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Articles published in
J Biol Chem
    March 2024
  1. KANEFSKY J, Basse M, Sokei J, di Martino O, et al
    DISRUPTION OF POLYUNSATURATED FATTY ACID BIOSYNTHESIS DRIVES STING-DEPENDENT ACUTE MYELOID LEUKEMIA CELL MATURATION AND DEATH.
    J Biol Chem. 2024 Mar 22:107214. doi: 10.1016/j.jbc.2024.107214.
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    November 2023
  2. RICHARTZ N, Pietka W, Yadav A, Bostad M, et al
    N-acetyl cysteine turns EPAC activators into potent killers of acute lymphoblastic leukemia cells.
    J Biol Chem. 2023 Nov 30:105509. doi: 10.1016/j.jbc.2023.105509.
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    October 2023
  3. NAMITZ KEW, Showalter SA, Cosgrove MS
    Phase separation promotes a highly active oligomeric scaffold of the MLL1 core complex for regulation of histone H3K4 methylation.
    J Biol Chem. 2023;299:105204.
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    July 2023
  4. WANG P, Wang J, Yao S, Cui M, et al
    Deubiquitinase USP9X stabilizes RNA m(6)A demethylase ALKBH5 and promotes acute myeloid leukemia cell survival.
    J Biol Chem. 2023 Jul 14:105055. doi: 10.1016/j.jbc.2023.105055.
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  5. MILJKOVIC M, Seguin A, Jia X, Cox JE, et al
    Loss of the mitochondrial protein Abcb10 results in altered arginine metabolism in MEL and K562 cells and nutrient stress signaling through ATF4.
    J Biol Chem. 2023;299:104877.
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  6. CASEY NP, Klee CH, Fane A, Caulier B, et al
    Efficient chimeric antigen receptor targeting of a central epitope of CD22.
    J Biol Chem. 2023;299:104883.
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  7. WILLIAMS O, Hu L, Huang W, Patel P, et al
    Nore1 inhibits age-associated myeloid lineage skewing and clonal hematopoiesis but facilitates termination of emergency (stress) granulopoiesis.
    J Biol Chem. 2023;299:104867.
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    June 2023
  8. ZHANG J, Ma C, Yu Y, Liu C, et al
    Single amino acid-based PROTACs trigger degradation of the oncogenic kinase BCR-ABL in chronic myeloid leukemia (CML).
    J Biol Chem. 2023 Jun 29:104994. doi: 10.1016/j.jbc.2023.104994.
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  9. CHEN H, Lu C, Tan Y, Weber-Boyvat M, et al
    Oculocerebrorenal syndrome of Lowe (OCRL) controls leukemic T-cell survival by preventing excessive PI(4,5)P(2) hydrolysis in the plasma membrane.
    J Biol Chem. 2023;299:104812.
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    February 2023
  10. NAMITZ KEW, Tan S, Cosgrove MS
    Hierarchical assembly of the MLL1 core complex regulates H3K4 methylation and is dependent on temperature and component concentration.
    J Biol Chem. 2023;299:102874.
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    January 2023
  11. ZHANG H, Song W, Ma X, Yu M, et al
    Acetylation stabilizes the signaling protein WISP2 by preventing its degradation to suppress the progression of acute myeloid leukemia.
    J Biol Chem. 2023 Jan 31:102971. doi: 10.1016/j.jbc.2023.102971.
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  12. REN R, Horton JR, Chen Q, Yang J, et al
    Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
    J Biol Chem. 2023 Jan 7:102885. doi: 10.1016/j.jbc.2023.102885.
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    December 2022
  13. SHANG Q, Pan C, Zhang X, Yang T, et al
    Nuclear factor Nrf2 promotes glycosidase OGG1 expression by activating the AKT pathway to enhance leukemia cell resistance to cytarabine.
    J Biol Chem. 2022 Dec 14:102798. doi: 10.1016/j.jbc.2022.102798.
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  14. YU S, Ye J, Wang Y, Lu T, et al
    DNA damage to bone marrow stromal cells by anti-leukemia drugs induces chemo-resistance in acute myeloid leukemia via paracrine FGF10-FGFR2 signaling.
    J Biol Chem. 2022 Dec 9:102787. doi: 10.1016/j.jbc.2022.102787.
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    November 2022
  15. JIANG Y, Wang T, Sheng D, Han C, et al
    Aurora A-mediated pyruvate kinase M2 phosphorylation promotes biosynthesis with glycolytic metabolites and tumor cell cycle progression.
    J Biol Chem. 2022;298:102561.
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    August 2022
  16. ZHUANG H, Ren Y, Mao C, Zhong Y, et al
    Induction of zinc finger protein RNF6 auto-ubiquitination for the treatment of myeloma and chronic myeloid leukemia.
    J Biol Chem. 2022 Aug 1:102314. doi: 10.1016/j.jbc.2022.102314.
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  17. ORUGANTI B, Lindahl E, Yang J, Amiri W, et al
    Allosteric enhancement of the BCR-Abl1 kinase inhibition activity of nilotinib by cobinding of asciminib.
    J Biol Chem. 2022;298:102238.
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    April 2022
  18. YUAN Y, Li K, Teng F, Wang W, et al
    Leukemia inhibitory factor protects against liver steatosis in non-alcoholic fatty liver disease patients and obese mice.
    J Biol Chem. 2022 Apr 18:101946. doi: 10.1016/j.jbc.2022.101946.
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  19. DELGADO M, Rainwater RR, Heflin B, Urbaniak A, et al
    Primary acute lymphoblastic leukemia cells are susceptible to microtubule depolymerization in G1 and M phases through distinct cell death pathways.
    J Biol Chem. 2022 Apr 15:101939. doi: 10.1016/j.jbc.2022.101939.
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    February 2022
  20. LEE H, Sun R, Niehrs C
    Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RW(d).
    J Biol Chem. 2022;298:101586.
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    December 2021
  21. RAVEENDRA-PANICKAR D, Finlay D, Layng FI, Lambert LJ, et al
    Discovery of novel furanylbenzamide inhibitors that target oncogenic tyrosine phosphatase SHP2 in leukemia cells.
    J Biol Chem. 2021 Dec 9:101477. doi: 10.1016/j.jbc.2021.101477.
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    October 2021
  22. BOWEN NE, Temple J, Shepard C, Oo A, et al
    Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins.
    J Biol Chem. 2021;297:101170.
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  23. SHEN H, Gonskikh Y, Stoute J, Liu KF, et al
    Human DIMT1 generates N2(6,6)A-dimethylation-containing small RNAs.
    J Biol Chem. 2021;297:101146.
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    August 2021
  24. RONDELLI CM, Perfetto M, Danoff A, Bergonia H, et al
    The ubiquitous mitochondrial protein unfoldase CLPX regulates erythroid heme synthesis by control of iron utilization and heme synthesis enzyme activation and turnover.
    J Biol Chem. 2021;297:100972.
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    January 2021
  25. POPOV AV, Endutkin AV, Yatsenko DD, Yudkina AV, et al
    Molecular dynamics approach to identification of new OGG1 cancer-associated somatic variants with impaired activity.
    J Biol Chem. 2021;296:100229.
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  26. LOPUSNA K, Nowialis P, Opavska J, Abraham A, et al
    Decreases in different Dnmt3b activities drive distinct development of hematologic malignancies in mice.
    J Biol Chem. 2021;296:100285.
    >> Share

  27. SANDOVAL JE, Reich NO
    p53 and TDG are dominant in regulating the activity of the human de novo DNA methyltransferase DNMT3A on nucleosomes.
    J Biol Chem. 2021;296:100058.
    >> Share


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