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Articles published in
Antimicrob Agents Chemother
    November 2025
  1. FUNK OG, Li J, Khan I, Cusumano JA, et al
    Ceftobiprole alone versus ampicillin-ceftriaxone against borderline-penicillin-resistant, ampicillin-susceptible, and vancomycin-resistant Enterococcus faecalis isolates.
    Antimicrob Agents Chemother. 2025 Nov 24:e0105025. doi: 10.1128/aac.01050.
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  2. LAVOIE T, Sierra T, Daffinee K, Pogue JM, et al
    Unlocking potentials: the impact of meropenem, meropenem-vaborbactam, and ceftazidime-avibactam in combating carbapenem-resistant Enterobacter cloacae.
    Antimicrob Agents Chemother. 2025 Nov 19:e0090625. doi: 10.1128/aac.00906.
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  3. HASHIMOTO Y, Dao DT, Kasuga I, Takemura T, et al
    Ongoing independent evolution of linezolid and vancomycin-resistance pELF-type linear plasmids across the One Health spectrum.
    Antimicrob Agents Chemother. 2025 Nov 18:e0116825. doi: 10.1128/aac.01168.
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  4. BEH JQ, Wick RR, Howden BP, Connor CH, et al
    Challenges and considerations for whole-genome-based antimicrobial resistance plasmid investigations.
    Antimicrob Agents Chemother. 2025 Nov 11:e0109725. doi: 10.1128/aac.01097.
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  5. FINDLAY J, Nordmann P, Jayol A, Seth-Smith HMB, et al
    Carbapenem resistance in a Klebsiella quasipneumoniae isolate resulting from production of CTX-M-33 and OmpK36 porin deficiency.
    Antimicrob Agents Chemother. 2025 Nov 6:e0121425. doi: 10.1128/aac.01214.
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  6. HE G, Zeng S, Banki LT, Zhou W, et al
    Clinical emergence of inducible macrolide resistance mediated by acquired erm(41) C28T mutation in Mycobacterium abscessus.
    Antimicrob Agents Chemother. 2025 Nov 6:e0115325. doi: 10.1128/aac.01153.
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  7. XUE R, Gao S, de Hoog S, van Diepeningen A, et al
    Olorofim activity against multidrug-resistant Fusarium unveils intra-species and inter-species variability.
    Antimicrob Agents Chemother. 2025;69:e0096125.
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  8. WIEDERHOLD NP
    Case Commentary: Successful use of olorofim for the treatment of multi-drug-resistant Lomentospora prolificans infection in a child.
    Antimicrob Agents Chemother. 2025;69:e0107225.
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  9. MASSIC L, Doorley LA, Jones SJ, Richardson I, et al
    Acquired amphotericin B resistance attributed to a mutated ERG3 in Candidozyma auris.
    Antimicrob Agents Chemother. 2025;69:e0060125.
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  10. RAMIREZ D, Ramirez DM, Arora R, Arthur G, et al
    Noncytotoxic polymyxin derivatives enhance antibiotic action against multidrug-resistant Gram-negative bacteria.
    Antimicrob Agents Chemother. 2025;69:e0071225.
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  11. KUNZ COYNE AJ, Gray R, May E, Curry H, et al
    Molecular and pharmacodynamic insights into beta-lactam therapy for high-inoculum Enterobacter cloacae complex infections.
    Antimicrob Agents Chemother. 2025;69:e0117025.
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  12. WANG C, Feng Y, Zong Z
    Colistin heteroresistance in Enterobacter due to base heterozygosity at certain phoP and phoQ locations.
    Antimicrob Agents Chemother. 2025;69:e0071325.
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  13. LODISE TP, Min J, Nathanson BH, Yucel E, et al
    Comparison of early treatment with ceftolozane/tazobactam versus polymyxin-based therapy of pneumonia due to MDR Pseudomonas aeruginosa (PUMA).
    Antimicrob Agents Chemother. 2025;69:e0056925.
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  14. MORAN-BARRIO J, Giacone L, Brambilla L, Fabbri C, et al
    The lipoprotein biosynthesis pathway: key to OXA-mediated carbapenem resistance in Acinetobacter baumannii.
    Antimicrob Agents Chemother. 2025 Nov 4:e0109925. doi: 10.1128/aac.01099.
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    October 2025
  15. SHAW S, Pragasam AK, Chowdhury G, Samanta P, et al
    Genomic portrayal of emerging carbapenem-resistant El Tor variant Vibrio cholerae O1.
    Antimicrob Agents Chemother. 2025 Oct 17:e0074025. doi: 10.1128/aac.00740.
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  16. FRIAES A, Mamede R, Santos B, Marrao G, et al
    Increase of macrolide resistance among Streptococcus pyogenes pharyngitis driven by a mef(A)-msr(D)/emm2-ST55 lineage in Portugal (2014-2019).
    Antimicrob Agents Chemother. 2025 Oct 10:e0096825. doi: 10.1128/aac.00968.
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  17. ALVARADO CASAS ML, Triana Diaz JA, Montilla-Escudero E, Prada Cardozo DA, et al
    Genomic epidemiology of Colombian resistant Candida auris isolates.
    Antimicrob Agents Chemother. 2025 Oct 7:e0072525. doi: 10.1128/aac.00725.
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  18. DONG X, Xiang Y, Li Y, Zhang Y, et al
    Lineage-specific evolution and resistance-virulence divergence in Klebsiella pneumoniae ST268: a global population genomic analysis.
    Antimicrob Agents Chemother. 2025;69:e0070325.
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  19. RAKA V, Jangra M, Kaur P, Dadwal R, et al
    Preclinical evaluation of tridecaptin M: in vitro and in vivo efficacy against colistin-resistant Gram-negative bacterial pathogens and pharmacokinetics.
    Antimicrob Agents Chemother. 2025;69:e0108325.
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  20. ALARCON RIOS AC, Zwep LB, Vriesendorp B, Knibbe CAJ, et al
    Colistin resistance dynamics in Pseudomonas aeruginosa under biofilm and planktonic growth.
    Antimicrob Agents Chemother. 2025;69:e0042125.
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  21. WAN T-W, Shintani M, Kojima KK, Moriguchi N, et al
    Transposition of Tn552-II (a Tn552 derivative) to the conjugative pCtra plasmid family in pediatric multidrug-resistant community-associated MRSA.
    Antimicrob Agents Chemother. 2025;69:e0064725.
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    September 2025
  22. VENA A, Bartalucci C, Muccio M, Tiseo G, et al
    Comparative effectiveness of echinocandins and liposomal amphotericin B for fluconazole-resistant Candida parapsilosis bloodstream infections.
    Antimicrob Agents Chemother. 2025 Sep 30:e0035525. doi: 10.1128/aac.00355.
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  23. SHINOHARA T, Wada A, Abe M, Oiki S, et al
    A zinc-chelating cyclic alkyl polyamine compound is efficient and safe in a murine model of multidrug-resistant Candida auris infection.
    Antimicrob Agents Chemother. 2025 Sep 26:e0085625. doi: 10.1128/aac.00856.
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  24. PETERSEN S, Diricks M, Utpatel C, Schulenburg H, et al
    Evolution of beta-lactam resistance causes fitness reductions and several cases of collateral sensitivities in the human pathogen Haemophilus influenzae.
    Antimicrob Agents Chemother. 2025 Sep 22:e0057625. doi: 10.1128/aac.00576.
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  25. ZENG Q, Huang H, Lu J, Wu L, et al
    Comparison of different colistin sulfate regimens for carbapenem-resistant gram-negative bacteria pneumonia in neurocritical care patients: a retrospective cohort study.
    Antimicrob Agents Chemother. 2025 Sep 22:e0064425. doi: 10.1128/aac.00644.
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  26. SICELOFF AT, Ohta N, Norman KN, Loneragan GH, et al
    Correction for Siceloff et al., "Antimicrobial Resistance Hidden within Multiserovar Salmonella Populations".
    Antimicrob Agents Chemother. 2025 Sep 18:e0092625. doi: 10.1128/aac.00926.
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  27. MARTIN-VICENTE A, Nywening AV, Xie J, Thorn HI, et al
    Genetic analysis of common triazole resistance mechanisms in a collection of Aspergillus lentulus clinical isolates from the United States.
    Antimicrob Agents Chemother. 2025 Sep 12:e0069025. doi: 10.1128/aac.00690.
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  28. TURNER AM, Kinsella P, Miller WR, Carter GP, et al
    Therapeutic approach to difficult-to-treat multidrug-resistant enterococcal infections.
    Antimicrob Agents Chemother. 2025 Sep 11:e0106024. doi: 10.1128/aac.01060.
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  29. SCANGARELLA-OMAN NE, Butler DL, Breton J, Brown D, et al
    Efficacy and in vitro activity of gepotidacin against bacterial uropathogens, including subsets with molecularly characterized resistance mechanisms and genotypes/epidemiological clones, in females with uncomplicated urinary tract infections: results
    Antimicrob Agents Chemother. 2025 Sep 9:e0163924. doi: 10.1128/aac.01639.
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  30. SCANGARELLA-OMAN NE, Butler DL, Breton J, Brown D, et al
    Efficacy and in vitro activity of gepotidacin against bacterial uropathogens, including drug-resistant phenotypes, in females with uncomplicated urinary tract infections: results from two global, pivotal, phase 3 trials (EAGLE-2 and EAGLE-3).
    Antimicrob Agents Chemother. 2025 Sep 9:e0164024. doi: 10.1128/aac.01640.
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  31. YU H, Peng W, Li H, Zhang Y, et al
    Agricultural propiconazole residues promote triazole cross-resistance in Cryptococcus neoformans through ERG11 and efflux pump overexpression.
    Antimicrob Agents Chemother. 2025;69:e0076525.
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  32. CASTILLO-RAMIREZ S, Aguilar-Vera A, Kumar A, Evans B, et al
    Acinetobacter baumannii: much more than a human pathogen.
    Antimicrob Agents Chemother. 2025;69:e0080125.
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  33. WANG C, Huang H, Valera L, Parcella K, et al
    Preclinical virology profiles of the HIV-1 capsid inhibitors VH4004280 and VH4011499.
    Antimicrob Agents Chemother. 2025 Sep 3:e0030925. doi: 10.1128/aac.00309.
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    August 2025
  34. LAI Y-T, Dingens AS, DeMouth M, Helmold Hait S, et al
    Fostemsavir analog BMS-818251 has enhanced viral neutralization potency and similar escape mutation profile.
    Antimicrob Agents Chemother. 2025 Aug 27:e0191024. doi: 10.1128/aac.01910.
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  35. REITLER P, DeJarnette CA, Kumar R, Tucker KM, et al
    A screen to identify antifungal antagonists reveals a variety of pharmacotherapies that induce echinocandin tolerance in Candida albicans.
    Antimicrob Agents Chemother. 2025 Aug 18:e0048425. doi: 10.1128/aac.00484.
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  36. BARKER KS, Santana DJ, Zhang Q, Peters TL, et al
    Mutations in TAC1B drive increased CDR1 and MDR1 expression and azole resistance in Candida auris.
    Antimicrob Agents Chemother. 2025 Aug 18:e0030025. doi: 10.1128/aac.00300.
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  37. BUYUKYANBOLU E, Argotsinger J, Beck ET, Chamberland RR, et al
    Activity of ampicillin-sulbactam, sulbactam-durlobactam, and comparators against Acinetobacter baumannii-calcoaceticus complex strains isolated from respiratory and bloodstream sources: results from ACNBio study.
    Antimicrob Agents Chemother. 2025;69:e0037925.
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  38. KUBIN CJ, Garzia C, Uhlemann A-C
    Acinetobacter baumannii treatment strategies: a review of therapeutic challenges and considerations.
    Antimicrob Agents Chemother. 2025;69:e0106324.
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  39. SARAL SARIYER A, Leus IV, Tambat R, Farjana M, et al
    Mutations in the proximal binding site and F-loop of AdeJ confer resistance to efflux pump inhibitors.
    Antimicrob Agents Chemother. 2025;69:e0009025.
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  40. MELETIADIS J, Jorgensen KM, Astvad KMT, Abou-Chakra N, et al
    EUCAST olorofim MICs for 3,550 Danish mold and dermatophyte isolates from 2020 to 2023.
    Antimicrob Agents Chemother. 2025;69:e0035325.
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  41. ZHANG W, Peng K, Liu M, Luo X, et al
    Detection of SXT/R391 integrative conjugative elements carrying tigecycline resistance genes in Shewanella spp. isolated from retail seafood.
    Antimicrob Agents Chemother. 2025;69:e0174224.
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  42. VAHEDI-SHAHANDASHTI R, Hofer I, Leighton H, Fothergill J, et al
    The impact of respiratory tract mimicking media on antifungal susceptibility testing.
    Antimicrob Agents Chemother. 2025;69:e0022525.
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  43. OJHA S, Chatterjee P, Beuria TK
    Inhibition of efflux pumps by FDA-approved drugs oxiconazole and sertaconazole restores antibiotic susceptibility in multidrug-resistant S. aureus.
    Antimicrob Agents Chemother. 2025 Aug 4:e0032025. doi: 10.1128/aac.00320.
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    July 2025
  44. VIDUCIC D, Obranic S, Matovina M, Babic F, et al
    Biological cost of aminoglycoside resistance Arm/Kam 16S rRNA methyltransferases from natural antibiotic producers and clinical pathogens.
    Antimicrob Agents Chemother. 2025 Jul 31:e0074225. doi: 10.1128/aac.00742.
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  45. NONG L, Liu X, Wang X, de Leeuw W, et al
    Driving factors for beta-lactam resistance gene amplification during de novo resistance evolution in E. coli.
    Antimicrob Agents Chemother. 2025 Jul 23:e0044125. doi: 10.1128/aac.00441.
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  46. FANG Y, Song M, Zhang Y, Wu Z, et al
    Evolution of XDR Pseudomonas aeruginosa ST463 strains with two plasmids harboring multiple antimicrobial resistance genes.
    Antimicrob Agents Chemother. 2025 Jul 23:e0169724. doi: 10.1128/aac.01697.
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  47. YAMADA AY, de Souza AR, Madalosso G, de Assis DB, et al
    Emergence of carbapenem-resistant Acinetobacter baumannii clonal complex 2 in multiple hospitals in Sao Paulo state, Brazil.
    Antimicrob Agents Chemother. 2025 Jul 23:e0186524. doi: 10.1128/aac.01865.
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  48. WU Y, Dai Y, Lu H, Jiang X, et al
    Osh2 mediates Candida species resistance to miltefosine by regulating zymosterol accumulation.
    Antimicrob Agents Chemother. 2025 Jul 23:e0042725. doi: 10.1128/aac.00427.
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  49. BARKER KS, Patterson HP, Morschhauser J, Cuomo CA, et al
    Mutations in transcription factors that confer fluconazole resistance also confer reduced susceptibility to manogepix in Candida auris (Candidozyma auris), Candida albicans, Candida parapsilosis, and Candida glabrata (Nakaseomyces glabratus).
    Antimicrob Agents Chemother. 2025 Jul 23:e0068025. doi: 10.1128/aac.00680.
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  50. TUANYOK A, Nakajima C, Noll T, Khan MSR, et al
    Genomic insights into ceftazidime resistance in Burkholderia pseudomallei: discovery of A172T mutation and palindromic GC-rich repeat sequences facilitating penA duplication and amplification.
    Antimicrob Agents Chemother. 2025 Jul 21:e0022025. doi: 10.1128/aac.00220.
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  51. BELLO-LOPEZ E, Kawabata A, Cantero J, Mendoza S, et al
    Genomic epidemiology reveals antibiotic resistance transfer and polyclonal dissemination of Acinetobacter baumannii in a Paraguayan hospital.
    Antimicrob Agents Chemother. 2025 Jul 8:e0007725. doi: 10.1128/aac.00077.
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  52. GATTI M, Rinaldi M, Cojutti PG, Bonazzetti C, et al
    A pre-post quasi-experimental study of antimicrobial stewardship exploring the impact of a multidisciplinary approach aimed at attaining an aggressive joint pharmacokinetic/pharmacodynamic target with ceftazidime/avibactam on treatment outcome of KPC-
    Antimicrob Agents Chemother. 2025;69:e0048825.
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  53. HOU Y, Pi R, Jia J, Wu Z, et al
    Limited predictive power of known resistance genes for phenotypic drug resistance in clinical Mycobacterium abscessus complex from Beijing in China.
    Antimicrob Agents Chemother. 2025;69:e0184724.
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  54. FERRREIRA CDO, Leturiondo AL, Dos Santos CG, da Silva JB, et al
    Classic and new candidate markers for drug resistance in a large cohort of leprosy patients from the Amazon state, Brazil.
    Antimicrob Agents Chemother. 2025;69:e0155024.
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  55. OUTEDA-GARCIA M, Garcia-Pose A, Guijarro-Sanchez P, Rodriguez-Coello A, et al
    The novel polymyxin analogue SPR206 exhibits higher activity than colistin against both colistin-susceptible and colistin-resistant strains of Acinetobacter baumannii.
    Antimicrob Agents Chemother. 2025;69:e0194024.
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  56. RAJAKANI SG, Xavier BB, Nguyen NM, Lin Q, et al
    Characterization of genome-wide transpositions induced by colistin exposure in multi-drug-resistant Klebsiella pneumoniae.
    Antimicrob Agents Chemother. 2025;69:e0157424.
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  57. VAHEDI-SHAHANDASHTI R, Moroder E, Lass-Florl C
    Candida parapsilosis and echinocandins: should the clinical laboratory drop anidulafungin Etest from the susceptibility testing panel?
    Antimicrob Agents Chemother. 2025 Jul 1:e0024125. doi: 10.1128/aac.00241.
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    June 2025
  58. ANDREANI J, Truffot A, Tilloy V, Jardin H, et al
    Long-range PCRs and next-generation sequencing to detect cytomegalovirus drug resistance-associated mutations.
    Antimicrob Agents Chemother. 2025 Jun 25:e0014125. doi: 10.1128/aac.00141.
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  59. AI Q, Wang S, Chen Z, Zheng S, et al
    Synergistic antibacterial activity and prevention of drug resistance of daptomycin combined with fosfomycin against methicillin-resistant Staphylococcus aureus.
    Antimicrob Agents Chemother. 2025 Jun 18:e0160924. doi: 10.1128/aac.01609.
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  60. LEUS IV, Zgurskaya HI
    No two are alike: on the role of Klebsiella pneumoniae permeability barriers in antibiotic susceptibility and persistence.
    Antimicrob Agents Chemother. 2025 Jun 17:e0008525. doi: 10.1128/aac.00085.
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  61. MEEKES LM, Heikema AP, Tompa M, Astorga Alsina AL, et al
    Proteogenomic analysis demonstrates increased bla(OXA-48) copy numbers and OmpK36 loss as contributors to carbapenem resistance in Klebsiella pneumoniae.
    Antimicrob Agents Chemother. 2025 Jun 13:e0010725. doi: 10.1128/aac.00107.
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  62. WANG K, Xu J, Lu X, Yin P, et al
    Two novel trimethoprim resistance genes, dfra50 and dfra51, identified in phage-plasmids.
    Antimicrob Agents Chemother. 2025 Jun 12:e0169524. doi: 10.1128/aac.01695.
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  63. WAITES JT, Crabb DM, Ratliff AE, Waites KB, et al
    Antimicrobial susceptibility and genetic mechanisms of resistance of Ureaplasma isolates in North America between 2012 and 2023.
    Antimicrob Agents Chemother. 2025;69:e0186824.
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  64. MATEO-VARGAS MA, Rodriguez-Pallares S, Arca-Suarez J, Lopez-Cerero L, et al
    Emergence of KPC-8-producing K. pneumoniae infection without prior exposure to ceftazidime/avibactam: the threat of de novo infections by ceftazidime/avibactam-resistant KPC variants.
    Antimicrob Agents Chemother. 2025;69:e0149424.
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    May 2025
  65. LIU X, Qu X, Zhang R, Zhang Y, et al
    Synergistic combination of next-generation polymyxin MRX-8 and meropenem against carbapenem-resistant A. baumannii.
    Antimicrob Agents Chemother. 2025 May 27:e0191224. doi: 10.1128/aac.01912.
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  66. XIE L, Li J, Peng Q, Liu X, et al
    Contribution of RND superfamily multidrug efflux pumps AdeABC, AdeFGH, and AdeIJK to antimicrobial resistance and virulence factors in multidrug-resistant Acinetobacter baumannii AYE.
    Antimicrob Agents Chemother. 2025 May 23:e0185824. doi: 10.1128/aac.01858.
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  67. NELSON ME, Little JL, Kristich CJ
    Correction for Nelson et al., "Pbp4 provides transpeptidase activity to the FtsW-PbpB peptidoglycan synthase to drive cephalosporin resistance in Enterococcus faecalis".
    Antimicrob Agents Chemother. 2025 May 20:e0059425. doi: 10.1128/aac.00594.
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  68. LI X, Zhou L, Wang D, Wu Q, et al
    Population pharmacokinetics study on nebulized and intravenous administration of polymyxin B in patients with pneumonia caused by multidrug-resistant gram-negative bacteria.
    Antimicrob Agents Chemother. 2025;69:e0004425.
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  69. HIKAL AF, Zhao S, Foley S, Khan AA, et al
    The newly identified grdA gene confers high-level plazomicin resistance in Salmonella enterica serovars.
    Antimicrob Agents Chemother. 2025;69:e0160624.
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  70. LACROIX M, Moreau J, Zampaloni C, Bissantz C, et al
    In vitro pharmacokinetic/pharmacodynamic modeling of the effect of mucin on polymyxin B activity against Acinetobacter baumannii.
    Antimicrob Agents Chemother. 2025;69:e0153524.
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    April 2025
  71. LEE J, Lee I, Lee K-B, Lee SS, et al
    Comparative effectiveness and safety of colistin-based versus high-dose ampicillin/sulbactam-based combination therapy for nosocomial pneumonia caused by carbapenem-resistant Acinetobacter baumannii.
    Antimicrob Agents Chemother. 2025 Apr 23:e0188024. doi: 10.1128/aac.01880.
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  72. ZHANG Y, Zhou B, Kong J, Hu P, et al
    Prevalence and characteristics of tigecycline- and carbapenem-resistant adeN-truncated Acinetobacter baumannii: a genomic epidemiological analysis.
    Antimicrob Agents Chemother. 2025 Apr 23:e0184324. doi: 10.1128/aac.01843.
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  73. SZEL V, Phelan JE, Georghiou SB, Dolinger DL, et al
    The ahpC c-54t compensatory mutation is not always a valid surrogate for isoniazid resistance in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2025 Apr 22:e0026525. doi: 10.1128/aac.00265.
    >> Share

  74. SHERRY NL, Lee JYH, Giulieri SG, Connor CH, et al
    Genomics for antimicrobial resistance-progress and future directions.
    Antimicrob Agents Chemother. 2025 Apr 14:e0108224. doi: 10.1128/aac.01082.
    >> Share

  75. ARDIZZONI E, Mulders W, De Diego Fuertes M, Hayrapetyan A, et al
    Phenotypic and genotypic resistance to bedaquiline in patients with multi-drug-resistant tuberculosis-experiences from Armenia.
    Antimicrob Agents Chemother. 2025 Apr 9:e0183924. doi: 10.1128/aac.01839.
    >> Share

  76. HUANG H, Chen Y, Zhang L, Wan P, et al
    Identification and characterization of a novel major facilitator superfamily (MFS) efflux pump conferring multidrug resistance in Staphylococcus aureus and Staphylococcus epidermidis.
    Antimicrob Agents Chemother. 2025 Apr 7:e0173924. doi: 10.1128/aac.01739.
    >> Share

  77. SASTRE-FEMENIA MA, Gomis-Font MA, Oliver A
    Mutant prevention concentrations and phenotypic and genomic profiling of first-step resistance mechanisms to classical and novel beta-lactams in Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2025;69:e0194224.
    >> Share

  78. SADER HS, Castanheira M, Arends SJR, Doyle TB, et al
    Antimicrobial susceptibility of Stenotrophomonas maltophilia from United States medical centers (2019-2023).
    Antimicrob Agents Chemother. 2025;69:e0012425.
    >> Share

  79. SAMPER-CATIVIELA C, Torre-Fuentes L, Dieguez-Roda B, Maex M, et al
    Molecular epidemiology of Salmonella Enteritidis in humans and animals in Spain.
    Antimicrob Agents Chemother. 2025;69:e0073824.
    >> Share

  80. MA Y, Pirolo M, Giarratana L, Leth Nielsen K, et al
    Chromosomal genes modulating fosfomycin susceptibility in uropathogenic Escherichia coli: a genome-wide analysis.
    Antimicrob Agents Chemother. 2025;69:e0141724.
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  81. PROENCA AM, Rang CU, Chao L
    A link between aging and persistence.
    Antimicrob Agents Chemother. 2025;69:e0131324.
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  82. HUSSAIN A, Bhando T, Casius A, Gupta R, et al
    Deciphering meropenem persistence in Acinetobacter baumannii facilitates discovery of anti-persister activity of thymol.
    Antimicrob Agents Chemother. 2025;69:e0138124.
    >> Share

    March 2025
  83. SONG Y, An Q, Chen S, Dai H, et al
    Antimicrobial resistance of pet-derived bacteria in China, 2000-2020.
    Antimicrob Agents Chemother. 2025 Mar 26:e0165724. doi: 10.1128/aac.01657.
    >> Share

  84. PEROUTKA-BIGUS N, Brooks EJ, Ramey ME, D'Erasmo H, et al
    Contribution of front-line, standard-of-care drugs to bactericidal responses, resistance emergence, and cure in murine models of easy- or hard-to-treat tuberculosis disease.
    Antimicrob Agents Chemother. 2025 Mar 26:e0190124. doi: 10.1128/aac.01901.
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  85. HUANG H, Wan P, Chen Y, Luo X, et al
    Phenotypic and genetic stepwise changes in Staphylococcus aureus during in vitro adaptive laboratory evolution under the selective pressure of tigecycline.
    Antimicrob Agents Chemother. 2025 Mar 26:e0007225. doi: 10.1128/aac.00072.
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  86. KIM M-J, Zarnowski R, Jones R, Nett JE, et al
    Vesicle inhibition reduces Candida biofilm resistance.
    Antimicrob Agents Chemother. 2025 Mar 26:e0004525. doi: 10.1128/aac.00045.
    >> Share

  87. MAHE A, Verneuil N, Coupri D, Hartke A, et al
    D-alanylation of lipoteichoic acids inhibitor provides anti-virulence and anti-resistance effects against methicillin-resistant Staphylococcus epidermidis.
    Antimicrob Agents Chemother. 2025 Mar 21:e0182224. doi: 10.1128/aac.01822.
    >> Share

  88. MUNITA JM, Tamma PD
    Fighting resistance with redundancy: a path forward for treating antimicrobial-resistant infections?
    Antimicrob Agents Chemother. 2025 Mar 14:e0012125. doi: 10.1128/aac.00121.
    >> Share

  89. PETERSEN ME, Khamas AB, Ostergaard LJ, Jorgensen NP, et al
    Combination therapy delays antimicrobial resistance after adaptive laboratory evolution of Staphylococcus aureus.
    Antimicrob Agents Chemother. 2025 Mar 14:e0148324. doi: 10.1128/aac.01483.
    >> Share

  90. ZHAO L, Li C, Wang M, Zhou M, et al
    Potent antiviral activity of simnotrelvir against key epidemic SARS-CoV-2 variants with a high resistance barrier.
    Antimicrob Agents Chemother. 2025 Mar 10:e0155624. doi: 10.1128/aac.01556.
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  91. YU Z, Hu H, Liu X, Liu J, et al
    Clinical outcomes and pharmacokinetics/pharmacodynamics of intravenous polymyxin B treatment for various site carbapenem-resistant gram-negative bacterial infections: a prospective observational multicenter study.
    Antimicrob Agents Chemother. 2025 Mar 6:e0185924. doi: 10.1128/aac.01859.
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  92. LEMAITRE N, Dewitte A, Rakotomanimana F, Gooden D, et al
    Assessing the threat of Yersinia pestis harboring a multi-resistant IncC plasmid and the efficacy of an antibiotic targeting LpxC.
    Antimicrob Agents Chemother. 2025;69:e0149724.
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  93. ROJAS LJ, Nielsen TB, Pantapalangkoor P, Taracila MA, et al
    Restoring cefepime activity against multidrug-resistant KPC-producing Klebsiella pneumoniae by combination with boronic acid inhibitors, MB076 and S02030.
    Antimicrob Agents Chemother. 2025;69:e0096424.
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  94. DORAZIO AJ, Kline EG, Squires KM, Pogue JM, et al
    Restoring ceftolozane susceptibility: a role for diazabicyclooctane beta-lactamase inhibitors?
    Antimicrob Agents Chemother. 2025;69:e0154324.
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  95. CORNISTEIN W, Balasini C, Nuccetelli Y, Rodriguez VM, et al
    Prevalence and mortality associated with multidrug-resistant infections in adult intensive care units in Argentina (PREV-AR).
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    February 2025
  96. YU H, Wang L, Liu X, Zheng J, et al
    Mechanistic insights into the multitarget synergistic efficacy of farrerol and beta-lactam antibiotics in combating methicillin-resistant Staphylococcus aureus.
    Antimicrob Agents Chemother. 2025 Feb 28:e0155124. doi: 10.1128/aac.01551.
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  97. FU S-Y, Chen X-Z, Yi P-C, Gao J, et al
    Optimizing phage therapy for carbapenem-resistant Enterobacter cloacae bacteremia: insights into dose and timing.
    Antimicrob Agents Chemother. 2025 Feb 26:e0168324. doi: 10.1128/aac.01683.
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  98. FILE TM JR, Ramirez JA, Wilde AM
    New Perspectives on Antimicrobial Agents: Omadacycline for community-acquired pneumonia, skin and soft tissue infections, and nontuberculous mycobacteria (focus on M. abscessus).
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  99. BONCOMPAGNI SR, Riccobono E, Cusi MG, Di Pilato V, et al
    Evidence of dissemination of a clc-type integrative and conjugative element to Stenotrophomonas maltophilia, mediating acquisition of sul1 and other resistance determinants.
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  100. ROSON-CALERO N, Gomis Font MA, Ruiz-Soriano A, Just-Baringo X, et al
    In vitro potentiation of tetracyclines in Pseudomonas aeruginosa by RW01, a new cyclic peptide.
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  101. RODRIGUEZ L, Lee HW, Li J, Martin R, et al
    SARS-CoV-2 resistance analyses from the Phase 3 PINETREE study of remdesivir treatment in nonhospitalized participants.
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  102. GHEBREKRISTOS Y, Ahmed A, Beylis N, Singh S, et al
    Xpert MTB/RIF Ultra-resistant and MTBDRplus-susceptible rifampicin results in people with tuberculosis: utility of FluoroType MTBDR and deep sequencing.
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    January 2025
  103. FORRISTER NM, McCarty TP, Pappas PG
    New Perspectives on Antimicrobial Agents: Rezafungin.
    Antimicrob Agents Chemother. 2025;69:e0064623.
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  104. LI T, Zhu Y, Xiang G, Xu Z, et al
    Adaptive evolution of extensive drug resistance and persistence in epidemic ST11 KPC-producing Klebsiella pneumoniae during antimicrobial chemotherapy.
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  105. KOENIG C, Monogue ML, Shields RK, Sakon CM, et al
    Cefiderocol pharmacokinetics during acute pulmonary exacerbations in hospitalized adult persons with cystic fibrosis.
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  106. HE Z, Huang Y, Li W, Zhang H, et al
    Characterization and genomic analysis of the highly virulent Acinetobacter baumannii ST1791 strain dominating in Anhui, China.
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  107. MORITA D, Mukhopadhyay AK, Chowdhury G, Maruyama F, et al
    Genomic epidemiology and genetic characteristics of clinical Campylobacter species cocirculating in West Bengal, India, 2019, using whole genome analysis.
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  108. WANG J, Liu X, Song Y, Liu Z, et al
    LC-AMP-I1, a novel venom-derived antimicrobial peptide from the wolf spider Lycosa coelestis.
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  109. WIEDERHOLD NP, Patterson HP, Ferrer D, Garcia V, et al
    Olorofim demonstrates in vitro activity against Coccidioides species, including isolates against which fluconazole has reduced activity.
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  110. ZHU Q, Wijnants S, Feil R, Van Genechten W, et al
    The stress-protectant molecule trehalose mediates fluconazole tolerance in Candida glabrata.
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  111. VOGENSEN VB, Singh S, Allende CJ, Engelthaler DM, et al
    Fluoroquinolones and rifampin combination in the backdrop of heteroresistant tuberculosis.
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  112. SADER HS, Smart JI, Mendes RE, Castanheira M, et al
    Ceftobiprole activity against multidrug-resistant Staphylococcus aureus clinical isolates collected in the United States from 2016 through 2022.
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    December 2024
  113. JEHANNE Q, Benejat L, Ducournau A, Aptel J, et al
    Increasing rates of erm(B) and erm(N) in human Campylobacter coli and Campylobacter jejuni erythromycin-resistant isolates between 2018 and 2023 in France.
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  114. OLLINGER TL, Zarnowski R, Parker JE, Kelly SL, et al
    Genetic interaction analysis of Candida glabrata transcription factors CST6 and UPC2A in the regulation of respiration and fluconazole susceptibility.
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  115. ZAGALIOTIS P, Michalik-Provasek J, Mavridou E, Naing E, et al
    Bacteriophage treatment is effective against carbapenem-resistant Klebsiella pneumoniae (KPC) in a neutropenic murine model of gastrointestinal translocation and renal infection.
    Antimicrob Agents Chemother. 2024 Dec 20:e0091924. doi: 10.1128/aac.00919.
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  116. GHATBALE P, Sah GP, Dunham S, Khong E, et al
    In vitro resensitization of multidrug-resistant clinical isolates of Enterococcus faecium and E. faecalis through phage-antibiotic synergy.
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  117. HIRAYAMA T, Miyazaki T, Tanaka R, Kitahori N, et al
    TAC1b mutation in Candida auris decreases manogepix susceptibility owing to increased CDR1 expression.
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  118. HEINE HS, Purcell BK, Duncan C, Miller L, et al
    Evaluation of a potent LpxC inhibitor for post-exposure prophylaxis treatment of antibiotic-resistant Burkholderia pseudomallei in a murine infection model.
    Antimicrob Agents Chemother. 2024 Dec 13:e0129524. doi: 10.1128/aac.01295.
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  119. BLANCO-MARTIN T, Gonzalez-Pinto L, Aja-Macaya P, Rodriguez-Pallares S, et al
    Mutant prevention concentrations, in vitro resistance evolution dynamics, and mechanisms of resistance to imipenem and imipenem/relebactam in carbapenem-susceptible Klebsiella pneumoniae isolates showing ceftazidime/avibactam resistance.
    Antimicrob Agents Chemother. 2024;68:e0112024.
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  120. LE TM, Eubank TA, McKelvey AM, Cao X, et al
    Fidaxomicin resistance in Clostridioides difficile: a systematic review and predictive modeling with RNA polymerase binding sites.
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  121. ZHAO H, Hu Y, Nie D, Li N, et al
    A peptide targeting outer membrane protein A of Acinetobacter baumannii exhibits antibacterial activity by reducing bacterial pathogenicity.
    Antimicrob Agents Chemother. 2024;68:e0056524.
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  122. RODRIGUEZ-PALLARES S, Blanco-Martin T, Lence E, Aja-Macaya P, et al
    In vivo emergence of resistance to ceftazidime/avibactam through modification of chromosomal AmpC beta-lactamase in Klebsiella aerogenes.
    Antimicrob Agents Chemother. 2024;68:e0130724.
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  123. XU T, Wu W, Huang L, Liu B, et al
    Novel plasmid-mediated CMY variant (CMY-192) conferring ceftazidime-avibactam resistance in multidrug-resistant Escherichia coli.
    Antimicrob Agents Chemother. 2024;68:e0090624.
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  124. WANG L, Li Y, Xiu L, Hu L, et al
    Multigeographic clinical assessment of a molecular diagnostic assay for detection of key codons to predict decreased susceptibility or resistance to cephalosporins in Neisseria gonorrhoeae.
    Antimicrob Agents Chemother. 2024;68:e0116524.
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  125. YANG C, Wang L, Lv J, Wen Y, et al
    Effects of different carbapenemase and siderophore production on cefiderocol susceptibility in Klebsiella pneumoniae.
    Antimicrob Agents Chemother. 2024;68:e0101924.
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  126. ARAGAW WW, Gebresilase TT, Negatu DA, Dartois V, et al
    Multidrug tolerance conferred by loss-of-function mutations in anti-sigma factor RshA of Mycobacterium abscessus.
    Antimicrob Agents Chemother. 2024;68:e0105124.
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  127. MELENDEZ JH, Edwards VL, Muniz Tirado A, Hardick J, et al
    Local emergence and global evolution of Neisseria gonorrhoeae with high-level resistance to azithromycin.
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    November 2024
  128. BUSH NG, Diez-Santos I, Sankara Krishna P, Clavijo B, et al
    Insights into antibiotic resistance promoted by quinolone exposure.
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  129. JIA H, Li X, Zhuang Y, Wu Y, et al
    Neural network-based predictions of antimicrobial resistance phenotypes in multidrug-resistant Acinetobacter baumannii from whole genome sequencing and gene expression.
    Antimicrob Agents Chemother. 2024 Nov 14:e0144624. doi: 10.1128/aac.01446.
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  130. HERRERA C, Gomis-Font MA, Lopez-Causape C, Diez-Aguilar M, et al
    Mechanisms leading to in vivo ceftazidime/avibactam resistance development during treatment of GES-5-producing Pseudomonas aeruginosa infections.
    Antimicrob Agents Chemother. 2024;68:e0116424.
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  131. BLANCO-MARTIN T, Lopez-Hernandez I, Aracil B, Gonzalez-Pinto L, et al
    Assessment of the activity and mechanisms of resistance to cefiderocol and combinations of beta-lactams and the novel beta-lactamase inhibitors avibactam, taniborbactam, zidebactam, nacubactam, xeruborbactam, and ANT3310 in emerging double-carbapenema
    Antimicrob Agents Chemother. 2024;68:e0092424.
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  132. SATTLER J, Ernst CM, Zweigner J, Hamprecht A, et al
    High frequency of acquired virulence factors in carbapenemase-producing Klebsiella pneumoniae isolates from a large German university hospital, 2013-2021.
    Antimicrob Agents Chemother. 2024;68:e0060224.
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  133. PUUMALA E, Nabeela S, Thornburg CC, Grkovic T, et al
    Naamidine A reveals a promising zinc-binding strategy for topical antifungal therapy.
    Antimicrob Agents Chemother. 2024;68:e0119424.
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  134. SEREME Y, Faury H, Gravrand V, Ageron E, et al
    Molecular insights into the evolutionary trajectory of a Klebsiella aerogenes clinical isolate with a complex trade-off between resistance and virulence.
    Antimicrob Agents Chemother. 2024;68:e0103624.
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  135. MARTIN MJ, Luo TL, Kovalchuk V, Kondratiuk V, et al
    Detection of cefiderocol and aztreonam/avibactam resistance in epidemic Escherichia coli ST-361 carrying bla(NDM-5) and bla(KPC-3) from foreign fighters evacuated from Ukraine.
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  136. OKE MT, Martz K, Mocanita M, Knezevic S, et al
    Analysis of Acinetobacter P-type type IV secretion system-encoding plasmid diversity uncovers extensive secretion system conservation and diverse antibiotic resistance determinants.
    Antimicrob Agents Chemother. 2024 Nov 4:e0103824. doi: 10.1128/aac.01038.
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    October 2024
  137. KON H, Lurie-Weinberger MN, Bechor M, Temkin E, et al
    bla(GES)-producing ST654 comprises a quarter of all carbapenem-resistant Pseudomonas aeruginosa in blood isolates from 15 hospitals.
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  138. LI J, Brandalise D, Coste AT, Sanglard D, et al
    Exploration of novel mechanisms of azole resistance in Candida auris.
    Antimicrob Agents Chemother. 2024 Oct 31:e0126524. doi: 10.1128/aac.01265.
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  139. MA Z, Zeng W, Liu H, Chen H, et al
    Characterization of novel sequence type 12531 and O8:H7 serotype carbapenem-resistant Escherichia coli with strong swimming and intestinal epithelial cell barrier migration abilities.
    Antimicrob Agents Chemother. 2024 Oct 23:e0080524. doi: 10.1128/aac.00805.
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  140. ZARSKE M, Werckenthin C, Golz JC, Stingl K, et al
    The point mutation A1387G in the 16S rRNA gene confers aminoglycoside resistance in Campylobacter jejuni and Campylobacter coli.
    Antimicrob Agents Chemother. 2024 Oct 15:e0083324. doi: 10.1128/aac.00833.
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  141. KENT AG, Spicer LM, Campbell D, Breaker E, et al
    Sentinel Surveillance reveals phylogenetic diversity and detection of linear plasmids harboring vanA and optrA among enterococci collected in the United States.
    Antimicrob Agents Chemother. 2024 Oct 15:e0059124. doi: 10.1128/aac.00591.
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  142. HONG H, Fan L, Shi W, Zhu Y, et al
    Overexpression of beta-lactamase genes (bla(KPC,) bla(SHV)) and novel CirA deficiencies contribute to decreased cefiderocol susceptibility in carbapenem-resistant Klebsiella pneumoniae before its approval in China.
    Antimicrob Agents Chemother. 2024 Oct 10:e0075424. doi: 10.1128/aac.00754.
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  143. SALAMA EA, Elgammal Y, Utturkar SM, Lanman NA, et al
    Overcoming amphotericin B resistance in Candida auris using the antiemetic drug rolapitant.
    Antimicrob Agents Chemother. 2024 Oct 10:e0055624. doi: 10.1128/aac.00556.
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  144. KAUR JN, Klem JF, Liu Y, Boissonneault KR, et al
    Maximally precise combinations to overcome metallo-beta-lactamase-producing Klebsiella pneumoniae.
    Antimicrob Agents Chemother. 2024;68:e0077024.
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  145. LI H, Oliver A, Shields RK, Kamat S, et al
    Molecular characterization of clinically isolated Pseudomonas aeruginosa with varying resistance to ceftazidime-avibactam and ceftolozane-tazobactam collected as a part of the ATLAS global surveillance program from 2020 to 2021.
    Antimicrob Agents Chemother. 2024;68:e0067024.
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  146. STURARO MC, Damaceno NdS, Faccin ID, Silva ON, et al
    Synergistic antimicrobial combination of third-generation cephalosporins and polymyxin B against carbapenem-polymyxin-resistant Klebsiella pneumoniae: an in vitro and in vivo analysis.
    Antimicrob Agents Chemother. 2024;68:e0093024.
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  147. HUANG H, Yang H, Feng S, Zhang X, et al
    High salt condition alters LPS synthesis and induces the emergence of drug resistance mutations in Helicobacter pylori.
    Antimicrob Agents Chemother. 2024;68:e0058724.
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  148. RUBIO J, Yan J, Miller S, Cheng J, et al
    Polymyxins retain in vitro activity and in vivo efficacy against "resistant" Acinetobacter baumannii strains when tested in physiological conditions.
    Antimicrob Agents Chemother. 2024;68:e0072524.
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  149. SINGH V, Nandanwar H
    IMT-P8 potentiates Gram-positive specific antibiotics in intrinsically resistant Gram-negative bacteria.
    Antimicrob Agents Chemother. 2024;68:e0075324.
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  150. HAREZA DA, Cosgrove SE, Bonomo RA, Dzintars K, et al
    Clinical outcomes and emergence of resistance of Pseudomonas aeruginosa infections treated with ceftolozane-tazobactam versus ceftazidime-avibactam.
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  151. WOOD GE, Lee JW, Peramuna T, Wendt KL, et al
    The fungal natural product fusidic acid demonstrates potent activity against Mycoplasma genitalium.
    Antimicrob Agents Chemother. 2024;68:e0100624.
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  152. GAONA M, Corral J, Campoy S, Barbe J, et al
    The novel MFS efflux pump SxtP, regulated by the LysR-type transcriptional activator SxtR, is involved in the susceptibility to sulfamethoxazole/trimethoprim (SXT) and the pathogenesis of Acinetobacter baumannii.
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  153. KOLLER BH, Jania LA, Li H, Barker WT, et al
    Adjuvants restore colistin sensitivity in mouse models of highly colistin-resistant isolates, limiting bacterial proliferation and dissemination.
    Antimicrob Agents Chemother. 2024;68:e0067124.
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  154. ALLAIN M, Morel-Journel T, Condamine B, Gibeaux B, et al
    IncC plasmid genome rearrangements influence the vertical and horizontal transmission tradeoff in Escherichia coli.
    Antimicrob Agents Chemother. 2024;68:e0055424.
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  155. DUBEY V, Farrington N, Harper N, Johnson A, et al
    Acinetobacter baumannii transformants expressing oxacillinases and metallo-beta-lactamases that confer resistance to meropenem: new tools for anti-Acinetobacter drug development and AMR preparedness.
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  156. XU J-Y, Dong H-h, Liao L-j, Yang S-x, et al
    Deoxyshikonin: a promising lead drug grass against drug resistance or sensitivity to Helicobacter pylori in an acidic environment.
    Antimicrob Agents Chemother. 2024;68:e0095924.
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  157. YASMIN M, Marshall SH, Chen L, Rhoads DD, et al
    A molecular analysis of meropenem-vaborbactam non-susceptible KPC-producing Klebsiella pneumoniae.
    Antimicrob Agents Chemother. 2024;68:e0020824.
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  158. FUKUSHIMA K, Matsumoto Y, Abe Y, Hashimoto K, et al
    Variability of macrolide-resistant profile in Mycobacterium avium complex pulmonary disease.
    Antimicrob Agents Chemother. 2024 Oct 8:e0121324. doi: 10.1128/aac.01213.
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    September 2024
  159. RHODES J, Jacobs J, Dennis EK, Manjari SR, et al
    What makes Candida auris pan-drug resistant? Integrative insights from genomic, transcriptomic, and phenomic analysis of clinical strains resistant to all four major classes of antifungal drugs.
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  160. CASTANHEIRA M, Deshpande LM, Rhomberg PR, Carvalhaes CG, et al
    Recent increase in Candida auris frequency in the SENTRY surveillance program: antifungal activity and genotypic characterization.
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  161. LE RUN E, Tettelin H, Holland SM, Zelazny AM, et al
    Evolution toward extremely high imipenem resistance in Mycobacterium abscessus outbreak strains.
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  162. KOMORI K, Aoki K, Harada S, Ishii Y, et al
    Plasmid-mediated acquisition and chromosomal integration of bla(CTX-M-14) in a subclade of Escherichia coli ST131-H30 clade C1.
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  163. XUE J, Li S, Wang L, Zhao Y, et al
    Enhanced fatty acid biosynthesis by Sigma28 in stringent responses contributes to multidrug resistance and biofilm formation in Helicobacter pylori.
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    August 2024
  164. MARTINI MC, Alonso MN, Cafiero JH, Xiao J, et al
    Loss of glycerol catabolism confers carbon-source-dependent artemisinin resistance in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2024 Aug 28:e0064524. doi: 10.1128/aac.00645.
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  165. TIAN P, Li Q-Q, Guo M-J, Zhu Y-Z, et al
    Zidovudine in synergistic combination with nitrofurantoin or omadacycline: in vitro and in murine urinary tract or lung infection evaluation against multidrug-resistant Klebsiella pneumoniae.
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  166. TAO L, Dahlquist A, Harris H, Jacobs E, et al
    Multicenter evaluation of activity of aztreonam in combination with avibactam, relebactam, and vaborbactam against metallo-beta-lactamase-producing carbapenem-resistant gram-negative bacilli.
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  167. HEINE HS, Drusano G, Purcell BK, Anastasiou D, et al
    Omadacycline is active in vitro and in vivo against ciprofloxacin-resistant Bacillus anthracis.
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  168. JACOBS MR, Abdelhamed AM, Good CE, Mack AR, et al
    ARGONAUT-III and -V: susceptibility of carbapenem-resistant Klebsiella pneumoniae and multidrug-resistant Pseudomonas aeruginosa to the bicyclic boronate beta-lactamase inhibitor taniborbactam combined with cefepime.
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  169. ROTONDO CM, Wright GD
    Efficacy of aspergillomarasmine A/meropenem combinations with and without avibactam against bacterial strains producing multiple beta-lactamases.
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  170. EISHA S, Morris AJ, Martin I, Yau YCW, et al
    Effect of L-arginine on cystic fibrosis Pseudomonas aeruginosa biofilms.
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  171. EGGE SL, Rizvi SA, Simar SR, Alcalde M, et al
    Cefiderocol heteroresistance associated with mutations in TonB-dependent receptor genes in Pseudomonas aeruginosa of clinical origin.
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  172. PONTA G, Morena V, Strano M, Molteni C, et al
    Safety of rezafungin as a long-term treatment option in two patients with complicated fungal infections: two cases from Lecco Hospital (Italy).
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    July 2024
  173. NELSON ME, Little JL, Kristich CJ
    Pbp4 provides transpeptidase activity to the FtsW-PbpB peptidoglycan synthase to drive cephalosporin resistance in Enterococcus faecalis.
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  174. ADELMAN MW, Andes DR
    Case Commentary: Extending our therapeutic range against multidrug-resistant Candida.
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  175. TRUONG-BOLDUC QC, Wang Y, Lawton BG, Brown Harding H, et al
    Phenazine-1 carboxylic acid of Pseudomonas aeruginosa induces the expression of Staphylococcus aureus Tet38 MDR efflux pump and mediates resistance to phenazines and antibiotics.
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  176. GIGANTE V, Alm RA, Melchiorri D, Rocke T, et al
    Multi-year analysis of the global preclinical antibacterial pipeline: trends and gaps.
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  177. STRAHILEVITZ J, Motro Y, Temper V, Merezhko D, et al
    In vivo selection of carbapenem resistance during persistent Klebsiella pneumoniae sequence type 395 bloodstream infection due to OmpK36 deletion.
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  178. DULYAYANGKUL P, Sealey JE, Lee WWY, Satapoomin N, et al
    Improving nitrofurantoin resistance prediction in Escherichia coli from whole-genome sequence by integrating NfsA/B enzyme assays.
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  179. BEREDAKI M-I, Arendrup MC, Pournaras S, Meletiadis J, et al
    Comparative pharmacodynamics and dose optimization of liposomal amphotericin B against Candida species in an in vitro pharmacokinetic/pharmacodynamic model.
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    June 2024
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    The intrinsic macrolide resistome of Escherichia coli.
    Antimicrob Agents Chemother. 2024 Jun 28:e0045224. doi: 10.1128/aac.00452.
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  181. KURTZHALS ML, Norman A, Svensson E, Lillebaek T, et al
    Applying whole genome sequencing to predict phenotypic drug resistance in Mycobacterium tuberculosis: leveraging 20 years of nationwide data from Denmark.
    Antimicrob Agents Chemother. 2024 Jun 21:e0043024. doi: 10.1128/aac.00430.
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  182. PLUMET L, Magnan C, Ahmad-Mansour N, Sotto A, et al
    The zebrafish embryo model: unveiling its potential for investigating phage therapy against methicillin-resistant Staphylococcus aureus infection.
    Antimicrob Agents Chemother. 2024 Jun 20:e0056124. doi: 10.1128/aac.00561.
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  183. SON JE, Park SH, Choi U, Lee C-R, et al
    Lytic transglycosylase repertoire diversity enables intrinsic antibiotic resistance and daughter cell separation in Escherichia coli under acidic stress.
    Antimicrob Agents Chemother. 2024 Jun 17:e0037224. doi: 10.1128/aac.00372.
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  184. DIAMOND TL, Goh SL, Ngo W, Rodriguez S, et al
    No antagonism or cross-resistance and a high barrier to the emergence of resistance in vitro for the combination of islatravir and lenacapavir.
    Antimicrob Agents Chemother. 2024 Jun 12:e0033424. doi: 10.1128/aac.00334.
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  185. PETERSIEL N, Giulieri S, Daniel DS, Fan S-H, et al
    Genomic investigation and clinical correlates of the in vitro beta-lactam: NaHCO(3) responsiveness phenotype among methicillin-resistant Staphylococcus aureus isolates from a randomized clinical trial.
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  186. MINUK LM, Brode SK, Mehrabi M, Sharma MK, et al
    Phenotypic amikacin resistance may not indicate poor response to amikacin in Mycobacterium avium complex pulmonary disease.
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    May 2024
  187. HUANG E, Thompson RN, Moon SH, Keck JM, et al
    Treatment-emergent cefiderocol resistance in carbapenem-resistant Acinetobacter baumannii is associated with insertion sequence ISAba36 in the siderophore receptor pirA.
    Antimicrob Agents Chemother. 2024 May 29:e0029024. doi: 10.1128/aac.00290.
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  188. ANOY MMI, Kim W-J, Gelston S, Fleming D, et al
    Evaluation of treatment of methicillin-resistant Staphylococcus aureus biofilms with intermittent electrochemically generated H(2)O(2) or HOCl.
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  189. LUO J, Liu M, Ai W, Zheng X, et al
    Synergy of lytic phage pB23 and meropenem combination against carbapenem-resistant Acinetobacter baumannii.
    Antimicrob Agents Chemother. 2024 May 14:e0044824. doi: 10.1128/aac.00448.
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  190. BERGIN S, Doorley LA, Rybak JM, Wolfe KH, et al
    Analysis of clinical Candida parapsilosis isolates reveals copy number variation in key fluconazole resistance genes.
    Antimicrob Agents Chemother. 2024 May 7:e0161923. doi: 10.1128/aac.01619.
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  191. TAKEMOTO K, Nakayama R, Fujimoto K, Suzuki Y, et al
    In vitro and in vivo activities of KSP-1007, a broad-spectrum inhibitor of serine- and metallo-beta-lactamases, in combination with meropenem against carbapenem-resistant Gram-negative bacteria.
    Antimicrob Agents Chemother. 2024 May 6:e0160223. doi: 10.1128/aac.01602.
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  192. SCHALKWIJK HH, Shewakramani NR, Das K, Andrei G, et al
    Combination of ganciclovir and trifluridine prevents drug-resistance emergence in HSV-1.
    Antimicrob Agents Chemother. 2024;68:e0011024.
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  193. VEGA AD, DeRonde K, Jimenez A, Piazza M, et al
    Difficult-to-treat (DTR) Pseudomonas aeruginosa harboring Verona-Integron metallo-beta-lactamase (bla(VIM)): infection management and molecular analysis.
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  194. MILLER AA, Moussa SH, McLeod SM
    Characterization of Acinetobacter baumannii-calcoaceticus complex isolates and microbiological outcome for patients treated with sulbactam-durlobactam in a phase 3 trial (ATTACK).
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  195. ISHII M, Yamada T, Ishikawa K, Ichinose K, et al
    The Ptk2-Pma1 pathway enhances tolerance to terbinafine in Trichophyton rubrum.
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  196. GHOSH S, Orman MA
    Exploring the links between SOS response, mutagenesis, and resistance during the recovery period.
    Antimicrob Agents Chemother. 2024;68:e0146223.
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  197. CASTANHEIRA M, Kimbrough JH, Lindley J, Doyle TB, et al
    In vitro development of resistance against antipseudomonal agents: comparison of novel beta-lactam/beta-lactamase inhibitor combinations and other beta-lactam agents.
    Antimicrob Agents Chemother. 2024;68:e0136323.
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  198. XIA L, Li Y, Wang Y, Zhou H, et al
    Quorum-sensing regulation of phenazine production heightens Pseudomonas aeruginosa resistance to ciprofloxacin.
    Antimicrob Agents Chemother. 2024;68:e0011824.
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  199. SUZUKI D, Sakurai A, Wakuda M, Suzuki M, et al
    Clinical and genomic characteristics of IMP-producing Enterobacter cloacae complex and Klebsiella pneumoniae.
    Antimicrob Agents Chemother. 2024;68:e0167223.
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  200. NIELSEN TK, Petersen IB, Xu L, Barbuti MD, et al
    The Spx stress regulator confers high-level beta-lactam resistance and decreases susceptibility to last-line antibiotics in methicillin-resistant Staphylococcus aureus.
    Antimicrob Agents Chemother. 2024 May 1:e0033524. doi: 10.1128/aac.00335.
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    April 2024
  201. PETRAITIS V, Petraitiene R, Kavaliauskas P, Naing E, et al
    Development of rabbit models of ventilator-associated bacterial pneumonia produced by carbapenem-resistant Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2024 Apr 30:e0020524. doi: 10.1128/aac.00205.
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  202. SHAFER WM, Conn GL
    Ensuring a sustained workforce to combat antibiotic resistance in the 21st century: the critical need for training the next-gen of scientists at the pre-doctoral level.
    Antimicrob Agents Chemother. 2024 Apr 19:e0024424. doi: 10.1128/aac.00244.
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  203. LYU Z, Ling Y, van Hoof A, Ling J, et al
    Inactivation of the ribosome assembly factor RimP causes streptomycin resistance and impairs motility in Salmonella.
    Antimicrob Agents Chemother. 2024 Apr 17:e0000224. doi: 10.1128/aac.00002.
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  204. HARTUIS S, Ourliac-Garnier I, Robert E, Albassier M, et al
    Precise genome editing underlines the distinct contributions of mutations in ERG11, ERG3, MRR1, and TAC1 genes to antifungal resistance in Candida parapsilosis.
    Antimicrob Agents Chemother. 2024 Apr 16:e0002224. doi: 10.1128/aac.00022.
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  205. LOSSOUARN J, Beurrier E, Bouteau A, Moncaut E, et al
    The virtue of training: extending phage host spectra against vancomycin-resistant Enterococcus faecium strains using the Appelmans method.
    Antimicrob Agents Chemother. 2024 Apr 9:e0143923. doi: 10.1128/aac.01439.
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  206. TENG T, Chen S, Huo F, Jia J, et al
    Efflux pump effects on levofloxacin resistance in Mycobacterium abscessus.
    Antimicrob Agents Chemother. 2024 Apr 4:e0134823. doi: 10.1128/aac.01348.
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  207. SHANG Y, Zhang Y, Wang R, Peng Y, et al
    Deciphering the molecular and functional basis of TMexCD1: the plasmid-encoded efflux pump of resistance-nodulation-division superfamily.
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  208. RIBEIRO DOS SANTOS A, Gade L, Misas E, Litvintseva AP, et al
    Bimodal distribution of azole susceptibility in Sporothrix brasiliensis isolates in Brazil.
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  209. TAIT JR, Anderson D, Nation RL, Creek DJ, et al
    Identifying and mathematically modeling the time-course of extracellular metabolic markers associated with resistance to ceftolozane/tazobactam in Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2024;68:e0108123.
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  210. YANO H, Hayashi W, Kawakami S, Aoki S, et al
    Nationwide genome surveillance of carbapenem-resistant Pseudomonas aeruginosa in Japan.
    Antimicrob Agents Chemother. 2024 Apr 2:e0166923. doi: 10.1128/aac.01669.
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    March 2024
  211. MAIA AR, Cezard A, Fouquenet D, Vasseur V, et al
    Preventive nasal administration of flagellin restores antimicrobial effect of gentamicin and protects against a multidrug-resistant strain of Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2024 Mar 25:e0136123. doi: 10.1128/aac.01361.
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  212. SEGAWA T, Masuda K, Hisatsune J, Ishida-Kuroki K, et al
    Genomic analysis of inter-hospital transmission of vancomycin-resistant Enterococcus faecium sequence type 80 isolated during an outbreak in Hiroshima, Japan.
    Antimicrob Agents Chemother. 2024 Mar 20:e0171623. doi: 10.1128/aac.01716.
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  213. SUN L, Zhuang H, Chen M, Chen Y, et al
    Vancomycin heteroresistance caused by unstable tandem amplifications of the vanM gene cluster on linear conjugative plasmids in a clinical Enterococcus faecium.
    Antimicrob Agents Chemother. 2024 Mar 20:e0115923. doi: 10.1128/aac.01159.
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  214. LI W, He Z, Di W, Xu W, et al
    Transposition mechanism of ISApl1-the determinant of colistin resistance dissemination.
    Antimicrob Agents Chemother. 2024;68:e0123123.
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  215. ANDRE C, Van Camp AG, Ung L, Gilmore MS, et al
    Characterization of the resistome and predominant genetic lineages of Gram-positive bacteria causing keratitis.
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  216. CARUSO L, Mellini M, Catalano Gonzaga O, Astegno A, et al
    Hydrogen sulfide production does not affect antibiotic resistance in Pseudomonas aeruginosa.
    Antimicrob Agents Chemother. 2024 Mar 6:e0007524. doi: 10.1128/aac.00075.
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    February 2024
  217. ZHANG M, Yang B, Shi J, Wang Z, et al
    Host defense peptides mitigate the spread of antibiotic resistance in physiologically relevant condition.
    Antimicrob Agents Chemother. 2024 Feb 28:e0126123. doi: 10.1128/aac.01261.
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  218. MULATO A, Lansdon E, Aoyama R, Voigt J, et al
    Preclinical characterization of a non-peptidomimetic HIV protease inhibitor with improved metabolic stability.
    Antimicrob Agents Chemother. 2024 Feb 21:e0137323. doi: 10.1128/aac.01373.
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  219. FREIBERG JA, Tao L, Manuel C, Mike LA, et al
    A multi-species outbreak of VIM-producing carbapenem-resistant bacteria in a burn unit and subsequent investigation of rapid development of cefiderocol resistance.
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  220. BASSERES E, Eubank TA, Begum K, Alam MJ, et al
    Antibacterial activity of ibezapolstat against antimicrobial-resistant clinical strains of Clostridioides difficile.
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  221. ERSOY SC, Proctor RA, Rose WE, Abdelhady W, et al
    Sensitizing methicillin-resistant Staphylococcus aureus (MRSA) to cefuroxime: the synergic effect of bicarbonate and the wall teichoic acid inhibitor ticlopidine.
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  222. PITOUT JDD, Peirano G, Matsumura Y, DeVinney R, et al
    Escherichia coli sequence type 410 with carbapenemases: a paradigm shift within E. coli toward multidrug resistance.
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  223. DRUSIN SI, Le Terrier C, Poirel L, Bonomo RA, et al
    Structural basis of metallo-beta-lactamase resistance to taniborbactam.
    Antimicrob Agents Chemother. 2024;68:e0116823.
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    January 2024
  224. JIANG X, Li D, Sun Z, Lu Y, et al
    Type I BREX system defends against antibiotic-resistant plasmids in Escherichia coli.
    Antimicrob Agents Chemother. 2024 Jan 30:e0112823. doi: 10.1128/aac.01128.
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  225. IOVLEVA A, McElheny CL, Fowler EL, Cober E, et al
    In vitro activity of sulbactam-durlobactam against colistin-resistant and/or cefiderocol-non-susceptible, carbapenem-resistant Acinetobacter baumannii collected in U.S. hospitals.
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  226. ZALACAIN M, Achard P, Llanos A, Morrissey I, et al
    Meropenem-ANT3310, a unique beta-lactam-beta-lactamase inhibitor combination with expanded antibacterial spectrum against Gram-negative pathogens including carbapenem-resistant Acinetobacter baumannii.
    Antimicrob Agents Chemother. 2024 Jan 30:e0112023. doi: 10.1128/aac.01120.
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  227. AXELL-HOUSE DB, Simar SR, Panesso D, Rincon S, et al
    LiaX is a surrogate marker for cell envelope stress and daptomycin non-susceptibility in Enterococcus faecium.
    Antimicrob Agents Chemother. 2024 Jan 30:e0106923. doi: 10.1128/aac.01069.
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  228. ALDEJOHANN AM, Menner C, Thielemann N, Martin R, et al
    In vitro activity of ibrexafungerp against clinically relevant echinocandin-resistant Candida strains.
    Antimicrob Agents Chemother. 2024 Jan 11:e0132423. doi: 10.1128/aac.01324.
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  229. TERAN N, Egge SL, Phe K, Baptista RP, et al
    The emergence of cefiderocol resistance in Pseudomonas aeruginosa from a heteroresistant isolate during prolonged therapy.
    Antimicrob Agents Chemother. 2024;68:e0100923.
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  230. CHEN T, Yao J, Quan K, Xu J, et al
    Repurposing a human acetyl-CoA carboxylase inhibitor firsocostat to treat fungal candidiasis alone and in combination.
    Antimicrob Agents Chemother. 2024;68:e0113123.
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    December 2023
  231. TAKEMURA M, Nakamura R, Ota M, Nakai R, et al
    In vitro and in vivo activity of cefiderocol against Achromobacter spp. and Burkholderia cepacia complex, including carbapenem-non-susceptible isolates.
    Antimicrob Agents Chemother. 2023;67:e0034623.
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    November 2023
  232. ZHAO J, Pu D, Li Z, Liu X, et al
    In vitro activity of cefiderocol, a siderophore cephalosporin, against carbapenem-resistant hypervirulent Klebsiella pneumoniae in China.
    Antimicrob Agents Chemother. 2023 Nov 28:e0073523. doi: 10.1128/aac.00735.
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  233. JIAO F, Bao Y, Li M, Zhang Y, et al
    Unraveling the mechanism of ceftaroline-induced allosteric regulation in penicillin-binding protein 2a: insights for novel antibiotic development against methicillin-resistant Staphylococcus aureus.
    Antimicrob Agents Chemother. 2023 Nov 16:e0089523. doi: 10.1128/aac.00895.
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  234. DIAZ-GARCIA J, Machado M, Alcala L, Reigadas E, et al
    Trends in antifungal resistance in Candida from a multicenter study conducted in Madrid (CANDIMAD study): fluconazole-resistant C. parapsilosis spreading has gained traction in 2022.
    Antimicrob Agents Chemother. 2023;67:e0098623.
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  235. BOSCH A, Macha ME, Ren Q, Kohler P, et al
    Resistance development in Escherichia coli to delafloxacin at pHs 6.0 and 7.3 compared to ciprofloxacin.
    Antimicrob Agents Chemother. 2023;67:e0162522.
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  236. SCHILDKRAUT JA, Raaijmakers J, Aarnoutse R, Hoefsloot W, et al
    The role of rifampicin within the treatment of Mycobacterium avium pulmonary disease.
    Antimicrob Agents Chemother. 2023;67:e0087423.
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  237. YAMADA T, Maeda M, Nagai H, Salamin K, et al
    Two different types of tandem sequences mediate the overexpression of TinCYP51B in azole-resistant Trichophyton indotineae.
    Antimicrob Agents Chemother. 2023;67:e0093323.
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    October 2023
  238. JIANG S, Chen M, Zhang J, Ba X, et al
    Profiling daptomycin resistance among diverse methicillin-resistant Staphylococcus aureus lineages in China.
    Antimicrob Agents Chemother. 2023 Oct 30:e0056323. doi: 10.1128/aac.00563.
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  239. ZHANG S-P, Ye Y-P, Hou J, Ye Z-R, et al
    Antitoxin MqsA decreases antibiotic susceptibility through the global regulator AgtR in Pseudomonas fluorescens.
    Antimicrob Agents Chemother. 2023 Oct 25:e0081223. doi: 10.1128/aac.00812.
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  240. TAKAHASHI H, Morita M, Kamiya H, Fukusumi M, et al
    Emergence of ciprofloxacin- and penicillin-resistant Neisseria meningitidis isolates in Japan between 2003 and 2020 and its genetic features.
    Antimicrob Agents Chemother. 2023 Oct 24:e0074423. doi: 10.1128/aac.00744.
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  241. LAU JZ, Kuo SH, Belo Y, Malach E, et al
    Antibacterial efficacy of an ultra-short palmitoylated random peptide mixture in mouse models of infection by carbapenem-resistant Klebsiella pneumoniae.
    Antimicrob Agents Chemother. 2023 Oct 11:e0057423. doi: 10.1128/aac.00574.
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  242. KUHBACHER A, Merschak P, Haas H, Liebl M, et al
    The cytochrome P450 reductase CprA is a rate-limiting factor for Cyp51A-mediated azole resistance in Aspergillus fumigatus.
    Antimicrob Agents Chemother. 2023 Oct 10:e0091823. doi: 10.1128/aac.00918.
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  243. LOMOVSKAYA O, Castanheira M, Lindley J, Rubio-Aparicio D, et al
    In vitro potency of xeruborbactam in combination with multiple beta-lactam antibiotics in comparison with other beta-lactam/beta-lactamase inhibitor (BLI) combinations against carbapenem-resistant and extended-spectrum beta-lactamase-producing Enterob
    Antimicrob Agents Chemother. 2023 Oct 6:e0044023. doi: 10.1128/aac.00440.
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    September 2023
  244. MIRON-OCAMPO A, Beattie SR, Guin S, Conway T, et al
    CWHM-974 is a fluphenazine derivative with improved antifungal activity against Candida albicans due to reduced susceptibility to multidrug transporter-mediated resistance mechanisms.
    Antimicrob Agents Chemother. 2023 Sep 13:e0056723. doi: 10.1128/aac.00567.
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  245. PODOLL JD, Rosen E, Wang W, Gao Y, et al
    A small-molecule membrane fluidizer re-sensitizes methicillin-resistant Staphylococcus aureus (MRSA) to beta-lactam antibiotics.
    Antimicrob Agents Chemother. 2023 Sep 8:e0005123. doi: 10.1128/aac.00051.
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