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Articles published in
Proc Natl Acad Sci U S A
    September 2025
  1. WESTERMANN FG, Oken AC, Granith PKE, Marimuthu P, et al
    Subtype-specific structural features of the hearing loss-associated human P2X2 receptor.
    Proc Natl Acad Sci U S A. 2025;122:e2417753122.
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  2. LI XJ, Morgan C, Duy PQ, Evsen L, et al
    The RNA-binding protein TRIM71 is essential for hearing in humans and mice and times auditory sensory organ development.
    Proc Natl Acad Sci U S A. 2025;122:e2505811122.
    >> Share

    August 2025
  3. ZHAO Z, Li A, Zhu Y, Cen S, et al
    Blood-labyrinth barrier damage mediated by granzymes from cytotoxic lymphocytes results in hearing loss in systemic lupus erythematosus.
    Proc Natl Acad Sci U S A. 2025;122:e2423240122.
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    June 2025
  4. LIANG C, Zhai TY, Chen J, Fang S, et al
    ATP-gated P2x7 receptors express at type II auditory nerves and required for efferent hearing control and noise protection.
    Proc Natl Acad Sci U S A. 2025;122:e2421995122.
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    May 2025
  5. MARTIN M, Bolognesi B
    Massive mutagenesis reveals an incomplete amyloid motif in Bri2 that turns amyloidogenic upon C-terminal extension.
    Proc Natl Acad Sci U S A. 2025;122:e2415521122.
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  6. HENNIG M, Bhattacharjee RB, Agarwal I, Alfaifi A, et al
    Inhaled DNAI1 mRNA therapy for treatment of primary ciliary dyskinesia.
    Proc Natl Acad Sci U S A. 2025;122:e2421915122.
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    April 2025
  7. SCHNUPP JWH, Buchholz S, Buck AN, Budig H, et al
    Pulse timing dominates binaural hearing with cochlear implants.
    Proc Natl Acad Sci U S A. 2025;122:e2416697122.
    >> Share

    March 2025
  8. BEURG M, Konrad DE, Fettiplace R
    Hair cell apoptosis and deafness in Tmc1 mutations.
    Proc Natl Acad Sci U S A. 2025;122:e2425215122.
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  9. XIAO Y, Zhang X, Guo S, Liu Z, et al
    GSDMD-mediated mitochondrial dysfunction in marginal cells: A potential driver of inflammation and stria vascularis damage in CIHL.
    Proc Natl Acad Sci U S A. 2025;122:e2415805122.
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    February 2025
  10. LI J, Oh SI, Liu C, Zhao B, et al
    Inhibition of GABARAP or GABARAPL1 prevents aminoglycoside- induced hearing loss.
    Proc Natl Acad Sci U S A. 2025;122:e2416453122.
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    December 2024
  11. PATEL A, Pauzuolyte V, Ingham NJ, Leong YC, et al
    Rescue of cochlear vascular pathology prevents sensory hair cell loss in Norrie disease.
    Proc Natl Acad Sci U S A. 2024;121:e2322124121.
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    November 2024
  12. WANG Y, Thakur D, Duge E, Murphy C, et al
    Deafness due to loss of a TRPV channel eliminates mating behavior in Aedes aegypti males.
    Proc Natl Acad Sci U S A. 2024;121:e2404324121.
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    June 2024
  13. MASRI S, Mowery TM, Fair R, Sanes DH, et al
    Developmental hearing loss-induced perceptual deficits are rescued by genetic restoration of cortical inhibition.
    Proc Natl Acad Sci U S A. 2024;121:e2311570121.
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    May 2024
  14. GOTO S, Tsutsumi A, Lee Y, Hosojima M, et al
    Cryo-EM structures elucidate the multiligand receptor nature of megalin.
    Proc Natl Acad Sci U S A. 2024;121:e2318859121.
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    April 2024
  15. ROMMELSPACHER H, Bera S, Brommer B, Ward R, et al
    A single dose of AC102 restores hearing in a guinea pig model of noise-induced hearing loss to almost prenoise levels.
    Proc Natl Acad Sci U S A. 2024;121:e2314763121.
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    March 2024
  16. ZHAO W, Zhang K, Dong WY, Tang HD, et al
    A pharynx-to-brain axis controls pharyngeal inflammation-induced anxiety.
    Proc Natl Acad Sci U S A. 2024;121:e2312136121.
    >> Share

  17. LI N, Liu S, Zhao D, Du H, et al
    Disruption of Cdh23 exon 68 splicing leads to progressive hearing loss in mice by affecting tip-link stability.
    Proc Natl Acad Sci U S A. 2024;121:e2309656121.
    >> Share


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