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Colorectal Neoplasms

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Cancer Res
    November 2017

  1. Correction: A Squalene-Based Nanomedicine for Oral Treatment of Colon Cancer.
    Cancer Res. 2017;77:6048.
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    October 2017
  2. LULLA AR, Slifker MJ, Zhou Y, Lev A, et al
    miR-6883 family miRNAs target CDK4/6 to induce G1 phase cell cycle arrest in colon cancer cells.
    Cancer Res. 2017 Oct 23. pii: canres.1767.2017.
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  3. KIM SY, Jung JH, Lee HJ, Soh H, et al
    [18F]fluorothymidine positron emission tomography informs the synergistic efficacy of capecitabine and trifluridine/tipiracil in colon cancer.
    Cancer Res. 2017 Oct 20. pii: canres.1406.2017.
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  4. HUANG S, Fantini D, Merrill B, Bagchi S, et al
    DDB2 is a Novel Regulator of Wnt-Signaling in Colon Cancer.
    Cancer Res. 2017 Oct 11. pii: canres.1570.2017.
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  5. TANG YC, Yuwen H, Wang K, Bruno PM, et al
    Aneuploid Cell Survival Relies upon Sphingolipid Homeostasis.
    Cancer Res. 2017;77:5272-5286.
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    September 2017
  6. ZHOU X, Geng L, Wang D, Yi H, et al
    R-Spondin1/LGR5 Activates TGFbeta Signaling and Suppresses Colon Cancer Metastasis.
    Cancer Res. 2017 Sep 22. pii: canres.0219.2017.
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  7. KATHER JN, Poleszczuk J, Suarez-Carmona M, Krisam J, et al
    In silico modeling of immunotherapy and stroma-targeting therapies in human colorectal cancer.
    Cancer Res. 2017 Sep 18. pii: canres.2006.2017.
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  8. LI P, Wuthrick E, Rappaport JA, Kraft C, et al
    GUCY2C Signaling Opposes the Acute Radiation-Induced GI Syndrome.
    Cancer Res. 2017;77:5095-5106.
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  9. TAKADA M, Zhang W, Suzuki A, Kuroda TS, et al
    FBW7 Loss Promotes Chromosomal Instability and Tumorigenesis via Cyclin E1/CDK2-Mediated Phosphorylation of CENP-A.
    Cancer Res. 2017;77:4881-4893.
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    August 2017
  10. JIN L, Vu T, Yuan G, Datta PK, et al
    STRAP promotes stemness of human colorectal cancer via epigenetic regulation of the NOTCH pathway.
    Cancer Res. 2017 Aug 21. pii: canres.0286.2017.
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  11. ZHAO Y, Ting KK, Li J, Cogger VC, et al
    Targeting Vascular Endothelial-Cadherin in Tumor-Associated Blood Vessels Promotes T-cell-Mediated Immunotherapy.
    Cancer Res. 2017;77:4434-4447.
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  12. MARELLI G, Erreni M, Anselmo A, Taverniti V, et al
    Heme-oxygenase-1 Production by Intestinal CX3CR1+ Macrophages Helps to Resolve Inflammation and Prevents Carcinogenesis.
    Cancer Res. 2017;77:4472-4485.
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    July 2017
  13. JERMYN M, Mercier J, Aubertin K, Desroches J, et al
    Highly Accurate Detection of Cancer In Situ with Intraoperative, Label-Free, Multimodal Optical Spectroscopy.
    Cancer Res. 2017;77:3942-3950.
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    June 2017
  14. HOU PC, Li YH, Lin SC, Lin SC, et al
    Hypoxia-induced downregulation of DUSP-2 phosphatase drives colon cancer stemness.
    Cancer Res. 2017 Jun 26. pii: canres.2990.2016.
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  15. KONDELIN J, Gylfe AE, Lundgren S, Tanskanen T, et al
    Comprehensive evaluation of protein coding mononucleotide microsatellites in microsatellite-unstable colorectal cancer.
    Cancer Res. 2017 Jun 13. pii: canres.0682.2017.
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  16. YOKOYAMA Y, Watanabe T, Tamura Y, Hashizume Y, et al
    Autocrine BMP-4 signaling is a therapeutic target in colorectal cancer.
    Cancer Res. 2017 Jun 13. pii: canres.0112.2017.
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    May 2017
  17. KLOOSTERMAN WP, Coebergh van den Braak RRJ, Pieterse M, van Roosmalen MJ, et al
    A systematic analysis of oncogenic gene fusions in primary colon cancer.
    Cancer Res. 2017 May 16. pii: canres.3563.2017.
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  18. TOMKOVICH S, Yang Y, Winglee K, Gauthier J, et al
    Locoregional Effects of Microbiota in a Preclinical Model of Colon Carcinogenesis.
    Cancer Res. 2017;77:2620-2632.
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  19. VISWANATHAN V, Damle S, Zhang T, Opdenaker LM, et al
    An miRNA expression signature for the human colonic stem cell niche distinguishes malignant from normal epithelia.
    Cancer Res. 2017 May 9. pii: canres.2388.2016.
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  20. LANG M, Berry D, Passecker K, Mesteri I, et al
    HuR Small-Molecule Inhibitor Elicits Differential Effects in Adenomatosis Polyposis and Colorectal Carcinogenesis.
    Cancer Res. 2017;77:2424-2438.
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    April 2017
  21. WANG D, Sun H, Wei J, Cen B, et al
    CXCL1 is critical for pre-metastatic niche formation and metastasis in colorectal cancer.
    Cancer Res. 2017 Apr 28. pii: canres.3199.2016.
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  22. HUANG B, Yang H, Cheng X, Wang D, et al
    tRF/miR-1280 suppresses stem cell-like cells and metastasis in colorectal cancer.
    Cancer Res. 2017 Apr 26. pii: canres.3146.2016.
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  23. KOTELEVETS L, Chastre E, Caron J, Mougin J, et al
    A squalene-based nanomedicine for oral treatment of colon cancer.
    Cancer Res. 2017 Apr 17. pii: canres.1741.2016.
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  24. NIMANONG S, Ostroumov D, Wingerath J, Knocke S, et al
    CD40 Signaling Drives Potent Cellular Immune Responses in Heterologous Cancer Vaccinations.
    Cancer Res. 2017;77:1918-1926.
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  25. EDUATI F, Doldan-Martelli V, Klinger B, Cokelaer T, et al
    Drug resistance mechanisms in colorectal cancer dissected with cell type-specific dynamic logic models.
    Cancer Res. 2017 Apr 5. pii: canres.0078.2017.
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    March 2017
  26. HSIAO KY, Lin YC, Gupta SK, Chang N, et al
    Non-coding effects of circular RNA CCDC66 promote colon cancer growth and metastasis.
    Cancer Res. 2017 Mar 1. pii: canres.1883.2016.
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  27. TIE G, Yan J, Khair L, Messina J, et al
    Hypercholesterolemia increases colorectal cancer incidence by reducing production of NKT and gammadelta T cells from hematopoietic stem cells.
    Cancer Res. 2017 Mar 1. pii: canres.1916.2016.
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  28. QIAO G, Qin J, Kunda N, Calata J, et al
    LIGHT elevation enhances immune eradication of colon cancer metastases.
    Cancer Res. 2017 Mar 1. pii: canres.1655.2016.
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  29. FANG M, Li Y, Huang K, Qi S, et al
    IL-33 promotes colon cancer cell stemness via JNK activation and macrophage recruitment.
    Cancer Res. 2017 Mar 1. pii: canres.1602.2016.
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  30. MAHNE AE, Mauze S, Joyce-Shaikh B, Xia J, et al
    Dual Roles for Regulatory T-cell Depletion and Costimulatory Signaling in Agonistic GITR Targeting for Tumor Immunotherapy.
    Cancer Res. 2017;77:1108-1118.
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    February 2017
  31. BLAJ C, Schmidt EM, Lamprecht S, Hermeking H, et al
    Oncogenic effects of high MAPK activity in colorectal cancer mark progenitor cells and persist irrespective of RAS mutations.
    Cancer Res. 2017 Feb 15. pii: canres.2821.2016.
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  32. TONG J, Wang P, Tan S, Chen D, et al
    Mcl-1 degradation is required for targeted therapeutics to eradicate colon cancer cells.
    Cancer Res. 2017 Feb 15. pii: canres.3242.2016.
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    January 2017
  33. ROKAVEC M, Hermeking H
    Cellular model of colon cancer progression reveals signatures of mRNAs, miRNA, lncRNAs and epigenetic modifications associated with metastasis.
    Cancer Res. 2017 Jan 27. pii: canres.3236.2016.
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  34. MATHOT L, Kundu S, Ljungstrom V, Svedlund J, et al
    Somatic ephrin receptor mutations are associated with metastasis in primary colorectal cancer.
    Cancer Res. 2017 Jan 20. pii: canres.1921.2016.
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  35. REYNAUD C, Ferreras L, Di Mauro P, Kan C, et al
    Lysyl Oxidase Is a Strong Determinant of Tumor Cell Colonization in Bone.
    Cancer Res. 2017;77:268-278.
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  36. VIENNOIS E, Merlin D, Gewirtz AT, Chassaing B, et al
    Dietary Emulsifier-Induced Low-Grade Inflammation Promotes Colon Carcinogenesis.
    Cancer Res. 2017;77:27-40.
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  37. KANG DW, Lee SW, Hwang WC, Lee BH, et al
    Phospholipase D1 Acts through Akt/TopBP1 and RB1 to Regulate the E2F1-Dependent Apoptotic Program in Cancer Cells.
    Cancer Res. 2017;77:142-152.
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  38. TIAN X, Nguyen M, Foote HP, Caster JM, et al
    CRLX101, a Nanoparticle-Drug Conjugate Containing Camptothecin, Improves Rectal Cancer Chemoradiotherapy by Inhibiting DNA Repair and HIF1alpha.
    Cancer Res. 2017;77:112-122.
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    November 2016
  39. CEJAS P, Cavazza A, Yandava C, Moreno V, et al
    Transcriptional regulator CNOT3 defines an aggressive colorectal cancer subtype.
    Cancer Res. 2016 Nov 29. pii: canres.1346.2016.
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  40. USHIJIMA T, Yoshino T
    The Moment that KRAS Mutation Started to Evolve into Precision Medicine in Metastatic Colorectal Cancer.
    Cancer Res. 2016;76:6443-6444.
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    October 2016
  41. ZHANG M, Xu C, Wen L, Han MK, et al
    A hyaluronidase responsive nanoparticle-based drug delivery system for targeting colon cancer cells.
    Cancer Res. 2016 Oct 14. pii: canres.1681.2016.
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  42. ESSIEN BE, Sundaresan S, Ocadiz-Ruiz R, Chavis A, et al
    Transcription factor ZBP-89 drives a feedforward loop of beta-catenin expression in colorectal cancer.
    Cancer Res. 2016 Oct 10. pii: canres.3150.2015.
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    September 2016
  43. HORN T, Ferretti S, Ebel N, Tam A, et al
    High order drug combinations are required to effectively kill colorectal cancer cells.
    Cancer Res. 2016 Sep 22. pii: canres.3425.2015.
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    August 2016
  44. DI CECILIA S, Zhang F, Sancho-Medina A, Li S, et al
    RBM-AS1 is critical for self-renewal of colon cancer stem-like cells.
    Cancer Res. 2016 Aug 12. pii: canres.1824.2015.
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  45. LIMAGNE E, Euvrard R, Thibaudin M, Rebe C, et al
    Accumulation of MDSC and Th17 cells in patients with metastatic colorectal cancer predict the efficacy of a FOLFOX-bevacizumab drug treatment regimen.
    Cancer Res. 2016 Aug 5. pii: canres.3164.2015.
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    Commentary on "KRAS Mutation Status Is Predictive of Response to Cetuximab Therapy in Colorectal Cancer".
    Cancer Res. 2016;76:4309-10.
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    July 2016
    Colon Cancer Germline Genetics: The Unbelievable Year 1993 and Thereafter.
    Cancer Res. 2016;76:4025-7.
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    June 2016
  48. SU L, Luo Y, Yang Z, Yang J, et al
    MEF2D transduces microenvironment stimuli to ZEB1 to promote epithelial-mesenchymal transition and metastasis in colorectal cancer.
    Cancer Res. 2016 Jun 30. pii: canres.0246.2016.
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  49. KUO WT, Lee TC, Yu LC
    Eritoran suppresses colon cancer by altering a functional balance in Toll-like receptors that bind lipopolysaccharide.
    Cancer Res. 2016 Jun 21. pii: canres.0172.2016.
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  50. ODDO D, Sennott EM, Barault L, Valtorta E, et al
    Molecular landscape of acquired resistance to targeted therapy combinations in BRAF mutant colorectal cancer.
    Cancer Res. 2016 Jun 16. pii: canres.0396.2016.
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    May 2016
  51. ALEKSANDROVA K, Giuseppe RD, Isermann B, Biemann R, et al
    Circulating Omentin as a Novel Biomarker for Colorectal Cancer Risk: Data from the EPIC - Potsdam Cohort Study.
    Cancer Res. 2016 May 23. pii: canres.3464.2015.
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  52. ZHOU J, Wang H, Zhang H, Lutz AM, et al
    VEGFR2-targeted three-dimensional ultrasound imaging can predict responses to anti-angiogenic therapy in preclinical models of colon cancer.
    Cancer Res. 2016 May 20. pii: canres.3271.2015.
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  53. GIRAUD J, Failla LM, Pascussi JM, Lagerqvist EL, et al
    Autocrine secretion of progastrin promotes the survival and self-renewal of colon cancer stem-like cells.
    Cancer Res. 2016 May 4. pii: canres.1497.2015.
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    April 2016
  54. FEHRINGER G, Kraft P, Pharoah PD, Eeles RA, et al
    Cross-cancer genome-wide analysis of lung, ovary, breast, prostate and colorectal cancer reveals novel pleiotropic associations.
    Cancer Res. 2016 Apr 20. pii: canres.2980.2015.
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  55. HOUSSEAU F, Wu S, Wick EC, Fan H, et al
    Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis.
    Cancer Res. 2016;76:2115-24.
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  56. SRINIVASAN T, Walters J, Bu P, Than EB, et al
    NOTCH Signaling Regulates Asymmetric Cell Fate of Fast- and Slow-Cycling Colon Cancer Initiating Cells.
    Cancer Res. 2016 Apr 11. pii: canres.3198.2015.
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    March 2016
  57. RAYNAL NJ, Lee JT, Wang Y, Beaudry A, et al
    Targeting Calcium Signaling Induces Epigenetic Reactivation of Tumor Suppressor Genes in Cancer.
    Cancer Res. 2016;76:1494-505.
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    February 2016
  58. RAO CV, Sanghera S, Zhang Y, Biddick L, et al
    Systemic Chromosome Instability Resulted in Colonic Transcriptomic Changes in Metabolic, Proliferation, and Stem Cell Regulators in Sgo1-/+ Mice.
    Cancer Res. 2016;76:630-42.
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  59. MARUSIAK AA, Stephenson NL, Baik H, Trotter EW, et al
    Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis.
    Cancer Res. 2016;76:724-35.
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    January 2016
  60. XING C, Lu XX, Guo PD, Shen T, et al
    Ubiquitin-Specific Protease 4-Mediated Deubiquitination and Stabilization of PRL-3 Is Required for Potentiating Colorectal Oncogenesis.
    Cancer Res. 2016;76:83-95.
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  61. TAVARE R, Escuin-Ordinas H, Mok S, McCracken MN, et al
    An Effective Immuno-PET Imaging Method to Monitor CD8-Dependent Responses to Immunotherapy.
    Cancer Res. 2016;76:73-82.
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