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Chronic Heart Failure

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Articles published in
Proc Natl Acad Sci U S A
    August 2025
  1. SCOTT B, Greenberg L, Squarci C, Campbell KS, et al
    Danicamtiv reduces myosin's working stroke but activates the thin filament by accelerating actomyosin attachment.
    Proc Natl Acad Sci U S A. 2025;122:e2515786122.
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    June 2025
  2. MIOTTO MC, Luna-Figueroa E, Tchagou C, Bahlouli L, et al
    Targeting ryanodine receptors with allopurinol and xanthine derivatives for the treatment of cardiac and musculoskeletal weakness disorders.
    Proc Natl Acad Sci U S A. 2025;122:e2422082122.
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    May 2025
  3. WANG Q, Wang Y, Lin Y, Zhou J, et al
    Thymic Bmi-1 hampers gammadeltaT17 generation and its derived RORgammat-IL-17A signaling to delay cardiac aging.
    Proc Natl Acad Sci U S A. 2025;122:e2414717122.
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  4. SUN Q, Tian X, Tan L, Deng Y, et al
    Multiscale biased chemical space remodeling for developing APLNR agonists with anti-HFpEF efficacy.
    Proc Natl Acad Sci U S A. 2025;122:e2423432122.
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    March 2025
  5. ZAGLIA T, Campo A, Moro N, Di Mauro V, et al
    Enhancement of mitochondrial calcium uptake is cardioprotective against maladaptive hypertrophy by retrograde signaling uptuning Akt.
    Proc Natl Acad Sci U S A. 2025;122:e2402639122.
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    August 2024
  6. TEITGEN AE, Hock MT, McCabe KJ, Childers MC, et al
    Multiscale modeling shows how 2'-deoxy-ATP rescues ventricular function in heart failure.
    Proc Natl Acad Sci U S A. 2024;121:e2322077121.
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    May 2023
  7. REITZ CJ, Tavassoli M, Kim DH, Shah S, et al
    Proteomics and phosphoproteomics of failing human left ventricle identifies dilated cardiomyopathy-associated phosphorylation of CTNNA3.
    Proc Natl Acad Sci U S A. 2023;120:e2212118120.
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