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Articles published in
Antimicrob Agents Chemother
    September 2017
  1. PATEL S, Leibrand CR, Palasuberniam P, Couraud PO, et al
    Effects of HIV-1 Tat and Methamphetamine on Blood-Brain Barrier Integrity and Function In Vitro.
    Antimicrob Agents Chemother. 2017 Sep 11. pii: AAC.01307.
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  2. ZHAO N, Wang G, Das AT, Berkhout B, et al
    Combinatorial CRISPR-Cas9 and RNAi attack on HIV-1 DNA and RNA can lead to cross-resistance.
    Antimicrob Agents Chemother. 2017 Sep 11. pii: AAC.01486.
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  3. KOSAKA M, Ushiki A, Ikuyama Y, Hirai K, et al
    Efficacy and toxicity of low-dose trimethoprim-sulfamethoxazole for the treatment of pneumocystis pneumonia in patients without human immunodeficiency virus infection: A four-center retrospective study.
    Antimicrob Agents Chemother. 2017 Sep 11. pii: AAC.01173.
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  4. GARCIA-VIDAL E, Castellvi M, Pujantell M, Badia R, et al
    Evaluation of the innate immune modulator acitretin as a strategy to clear the HIV reservoir.
    Antimicrob Agents Chemother. 2017 Sep 5. pii: AAC.01368.
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    August 2017
  5. CHATTERJEE SS, Chen L, Gilbert A, da Costa TM, et al
    PBP4 mediates beta-lactam resistance by altered function.
    Antimicrob Agents Chemother. 2017 Aug 14. pii: AAC.00932.
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  6. MCBRIDE JW, Dias N, Cameron D, Offord RE, et al
    Pharmacokinetics of the protein microbicide 5P12-RANTES in sheep following single dose vaginal gel administration.
    Antimicrob Agents Chemother. 2017 Aug 7. pii: AAC.00965.
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    July 2017
  7. KIRBY KA, Myshakina NA, Christen MT, Chen YL, et al
    A 2-hydroxyisoquinoline-1,3-dione active site RNase H inhibitor binds in multiple modes to HIV-1 reverse transcriptase.
    Antimicrob Agents Chemother. 2017 Jul 31. pii: AAC.01351.
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  8. FORD SL, Sutton K, Lou Y, Zhang Z, et al
    Effect of Rifampin on the Single-Dose Pharmacokinetics of Oral Cabotegravir in Healthy Subjects.
    Antimicrob Agents Chemother. 2017 Jul 24. pii: AAC.00487.
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  9. REZNICEK J, Ceckova M, Ptackova Z, Martinec O, et al
    MDR1 and BCRP transporter-mediated drug-drug interaction between rilpivirine and abacavir; effect on intestinal absorption.
    Antimicrob Agents Chemother. 2017 Jul 10. pii: AAC.00837.
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    June 2017
  10. CHAN CN, Trinite B, Levy DN
    Potent inhibition of HIV-1 replication in resting CD4 T cells by resveratrol and pterostilbene.
    Antimicrob Agents Chemother. 2017 Jun 26. pii: AAC.00408.
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  11. CHIREHWA MT, McIlleron H, Rustomjee R, Mthiyane T, et al
    Pharmacokinetics of Pyrazinamide: optimising dosing regimens for drug-sensitive and -resistant tuberculosis.
    Antimicrob Agents Chemother. 2017 Jun 12. pii: AAC.00490.
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  12. WENSEL D, Sun Y, Li Z, Zhang S, et al
    Discovery and Characterization of a Novel CD4-Binding Adnectin with Potent Anti-HIV Activity.
    Antimicrob Agents Chemother. 2017 Jun 5. pii: AAC.00508.
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  13. FOLI Y, Ghebremichael M, Li M, Paintsil E, et al
    Upregulation of Apoptosis Pathway Genes in Peripheral Blood Mononuclear Cells of HIV-Infected Individuals with Antiretroviral Therapy-Associated Mitochondrial Toxicity.
    Antimicrob Agents Chemother. 2017 Jun 5. pii: AAC.00522.
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    May 2017
  14. HABTEWOLD A, Aklillu E, Makonnen E, Yimer G, et al
    Population pharmacokinetic model linking plasma and peripheral blood mononuclear cells (PBMCs) concentrations of efavirenz and its metabolite, 8-hydroxy-efavirenz in HIV patients.
    Antimicrob Agents Chemother. 2017 May 30. pii: AAC.00207.
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  15. ROSADO-SANCHEZ I, Herrero-Fernandez I, Alvarez-Rios AI, Genebat M, et al
    A lower baseline CD4/CD8 T-cell ratio is independently associated with immunodiscordant response to antiretroviral therapy in HIV-infected subjects.
    Antimicrob Agents Chemother. 2017 May 30. pii: AAC.00605.
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  16. WU VH, Smith RA, Masoum S, Raugi DN, et al
    MK-8591 (4' -ethynyl-2-fluoro-2' -deoxyadenosine) exhibits potent activity against HIV-2 isolates and drug-resistant HIV-2 mutants in culture.
    Antimicrob Agents Chemother. 2017 May 30. pii: AAC.00744.
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  17. FLETA-SORIANO E, Smutna K, Martinez JP, Lorca Oro C, et al
    The myxobacterial metabolite Soraphen A inhibits HIV-1 by reducing virus production and altering virion composition.
    Antimicrob Agents Chemother. 2017 May 22. pii: AAC.00739.
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  18. HACHIYA A, Kirby KA, Ido Y, Shigemi U, et al
    Impact of HIV-1 Integrase L74F/V75I Mutations from a Clinical Isolate on Resistance to Second-Generation Integrase Strand Transfer Inhibitors.
    Antimicrob Agents Chemother. 2017 May 22. pii: AAC.00315.
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  19. STEENS JM, Scherrer D, Gineste P, Barrett PN, et al
    Safety, Pharmacokinetics and_Antiviral Activity of a Novel HIV Antiviral, ABX464, in Treatment- Naive HIV Infected Subjects: a Phase II Randomized, Controlled Study.
    Antimicrob Agents Chemother. 2017 May 15. pii: AAC.00545.
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  20. GIACOBBI NS, Sluis-Cremer N
    In Vitro Cross-Resistance Profiles of Rilpivirine, Dapivirine and MIV-150: NNRTI Microbicides in Clinical Development for the Prevention of HIV-1 Infection.
    Antimicrob Agents Chemother. 2017 May 15. pii: AAC.00277.
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  21. PRESSIAT C, Amorissani-Folquet M, Yonaba C, Treluyer JM, et al
    Pharmacokinetics of Efavirenz in 2-3 years old children: a high dose of 25 mg/kg per day.
    Antimicrob Agents Chemother. 2017 May 8. pii: AAC.00297.
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    April 2017
  22. ZHANG Y, Clarke W, Marzinke MA, Piwowar-Manning E, et al
    Evaluation of a multi-drug assay for monitoring adherence to a regimen for HIV pre-exposure prophylaxis in a clinical study (HIV Prevention Trials Network 073).
    Antimicrob Agents Chemother. 2017 Apr 24. pii: AAC.02743.
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  23. NAKAMURA RL, Burlingame MA, Yang S, Crosby DC, et al
    Identification and optimization of thienopyridine carboxamides as inhibitors of HIV regulatory complexes.
    Antimicrob Agents Chemother. 2017 Apr 17. pii: AAC.02366.
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  24. ZHAO C, Gunawardana M, Villinger F, Baum MM, et al
    Pharmacokinetics and Preliminary Safety of Pod-Intravaginal Rings Delivering the Monoclonal Antibody VRC01-N for HIV Prophylaxis in a Macaque Model.
    Antimicrob Agents Chemother. 2017 Apr 17. pii: AAC.02465.
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  25. DAS K, Martinez SE, Arnold E
    Structural Insights into HIV Reverse Transcriptase Mutations Q151M and Q151M Complex that Confer Multi-Nucleoside Drug Resistance.
    Antimicrob Agents Chemother. 2017 Apr 10. pii: AAC.00224.
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    March 2017
  26. RIMAWI BH, Johnson E, Rajakumar A, Tao S, et al
    Pharmacokinetics and Placental Transfer of Elvitegravir and Dolutegravir, and Other Antiretrovirals during Pregnancy.
    Antimicrob Agents Chemother. 2017 Mar 27. pii: AAC.02213.
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  27. HUBER AD, Michailidis E, Tang J, Puray-Chavez MN, et al
    3-hydroxypyrimidine-2,4-diones as novel hepatitis B virus antivirals targeting the viral ribonuclease H.
    Antimicrob Agents Chemother. 2017 Mar 20. pii: AAC.00245.
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  28. MOYA B, Barcelo IM, Bhagwat S, Patel M, et al
    WCK 5107 (Zidebactam) & WCK 5153: Novel inhibitors of PBP2 showing potent "beta-lactam enhancer" activity against Pseudomonas aeruginosa, including multidrug-resistant metallo-beta-lactamase-producing high-risk clones.
    Antimicrob Agents Chemother. 2017 Mar 13. pii: AAC.02529.
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  29. NIGO M, Diaz L, Carvajal LP, Tran TT, et al
    Ceftaroline-Resistant, Daptomycin-Tolerant, and Heterogeneous Vancomycin-Intermediate Methicillin-Resistant Staphylococcus aureus Causing Infective Endocarditis.
    Antimicrob Agents Chemother. 2017;61.
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    February 2017
  30. VIDYAPRAKASH E, Abrams AJ, Shafer WM, Trees DL, et al
    Whole genome sequencing of a large panel of contemporary Neisseria gonorrhoeae clinical isolates indicates that a wild-type mtrA gene is common: implications for inducible antimicrobial resistance.
    Antimicrob Agents Chemother. 2017 Feb 13. pii: AAC.00262.
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  31. KOUTSOUDAKIS G, Paris de Leon A, Herrera C, Dorner M, et al
    Oligonucleotide-lipid conjugates forming G-quadruplex structures are potent and pangenotypic hepatitis C virus entry inhibitors in vitro and ex vivo.
    Antimicrob Agents Chemother. 2017 Feb 13. pii: AAC.02354.
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  32. ROBERTS O, Khoo S, Owen A, Siccardi M, et al
    Interaction of Rifampicin and Darunavir/Ritonavir or Darunavir/Cobicistat In Vitro.
    Antimicrob Agents Chemother. 2017 Feb 13. pii: AAC.01776.
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  33. CHOI SR, Britigan BE, Narayanasamy P
    Ga(III) Nanoparticles Inhibit Growth of Both TB and HIV and Release of IL-6 and IL-8 in Co-Infected Macrophages.
    Antimicrob Agents Chemother. 2017 Feb 6. pii: AAC.02505.
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    January 2017
  34. LE VT, Le HN, Pinheiro MG, Hahn KJ, et al
    Effects of tedizolid phosphate on survival outcomes and suppression of production of staphylococcal toxins in a rabbit model of MRSA necrotizing pneumonia.
    Antimicrob Agents Chemother. 2017 Jan 30. pii: AAC.02734.
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  35. DIEP BA, Hillard JJ, Le VT, Tkaczyk C, et al
    Targeting Alpha Toxin to Mitigate Its Lethal Toxicity in Ferret and Rabbit Models of Staphylococcus aureus Necrotizing Pneumonia.
    Antimicrob Agents Chemother. 2017 Jan 23. pii: AAC.02456.
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  36. GOMARASCA M, Martins TF, Greune L, Hardwidge PR, et al
    Bacterial-derived cell-penetrating peptides deliver gentamicin to kill intracellular pathogens.
    Antimicrob Agents Chemother. 2017 Jan 17. pii: AAC.02545.
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    December 2016
  37. GROSSMAN NT, Casadevall A
    Physiological Differences in C. neoformans in vitro versus in vivo and Their Effects on Antifungal Susceptibility.
    Antimicrob Agents Chemother. 2016 Dec 28. pii: AAC.02108.
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  38. ZERBATO JM, Tachedjian G, Sluis-Cremer N
    Nonnucleoside Reverse Transcriptase Inhibitors Reduce HIV-1 Virus Production from Latently Infected Resting CD4+ T Cells Following Latency Reversal.
    Antimicrob Agents Chemother. 2016 Dec 19. pii: AAC.01736.
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  39. LOMONOSOVA E, Zlotnick A, Tavis JE
    Synergistic Interactions between Hepatitis B Virus Ribonuclease H Antagonists and Other Inhibitors.
    Antimicrob Agents Chemother. 2016 Dec 12. pii: AAC.02441.
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  40. FOFANA MO, Shrestha S, Knight GM, Cohen T, et al
    Role of pyrazinamide in the emergence of extensively drug-resistant tuberculosis: a multi-strain mathematical model.
    Antimicrob Agents Chemother. 2016 Dec 12. pii: AAC.00498.
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  41. VALADE E, Bouazza N, Lui G, Martinez Illamola S, et al
    Population Pharmacokinetic Modeling of Tenofovir in the Male Genital Tract of HIV-infected Patients.
    Antimicrob Agents Chemother. 2016 Dec 12. pii: AAC.02062.
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  42. KING JR, Khatri A, Trinh R, Viani RM, et al
    Pharmacokinetic Evaluation of Darunavir Administered Once or Twice daily in Combination with Ritonavir or the Three Direct Acting Antiviral Regimen of Ombitasvir, Paritaprevir, Ritonavir and Dasabuvir in Adults Co-infected with Hepatitis C and Human I
    Antimicrob Agents Chemother. 2016 Dec 5. pii: AAC.02135.
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    November 2016
  43. FOISSAC F, Blume J, Treluyer JM, Tylleskar T, et al
    Are Prophylactic and Therapeutic Target Concentrations Different? The Case of Lopinavir/ritonavir or Lamivudine Administered to Infants for the Prevention of Mother-to-Child HIV-1 Transmission during Breastfeeding.
    Antimicrob Agents Chemother. 2016 Nov 28. pii: AAC.01869.
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  44. PENROSE KJ, Wallis CL, Brumme CJ, Hamanishi KA, et al
    Frequent Cross-Resistance to Dapivirine in HIV-1 Subtype C-Infected Individuals on Failing First-Line Antiretroviral Therapy in South Africa.
    Antimicrob Agents Chemother. 2016 Nov 28. pii: AAC.01805.
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  45. KHALILIEH S, Yee KL, Sanchez RI, Triantafyllou I, et al
    Results of a doravirine-atorvastatin drug-drug interaction study.
    Antimicrob Agents Chemother. 2016 Nov 21. pii: AAC.01364.
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  46. YEE KL, Sanchez RI, Auger P, Liu R, et al
    An Evaluation of Doravirine Pharmacokinetics When Switching From Efavirenz to Doravirine in Healthy Subjects.
    Antimicrob Agents Chemother. 2016 Nov 21. pii: AAC.01757.
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  47. PONCE CA, Chabe M, George C, Cardenas A, et al
    High prevalence of Pneumocystis jirovecii dihydropteroate synthase gene mutations in patients with first episode of Pneumocystis pneumonia in Santiago, Chile, and their clinical response to trimethoprim-sulfamethoxazole therapy.
    Antimicrob Agents Chemother. 2016 Nov 14. pii: AAC.01290.
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  48. ANTWI S, Yang H, Enimil A, Sarfo AM, et al
    Pharmacokinetics of the First-line Antituberculosis Drugs in Ghanaian Children with Tuberculosis with and without HIV Coinfection.
    Antimicrob Agents Chemother. 2016 Nov 14. pii: AAC.01701.
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  49. MANDAL S, Belshan M, Holec A, Zhou Y, et al
    An enhanced Emtricitabine loaded long-acting nano-formulation for prevention or treatment of HIV infection.
    Antimicrob Agents Chemother. 2016 Nov 7. pii: AAC.01475.
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  50. SONOIKI E, Nsanzabana C, Legac J, Sindhe KM, et al
    Altered Plasmodium falciparum sensitivity to the antiretroviral protease inhibitor lopinavir associated with polymorphisms in pfmdr1.
    Antimicrob Agents Chemother. 2016 Nov 7. pii: AAC.01949.
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    October 2016
  51. BAM RA, Hansen D, Irrinki A, Mulato A, et al
    TLR7 Agonist GS-9620 Is a Potent Inhibitor of Acute HIV-1 Infection in Human Peripheral Blood Mononuclear Cells.
    Antimicrob Agents Chemother. 2016 Oct 31. pii: AAC.01369.
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  52. AOURI M, Barcelo C, Guidi M, Rotger M, et al
    Population pharmacokinetics and pharmacogenetics analysis of Rilpivirine in HIV-1 infected individuals.
    Antimicrob Agents Chemother. 2016 Oct 31. pii: AAC.00899.
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  53. ROBARGE JD, Metzger IF, Lu J, Thong N, et al
    Population pharmacokinetic modeling to estimate the contribution of genetic and non-genetic factors of efavirenz disposition.
    Antimicrob Agents Chemother. 2016 Oct 31. pii: AAC.01813.
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  54. SCHERRER D, Rouzier R, Cardona M, Barrett PN, et al
    Food effect on pharmacokinetic parameters of ABX464 administered orally: a randomized trial in healthy male subjects.
    Antimicrob Agents Chemother. 2016 Oct 31. pii: AAC.01288.
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    September 2016
  55. TSIANG M, Jones GS, Goldsmith J, Mulato A, et al
    Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile.
    Antimicrob Agents Chemother. 2016 Sep 19. pii: AAC.01474.
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  56. FENAUX M, Lin X, Yokokawa F, Sweeney Z, et al
    Anti-viral nucleotide incorporation by recombinant human mitochondrial RNA polymerase is predictive for increased in vivo mitochondrial toxicity risk.
    Antimicrob Agents Chemother. 2016 Sep 19. pii: AAC.01253.
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  57. AMANO M, Salcedo-Gomez PM, Zhao R, Yedidi RS, et al
    A Modified P1 Moiety Enhances in vitro Antiviral Activity against Various Multi-Drug-Resistant HIV-1 Variants and in vitro CNS Penetration Properties of a Novel Nonpeptidic Protease Inhibitor, GRL-10413.
    Antimicrob Agents Chemother. 2016 Sep 12. pii: AAC.01428.
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  58. DESTA Z, Metzger IF, Thong N, Lu JB, et al
    Inhibition of CYP2B6 Activity by Voriconazole Profiled Using Efavirenz Disposition in Healthy Volunteers.
    Antimicrob Agents Chemother. 2016 Sep 6. pii: AAC.01000.
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    August 2016
  59. CASTILLO-MANCILLA J, Seifert S, Campbell K, Coleman S, et al
    Emtricitabine-Triphosphate in Dried Blood Spots as a Marker of Recent Dosing.
    Antimicrob Agents Chemother. 2016 Aug 29. pii: AAC.01017.
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  60. GROOMS TN, Vuong HR, Tyo KM, Malik DA, et al
    Griffithsin-Modified Electrospun Fibers as a Delivery Scaffold to Prevent HIV Infection.
    Antimicrob Agents Chemother. 2016 Aug 22. pii: AAC.00956.
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  61. DIEP BA, Le VT, Visram ZC, Rouha H, et al
    Improved protection in a rabbit model of CA-MRSA necrotizing pneumonia upon neutralization of leukocidins in addition to alpha-hemolysin.
    Antimicrob Agents Chemother. 2016 Aug 15. pii: AAC.01213.
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  62. KHATRI A, Trinh R, Zhao W, Podsadecki T, et al
    Drug-Drug Interaction Between the Direct-acting Antiviral Regimen of Ombitasvir/Paritaprevir/Ritonavir Plus Dasabuvir and the HIV Antiretroviral Agents Dolutegravir or Abacavir Plus Lamivudine.
    Antimicrob Agents Chemother. 2016 Aug 8. pii: AAC.00795.
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  63. ROCKWOOD NN, Meintjes G, Chirehwa M, Wiesner L, et al
    HIV-1 co-infection does not reduce exposure to rifampicin, isoniazid, and pyrazinamide in South African tuberculosis outpatients.
    Antimicrob Agents Chemother. 2016 Aug 1. pii: AAC.00480.
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  64. GONZALEZ-SERNA A, Genebat M, De Luna-Romero M, Tarancon-Diez L, et al
    Validation of the HIV Tropism Test TROCAI Using the Virological Response to a Short-term Maraviroc Monotherapy Exposure.
    Antimicrob Agents Chemother. 2016 Aug 1. pii: AAC.01326.
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    July 2016
  65. MARTINEZ ZS, Castro E, Seong CS, Ceron MR, et al
    Fullerene Derivatives Strongly Inhibit HIV-1 Replication by Affecting Virus Maturation without Impairing Protease Activity.
    Antimicrob Agents Chemother. 2016 Jul 18. pii: AAC.00341.
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  66. LE VT, Tkaczyk C, Chau S, Rao RL, et al
    Acute bacterial skin and skin structure infection: Critical role of alpha-toxin and protective effects of its neutralization by a human antibody.
    Antimicrob Agents Chemother. 2016 Jul 11. pii: AAC.00710.
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  67. CECKOVA M, Reznicek J, Ptackova Z, Cerveny L, et al
    Interaction of lamivudine with ABC and SLC transporters: role in placental transport.
    Antimicrob Agents Chemother. 2016 Jul 11. pii: AAC.00648.
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  68. NOGUCHI LM, Montgomery ET, Biggio JR, Hendrix CW, et al
    Detectable tenofovir levels in breastfeeding infants of mothers exposed to topical tenofovir.
    Antimicrob Agents Chemother. 2016 Jul 11. pii: AAC.00645.
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  69. LI M, Mislak AC, Foli Y, Agbosu E, et al
    DNA Polymerase-gamma R953C Mutant is Associated with ART-Induced Mitochondrial Toxicity.
    Antimicrob Agents Chemother. 2016 Jul 5. pii: AAC.00976.
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  70. VILLEGAS G, Calenda G, Zhang S, Mizenina O, et al
    In vitro exposure to PC-1005 and cervicovaginal lavages from women vaginally administered PC-1005 inhibit HIV-1 and HSV-2 infection in human cervical mucosa.
    Antimicrob Agents Chemother. 2016 Jul 5. pii: AAC.00392.
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    June 2016
  71. LU Y, Goti V, Chaturvedula A, Haberer JE, et al
    Population pharmacokinetics of tenofovir in HIV-1 uninfected members of sero-discordant couples and effect of dose reporting methods.
    Antimicrob Agents Chemother. 2016 Jun 27. pii: AAC.00559.
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  72. CHEN X, Castillo-Mancilla JR, Seifert SM, McAllister K, et al
    Analysis of the endogenous deoxynucleoside triphosphate pool in HIV positive and negative individuals receiving tenofovir-emtricitabine.
    Antimicrob Agents Chemother. 2016 Jun 27. pii: AAC.01019.
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    May 2016
  73. RIVERO-BUCETA E, Sun L, Gualda BM, Doyaguez EG, et al
    An unexpected twist: optimization of a class of tryptophan dendrimers that inhibit HIV replication leads to a selective, specific and low nanomolar inhibitor of clinical isolates of enterovirus A71.
    Antimicrob Agents Chemother. 2016 May 31. pii: AAC.00626.
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  74. CUSTODIO JM, Fordyce M, Garner W, Vimal M, et al
    Pharmacokinetics and Safety of Tenofovir Alafenamide in HIV-uninfected Subjects with Severe Renal Impairment.
    Antimicrob Agents Chemother. 2016 May 23. pii: AAC.00005.
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  75. VARGAS G, Vincent KL, Zhu Y, Szafron D, et al
    In vivo rectal mucosal barrier function imaging in a large animal model using confocal endomicroscopy: implications for injury assessment and use in HIV prevention studies.
    Antimicrob Agents Chemother. 2016 May 16. pii: AAC.00134.
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  76. CHUNG DH, Golden JE, Adcock RS, Schroeder CE, et al
    Discovery of a broad-spectrum antiviral compound that inhibits pyrimidine biosynthesis and establishes a type 1 interferon-independent antiviral state.
    Antimicrob Agents Chemother. 2016 May 16. pii: AAC.00282.
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  77. WARRILOW AG, Parker JE, Price CL, Nes WD, et al
    The Investigational Drug VT-1129 is a Highly Potent Inhibitor of Cryptococcus species CYP51 but only Weakly Inhibits the Human Enzyme.
    Antimicrob Agents Chemother. 2016 May 9. pii: AAC.00349.
    >> Share


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