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Articles published in
Diabetes
    May 2024
  1. SHEN KC, Collins KH, Ferey JLA, Fappi A, et al
    Excess Intramyocellular Lipid Does Not Affect Muscle Fiber Biophysical Properties in Mice or People with Metabolically Abnormal Obesity.
    Diabetes. 2024 May 3:db230991. doi: 10.2337/db23-0991.
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  2. GUPTA OT, Gupta RK
    The Expanding Problem of Regional Adiposity: Revisiting a 1985 Diabetes Classic by Ohlson et al.
    Diabetes. 2024;73:649-652.
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  3. LEE SH, Suh JH, Heo MJ, Choi JM, et al
    The Hepatokine Orosomucoid 2 Mediates Beneficial Metabolic Effects of Bile Acids.
    Diabetes. 2024;73:701-712.
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    April 2024
  4. SMEEHUIJZEN L, Gijbels A, Nugteren-Boogaard JP, Vrieling F, et al
    Immunometabolic Signatures of Circulating Monocytes in Humans with Obesity and Insulin Resistance.
    Diabetes. 2024 Apr 24:db230970. doi: 10.2337/db23-0970.
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  5. LIU J, Aylor KW, Liu Z
    Erratum. Liraglutide and Exercise Synergistically Attenuate Vascular Inflammation and Enhance Metabolic Insulin Action in Early Diet-Induced Obesity. Diabetes 2023;72:918-931.
    Diabetes. 2024 Apr 23:db24er07a. doi: 10.2337.
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  6. PURNELL JQ
    Metabolic-Bariatric Surgery for Type 2 Diabetes: Time(ing) for a Change.
    Diabetes. 2024;73:542-544.
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    March 2024
  7. ABRAHAM A, Cule M, Thanaj M, Basty N, et al
    Genetic evidence for distinct biological mechanisms that link adiposity to type 2 diabetes: towards precision medicine.
    Diabetes. 2024 Mar 26:db231005. doi: 10.2337/db23-1005.
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  8. RAMSHANKAR G, Perry RJ
    A New Mitochondrial Uncoupler Improves Metabolic Homeostasis in Mice.
    Diabetes. 2024;73:357-358.
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  9. RIERA CE
    Wiring the Brain for Wellness: Sensory Integration in Feeding and Thermogenesis: A Report on Research Supported by Pathway to Stop Diabetes.
    Diabetes. 2024;73:338-347.
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    February 2024
  10. LI X, Su Y, Xu Y, Hu T, et al
    Adipocyte-specific Hnrnpa1 knockout aggravates obesity-induced metabolic dysfunction via upregulating of CCL2.
    Diabetes. 2024 Feb 6:db230609. doi: 10.2337/db23-0609.
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  11. GILANI A, Stoll L, Homan EA, Lo JC, et al
    Adipose Signals Regulating Distal Organ Health and Disease.
    Diabetes. 2024;73:169-177.
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  12. VALI A, Dalle H, Loubaresse A, Gilleron J, et al
    Adipocyte Glucocorticoid Receptor Activation With High Glucocorticoid Doses Impairs Healthy Adipose Tissue Expansion by Repressing Angiogenesis.
    Diabetes. 2024;73:211-224.
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  13. HUANG J, Zhang Y, Zhou X, Song J, et al
    Foxj3 Regulates Thermogenesis of Brown and Beige Fat Via Induction of PGC-1alpha.
    Diabetes. 2024;73:178-196.
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  14. ZHAO S, Li N, Xiong W, Li G, et al
    Leptin Reduction as a Required Component for Weight Loss.
    Diabetes. 2024;73:197-210.
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  15. FURBER EC, Hyatt K, Collins K, Yu X, et al
    GIPR Agonism Enhances TZD-Induced Insulin Sensitivity in Obese IR Mice.
    Diabetes. 2024;73:292-305.
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    January 2024
  16. BACHA F, El-Ayash H, Mohamad M, Sharma S, et al
    Distinct Amino Acid Profile Characterizes Youth with or at risk for Type 2 Diabetes.
    Diabetes. 2024 Jan 12:db230375. doi: 10.2337/db23-0375.
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  17. PURVIS GSD, Collino M, van Dam AD, Einaudi G, et al
    OxPhos in adipose tissue macrophages regulated by BTK enhances their M2-like phenotype and confers a systemic immunometabolic benefit in obesity.
    Diabetes. 2024 Jan 8:db220275. doi: 10.2337/db22-0275.
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  18. HUANG M, Prasad RB, Coral DE, Hjort L, et al
    Human Genetic Variation at rs10071329 Correlates with Adiposity-related Traits, Modulates PPARGC1B Expression, and Alters Brown Adipocyte Function.
    Diabetes. 2024 Jan 8:db230531. doi: 10.2337/db23-0531.
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  19. WANG D, Jabile MJT, Lu J, Townsend LK, et al
    Fatty Acids Increase GDF15 and Reduce Food Intake Through a GFRAL Signaling Axis.
    Diabetes. 2024;73:51-56.
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    December 2023
  20. LUK CT, Chan CK, Chiu F, Shi SY, et al
    Dual Role of Caspase 8 in Adipocyte Apoptosis and Metabolic Inflammation.
    Diabetes. 2023;72:1751-1765.
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    November 2023
  21. KELLER MP, O'Connor C, Bitzer M, Schueler KL, et al
    Genetic analysis of obesity-induced diabetic nephropathy in BTBR mice.
    Diabetes. 2023 Nov 7:db230444. doi: 10.2337/db23-0444.
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  22. BROTMAN SM, Oravilahti A, Rosen JD, Alvarez M, et al
    Cell-Type Composition Affects Adipose Gene Expression Associations With Cardiometabolic Traits.
    Diabetes. 2023;72:1707-1718.
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  23. HUANG Y, Hertzel AV, Fish SR, Halley CL, et al
    TP53/p53 Facilitates Stress-Induced Exosome and Protein Secretion by Adipocytes.
    Diabetes. 2023;72:1560-1573.
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    October 2023
  24. WRIGHT JJ, Eskaros A, Windon A, Bottino R, et al
    Exocrine pancreas in type 1 and type 2 diabetes: different patterns of fibrosis, metaplasia, angiopathy, and adiposity.
    Diabetes. 2023 Oct 26:db230009. doi: 10.2337/db23-0009.
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  25. MASHAYEKHI M, Nian H, Mayfield D, Devin JK, et al
    Weight Loss-Independent Effect of Liraglutide on Insulin Sensitivity in Individuals with Obesity and Pre-Diabetes.
    Diabetes. 2023 Oct 24:db230356. doi: 10.2337/db23-0356.
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  26. BERETTA M, Dai Y, Olzomer EM, Vancuylenburg CS, et al
    Liver-selective imidazolopyrazine mitochondrial uncoupler SHD865 reverses adiposity and glucose intolerance in mice.
    Diabetes. 2023 Oct 23:db230233. doi: 10.2337/db23-0233.
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  27. TRICO D, Chiriaco M, Nouws J, Vash-Margita A, et al
    Alterations in adipose tissue distribution, cell morphology and function mark primary insulin hypersecretion in youths with obesity.
    Diabetes. 2023 Oct 23:db230450. doi: 10.2337/db23-0450.
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  28. BONET ML, Ribot J, Pico C
    Decoding the Mechanisms Behind Early Weaning-Driven Obesity and the Leucine "Solution".
    Diabetes. 2023;72:1347-1349.
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    September 2023
  29. FELIX JF, Grant SFA
    Keeping It in the Family: Consanguinity Reveals P4HTM as a Novel Syndromic Obesity Gene.
    Diabetes. 2023;72:1184-1186.
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  30. PAN Q, Ai W, Chen Y, Kim DM, et al
    Reciprocal Regulation of Hepatic TGF-beta1 and Foxo1 Controls Gluconeogenesis and Energy Expenditure.
    Diabetes. 2023;72:1193-1206.
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    August 2023
  31. DENG Y, Liu X, Xie M, Zhao R, et al
    Obesity enables NLRP3 activation and induces myocardial fibrosis via hyperacetylation of HADHa.
    Diabetes. 2023 Aug 25:db230264. doi: 10.2337/db23-0264.
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  32. ZHONG Y, Wang Y, Li X, Qin H, et al
    PRMT4 Facilitates White Adipose Tissue Browning and Thermogenesis by Methylating PPARgamma.
    Diabetes. 2023;72:1095-1111.
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    July 2023
  33. CHRISTIANSEN MR, Kilpelainen TO, Mccaffery JM
    Abdominal obesity genetic variants predict waist circumference regain after weight loss.
    Diabetes. 2023 Jul 26:db230131. doi: 10.2337/db23-0131.
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  34. ZARINI S, Zemski Berry KA, Kahn DE, Garfield A, et al
    Deoxysphingolipids: Atypical Skeletal Muscle Lipids Related to Insulin Resistance in Humans That Decrease Insulin Sensitivity In Vitro.
    Diabetes. 2023;72:884-897.
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  35. PETRICK HL, Ogilvie LM, Brunetta HS, Robinson A, et al
    Dietary Nitrate and Corresponding Gut Microbiota Prevent Cardiac Dysfunction in Obese Mice.
    Diabetes. 2023;72:844-856.
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    June 2023
  36. CHEN YC, Taylor AJ, Fulcher JM, Swensen AC, et al
    Deletion of carboxypeptidase E in beta cells disrupts proinsulin processing but does not lead to spontaneous development of diabetes in mice.
    Diabetes. 2023 Jun 26:db220945. doi: 10.2337/db22-0945.
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    May 2023
  37. ZENG L, Herdman DS, Lee SM, Tao A, et al
    Loss of cAMP signaling in CD11c immune cells protects against diet-induced obesity.
    Diabetes. 2023 May 31:db221035. doi: 10.2337/db22-1035.
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  38. HUANG X, Zhao Y, Liu T, Wu D, et al
    beta-cell function and insulin dynamics in obese patients with and without diabetes after sleeve gastrectomy.
    Diabetes. 2023 May 31:db221048. doi: 10.2337/db22-1048.
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  39. XIE R, Yan S, Zhou X, Gao Y, et al
    Activation of METTL3 promotes white adipose tissue beiging and combats obesity.
    Diabetes. 2023 May 24:db220775. doi: 10.2337/db22-0775.
    >> Share

  40. NGUYEN A, Khafagy R, Gao Y, Meerasa A, et al
    Erratum. Association Between Obesity and Chronic Kidney Disease: Multivariable Mendelian Randomization Analysis and Observational Data From a Bariatric Surgery Cohort. Diabetes 2023;72:496-510.
    Diabetes. 2023 May 18:db23er08a. doi: 10.2337.
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  41. SUN Y, Sun B, Han X, Shan A, et al
    Leucine supplementation ameliorates early life "programming" of obesity in rats.
    Diabetes. 2023 May 17:db220862. doi: 10.2337/db22-0862.
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  42. REYNOLDS GP
    Comment on Tabatabaei Dakhili et al. The Antipsychotic Dopamine 2 Receptor Antagonist Diphenylbutylpiperidines Improve Glycemia in Experimental Obesity by Inhibiting Succinyl-CoA:3-Ketoacid CoA Transferase. Diabetes 2023;72:126-134.
    Diabetes. 2023;72:e5.
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    April 2023
  43. SAEED S, Ning L, Badreddine A, Mirza MU, et al
    Biallelic mutations in P4HTM cause syndromic obesity.
    Diabetes. 2023 Apr 21:db221017. doi: 10.2337/db22-1017.
    >> Share

  44. LIU J, Aylor KW, Liu Z
    Liraglutide and Exercise Synergistically Attenuate Vascular Inflammation and Enhance Metabolic Insulin Action in Early Diet-induced Obesity.
    Diabetes. 2023 Apr 19:db220745. doi: 10.2337/db22-0745.
    >> Share

  45. LIU C, Meng M, Xu B, Xu Y, et al
    Fibroblast Growth Factor 6 Promotes Adipocyte Progenitor Cell Proliferation for Adipose Tissue Homeostasis.
    Diabetes. 2023;72:467-482.
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    March 2023
  46. VIDMAR AP, Durazo-Arvizu R, Weigensberg MJ, Alderete TL, et al
    Rapid Decline in Beta-Cell Function and Increasing Adiposity is Associated with Conversion to Type 2 Diabetes in at Risk Latino Youth.
    Diabetes. 2023 Mar 27:db221034. doi: 10.2337/db22-1034.
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  47. LUAN D, Dadpey B, Zaid J, Bridge-Comer PE, et al
    Adipocyte-Secreted IL-6 Sensitizes Macrophages to IL-4 Signaling.
    Diabetes. 2023;72:367-374.
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  48. ANDERSSON DP, Kerr AG, Dahlman I, Ryden M, et al
    Relationship Between a Sedentary Lifestyle and Adipose Insulin Resistance.
    Diabetes. 2023;72:316-325.
    >> Share

    February 2023
  49. DRYGALSKI K, Lecoutre S, Clement K, Dugail I, et al
    Hyaluronan in Adipose Tissue, Metabolic Inflammation, and Diabetes: Innocent Bystander or Guilty Party?
    Diabetes. 2023;72:159-169.
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  50. XU J, Liu Z, Zhang J, Chen S, et al
    N-end Rule-Mediated Proteasomal Degradation of ATGL Promotes Lipid Storage.
    Diabetes. 2023;72:210-222.
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    January 2023
  51. NGUYEN A, Khafagy R, Gao Y, Meerasa A, et al
    Association between obesity and chronic kidney disease: multivariable Mendelian randomization analysis and observational data from a bariatric surgery cohort.
    Diabetes. 2023 Jan 19:db220696. doi: 10.2337/db22-0696.
    >> Share

  52. CHEN ZZ, Gao Y, Keyes MJ, Deng S, et al
    Protein Markers of Diabetes Discovered in an African American Cohort.
    Diabetes. 2023 Jan 11:db220710. doi: 10.2337/db22-0710.
    >> Share

  53. BALAKRISHNAN B, Gupta A, Basri R, Sharma VM, et al
    Endothelial-Specific Expression of CIDEC Improves High-Fat Diet-Induced Vascular and Metabolic Dysfunction.
    Diabetes. 2023;72:19-32.
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  54. REGUE L, Wang W, Ji F, Avruch J, et al
    Human T2D-Associated Gene IMP2/IGF2BP2 Promotes the Commitment of Mesenchymal Stem Cells Into Adipogenic Lineage.
    Diabetes. 2023;72:33-44.
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    December 2022
  55. LV S, Hu T, Zhang R, Zhou Y, et al
    Rhamnose Displays an Anti-obesity Effect through Stimulating Adipose Dopamine Receptors and Thermogenesis.
    Diabetes. 2022 Dec 6:db220552. doi: 10.2337/db22-0552.
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  56. PATRA D, Roy S, Arora L, Kabeer SW, et al
    miR-210-3p promotes obesity-induced adipose tissue inflammation and insulin resistance by targeting SOCS1 mediated NF-kappaB pathway.
    Diabetes. 2022 Dec 5:db220284. doi: 10.2337/db22-0284.
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    November 2022
  57. STRANAHAN AM, Guo DH, Yamamoto M, Hernandez CM, et al
    Sex Differences in Adipose Tissue Distribution Determine Susceptibility to Neuroinflammation in Mice With Dietary Obesity.
    Diabetes. 2022 Nov 11. pii: 147893. doi: 10.2337/db22-0192.
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  58. LUO W, Kim Y, Jensen ME, Herlea-Pana O, et al
    miR-130b/301b Is a Negative Regulator of Beige Adipogenesis and Energy Metabolism In Vitro and In Vivo.
    Diabetes. 2022;71:2360-2371.
    >> Share

  59. WINN NC, Cottam MA, Bhanot M, Caslin HL, et al
    Weight Cycling Impairs Pancreatic Insulin Secretion but Does Not Perturb Whole-Body Insulin Action in Mice With Diet-Induced Obesity.
    Diabetes. 2022;71:2313-2330.
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  60. YAO T, Yan H, Zhu X, Zhang Q, et al
    Obese Skeletal Muscle-Expressed Interferon Regulatory Factor 4 Transcriptionally Regulates Mitochondrial Branched-Chain Aminotransferase Reprogramming Metabolome.
    Diabetes. 2022;71:2256-2271.
    >> Share

  61. NIRAULA A, Fasnacht RD, Ness KM, Frey JM, et al
    Prostaglandin PGE2 Receptor EP4 Regulates Microglial Phagocytosis and Increases Susceptibility to Diet-Induced Obesity.
    Diabetes. 2022 Nov 1. pii: 147843. doi: 10.2337/db21-1072.
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    October 2022
  62. TABATABAEI DAKHILI SA, Greenwell AA, Yang K, Farraj RA, et al
    The Antipsychotic Dopamine 2 Receptor Antagonist Diphenylbutylpiperidines Improve Glycemia in Experimental Obesity by Inhibiting Succinyl-CoA:3-Ketoacid CoA Transferase.
    Diabetes. 2022 Oct 18. pii: 147773. doi: 10.2337/db22-0221.
    >> Share

  63. LE TH, Crouse WL, Keele GR, Holl K, et al
    Genetic Mapping of Multiple Metabolic Traits Identifies Novel Genes for Adiposity, Lipids and Insulin Secretory Capacity in Outbred Rats.
    Diabetes. 2022 Oct 11. pii: 147723. doi: 10.2337/db22-0252.
    >> Share

  64. FAN Y, Sheng S, Guo C, Qiao W, et al
    Forkhead Box i2 Transcription Factor Regulates Systemic Energy Metabolism Via Neuropeptide AgRP.
    Diabetes. 2022;71:2106-2122.
    >> Share

    September 2022
  65. LEE HH, Jeong GW, Ye BJ, Yoo EJ, et al
    TonEBP in Myeloid Cells Promotes Obesity-Induced Insulin Resistance and Inflammation Through Adipose Tissue Remodeling.
    Diabetes. 2022 Sep 28. pii: 147686. doi: 10.2337/db21-1099.
    >> Share

  66. RAMMS B, Pollow DP, Zhu H, Nora C, et al
    Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity.
    Diabetes. 2022 Sep 26. pii: 147565. doi: 10.2337/db21-1131.
    >> Share

  67. CHANDRASEKARAN S, Melhorn S, Olerich KL, Angelo B, et al
    Exposure to Gestational Diabetes Mellitus Prior to 26 Weeks is Related to The Presence of Mediobasal Hypothalamic Gliosis in Children.
    Diabetes. 2022 Sep 12. pii: 147591. doi: 10.2337/db22-0448.
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    August 2022
  68. GUSTAFSON B, Nerstedt A, Spinelli R, Beguinot F, et al
    Type 2 Diabetes, Independent of Obesity and Age, is Characterized by Senescent and Dysfunctional Mature Human Adipose Cells.
    Diabetes. 2022 Aug 25. pii: 147523. doi: 10.2337/db22-0003.
    >> Share

  69. BODUR C, Kazyken D, Huang K, Tooley AS, et al
    TBK1-mTOR Signaling Attenuates Obesity-Linked Hyperglycemia and Insulin Resistance.
    Diabetes. 2022 Aug 19. pii: 147456. doi: 10.2337/db22-0256.
    >> Share

  70. TANG Q, Liu Q, Li J, Yan J, et al
    MANF in POMC neurons promotes brown adipose tissue thermogenesis and protects against diet-induced obesity.
    Diabetes. 2022 Aug 12. pii: 147413. doi: 10.2337/db21-1128.
    >> Share

  71. BARTOLOME A, Ravusin Y, Yu J, Ferrante AW, et al
    An Overfeeding-Induced Obesity Mouse Model Reveals Necessity for Sin3a in Postnatal Peak beta Cell Mass Acquisition.
    Diabetes. 2022 Aug 9. pii: 147409. doi: 10.2337/db22-0306.
    >> Share

  72. WANG X, Cui X, Li Y, Li F, et al
    MC4R Deficiency Causes Dysregulation of Postsynaptic Excitatory Synaptic Transmission as a Crucial Culprit for Obesity.
    Diabetes. 2022 Aug 4. pii: 147382. doi: 10.2337/db22-0162.
    >> Share

  73. JO W, Kim M, Oh J, Kim CS, et al
    MicroRNA-29 Ameliorates Fibro-Inflammation and Insulin Resistance in HIF1alpha-Deficient Obese Adipose Tissue by Inhibiting Endotrophin Generation.
    Diabetes. 2022;71:1746-1762.
    >> Share

    July 2022
  74. CHEN Z, Haus JM, Chen L, Jiang Y, et al
    Inhibition of CCL28/CCR10-mediated eNOS Downregulation Improves Skin Wound Healing in the Obesity-induced Mouse Model of Type 2 Diabetes.
    Diabetes. 2022 Jul 28. pii: 147325. doi: 10.2337/db21-1108.
    >> Share

  75. KONG Q, Zou J, Zhang Z, Pan R, et al
    BAF60a Deficiency in Macrophage Promotes Diet-Induced Obesity and Metabolic Inflammation.
    Diabetes. 2022 Jul 13. pii: 147222. doi: 10.2337/db22-0114.
    >> Share

  76. SAMMS RJ, Cosgrove R, Snider BM, Furber EC, et al
    GIPR Agonism Inhibits PYY-Induced Nausea-Like Behavior.
    Diabetes. 2022;71:1410-1423.
    >> Share

  77. SUNDARESAN S, Antoun J, Banan B, Adcock J, et al
    Botulinum Injection Into the Proximal Intestinal Wall of Diet-Induced Obese Mice Leads to Weight Loss and Improves Glucose and Fat Tolerance.
    Diabetes. 2022;71:1424-1438.
    >> Share

    June 2022
  78. KUSUYAMA J, Makarewicz NS, Albertson BG, Alves-Wagner AB, et al
    Maternal Exercise-Induced SOD3 Reverses the Deleterious Effects of Maternal High-Fat Diet on Offspring Metabolism Through Stabilization of H3K4me3 and Protection Against WDR82 Carbonylation.
    Diabetes. 2022;71:1170-1181.
    >> Share

    May 2022
  79. CHAVES AB, Zheng D, Johnson JA, Bergman BC, et al
    Infant Mesenchymal Stem Cell Insulin Action is Associated With Maternal Plasma Free Fatty Acids, Independent of Obesity Status: The Healthy Start Study.
    Diabetes. 2022 May 27. pii: 147014. doi: 10.2337/db21-0812.
    >> Share

  80. GIRDHAR K, Soto M, Huang Q, Orliaguet L, et al
    Gut Microbiota Regulate Pancreatic Growth, Exocrine Function, and Gut Hormones.
    Diabetes. 2022;71:945-960.
    >> Share

    April 2022
  81. MOON JS, Riopel M, Seo JB, Herrero-Aguayo V, et al
    HIF-2alpha Preserves Mitochondrial Activity And Glucose Sensing in Compensating Beta Cells in Obesity.
    Diabetes. 2022 Apr 26. pii: 145037. doi: 10.2337/db21-0736.
    >> Share

  82. DE BRITO MONTEIRO L, Silveira Prodonoff J, Favero de Aguiar C, Correa-da-Silva F, et al
    Circulating Metabolites Associate with and Improve the Prediction of All-Cause Mortality in Type 2 Diabetes.
    Diabetes. 2022 Apr 4. pii: 144973. doi: 10.2337/db21-0842.
    >> Share

  83. KAHN DE, Bergman BC
    Keeping It Local in Metabolic Disease: Adipose Tissue Paracrine Signaling and Insulin Resistance.
    Diabetes. 2022;71:599-609.
    >> Share

    March 2022
  84. MENG D, Zhang B, Wang Y, Zheng T, et al
    p38alpha Deficiency in T Cells Ameliorates Diet-Induced Obesity, Insulin Resistance and Adipose Tissue Senescence.
    Diabetes. 2022 Mar 29. pii: 144961. doi: 10.2337/db21-0653.
    >> Share

  85. AHMED BA, Varah N, Ong FJ, Blondin DP, et al
    Impaired Cold Stimulated Supraclavicular Brown Adipose Tissue Activity in Young Boys with Obesity.
    Diabetes. 2022 Mar 16. pii: 144832. doi: 10.2337/db21-0799.
    >> Share

  86. MONJI A, Zhang Y, Kumar GVN, Guillermier C, et al
    A Cycle of Inflammatory Adipocyte Death and Regeneration in Murine Adipose Tissue.
    Diabetes. 2022;71:412-423.
    >> Share

  87. ESPINOSA DE YCAZA AE, Sondergaard E, Morgan-Bathke M, Lytle K, et al
    Adipose Tissue Inflammation Is Not Related to Adipose Insulin Resistance in Humans.
    Diabetes. 2022;71:381-393.
    >> Share

    February 2022
  88. LIU R, Pugh GH, Tevonian E, Thompson K, et al
    Regulatory T Cells Control Effector T Cell Inflammation in Human Prediabetes.
    Diabetes. 2022;71:264-274.
    >> Share

    January 2022
  89. YANG Q, Hinkle J, Reed JN, Aherrahrou R, et al
    Adipocyte-Specific Modulation of KLF14 Expression in Mice Leads to Sex-Dependent Impacts on Adiposity and Lipid Metabolism.
    Diabetes. 2022 Jan 26. pii: 140940. doi: 10.2337/db21-0674.
    >> Share

  90. SAEED S, Janjua QM, Haseeb A, Khanam R, et al
    Rare Variant Analysis of Obesity-Associated Genes in Young Adults With Severe Obesity From a Consanguineous Population of Pakistan.
    Diabetes. 2022 Jan 21. pii: 140942. doi: 10.2337/db21-0373.
    >> Share

  91. HU Q, Mu J, Liu Y, Yang Y, et al
    Obesity-Induced miR-455 Upregulation Promotes Adaptive Pancreatic beta-cell Proliferation Through the CPEB1/CDKN1B Pathway.
    Diabetes. 2022 Jan 14. pii: 139246. doi: 10.2337/db21-0134.
    >> Share

  92. LIN Y, Bai M, Wang S, Chen L, et al
    Lactate is a Key Mediator That Links Obesity to Insulin Resistance via Modulating Cytokine Production From Adipose Tissue.
    Diabetes. 2022 Jan 14. pii: 139309. doi: 10.2337/db21-0535.
    >> Share

  93. DOLLET L, Kuefner M, Caria E, Rizo-Roca D, et al
    Glutamine Regulates Skeletal Muscle Immunometabolism in Type 2 Diabetes.
    Diabetes. 2022 Jan 14. pii: 139331. doi: 10.2337/db20-0814.
    >> Share

  94. KAVAZOVIC I, Krapic M, Beumer-Chuwonpad A, Polic B, et al
    Hyperglycemia and Not Hyperinsulinemia Mediates Diabetes-Induced Memory Cd8 T Cell Dysfunction.
    Diabetes. 2022 Jan 14. pii: 139330. doi: 10.2337/db21-0209.
    >> Share

    November 2021
  95. AHMAD S, Hammar U, Kennedy B, Salihovic S, et al
    The Effect of General Adiposity and Central Body Fat Distribution on the Circulating Metabolome: a Multi-Cohort Non-Targeted Metabolomics Observational and Mendelian Randomization Study.
    Diabetes. 2021 Nov 16. pii: db20-1120. doi: 10.2337/db20-1120.
    >> Share

  96. GUO B, Liu J, Wang B, Zhang C, et al
    Withaferin A Promotes White Adipose Browning and Prevents Obesity Through Sympathetic Nerve-Activated Prdm16-FATP1 Axis.
    Diabetes. 2021 Nov 3. pii: db21-0470. doi: 10.2337/db21-0470.
    >> Share

  97. YOUSRI NA, Suhre K, Yassin E, Al-Shakaki A, et al
    Metabolic and Metabo-Clinical Signatures of T2D, Obesity, Retinopathy and Dyslipidemia.
    Diabetes. 2021 Nov 3. pii: db21-0490. doi: 10.2337/db21-0490.
    >> Share

  98. HOLST JJ
    Treatment of Type 2 Diabetes and Obesity on the Basis of the Incretin System: The 2021 Banting Medal for Scientific Achievement Award Lecture.
    Diabetes. 2021;70:2468-2475.
    >> Share

    October 2021
  99. HERZ CT, Kulterer OC, Prager M, Schmoltzer C, et al
    Active Brown Adipose Tissue is Associated With a Healthier Metabolic Phenotype in Obesity.
    Diabetes. 2021 Oct 18. pii: db21-0475. doi: 10.2337/db21-0475.
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  100. HERZ CT, Kulterer OC, Prager M, Schmoltzer C, et al
    Active Brown Adipose Tissue is Associated With a Healthier Metabolic Phenotype in Obesity.
    Diabetes. 2021 Oct 18. pii: 139093. doi: 10.2337/db21-0475.
    >> Share

  101. CEDDIA RP, Liu D, Shi F, Crowder MK, et al
    Increased Energy Expenditure and Protection from Diet-Induced Obesity in Mice Lacking the cGMP-Specific Phosphodiesterase PDE9.
    Diabetes. 2021 Oct 7. pii: db21-0100. doi: 10.2337/db21-0100.
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  102. SHIN J, Toyoda S, Nishitani S, Fukuhara A, et al
    Possible Involvement of Adipose Tissue in Older and Obese Diabetic Patients with Coronavirus SARS-CoV-2 Infection (COVID-19) via GRP78 (BIP/HSPA5): Significance of Hyperinsulinemia Management in COVID-19.
    Diabetes. 2021 Oct 6. pii: db20-1094. doi: 10.2337/db20-1094.
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  103. BEN-HAROUSH SCHYR R, Al-Kurd A, Moalem B, Permyakova A, et al
    Sleeve Gastrectomy Suppresses Hepatic Glucose Production and Increases Hepatic Insulin Clearance Independent of Weight Loss.
    Diabetes. 2021;70:2289-2298.
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  104. LI Y, Jin L, Jiang F, Yan J, et al
    Mutations of NRG4 Contribute to the Pathogenesis of Nonalcoholic Fatty Liver Disease and Related Metabolic Disorders.
    Diabetes. 2021;70:2213-2224.
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  105. JIA D, Zhang J, Liu X, Andersen JP, et al
    Insulin Resistance in Skeletal Muscle Selectively Protects the Heart in Response to Metabolic Stress.
    Diabetes. 2021;70:2333-2343.
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    September 2021
  106. AGARWAL N, Iyer D, Saha P, Cox AR, et al
    HIV-1 Viral Protein R Couples Metabolic Inflexibility With White Adipose Tissue Thermogenesis.
    Diabetes. 2021;70:2014-2025.
    >> Share

  107. HAYES MR, Borner T, De Jonghe BC
    The Role of GIP in the Regulation of GLP-1 Satiety and Nausea.
    Diabetes. 2021;70:1956-1961.
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  108. LECUYER E, Le Roy T, Gestin A, Lacombe A, et al
    Tolerogenic Dendritic Cells Shape a Transmissible Gut Microbiota That Protects From Metabolic Diseases.
    Diabetes. 2021;70:2067-2080.
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    August 2021
  109. GAO H, Zhong Y, Ding Z, Lin S, et al
    Pinch loss ameliorates obesity, glucose intolerance and fatty liver by modulating adipocyte apoptosis in mice.
    Diabetes. 2021 Aug 11. pii: db21-0392. doi: 10.2337/db21-0392.
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  110. XIU J, Han R, Liu Z, Li J, et al
    Hijacking Dorsal Raphe to Improve Metabolism and Depression-Like Behaviors via BDNF Gene Transfer in Mice.
    Diabetes. 2021;70:1780-1793.
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    July 2021
  111. KOH HE, van Vliet S, Pietka TA, Meyer GA, et al
    Subcutaneous adipose tissue metabolic function and insulin sensitivity in people with obesity.
    Diabetes. 2021 Jul 15. pii: db21-0160. doi: 10.2337/db21-0160.
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  112. MILETI E, Kwok KHM, Andersson DP, Mathelier A, et al
    Human White Adipose Tissue Displays Selective Insulin Resistance in the Obese State.
    Diabetes. 2021;70:1486-1497.
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    June 2021
  113. CHOI C, Son Y, Kim J, Cho YK, et al
    TM4SF5 knockout protects mice from diet-induced obesity partly by regulating autophagy in adipose tissue.
    Diabetes. 2021 Jun 29. pii: db21-0145. doi: 10.2337/db21-0145.
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  114. Statement of Retraction. Qilong Wang, Zhonglin Xie, Wencheng Zhang, Jun Zhou, Yue Wu, Miao Zhang, Huaiping Zhu, and Ming-Hui Zou. Myeloperoxidase Deletion Prevents High-Fat Diet-Induced Obesity and Insulin Resistance. Diabetes 2014;63:4172-4185. DOI:
    Diabetes. 2021 Jun 28. pii: db21-rt08c. doi: 10.2337.
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  115. SCHASCHKOW A, Pang L, Vandenbempt V, Elvira B, et al
    STAT3 regulates mitochondrial gene expression in pancreatic beta-cells and its deficiency induces glucose intolerance in obesity.
    Diabetes. 2021 Jun 28. pii: db20-1222. doi: 10.2337/db20-1222.
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  116. WANG Q, Zhang P, Cakir I, Mi L, et al
    Deletion of the feeding-induced hepatokine TSK ameliorates the melanocortin obesity syndrome.
    Diabetes. 2021 Jun 28. pii: db21-0161. doi: 10.2337/db21-0161.
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  117. FUKUDA M
    The role of GIP receptor in the CNS for the pathogenesis of obesity.
    Diabetes. 2021 Jun 27. pii: dbi21-0001. doi: 10.2337/dbi21-0001.
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  118. GUO Z, Zhang Y, Liu C, Youn JY, et al
    Toll-like Receptor 2 (TLR2) Deficiency Abrogates Diabetic and Obese Phenotypes while Restoring Endothelial Function via Inhibition of NOX1.
    Diabetes. 2021 Jun 14. pii: db20-0591. doi: 10.2337/db20-0591.
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  119. SEWAYBRICKER LE, Schur EA
    Is Bariatric Surgery Brain Surgery?
    Diabetes. 2021;70:1244-1246.
    >> Share

  120. ALMBY KE, Lundqvist MH, Abrahamsson N, Kvernby S, et al
    Effects of Gastric Bypass Surgery on the Brain: Simultaneous Assessment of Glucose Uptake, Blood Flow, Neural Activity, and Cognitive Function During Normo- and Hypoglycemia.
    Diabetes. 2021;70:1265-1277.
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    May 2021
  121. CHOI S, Choi D, Lee YK, Ahn SH, et al
    Depletion of Prmt1 in adipocytes impairs glucose homeostasis in diet-induced obesity.
    Diabetes. 2021 May 26. pii: db20-1050. doi: 10.2337/db20-1050.
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  122. DONG SS, Zhu DL, Zhou XR, Rong Y, et al
    An intronic risk SNP rs12454712 for central obesity acts as an allele-specific enhancer to regulate BCL2 expression.
    Diabetes. 2021 May 25. pii: db20-1151. doi: 10.2337/db20-1151.
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  123. MARTIN S, Cule M, Basty N, Tyrrell J, et al
    Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease.
    Diabetes. 2021 May 12. pii: db21-0129. doi: 10.2337/db21-0129.
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    April 2021
  124. GONCALVES GHM, Trist O SM, Volpi RE, Almeida-Pereira G, et al
    STAT3 but not ERK2 is a Crucial Mediator against Diet-Induced Obesity via VMH neurons.
    Diabetes. 2021 Apr 21. pii: db20-0658. doi: 10.2337/db20-0658.
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  125. PENG WQ, Xiao G, Li BY, Guo YY, et al
    L-Theanine Activates the Browning of White Adipose Tissue through the AMPK/alpha-Ketoglutarate/Prdm16 Axis and Ameliorates Diet-induced Obesity in Mice.
    Diabetes. 2021 Apr 16. pii: db20-1210. doi: 10.2337/db20-1210.
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  126. SANCHEZ-DELGADO G, Martinez-Tellez B, Acosta FM, Virtue S, et al
    Brown Adipose Tissue Volume and Fat Content are Positively Associated with Whole-Body Adiposity in Young Men, Not in Women.
    Diabetes. 2021 Apr 15. pii: db21-0011. doi: 10.2337/db21-0011.
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  127. DESOYE G, Wells JCK
    Pregnancies in Diabetes and Obesity: The Capacity-Load Model of Placental Adaptation.
    Diabetes. 2021;70:823-830.
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    March 2021
  128. ANTONY A, Lian Z, Perrard XD, Perrard J, et al
    Deficiency of Stat1 in CD11c(+) Cells Alters Adipose Tissue Inflammation and Improves Metabolic Dysfunctions in Mice Fed a High-Fat Diet.
    Diabetes. 2021;70:720-732.
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    February 2021
  129. SHARIF O, Brunner JS, Korosec A, Martins R, et al
    Beneficial Metabolic Effects of TREM2 in Obesity are Uncoupled from its Expression on Macrophages.
    Diabetes. 2021 Feb 24. pii: db20-0572. doi: 10.2337/db20-0572.
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  130. CAO P, Song Y, Zhuang Z, Ran J, et al
    Obesity and COVID-19 in Adult Patients With Diabetes.
    Diabetes. 2021 Feb 17. pii: db20-0671. doi: 10.2337/db20-0671.
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  131. KANG S
    Adipose Tissue Malfunction Drives Metabolic Dysfunction in Alstrom Syndrome.
    Diabetes. 2021;70:323-325.
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  132. BRAUNE J, Lindhorst A, Froba J, Hobusch C, et al
    Multinucleated Giant Cells in Adipose Tissue Are Specialized in Adipocyte Degradation.
    Diabetes. 2021;70:538-548.
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  133. GASTALDELLI A, Abdul Ghani M, DeFronzo RA
    Adaptation of Insulin Clearance to Metabolic Demand Is a Key Determinant of Glucose Tolerance.
    Diabetes. 2021;70:377-385.
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    January 2021
  134. JONSSON J, Renault KM, Garcia-Calzon S, Perfilyev A, et al
    Lifestyle Intervention in Pregnant Women With Obesity Impacts Cord Blood DNA Methylation Which Associates With Body Composition in the Offspring.
    Diabetes. 2021 Jan 11. pii: db20-0487. doi: 10.2337/db20-0487.
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  135. JERSIN RA, Priyanka Tallapragada DS, Madsen A, Skartveit L, et al
    Role of the Neutral Amino Acid Transporter Slc7a10 in Adipocyte Lipid Storage, Obesity and Insulin Resistance.
    Diabetes. 2021 Jan 6. pii: db20-0096. doi: 10.2337/db20-0096.
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  136. MING X, Chung ACK, Mao D, Cao H, et al
    Pancreatic Sirtuin 3 Deficiency Promotes Hepatic Steatosis by Enhancing 5-Hydroxytryptamine Synthesis in Mice With Diet-Induced Obesity.
    Diabetes. 2021;70:119-131.
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  137. MALBERT CH, Chauvin A, Horowitz M, Jones KL, et al
    Glucose Sensing Mediated by Portal Glucagon-Like Peptide 1 Receptor Is Markedly Impaired in Insulin-Resistant Obese Animals.
    Diabetes. 2021;70:99-110.
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    December 2020
  138. SEOK S, Sun H, Kim YC, Kemper B, et al
    Defective FXR-SHP Regulation in Obesity Aberrantly Increases miR-802 Expression, Promoting Insulin Resistance and Fatty Liver.
    Diabetes. 2020 Dec 16. pii: db20-0856. doi: 10.2337/db20-0856.
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  139. SEONG HA, Ha H
    Ablation of AMPK-Related Kinase MPK38/MELK Leads to Male-Specific Obesity in Aged Mature Adult Mice.
    Diabetes. 2020 Dec 2. pii: db20-0436. doi: 10.2337/db20-0436.
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  140. MARTCHENKO SE, Martchenko A, Cox BJ, Naismith K, et al
    Circadian GLP-1 Secretion in Mice Is Dependent on the Intestinal Microbiome for Maintenance of Diurnal Metabolic Homeostasis.
    Diabetes. 2020;69:2589-2602.
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    November 2020
  141. COTE JL, Argetsinger LS, Flores A, Rupp AC, et al
    Deletion of the Brain-Specific alpha and delta Isoforms of Adapter Protein SH2B1 Protects Mice From Obesity.
    Diabetes. 2020 Nov 19. pii: db20-0687. doi: 10.2337/db20-0687.
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  142. HUANG R, Bai X, Li X, Wang X, et al
    Retinol-Binding Protein 4 Activates STRA6 Provoking Pancreatic beta Cell Dysfunction in Type 2 Diabetes.
    Diabetes. 2020 Nov 16. pii: db19-1241. doi: 10.2337/db19-1241.
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  143. ZIZZARI P, He R, Falk S, Bellocchio L, et al
    CB1 and GLP-1 Receptors Cross-Talk Provides New Therapies for Obesity.
    Diabetes. 2020 Nov 3. pii: db20-0162. doi: 10.2337/db20-0162.
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  144. GAMBLIN C, Rouault C, Lacombe A, Langa-Vives F, et al
    Lysosomal Acid Lipase Drives Adipocyte Cholesterol Homeostasis and Modulates Lipid Storage in Obesity, Independent of Autophagy.
    Diabetes. 2020 Nov 2. pii: db20-0578. doi: 10.2337/db20-0578.
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  145. WANG G, Yu Y, Cai W, Batista TM, et al
    Muscle-Specific Insulin Receptor Overexpression Protects Mice From Diet-Induced Glucose Intolerance but Leads to Postreceptor Insulin Resistance.
    Diabetes. 2020;69:2294-2309.
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  146. SAKANO D, Uefune F, Tokuma H, Sonoda Y, et al
    VMAT2 Safeguards beta-Cells Against Dopamine Cytotoxicity Under High-Fat Diet-Induced Stress.
    Diabetes. 2020;69:2377-2391.
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  147. TOKUMOTO S, Yabe D, Tatsuoka H, Usui R, et al
    Generation and Characterization of a Novel Mouse Model That Allows Spatiotemporal Quantification of Pancreatic beta-Cell Proliferation.
    Diabetes. 2020;69:2340-2351.
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    October 2020
  148. RAKSHIT K, Matveyenko AV
    Induction of Core Circadian Clock Transcription Factor Bmal1 Enhances beta Cell Function and Protects Against Obesity-Induced Glucose Intolerance.
    Diabetes. 2020 Oct 21. pii: db20-0192. doi: 10.2337/db20-0192.
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  149. KOTHARI V, Bornfeldt KE
    A New Treatment Strategy for Diabetic Dyslipidemia?
    Diabetes. 2020;69:2061-2063.
    >> Share

    September 2020
  150. GEBERHIWOT T, Baig S, Obringer C, Girard D, et al
    Relative Adipose Tissue Failure in Alstrom Syndrome Drives Obesity-Induced Insulin Resistance.
    Diabetes. 2020 Sep 29. pii: db20-0647. doi: 10.2337/db20-0647.
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  151. COX AR, Chernis N, Bader DA, Saha PK, et al
    STAT1 Dissociates Adipose Tissue Inflammation From Insulin Sensitivity in Obesity.
    Diabetes. 2020 Sep 29. pii: db20-0384. doi: 10.2337/db20-0384.
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  152. HERZOG K, Berggren J, Al Majdoub M, Balderas Arroyo C, et al
    Metabolic Effects of Gastric Bypass Surgery: Is It All About Calories?
    Diabetes. 2020;69:2027-2035.
    >> Share

  153. NIKPAY M, Lau P, Soubeyrand S, Whytock KL, et al
    SGCG rs679482 Associates With Weight Loss Success in Response to an Intensively Supervised Outpatient Program.
    Diabetes. 2020;69:2017-2026.
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    June 2020
  154. SUPPLI MP, Bagger JI, Lund A, Demant M, et al
    Glucagon Resistance at the Level of Amino Acid Turnover in Obese Subjects With Hepatic Steatosis.
    Diabetes. 2020;69:1090-1099.
    >> Share

    May 2020
  155. ZHAO S, Kusminski CM, Elmquist JK, Scherer PE, et al
    Leptin: Less Is More.
    Diabetes. 2020;69:823-829.
    >> Share


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