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Parkinson's Disease
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Articles published in
Brain Res
    September 2025
  1. KENTROS M, Follett J, Subrahmanian N, Chairmandurai A, et al
    Regulation of LRRK2 activity by metabolic stress and heavy metal exposure.
    Brain Res. 2025;1863:149785.
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  2. YANG B, Jiang T, Li Y, Liu Y, et al
    Changes in gut microbiota and plasma metabolites in Parkinson's disease patients with pain as analyzed by 16S rDNA sequencing and LC-MS.
    Brain Res. 2025 Sep 12:149948. doi: 10.1016/j.brainres.2025.149948.
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  3. ZHUANG Z, Zhang L, Wang Y
    USP2 alleviates MPP(+)-induced neuronal injury by stabilizing FOXC1 in SK-N-SH cells.
    Brain Res. 2025;1862:149689.
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  4. CAI L, Ding Y, Tekreeti AA, Li F, et al
    Remote ischemic conditioning as a potential therapy for Parkinson's Disease: Inhibiting TLR4-Driven neuroinflammation and oxidative damage.
    Brain Res. 2025 Sep 1:149920. doi: 10.1016/j.brainres.2025.149920.
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    August 2025
  5. XU L, Deng J, Xiong W, Li L, et al
    Macrophages in the dCLN are required for alpha-synuclein proteostasis in A53T PD model mice.
    Brain Res. 2025;1860:149692.
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    July 2025
  6. CHEN H, Ding H, Huang D, Wu S, et al
    GBE1 alleviates MPTP-induced PD symptoms in mice by enhancing glycolysis and oxidative phosphorylation.
    Brain Res. 2025;1859:149663.
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  7. AUNG TL, Kan Y, Aung YW, Shi X, et al
    Meta-analysis of long non-coding RNA expression profile in Parkinson's disease.
    Brain Res. 2025 Jul 14:149838. doi: 10.1016/j.brainres.2025.149838.
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  8. AQUINO YC, Pedrao LF, Moreira TS, Falquetto B, et al
    Testosterone modulates respiratory control but does not exert neuroprotective effects in a Parkinson's disease model.
    Brain Res. 2025;1864:149829.
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  9. SI Y, Yan S, Li X, Ding W, et al
    P2X7R activation promotes ferroptosis in dopaminergic neurons via NF-kappaB signaling pathway in vitro and in vivo models of MPP(+)/MPTP-induced Parkinson's disease.
    Brain Res. 2025 Jul 8:149824. doi: 10.1016/j.brainres.2025.149824.
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    June 2025
  10. XIE G, Yang Y, Zhang X, Chen Y, et al
    Tris (1,3-dichloro-2-propyl) phosphate (TDCPP) aggravates Parkinson's disease neurotoxicity through ferroptosis-related oxidative stress and neuroinflammation.
    Brain Res. 2025 Jun 25:149805. doi: 10.1016/j.brainres.2025.149805.
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    May 2025
  11. FOROOZANMEHR B, Hemmati MA, Yaribeygi H, Karav S, et al
    Parkinson's disease and brain insulin signaling: Mechanisms and potential role of GLP-1 mimetics.
    Brain Res. 2025;1862:149738.
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  12. KATRIB C, Naidji C, Devos D, Timmerman K, et al
    Texture features of T2w magnetic resonance imaging mirror tissue changes in Parkinson's disease models.
    Brain Res. 2025 May 19:149717. doi: 10.1016/j.brainres.2025.149717.
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  13. KAUR J, Sharma V, Khan H, Singh S, et al
    Intersecting molecular pathways in Synucleinopathies and Amyloidogenesis: Exploring shared mechanisms and therapeutic potential.
    Brain Res. 2025;1855:149568.
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  14. HYDERI Z, Farhana M S, Singh TP, Ravi AV, et al
    Therapeutic Targeting of Autosomal Parkinson's Disease by Modulation of Leucine-Rich Repeat Kinase 2 (LRRK2) Protein.
    Brain Res. 2025;1860:149674.
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  15. WANG HY, Liang Z, Yan Z, Liu Y, et al
    Neural mechanisms linking sleep disturbances to motor and cognitive impairments in Parkinson's disease: Evidence from resting-state and task-based fNIRS.
    Brain Res. 2025;1860:149681.
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    April 2025
  16. USMAN S, Mondal AC
    Menopause triggers microglia-associated neuroinflammation in Parkinson's disease.
    Brain Res. 2025 Apr 16:149649. doi: 10.1016/j.brainres.2025.149649.
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  17. COTRIN JC, Dos Santos Junior GC, Cadaxo AS, Pereira JS, et al
    Plasma and urinary metabolomic signatures differentiate genetic and idiopathic Parkinson's disease.
    Brain Res. 2025 Apr 7:149625. doi: 10.1016/j.brainres.2025.149625.
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    March 2025
  18. LIU Y, Cheng Y, Chen T, Wang J, et al
    Basal ganglia connectivity and network asymmetry in Parkinson's disease: A resting-state fMRI study.
    Brain Res. 2025 Mar 18:149576. doi: 10.1016/j.brainres.2025.149576.
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  19. MANGANOTTI P, Liccari M, Maria Isabella Lombardo T, Della Toffola J, et al
    Effect of a single session of transcranial pulse stimulation (TPS) on resting tremor in patients with Parkinson's disease.
    Brain Res. 2025;1850:149405.
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    February 2025
  20. KUMAR D, Kumar R, Janrao S, Sharma V, et al
    Treadmill exercise mitigates rotenone-induced neuroinflammation and alpha-synuclein level in a mouse model of Parkinson's disease.
    Brain Res. 2025;1854:149540.
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  21. SAMSON JS, Rajagopal K, Parvathi VD
    Outlook of SNCA (alpha-synuclein) transgenic fly models in delineating the sequel of mitochondrial dysfunction in Parkinson's disease.
    Brain Res. 2025;1852:149505.
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  22. KOOB AO, Shaked GM, Bender A, Bisquertt A, et al
    Corrigendum to "Neurogranin binds alpha-synuclein in the human superior temporal cortex and interaction is decreased in Parkinson's disease" [Brain Res. 1591 (2014) 102-110].
    Brain Res. 2025 Feb 12:149504. doi: 10.1016/j.brainres.2025.149504.
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  23. DUTTA A, Roy R, Pandey M, Chhetry S, et al
    Arsenic-induced mice model of Parkinson's disease: Revealing the neurotoxicity of arsenic through mitochondrial complexes inhibition and dopaminergic neurodegeneration in the substantia nigra region of brain.
    Brain Res. 2025;1851:149493.
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    January 2025
  24. USMAN JS, Wong TW, Ng SSM
    Effects of transcranial direct current stimulation combined with concurrent dual-task walking on mobility, gait, and cognitive outcomes: A systematic review.
    Brain Res. 2025;1846:149255.
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    December 2024
  25. SHARMA R, Thirugnanasambandam N
    Theta-Gamma Decoupling - A neurophysiological marker of impaired reward processing in Parkinson's disease.
    Brain Res. 2024 Dec 19:149406. doi: 10.1016/j.brainres.2024.149406.
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  26. WEN B, Li X, Xu J, He Y, et al
    The mechanism of SiJunZi decoction in the treatment of Parkinson's disease.
    Brain Res. 2024;1850:149397.
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    August 2024
  27. BHARDWAJ K, Jha A, Roy A, Kumar H, et al
    The crucial role of VPS35 and SHH in Parkinson's disease: Understanding the mechanisms behind the neurodegenerative disorder.
    Brain Res. 2024;1845:149204.
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  28. LI Y, Wang Q, Zhang X, Zheng R, et al
    Characterization of D1R and D2R neuronal subpopulations in the globus pallidus interna: Implications for Parkinson's disease pathogenesis.
    Brain Res. 2024 Aug 19:149174. doi: 10.1016/j.brainres.2024.149174.
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  29. LI J, Xu Y, Liu X, Yang F, et al
    Cortical morphological alterations in cognitively normal Parkinson's disease with severe hyposmia.
    Brain Res. 2024;1844:149150.
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  30. SHAH S, Pushpa Tryphena K, Singh G, Kulkarni A, et al
    Neuroprotective role of Carvacrol via Nrf2/HO-1/NLRP3 axis in Rotenone-induced PD mice model.
    Brain Res. 2024;1836:148954.
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    July 2024
  31. CHATTERJEE A, Mohapatra J, Sharma M, Jha A, et al
    A novel selective NLRP3 inhibitor shows disease-modifying potential in animal models of Parkinson's disease.
    Brain Res. 2024 Jul 27:149129. doi: 10.1016/j.brainres.2024.149129.
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  32. STATZ M, Weber H, Schleuter F, Kober M, et al
    Subthalamic nucleus deep brain stimulation induces functional deficits in norepinephrinergic neurotransmission in a Parkinson's disease model.
    Brain Res. 2024 Jul 23:149128. doi: 10.1016/j.brainres.2024.149128.
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    June 2024
  33. JIN M, Ye K, Hu D, Chen J, et al
    Identification of diagnose related therapeutic targets of Danggui buxue decoction in Parkinson's disease.
    Brain Res. 2024 Jun 29:149097. doi: 10.1016/j.brainres.2024.149097.
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  34. MA LY, Jia B, Geng H, Liang J, et al
    Poly(rC)-binding protein 1 alleviates neurotoxicity in 6-OHDA-induced SH-SY5Y cells and modulates glial cells in neuroinflammation.
    Brain Res. 2024;1832:148863.
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    May 2024
  35. LI L, Chen Z, Hao C
    Neuroprotective effects of polyphyllin VI against rotenone-induced toxicity in SH-SY5Y cells.
    Brain Res. 2024;1830:148824.
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    April 2024
  36. HOFFMEISTER JD, Broadfoot CK, Schaen-Heacock NE, Lechner SA, et al
    Vocal and tongue exercise in early to mid-stage Parkinson disease using the Pink1-/- rat.
    Brain Res. 2024 Apr 27:148958. doi: 10.1016/j.brainres.2024.148958.
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  37. CANSIZ D, Unal I, Gani Surmen M, Surmen S, et al
    Gentisic acid exerts neuroprotective effects in neurotoxin-induced Parkinson's disease model in zebrafish: Cross-talk between pathways related with neurodegeneration in the gut-brain axis.
    Brain Res. 2024 Apr 19:148952. doi: 10.1016/j.brainres.2024.148952.
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    March 2024
  38. ROSTAMI Z, Salari M, Mahdavi S, Etemadifar M, et al
    Abnormal multisensory temporal discrimination in Parkinson's disease.
    Brain Res. 2024 Mar 30:148901. doi: 10.1016/j.brainres.2024.148901.
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  39. MANSOUR HM, Mohamed AF, Khattab MM, El-Khatib AS, et al
    Unveiling the therapeutic prospects of EGFR inhibition in rotenone-mediated parkinsonism in rats: Modulation of dopamine D3 receptor.
    Brain Res. 2024;1834:148893.
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  40. GENG C, Tan L, Chenchen
    Neuropsychiatric symptoms profile and markers of Alzheimer disease-type pathology in patients with Lewy body dementias.
    Brain Res. 2024 Mar 20:148881. doi: 10.1016/j.brainres.2024.148881.
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    December 2023
  41. FLORES AJ, Bartlett MJ, Seaton BT, Samtani G, et al
    Antagonism of kappa opioid receptors accelerates the development of L-DOPA-induced dyskinesia in a preclinical model of moderate dopamine depletion.
    Brain Res. 2023;1821:148613.
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    November 2023
  42. SMIT RD, Ghosh B, Campion TJ 3rd, Stingel R, et al
    STAT3 protects dopaminergic neurons against degeneration in animal model of Parkinson's disease.
    Brain Res. 2023;1824:148691.
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  43. LIU X, Liu X, Liu Y, Yang B, et al
    Utility of serum neurofilament light chain and glial fibrillary acidic protein as diagnostic biomarkers of freezing of gait in Parkinson's disease.
    Brain Res. 2023;1822:148660.
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  44. ZHANG L, Guo Y, Liu J, Li L, et al
    Transcranial direct current stimulation of the prefrontal cortex improves depression-like behaviors in rats with Parkinson's disease.
    Brain Res. 2023 Nov 1:148649. doi: 10.1016/j.brainres.2023.148649.
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    October 2023
  45. ISMAEL S, Colvin RA, Lee D
    Activation of cyclic AMP signaling pathway in dopaminergic neurons rescues locomotion defects in a Drosophila larval model of Parkinson's disease.
    Brain Res. 2023 Oct 20:148641. doi: 10.1016/j.brainres.2023.148641.
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    September 2023
  46. YIN N, Wang H, Wang Z, Feng K, et al
    A study of brain networks associated with Freezing of gait in Parkinson's disease using transfer entropy analysis.
    Brain Res. 2023 Sep 30:148610. doi: 10.1016/j.brainres.2023.148610.
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  47. CABRAL LM, Oliveira LM, Miranda NC, Kawamoto EM, et al
    TNFR1-mediated neuroinflammation is necessary for respiratory deficits observed in 6-hydroxydopamine mouse model of Parkinsons Disease.
    Brain Res. 2023 Sep 25:148586. doi: 10.1016/j.brainres.2023.148586.
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  48. SONG J, Zhao Y, Shan X, Luo Y, et al
    Active ingredients of Chinese medicine with immunomodulatory properties: NF-kappaB pathway and Parkinson's disease.
    Brain Res. 2023 Sep 23:148603. doi: 10.1016/j.brainres.2023.148603.
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    August 2023
  49. UNAL I, Cansiz D, Beler M, Sezer Z, et al
    Sodium-dependent Glucose Co-Transporter-2 Inhibitor Empagliflozin Exerts Neuroprotective Effects in Rotenone-Induced Parkinson's Disease Model in Zebrafish; Mechanism Involving Ketogenesis and Autophagy.
    Brain Res. 2023 Aug 15:148536. doi: 10.1016/j.brainres.2023.148536.
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    June 2023
  50. KHOT M, Sood A, Pushpa Tryphena K, Pinjala P, et al
    Dimethyl fumarate ameliorates Parkinsonian pathology by modulating autophagy and apoptosis via Nrf2-TIGAR-LAMP2/Cathepsin D axis.
    Brain Res. 2023 Jun 12:148462. doi: 10.1016/j.brainres.2023.148462.
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  51. RAI P, Ratnaparkhi A, Kumar Roy J
    Rab11 rescues muscle degeneration and synaptic morphology in the park(13/+) Parkinson model of Drosophila melanogaster.
    Brain Res. 2023 Jun 9:148442. doi: 10.1016/j.brainres.2023.148442.
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  52. OLIVEIRA LM, Severs L, Moreira TS, Ramirez JM, et al
    Ampakine CX614 increases respiratory rate in a mouse model of Parkinson's disease.
    Brain Res. 2023;1815:148448.
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  53. ZHOU W, He J, Zhang C, Pan Y, et al
    Fiber-specific white matter alterations in Parkinson's disease patients with freezing of gait.
    Brain Res. 2023 Jun 2:148440. doi: 10.1016/j.brainres.2023.148440.
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    May 2023
  54. HENRIQUE BINDA K, Landau AM, Chacur M, Brooks DJ, et al
    Treadmill exercise modulates nigral and hippocampal cannabinoid receptor type 1 in the 6-OHDA model of Parkinson's disease.
    Brain Res. 2023 May 31:148436. doi: 10.1016/j.brainres.2023.148436.
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  55. ROUZITALAB A, Boulay CB, Sachs AJ
    Volitional Control of Beta Activities in Parkinson's Disease Patients.
    Brain Res. 2023 May 6:148394. doi: 10.1016/j.brainres.2023.148394.
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    April 2023
  56. CONTI MAZZA MM, Centner A, Werner DF, Bishop C, et al
    Striatal serotonin transporter gain-of-function in L-DOPA-treated, hemi-parkinsonian rats.
    Brain Res. 2023 Apr 29:148381. doi: 10.1016/j.brainres.2023.148381.
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    March 2023
  57. BOSCH TJ, Espinoza AI, Singh A
    Cerebellar oscillatory dysfunction during lower-limb movement in Parkinson's disease with freezing of gait.
    Brain Res. 2023;1808:148334.
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  58. NING B, Wang Z, Wu Q, Deng Q, et al
    Acupuncture inhibits autophagy and repairs synapses by activating the mTOR pathway in Parkinson's disease depression model rats.
    Brain Res. 2023 Mar 11:148320. doi: 10.1016/j.brainres.2023.148320.
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