September 2025
1. CHOWDHURY SR, Parikh CN, Kaur AN, DeMarco KD, et al
   PPT1 is a negative regulator of STING signaling in cancer cells and its inhibition reactivates immune surveillance in cold tumors.
   Proc Natl Acad Sci U S A. 2025;122:e2514948122.
   

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2. ALENCAR GF, Mohamed AO, Burnett MG, Jean SS, et al
   Triple checkpoint blockade of PD-1, Tim-3, and Lag-3 enhances adoptive T cell immunotherapy in a mouse model of ovarian cancer.
   Proc Natl Acad Sci U S A. 2025;122:e2419888122.
   

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   July 2025
3. FREDERICK J, Virk RKA, Ye IC, Almassalha LM, et al
   Leveraging chromatin packing domains to target chemoevasion in vivo.
   Proc Natl Acad Sci U S A. 2025;122:e2425319122.
   

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4. SUN R, Jiang P, Wang Z, Yan B, et al
   DNA2 protein destruction dictates DNA hyperexcision, cGAS-STING activation, and innate immune response in CDK12-deregulated cancers.
   Proc Natl Acad Sci U S A. 2025;122:e2413732122.
   

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   June 2025
5. TIEN JC, Zhai Y, Wu R, Zhang Y, et al
   Defining CDK12 as a tumor suppressor and therapeutic target in mouse models of tubo-ovarian high-grade serous carcinoma.
   Proc Natl Acad Sci U S A. 2025;122:e2426909122.
   

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6. LAMPERIS SM, McMahon KM, Calvert AE, Rink JS, et al
   CRISPR screen reveals a simultaneous targeted mechanism to reduce cancer cell selenium and increase lipid oxidation to induce ferroptosis.
   Proc Natl Acad Sci U S A. 2025;122:e2502876122.
   

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   November 2024
7. RAVINDRANATHAN R, Somuncu O, da Costa AABA, Mukkavalli S, et al
   PARG inhibitor sensitivity correlates with accumulation of single-stranded DNA gaps in preclinical models of ovarian cancer.
   Proc Natl Acad Sci U S A. 2024;121:e2413954121.
   

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8. NACIRI I, Liang M, Yang Y, Karner H, et al
   Loss of XIST lncRNA unlocks stemness and cellular plasticity in ovarian cancer.
   Proc Natl Acad Sci U S A. 2024;121:e2418096121.
   

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   May 2024
9. NAN Y, Wu X, Luo Q, Chang W, et al
   OTUB2 silencing promotes ovarian cancer via mitochondrial metabolic reprogramming and can be synthetically targeted by CA9 inhibition.
   Proc Natl Acad Sci U S A. 2024;121:e2315348121.
   

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   March 2024
10. HAO L, Boehnke N, Elledge SK, Harzallah NS, et al
    Targeting and monitoring ovarian cancer invasion with an RNAi and peptide delivery system.
    Proc Natl Acad Sci U S A. 2024;121:e2307802121.
    

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