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Articles published in
Proc Natl Acad Sci U S A
    November 2025
  1. LI YR, Shen X, Zhu E, Li Z, et al
    Targeting orthotopic and metastatic pancreatic cancer with allogeneic stem cell-engineered mesothelin-redirected CAR-NKT cells.
    Proc Natl Acad Sci U S A. 2025;122:e2517786122.
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  2. YANG X, Wang Y, Zhou J, Li S, et al
    Engineering a spatiotemporal macrophage circuit via STING phase separation to override immune suppression in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2025;122:e2504718122.
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    September 2025
  3. CHUANG PK, Chung C, Liao KS, Wong CH, et al
    Improving the efficacy of anti-SSEA4 antibody in pancreatic cancer immunotherapy with glyco-optimization and immune checkpoint blockade.
    Proc Natl Acad Sci U S A. 2025;122:e2517415122.
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    August 2025
  4. YUAN S, Yang X, Bremmer AM, Wang Y, et al
    Programmable immunoprobiotics orchestrate antitumor immune response with Pin1 inhibition for pancreatic cancer treatment.
    Proc Natl Acad Sci U S A. 2025;122:e2507711122.
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    July 2025
  5. MORESCO P, Kastan JP, Yang JI, Prabakar R, et al
    Signal peptide-independent secretion of keratin-19 by pancreatic cancer cells.
    Proc Natl Acad Sci U S A. 2025;122:e2426218122.
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    April 2025
  6. VINAIXA J, Martinez-Bosch N, Gibert J, Manero-Ruperez N, et al
    Nuclear Galectin-1 promotes KRAS-dependent activation of pancreatic cancer stellate cells.
    Proc Natl Acad Sci U S A. 2025;122:e2424051122.
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    March 2025
  7. ZHU Q, Yu C, Chen Y, Luo W, et al
    Dual mRNA nanoparticles strategy for enhanced pancreatic cancer treatment and beta-elemene combination therapy.
    Proc Natl Acad Sci U S A. 2025;122:e2418306122.
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    October 2024
  8. YANG Y, Wang B, Dong H, Lin H, et al
    The mitochondrial enzyme pyruvate carboxylase restricts pancreatic beta-cell senescence by blocking p53 activation.
    Proc Natl Acad Sci U S A. 2024;121:e2401218121.
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    August 2024
  9. KITAMURA RA, Hummel D, Ustione A, Piston DW, et al
    Dual role of neuroplastin in pancreatic beta cells: Regulating insulin secretion and promoting islet inflammation.
    Proc Natl Acad Sci U S A. 2024;121:e2411234121.
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  10. SU W, Kochen Rossi J, Nuevo-Tapioles C, Chen T, et al
    UPF1 deficiency enhances mitochondrial ROS which promotes an immunosuppressive microenvironment in pancreatic ductal adenocarcinoma.
    Proc Natl Acad Sci U S A. 2024;121:e2401996121.
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    July 2024
  11. AMIT U, Uslu U, Verginadis II, Kim MM, et al
    Proton radiation boosts the efficacy of mesothelin-targeting chimeric antigen receptor T cell therapy in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2024;121:e2403002121.
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  12. LI J, Moresco P, Fearon DT
    Intratumoral NKT cell accumulation promotes antitumor immunity in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2024;121:e2403917121.
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    April 2024
  13. HIYOSHI H, Sakuma K, Asano S, Napier SC, et al
    Identification and removal of unexpected proliferative off-target cells emerging after iPSC-derived pancreatic islet cell implantation.
    Proc Natl Acad Sci U S A. 2024;121:e2320883121.
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  14. MURTHY D, Attri KS, Suresh V, Rajacharya GH, et al
    The MUC1-HIF-1alpha signaling axis regulates pancreatic cancer pathogenesis through polyamine metabolism remodeling.
    Proc Natl Acad Sci U S A. 2024;121:e2315509121.
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    August 2023
  15. DASGUPTA A, Gibbard DF, Schmitt RE, Arneson-Wissink PC, et al
    A TGF-beta/KLF10 signaling axis regulates atrophy-associated genes to induce muscle wasting in pancreatic cancer.
    Proc Natl Acad Sci U S A. 2023;120:e2215095120.
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    May 2023
  16. CHANDA D, Thoudam T, Sinam IS, Lim CW, et al
    Upregulation of the ERRgamma-VDAC1 axis underlies the molecular pathogenesis of pancreatitis.
    Proc Natl Acad Sci U S A. 2023;120:e2219644120.
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    March 2023

  17. Correction for Taylor et al., Human pancreatic islet microRNAs implicated in diabetes and related traits by large-scale genetic analysis.
    Proc Natl Acad Sci U S A. 2023;120:e2302726120.
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  18. MELLO SS, Flowers BM, Mazur PK, Lee JJ, et al
    Multifaceted role for p53 in pancreatic cancer suppression.
    Proc Natl Acad Sci U S A. 2023;120:e2211937120.
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