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Malignant Melanoma

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Articles published in
Am J Dermatopathol
    August 2025
  1. REGMI A, Parra O, Ma W, LeBlanc RE, et al
    Evaluating the Diagnostic Concordance of MyPath Melanoma Assay and PRAME Immunohistochemistry in Challenging Melanocytic Lesions.
    Am J Dermatopathol. 2025 Aug 28. doi: 10.1097/DAD.0000000000003018.
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  2. HIRAI I, Walker JL, Rubin AI, Chu EY, et al
    CRTC1::TRIM11 Cutaneous Tumor Mimicking Primary Dermal Melanoma: Case Report With Literature Review.
    Am J Dermatopathol. 2025 Aug 26. doi: 10.1097/DAD.0000000000003108.
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  3. ZOU Y, Li L, Xia R, Wang F, et al
    Accuracy of Confocal Microscopy for the Diagnosis of Acral Lentiginous Melanoma and Acral Melanocytic Nevi.
    Am J Dermatopathol. 2025 Aug 6. doi: 10.1097/DAD.0000000000003099.
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  4. ADDO AK, Beydoun HM, Jeyakumar JE, Olivares S, et al
    The Morphologic Spectrum of NF Mutated Desmoplastic Melanocytic Neoplasms.
    Am J Dermatopathol. 2025 Aug 6. doi: 10.1097/DAD.0000000000003056.
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    July 2025
  5. HARRIS MS, Castaneda C, Wieland A, Bennett DD, et al
    Malignant Melanoma With Transdifferentiation Into a Ganglioneuroblastic Phenotype After Anti-PD-1 Therapy.
    Am J Dermatopathol. 2025 Jul 28. doi: 10.1097/DAD.0000000000003080.
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    June 2025
  6. CHO WC, Yang RK, Lenskaya V, Prieto VG, et al
    SBF1::BRAF-Fused Melanoma With Prominent Rhabdoid Morphology and Reed-Sternberg-Like Cells: Potential Morphologic Clues to BRAF-Fused Melanomas of Non-Spitz Lineage?
    Am J Dermatopathol. 2025 Jun 26. doi: 10.1097/DAD.0000000000003048.
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  7. URSO C
    Primary Cutaneous Melanoma With Sebocyte-like Melanocytes: Case Report and Review of the Literature.
    Am J Dermatopathol. 2025 Jun 26. doi: 10.1097/DAD.0000000000003007.
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  8. MUJEB A, Paez-Garcia MS, Musolff N, Tchack M, et al
    Significance of Sectioning (Breadloafing) the Entire Skin Tissue When Pathology Does Not Match Clinical Appearance.
    Am J Dermatopathol. 2025 Jun 26. doi: 10.1097/DAD.0000000000003046.
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  9. MEIJS-HERMANNS PR, Spitzer-Naaijkens JMJ, Kester LA, Jansen AML, et al
    A Stranger in the Slide: A Rare Collision of a Spitz Melanocytoma With a Novel MYH9::LTK Fusion and a Common BRAF Mutated Nevus Mimicking a Melanoma With a Preexistent Nevus.
    Am J Dermatopathol. 2025 Jun 25. doi: 10.1097/DAD.0000000000003039.
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  10. SCHIRWANI S, Theaker J, Side L, Moutasim K, et al
    Atypical Spitz Tumor (Spitz Melanocytoma) With Lymph Node Metastasis and Long-Term Clinical Follow-Up.
    Am J Dermatopathol. 2025 Jun 23. doi: 10.1097/DAD.0000000000002982.
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  11. KUNZLER E, Enos C, Bohannon M, Walker A, et al
    The University of Florida Dermatopathology Experience With the Pigmented Lesion Assay.
    Am J Dermatopathol. 2025;47:468-471.
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    April 2025
  12. VAVRUKH P, LeBlanc RE, Yan S
    Diagnostic Utility of Preferentially Expressed Antigen in Melanoma (PRAME) and p16 Immunohistochemistry in Distinguishing Genital Melanomas From Benign Melanocytic Proliferations.
    Am J Dermatopathol. 2025 Apr 22. doi: 10.1097/DAD.0000000000002977.
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    March 2025
  13. SHAKER N, Niu S, Blankenship H, Shaker N, et al
    Artificial Intelligence and Convolutional Neural Networks-Driven Detection of Micro and Macro Metastasis of Cutaneous Melanoma to the Lymph Nodes.
    Am J Dermatopathol. 2025 Mar 19. doi: 10.1097/DAD.0000000000002954.
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    February 2025
  14. GAO Y, Yang RK, Curry JL, Torres-Cabala CA, et al
    Melanoma With RNF11::BRAF Fusion: A Novel Fusion Previously Undescribed in Melanoma.
    Am J Dermatopathol. 2025 Feb 25. doi: 10.1097/DAD.0000000000002936.
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  15. KOGA S, Karakousis GC, Yang G, Elder DE, et al
    Late Recurrent Spitz Melanoma With a TMEM106B::BRAF Fusion.
    Am J Dermatopathol. 2025 Feb 19. doi: 10.1097/DAD.0000000000002946.
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  16. SHAKER N, Phelps R, Niedt G, Sangueza O, et al
    BRCA1-Associated Protein-1 Inactivated Melanoma Arising in a Pre-existing Nevus With ALK Fusion and Low Tumor Mutational Burden.
    Am J Dermatopathol. 2025 Feb 6. doi: 10.1097/DAD.0000000000002925.
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  17. KNITTEL RJ, Harvey NT, Ardakani NM, O'Brien B, et al
    Clinicopathologic Features of PRAME-Positive Common Melanocytic Nevi: A Case-Control Study.
    Am J Dermatopathol. 2025 Feb 6. doi: 10.1097/DAD.0000000000002932.
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    December 2024
  18. TIRUMALAE R, Correa M, Manjunath S
    Intramuscular Cellular Nodules in a Congenital Large Plaque-Like Blue Nevus: Melanoma or Not?
    Am J Dermatopathol. 2024 Dec 31. doi: 10.1097/DAD.0000000000002906.
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  19. FERNANDEZ-FLORES A
    "Pathway Leap": A New Molecular Phenomenon to Consider in the Pathogenesis of Melanocytic Tumors.
    Am J Dermatopathol. 2024 Dec 31. doi: 10.1097/DAD.0000000000002916.
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  20. YAVUZ A, Simsek K, Bassorgun CI, Elpek GO, et al
    The Prognostic Significance of Tumor Budding and Tumor-Infiltrating Lymphocytes in Patients Diagnosed With Malignant Melanoma.
    Am J Dermatopathol. 2024 Dec 10. doi: 10.1097/DAD.0000000000002902.
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    November 2024
  21. MACHUCA-AGUADO J, Lopez-Prieto A, Mora-Diaz R, Gutierrez-Domingo A, et al
    PRAME Immunostaining in BAP-1-Inactivated Melanocytic Tumors: Unraveling Diagnostic Complexity and Exploring Germline Mutation Associations.
    Am J Dermatopathol. 2024 Nov 7. doi: 10.1097/DAD.0000000000002717.
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    October 2024
  22. FERNANDEZ-FLORES A
    Selective Clonal Regression After Interferon Therapy in Metastatic Melanoma.
    Am J Dermatopathol. 2024 Oct 31. doi: 10.1097/DAD.0000000000002873.
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  23. KOSSARD S, Sharifi S, Calvey L
    Utilizing PRAME Expression and a Meta-Analytic Framework for iSALT to Explore Atypical Late-Onset Nevi of the Elderly and Their Relationship With Lentiginous and Nested Nevoid Melanomas.
    Am J Dermatopathol. 2024 Oct 15. doi: 10.1097/DAD.0000000000002847.
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  24. ASATO MA, Moraes Neto FA, Moraes MPT, Ocanha-Xavier JP, et al
    The Utility of PRAME and Ki-67 as Prognostic Markers for Cutaneous Melanoma.
    Am J Dermatopathol. 2024 Oct 15. doi: 10.1097/DAD.0000000000002863.
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    September 2024
  25. DARUISH M, Kerr G, Taibjee S
    A Combined Spindle Cell Melanoma and Sarcomatoid Squamous Cell Carcinoma: A Rather Unique Squamomelanocytic Tumor.
    Am J Dermatopathol. 2024 Sep 17. doi: 10.1097/DAD.0000000000002838.
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  26. SINGH P, Wu D, Karunamurthy A, Seynnaeve BKN, et al
    Pediatric Melanoma With a Rare BRAF V600K Mutation.
    Am J Dermatopathol. 2024 Sep 17. doi: 10.1097/DAD.0000000000002835.
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  27. RUZ PORTERO B, Garcia de Sola Llamas C, Perez Perez M, Sanchez Bernal ML, et al
    Cellular Schwannoma Mimicking a Nodular Melanoma on the Sole of the Foot, an Avoidable Diagnostic Pitfall.
    Am J Dermatopathol. 2024;46:e79-e83.
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    August 2024
  28. VAN SAMBEEK S, Friedlander E, Patino WD
    A Retrospective Review: Our Experience With an Adhesive-Based Pigmented Lesion Assay Used to Evaluate Cutaneous Lesions Suspicious for Melanoma.
    Am J Dermatopathol. 2024 Aug 14. doi: 10.1097/DAD.0000000000002759.
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  29. DARUISH M, Karunaratne S, Duffy-Gadd P, Hansford S, et al
    Utility of PRAME Immunohistochemistry in the Detection of Subtle Melanoma Microsatellites.
    Am J Dermatopathol. 2024 Aug 14. doi: 10.1097/DAD.0000000000002817.
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  30. NG S, Hall KC, Busam KJ, Lezcano C, et al
    Superficial Wnt-Activated Melanocytic Nevi/Melanocytomas With a Junctional Component: A Case Series.
    Am J Dermatopathol. 2024 Aug 14. doi: 10.1097/DAD.0000000000002804.
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  31. GOLDBERG MS, Cockerell CJ, Rogers JH, Siegel JJ, et al
    Appropriate Statistical Methods to Assess Cross-study Diagnostic 23-Gene Expression Profile Test Performance for Cutaneous Melanocytic Neoplasms.
    Am J Dermatopathol. 2024 Aug 14. doi: 10.1097/DAD.0000000000002808.
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    July 2024
  32. FIELDS BC, Jain AJ, Prieto VG, Frink SJ, et al
    Pigmented Villonodular Synovitis: A Metastatic Melanoma Imitator.
    Am J Dermatopathol. 2024 Jul 12. doi: 10.1097/DAD.0000000000002771.
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  33. IBRAHIM E, Yang RK, Curry JL, Cho WC, et al
    BCR::ZNF711 and BCR::CYLC2 Fusions: Novel BCR Fusions Expanding the Molecular Spectrum of Gene Fusions in Melanoma.
    Am J Dermatopathol. 2024 Jul 12. doi: 10.1097/DAD.0000000000002796.
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    June 2024
  34. CHO WC, Prieto VG, Yang RK
    Spitz Melanoma With SLC20A1::ALK Fusion: A Novel Fusion Previously Undescribed in Spitz Melanocytic Neoplasm.
    Am J Dermatopathol. 2024 Jun 28. doi: 10.1097/DAD.0000000000002778.
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  35. CHEN JM, Hernandez E, Frosina D, Ruh PA, et al
    In Situ Protein Expression Analysis of Melanocyte Differentiation Antigen TRP1 (Tyrosinase-Related Protein-1).
    Am J Dermatopathol. 2024 Jun 28. doi: 10.1097/DAD.0000000000002772.
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  36. MERT M, Bozdogan O, Bozdogan N, Gamsizkan M, et al
    PRAME and Historical Immunohistochemical Antibodies Ki-67, P16, and HMB-45 in Ambiguous Melanocytic Tumors.
    Am J Dermatopathol. 2024 Jun 20. doi: 10.1097/DAD.0000000000002768.
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  37. KNITTEL R, Rogers S, Wood BA
    Cutaneous Seeding of Glioblastoma: A Case Report and Literature Review.
    Am J Dermatopathol. 2024 Jun 6. doi: 10.1097/DAD.0000000000002748.
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    May 2024
  38. LEDESMA DA, Marques-Piubelli ML, Li-Ning-Tapia E, Hudgens C, et al
    Apoptosis Pathway-Associated Proteins Are Frequently Expressed in Melanoma: A Study of 32 Cases With Focus on Acral Lentiginous Melanoma.
    Am J Dermatopathol. 2024 May 7. doi: 10.1097/DAD.0000000000002635.
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  39. SU S, Liu J, Jiang Y
    Rare Presentation of Melanoma Recurrences With Diffuse Subcutaneous Intravascular Lesions: A Novel In-Transit Metastases Pattern.
    Am J Dermatopathol. 2024 May 7. doi: 10.1097/DAD.0000000000002735.
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    April 2024
  40. SRIVATSA S, Smith CJ, Sangueza OP, Miedema J, et al
    Lymphangitic Melanomatosis: Case Report of Intralymphatic Spread of Melanoma in a 66-year-old Man.
    Am J Dermatopathol. 2024 Apr 4. doi: 10.1097/DAD.0000000000002696.
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    March 2024
  41. LOPER R, Schon MP, Mitteldorf C
    Melanocyte Density in the Diagnosis of Melanoma In Situ in Sun-Damaged Skin.
    Am J Dermatopathol. 2024 Mar 19. doi: 10.1097/DAD.0000000000002680.
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  42. CASILLAS AC, Muhlbauer A, Barragan VA, Jefferson I, et al
    A Comparison of Preferentially Expressed Antigen in Melanoma Immunohistochemistry and Diagnostic Gene Expression-Profiling Assay in Challenging Melanocytic Proliferations.
    Am J Dermatopathol. 2024;46:137-146.
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  43. LOHMAN ME, Kim YH, Steen AJ, Demer AM, et al
    The Promise and Pitfalls of PRAME Immunohistochemistry During Mohs Surgery: Early Findings.
    Am J Dermatopathol. 2024;46:191-192.
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    February 2024
  44. MACHUCA-AGUADO J, Garcia-Trevijano CI, Orrego-Pereira C, Montana-Ramirez AM, et al
    Unraveling PRAME Expression in Desmoplastic Melanocytic Neoplasms: Illuminating its Diagnostic Significance in Distinguishing Desmoplastic Spitz Nevi.
    Am J Dermatopathol. 2024 Feb 7. doi: 10.1097/DAD.0000000000002638.
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    January 2024
  45. WILLS A, Dibbern M, Frierson HF, Raghavan SS, et al
    Metastatic Undifferentiated Melanoma Mimicking a Primary Bone Tumor: A Potential Diagnostic Pitfall.
    Am J Dermatopathol. 2024 Jan 3. doi: 10.1097/DAD.0000000000002622.
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    December 2023
  46. MCTIGHE SP, Taylor EA, Allbritton J, Lewin-Smith MR, et al
    Localized Cutaneous Argyria at the Site of a Prior Melanoma Excision Confirmed by Scanning Electron Microscopy With Energy Dispersive X-ray Analysis.
    Am J Dermatopathol. 2023 Dec 26. doi: 10.1097/DAD.0000000000002610.
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    November 2023
  47. NEIMY H, Helmy JE, Snyder A, Valdebran M, et al
    Artificial Intelligence in Melanoma Dermatopathology: A Review of Literature.
    Am J Dermatopathol. 2023 Nov 14. doi: 10.1097/DAD.0000000000002593.
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  48. KENNY MG, Nguyen M, Modi M, Eilers D, et al
    Melanoma Mimicker: Pigmented Mammary Paget Disease in a Man.
    Am J Dermatopathol. 2023 Nov 14. doi: 10.1097/DAD.0000000000002588.
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  49. TURNER N, Ko CJ, McNiff JM, Galan A, et al
    Pitfalls of PRAME Immunohistochemistry in a Large Series of Melanocytic and Nonmelanocytic Lesions With Literature Review.
    Am J Dermatopathol. 2023 Nov 14. doi: 10.1097/DAD.0000000000002584.
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  50. DONATI M, Grossmann P, Mansour B, Kazakov DV, et al
    Melanocytic Neoplasm With KIT and APC Mutations: A New Subtype of Melanocytoma?
    Am J Dermatopathol. 2023 Nov 14. doi: 10.1097/DAD.0000000000002556.
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  51. KIM JC, Choi JW, Kim YC
    Comparison of Melanocyte-Associated Immunohistochemical Markers in Acral Lentiginous Melanoma and Acral Benign Nevi.
    Am J Dermatopathol. 2023;45:748-752.
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  52. LEZCANO C, Jungbluth AA, Busam KJ
    Immunohistochemistry for PRAME in Dermatopathology.
    Am J Dermatopathol. 2023;45:733-747.
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    August 2023
  53. VANDERBECK K, Rothrock AT, Cho WC, Nagarajan P, et al
    PRAME and LEF1 in Combined Deep Penetrating Nevus and Combined Blue Nevus: Utility and Pitfalls.
    Am J Dermatopathol. 2023;45:549-556.
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  54. WEN D, Chen T, Martin RCW
    A Rare Case of a Basomelanocytic Tumor.
    Am J Dermatopathol. 2023;45:e64-e67.
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    July 2023
  55. OCANHA XAVIER JP, Xavier JCC Jr, da Silva MG, Marques MEA, et al
    Vitamin D Receptor and Retinoid X Receptor Alpha in Melanocytic Benign Lesions and Melanoma.
    Am J Dermatopathol. 2023 Jul 28. doi: 10.1097/DAD.0000000000002507.
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  56. SHERIDAN C, O'Connor MC, Sitton B, Bass J, et al
    Nevus Spilus With Dermatoheliosis: A Histologic Mimicker of Melanoma in Situ at Melanoma Excision Margins.
    Am J Dermatopathol. 2023 Jul 11. doi: 10.1097/DAD.0000000000002493.
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  57. BOUTKO A, Hagstrom M, Lampley N, Roth A, et al
    PRAME Immunohistochemical Expression and TERT Promoter Mutational Analysis as Ancillary Diagnostic Tools for Differentiating Proliferative Nodules From Melanoma Arising in Congenital Nevi.
    Am J Dermatopathol. 2023;45:437-447.
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    May 2023
  58. O'NEILL P, Amanuel B, Mesbah Ardakani N
    Cutaneous Malignant Melanoma With Rhabdomyosarcomatous Dedifferentiation: an Immunohistological and Molecular Case Study With Literature Review.
    Am J Dermatopathol. 2023 May 2. doi: 10.1097/DAD.0000000000002451.
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  59. MCFADDEN JR, Syku M, Barney RE, Stevanovic M, et al
    A Novel Method to Detect Copy Number Variation in Melanoma: Droplet Digital PCR for Quantitation of the CDKN2A Gene, a Proof-of-Concept Study.
    Am J Dermatopathol. 2023 May 2. doi: 10.1097/DAD.0000000000002436.
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    April 2023
  60. PISANI D, Micallef D, Scerri J, Betts A, et al
    Neuroendocrine Transdifferentiation in Cutaneous Melanoma: A Case Report and Review of the Literature.
    Am J Dermatopathol. 2023;45:264-268.
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  61. CORTEZ DE ALMEIDA RF, Sponchiado Assoni A, Cabrera Pereira JP, Erthal de Britto Pereira Kassuga Roisman L, et al
    Pigmented Bowen Disease in the Acral Region: A Diagnostic Challenge.
    Am J Dermatopathol. 2023;45:235-236.
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    March 2023
  62. MCFADDEN JR, Chaudhari AS, Stevanovic M, Tsongalis GJ, et al
    Gain of CCND1 May Occur Too Infrequently in Cutaneous Melanoma, and Too Late in Melanomagenesis, to Be Diagnostically Useful: Genomic Analysis of 88 Cases.
    Am J Dermatopathol. 2023 Mar 20. doi: 10.1097/DAD.0000000000002420.
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    February 2023
  63. BOUTKO A, Asadbeigi S, Roth A, Lampley N, et al
    TERT Promoter Mutational Analysis as an Ancillary Diagnostic Tool for Diagnostically Challenging Melanocytic Neoplasms.
    Am J Dermatopathol. 2023 Feb 17. doi: 10.1097/DAD.0000000000002366.
    >> Share


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