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Articles published in
Eur J Pharmacol
    April 2018
  1. LAN TH, Chen XL, Wu YS, Qiu HL, et al
    3,7-Bis(2-hydroxyethyl)icaritin, a potent inhibitor of phosphodiesterase-5, prevents monocrotaline-induced pulmonary arterial hypertension via NO/cGMP activation in rats.
    Eur J Pharmacol. 2018 Apr 14. pii: S0014-2999(18)30222.
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    February 2018
  2. BHAT L, Hawkinson J, Cantillon M, Reddy DG, et al
    Evaluation of the effects of RP5063, a novel, multimodal, serotonin receptor modulator, as single-agent therapy and co-administrated with sildenafil, bosentan, and treprostinil in a monocrotaline-induced pulmonary arterial hypertension rat model.
    Eur J Pharmacol. 2018 Feb 14. pii: S0014-2999(18)30096.
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    January 2018
  3. GONCALVES-RIZZI VH, Possomato-Vieira JS, Nascimento RA, Caldeira-Dias M, et al
    Maternal hypertension and feto-placental growth restriction is reversed by sildenafil: Evidence of independent effects of circulating nitric oxide levels.
    Eur J Pharmacol. 2018 Jan 17. pii: S0014-2999(18)30017.
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  4. MARTINS-OLIVEIRA A, Guimaraes DA, Ceron CS, Rizzi E, et al
    Direct renin inhibition is not enough to prevent reactive oxygen species generation and vascular dysfunction in renovascular hypertension.
    Eur J Pharmacol. 2018;821:97-104.
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    December 2017
  5. ZHANG N, Dong M, Luo Y, Zhao F, et al
    Danshensu prevents hypoxic pulmonary hypertension in rats by inhibiting the proliferation of pulmonary artery smooth muscle cells via TGF-beta-smad3-associated pathway.
    Eur J Pharmacol. 2017 Dec 5. pii: S0014-2999(17)30794.
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  6. LEBLANC C, Tabrizchi R
    Role of beta2- and beta3-adrenoceptors in arterial stiffness in a state of hypertension.
    Eur J Pharmacol. 2017 Dec 2. pii: S0014-2999(17)30783.
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    November 2017
  7. WU Y, Qian Z, Fu S, Yue Y, et al
    IcarisideII improves left ventricular remodeling in spontaneously hypertensive rats by inhibiting the ASK1-JNK/p38 signaling pathway.
    Eur J Pharmacol. 2017 Nov 21. pii: S0014-2999(17)30768.
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    October 2017
  8. ZHANG W, Zhu T, Wu W, Ge X, et al
    LOX-1 mediated phenotypic switching of pulmonary arterial smooth muscle cells contributes to hypoxic pulmonary hypertension.
    Eur J Pharmacol. 2017;818:84-95.
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    September 2017
  9. SUN P, Sun H, Zhang W, Du Z, et al
    Antagonist of thromboxane A2 receptor by SQ29548 lowers DOCA-induced hypertension in diabetic rats.
    Eur J Pharmacol. 2017 Sep 20. pii: S0014-2999(17)30614.
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    August 2017
  10. SILVA BR, Pernomian L, De Paula TD, Grando MD, et al
    Endothelial nitric oxide synthase and cyclooxygenase are activated by hydrogen peroxide in renal hypertensive rat aorta.
    Eur J Pharmacol. 2017 Aug 2. pii: S0014-2999(17)30503.
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    July 2017
  11. SINGH A, Kumar BS, Alam S, Iqbal H, et al
    Corrigendum to "Diethyl-4,4'-dihydroxy-8,3'-neolign-7,7'-dien-9,9'-dionate exhibits antihypertensive activity in rats through increase in intracellular cGMP level and blockade of calcium channels" [Eur. J. Pharmacol. 799 (2017) 84-93].
    Eur J Pharmacol. 2017;806:111.
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  12. JIANG D, Kawagoe Y, Kuwasako K, Kitamura K, et al
    Inhibitory effects of losartan and azelnidipine on augmentation of blood pressure variability induced by angiotensin II in rats.
    Eur J Pharmacol. 2017;806:91-95.
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    June 2017
  13. YAMAMURA A, Fujitomi E, Ohara N, Tsukamoto K, et al
    Tadalafil induces antiproliferation, apoptosis, and phosphodiesterase type 5 downregulation in idiopathic pulmonary arterial hypertension in vitro.
    Eur J Pharmacol. 2017 Jun 8. pii: S0014-2999(17)30400.
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    May 2017
  14. BHAT L, Hawkinson J, Cantillon M, Reddy DG, et al
    RP5063, a novel, multimodal, serotonin receptor modulator, prevents monocrotaline-induced pulmonary arterial hypertension in rats.
    Eur J Pharmacol. 2017 May 31. pii: S0014-2999(17)30380.
    >> Share

  15. BHAT L, Hawkinson J, Cantillon M, Reddy DG, et al
    RP5063, a novel, multimodal, serotonin receptor modulator, prevents Sugen 5416-hypoxia-induced pulmonary arterial hypertension in rats.
    Eur J Pharmacol. 2017 May 30. pii: S0014-2999(17)30381.
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  16. SAVIGNANO FA, Crajoinas RO, Pacheco BPM, Campos LCG, et al
    Attenuated diuresis and natriuresis in response to glucagon-like peptide-1 in hypertensive rats are associated with lower expression of the glucagon-like peptide-1 receptor in the renal vasculature.
    Eur J Pharmacol. 2017 May 30. pii: S0014-2999(17)30386.
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    March 2017
  17. BOMFIM GH, Mendez-Lopez I, Fernandez-Morales JC, Padin JF, et al
    Electrophysiological properties and augmented catecholamine release from chromaffin cells of WKY and SHR rats contributing to the hypertension development elicited by chronic EtOH consumption.
    Eur J Pharmacol. 2017 Mar 16. pii: S0014-2999(17)30179.
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    February 2017
  18. CHANG CC, Lee WS, Chuang CL, Hsin IF, et al
    Effects of raloxifene on portal hypertension and hepatic encephalopathy in cirrhotic rats.
    Eur J Pharmacol. 2017 Feb 24. pii: S0014-2999(17)30117.
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  19. YOON JJ, Lee YJ, Han BH, Choi ES, et al
    Protective effect of betulinic acid on early atherosclerosis in diabetic apolipoprotein-E gene knockout mice.
    Eur J Pharmacol. 2017;796:224-232.
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    January 2017
  20. SINGH A, Kumar BS, Alam S, Iqbal H, et al
    Diethyl-4,4'-dihydroxy-8,3'-neolign-7,7'-dien-9,9'-dionate exhibits antihypertensive activity in rats through increase in intracellular cGMP level and blockade of calcium channels.
    Eur J Pharmacol. 2017 Jan 31. pii: S0014-2999(17)30054.
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  21. GUO JM, Zhang L, Niu XC, Shu H, et al
    Involvement of arterial baroreflex and nicotinic acetylcholine receptor alpha7 subunit pathway in the protection of metformin against stroke in stroke-prone spontaneously hypertensive rats.
    Eur J Pharmacol. 2017 Jan 26. pii: S0014-2999(17)30043.
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  22. AL SULEIMANI YM, Al Mahruqi AS
    The endogenous lipid N-arachidonoyl glycine is hypotensive and nitric oxide-cGMP-dependent vasorelaxant.
    Eur J Pharmacol. 2017;794:209-215.
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    December 2016
  23. LIMA-SEOLIN BG, Colombo R, Bonetto JH, Teixeira RB, et al
    Bucindolol improves right ventricle function in rats with pulmonary arterial hypertension through the reversal of autonomic imbalance.
    Eur J Pharmacol. 2016 Dec 20. pii: S0014-2999(16)30809.
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  24. MOSTAFA DK, Nasra RA, Zahran N, Ghoneim MT, et al
    Pleiotropic protective effects of Vitamin D against high fat diet-induced metabolic syndrome in rats: One for all.
    Eur J Pharmacol. 2016;792:38-47.
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    October 2016
  25. FERREIRA RB, de Oliveira MG, Antunes E, Almeida WP, et al
    New 2-Aminothiazoline derivatives lower blood pressure of spontaneously hypertensive rats (SHR) via I1-imidazoline and alpha-2 adrenergic receptors activation.
    Eur J Pharmacol. 2016 Oct 8. pii: S0014-2999(16)30650.
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    September 2016
  26. ALTOAMA K, Mallem MY, Thorin C, Betti E, et al
    Effect of nebivolol treatment during pregnancy on the intrauterine fetal growth, mortality and pup postnatal development in the l-NAME-induced hypertensive rats.
    Eur J Pharmacol. 2016;791:465-472.
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  27. QUINTANA-VILLAMANDOS B, Gonzalez MC, Delgado-Martos MJ, Condezo-Hoyos L, et al
    Short-term esmolol attenuates remodeling of the thoracic aorta in hypertensive rats by decreasing concentrations of ADMA down-regulated by oxidative stress.
    Eur J Pharmacol. 2016;791:502-509.
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    August 2016
  28. LI J, Liang X, Zhou Y, Zhang S, et al
    Role of dynorphin in hypoxic pulmonary hypertension.
    Eur J Pharmacol. 2016 Aug 24. pii: S0014-2999(16)30538.
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  29. COBOS-PUC LE, Sanchez-Lopez A, Centurion D
    Pharmacological analysis of the cardiac sympatho-inhibitory actions of moxonidine and agmatine in pithed spontaneously hypertensive rats.
    Eur J Pharmacol. 2016;791:25-36.
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    July 2016
  30. YOUNIS FM, Blumenthal-Katzir T, Hollander K, Grigoriadis N, et al
    Telmisartan-mediated metabolic profile conferred brain protection in diabetic hypertensive rats as evidenced by magnetic resonance imaging, behavioral studies and histology.
    Eur J Pharmacol. 2016 Jul 11. pii: S0014-2999(16)30451.
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  31. DIBAS A, Yorio T
    Glucocorticoid Therapy and ocular hypertension.
    Eur J Pharmacol. 2016 Jul 4. pii: S0014-2999(16)30376.
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    May 2016
  32. CHRYSSA P, Georgia T, Maria Eleni M, Georgios K, et al
    Furosemide modifies heart hypertrophy and glycosaminoglycan myocardium content in a rat model of neurogenic hypertension.
    Eur J Pharmacol. 2016 May 21. pii: S0014-2999(16)30327.
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  33. YAMAMURA A, Yagi S, Ohara N, Tsukamoto K, et al
    Calcilytics enhance sildenafilinduced antiproliferation in idiopathic pulmonary arterial hypertension.
    Eur J Pharmacol. 2016 May 6. pii: S0014-2999(16)30312.
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    April 2016
  34. UCHII M, Kimoto N, Sakai M, Kitayama T, et al
    Glucose-independent renoprotective mechanisms of the tissue dipeptidyl peptidase-4 inhibitor, saxagliptin, in Dahl salt-sensitive hypertensive rats.
    Eur J Pharmacol. 2016 Apr 7. pii: S0014-2999(16)30209.
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    March 2016
  35. SILAMBARASAN T, Manivannan J, Raja B, Chatterjee S, et al
    Prevention of cardiac dysfunction, kidney fibrosis and lipid metabolic alterations in l-NAME hypertensive rats by sinapic acid-Role of HMG-CoA reductase.
    Eur J Pharmacol. 2016 Mar 2. pii: S0014-2999(16)30116.
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    February 2016
  36. LIU B, Li T, Peng JJ, Zhang JJ, et al
    Non-muscle myosin light chain promotes endothelial progenitor cells senescence and dysfunction in pulmonary hypertensive rats through up-regulation of NADPH oxidase.
    Eur J Pharmacol. 2016 Feb 9. pii: S0014-2999(16)30045.
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    January 2016
  37. KHAMMY MM, Angus JA, Wright CE
    vascular reactivity of rabbit isolated renal and femoral resistance arteries in renal wrap hypertension.
    Eur J Pharmacol. 2016 Jan 21. pii: S0014-2999(16)30003.
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    November 2015
  38. ARAI K, Tsuruoka H, Homma T
    CS-3150, a novel non-steroidal mineralocorticoid receptor antagonist, prevents hypertension and cardiorenal injury in Dahl salt-sensitive hypertensive rats.
    Eur J Pharmacol. 2015 Nov 19. pii: S0014-2999(15)30369.
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  39. QIN X, Hou X, Liang T, Chen L, et al
    Farrerol can attenuate the aortic lesion in spontaneously hypertensive rats via the upregulation of eNOS and reduction of NAD(P)H oxidase activity.
    Eur J Pharmacol. 2015 Nov 18. pii: S0014-2999(15)30362.
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