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Articles published in
PLoS Pathog
    January 2026
  1. PEREZ-BETANCOURT Y, Shi M, Missiakas D
    Examining the role of IgA in a persistent model of Staphylococcus aureus colonization.
    PLoS Pathog. 2026;22:e1013924.
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  2. CHEN B, Vanden Buijs L, Vanderheijden N, Desmarets L, et al
    Serine protease-driven entry and S2' cleavage flexibility of feline coronavirus during feline enterocyte infections.
    PLoS Pathog. 2026;22:e1013854.
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  3. BISTA S, Brangulis K, Bhattachan B, Foor SD, et al
    Targeting of interaction between BB0323-BB0238 informs new paradigms in Lyme disease therapeutics.
    PLoS Pathog. 2026;22:e1013805.
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  4. MOLOTO K, Newton-Foot M, Dramowski A, Ayala-Montano S, et al
    Carbapenem resistant Klebsiella pneumoniae isolates at a tertiary hospital in Cape Town, South Africa, are dominated by specific local clones rather than previously described international lineages.
    PLoS Pathog. 2026;22:e1013859.
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  5. GUPTA S, Matsunaga J, Ratitong B, Manion A, et al
    cGAS-STING dependent type I IFN reduces Leptospira interrogans renal colonization in mice.
    PLoS Pathog. 2026;22:e1013250.
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  6. GUAN J, Wang Y, Fu M, Tang L, et al
    EnP1 exploits H2Aub-dependent epigenetic reprogramming to promote microsporidia proliferation in host cells.
    PLoS Pathog. 2026;22:e1013853.
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  7. PERSHING NL, Brzozowski RS, Schmidt AK, Faith DR, et al
    A prophage-encoded sRNA limits phage infection of adherent-invasive E. coli.
    PLoS Pathog. 2026;22:e1013836.
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  8. AHMAD SS, Ebohon O, McClune ME, Trimble RN, et al
    Peptidoglycan architecture dictates protein interactions, tissue tropism, and arthritis in the Lyme disease spirochete Borrelia burgdorferi.
    PLoS Pathog. 2026;22:e1013849.
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  9. TAHIRI G, Lax C, Binder U, Scheler J, et al
    A BRCT domain-containing protein induced in early phagocytosis plays a crucial role in the pathogenesis of the mucoralean Rhizopus microsporus.
    PLoS Pathog. 2026;22:e1013653.
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  10. MARTINEZ E, Im H, Mohasin M, Wilson L, et al
    The Oxylipin Dependent Quorum Sensing System enhances Pseudomonas aeruginosa dissemination during burn-associated infection.
    PLoS Pathog. 2026;22:e1013885.
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    December 2025
  11. XU Y, Zhang K, Li S, Qiao L, et al
    Mycobacterium tuberculosis manipulates LINC02528 in macrophages to modulate anti-tuberculosis metabolic immunity.
    PLoS Pathog. 2025;21:e1013810.
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  12. MOTTA C, Turley M, Barbieri G, Fama A, et al
    A single amino acid substitution in Fibronectin Binding protein A (FnBPA) governs Staphylococcus aureus virulence via host transglutaminase-mediated fibrin crosslinking.
    PLoS Pathog. 2025;21:e1013743.
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  13. ENZ U, Gul E, Maurer L, Cerepenkaite K, et al
    TTSS-2 virulence drives inflammatory destruction of the gut epithelial barrier and modulates inflammatory response profiles in the Salmonella-infected mouse gut.
    PLoS Pathog. 2025;21:e1013733.
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  14. SILVA M, Pinto AJ, Beites T
    Essential redundancies fuel Mycobacterium tuberculosis adaptation to the host.
    PLoS Pathog. 2025;21:e1013749.
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  15. MEHRA A, Garrett EM, Serody CJ, Tamayo R, et al
    Phase variation of Clostridioides difficile colony morphology occurs via modulation of cell division.
    PLoS Pathog. 2025;21:e1013471.
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  16. BOTHRA A, Pomerantsev A, Schwarz B, Mondal A, et al
    Environmental regulation of toxin production in Bacillus anthracis.
    PLoS Pathog. 2025;21:e1013587.
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  17. POSPISILOVA M, Dreus A, Matheova P, Schmidtova J, et al
    Bimodal expression of Type 3 Secretion System 2 enables cooperative virulence among intracellular Salmonella Typhimurium.
    PLoS Pathog. 2025;21:e1013728.
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  18. MULLER NF, Wick RR, Judd LM, Williamson DA, et al
    Quantifying plasmid movement in drug-resistant Shigella species using phylodynamic inference.
    PLoS Pathog. 2025;21:e1013621.
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  19. BECKMAN I V RL, Martinez B, Santiago FZ, Echeverria GN, et al
    Molecular response to the non-lytic peptide bac7 (1-35) triggers disruption of Klebsiella pneumoniae biofilm.
    PLoS Pathog. 2025;21:e1013437.
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  20. DRAGOTAKES Q, Jacobs E, Gerbig G, Greengo S, et al
    A conserved enzymatic toolkit targeting host cell metabolism is associated with Cryptococcus neoformans intracellular survival in protozoal and mammalian phagocytic cells.
    PLoS Pathog. 2025;21:e1013787.
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  21. TU J, Yang J, Song K, Wang J, et al
    Colanic acid-mediated phage resistance enhances virulence in high-risk global clone Escherichia coli ST410.
    PLoS Pathog. 2025;21:e1013807.
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  22. SMALLMAN TR, Wang X, Kostoulias X, Wright A, et al
    Comparative analysis of shared and unique mechanisms important for diverse strains of Pasteurella multocida to cause systemic infection in mice.
    PLoS Pathog. 2025;21:e1013398.
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  23. PERRIER A, Budin-Verneuil A, Hallez R
    Functional interplay between (p)ppGpp and RNAP in Acinetobacter baumannii.
    PLoS Pathog. 2025;21:e1013795.
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  24. MELO G, Barbosa CHD, Magrini E, Garlanda C, et al
    Activation of B1 B cells by F. tularensis atypical LPS depends on classical complement and C3a.
    PLoS Pathog. 2025;21:e1013799.
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  25. FAN L, Sun Y, Lou F, Fang Z, et al
    Pp6-Pfkfb1 axis modulates intracellular bacterial proliferation by orchestrating host-pathogen metabolic crosstalk.
    PLoS Pathog. 2025;21:e1013304.
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  26. GWYNNE PJ, Bourgeois JS, Pandit A, Asara JM, et al
    Lipid scavenging by the Lyme disease spirochete Borrelia burgdorferi.
    PLoS Pathog. 2025;21:e1013821.
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  27. GLASER K, Rieger CB, Paluszkiewicz E, Thome UH, et al
    Ureaplasma-driven inhibition of the epithelial Na+ transport in fetal alveolar cells: A novel mechanism of Ureaplasma-mediated preterm lung disease.
    PLoS Pathog. 2025;21:e1013837.
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  28. WARD D, Little RH, Thompson CMA, Malone JG, et al
    Cyclic-di-GMP controls Type III effector export and symptom development in Pseudomonas syringae infections via the export ATPase HrcN.
    PLoS Pathog. 2025;21:e1013376.
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    November 2025
  29. HORNER EM, Lachmayer V, Hermanns T, Moldovan A, et al
    Identification and characterization of a ubiquitin E3 RING ligase of the Chlamydia-like bacterium Simkania negevensis.
    PLoS Pathog. 2025;21:e1013626.
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  30. MIKI T, Yamaguchi H, Kobayashi M, Ito M, et al
    RegIIIbeta promotes Salmonella Typhimurium colonization of the gut in the early-stage gastrointestinal infection by enhancing flagella-driven locomotion.
    PLoS Pathog. 2025;21:e1013665.
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  31. NEILL DR, Clarke TB
    The metabolic, microbial and immunological demands of pneumococcal colonisation.
    PLoS Pathog. 2025;21:e1013675.
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  32. PERITORE-GALVE FC, Kroh HK, Shupe JA, Ehni AG, et al
    The monoclonal antibody AZD5148 confers broad protection against TcdB-diverse Clostridioides difficile strains in mice.
    PLoS Pathog. 2025;21:e1013651.
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  33. WANG D, Chen Z, Xu C, Jiao X, et al
    Functional synergy of heteropentameric B subunits underlies virulence in a Salmonella A2B5 toxin.
    PLoS Pathog. 2025;21:e1013684.
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  34. MUIR YSS, Wright BR, Casteriano A, Crowther MS, et al
    The relationships of viral and protozoal co-infections to Chlamydia pecorum infection and chlamydiosis outcomes in northern koalas (Phascolarctos cinereus).
    PLoS Pathog. 2025;21:e1013632.
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  35. ROYER ALM, Dion E, Umansky AA, Avino M, et al
    Structural determinants of SlpA-mediated phage recognition in Clostridioides difficile.
    PLoS Pathog. 2025;21:e1013724.
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  36. FRISCH T, Geiser P, Komi M, Karlsson PA, et al
    The pcnB gene sustains Shigella flexneri virulence.
    PLoS Pathog. 2025;21:e1013727.
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    October 2025
  37. CHIN J, Abeydeera N, Repasy T, Rivera-Lugo R, et al
    Mycobacterium tuberculosis triggers reduced inflammatory cytokine responses and virulence in mice lacking Tax1bp1.
    PLoS Pathog. 2025;21:e1012829.
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  38. BROKAW A, Wallen G, Orvis A, Kwon HJ, et al
    The serine protease HtrA regulates Group B Streptococcus virulence and affects the host response to infection.
    PLoS Pathog. 2025;21:e1013562.
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  39. LIU Y, Yang Z, Xiang Y, Cheng G, et al
    Single-cell analysis reveals an important role of CD137L+ macrophages in the host response to uropathogenic Escherichia coli infection in the bladder.
    PLoS Pathog. 2025;21:e1013543.
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  40. LANGE T, Sprague JL, Vij R, Alonso-Roman R, et al
    "Pour some sugar on me"-Environmental Candida albicans isolates and the evolution of increased pathogenicity and antifungal resistance through sugar adaptation.
    PLoS Pathog. 2025;21:e1013542.
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  41. ROE SK, Mazgaj R, Zhu T, Esmaeeli M, et al
    The gonococcal vaccine candidate antigen NGO1701 is a N. gonorrhoeae periplasmic copper storage protein.
    PLoS Pathog. 2025;21:e1013559.
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  42. YABAJI SM, Lata S, Tseng AE, Araveti PB, et al
    Dysplastic lung repair fosters a tuberculosis-promoting microenvironment through maladaptive macrophage polarization.
    PLoS Pathog. 2025;21:e1013563.
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  43. ARIF SJ, Hoffman KM, Flynn JM, Wiggen TD, et al
    Host- and microbial-mediated mucin degradation differentially shape Pseudomonas aeruginosa physiology and gene expression.
    PLoS Pathog. 2025;21:e1013568.
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  44. XIE Y, Ke W, Wong KH, Wang L, et al
    Persister cells in human fungal pathogens.
    PLoS Pathog. 2025;21:e1013483.
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  45. THOMPSON RN, Blumenthal A, Morrison M, Thomson RM, et al
    The microbiome and gut-lung axis in nontuberculous mycobacterial pulmonary disease.
    PLoS Pathog. 2025;21:e1013603.
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  46. FENG J, Gao L, Qiu L, Chao W, et al
    Dietary tannic acid promotes intestinal clearance of C. albicans by cross-linking hyphal chitosan.
    PLoS Pathog. 2025;21:e1013596.
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  47. HU LI, Ozer EA, Seifert HS
    Flavin affinity for the reductase HpaC differentially sensitizes Neisseria gonorrhoeae during Type IV pilus-dependent killing.
    PLoS Pathog. 2025;21:e1013607.
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  48. GOERING ER, Clatworthy AE, Parada-Kusz M, Bagnall J, et al
    Kmo restricts Salmonella in a whole organism infection model by promoting macrophage lysosomal acidification through kainate receptor antagonism.
    PLoS Pathog. 2025;21:e1013273.
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  49. VAN HOORDE S, Vereecke N, Sperling D, He X, et al
    External factors influence intrinsic differences in Stx2e production by Porcine Shiga Toxin-producing Escherichia coli strains.
    PLoS Pathog. 2025;21:e1013616.
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  50. SHEM-TOV R, Gal-Mor O
    HilE mediates motility thermoregulation in typhoidal Salmonella serovars at elevated physiological temperatures.
    PLoS Pathog. 2025;21:e1013133.
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    September 2025
  51. APTE S, Bonifacio-Pereira GK, Ghosh S, Mandal SK, et al
    Commensal to pathogen switch in Streptococcus pneumoniae is influenced by a thermosensing master regulator.
    PLoS Pathog. 2025;21:e1013545.
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  52. KHAN I, MacDonald SJ, Markusson S, Kies PJ, et al
    Defined roles for the Staphylococcus aureus POT transporter DtpT in di/tripeptide uptake and glutathione utilisation inside human macrophages.
    PLoS Pathog. 2025;21:e1013535.
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  53. MARRO FC, Brocard J, Faure A, Sion A, et al
    Monitoring intracellular replication dynamics unveils high proportion of non-replicating antibiotic-tolerant Staphylococcus aureus inside osteoblasts.
    PLoS Pathog. 2025;21:e1013525.
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  54. CHOSHI P, Pedretti S, Chimbetete T, Gangula R, et al
    The association of class II HLA alleles with tuberculosis-associated immune reconstitution inflammatory syndrome.
    PLoS Pathog. 2025;21:e1013497.
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  55. RIVAULT A, Bernut A, Ben-Neji M, Abrantes M, et al
    HIV-1 Tat favors the multiplication of Mycobacterium tuberculosis and Toxoplasma by inhibiting clathrin-mediated endocytosis and autophagy.
    PLoS Pathog. 2025;21:e1013183.
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  56. SAIGA H, Ueno M, Tamura T, Tsujimura Y, et al
    Mycobacterium tuberculosis impairs protective cytokine production via transcription factor MafB manipulation.
    PLoS Pathog. 2025;21:e1013476.
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  57. MUKHERJEE D, Noor S, Mukherjee T, Singh M, et al
    Intracellular formate modulates a motility-invasion switch in Salmonella Typhimurium.
    PLoS Pathog. 2025;21:e1013453.
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  58. HUO D, Yang R, Fu J, Chen J, et al
    CK2 derived from brain microvascular endothelial cells induces astrocyte inflammatory response in Escherichia coli-induced meningitis.
    PLoS Pathog. 2025;21:e1013464.
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  59. HERNANDEZ KA, Porsch EA, Munoz VL, St Geme Iii JW, et al
    Identification of a Kingella kingae factor H binding protein that is the major determinant of serum resistance.
    PLoS Pathog. 2025;21:e1013473.
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  60. NGUYEN TNT, Howells G, Short FL
    How Klebsiella pneumoniae controls its virulence.
    PLoS Pathog. 2025;21:e1013499.
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  61. WANG R, Lv J, Chen L, Zhao Y, et al
    Antifungal persistence: Clinical relevance and mechanisms.
    PLoS Pathog. 2025;21:e1013456.
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  62. MASSICOTTE MA, Fiebig AA, Bogza A, Coombes BK, et al
    The Salmonella phage shock protein system is required for defense against host antimicrobial peptides.
    PLoS Pathog. 2025;21:e1013132.
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  63. SIVAKUMAR N, Fuentes E, Selvik LK, Arch M, et al
    Genome-wide phenotypic insights into mycobacterial virulence using Drosophila melanogaster.
    PLoS Pathog. 2025;21:e1013474.
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  64. WIEHLMANN L, Adams T, Urbanke C, Horatzek S, et al
    Versatile roles of rubredoxin reductase of Pseudomonas aeruginosa TBCF10839 in virulence and stress protection.
    PLoS Pathog. 2025;21:e1013465.
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  65. LIU S, He C, Zhang Y, Liu S, et al
    Regulation of host immunity by a novel Legionella pneumophila E3 ubiquitin ligase.
    PLoS Pathog. 2025;21:e1013522.
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  66. WALDMANN AK, Ammendolia DA, Sydor AM, Li R, et al
    Proximity labelling reveals VPS13C as a regulator of Salmonella-containing vacuole fission.
    PLoS Pathog. 2025;21:e1013507.
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  67. LI S, Ma Z, Lin H, Pan F, et al
    STK-mediated FadR phosphorylation regulates the acid resistance and virulence of Streptococcus suis.
    PLoS Pathog. 2025;21:e1013534.
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  68. AKYAW PA, Paulo TF, Lafuente E, Sucena E, et al
    Pathogen-induced damage in Drosophila: Uncoupling disease tolerance from resistance.
    PLoS Pathog. 2025;21:e1013482.
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  69. AUDI A, Zeineddine S, Jaber S, Osta MA, et al
    A PGRPLC1/Rel2-F axis controls Anopheles gambiae resistance to systemic infections with Gram-positive bacteria containing Lys-type peptidoglycan.
    PLoS Pathog. 2025;21:e1013527.
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  70. SUN YF, Guo SY, Wang SQ, Li RT, et al
    Chimeric PRR T-cell-engager targeting cell surface beta-1,3-glucan for invasive candidiasis.
    PLoS Pathog. 2025;21:e1013508.
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  71. TAKEUCHI T, Gotoh Y, Hayashi T, Kawabata H, et al
    Antigenic variation is caused by long plasmid segment conversion in a hard tick-borne relapsing fever Borrelia miyamotoi.
    PLoS Pathog. 2025;21:e1013514.
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  72. MCCALLA AJ, Walker FC, Bisaro F, Rodriguez-Anavitate M, et al
    Acinetobacter phages use distinct strategies to breach the capsule barrier.
    PLoS Pathog. 2025;21:e1013536.
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  73. KERWIEN A, Korner B, Meyer I, Teschke Y, et al
    T6SS4 is heterogeneously expressed in Yersinia pseudotuberculosis and is a target for transcriptional and post-transcriptional regulation.
    PLoS Pathog. 2025;21:e1013356.
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  74. BUDA DE CESARE G, Cruz MR, Cristy SA, Vega LA, et al
    The antifungal mechanism of EntV-derived peptides is associated with a reduction in extracellular vesicle release.
    PLoS Pathog. 2025;21:e1013519.
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    August 2025
  75. ZEEB M, Kusejko K, Hartnack S, Pasin C, et al
    Infection with Mycobacterium tuberculosis alters the antibody response to HIV-1.
    PLoS Pathog. 2025;21:e1013350.
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  76. NIEWOLD P, IJsselsteijn ME, Dijkman K, de Miranda N, et al
    NK cell-macrophage interactions in granulomas correlate with limited tuberculosis pathology.
    PLoS Pathog. 2025;21:e1012980.
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  77. MOLDOVAN A, Flannagan RS, Ruhling M, Stelzner K, et al
    Inactivation of branched-chain amino acid uptake halts Staphylococcus aureus growth and induces bacterial quiescence within macrophages.
    PLoS Pathog. 2025;21:e1013291.
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  78. LI XY, He P, Wang S, Wang Y, et al
    Streptococcus pneumoniae synchronizes the states of cell wall peptidoglycan acetylation and genome methylation by programmed DNA inversions.
    PLoS Pathog. 2025;21:e1013286.
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  79. KARAMOOZ E, Kim SJ, Peterson JC, Tammen AE, et al
    Two-pore channels in MR1-dependent presentation of Mycobacterium tuberculosis infection.
    PLoS Pathog. 2025;21:e1013342.
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  80. ERMOLI F, Malengo G, Spahn C, Brianceau C, et al
    Yersinia actively downregulates type III secretion and adhesion at higher cell densities.
    PLoS Pathog. 2025;21:e1013423.
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    July 2025
  81. CHA H, Won D, Kang S, Kim ES, et al
    The calcineurin pathway regulates extreme thermotolerance, cell membrane and wall integrity, antifungal resistance, and virulence in Candida auris.
    PLoS Pathog. 2025;21:e1013363.
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  82. GUO Y, Stulz SV, Kessie DK, Vollmuth N, et al
    Secreted ISG15 induced by Chlamydia trachomatis infection exerts immunomodulatory effects on IFN-gamma defense and inflammation.
    PLoS Pathog. 2025;21:e1013315.
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  83. LI Y, Xie Q, Yang L, Jiang Q, et al
    RNF213 regulates blood?brain barrier integrity by targeting TRAF3 for type I interferon activation during A. baumannii infection.
    PLoS Pathog. 2025;21:e1013333.
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  84. GREENE J, Cotten KL, Snyder RA, Huiszoon RC, et al
    Yersinia pseudotuberculosis growth arrest during type-III secretion system expression is associated with altered ribosomal protein expression and decreased gentamicin susceptibility.
    PLoS Pathog. 2025;21:e1012548.
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  85. BERKACHY R, Mishra V, Biswas P, Frankel G, et al
    Citrobacter rodentium infection activates colonic lamina propria group 2 innate lymphoid cells.
    PLoS Pathog. 2025;21:e1013276.
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  86. WANG Y, Liu R, Lv W, Xia K, et al
    The conserved transcription factor PrlP modulates colonization and pathogenicity of Streptococcus suis in response to environmental stress.
    PLoS Pathog. 2025;21:e1013314.
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  87. MUSTAREE S, Podicheti R, Rusch D, Rowe-Magnus DA, et al
    Spatio-genetically coordinated TPR domain-containing proteins modulate c-di-GMP signaling in Vibrio vulnificus.
    PLoS Pathog. 2025;21:e1013353.
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  88. MCCAUSLAND JW, Kloos ZA, Irnov I, Sonnert ND, et al
    Bacterial and host enzymes modulate the pro-inflammatory response elicited by the peptidoglycan of Lyme disease agent Borrelia burgdorferi.
    PLoS Pathog. 2025;21:e1013324.
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  89. POWELL-PIERCE AD, Booth CE Jr, Smith PG, Shapiro BL, et al
    BBK32 attenuates antibody-dependent complement-mediated killing of infectious Borreliella burgdorferi isolates.
    PLoS Pathog. 2025;21:e1013361.
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  90. MULLARD RM, Sheedlo MJ
    Oligomerization of the Clostridioides difficile transferase B component proceeds through a stepwise mechanism.
    PLoS Pathog. 2025;21:e1013186.
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  91. LIU Y, Zhou W, Zhao J, Shi Q, et al
    VapC toxins promote the pathogenesis of Rickettsia heilongjiangensis by cleaving essential RNAs from both Rickettsia and its host.
    PLoS Pathog. 2025;21:e1013380.
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    June 2025
  92. SMITH RE, Michno BJ, Christena RL, O'Dea F, et al
    Enterococcal cell wall remodelling underpins pathogenesis via the release of the Enteroccocal Polysaccharide Antigen (EPA).
    PLoS Pathog. 2025;21:e1012771.
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  93. LIU D, Mai D, Jahn AN, Murray TA, et al
    APOE protects against severe infection with Mycobacterium tuberculosis by restraining production of neutrophil extracellular traps.
    PLoS Pathog. 2025;21:e1013267.
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  94. BECKER SH, Ronayne CE, Bold TD, Jenkins MK, et al
    Antigen-specific CD4+ T cells promote monocyte recruitment and differentiation into glycolytic lung macrophages to control Mycobacterium tuberculosis.
    PLoS Pathog. 2025;21:e1013208.
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  95. LAWRENCE LA, Williams ME, Vidal P, Varughese RS, et al
    Murine modeling of menstruation identifies immune correlates of protection during Chlamydia muridarum challenge.
    PLoS Pathog. 2025;21:e1012276.
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  96. ZHOU J, Yang Q, Xu H, Chen H, et al
    TIGIT blockade improves anti-Mycobacterium tuberculosis immunity.
    PLoS Pathog. 2025;21:e1013228.
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  97. GAO R, Wang H, Cui Z, Du Y, et al
    EPHA5 regulates antifungal innate immunity by phosphorylating EPHB2 and Dectin-1.
    PLoS Pathog. 2025;21:e1013179.
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  98. SCHUBERT C, Naf J, Petukhov L, Laganenka L, et al
    Strain-specific galactose utilization by commensal E. coli mitigates Salmonella establishment in the gut.
    PLoS Pathog. 2025;21:e1013232.
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  99. MISHRA S, Helminiak L, Kim HK
    Polysaccharide synthesis operon modulates Rickettsia-endothelial cell interactions.
    PLoS Pathog. 2025;21:e1013277.
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  100. LIN J, Filler SG
    Host targets of candidalysin.
    PLoS Pathog. 2025;21:e1013284.
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  101. WANG J, Hu H, Wang Q, Zhu T, et al
    A novel genus of virulent phage targeting Acinetobacter baumannii: Efficacy and safety in a murine model of pulmonary infection.
    PLoS Pathog. 2025;21:e1013268.
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  102. CRITCHLOW JM, Rocchio JS, McKell MC, Campbell CJ, et al
    The zinc metalloprotein MigC impacts cell wall biogenesis through interactions with an essential Mur ligase in Acinetobacter baumannii.
    PLoS Pathog. 2025;21:e1013209.
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  103. CHAICHANA P, Satapoomin N, Kullapanich C, Chuenklin S, et al
    Comparative virulence analysis of seven diverse strains of Orientia tsutsugamushi reveals a multifaceted and complex interplay of virulence factors responsible for disease.
    PLoS Pathog. 2025;21:e1012833.
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    May 2025
  104. WU Y, Zou Y, Dai Y, Lu H, et al
    Adaptive morphological changes link to poor clinical outcomes by conferring echinocandin tolerance in Candida tropicalis.
    PLoS Pathog. 2025;21:e1013220.
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  105. CHEN Y, Hagopian B, Tan S
    Cholesterol metabolism and intrabacterial potassium homeostasis are intrinsically related in Mycobacterium tuberculosis.
    PLoS Pathog. 2025;21:e1013207.
    >> Share

  106. SOBEN M, Guerrero P, Guiu A, Yanez A, et al
    Candida albicans-stimulated hematopoietic stem and progenitor cells generate trained neutrophils with enhanced mitochondrial ROS production that defend against infection.
    PLoS Pathog. 2025;21:e1013170.
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  107. LA BELLA AA, Santiago-Tirado FH, Flores-Mireles AL
    Candida auris is emerging as a prevalent urinary pathogen.
    PLoS Pathog. 2025;21:e1013138.
    >> Share

  108. TANG H, Wang Z, Li C, Yu J, et al
    Disruption of sulfur transferase complex increases bacterial intramacrophage persistence.
    PLoS Pathog. 2025;21:e1013136.
    >> Share

  109. NGUYEN QH, Lai CHR, Norris MJ, Ng D, et al
    A surface lipoprotein on Pasteurella multocida binds complement factor I to promote immune evasion.
    PLoS Pathog. 2025;21:e1012686.
    >> Share

  110. ELSENER TA, Cehovin A, Philp C, Fortney K, et al
    Origin, evolution, and success of pbla, the gonococcal beta-lactamase plasmid, and implications for public health.
    PLoS Pathog. 2025;21:e1013151.
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  111. LAGANENKA L, Schubert C, Sichert A, Kalita I, et al
    Interplay between chemotaxis, quorum sensing, and metabolism regulates Escherichia coli-Salmonella Typhimurium interactions in vivo.
    PLoS Pathog. 2025;21:e1013156.
    >> Share

  112. GUERRA FE, Karlinsey JE, Libby SJ, Fang FC, et al
    Evasion of serum antibodies and complement by Salmonella Typhi and Paratyphi A.
    PLoS Pathog. 2025;21:e1012917.
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  113. LUO Q, Shen L, Yang S, Zhang Y, et al
    Caspase-1-licensed pyroptosis drives dsRNA-mediated necroptosis and dampens host defense against bacterial pneumonia.
    PLoS Pathog. 2025;21:e1013167.
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  114. ZHANG H, Wang S, Zhang Y, Hua W, et al
    Mutations in the transcriptional regulator MAB_2885 confer tedizolid and linezolid resistance through the MmpS-MmpL efflux pump MAB_2302-MAB_2303 in Mycobacterium abscessus.
    PLoS Pathog. 2025;21:e1013190.
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  115. RIBIS JW, Nieto C, DiBenedetto NV, Mehra A, et al
    Unique growth and morphology properties of Clade 5 Clostridioides difficile strains revealed by single-cell time-lapse microscopy.
    PLoS Pathog. 2025;21:e1013155.
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  116. KWAKU GN, Jensen KN, Simaku P, Floyd DJ, et al
    Extracellular vesicles from diverse fungal pathogens induce species-specific and endocytosis-dependent immunomodulation.
    PLoS Pathog. 2025;21:e1012879.
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  117. ROLLAND SJ, Lifschin ZJ, Weddle EA, Yum LK, et al
    Host PIK3C3 promotes Shigella flexneri spread from cell to cell through vacuole formation.
    PLoS Pathog. 2025;21:e1012707.
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    April 2025
  118. DAS D, Ganesh SM, Mishra A, Netea MG, et al
    The Emerging Fungal Pathogen Candida auris Induces IFNgamma to Colonize the Skin.
    PLoS Pathog. 2025;21:e1013114.
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  119. ZHANG H, Jin Q, Li J, Wang J, et al
    Astrocyte-derived complement C3 facilitated microglial phagocytosis of synapses in Staphylococcus aureus-associated neurocognitive deficits.
    PLoS Pathog. 2025;21:e1013126.
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  120. MARLI MT, Nordraak AOO, de Bakker V, Winther AR, et al
    Genome-wide analysis of fitness determinants of Staphylococcus aureus during growth in milk.
    PLoS Pathog. 2025;21:e1013080.
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  121. QU J, Yin L, Qin S, Sun X, et al
    Identification of the Pseudomonas aeruginosa AgtR-CspC-RsaL pathway that controls Las quorum sensing in response to metabolic perturbation and Staphylococcus aureus.
    PLoS Pathog. 2025;21:e1013054.
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  122. LE BRIS J, Chen N, Supandy A, Rendueles O, et al
    Phage therapy for Klebsiella pneumoniae: Understanding bacteria-phage interactions for therapeutic innovations.
    PLoS Pathog. 2025;21:e1012971.
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  123. REUVEN AD, Katzenell S, Mwaura BW, Bliska JB, et al
    ExoS effector in Pseudomonas aeruginosa Hyperactive Type III secretion system mutant promotes enhanced Plasma Membrane Rupture in Neutrophils.
    PLoS Pathog. 2025;21:e1013021.
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  124. LIU J, Cao Q, Ewing M, Zuo Z, et al
    ATP depletion in anthrax edema toxin pathogenesis.
    PLoS Pathog. 2025;21:e1013017.
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  125. GANDHI S, Puravankara S, Mondal AK, Chauhan A, et al
    Vibrio cholerae cytolysin induces pro-inflammatory and death signals through novel TLR assembly.
    PLoS Pathog. 2025;21:e1013033.
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  126. WATANABE T, Nagai M, Ishibashi Y, Iwasaki M, et al
    Vacuolar sterol beta-glucosidase EGCrP2/Sgl1 deficiency in Cryptococcus neoformans: Dysfunctional autophagy and Mincle-dependent immune activation as targets of novel antifungal strategies.
    PLoS Pathog. 2025;21:e1013089.
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  127. THORSTENSON JC, Horswill AR
    Staphylococcus aureus SspA (V8 protease): New skin pathogenesis insights into an old enzyme.
    PLoS Pathog. 2025;21:e1013048.
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  128. AMELINE C, Seixas E, Barreto HC, Frazao N, et al
    Evolution of Escherichia coli strains under competent or compromised adaptive immunity.
    PLoS Pathog. 2025;21:e1012442.
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  129. ALSETH EO, Roush C, Irby I, Kopylov M, et al
    Mystique, a broad host range Acinetobacter phage, reveals the impact of culturing conditions on phage isolation and infectivity.
    PLoS Pathog. 2025;21:e1012986.
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  130. MCGOWEN K, Funck T, Wang X, Zinga S, et al
    Efflux pumps and membrane permeability contribute to intrinsic antibiotic resistance in Mycobacterium abscessus.
    PLoS Pathog. 2025;21:e1013027.
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  131. CHOI E, Ryu E, Kim D, Byun JW, et al
    The dual functions of the GTPase BipA in ribosome assembly and surface structure biogenesis in Salmonella enterica serovar Typhimurium.
    PLoS Pathog. 2025;21:e1013047.
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  132. CHEN W, Su X, Pan Y, Zhou H, et al
    Chlamydial protease-like activity factor targets SLC7A11 for degradation to induce ferroptosis and facilitate progeny releases.
    PLoS Pathog. 2025;21:e1013060.
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  133. SOLGER F, Rauch J, Vormittag S, Fan M, et al
    Inter-kingdom signaling by the Legionella autoinducer LAI-1 involves the antimicrobial guanylate binding protein GBP.
    PLoS Pathog. 2025;21:e1013026.
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  134. LI Y, Meagher RB, Lin X
    Tailoring mRNA lipid nanoparticles for antifungal vaccines.
    PLoS Pathog. 2025;21:e1013091.
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  135. FREEMAN MJ, Eral NJ, Sauer JD
    Listeria monocytogenes requires phosphotransferase systems to facilitate intracellular growth and virulence.
    PLoS Pathog. 2025;21:e1012492.
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    March 2025
  136. SCHWARDT NH, Halsey CR, Sanchez ME, Ngo BM, et al
    A genome-wide screen in ex vivo gallbladders identifies Listeria monocytogenes factors required for virulence in vivo.
    PLoS Pathog. 2025;21:e1012491.
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  137. TIAN Y, Wen Y, Wang X, Zhang Y, et al
    The efflux pump SugE2 involved in protection of Salmonella 4,[5],12:i:- against quaternary ammonium salts and inhibition of virulence.
    PLoS Pathog. 2025;21:e1012951.
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  138. ZHAO Y, Zhou Z, Cai G, Zhang D, et al
    Systemic infection by Candida albicans requires FASN-alpha subunit induced cell wall remodeling to perturb immune response.
    PLoS Pathog. 2025;21:e1012865.
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  139. GOLI SH, Lim JY, Basaran-Akgul N, Templeton SP, et al
    Adiponectin pathway activation dampens inflammation and enhances alveolar macrophage fungal killing via LC3-associated phagocytosis.
    PLoS Pathog. 2025;21:e1012363.
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  140. CHEN K, Shen S, Lv Z, Guo M, et al
    Lytic coelomocyte death is tuned by cleavage but not phosphorylation of MLKL in echinoderms.
    PLoS Pathog. 2025;21:e1012991.
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  141. HILDEBRAND JA, Daniels NR, Dehm EM, Fisher BD, et al
    Severe malaria enforces short-lived effector cell differentiation but does not prevent effective secondary responses by memory CD8 T cells.
    PLoS Pathog. 2025;21:e1012993.
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  142. XU Q, Liu X, Heng H, Wang H, et al
    Myeloid-derived suppressor cell inhibits T-cell-based defense against Klebsiella pneumoniae infection via IDO1 production.
    PLoS Pathog. 2025;21:e1012979.
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  143. WANG Z, Jiang Z, Cao Q, Jia C, et al
    A genomic and phenotypic investigation of pigeon-adaptive Salmonella.
    PLoS Pathog. 2025;21:e1012992.
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  144. SAPOSNIK L, Coria LM, Bruno L, Guaimas FF, et al
    Ecotin protects Salmonella Typhimurium against the microbicidal activity of host proteases.
    PLoS Pathog. 2025;21:e1013013.
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  145. VIZARRAGA D, Kawamoto A, Marcos-Silva M, Martin J, et al
    Dynamics of the adhesion complex of the human pathogens Mycoplasma pneumoniae and Mycoplasma genitalium.
    PLoS Pathog. 2025;21:e1012973.
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    February 2025
  146. SILMON DE MONERRI NC, Che Y, Lees JA, Jasti J, et al
    Structure-based design of an immunogenic, conformationally stabilized FimH antigen for a urinary tract infection vaccine.
    PLoS Pathog. 2025;21:e1012325.
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  147. BERCUSSON A, Williams TJ, Simmonds NJ, Alton EW, et al
    Increased NFAT and NFkappaB signalling contribute to the hyperinflammatory phenotype in response to Aspergillus fumigatus in a mouse model of cystic fibrosis.
    PLoS Pathog. 2025;21:e1012784.
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  148. ZHANG Y, Gu Z, Li Z, Wu Q, et al
    Streptococcus mutans regulates ubiquitin modification of Candida albicans in the bacterial-fungal interaction.
    PLoS Pathog. 2025;21:e1012887.
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  149. MAMMERI H, Sereme Y, Toumi E, Faury H, et al
    Interplay between porin deficiency, fitness, and virulence in carbapenem-non-susceptible Pseudomonas aeruginosa and Enterobacteriaceae.
    PLoS Pathog. 2025;21:e1012902.
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  150. YANG S, Yu J, Dong X, Zeng J, et al
    CCR2 signaling regulates anti-chlamydia T cell immune responses in the airway.
    PLoS Pathog. 2025;21:e1012912.
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  151. PONT S, Nilly F, Berry L, Bonhoure A, et al
    Intracellular Pseudomonas aeruginosa persist and evade antibiotic treatment in a wound infection model.
    PLoS Pathog. 2025;21:e1012922.
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  152. GUPTA AK, Wang T, Mann A, Piguet V, et al
    Mechanisms of resistance against allylamine and azole antifungals in Trichophyton: A renewed call for innovative molecular diagnostics in susceptibility testing.
    PLoS Pathog. 2025;21:e1012913.
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  153. KANELLOPOULOS SG, Snelders E
    Moving beyond multi-triazole to multi-fungicide resistance: Broader selection of drug resistance in the human fungal pathogen Aspergillus fumigatus.
    PLoS Pathog. 2025;21:e1012851.
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  154. OLEA-OZUNA RJ, Campbell MJ, Quintanilla SY, Nandy S, et al
    Alternative lipid synthesis in response to phosphate limitation promotes antibiotic tolerance in Gram-negative ESKAPE pathogens.
    PLoS Pathog. 2025;21:e1012933.
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  155. WAGNER AS, Smith FM, Bennin DA, Votava JA, et al
    GATA1-deficient human pluripotent stem cells generate neutrophils with improved antifungal immunity that is mediated by the integrin CD18.
    PLoS Pathog. 2025;21:e1012654.
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  156. SWEENEY MI, Carranza CE, Tobin DM
    Understanding Mycobacterium tuberculosis through its genomic diversity and evolution.
    PLoS Pathog. 2025;21:e1012956.
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    January 2025
  157. DEL OLMO V, Redondo-Rio A, Garcia AB, Limtong S, et al
    Insights into the origin, hybridisation and adaptation of Candida metapsilosis hybrid pathogens.
    PLoS Pathog. 2025;21:e1012864.
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  158. AUGENSTREICH J, Phan AT, Allen CNS, Poddar A, et al
    Dynamic interplay of autophagy and membrane repair during Mycobacterium tuberculosis Infection.
    PLoS Pathog. 2025;21:e1012830.
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  159. WANG T, Yang H, Sheng Q, Ding Y, et al
    Isoferulic acid facilitates effective clearance of hypervirulent Klebsiella pneumoniae through targeting capsule.
    PLoS Pathog. 2025;21:e1012787.
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  160. SINGH P, Bankhead T
    Breaking a barrier: In trans vlsE recombination and genetic manipulation of the native vlsE gene of the Lyme disease pathogen.
    PLoS Pathog. 2025;21:e1012871.
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  161. BOTTING JM, Rahman MK, Xu H, Yue J, et al
    FlbB forms a distinctive ring essential for periplasmic flagellar assembly and motility in Borrelia burgdorferi.
    PLoS Pathog. 2025;21:e1012812.
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  162. MALIK HS, Bliska JB
    Guards and decoys: RIPoptosome and inflammasome pathway regulators of bacterial effector-triggered immunity.
    PLoS Pathog. 2025;21:e1012884.
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  163. CHEN Z, Jin Q, Zhong J, Xie Z, et al
    Staphylococcus aureus blocks host autophagy through circSyk/miR-5106/Sik3 axis to promote progression of bone infection.
    PLoS Pathog. 2025;21:e1012896.
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  164. WIDZIOLEK M, Mieszkowska A, Marcinkowska M, Salamaga B, et al
    Gingipains protect Porphyromonas gingivalis from macrophage-mediated phagocytic clearance.
    PLoS Pathog. 2025;21:e1012821.
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  165. EMONS M, Blanquart F, Lehtinen S
    The evolution of antibiotic resistance in Europe, 1998-2019.
    PLoS Pathog. 2025;21:e1012945.
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    December 2024
  166. WANG S, Li XY, Zhu M, Deng H, et al
    The SpxA1-TenA toxin-antitoxin system regulates epigenetic variations of Streptococcus pneumoniae by targeting protein synthesis.
    PLoS Pathog. 2024;20:e1012801.
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  167. DAY AM, Cao M, Dantas ADS, Ianieva O, et al
    Stress contingent changes in Hog1 pathway architecture and regulation in Candida albicans.
    PLoS Pathog. 2024;20:e1012314.
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  168. JAYAKUMAR JM, Martinez-Urtaza J, Brumfield KD, Jutla AS, et al
    Climate change and Vibrio vulnificus dynamics: A blueprint for infectious diseases.
    PLoS Pathog. 2024;20:e1012767.
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  169. CHILDERS DS, Usher J
    Is metabolic generalism the Breakfast of Champions for pathogenic Candida species?
    PLoS Pathog. 2024;20:e1012752.
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  170. GUPTA D, Shukla R, Mishra K
    SUMO-targeted Ubiquitin Ligases as crucial mediators of protein homeostasis in Candida glabrata.
    PLoS Pathog. 2024;20:e1012742.
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  171. LIU Y, Xu D, Guo S, Wang S, et al
    The gut microbiota-independent virulence of noninvasive bacterial pathogen Citrobacter rodentium.
    PLoS Pathog. 2024;20:e1012758.
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  172. WEERASEKERA R, Moreau A, Huang X, Nam KM, et al
    Vibrio cholerae RbmB is an alpha-1,4-polysaccharide lyase with biofilm-disrupting activity against Vibrio polysaccharide (VPS).
    PLoS Pathog. 2024;20:e1012750.
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  173. ANBO M, Lubna MA, Moustafa DA, Paiva TO, et al
    Serotype switching in Pseudomonas aeruginosa ST111 enhances adhesion and virulence.
    PLoS Pathog. 2024;20:e1012221.
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  174. ALFAIFI AA, Wang TW, Perez P, Sultan AS, et al
    SARS-CoV-2 infection of salivary glands compromises the production of a secreted antifungal peptide with potential implications for development of oral candidiasis.
    PLoS Pathog. 2024;20:e1012375.
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  175. RAGHUNANDANAN S, Zhang K, Zhang Y, Priya R, et al
    MCP5, a methyl-accepting chemotaxis protein regulated by both the Hk1-Rrp1 and Rrp2-RpoN-RpoS pathways, is required for the immune evasion of Borrelia burgdorferi.
    PLoS Pathog. 2024;20:e1012327.
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  176. NASHIER P, Samp I, Adler M, Ebner F, et al
    Deep phosphoproteomics of Klebsiella pneumoniae reveals HipA-mediated tolerance to ciprofloxacin.
    PLoS Pathog. 2024;20:e1012759.
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  177. LOPEZ-ARGUELLO S, Alcoceba E, Ordonez P, Taltavull B, et al
    Differential contribution of PBP occupancy and efflux on the effectiveness of beta-lactams at their target site in clinical isolates of Neisseria gonorrhoeae.
    PLoS Pathog. 2024;20:e1012783.
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  178. DELGADO KN, Caimano MJ, Orbe IC, Vicente CF, et al
    Immunodominant extracellular loops of Treponema pallidum FadL outer membrane proteins elicit antibodies with opsonic and growth-inhibitory activities.
    PLoS Pathog. 2024;20:e1012443.
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    November 2024
  179. TAN W, Liu J, Yu R, Zhao P, et al
    Trim72 is a major host factor protecting against lethal Candida albicans infection.
    PLoS Pathog. 2024;20:e1012747.
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  180. BALAKUMAR A, Das D, Datta A, Mishra A, et al
    Single-cell transcriptomics unveils skin cell specific antifungal immune responses and IL-1Ra- IL-1R immune evasion strategies of emerging fungal pathogen Candida auris.
    PLoS Pathog. 2024;20:e1012699.
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  181. MORSCHHAUSER J
    Adaptation of Candida albicans to specific host environments by gain-of-function mutations in transcription factors.
    PLoS Pathog. 2024;20:e1012643.
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  182. WANG C, Wen J, Yan Z, Zhou Y, et al
    Suppressing neutrophil itaconate production attenuates Mycoplasma pneumoniae pneumonia.
    PLoS Pathog. 2024;20:e1012614.
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  183. JONES RA, Ramirez-Bencomo F, Whiting G, Fang M, et al
    Tackling immunosuppression by Neisseria gonorrhoeae to facilitate vaccine design.
    PLoS Pathog. 2024;20:e1012688.
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  184. BISARO F, Jackson-Litteken CD, McGuffey JC, Hooppaw AJ, et al
    Diclofenac sensitizes multi-drug resistant Acinetobacter baumannii to colistin.
    PLoS Pathog. 2024;20:e1012705.
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  185. PETERSON PP, Choi JT, Fu C, Cowen LE, et al
    The Cryptococcus neoformans STRIPAK complex controls genome stability, sexual development, and virulence.
    PLoS Pathog. 2024;20:e1012735.
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  186. ZHANG H, Sheng S, Li C, Bao X, et al
    Mucosal immunization with the lung Lactobacillus-derived amphiphilic exopolysaccharide adjuvanted recombinant vaccine improved protection against P. aeruginosa infection.
    PLoS Pathog. 2024;20:e1012696.
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  187. GELGIE AE, Schneider P, Citti C, Dordet-Frisoni E, et al
    Mycoplasma bovis 5'-nucleotidase is a virulence factor conferring mammary fitness in bovine mastitis.
    PLoS Pathog. 2024;20:e1012628.
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    October 2024
  188. PEIGNIER A, Kim J, Lemenze A, Parker D, et al
    Monocyte-regulated interleukin 12 production drives clearance of Staphylococcus aureus.
    PLoS Pathog. 2024;20:e1012648.
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  189. SANKAR P, Ramos RB, Corro J, Mishra LK, et al
    Fatty acid metabolism in neutrophils promotes lung damage and bacterial replication during tuberculosis.
    PLoS Pathog. 2024;20:e1012188.
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  190. DE LAY NR, Verma N, Sinha D, Garrett A, et al
    The five homologous CiaR-controlled Ccn sRNAs of Streptococcus pneumoniae modulate Zn-resistance.
    PLoS Pathog. 2024;20:e1012165.
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  191. SARATHY JP
    Molecular and microbiological methods for the identification of nonreplicating Mycobacterium tuberculosis.
    PLoS Pathog. 2024;20:e1012595.
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  192. PHAN-CANH T, Kuchler K
    Do morphogenetic switching and intraspecies variation enhance virulence of Candida auris?
    PLoS Pathog. 2024;20:e1012559.
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  193. WALE KR, O'Boyle N, McHugh RE, Serrano E, et al
    A master regulator of central carbon metabolism directly activates virulence gene expression in attaching and effacing pathogens.
    PLoS Pathog. 2024;20:e1012451.
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  194. SCHLOTZER J, Schmalix A, Hugelschaffer S, Rieger D, et al
    Linkage-specific ubiquitin binding interfaces modulate the activity of the chlamydial deubiquitinase Cdu1 towards poly-ubiquitin substrates.
    PLoS Pathog. 2024;20:e1012630.
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  195. BRADY A, Mora Martinez LC, Hammond B, Whitefoot-Keliin KM, et al
    Distinct mechanisms of type 3 secretion system recognition control LTB4 synthesis in neutrophils and macrophages.
    PLoS Pathog. 2024;20:e1012651.
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  196. KELLY M, Cuomo CA, Beukema W, Carranza S, et al
    High phenotypic diversity correlated with genomic variation across the European Batrachochytrium salamandrivorans epizootic.
    PLoS Pathog. 2024;20:e1012579.
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  197. WANG L, Wang Z, Zhang H, Jin Q, et al
    A novel esterase regulates Klebsiella pneumoniae hypermucoviscosity and virulence.
    PLoS Pathog. 2024;20:e1012675.
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  198. WATERS EV, Lee WWY, Ismail Ahmed A, Chattaway MA, et al
    From acute to persistent infection: revealing phylogenomic variations in Salmonella Agona.
    PLoS Pathog. 2024;20:e1012679.
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    September 2024
  199. DAS MK, Savidge B, Pearl JE, Yates T, et al
    Altered hepatic metabolic landscape and insulin sensitivity in response to pulmonary tuberculosis.
    PLoS Pathog. 2024;20:e1012565.
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  200. HASSOUN Y, Aptekmann AA, Keniya MV, Gomez RY, et al
    Evolutionary dynamics in gut-colonizing Candida glabrata during caspofungin therapy: Emergence of clinically important mutations in sphingolipid biosynthesis.
    PLoS Pathog. 2024;20:e1012521.
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  201. DESPRES PC, Shapiro RS, Cuomo CA
    New approaches to tackle a rising problem: Large-scale methods to study antifungal resistance.
    PLoS Pathog. 2024;20:e1012478.
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  202. GUO M, Li Y, Tang J, Wang Q, et al
    Glaesserella parasuis serotype 4 exploits fibronectin via RlpA for tracheal colonization following porcine circovirus type 2 infection.
    PLoS Pathog. 2024;20:e1012513.
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  203. MURANTE D, Hogan DA
    Drivers of diversification in fungal pathogen populations.
    PLoS Pathog. 2024;20:e1012430.
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  204. ALEXANDER NG, Cutts WD, Hooven TA, Kim BJ, et al
    Transcription modulation of pathogenic streptococcal and enterococcal species using CRISPRi technology.
    PLoS Pathog. 2024;20:e1012520.
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  205. PETERSON E, Soderstrom B, Prins N, Le GHB, et al
    The role of bacterial size, shape and surface in macrophage engulfment of uropathogenic E. coli cells.
    PLoS Pathog. 2024;20:e1012458.
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  206. HARKOVA LG, de Dios R, Rubio-Valle A, Perez-Pulido AJ, et al
    Cyclic AMP is a global virulence regulator governing inter and intrabacterial signalling in Acinetobacter baumannii.
    PLoS Pathog. 2024;20:e1012529.
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  207. WANG Y, Wang KM, Zhang X, Wang W, et al
    Stenotrophomonas maltophilia uses a c-di-GMP module to sense the mammalian body temperature during infection.
    PLoS Pathog. 2024;20:e1012533.
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  208. LUO X, Zhang L, Xie X, Yuan L, et al
    Phosphorylated vimentin-triggered fibronectin matrix disaggregation enhances the dissemination of Treponema pallidum subsp. pallidum across the microvascular endothelial barrier.
    PLoS Pathog. 2024;20:e1012483.
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  209. DIERICK E, Callens C, Bloch Y, Savvides SN, et al
    Clostridium perfringens chitinases, key enzymes during early stages of necrotic enteritis in broiler chickens.
    PLoS Pathog. 2024;20:e1012560.
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  210. SCHMIDT S, Mondino S, Gomez-Valero L, Escoll P, et al
    The unique Legionella longbeachae capsule favors intracellular replication and immune evasion.
    PLoS Pathog. 2024;20:e1012534.
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  211. MEYEROWITZ EA, Liang R, Bishop D, Mullis CE, et al
    Put a little doxy-PEP in your step: Using doxycycline to prevent chlamydia, syphilis, and gonorrhea infections.
    PLoS Pathog. 2024;20:e1012575.
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  212. RODRIGUEZ-PASTOR R, Knossow N, Shahar N, Hasik AZ, et al
    Pathogen contingency loci and the evolution of host specificity: Simple sequence repeats mediate Bartonella adaptation to a wild rodent host.
    PLoS Pathog. 2024;20:e1012591.
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  213. WALTMANN A, Balthazar JT, Begum AA, Hua N, et al
    Experimental genital tract infection demonstrates Neisseria gonorrhoeae MtrCDE efflux pump is not required for in vivo human infection and identifies gonococcal colonization bottleneck.
    PLoS Pathog. 2024;20:e1012578.
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  214. LEONIDOU N, Xia Y, Friedrich L, Schutz MS, et al
    Exploring the metabolic profile of A. baumannii for antimicrobial development using genome-scale modeling.
    PLoS Pathog. 2024;20:e1012528.
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  215. NABUKHOTNA K, Kordus SL, Shupe JA, Cano Rodriguez R, et al
    Purified CDT toxins and a clean deletion within the CDT locus provide novel insights into the contribution of binary toxin in cellular inflammation and Clostridioides difficile infection.
    PLoS Pathog. 2024;20:e1012568.
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  216. BERNDSEN ZT, Akhtar M, Thapa M, Vickers TJ, et al
    Repeat modules and N-linked glycans define structure and antigenicity of a critical enterotoxigenic E. coli adhesin.
    PLoS Pathog. 2024;20:e1012241.
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  217. ISHIKAWA-ANKERHOLD H, Busch B, Bader A, Maier-Begandt D, et al
    Novel multiphoton intravital imaging enables real-time study of Helicobacter pylori interaction with neutrophils and macrophages in the mouse stomach.
    PLoS Pathog. 2024;20:e1012580.
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    August 2024
  218. VANDE ZANDE P, Gautier C, Kawar N, Maufrais C, et al
    Step-wise evolution of azole resistance through copy number variation followed by KSR1 loss of heterozygosity in Candida albicans.
    PLoS Pathog. 2024;20:e1012497.
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  219. CHOI E, Choi HH, Kwon KW, Kim H, et al
    Permissive lung neutrophils facilitate tuberculosis immunopathogenesis in male phagocyte NADPH oxidase-deficient mice.
    PLoS Pathog. 2024;20:e1012500.
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  220. CRESTANI C, Forde TL, Bell J, Lycett SJ, et al
    Genomic and functional determinants of host spectrum in Group B Streptococcus.
    PLoS Pathog. 2024;20:e1012400.
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  221. JIN M, Wu X, Hu J, Chen Y, et al
    EGFR-MEK1/2 cascade negatively regulates bactericidal function of bone marrow macrophages in mice with Staphylococcus aureus osteomyelitis.
    PLoS Pathog. 2024;20:e1012437.
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  222. HOVHANNISYAN P, Stelzner K, Keicher M, Paprotka K, et al
    Infection of human organoids supports an intestinal niche for Chlamydia trachomatis.
    PLoS Pathog. 2024;20:e1012144.
    >> Share

  223. DARBY AM, Okoro DO, Aredas S, Frank AM, et al
    High sugar diets can increase susceptibility to bacterial infection in Drosophila melanogaster.
    PLoS Pathog. 2024;20:e1012447.
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  224. BLECHMAN SE, Wright ES
    Vancomycin-resistant Staphylococcus aureus (VRSA) can overcome the cost of antibiotic resistance and may threaten vancomycin's clinical durability.
    PLoS Pathog. 2024;20:e1012422.
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  225. ISIDORO-AYZA M, Lorch JM, Klein BS
    The skin I live in: Pathogenesis of white-nose syndrome of bats.
    PLoS Pathog. 2024;20:e1012342.
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  226. PIDOT SJ, Klatt S, Ates LS, Frigui W, et al
    Marine sponge microbe provides insights into evolution and virulence of the tubercle bacillus.
    PLoS Pathog. 2024;20:e1012440.
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  227. BARBIEUX E, Potemberg G, Stubbe FX, Fraikin A, et al
    Genome-wide analysis of Brucella melitensis growth in spleen of infected mice allows rational selection of new vaccine candidates.
    PLoS Pathog. 2024;20:e1012459.
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  228. CERVONI M, Sposato D, Ferri G, Bahre H, et al
    The diadenosine tetraphosphate hydrolase ApaH contributes to Pseudomonas aeruginosa pathogenicity.
    PLoS Pathog. 2024;20:e1012486.
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  229. MEYER I, Volk M, Salto I, Moesser T, et al
    RNase-mediated reprogramming of Yersinia virulence.
    PLoS Pathog. 2024;20:e1011965.
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  230. GUO M, Li X, Tao W, Teng F, et al
    Vibrio splendidus infection promotes circRNA-FGL1-regulated coelomocyte apoptosis via competitive binding to Myc with the deubiquitinase OTUB1 in Apostichopus japonicus.
    PLoS Pathog. 2024;20:e1012463.
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  231. MURTHA AN, Kazi MI, Kim EY, Torres FV, et al
    Multiple resistance factors collectively promote inoculum-dependent dynamic survival during antimicrobial peptide exposure in Enterobacter cloacae.
    PLoS Pathog. 2024;20:e1012488.
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  232. PARK JE, Yun JH, Lee W, Lee JS, et al
    C-ter100 peptide derived from Vibrio vEP-45 protease acts as a pathogen-associated molecular pattern to induce inflammation and innate immunity.
    PLoS Pathog. 2024;20:e1012474.
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  233. MOBLEY HLT, Anderson MT, Moricz BS, Severin GB, et al
    Fitness factor genes conserved within the multi-species core genome of Gram-negative Enterobacterales species contribute to bacteremia pathogenesis.
    PLoS Pathog. 2024;20:e1012495.
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  234. ANTOS D, Parks OB, Duray AM, Abraham N, et al
    Cell-intrinsic regulation of phagocyte function by interferon lambda during pulmonary viral, bacterial super-infection.
    PLoS Pathog. 2024;20:e1012498.
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  235. LANG JC, Brutscher A, Ehrstrom M, Melican K, et al
    Tissue resident cells differentiate S. aureus from S. epidermidis via IL-1beta following barrier disruption in healthy human skin.
    PLoS Pathog. 2024;20:e1012056.
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    July 2024
  236. CHEN F, Zhao Q, Yang Z, Chen R, et al
    Citrate serves as a signal molecule to modulate carbon metabolism and iron homeostasis in Staphylococcus aureus.
    PLoS Pathog. 2024;20:e1012425.
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  237. YEBRA G, Mrochen D, Fischer S, Pfaff F, et al
    Bacteriophage-driven emergence and expansion of Staphylococcus aureus in rodent populations.
    PLoS Pathog. 2024;20:e1012378.
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  238. LONG DR, Holmes EA, Lo HY, Penewit K, et al
    Clinical and in vitro models identify distinct adaptations enhancing Staphylococcus aureus pathogenesis in human macrophages.
    PLoS Pathog. 2024;20:e1012394.
    >> Share

  239. DENG Y, Xu M, Li S, Bing J, et al
    A single gene mutation underpins metabolic adaptation and acquisition of filamentous competence in the emerging fungal pathogen Candida auris.
    PLoS Pathog. 2024;20:e1012362.
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  240. AGGOR FEY, Bertolini M, Coleman BM, Taylor TC, et al
    Combinatorial actions of IL-22 and IL-17 drive optimal immunity to oral candidiasis through SPRRs.
    PLoS Pathog. 2024;20:e1012302.
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  241. YUAN J, Yu Y, Li S, Zhang X, et al
    Shrimp shapes a resistance trait against vibriosis by memorizing the colonization resistance of intestinal microbiota.
    PLoS Pathog. 2024;20:e1012321.
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  242. AGRAWAL R, de Castro RJA, Sturny-Leclere A, Alanio A, et al
    Population heterogeneity in Cryptococcus neoformans: Impact on pathogenesis.
    PLoS Pathog. 2024;20:e1012332.
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  243. KAPPLER U, Henningham A, Nasreen M, Yamamoto A, et al
    Tolerance to Haemophilus influenzae infection in human epithelial cells: Insights from a primary cell-based model.
    PLoS Pathog. 2024;20:e1012282.
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  244. PERRIER M, Barber AE
    Unraveling the genomic diversity and virulence of human fungal pathogens through pangenomics.
    PLoS Pathog. 2024;20:e1012313.
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  245. MCKAY LS, Spandrio AR, Johnson RM, Sobran MA, et al
    Cytochrome oxidase requirements in Bordetella reveal insights into evolution towards life in the mammalian respiratory tract.
    PLoS Pathog. 2024;20:e1012084.
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  246. POTTER AD, Edwards VL, D'Mello A, Gray MC, et al
    Dual species transcriptomics reveals conserved metabolic and immunologic processes in interactions between human neutrophils and Neisseria gonorrhoeae.
    PLoS Pathog. 2024;20:e1012369.
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  247. WANG R, Oliveira LVN, Hester MM, Carlson D, et al
    Protection against experimental cryptococcosis elicited by Cationic Adjuvant Formulation 01-adjuvanted subunit vaccines.
    PLoS Pathog. 2024;20:e1012220.
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  248. KIM SY, Choi JA, Choi S, Kim KK, et al
    Advances in an In Vitro Tuberculosis Infection Model Using Human Lung Organoids for Host-Directed Therapies.
    PLoS Pathog. 2024;20:e1012295.
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  249. ZHONG X, Liu F, Liang T, Lu R, et al
    The two-component system TtrRS boosts Vibrio parahaemolyticus colonization by exploiting sulfur compounds in host gut.
    PLoS Pathog. 2024;20:e1012410.
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  250. GIRAUD-GATINEAU A, Nieves C, Harrison LB, Benaroudj N, et al
    Evolutionary insights into the emergence of virulent Leptospira spirochetes.
    PLoS Pathog. 2024;20:e1012161.
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  251. ZHOU X, Hilk A, Solis NV, Pereira De Sa N, et al
    Erg251 has complex and pleiotropic effects on sterol composition, azole susceptibility, filamentation, and stress response phenotypes.
    PLoS Pathog. 2024;20:e1012389.
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    June 2024
  252. HEILIG L, Natasha F, Trinks N, Aimanianda V, et al
    CD56-mediated activation of human natural killer cells is triggered by Aspergillus fumigatus galactosaminogalactan.
    PLoS Pathog. 2024;20:e1012315.
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  253. TSENG KY, Huang YT, Huang YT, Su YT, et al
    Regulation of candidalysin underlies Candida albicans persistence in intravascular catheters by modulating NETosis.
    PLoS Pathog. 2024;20:e1012319.
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  254. EKKA R, Gutierrez A, Johnson KA, Tan M, et al
    Chlamydia trachomatis induces disassembly of the primary cilium to promote the intracellular infection.
    PLoS Pathog. 2024;20:e1012303.
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  255. GATTI DM, Tyler AL, Mahoney JM, Churchill GA, et al
    Systems genetics uncover new loci containing functional gene candidates in Mycobacterium tuberculosis-infected Diversity Outbred mice.
    PLoS Pathog. 2024;20:e1011915.
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  256. CULLUM E, Perez-Betancourt Y, Shi M, Gkika E, et al
    Deficiency in non-classical major histocompatibility class II-like molecule, H2-O confers protection against Staphylococcus aureus in mice.
    PLoS Pathog. 2024;20:e1012306.
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  257. DULYAYANGKUL P, Beavis T, Lee WWY, Ardagh R, et al
    Harvesting and amplifying gene cassettes confers cross-resistance to critically important antibiotics.
    PLoS Pathog. 2024;20:e1012235.
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  258. KELLY JB, Nolan AC, Zeden MS
    How can we escape the ESKAPEs: Antimicrobial resistance mechanisms and what lies ahead?
    PLoS Pathog. 2024;20:e1012270.
    >> Share

  259. DELLIERE S, Jabet A, Abdolrasouli A
    Current and emerging issues in dermatophyte infections.
    PLoS Pathog. 2024;20:e1012258.
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  260. CHEN J, Lin G, Ma K, Li Z, et al
    A specific innate immune response silences the virulence of Pseudomonas aeruginosa in a latent infection model in the Drosophila melanogaster host.
    PLoS Pathog. 2024;20:e1012252.
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  261. PRAKASH A, Fenner F, Shit B, Salminen TS, et al
    IMD-mediated innate immune priming increases Drosophila survival and reduces pathogen transmission.
    PLoS Pathog. 2024;20:e1012308.
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  262. ZHANG Y, Li B, Hong Y, Luo P, et al
    Histone demethylase JMJD2D protects against enteric bacterial infection via up-regulating colonic IL-17F to induce beta-defensin expression.
    PLoS Pathog. 2024;20:e1012316.
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    May 2024
  263. XIONG L, Pereira De Sa N, Zarnowski R, Huang MY, et al
    Biofilm-associated metabolism via ERG251 in Candida albicans.
    PLoS Pathog. 2024;20:e1012225.
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  264. ZHENG W, Chang IC, Limberis J, Budzik JM, et al
    Mycobacterium tuberculosis resides in lysosome-poor monocyte-derived lung cells during chronic infection.
    PLoS Pathog. 2024;20:e1012205.
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  265. WINDELS EM, Wampande EM, Joloba ML, Boom WH, et al
    HIV co-infection is associated with reduced Mycobacterium tuberculosis transmissibility in sub-Saharan Africa.
    PLoS Pathog. 2024;20:e1011675.
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  266. JIANG B, Lai Y, Xiao W, Zhong T, et al
    Microbial extracellular vesicles contribute to antimicrobial resistance.
    PLoS Pathog. 2024;20:e1012143.
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  267. VANKAYALAPATI A, Durojaye O, Mukherjee T, Paidipally P, et al
    Metabolic changes enhance necroptosis of type 2 diabetes mellitus mice infected with Mycobacterium tuberculosis.
    PLoS Pathog. 2024;20:e1012148.
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  268. ZANG X, Zhang J, Jiang Y, Feng T, et al
    Serine protease Rv2569c facilitates transmission of Mycobacterium tuberculosis via disrupting the epithelial barrier by cleaving E-cadherin.
    PLoS Pathog. 2024;20:e1012214.
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  269. LOKKEN-TOYLI KL, Aggarwal SD, Bee GCW, de Steenhuijsen Piters WAA, et al
    Impaired upper respiratory tract barrier function during postnatal development predisposes to invasive pneumococcal disease.
    PLoS Pathog. 2024;20:e1012111.
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  270. BAI Y, Xie C, Zhang Y, Zhang Z, et al
    sRNA expression profile of KPC-2-producing carbapenem-resistant Klebsiella pneumoniae: Functional role of sRNA51.
    PLoS Pathog. 2024;20:e1012187.
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  271. BARNES AJ, Bennett EF, Vezina B, Hudson AW, et al
    Ethanolamine metabolism through two genetically distinct loci enables Klebsiella pneumoniae to bypass nutritional competition in the gut.
    PLoS Pathog. 2024;20:e1012189.
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  272. WACKER T, Helmstetter N, Studholme DJ, Farrer RA, et al
    Genome variation in the Batrachochytrium pathogens of amphibians.
    PLoS Pathog. 2024;20:e1012218.
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  273. LIANG Y, Wang H, Sun K, Sun J, et al
    Lack of the IFN-gamma signal leads to lethal Orientia tsutsugamushi infection in mice with skin eschar lesions.
    PLoS Pathog. 2024;20:e1012020.
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  274. DICANDIA MA, Edwards AN, Alcaraz YB, Monteiro MP, et al
    A conserved switch controls virulence, sporulation, and motility in C. difficile.
    PLoS Pathog. 2024;20:e1012224.
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  275. LI C, Fu J, Shao S, Luo ZQ, et al
    Legionella pneumophila exploits the endo-lysosomal network for phagosome biogenesis by co-opting SUMOylated Rab7.
    PLoS Pathog. 2024;20:e1011783.
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  276. WILLIAMS SL, Toda M, Chiller T, Brunkard JM, et al
    Effects of climate change on fungal infections.
    PLoS Pathog. 2024;20:e1012219.
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  277. PAN Q, Zhang Y, Liu T, Xu Q, et al
    Mycoplasma glycine cleavage system key subunit GcvH is an apoptosis inhibitor targeting host endoplasmic reticulum.
    PLoS Pathog. 2024;20:e1012266.
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  278. RAPSINSKI GJ, Michaels LA, Hill M, Yarrington KD, et al
    Pseudomonas aeruginosa senses and responds to epithelial potassium flux via Kdp operon to promote biofilm.
    PLoS Pathog. 2024;20:e1011453.
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    April 2024
  279. SANGKLAI N, Supungul P, Jaroenlak P, Tassanakajon A, et al
    Immune signaling of Litopenaeus vannamei c-type lysozyme and its role during microsporidian Enterocytozoon hepatopenaei (EHP) infection.
    PLoS Pathog. 2024;20:e1012199.
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  280. GU Q, Zhu X, Yu Y, Jiang T, et al
    Type II and IV toxin-antitoxin systems coordinately stabilize the integrative and conjugative element of the ICESa2603 family conferring multiple drug resistance in Streptococcus suis.
    PLoS Pathog. 2024;20:e1012169.
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  281. YOUNGBLOM MA, Smith TM, Murray HJ, Pepperell CS, et al
    Adaptation of the Mycobacterium tuberculosis transcriptome to biofilm growth.
    PLoS Pathog. 2024;20:e1012124.
    >> Share

  282. LI J, Ma Q, Huang J, Liu Y, et al
    Small RNA SmsR1 modulates acidogenicity and cariogenic virulence by affecting protein acetylation in Streptococcus mutans.
    PLoS Pathog. 2024;20:e1012147.
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  283. BOBBA S, Chauhan KS, Akter S, Das S, et al
    A protective role for type I interferon signaling following infection with Mycobacterium tuberculosis carrying the rifampicin drug resistance-conferring RpoB mutation H445Y.
    PLoS Pathog. 2024;20:e1012137.
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  284. GNAIEN M, Maufrais C, Rebai Y, Kallel A, et al
    A gain-of-function mutation in zinc cluster transcription factor Rob1 Drives Candida albicans adaptive growth in the cystic fibrosis lung environment.
    PLoS Pathog. 2024;20:e1012154.
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  285. FULLER NM, McQuaid CF, Harker MJ, Weerasuriya CK, et al
    Mathematical models of drug-resistant tuberculosis lack bacterial heterogeneity: A systematic review.
    PLoS Pathog. 2024;20:e1011574.
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  286. CALDERON-GONZALEZ R, Dumigan A, Sa-Pessoa J, Kissenpfennig A, et al
    In vivo single-cell high-dimensional mass cytometry analysis to track the interactions between Klebsiella pneumoniae and myeloid cells.
    PLoS Pathog. 2024;20:e1011900.
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  287. FAITH DR, Kinnersley M, Brooks DM, Drecktrah D, et al
    Characterization and genomic analysis of the Lyme disease spirochete bacteriophage varphiBB-1.
    PLoS Pathog. 2024;20:e1012122.
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    March 2024
  288. BLOCK AM, Wiegert PC, Namugenyi SB, Tischler AD, et al
    Transposon sequencing reveals metabolic pathways essential for Mycobacterium tuberculosis infection.
    PLoS Pathog. 2024;20:e1011663.
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  289. PELLETIER C, Shaw S, Alsayegh S, Brown AJP, et al
    Candida auris undergoes adhesin-dependent and -independent cellular aggregation.
    PLoS Pathog. 2024;20:e1012076.
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  290. SHANNON BA, Hurst JR, Flannagan RS, Craig HC, et al
    Streptolysin S is required for Streptococcus pyogenes nasopharyngeal and skin infection in HLA-transgenic mice.
    PLoS Pathog. 2024;20:e1012072.
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  291. KURTZ SL, Baker RE, Boehm FJ, Lehman CC, et al
    Multiple genetic loci influence vaccine-induced protection against Mycobacterium tuberculosis in genetically diverse mice.
    PLoS Pathog. 2024;20:e1012069.
    >> Share

  292. SPRAGUE JL, Schille TB, Allert S, Trumper V, et al
    Candida albicans translocation through the intestinal epithelial barrier is promoted by fungal zinc acquisition and limited by NFkappaB-mediated barrier protection.
    PLoS Pathog. 2024;20:e1012031.
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  293. SANTANA DJ, Zhao G, O'Meara TR
    The many faces of Candida auris: Phenotypic and strain variation in an emerging pathogen.
    PLoS Pathog. 2024;20:e1012011.
    >> Share

  294. DENNING DW
    Renaming Candida glabrata-A case of taxonomic purity over clinical and public health pragmatism.
    PLoS Pathog. 2024;20:e1012055.
    >> Share

  295. ANGGRAMUKTI DS, Ishii E, Pratama A, Al Kadi M, et al
    The read-through transcription-mediated autoactivation circuit for virulence regulator expression drives robust type III secretion system 2 expression in Vibrio parahaemolyticus.
    PLoS Pathog. 2024;20:e1012094.
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    February 2024
  296. STANLEY S, Wang X, Liu Q, Kwon YY, et al
    Ongoing evolution of the Mycobacterium tuberculosis lactate dehydrogenase reveals the pleiotropic effects of bacterial adaption to host pressure.
    PLoS Pathog. 2024;20:e1012050.
    >> Share

  297. NGUYEN TT, Kim TH, Bencosme-Cuevas E, Berry J, et al
    A tick saliva serpin, IxsS17 inhibits host innate immune system proteases and enhances host colonization by Lyme disease agent.
    PLoS Pathog. 2024;20:e1012032.
    >> Share

    September 2023
  298. DADELAHI AS, Abushahba MFN, Ponzilacqua-Silva B, Chambers CA, et al
    Interactions between B cells and T follicular regulatory cells enhance susceptibility to Brucella infection independent of the anti-Brucella humoral response.
    PLoS Pathog. 2023;19:e1011672.
    >> Share


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