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Articles published in
Cancer Cell
    March 2024
  1. HU F, Lito P
    Insights into how adeno-squamous transition drives KRAS inhibitor resistance.
    Cancer Cell. 2024;42:330-332.
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  2. HE XY, Gao Y, Ng D, Michalopoulou E, et al
    Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment.
    Cancer Cell. 2024;42:474-486.
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    February 2024
  3. TONG X, Patel AS, Kim E, Li H, et al
    Adeno-to-squamous transition drives resistance to KRAS inhibition in LKB1 mutant lung cancer.
    Cancer Cell. 2024 Feb 20:S1535-6108(24)00036-9. doi: 10.1016/j.ccell.2024.
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  4. LIU NN, Yi CX, Wei LQ, Zhou JA, et al
    The intratumor mycobiome promotes lung cancer progression via myeloid-derived suppressor cells.
    Cancer Cell. 2024;42:318-322.
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  5. HUANG DD, Yang JC
    Re-inventing a better wheel? Serplulimab for squamous cell lung cancer.
    Cancer Cell. 2024;42:172-174.
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  6. BENGUIGUI M, Cooper TJ, Kalkar P, Schif-Zuck S, et al
    Interferon-stimulated neutrophils as a predictor of immunotherapy response.
    Cancer Cell. 2024;42:253-265.
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  7. NABET BY, Hamidi H, Lee MC, Banchereau R, et al
    Immune heterogeneity in small-cell lung cancer and vulnerability to immune checkpoint blockade.
    Cancer Cell. 2024 Feb 9:S1535-6108(24)00015-1. doi: 10.1016/j.ccell.2024.
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    January 2024
  8. HEEKE S, Gay CM, Estecio MR, Tran H, et al
    Tumor- and circulating-free DNA methylation identifies clinically relevant small cell lung cancer subtypes.
    Cancer Cell. 2024 Jan 24:S1535-6108(24)00006-0. doi: 10.1016/j.ccell.2024.
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  9. MEMON D, Schoenfeld AJ, Ye D, Fromm G, et al
    Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer.
    Cancer Cell. 2024 Jan 9:S1535-6108(23)00441-5. doi: 10.1016/j.ccell.2023.
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  10. CORDS L, Engler S, Haberecker M, Ruschoff JH, et al
    Cancer-associated fibroblast phenotypes are associated with patient outcome in non-small cell lung cancer.
    Cancer Cell. 2024 Jan 8:S1535-6108(23)00449-X. doi: 10.1016/j.ccell.2023.
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    December 2023
  11. ZHOU C, Hu Y, Arkania E, Kilickap S, et al
    A global phase 3 study of serplulimab plus chemotherapy as first-line treatment for advanced squamous non-small-cell lung cancer (ASTRUM-004).
    Cancer Cell. 2023 Dec 21:S1535-6108(23)00432-4. doi: 10.1016/j.ccell.2023.
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  12. DAYTON TL, Alcala N, Moonen L, den Hartigh L, et al
    Druggable growth dependencies and tumor evolution analysis in patient-derived organoids of neuroendocrine neoplasms from multiple body sites.
    Cancer Cell. 2023;41:2083-2099.
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  13. GERSTBERGER S, Ganesh K
    NEN in a dish: A patient-derived organoid biobank illuminates potential novel therapeutic opportunities for neuroendocrine neoplasms.
    Cancer Cell. 2023;41:2014-2016.
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  14. CHEN CC, Tran W, Song K, Sugimoto T, et al
    Temporal evolution reveals bifurcated lineages in aggressive neuroendocrine small cell prostate cancer trans-differentiation.
    Cancer Cell. 2023;41:2066-2082.
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    November 2023
  15. JIAGGE E, Jin DX, Newberg JY, Perea-Chamblee T, et al
    Tumor sequencing of African ancestry reveals differences in clinically relevant alterations across common cancers.
    Cancer Cell. 2023;41:1963-1971.
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  16. RAHAL Z, Kadara H
    Beyond bacteria: How the intratumor mycobiome modulates lung adenocarcinoma progression.
    Cancer Cell. 2023;41:1846-1848.
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    October 2023
  17. RODILLA AM, Valanparambil RM, Mack PC, Hsu CY, et al
    Longitudinal nucleocapsid antibody testing reveals undocumented SARS-CoV-2 infections in patients with lung cancer.
    Cancer Cell. 2023 Oct 13:S1535-6108(23)00350-1. doi: 10.1016/j.ccell.2023.
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  18. PAN Y, Zhang JT, Gao X, Chen ZY, et al
    Dynamic circulating tumor DNA during chemoradiotherapy predicts clinical outcomes for locally advanced non-small cell lung cancer patients.
    Cancer Cell. 2023;41:1763-1773.
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  19. LI Z, Lu S
    Integrating minimal residual disease monitoring into clinical practice for NSCLC: Is the era upon us?
    Cancer Cell. 2023;41:1699-1701.
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    September 2023
  20. ZHU M, Kim J, Deng Q, Ricciuti B, et al
    Loss of p53 and mutational heterogeneity drives immune resistance in an autochthonous mouse lung cancer model with high tumor mutational burden.
    Cancer Cell. 2023 Sep 26:S1535-6108(23)00322-7. doi: 10.1016/j.ccell.2023.
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  21. LIU NN, Yi CX, Wei LQ, Zhou JA, et al
    The intratumor mycobiome promotes lung cancer progression via myeloid-derived suppressor cells.
    Cancer Cell. 2023 Sep 19:S1535-6108(23)00288-X. doi: 10.1016/j.ccell.2023.
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  22. TOPP BG, Channavazzala M, Mayawala K, De Alwis DP, et al
    Tumor dynamics in patients with solid tumors treated with pembrolizumab beyond disease progression.
    Cancer Cell. 2023;41:1680-1688.
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  23. MEGYESFALVI Z, Heeke S, Drapkin BJ, Solta A, et al
    Unfolding the secrets of small cell lung cancer progression: Novel approaches and insights through rapid autopsies.
    Cancer Cell. 2023;41:1535-1540.
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  24. CHEN K, Yang F, Shen H, Wang C, et al
    Individualized tumor-informed circulating tumor DNA analysis for postoperative monitoring of non-small cell lung cancer.
    Cancer Cell. 2023 Sep 1:S1535-6108(23)00286-6. doi: 10.1016/j.ccell.2023.
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    August 2023
  25. HUANG Q, Liu L, Xiao D, Huang Z, et al
    CD44(+) lung cancer stem cell-derived pericyte-like cells cause brain metastases through GPR124-enhanced trans-endothelial migration.
    Cancer Cell. 2023 Aug 9:S1535-6108(23)00252-0. doi: 10.1016/j.ccell.2023.
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  26. DE MIGUEL FJ, Gentile C, Feng WW, Silva SJ, et al
    Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer.
    Cancer Cell. 2023 Aug 2:S1535-6108(23)00245-3. doi: 10.1016/j.ccell.2023.
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    July 2023
  27. QIAN Y, Galan-Cobo A, Guijarro I, Dang M, et al
    MCT4-dependent lactate secretion suppresses antitumor immunity in LKB1-deficient lung adenocarcinoma.
    Cancer Cell. 2023;41:1363-1380.
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  28. PRIETO LI, Sturmlechner I, Graves SI, Zhang C, et al
    Senescent alveolar macrophages promote early-stage lung tumorigenesis.
    Cancer Cell. 2023;41:1261-1275.
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    June 2023
  29. MA BBY, Thu Le Q
    Hot on the trail in the TME: Clues from a trilogy of checkpoint inhibitor trials in nasopharyngeal cancer.
    Cancer Cell. 2023;41:1006-1008.
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    May 2023
  30. HASTON S, Gonzalez-Gualda E, Morsli S, Ge J, et al
    Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer.
    Cancer Cell. 2023 May 26:S1535-6108(23)00172-1. doi: 10.1016/j.ccell.2023.
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  31. ZHOU L, Ruscetti M
    Senescent macrophages: A new "old" player in lung cancer development.
    Cancer Cell. 2023 May 20:S1535-6108(23)00175-7. doi: 10.1016/j.ccell.2023.
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  32. ALLEN C, Santagata S
    Meet the authors: Dr. Clint Allen and Dr. Sandro Santagata.
    Cancer Cell. 2023;41:834-836.
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  33. WU Q, Hu G
    A genetic portrait of metastatic seeds in lung adenocarcinoma.
    Cancer Cell. 2023;41:828-830.
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  34. LENGEL HB, Mastrogiacomo B, Connolly JG, Tan KS, et al
    Genomic mapping of metastatic organotropism in lung adenocarcinoma.
    Cancer Cell. 2023;41:970-985.
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  35. GAGLIA G, Burger ML, Ritch CC, Rammos D, et al
    Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma.
    Cancer Cell. 2023;41:871-886.
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    April 2023
  36. WEEDEN CE, Gayevskiy V, Marceaux C, Batey D, et al
    Early immune pressure initiated by tissue-resident memory T cells sculpts tumor evolution in non-small cell lung cancer.
    Cancer Cell. 2023 Apr 13:S1535-6108(23)00092-2. doi: 10.1016/j.ccell.2023.
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  37. MOUSSET A, Lecorgne E, Bourget I, Lopez P, et al
    Neutrophil extracellular traps formed during chemotherapy confer treatment resistance via TGF-beta activation.
    Cancer Cell. 2023;41:757-775.
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  38. PAI JA, Hellmann MD, Sauter JL, Mattar M, et al
    Lineage tracing reveals clonal progenitors and long-term persistence of tumor-specific T cells during immune checkpoint blockade.
    Cancer Cell. 2023;41:776-790.
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    March 2023
  39. KLEMENT JD, Redd PS, Lu C, Merting AD, et al
    Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment.
    Cancer Cell. 2023;41:620-636.
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  40. MANGANA C, Maier BB
    A progressive T cell exhaustion program mapped across tissues in patients with lung cancer on immune checkpoint blockade.
    Cancer Cell. 2023 Mar 10:S1535-6108(23)00048-X. doi: 10.1016/j.ccell.2023.
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    February 2023
  41. NILSSON MB, Yang Y, Heeke S, Patel SA, et al
    CD70 is a therapeutic target upregulated in EMT-associated EGFR tyrosine kinase inhibitor resistance.
    Cancer Cell. 2023;41:340-355.
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    January 2023
  42. PAN Y, Han H, Hu H, Wang H, et al
    KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition.
    Cancer Cell. 2023;41:88-105.
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    December 2022
  43. BALLESTEROS I, Cerezo-Wallis D, Hidalgo A
    Understanding NSCLC, one cell at a time.
    Cancer Cell. 2022;40:1459-1461.
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    October 2022
  44. SALCHER S, Sturm G, Horvath L, Untergasser G, et al
    High-resolution single-cell atlas reveals diversity and plasticity of tissue-resident neutrophils in non-small cell lung cancer.
    Cancer Cell. 2022 Oct 27. pii: S1535-6108(22)00499.
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  45. LAU SCM, Pan Y, Velcheti V, Wong KK, et al
    Squamous cell lung cancer: Current landscape and future therapeutic options.
    Cancer Cell. 2022 Oct 14. pii: S1535-6108(22)00480.
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  46. SKOULIDIS F, Heymach JV, Cascone T
    A STING operation to expose KRAS and STK11 co-mutated lung cancers.
    Cancer Cell. 2022;40:1073-1076.
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  47. MUKHERJEE S, Carrot-Zhang J
    Whole-genome sequencing of East Asian lung cancers reveals new germline pathogenic variants.
    Cancer Cell. 2022;40:1081-1083.
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  48. NASSAR AH, Adib E, Abou Alaiwi S, El Zarif T, et al
    Ancestry-driven recalibration of tumor mutational burden and disparate clinical outcomes in response to immune checkpoint inhibitors.
    Cancer Cell. 2022;40:1161-1172.
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    September 2022
  49. KITAJIMA S, Tani T, Springer BF, Campisi M, et al
    MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer.
    Cancer Cell. 2022 Sep 18. pii: S1535-6108(22)00379.
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  50. LEUNG CSK, Van den Eynde BJ
    Combining personalized neoantigen vaccination with chemotherapy and anti-PD-1 to treat NSCLC.
    Cancer Cell. 2022;40:903-905.
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    August 2022
  51. WANG C, Dai J, Qin N, Fan J, et al
    Analyses of rare predisposing variants of lung cancer in 6,004 whole genomes in Chinese.
    Cancer Cell. 2022 Aug 30. pii: S1535-6108(22)00377.
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  52. AWAD MM, Govindan R, Balogh KN, Spigel DR, et al
    Personalized neoantigen vaccine NEO-PV-01 with chemotherapy and anti-PD-1 as first-line treatment for non-squamous non-small cell lung cancer.
    Cancer Cell. 2022 Aug 17. pii: S1535-6108(22)00359.
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  53. MURPHY BM, Burd CE
    The aging lung microenvironment awakens melanoma metastases.
    Cancer Cell. 2022;40:815-817.
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    July 2022
  54. ELAMIN YY, Robichaux JP, Carter BW, Altan M, et al
    Poziotinib for EGFR exon 20-mutant NSCLC: Clinical efficacy, resistance mechanisms, and impact of insertion location on drug sensitivity.
    Cancer Cell. 2022;40:754-767.
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  55. CARDONA AF, Gonzalez-Cao M, Arrieta O, Rosell R, et al
    Location of EGFR exon 20 insertions matters.
    Cancer Cell. 2022;40:705-708.
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    May 2022
  56. HERBST RS, Wang M, Chen L
    When immunotherapy meets surgery in non-small cell lung cancer.
    Cancer Cell. 2022 May 31. pii: S1535-6108(22)00221.
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  57. HANADA KI, Zhao C, Gil-Hoyos R, Gartner JJ, et al
    A phenotypic signature that identifies neoantigen-reactive T cells in fresh human lung cancers.
    Cancer Cell. 2022;40:479-493.
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    April 2022
  58. MACK PC, Gomez JE, Rodilla AM, Carreno JM, et al
    Longitudinal COVID-19-vaccination-induced antibody responses and Omicron neutralization in patients with lung cancer.
    Cancer Cell. 2022 Apr 20. pii: S1535-6108(22)00174.
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    February 2022
  59. TEILLAUD JL, Dieu-Nosjean MC
    Intratumoral plasma cells: More than a predictive marker of response to anti-PD-L1 treatment in lung cancer?
    Cancer Cell. 2022 Feb 22. pii: S1535-6108(22)00060.
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  60. PATIL NS, Nabet BY, Muller S, Koeppen H, et al
    Intratumoral plasma cells predict outcomes to PD-L1 blockade in non-small cell lung cancer.
    Cancer Cell. 2022 Feb 22. pii: S1535-6108(22)00035.
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    January 2022
  61. COOPER AJ, Sequist LV, Johnson TW, Lin JJ, et al
    LTK fusions: A new target emerges in non-small cell lung cancer.
    Cancer Cell. 2022;40:23-25.
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  62. NEWELL F, Pires da Silva I, Johansson PA, Menzies AM, et al
    Multiomic profiling of checkpoint inhibitor-treated melanoma: Identifying predictors of response and resistance, and markers of biological discordance.
    Cancer Cell. 2022;40:88-102.
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    November 2021
  63. YENERALL P, Kittler R, Minna J
    Structure-based classification of EGFR mutations informs inhibitor selection for lung cancer therapy.
    Cancer Cell. 2021;39:1455-1457.
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  64. LEADER AM, Grout JA, Maier BB, Nabet BY, et al
    Single-cell analysis of human non-small cell lung cancer lesions refines tumor classification and patient stratification.
    Cancer Cell. 2021 Nov 2. pii: S1535-6108(21)00560.
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    October 2021
  65. CHAN JM, Quintanal-Villalonga A, Gao VR, Xie Y, et al
    Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer.
    Cancer Cell. 2021 Oct 12. pii: S1535-6108(21)00497.
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    September 2021
  66. HU H, Piotrowska Z, Hare PJ, Chen H, et al
    Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms.
    Cancer Cell. 2021 Sep 28. pii: S1535-6108(21)00492.
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  67. LE X, Nilsson MB, Robichaux JP, Heymach JV, et al
    ARTEMIS highlights VEGF inhibitors as effective partners for EGFR TKIs in EGFR mutant NSCLC.
    Cancer Cell. 2021;39:1178-1180.
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  68. ZHOU Q, Xu CR, Cheng Y, Liu YP, et al
    Bevacizumab plus erlotinib in Chinese patients with untreated, EGFR-mutated, advanced NSCLC (ARTEMIS-CTONG1509): A multicenter phase 3 study.
    Cancer Cell. 2021;39:1279-1291.
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    August 2021
  69. MOORE AR, Malek S
    The promise and peril of KRAS G12C inhibitors.
    Cancer Cell. 2021;39:1059-1061.
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  70. PE'ER D, Ogawa S, Elhanani O, Keren L, et al
    Tumor heterogeneity.
    Cancer Cell. 2021;39:1015-1017.
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  71. PEARSON JD, Huang K, Pacal M, McCurdy SR, et al
    Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity.
    Cancer Cell. 2021;39:1115-1134.
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  72. GARLANDA C, Mantovani A
    Interleukin-1 in tumor progression, therapy, and prevention.
    Cancer Cell. 2021;39:1023-1027.
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    July 2021
  73. TANAKA K, Yu HA, Yang S, Han S, et al
    Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis.
    Cancer Cell. 2021 Jul 27. pii: S1535-6108(21)00383.
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    May 2021
  74. KLEIN O, Kee D, Markman B, Carlino MS, et al
    Evaluation of TMB as a predictive biomarker in patients with solid cancers treated with anti-PD-1/CTLA-4 combination immunotherapy.
    Cancer Cell. 2021;39:592-593.
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    April 2021
  75. DRAPKIN BJ, Minna JD
    A rational targeted therapy for platinum-resistant small-cell lung cancer.
    Cancer Cell. 2021;39:453-456.
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  76. THOMAS A, Takahashi N, Rajapakse VN, Zhang X, et al
    Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress.
    Cancer Cell. 2021;39:566-579.
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    March 2021
  77. KOS K, de Visser KE
    Neutrophils create a fertile soil for metastasis.
    Cancer Cell. 2021;39:301-303.
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  78. SANCLEMENTE M, Nieto P, Garcia-Alonso S, Fernandez-Garcia F, et al
    RAF1 kinase activity is dispensable for KRAS/p53 mutant lung tumor progression.
    Cancer Cell. 2021;39:294-296.
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  79. GAY CM, Stewart CA, Park EM, Diao L, et al
    Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities.
    Cancer Cell. 2021;39:346-360.
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    February 2021
  80. SRIVASTAVA S, Furlan SN, Jaeger-Ruckstuhl CA, Sarvothama M, et al
    Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade.
    Cancer Cell. 2021;39:193-208.
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    December 2020
  81. XIAO Y, Cong M, Li J, He D, et al
    Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation.
    Cancer Cell. 2020 Dec 31. pii: S1535-6108(20)30660.
    >> Share


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