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Articles published in
Proc Natl Acad Sci U S A
    April 2024
  1. SACCHI P, Wright SE, Neoptolemou P, Lampronti GI, et al
    Crystal size, shape, and conformational changes drive both the disappearance and reappearance of ritonavir polymorphs in the mill.
    Proc Natl Acad Sci U S A. 2024;121:e2319127121.
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  2. BISWAS A, Choudhuri I, Arnold E, Lyumkis D, et al
    Kinetic coevolutionary models predict the temporal emergence of HIV-1 resistance mutations under drug selection pressure.
    Proc Natl Acad Sci U S A. 2024;121:e2316662121.
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    March 2024
  3. SHICHIJO T, Yasunaga JI, Sato K, Nosaka K, et al
    Vulnerability to APOBEC3G linked to the pathogenicity of deltaretroviruses.
    Proc Natl Acad Sci U S A. 2024;121:e2309925121.
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  4. OBRIEN SJ
    Legacy of a magic gene-CCR5-?32: From discovery to clinical benefit in a generation.
    Proc Natl Acad Sci U S A. 2024;121:e2321907121.
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    February 2024
  5. MIRANZADEH MAHABADI H, Lin YCJ, Ogando NS, Moussa EW, et al
    Monkeypox virus infection of human astrocytes causes gasdermin B cleavage and pyroptosis.
    Proc Natl Acad Sci U S A. 2024;121:e2315653121.
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    January 2024
  6. JURASKA M, Bai H, deCamp AC, Magaret CA, et al
    Prevention efficacy of the broadly neutralizing antibody VRC01 depends on HIV-1 envelope sequence features.
    Proc Natl Acad Sci U S A. 2024;121:e2308942121.
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  7. HUDAIT A, Voth GA
    HIV-1 capsid shape, orientation, and entropic elasticity regulate translocation into the nuclear pore complex.
    Proc Natl Acad Sci U S A. 2024;121:e2313737121.
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    December 2023
  8. AIT SAID M, Bejjani F, Abdouni A, Segeral E, et al
    Premature transcription termination complex proteins PCF11 and WDR82 silence HIV-1 expression in latently infected cells.
    Proc Natl Acad Sci U S A. 2023;120:e2313356120.
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    November 2023
  9. TWIZERIMANA AP, Becker D, Zhu S, Luedde T, et al
    The cyclophilin A-binding loop of the capsid regulates the human TRIM5alpha sensitivity of nonpandemic HIV-1.
    Proc Natl Acad Sci U S A. 2023;120:e2306374120.
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    October 2023
  10. KUMAR MR, Fray EJ, Bender AM, Zitzmann C, et al
    Biphasic decay of intact SHIV genomes following initiation of antiretroviral therapy complicates analysis of interventions targeting the reservoir.
    Proc Natl Acad Sci U S A. 2023;120:e2313209120.
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    August 2023

  11. Correction for Highland et al., Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM.
    Proc Natl Acad Sci U S A. 2023;120:e2312510120.
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  12. WANG Z, Petricca J, Liu M, Zhang S, et al
    SETD7 functions as a transcription repressor in prostate cancer via methylating FOXA1.
    Proc Natl Acad Sci U S A. 2023;120:e2220472120.
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    July 2023
  13. ZHANG P, Falcone S, Tsybovsky Y, Singh M, et al
    Increased neutralization potency and breadth elicited by a SARS-CoV-2 mRNA vaccine forming virus-like particles.
    Proc Natl Acad Sci U S A. 2023;120:e2305896120.
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  14. WAHEED AA, Zhu Y, Agostino E, Naing L, et al
    Neutral sphingomyelinase 2 is required for HIV-1 maturation.
    Proc Natl Acad Sci U S A. 2023;120:e2219475120.
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  15. YOO SW, Waheed AA, Deme P, Tohumeken S, et al
    Inhibition of neutral sphingomyelinase 2 impairs HIV-1 envelope formation and substantially delays or eliminates viral rebound.
    Proc Natl Acad Sci U S A. 2023;120:e2219543120.
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    June 2023
  16. CASANOVA JL
    From second thoughts on the germ theory to a full-blown host theory.
    Proc Natl Acad Sci U S A. 2023;120:e2301186120.
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  17. WANG J, Koduru T, Harish B, McCallum SA, et al
    Pressure pushes tRNA(Lys3) into excited conformational states.
    Proc Natl Acad Sci U S A. 2023;120:e2215556120.
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  18. MOTTA FC, McGoff K, Moseley RC, Cho CY, et al
    The parasite intraerythrocytic cycle and human circadian cycle are coupled during malaria infection.
    Proc Natl Acad Sci U S A. 2023;120:e2216522120.
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  19. MISSON MINDREBO L, Liu H, Ozorowski G, Tran Q, et al
    Fully synthetic platform to rapidly generate tetravalent bispecific nanobody-based immunoglobulins.
    Proc Natl Acad Sci U S A. 2023;120:e2216612120.
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  20. GUENTHOER J, Lilly M, Starr TN, Dadonaite B, et al
    Identification of broad, potent antibodies to functionally constrained regions of SARS-CoV-2 spike following a breakthrough infection.
    Proc Natl Acad Sci U S A. 2023;120:e2220948120.
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  21. NIKOLAITCHIK OA, Islam S, Kitzrow JP, Duchon A, et al
    HIV-1 usurps transcription start site heterogeneity of host RNA polymerase II to maximize replication fitness.
    Proc Natl Acad Sci U S A. 2023;120:e2305103120.
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  22. TADA T, Minnee J, Landau NR
    Vectored immunoprophylaxis and treatment of SARS-CoV-2 infection in a preclinical model.
    Proc Natl Acad Sci U S A. 2023;120:e2303509120.
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    May 2023
  23. MARIOTTON J, Cohen E, Zhu A, Auffray C, et al
    TRPV1 activation in human Langerhans cells and T cells inhibits mucosal HIV-1 infection via CGRP-dependent and independent mechanisms.
    Proc Natl Acad Sci U S A. 2023;120:e2302509120.
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  24. GOLDBERG BS, Spencer DA, Pandey S, Ordonez T, et al
    Complement contributes to antibody-mediated protection against repeated SHIV challenge.
    Proc Natl Acad Sci U S A. 2023;120:e2221247120.
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  25. JUDITH D, Versapuech M, Bejjani F, Palaric M, et al
    ATG5 selectively engages virus-tethered BST2/tetherin in an LC3C-associated pathway.
    Proc Natl Acad Sci U S A. 2023;120:e2217451120.
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  26. DASH PK, Chen C, Kaminski R, Su H, et al
    CRISPR editing of CCR5 and HIV-1 facilitates viral elimination in antiretroviral drug-suppressed virus-infected humanized mice.
    Proc Natl Acad Sci U S A. 2023;120:e2217887120.
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  27. HIGHLAND CM, Tan A, Ricana CL, Briggs JAG, et al
    Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM.
    Proc Natl Acad Sci U S A. 2023;120:e2220545120.
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    April 2023
  28. STACEY JCV, Tan A, Lu JM, James LC, et al
    Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.
    Proc Natl Acad Sci U S A. 2023;120:e2220557120.
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    March 2023
  29. FRITSCHI CJ, Anang S, Gong Z, Mohammadi M, et al
    Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity.
    Proc Natl Acad Sci U S A. 2023;120:e2222073120.
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  30. SHEN Q, Kumari S, Xu C, Jang S, et al
    The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores.
    Proc Natl Acad Sci U S A. 2023;120:e2202815120.
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  31. WANG JYJ, Khmelinskaia A, Sheffler W, Miranda MC, et al
    Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains.
    Proc Natl Acad Sci U S A. 2023;120:e2214556120.
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  32. CHAU S, Gao J, Diao AJ, Cao SB, et al
    Diverse yeast antiviral systems prevent lethal pathogenesis caused by the L-A mycovirus.
    Proc Natl Acad Sci U S A. 2023;120:e2208695120.
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  33. ETEMAD B, Sun X, Li Y, Melberg M, et al
    HIV post-treatment controllers have distinct immunological and virological features.
    Proc Natl Acad Sci U S A. 2023;120:e2218960120.
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    February 2023
  34. BELL BN, Bruun TUJ, Friedland N, Kim PS, et al
    HIV-1 prehairpin intermediate inhibitors show efficacy independent of neutralization tier.
    Proc Natl Acad Sci U S A. 2023;120:e2215792120.
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  35. PANDEY A, Wells CR, Stadnytskyi V, Moghadas SM, et al
    Disease burden among Ukrainians forcibly displaced by the 2022 Russian invasion.
    Proc Natl Acad Sci U S A. 2023;120:e2215424120.
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  36. TAGAWA T, Oh D, Dremel S, Mahesh G, et al
    A virus-induced circular RNA maintains latent infection of Kaposi's sarcoma herpesvirus.
    Proc Natl Acad Sci U S A. 2023;120:e2212864120.
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    January 2023
  37. PANG H, Ouyang J, Yang Z, Shang H, et al
    Urokinase plasminogen activator surface receptor restricts HIV-1 replication by blocking virion release from the cell membrane.
    Proc Natl Acad Sci U S A. 2023;120:e2212991120.
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  38. LAGA I, Niu X, Rucinski K, Baral S, et al
    Mapping the number of female sex workers in countries across sub-Saharan Africa.
    Proc Natl Acad Sci U S A. 2023;120:e2200633120.
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  39. LUO S, Jing C, Ye AY, Kratochvil S, et al
    Humanized V(D)J-rearranging and TdT-expressing mouse vaccine models with physiological HIV-1 broadly neutralizing antibody precursors.
    Proc Natl Acad Sci U S A. 2023;120:e2217883120.
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  40. LI C, Mori LP, Lyu S, Bronson R, et al
    The chaperone protein p32 stabilizes HIV-1 Tat and strengthens the p-TEFb/RNAPII/TAR complex promoting HIV transcription elongation.
    Proc Natl Acad Sci U S A. 2023;120:e2217476120.
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    December 2022
  41. WU S, Li H, Ma A
    Exact reaction coordinates for flap opening in HIV-1 protease.
    Proc Natl Acad Sci U S A. 2022;119:e2214906119.
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    November 2022
  42. SUZUKI K, Zaunders J, Gates TM, Levert A, et al
    Elevation of cell-associated HIV-1 transcripts in CSF CD4+ T cells, despite effective antiretroviral therapy, is linked to brain injury.
    Proc Natl Acad Sci U S A. 2022;119:e2210584119.
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    October 2022
  43. SONG Y, Nguyen XN, Kumar A, da Silva C, et al
    Trim69 is a microtubule regulator that acts as a pantropic viral inhibitor.
    Proc Natl Acad Sci U S A. 2022;119:e2211467119.
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    September 2022
  44. VILLABONA-ARENAS CJ, Hue S, Baxter JAC, Hall M, et al
    Using phylogenetics to infer HIV-1 transmission direction between known transmission pairs.
    Proc Natl Acad Sci U S A. 2022;119:e2210604119.
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  45. LUTZ EA, Agarwal Y, Momin N, Cowles SC, et al
    Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies.
    Proc Natl Acad Sci U S A. 2022;119:e2205983119.
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    August 2022
  46. VELU V, Titanji K, Ahmed H, Shetty RD, et al
    PD-1 blockade following ART interruption enhances control of pathogenic SIV in rhesus macaques.
    Proc Natl Acad Sci U S A. 2022;119:e2202148119.
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  47. LY PT, Xu S, Wirawan M, Luo D, et al
    ZAP isoforms regulate unfolded protein response and epithelial- mesenchymal transition.
    Proc Natl Acad Sci U S A. 2022;119:e2121453119.
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    July 2022
  48. SINGH AK, De Wijngaert B, Bijnens M, Uyttersprot K, et al
    Cryo-EM structures of wild-type and E138K/M184I mutant HIV-1 RT/DNA complexed with inhibitors doravirine and rilpivirine.
    Proc Natl Acad Sci U S A. 2022;119:e2203660119.
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  49. YUAN M, Zhu X, He WT, Zhou P, et al
    A broad and potent neutralization epitope in SARS-related coronaviruses.
    Proc Natl Acad Sci U S A. 2022;119:e2205784119.
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  50. WALKER-SPERLING V, Digitale JC, Viard M, Martin MP, et al
    Genetic variation that determines TAPBP expression levels associates with the course of malaria in an HLA allotype-dependent manner.
    Proc Natl Acad Sci U S A. 2022;119:e2205498119.
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  51. CADA AK, Pavlin MR, Castillo JP, Tong AB, et al
    Friction-driven membrane scission by the human ESCRT-III proteins CHMP1B and IST1.
    Proc Natl Acad Sci U S A. 2022;119:e2204536119.
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  52. BALDWIN ET, Gotte M, Tchesnokov EP, Arnold E, et al
    Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for HERV-K-specific inhibition.
    Proc Natl Acad Sci U S A. 2022;119:e2200260119.
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  53. CACCURI F, Messali S, Zani A, Campisi G, et al
    HIV-1 mutants expressing B cell clonogenic matrix protein p17 variants are increasing their prevalence worldwide.
    Proc Natl Acad Sci U S A. 2022;119:e2122050119.
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    June 2022
  54. SAMAL AB, Green TJ, Saad JS
    Atomic view of the HIV-1 matrix lattice; implications on virus assembly and envelope incorporation.
    Proc Natl Acad Sci U S A. 2022;119:e2200794119.
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    May 2022
  55. HORVATH S, Lu AT, Haghani A, Zoller JA, et al
    DNA methylation clocks for dogs and humans.
    Proc Natl Acad Sci U S A. 2022;119:e2120887119.
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  56. MANRY J, Bastard P, Gervais A, Le Voyer T, et al
    The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies.
    Proc Natl Acad Sci U S A. 2022;119:e2200413119.
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  57. TIAN JB, Yang J, Joslin WC, Flockerzi V, et al
    TRPC4 and GIRK channels underlie neuronal coding of firing patterns that reflect Gq/11-Gi/o coincidence signals of variable strengths.
    Proc Natl Acad Sci U S A. 2022;119:e2120870119.
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  58. TAURA M, Frank JA, Takahashi T, Kong Y, et al
    APOBEC3A regulates transcription from interferon-stimulated response elements.
    Proc Natl Acad Sci U S A. 2022;119:e2011665119.
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  59. OLABODE AS, Ng GT, Wade KE, Salnikov M, et al
    Revisiting the recombinant history of HIV-1 group M with dynamic network community detection.
    Proc Natl Acad Sci U S A. 2022;119:e2108815119.
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  60. KAVAKLI KC, Rotondi V
    US foreign aid restrictions and maternal and children's health: Evidence from the "Mexico City Policy".
    Proc Natl Acad Sci U S A. 2022;119:e2123177119.
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    April 2022

  61. Correction for Lu et al., Screening for gene expression fluctuations reveals latency-promoting agents of HIV.
    Proc Natl Acad Sci U S A. 2022;119:e2203398119.
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  62. SENGUPTA S, Board NL, Wu F, Moskovljevic M, et al
    TCR-mimic bispecific antibodies to target the HIV-1 reservoir.
    Proc Natl Acad Sci U S A. 2022;119:e2123406119.
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    March 2022
  63. YU A, Lee EMY, Briggs JAG, Ganser-Pornillos BK, et al
    Strain and rupture of HIV-1 capsids during uncoating.
    Proc Natl Acad Sci U S A. 2022;119:e2117781119.
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  64. ZEBERG H
    The major genetic risk factor for severe COVID-19 is associated with protection against HIV.
    Proc Natl Acad Sci U S A. 2022;119.
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    February 2022
  65. LIU H, Zheng ZM
    Linking a nuclear lncRNA to cytoplasmic lysosome integrity and cell death.
    Proc Natl Acad Sci U S A. 2022;119.
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  66. SWAN DA, Rolland M, Herbeck JT, Schiffer JT, et al
    Evolution during primary HIV infection does not require adaptive immune selection.
    Proc Natl Acad Sci U S A. 2022;119.
    >> Share

  67. WHITE JA, Simonetti FR, Beg S, McMyn NF, et al
    Complex decay dynamics of HIV virions, intact and defective proviruses, and 2LTR circles following initiation of antiretroviral therapy.
    Proc Natl Acad Sci U S A. 2022;119.
    >> Share

  68. NIGHTINGALE K, Potts M, Hunter LM, Fielding CA, et al
    Human cytomegalovirus protein RL1 degrades the antiviral factor SLFN11 via recruitment of the CRL4 E3 ubiquitin ligase complex.
    Proc Natl Acad Sci U S A. 2022;119.
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    January 2022
  69. YANG B, Jia Y, Meng Y, Xue Y, et al
    SNX27 suppresses SARS-CoV-2 infection by inhibiting viral lysosome/late endosome entry.
    Proc Natl Acad Sci U S A. 2022;119.
    >> Share

  70. CHO A, Gaebler C, Olveira T, Ramos V, et al
    Longitudinal clonal dynamics of HIV-1 latent reservoirs measured by combination quadruplex polymerase chain reaction and sequencing.
    Proc Natl Acad Sci U S A. 2022;119.
    >> Share

  71. GEIS FK, Sabo Y, Chen X, Li Y, et al
    CHAF1A/B mediate silencing of unintegrated HIV-1 DNAs early in infection.
    Proc Natl Acad Sci U S A. 2022;119.
    >> Share

  72. RUJAS E, Cui H, Burnie J, Aschner CB, et al
    Engineering pan-HIV-1 neutralization potency through multispecific antibody avidity.
    Proc Natl Acad Sci U S A. 2022;119.
    >> Share

  73. WANG S, Zhao L, Zhang X, Zhang J, et al
    Neuropilin-1, a myeloid cell-specific protein, is an inhibitor of HIV-1 infectivity.
    Proc Natl Acad Sci U S A. 2022;119.
    >> Share

  74. SINGH G, Seufzer B, Song Z, Zucko D, et al
    HIV-1 hypermethylated guanosine cap licenses specialized translation unaffected by mTOR.
    Proc Natl Acad Sci U S A. 2022;119.
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  75. Correction for Shanmugapriya et al., Dynactin 1 negatively regulates HIV-1 infection by sequestering the host cofactor CLIP170.
    Proc Natl Acad Sci U S A. 2022;119.
    >> Share

    December 2021
  76. NIKOLAITCHIK OA, Liu S, Kitzrow JP, Liu Y, et al
    Selective packaging of HIV-1 RNA genome is guided by the stability of 5' untranslated region polyA stem.
    Proc Natl Acad Sci U S A. 2021;118.
    >> Share

    November 2021
  77. WICHE SALINAS TR, Zhang Y, Sarnello D, Zhyvoloup A, et al
    Th17 cell master transcription factor RORC2 regulates HIV-1 gene expression and viral outgrowth.
    Proc Natl Acad Sci U S A. 2021;118.
    >> Share

  78. SHEVCHENKO AK, Zhernakova DV, Malov SV, Komissarov A, et al
    Genome-wide association study reveals genetic variants associated with HIV-1C infection in a Botswana study population.
    Proc Natl Acad Sci U S A. 2021;118.
    >> Share

  79. PAQUIN-PROULX D, Lal KG, Phuang-Ngern Y, Creegan M, et al
    Preferential and persistent impact of acute HIV-1 infection on CD4(+) iNKT cells in colonic mucosa.
    Proc Natl Acad Sci U S A. 2021;118.
    >> Share

  80. LEVY R, Zhang P, Bastard P, Dorgham K, et al
    Monoclonal antibody-mediated neutralization of SARS-CoV-2 in an IRF9-deficient child.
    Proc Natl Acad Sci U S A. 2021;118.
    >> Share

  81. ZHANG L, Richards A, Barrasa MI, Hughes SH, et al
    Reply to Briggs et al.: Genomic integration and expression of SARS-CoV-2 sequences can explain prolonged or recurrent viral RNA detection.
    Proc Natl Acad Sci U S A. 2021;118.
    >> Share

    October 2021
  82. SHANMUGAPRIYA S, Santos da Silva E, Campbell JA, Boisjoli MP, et al
    Dynactin 1 negatively regulates HIV-1 infection by sequestering the host cofactor CLIP170.
    Proc Natl Acad Sci U S A. 2021;118.
    >> Share

  83. RAK R, Polonsky M, Eizenberg-Magar I, Mo Y, et al
    Dynamic changes in tRNA modifications and abundance during T cell activation.
    Proc Natl Acad Sci U S A. 2021;118.
    >> Share

  84. LEVIN JG, Rein A
    Show your cap or be packaged into HIV-1.
    Proc Natl Acad Sci U S A. 2021;118.
    >> Share

  85. SCHWANDT H, Currie J, Bar M, Banks J, et al
    Inequality in mortality between Black and White Americans by age, place, and cause and in comparison to Europe, 1990 to 2018.
    Proc Natl Acad Sci U S A. 2021;118.
    >> Share

    August 2021
  86. HARDCASTLE M
    QnAs with Joel N. Blankson.
    Proc Natl Acad Sci U S A. 2021;118.
    >> Share


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