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HIV Infection

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Articles published in
PLoS Pathog
    July 2018
  1. DINGENS AS, Acharya P, Haddox HK, Rawi R, et al
    Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV.
    PLoS Pathog. 2018;14:e1007159.
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  2. MARSHALL VA, Labo N, Hao XP, Holdridge B, et al
    Gammaherpesvirus infection and malignant disease in rhesus macaques experimentally infected with SIV or SHIV.
    PLoS Pathog. 2018;14:e1007130.
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    June 2018
  3. YACOOB C, Lange MD, Cohen K, Lathia K, et al
    B cell clonal lineage alterations upon recombinant HIV-1 envelope immunization of rhesus macaques.
    PLoS Pathog. 2018;14:e1007120.
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  4. SHIN YC, Bischof GF, Lauer WA, Gonzalez-Nieto L, et al
    A recombinant herpesviral vector containing a near-full-length SIVmac239 genome produces SIV particles and elicits immune responses to all nine SIV gene products.
    PLoS Pathog. 2018;14:e1007143.
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  5. WANAGURU M, Barry DJ, Benton DJ, O'Reilly NJ, et al
    Murine leukemia virus p12 tethers the capsid-containing pre-integration complex to chromatin by binding directly to host nucleosomes in mitosis.
    PLoS Pathog. 2018;14:e1007117.
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  6. ELLETT F, Pazhakh V, Pase L, Benard EL, et al
    Macrophages protect Talaromyces marneffei conidia from myeloperoxidase-dependent neutrophil fungicidal activity during infection establishment in vivo.
    PLoS Pathog. 2018;14:e1007063.
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  7. GU CJ, Borjabad A, Hadas E, Kelschenbach J, et al
    EcoHIV infection of mice establishes latent viral reservoirs in T cells and active viral reservoirs in macrophages that are sufficient for induction of neurocognitive impairment.
    PLoS Pathog. 2018;14:e1007061.
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    May 2018
  8. RAM DR, Manickam C, Hueber B, Itell HL, et al
    Tracking KLRC2 (NKG2C)+ memory-like NK cells in SIV+ and rhCMV+ rhesus macaques.
    PLoS Pathog. 2018;14:e1007104.
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  9. XU M, Moresco JJ, Chang M, Mukim A, et al
    SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy.
    PLoS Pathog. 2018;14:e1007071.
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  10. ROTEM E, Faingold O, Charni M, Klug YA, et al
    The HTLV-1 gp21 fusion peptide inhibits antigen specific T-cell activation in-vitro and in mice.
    PLoS Pathog. 2018;14:e1007044.
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  11. CROOKS ET, Grimley SL, Cully M, Osawa K, et al
    Glycoengineering HIV-1 Env creates 'supercharged' and 'hybrid' glycans to increase neutralizing antibody potency, breadth and saturation.
    PLoS Pathog. 2018;14:e1007024.
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  12. SCHIFFNER T, Pallesen J, Russell RA, Dodd J, et al
    Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins.
    PLoS Pathog. 2018;14:e1006986.
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    April 2018
  13. ENOSE-AKAHATA Y, Azodi S, Smith BR, Billioux BJ, et al
    Immunophenotypic characterization of CSF B cells in virus-associated neuroinflammatory diseases.
    PLoS Pathog. 2018;14:e1007042.
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  14. LI Z, Mbonye U, Feng Z, Wang X, et al
    The KAT5-Acetyl-Histone4-Brd4 axis silences HIV-1 transcription and promotes viral latency.
    PLoS Pathog. 2018;14:e1007012.
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  15. IKEDA T, Symeonides M, Albin JS, Li M, et al
    HIV-1 adaptation studies reveal a novel Env-mediated homeostasis mechanism for evading lethal hypermutation by APOBEC3G.
    PLoS Pathog. 2018;14:e1007010.
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  16. BARAJAS BC, Tanaka M, Robinson BA, Phuong DJ, et al
    Identifying the assembly intermediate in which Gag first associates with unspliced HIV-1 RNA suggests a novel model for HIV-1 RNA packaging.
    PLoS Pathog. 2018;14:e1006977.
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  17. WETZEL KS, Yi Y, Yadav A, Bauer AM, et al
    Loss of CXCR6 coreceptor usage characterizes pathogenic lentiviruses.
    PLoS Pathog. 2018;14:e1007003.
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  18. BUGGERT M, Nguyen S, McLane LM, Steblyanko M, et al
    Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease.
    PLoS Pathog. 2018;14:e1006973.
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  19. RICHARDSON SI, Chung AW, Natarajan H, Mabvakure B, et al
    HIV-specific Fc effector function early in infection predicts the development of broadly neutralizing antibodies.
    PLoS Pathog. 2018;14:e1006987.
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  20. PETERSON CW, Wang J, Deleage C, Reddy S, et al
    Differential impact of transplantation on peripheral and tissue-associated viral reservoirs: Implications for HIV gene therapy.
    PLoS Pathog. 2018;14:e1006956.
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  21. KUMAR A, Smith CEP, Giorgi EE, Eudailey J, et al
    Infant transmitted/founder HIV-1 viruses from peripartum transmission are neutralization resistant to paired maternal plasma.
    PLoS Pathog. 2018;14:e1006944.
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    March 2018
  22. CONTRERAS X, Salifou K, Sanchez G, Helsmoortel M, et al
    Nuclear RNA surveillance complexes silence HIV-1 transcription.
    PLoS Pathog. 2018;14:e1006950.
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  23. CHITRE AS, Kattah MG, Rosli YY, Pao M, et al
    A20 upregulation during treated HIV disease is associated with intestinal epithelial cell recovery and function.
    PLoS Pathog. 2018;14:e1006806.
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  24. WAGH K, Seaman MS, Zingg M, Fitzsimons T, et al
    Potential of conventional & bispecific broadly neutralizing antibodies for prevention of HIV-1 subtype A, C & D infections.
    PLoS Pathog. 2018;14:e1006860.
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  25. MEYERSON NR, Warren CJ, Vieira DASA, Diaz-Griferro F, et al
    Species-specific vulnerability of RanBP2 shaped the evolution of SIV as it transmitted in African apes.
    PLoS Pathog. 2018;14:e1006906.
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  26. ZHEN A, Peterson CW, Carrillo MA, Reddy SS, et al
    Correction: Long-term persistence and function of hematopoietic stem cell-derived chimeric antigen receptor T cells in a nonhuman primate model of HIV/AIDS.
    PLoS Pathog. 2018;14:e1006891.
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    February 2018
  27. AUCLAIR S, Liu F, Niu Q, Hou W, et al
    Distinct susceptibility of HIV vaccine vector-induced CD4 T cells to HIV infection.
    PLoS Pathog. 2018;14:e1006888.
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  28. KLASSE PJ, Ketas TJ, Cottrell CA, Ozorowski G, et al
    Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.
    PLoS Pathog. 2018;14:e1006913.
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  29. FISHER BS, Green RR, Brown RR, Wood MP, et al
    Liver macrophage-associated inflammation correlates with SIV burden and is substantially reduced following cART.
    PLoS Pathog. 2018;14:e1006871.
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  30. KUHNERT D, Kouyos R, Shirreff G, Pecerska J, et al
    Quantifying the fitness cost of HIV-1 drug resistance mutations through phylodynamics.
    PLoS Pathog. 2018;14:e1006895.
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  31. HASENKRUG KJ, Chougnet CA, Dittmer U
    Regulatory T cells in retroviral infections.
    PLoS Pathog. 2018;14:e1006776.
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  32. WATSON DC, Moysi E, Valentin A, Bergamaschi C, et al
    Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes.
    PLoS Pathog. 2018;14:e1006902.
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  33. HOGAN LE, Vasquez J, Hobbs KS, Hanhauser E, et al
    Increased HIV-1 transcriptional activity and infectious burden in peripheral blood and gut-associated CD4+ T cells expressing CD30.
    PLoS Pathog. 2018;14:e1006856.
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    January 2018
  34. TAKATA M, Soll SJ, Emery A, Blanco-Melo D, et al
    Global synonymous mutagenesis identifies cis-acting RNA elements that regulate HIV-1 splicing and replication.
    PLoS Pathog. 2018;14:e1006824.
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  35. UPADHYAY C, Feyznezhad R, Yang W, Zhang H, et al
    Alterations of HIV-1 envelope phenotype and antibody-mediated neutralization by signal peptide mutations.
    PLoS Pathog. 2018;14:e1006812.
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  36. REH L, Magnus C, Kadelka C, Kuhnert D, et al
    Phenotypic deficits in the HIV-1 envelope are associated with the maturation of a V2-directed broadly neutralizing antibody lineage.
    PLoS Pathog. 2018;14:e1006825.
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  37. GALILEE M, Alian A
    The structure of FIV reverse transcriptase and its implications for non-nucleoside inhibitor resistance.
    PLoS Pathog. 2018;14:e1006849.
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  38. TSO FY, Kossenkov AV, Lidenge SJ, Ngalamika O, et al
    RNA-Seq of Kaposi's sarcoma reveals alterations in glucose and lipid metabolism.
    PLoS Pathog. 2018;14:e1006844.
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  39. ZHAO J, Cheng L, Wang H, Yu H, et al
    Infection and depletion of CD4+ group-1 innate lymphoid cells by HIV-1 via type-I interferon pathway.
    PLoS Pathog. 2018;14:e1006819.
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  40. BINNING JM, Smith AM, Hultquist JF, Craik CS, et al
    Fab-based inhibitors reveal ubiquitin independent functions for HIV Vif neutralization of APOBEC3 restriction factors.
    PLoS Pathog. 2018;14:e1006830.
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  41. KLEIN K, Nickel G, Nankya I, Kyeyune F, et al
    Higher sequence diversity in the vaginal tract than in blood at early HIV-1 infection.
    PLoS Pathog. 2018;14:e1006754.
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  42. CLARRIDGE KE, Blazkova J, Einkauf K, Petrone M, et al
    Effect of analytical treatment interruption and reinitiation of antiretroviral therapy on HIV reservoirs and immunologic parameters in infected individuals.
    PLoS Pathog. 2018;14:e1006792.
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    December 2017
  43. GACH JS, Bouzin M, Wong MP, Chromikova V, et al
    Human Immunodeficiency Virus type-1 (HIV-1) evades antibody-dependent phagocytosis.
    PLoS Pathog. 2017;13:e1006793.
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  44. DAVIS-GARDNER ME, Gardner MR, Alfant B, Farzan M, et al
    eCD4-Ig promotes ADCC activity of sera from HIV-1-infected patients.
    PLoS Pathog. 2017;13:e1006786.
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  45. ZHEN A, Peterson CW, Carrillo MA, Reddy SS, et al
    Long-term persistence and function of hematopoietic stem cell-derived chimeric antigen receptor T cells in a nonhuman primate model of HIV/AIDS.
    PLoS Pathog. 2017;13:e1006753.
    >> Share

  46. GAVEGNANO C, Brehm JH, Dupuy FP, Talla A, et al
    Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors.
    PLoS Pathog. 2017;13:e1006740.
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  47. ZHANG Z, Gu Q, de Manuel Montero M, Bravo IG, et al
    Stably expressed APOBEC3H forms a barrier for cross-species transmission of simian immunodeficiency virus of chimpanzee to humans.
    PLoS Pathog. 2017;13:e1006746.
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    November 2017
  48. MACKELPRANG RD, Bamshad MJ, Chong JX, Hou X, et al
    Whole genome sequencing of extreme phenotypes identifies variants in CD101 and UBE2V1 associated with increased risk of sexually acquired HIV-1.
    PLoS Pathog. 2017;13:e1006703.
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  49. MCBRIDE JA, Striker R
    Imbalance in the game of T cells: What can the CD4/CD8 T-cell ratio tell us about HIV and health?
    PLoS Pathog. 2017;13:e1006624.
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    October 2017
  50. BAILEY AL, Buechler CR, Matson DR, Peterson EJ, et al
    Pegivirus avoids immune recognition but does not attenuate acute-phase disease in a macaque model of HIV infection.
    PLoS Pathog. 2017;13:e1006692.
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  51. ROGANOWICZ MD, Komurlu S, Mukherjee S, Plewka J, et al
    TRIM5alpha SPRY/coiled-coil interactions optimize avid retroviral capsid recognition.
    PLoS Pathog. 2017;13:e1006686.
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  52. PORTILLO JC, Muniz-Feliciano L, Lopez Corcino Y, Lee SJ, et al
    Toxoplasma gondii induces FAK-Src-STAT3 signaling during infection of host cells that prevents parasite targeting by autophagy.
    PLoS Pathog. 2017;13:e1006671.
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  53. LEIBMAN RS, Richardson MW, Ellebrecht CT, Maldini CR, et al
    Supraphysiologic control over HIV-1 replication mediated by CD8 T cells expressing a re-engineered CD4-based chimeric antigen receptor.
    PLoS Pathog. 2017;13:e1006613.
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  54. RATO S, Rausell A, Munoz M, Telenti A, et al
    Single-cell analysis identifies cellular markers of the HIV permissive cell.
    PLoS Pathog. 2017;13:e1006678.
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    September 2017
  55. OBENG-ADJEI N, Portugal S, Holla P, Li S, et al
    Malaria-induced interferon-gamma drives the expansion of Tbethi atypical memory B cells.
    PLoS Pathog. 2017;13:e1006576.
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  56. DEL PRETE GQ, Keele BF, Fode J, Thumar K, et al
    A single gp120 residue can affect HIV-1 tropism in macaques.
    PLoS Pathog. 2017;13:e1006572.
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  57. ABERE B, Mamo TM, Hartmann S, Samarina N, et al
    The Kaposi's sarcoma-associated herpesvirus (KSHV) non-structural membrane protein K15 is required for viral lytic replication and may represent a therapeutic target.
    PLoS Pathog. 2017;13:e1006639.
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  58. ALLARD A, Althouse BM, Hebert-Dufresne L, Scarpino SV, et al
    The risk of sustained sexual transmission of Zika is underestimated.
    PLoS Pathog. 2017;13:e1006633.
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  59. THOMAS AS, Jones KL, Gandhi RT, McMahon DK, et al
    mT-cell responses targeting HIV Nef uniquely correlate with infected cell frequencies after long-term antiretroviral therapy.
    PLoS Pathog. 2017;13:e1006629.
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  60. SEKI S, Nomura T, Nishizawa M, Yamamoto H, et al
    In vivo virulence of MHC-adapted AIDS virus serially-passaged through MHC-mismatched hosts.
    PLoS Pathog. 2017;13:e1006638.
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  61. SHRESTHA P, Davis DA, Veeranna RP, Carey RF, et al
    Hypoxia-inducible factor-1 alpha as a therapeutic target for primary effusion lymphoma.
    PLoS Pathog. 2017;13:e1006628.
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  62. DUBROVSKAYA V, Guenaga J, de Val N, Wilson R, et al
    Targeted N-glycan deletion at the receptor-binding site retains HIV Env NFL trimer integrity and accelerates the elicited antibody response.
    PLoS Pathog. 2017;13:e1006614.
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  63. NAKANO Y, Misawa N, Juarez-Fernandez G, Moriwaki M, et al
    Correction: HIV-1 competition experiments in humanized mice show that APOBEC3H imposes selective pressure and promotes virus adaptation.
    PLoS Pathog. 2017;13:e1006606.
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  64. KIJAK GH, Sanders-Buell E, Chenine AL, Eller MA, et al
    Correction: Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection.
    PLoS Pathog. 2017;13:e1006620.
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  65. Correction: CD4 is expressed on a heterogeneous subset of hematopoietic progenitors, which persistently harbor CXCR4 and CCR5-tropic HIV proviral genomes in vivo.
    PLoS Pathog. 2017;13:e1006617.
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  66. MARSDEN MD, Loy BA, Wu X, Ramirez CM, et al
    In vivo activation of latent HIV with a synthetic bryostatin analog effects both latent cell "kick" and "kill" in strategy for virus eradication.
    PLoS Pathog. 2017;13:e1006575.
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  67. TARTOUR K, Nguyen XN, Appourchaux R, Assil S, et al
    Interference with the production of infectious viral particles and bimodal inhibition of replication are broadly conserved antiviral properties of IFITMs.
    PLoS Pathog. 2017;13:e1006610.
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  68. RADEMEYER C, Korber B, Seaman MS, Giorgi EE, et al
    Correction: Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization.
    PLoS Pathog. 2017;13:e1006641.
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    August 2017
  69. HOTTER D, Krabbe T, Reith E, Gawanbacht A, et al
    Primate lentiviruses use at least three alternative strategies to suppress NF-kappaB-mediated immune activation.
    PLoS Pathog. 2017;13:e1006598.
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  70. BURDICK RC, Delviks-Frankenberry KA, Chen J, Janaka SK, et al
    Dynamics and regulation of nuclear import and nuclear movements of HIV-1 complexes.
    PLoS Pathog. 2017;13:e1006570.
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  71. GORIN AM, Du Y, Liu FY, Zhang TH, et al
    HIV-1 epitopes presented by MHC class I types associated with superior immune containment of viremia have highly constrained fitness landscapes.
    PLoS Pathog. 2017;13:e1006541.
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  72. MATSUDA K, Riddick NE, Lee CA, Puryear SB, et al
    A SIV molecular clone that targets the CNS and induces neuroAIDS in rhesus macaques.
    PLoS Pathog. 2017;13:e1006538.
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  73. MCCRACKEN MK, Gromowski GD, Friberg HL, Lin X, et al
    Impact of prior flavivirus immunity on Zika virus infection in rhesus macaques.
    PLoS Pathog. 2017;13:e1006487.
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    July 2017
  74. LI G, Zhao J, Cheng L, Jiang Q, et al
    HIV-1 infection depletes human CD34+CD38- hematopoietic progenitor cells via pDC-dependent mechanisms.
    PLoS Pathog. 2017;13:e1006505.
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  75. KIJAK GH, Sanders-Buell E, Chenine AL, Eller MA, et al
    Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection.
    PLoS Pathog. 2017;13:e1006510.
    >> Share

  76. SEBASTIAN NT, Zaikos TD, Terry V, Taschuk F, et al
    CD4 is expressed on a heterogeneous subset of hematopoietic progenitors, which persistently harbor CXCR4 and CCR5-tropic HIV proviral genomes in vivo.
    PLoS Pathog. 2017;13:e1006509.
    >> Share

  77. MARTINS MA, Shin YC, Gonzalez-Nieto L, Domingues A, et al
    Vaccine-induced immune responses against both Gag and Env improve control of simian immunodeficiency virus replication in rectally challenged rhesus macaques.
    PLoS Pathog. 2017;13:e1006529.
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  78. BREZAR V, Hani L, Surenaud M, Hubert A, et al
    Negative modulation of suppressive HIV-specific regulatory T cells by IL-2 adjuvanted therapeutic vaccine.
    PLoS Pathog. 2017;13:e1006489.
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  79. CARDOZO EF, Andrade A, Mellors JW, Kuritzkes DR, et al
    Treatment with integrase inhibitor suggests a new interpretation of HIV RNA decay curves that reveals a subset of cells with slow integration.
    PLoS Pathog. 2017;13:e1006478.
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  80. BELL SM, Bedford T
    Modern-day SIV viral diversity generated by extensive recombination and cross-species transmission.
    PLoS Pathog. 2017;13:e1006466.
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  81. HILL AL, Rosenbloom DIS, Goldstein E, Hanhauser E, et al
    Correction: Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIV.
    PLoS Pathog. 2017;13:e1006488.
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  82. TAKEUCHI H, Saito H, Noda T, Miyamoto T, et al
    Phosphorylation of the HIV-1 capsid by MELK triggers uncoating to promote viral cDNA synthesis.
    PLoS Pathog. 2017;13:e1006441.
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  83. INTROINI A, Bostrom S, Bradley F, Gibbs A, et al
    Correction: Seminal plasma induces inflammation and enhances HIV-1 replication in human cervical tissue explants.
    PLoS Pathog. 2017;13:e1006492.
    >> Share

  84. ZHYVOLOUP A, Melamed A, Anderson I, Planas D, et al
    Digoxin reveals a functional connection between HIV-1 integration preference and T-cell activation.
    PLoS Pathog. 2017;13:e1006460.
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    June 2017
  85. BOLTON DL, McGinnis K, Finak G, Chattopadhyay P, et al
    Combined single-cell quantitation of host and SIV genes and proteins ex vivo reveals host-pathogen interactions in individual cells.
    PLoS Pathog. 2017;13:e1006445.
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  86. CAIRNS TM, Ditto NT, Lou H, Brooks BD, et al
    Global sensing of the antigenic structure of herpes simplex virus gD using high-throughput array-based SPR imaging.
    PLoS Pathog. 2017;13:e1006430.
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  87. ELEMANS M, Boelen L, Rasmussen M, Buus S, et al
    HIV-1 adaptation to NK cell-mediated immune pressure.
    PLoS Pathog. 2017;13:e1006361.
    >> Share

  88. XU Z, Asahchop EL, Branton WG, Gelman BB, et al
    MicroRNAs upregulated during HIV infection target peroxisome biogenesis factors: Implications for virus biology, disease mechanisms and neuropathology.
    PLoS Pathog. 2017;13:e1006360.
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    May 2017
  89. INTROINI A, Bostrom S, Bradley F, Gibbs A, et al
    Seminal plasma induces inflammation and enhances HIV-1 replication in human cervical tissue explants.
    PLoS Pathog. 2017;13:e1006402.
    >> Share

  90. KRAMER B, Goeser F, Lutz P, Glassner A, et al
    Compartment-specific distribution of human intestinal innate lymphoid cells is altered in HIV patients under effective therapy.
    PLoS Pathog. 2017;13:e1006373.
    >> Share

  91. SUI Y, Frey B, Wang Y, Billeskov R, et al
    Paradoxical myeloid-derived suppressor cell reduction in the bone marrow of SIV chronically infected macaques.
    PLoS Pathog. 2017;13:e1006395.
    >> Share

  92. NAKANO Y, Misawa N, Juarez-Fernandez G, Moriwaki M, et al
    HIV-1 competition experiments in humanized mice show that APOBEC3H imposes selective pressure and promotes virus adaptation.
    PLoS Pathog. 2017;13:e1006348.
    >> Share

  93. FENNESSEY CM, Pinkevych M, Immonen TT, Reynaldi A, et al
    Genetically-barcoded SIV facilitates enumeration of rebound variants and estimation of reactivation rates in nonhuman primates following interruption of suppressive antiretroviral therapy.
    PLoS Pathog. 2017;13:e1006359.
    >> Share

  94. BRANDENBERG OF, Magnus C, Rusert P, Gunthard HF, et al
    Predicting HIV-1 transmission and antibody neutralization efficacy in vivo from stoichiometric parameters.
    PLoS Pathog. 2017;13:e1006313.
    >> Share

  95. SERRANO-VILLAR S, Sainz T, Ma ZM, Utay NS, et al
    Correction: Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naive to Antiretroviral Therapy: A Pilot Randomized Trial.
    PLoS Pathog. 2017;13:e1006368.
    >> Share

  96. FEDER AF, Kline C, Polacino P, Cottrell M, et al
    A spatio-temporal assessment of simian/human immunodeficiency virus (SHIV) evolution reveals a highly dynamic process within the host.
    PLoS Pathog. 2017;13:e1006358.
    >> Share

    April 2017
  97. GANDHI RT, McMahon DK, Bosch RJ, Lalama CM, et al
    Levels of HIV-1 persistence on antiretroviral therapy are not associated with markers of inflammation or activation.
    PLoS Pathog. 2017;13:e1006285.
    >> Share

    March 2017
  98. MOUSTAFA A, Xie C, Kirkness E, Biggs W, et al
    The blood DNA virome in 8,000 humans.
    PLoS Pathog. 2017;13:e1006292.
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  99. BUI JK, Sobolewski MD, Keele BF, Spindler J, et al
    Proviruses with identical sequences comprise a large fraction of the replication-competent HIV reservoir.
    PLoS Pathog. 2017;13:e1006283.
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  100. BEAUPARLANT D, Rusert P, Magnus C, Kadelka C, et al
    Delineating CD4 dependency of HIV-1: Adaptation to infect low level CD4 expressing target cells widens cellular tropism but severely impacts on envelope functionality.
    PLoS Pathog. 2017;13:e1006255.
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  101. TENFORDE MW, Scriven JE, Harrison TS, Jarvis JN, et al
    Immune correlates of HIV-associated cryptococcal meningitis.
    PLoS Pathog. 2017;13:e1006207.
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    February 2017
  102. YODER AC, Guo K, Dillon SM, Phang T, et al
    The transcriptome of HIV-1 infected intestinal CD4+ T cells exposed to enteric bacteria.
    PLoS Pathog. 2017;13:e1006226.
    >> Share

  103. YASEN A, Herrera R, Rosbe K, Lien K, et al
    Release of HIV-1 sequestered in the vesicles of oral and genital mucosal epithelial cells by epithelial-lymphocyte interaction.
    PLoS Pathog. 2017;13:e1006247.
    >> Share

  104. EASTERHOFF D, Moody MA, Fera D, Cheng H, et al
    Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial.
    PLoS Pathog. 2017;13:e1006182.
    >> Share

  105. BUI JK, Halvas EK, Fyne E, Sobolewski MD, et al
    Ex vivo activation of CD4+ T-cells from donors on suppressive ART can lead to sustained production of infectious HIV-1 from a subset of infected cells.
    PLoS Pathog. 2017;13:e1006230.
    >> Share

  106. IRIMIA A, Serra AM, Sarkar A, Jacak R, et al
    Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.
    PLoS Pathog. 2017;13:e1006212.
    >> Share

  107. TANWAR HS, Khoo KK, Garvey M, Waddington L, et al
    The thermodynamics of Pr55Gag-RNA interaction regulate the assembly of HIV.
    PLoS Pathog. 2017;13:e1006221.
    >> Share

  108. HU Y, O'Boyle K, Auer J, Raju S, et al
    Multiple UBXN family members inhibit retrovirus and lentivirus production and canonical NFkappaBeta signaling by stabilizing IkappaBalpha.
    PLoS Pathog. 2017;13:e1006187.
    >> Share

  109. COMPTON AA, Schwartz O
    They Might Be Giants: Does Syncytium Formation Sink or Spread HIV Infection?
    PLoS Pathog. 2017;13:e1006099.
    >> Share

  110. NEIDLEMAN JA, Chen JC, Kohgadai N, Muller JA, et al
    Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells.
    PLoS Pathog. 2017;13:e1006163.
    >> Share

  111. MAIDJI E, Somsouk M, Rivera JM, Hunt PW, et al
    Replication of CMV in the gut of HIV-infected individuals and epithelial barrier dysfunction.
    PLoS Pathog. 2017;13:e1006202.
    >> Share

    January 2017
  112. HAMMONDS JE, Beeman N, Ding L, Takushi S, et al
    Siglec-1 initiates formation of the virus-containing compartment and enhances macrophage-to-T cell transmission of HIV-1.
    PLoS Pathog. 2017;13:e1006181.
    >> Share

  113. DORIA-ROSE NA, Altae-Tran HR, Roark RS, Schmidt SD, et al
    Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting.
    PLoS Pathog. 2017;13:e1006148.
    >> Share

  114. VIOLLET C, Davis DA, Tekeste SS, Reczko M, et al
    RNA Sequencing Reveals that Kaposi Sarcoma-Associated Herpesvirus Infection Mimics Hypoxia Gene Expression Signature.
    PLoS Pathog. 2017;13:e1006143.
    >> Share

  115. OLIVEIRA MF, Chaillon A, Nakazawa M, Vargas M, et al
    Early Antiretroviral Therapy is Associated with Lower HIV DNA Molecular Diversity and Lower Inflammation in Cerebrospinal Fluid but Does Not Prevent the Establishment of Compartmentalized HIV DNA Populations.
    PLoS Pathog. 2017;13:e1006112.
    >> Share

  116. WIBMER CK, Gorman J, Ozorowski G, Bhiman JN, et al
    Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape.
    PLoS Pathog. 2017;13:e1006074.
    >> Share

  117. WERTHEIM JO, Kosakovsky Pond SL, Forgione LA, Mehta SR, et al
    Social and Genetic Networks of HIV-1 Transmission in New York City.
    PLoS Pathog. 2017;13:e1006000.
    >> Share

  118. AWASTHI S, Hook LM, Shaw CE, Pahar B, et al
    An HSV-2 Trivalent Vaccine Is Immunogenic in Rhesus Macaques and Highly Efficacious in Guinea Pigs.
    PLoS Pathog. 2017;13:e1006141.
    >> Share

  119. HEL Z, Xu J, Denning WL, Helton ES, et al
    Dysregulation of Systemic and Mucosal Humoral Responses to Microbial and Food Antigens as a Factor Contributing to Microbial Translocation and Chronic Inflammation in HIV-1 Infection.
    PLoS Pathog. 2017;13:e1006087.
    >> Share

    December 2016
  120. ROBERTS ER, Carnathan DG, Li H, Shaw GM, et al
    Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques.
    PLoS Pathog. 2016;12:e1006135.
    >> Share

  121. KHASNIS MD, Halkidis K, Bhardwaj A, Root MJ, et al
    Receptor Activation of HIV-1 Env Leads to Asymmetric Exposure of the gp41 Trimer.
    PLoS Pathog. 2016;12:e1006098.
    >> Share

  122. ADNAN S, Reeves RK, Gillis J, Wong FE, et al
    Persistent Low-Level Replication of SIVDeltanef Drives Maturation of Antibody and CD8 T Cell Responses to Induce Protective Immunity against Vaginal SIV Infection.
    PLoS Pathog. 2016;12:e1006104.
    >> Share

  123. HADDOX HK, Dingens AS, Bloom JD
    Experimental Estimation of the Effects of All Amino-Acid Mutations to HIV's Envelope Protein on Viral Replication in Cell Culture.
    PLoS Pathog. 2016;12:e1006114.
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  124. ERICSEN AJ, Lauck M, Mohns MS, DiNapoli SR, et al
    Microbial Translocation and Inflammation Occur in Hyperacute Immunodeficiency Virus Infection and Compromise Host Control of Virus Replication.
    PLoS Pathog. 2016;12:e1006048.
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  125. MEURIS F, Carthagena L, Jaracz-Ros A, Gaudin F, et al
    The CXCL12/CXCR4 Signaling Pathway: A New Susceptibility Factor in Human Papillomavirus Pathogenesis.
    PLoS Pathog. 2016;12:e1006039.
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  126. STABELL AC, Hawkins J, Li M, Gao X, et al
    Non-human Primate Schlafen11 Inhibits Production of Both Host and Viral Proteins.
    PLoS Pathog. 2016;12:e1006066.
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    November 2016
  127. BOULLE M, Muller TG, Dahling S, Ganga Y, et al
    HIV Cell-to-Cell Spread Results in Earlier Onset of Viral Gene Expression by Multiple Infections per Cell.
    PLoS Pathog. 2016;12:e1005964.
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  128. NIKOLOVA M, Wiedemann A, Muhtarova M, Achkova D, et al
    Subset- and Antigen-Specific Effects of Treg on CD8+ T Cell Responses in Chronic HIV Infection.
    PLoS Pathog. 2016;12:e1005995.
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  129. DUENAS-DECAMP M, Jiang L, Bolon D, Clapham PR, et al
    Saturation Mutagenesis of the HIV-1 Envelope CD4 Binding Loop Reveals Residues Controlling Distinct Trimer Conformations.
    PLoS Pathog. 2016;12:e1005988.
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  130. LESLIE GJ, Wang J, Richardson MW, Haggarty BS, et al
    Potent and Broad Inhibition of HIV-1 by a Peptide from the gp41 Heptad Repeat-2 Domain Conjugated to the CXCR4 Amino Terminus.
    PLoS Pathog. 2016;12:e1005983.
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  131. SMITH SA, Burton SL, Kilembe W, Lakhi S, et al
    Diversification in the HIV-1 Envelope Hyper-variable Domains V2, V4, and V5 and Higher Probability of Transmitted/Founder Envelope Glycosylation Favor the Development of Heterologous Neutralization Breadth.
    PLoS Pathog. 2016;12:e1005989.
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  132. WHITE CH, Moesker B, Beliakova-Bethell N, Martins LJ, et al
    Transcriptomic Analysis Implicates the p53 Signaling Pathway in the Establishment of HIV-1 Latency in Central Memory CD4 T Cells in an In Vitro Model.
    PLoS Pathog. 2016;12:e1006026.
    >> Share

  133. PRODGER JL, Gray RH, Shannon B, Shahabi K, et al
    Chemokine Levels in the Penile Coronal Sulcus Correlate with HIV-1 Acquisition and Are Reduced by Male Circumcision in Rakai, Uganda.
    PLoS Pathog. 2016;12:e1006025.
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  134. LIN Z, Cantone J, Lu H, Nowicka-Sans B, et al
    Mechanistic Studies and Modeling Reveal the Origin of Differential Inhibition of Gag Polymorphic Viruses by HIV-1 Maturation Inhibitors.
    PLoS Pathog. 2016;12:e1005990.
    >> Share

    October 2016
  135. MILES B, Miller SM, Folkvord JM, Levy DN, et al
    Follicular Regulatory CD8 T Cells Impair the Germinal Center Response in SIV and Ex Vivo HIV Infection.
    PLoS Pathog. 2016;12:e1005924.
    >> Share

  136. WITTKOPP CJ, Adolph MB, Wu LI, Chelico L, et al
    A Single Nucleotide Polymorphism in Human APOBEC3C Enhances Restriction of Lentiviruses.
    PLoS Pathog. 2016;12:e1005865.
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  137. SUTTIPRAPA S, Rinaldi G, Tsai IJ, Mann VH, et al
    HIV-1 Integrates Widely throughout the Genome of the Human Blood Fluke Schistosoma mansoni.
    PLoS Pathog. 2016;12:e1005931.
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    September 2016
  138. POLICICCHIO BB, Xu C, Brocca-Cofano E, Raehtz KD, et al
    Multi-dose Romidepsin Reactivates Replication Competent SIV in Post-antiretroviral Rhesus Macaque Controllers.
    PLoS Pathog. 2016;12:e1005879.
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  139. RAGHWANI J, Rose R, Sheridan I, Lemey P, et al
    Exceptional Heterogeneity in Viral Evolutionary Dynamics Characterises Chronic Hepatitis C Virus Infection.
    PLoS Pathog. 2016;12:e1005894.
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  140. JARDINE JG, Sok D, Julien JP, Briney B, et al
    Correction: Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.
    PLoS Pathog. 2016;12:e1005905.
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  141. KLASSE PJ, LaBranche CC, Ketas TJ, Ozorowski G, et al
    Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C.
    PLoS Pathog. 2016;12:e1005864.
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  142. CARIAS AM, Allen SA, Fought AJ, Kotnik Halavaty K, et al
    Increases in Endogenous or Exogenous Progestins Promote Virus-Target Cell Interactions within the Non-human Primate Female Reproductive Tract.
    PLoS Pathog. 2016;12:e1005885.
    >> Share

  143. ZEVIN AS, Xie IY, Birse K, Arnold K, et al
    Microbiome Composition and Function Drives Wound-Healing Impairment in the Female Genital Tract.
    PLoS Pathog. 2016;12:e1005889.
    >> Share

  144. DA SILVA SANTOS C, Tartour K, Cimarelli A
    A Novel Entry/Uncoating Assay Reveals the Presence of at Least Two Species of Viral Capsids During Synchronized HIV-1 Infection.
    PLoS Pathog. 2016;12:e1005897.
    >> Share

    August 2016
  145. FENG Y, Tran K, Bale S, Kumar S, et al
    Thermostability of Well-Ordered HIV Spikes Correlates with the Elicitation of Autologous Tier 2 Neutralizing Antibodies.
    PLoS Pathog. 2016;12:e1005767.
    >> Share

  146. DEMERS KR, Makedonas G, Buggert M, Eller MA, et al
    Temporal Dynamics of CD8+ T Cell Effector Responses during Primary HIV Infection.
    PLoS Pathog. 2016;12:e1005805.
    >> Share

  147. PLOQUIN MJ, Madec Y, Casrouge A, Huot N, et al
    Elevated Basal Pre-infection CXCL10 in Plasma and in the Small Intestine after Infection Are Associated with More Rapid HIV/SIV Disease Onset.
    PLoS Pathog. 2016;12:e1005774.
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  148. LASKEY SB, Pohlmeyer CW, Bruner KM, Siliciano RF, et al
    Evaluating Clonal Expansion of HIV-Infected Cells: Optimization of PCR Strategies to Predict Clonality.
    PLoS Pathog. 2016;12:e1005689.
    >> Share

  149. PINKEVYCH M, Cromer D, Tolstrup M, Grimm AJ, et al
    Correction: HIV Reactivation from Latency after Treatment Interruption Occurs on Average Every 5-8 Days-Implications for HIV Remission.
    PLoS Pathog. 2016;12:e1005745.
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  150. PINKEVYCH M, Kent SJ, Tolstrup M, Lewin SR, et al
    Modeling of Experimental Data Supports HIV Reactivation from Latency after Treatment Interruption on Average Once Every 5-8 Days.
    PLoS Pathog. 2016;12:e1005740.
    >> Share

  151. HILL AL, Rosenbloom DI, Siliciano JD, Siliciano RF, et al
    Insufficient Evidence for Rare Activation of Latent HIV in the Absence of Reservoir-Reducing Interventions.
    PLoS Pathog. 2016;12:e1005679.
    >> Share

  152. JARDINE JG, Sok D, Julien JP, Briney B, et al
    Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.
    PLoS Pathog. 2016;12:e1005815.
    >> Share

  153. YORK A, Kutluay SB, Errando M, Bieniasz PD, et al
    The RNA Binding Specificity of Human APOBEC3 Proteins Resembles That of HIV-1 Nucleocapsid.
    PLoS Pathog. 2016;12:e1005833.
    >> Share

  154. BADIA R, Pujantell M, Riveira-Munoz E, Puig T, et al
    The G1/S Specific Cyclin D2 Is a Regulator of HIV-1 Restriction in Non-proliferating Cells.
    PLoS Pathog. 2016;12:e1005829.
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  155. PACE M, Williams J, Kurioka A, Gerry AB, et al
    Histone Deacetylase Inhibitors Enhance CD4 T Cell Susceptibility to NK Cell Killing but Reduce NK Cell Function.
    PLoS Pathog. 2016;12:e1005782.
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  156. TAY MZ, Liu P, Williams LD, McRaven MD, et al
    Antibody-Mediated Internalization of Infectious HIV-1 Virions Differs among Antibody Isotypes and Subclasses.
    PLoS Pathog. 2016;12:e1005817.
    >> Share

    July 2016

  157. Correction: Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIV.
    PLoS Pathog. 2016;12:e1005778.
    >> Share

  158. BOYD DF, Sharma A, Humes D, Cheng-Mayer C, et al
    Adapting SHIVs In Vivo Selects for Envelope-Mediated Interferon-alpha Resistance.
    PLoS Pathog. 2016;12:e1005727.
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  159. RADEMEYER C, Korber B, Seaman MS, Giorgi EE, et al
    Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization.
    PLoS Pathog. 2016;12:e1005742.
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  160. HOFFMANN M, Pantazis N, Martin GE, Hickling S, et al
    Exhaustion of Activated CD8 T Cells Predicts Disease Progression in Primary HIV-1 Infection.
    PLoS Pathog. 2016;12:e1005661.
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  161. FROMENTIN R, Bakeman W, Lawani MB, Khoury G, et al
    CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART.
    PLoS Pathog. 2016;12:e1005761.
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  162. MUIR R, Metcalf T, Tardif V, Takata H, et al
    Altered Memory Circulating T Follicular Helper-B Cell Interaction in Early Acute HIV Infection.
    PLoS Pathog. 2016;12:e1005777.
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    June 2016
  163. ABDEL-MOHSEN M, Chavez L, Tandon R, Chew GM, et al
    Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation.
    PLoS Pathog. 2016;12:e1005677.
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  164. LIU F, Fan X, Auclair S, Ferguson M, et al
    Sequential Dysfunction and Progressive Depletion of Candida albicans-Specific CD4 T Cell Response in HIV-1 Infection.
    PLoS Pathog. 2016;12:e1005663.
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  165. BENDJENNAT M, Saffarian S
    The Race against Protease Activation Defines the Role of ESCRTs in HIV Budding.
    PLoS Pathog. 2016;12:e1005657.
    >> Share

  166. DHARAN A, Talley S, Tripathi A, Mamede JI, et al
    KIF5B and Nup358 Cooperatively Mediate the Nuclear Import of HIV-1 during Infection.
    PLoS Pathog. 2016;12:e1005700.
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  167. FRANCIS AC, Marin M, Shi J, Aiken C, et al
    Time-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living Cells.
    PLoS Pathog. 2016;12:e1005709.
    >> Share

  168. ARRODE-BRUSES G, Goode D, Kleinbeck K, Wilk J, et al
    A Small Molecule, Which Competes with MAdCAM-1, Activates Integrin alpha4beta7 and Fails to Prevent Mucosal Transmission of SHIV-SF162P3.
    PLoS Pathog. 2016;12:e1005720.
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    May 2016
  169. TULLY DC, Ogilvie CB, Batorsky RE, Bean DJ, et al
    Differences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder Virus.
    PLoS Pathog. 2016;12:e1005619.
    >> Share

  170. DELVIKS-FRANKENBERRY KA, Nikolaitchik OA, Burdick RC, Gorelick RJ, et al
    Minimal Contribution of APOBEC3-Induced G-to-A Hypermutation to HIV-1 Recombination and Genetic Variation.
    PLoS Pathog. 2016;12:e1005646.
    >> Share


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