern Med. 2024 Apr 19. doi: 10.7326/M23-1490.
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  50. QASEEM A, Obley AJ, Shamliyan T, Hicks LA, et al
    Newer Pharmacologic Treatments in Adults With Type 2 Diabetes: A Clinical Guideline From the American College of Physicians.
    Ann Intern Med. 2024 Apr 19. doi: 10.7326/M23-2788.
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  51. AJZENBERG H, Binhashr MAN, Hewitt MK, Unger M, et al
    Critical Care: What You May Have Missed in 2023.
    Ann Intern Med. 2024 Apr 16. doi: 10.7326/M24-0565.
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    March 2024
  52. SHADRIN IY, Newby LK
    In subclinical AF, apixaban reduced stroke or systemic embolism but increased major bleeding vs. aspirin at 3.5 y.
    Ann Intern Med. 2024;177:JC26.
    >> Share

    February 2024
  53. KANJEE Z, Dearborn-Tomazos JL, Kumar S, Reynolds EE, et al
    How Would You Prevent Subsequent Strokes in This Patient? Grand Rounds Discussion From Beth Israel Deaconess Medical Center.
    Ann Intern Med. 2024 Feb 13. doi: 10.7326/M23-3136.
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    January 2024
  54. FU EL, Carrero JJ, Sang Y, Evans M, et al
    Association of Low Glomerular Filtration Rate With Adverse Outcomes at Older Age in a Large Population With Routinely Measured Cystatin C.
    Ann Intern Med. 2024 Jan 30. doi: 10.7326/M23-1138.
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  55. HILL MD
    After EVT for ischemic stroke, intensive vs. conventional BP management reduced functional independence at 3 mo.
    Ann Intern Med. 2024 Jan 2. doi: 10.7326/J23-0106.
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    December 2023
  56. SUD M, Sivaswamy A, Austin PC, Anderson TJ, et al
    Development and Validation of the CANHEART Population-Based Laboratory Prediction Models for Atherosclerotic Cardiovascular Disease.
    Ann Intern Med. 2023 Dec 12. doi: 10.7326/M23-1345.
    >> Share

  57. AGARWAL R, Tu W, Farjat AE, Farag YMK, et al
    Impact of Finerenone-Induced Albuminuria Reduction on Chronic Kidney Disease Outcomes in Type 2 Diabetes : A Mediation Analysis.
    Ann Intern Med. 2023 Dec 5. doi: 10.7326/M23-1023.
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  58. WEITZ HH, Merli GJ, Benesch C
    Annals Consult Guys - Surgery After Thromboembolic Stroke.
    Ann Intern Med. 2023;176:eW220025.
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    November 2023
  59. TANG M, Nakamoto CH, Stern AD, Zubizarreta JR, et al
    Effects of Remote Patient Monitoring Use on Care Outcomes Among Medicare Patients With Hypertension : An Observational Study.
    Ann Intern Med. 2023 Nov 7. doi: 10.7326/M23-1182.
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  60. CRUZ-FLORES S
    In healthy older adults, low-dose aspirin did not differ from placebo for ischemic stroke but increased intracranial bleeding.
    Ann Intern Med. 2023 Nov 7. doi: 10.7326/J23-0092.
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  61. TANNU M, Newby LK
    In CAD, P2Y12 inhibitor vs. aspirin monotherapy reduces a composite CV outcome without increasing major bleeding.
    Ann Intern Med. 2023;176:JC123.
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    October 2023
  62. EASTIN C
    In minor, nondisabling, acute ischemic stroke, DAPT was noninferior to IV alteplase for excellent functional outcome at 90 d.
    Ann Intern Med. 2023 Oct 3. doi: 10.7326/J23-0072.
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  63. ALBERTS MJ
    In ischemic stroke without large or medium vessel occlusion, tirofiban increased likelihood of an excellent outcome.
    Ann Intern Med. 2023 Oct 3. doi: 10.7326/J23-0074.
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    September 2023
  64. RIETZ H, Pennlert J, Nordstrom P, Brunstrom M, et al
    Blood Pressure Level in Late Adolescence and Risk for Cardiovascular Events : A Cohort Study.
    Ann Intern Med. 2023 Sep 26. doi: 10.7326/M23-0112.
    >> Share

  65. KIM DH, Lee SB, Park CM, Levin R, et al
    Comparative Safety Analysis of Oral Antipsychotics for In-Hospital Adverse Clinical Events in Older Adults After Major Surgery : A Nationwide Cohort Study.
    Ann Intern Med. 2023 Sep 5. doi: 10.7326/M22-3021.
    >> Share

  66. BANNOW BTS
    In adults with cancer and VTE, DOACs were noninferior to LMWH for recurrent, nonfatal VTE at 6 mo.
    Ann Intern Med. 2023;176:JC104.
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    August 2023
  67. CARLIN S, Douketis J
    In AF, the effects of DOACs vs. warfarin on death and stroke/systemic embolism vary by baseline CrCl level.
    Ann Intern Med. 2023 Aug 1. doi: 10.7326/J23-0054.
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  68. BAHREINI M, Lang E
    In ischemic stroke, EVT improved 90-d function more than usual care across admission SBP levels.
    Ann Intern Med. 2023 Aug 1. doi: 10.7326/J23-0055.
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  69. KIRSCHNER JM, Hunter BR
    SAEM issued 4 strong recommendations (high-certainty evidence) for determining cause of acute vestibular syndrome in the ED.
    Ann Intern Med. 2023;176:JC86.
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    July 2023
  70. MCCORMICK N, Yokose C, Wei J, Lu N, et al
    Comparative Effectiveness of Sodium-Glucose Cotransporter-2 Inhibitors for Recurrent Gout Flares and Gout-Primary Emergency Department Visits and Hospitalizations : A General Population Cohort Study.
    Ann Intern Med. 2023 Jul 25. doi: 10.7326/M23-0724.
    >> Share

  71. ESKIN B
    In ischemic stroke, adding EVT to usual care at 6 to 24 h improved functional status at 90 d.
    Ann Intern Med. 2023 Jul 4. doi: 10.7326/J23-0050.
    >> Share

  72. AL-KHATIB SM
    Atrial Fibrillation.
    Ann Intern Med. 2023;176:ITC97-ITC112.
    >> Share

    June 2023
  73. FERGUSON E, Lang E
    In large acute ischemic stroke, adding endovascular thrombectomy to medical therapy improved function at 90 d.
    Ann Intern Med. 2023 Jun 6. doi: 10.7326/J23-0033.
    >> Share

  74. ALBERTS MJ
    After ICH, starting long-term therapeutic oral anticoagulation in patients with AF reduces MACE at 1 to 3 y.
    Ann Intern Med. 2023;176:JC71.
    >> Share

    May 2023
  75. RAY WA, Chung CP, Stein CM, Smalley W, et al
    Risk for Bleeding-Related Hospitalizations During Use of Amiodarone With Apixaban or Rivaroxaban in Patients With Atrial Fibrillation : A Retrospective Cohort Study.
    Ann Intern Med. 2023 May 23. doi: 10.7326/M22-3238.
    >> Share

  76. RICHARDSON TL JR, Halvorson AE, Hackstadt AJ, Hung AM, et al
    Primary Occurrence of Cardiovascular Events After Adding Sodium-Glucose Cotransporter-2 Inhibitors or Glucagon-like Peptide-1 Receptor Agonists Compared With Dipeptidyl Peptidase-4 Inhibitors: A Cohort Study in Veterans With Diabetes.
    Ann Intern Med. 2023 May 9. doi: 10.7326/M22-2751.
    >> Share

  77. ZHU J, Kamel H, Gupta A, Mushlin AI, et al
    Prioritizing Quality Measures in Acute Stroke Care : A Cost-Effectiveness Analysis.
    Ann Intern Med. 2023 May 2. doi: 10.7326/M22-3186.
    >> Share

  78. GRIFFIN M, Lip GYH
    In limb or pelvic fracture, aspirin was noninferior to enoxaparin for reducing all-cause death.
    Ann Intern Med. 2023;176:JC56.
    >> Share

    April 2023
  79. MARCUCCI M, Painter TW, Conen D, Lomivorotov V, et al
    Hypotension-Avoidance Versus Hypertension-Avoidance Strategies in Noncardiac Surgery : An International Randomized Controlled Trial.
    Ann Intern Med. 2023 Apr 25. doi: 10.7326/M22-3157.
    >> Share

  80. ADIE SK, Konerman MC
    Annals for Hospitalists Inpatient Notes - Sodium-Glucose Cotransporter-2 Inhibitors for Heart Failure With Preserved Ejection Fraction-What Hospitalists Need to Know.
    Ann Intern Med. 2023;176:eM230588.
    >> Share

  81. LADER EW
    After PCI and 6 to 18 mo of DAPT, clopidogrel reduced a composite of clinical events vs. aspirin at 6 y.
    Ann Intern Med. 2023;176:JC38.
    >> Share

  82. PERISETTI A, Sharma P
    In older patients receiving aspirin, H pylori eradication reduced hospitalization or death due to peptic ulcer bleeding at 2.5 y.
    Ann Intern Med. 2023;176:JC45.
    >> Share

    March 2023
  83. FORD ND, DeSisto CL, Galang RR, Kuklina EV, et al
    Cardiac Arrest During Delivery Hospitalization : A Cohort Study.
    Ann Intern Med. 2023 Mar 14. doi: 10.7326/M22-2750.
    >> Share

  84. CHEW DS, Piccini JP
    Left Atrial Appendage Occlusion Versus Oral Anticoagulation in Atrial Fibrillation.
    Ann Intern Med. 2023;176:eL220517.
    >> Share

  85. ANDERSON CE, Lieberman RA, Olshansky B
    Left Atrial Appendage Occlusion Versus Oral Anticoagulation in Atrial Fibrillation.
    Ann Intern Med. 2023;176:eL220516.
    >> Share

  86. DUNN A
    In AF, underdosing of DOACs was not linked to reduced bleeding.
    Ann Intern Med. 2023;176:JC32.
    >> Share


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