Amedeo's Top 20

Amedeo Smart

Independent Medical Education

13 March 2023

Multidisciplinary Journal Club

  1. Heyland DK, Patel J, Compher C, Rice TW, et al.
    The effect of higher protein dosing in critically ill patients with high nutritional risk (EFFORT Protein): an international, multicentre, pragmatic, registry-based randomised trial.
    Lancet 2023.

  1. Wang Y, Li S, Pan Y, Li H, et al.
    Tenecteplase versus alteplase in acute ischaemic cerebrovascular events (TRACE-2): a phase 3, multicentre, open-label, randomised controlled, non-inferiority trial.
    Lancet 2023.

  2. Leichsenring F, Heim N, Leweke F, Spitzer C, et al.
    Borderline Personality Disorder: A Review.
    JAMA 2023;329:670-679.

  3. Gartlehner G, Dobrescu A, Chapman A, Toromanova A, et al.
    Nonpharmacologic and Pharmacologic Treatments of Adult Patients With Major Depressive Disorder: A Systematic Review and Network Meta-analysis for a Clinical Guideline by the American College of Physicians.
    Ann Intern Med 2023;176:196-211.

  4. Qaseem A, Owens DK, Etxeandia-Ikobaltzeta I, Tufte J, et al.
    Nonpharmacologic and Pharmacologic Treatments of Adults in the Acute Phase of Major Depressive Disorder: A Living Clinical Guideline From the American College of Physicians.
    Ann Intern Med 2023;176:239-252.

  1. Guerrero A, Campo LD, Piscaglia F, Scheiner B, et al.
    Anticoagulation improves survival in patients with cirrhosis and portal vein thrombosis: The IMPORTAL competing-risk meta-analysis.
    J Hepatol 2023.

  2. Azizi M, Saxena M, Wang Y, Jenkins JS, et al.
    Endovascular Ultrasound Renal Denervation to Treat Hypertension: The RADIANCE II Randomized Clinical Trial.
    JAMA 2023;329:651-661.

  3. Giri S, Tronvik E, Linde M, Pedersen SA, et al.
    Randomized controlled studies evaluating Topiramate, Botulinum toxin type A, and mABs targeting CGRP in patients with chronic migraine and medication overuse headache: A systematic review and meta-analysis.
    Cephalalgia 2023;43:333102423115692.

  4. Wallace ND, Dunne MT, McArdle O, Small C, et al.
    Efficacy and toxicity of primary re-irradiation for malignant spinal cord compression based on radiobiological modelling: a phase II clinical trial.
    Br J Cancer 2023;128:576-585.

  5. Mitja O, Alemany A, Marks M, Lezama Mora JI, et al.
    Mpox in people with advanced HIV infection: a global case series.
    Lancet 2023.

  1. Haghdoost F, Puledda F, Garcia-Azorin D, Huessler EM, et al.
    Evaluating the efficacy of CGRP mAbs and gepants for the preventive treatment of migraine: A systematic review and network meta-analysis of phase 3 randomised controlled trials.
    Cephalalgia 2023;43:333102423115936.

  2. Jha MK, Mathew SJ.
    Pharmacotherapies for Treatment-Resistant Depression: How Antipsychotics Fit in the Rapidly Evolving Therapeutic Landscape.
    Am J Psychiatry 2023;180:190-199.

  3. Sachs GS, Yeung PP, Rekeda L, Khan A, et al.
    Adjunctive Cariprazine for the Treatment of Patients With Major Depressive Disorder: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study.
    Am J Psychiatry 2023;180:241-251.

  4. Affengruber L, Wagner G, Dobrescu A, Toromanova A, et al.
    Values and Preferences of Patients With Depressive Disorders Regarding Pharmacologic and Nonpharmacologic Treatments : A Rapid Review.
    Ann Intern Med 2023;176:217-223.

  5. Omar Ahmad S, Longhurst J, Stiles D, Downard L, et al.
    A meta-analysis of exercise intervention and the effect on Parkinson's Disease Symptoms.
    Neurosci Lett 2023.

  1. Cohen JM, Alvestad S, Cesta CE, Bjork MH, et al.
    Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations.
    Ann Neurol 2023;93:551-562.

  2. Jin L, Nawaz H, Ono K, Nowell J, et al.
    One Minute of EEG Data Provides Sufficient and Reliable Data for Identifying Lewy Body Dementia.
    Alzheimer Dis Assoc Disord 2023;37:66-72.

  3. Gobron B, Couchot M, Irwin N, Legrand E, et al.
    Development of a first-in-class unimolecular dual GIP/GLP-2 analogue, GL-0001, for the treatment of bone fragility.
    J Bone Miner Res 2023.

  4. van Duin IAJ, Elias SG, van den Eertwegh AJM, de Groot JWB, et al.
    Time interval from primary melanoma to first distant recurrence in relation to patient outcomes in advanced melanoma.
    Int J Cancer 2023.

  5. Tolaney SM, Tarantino P, Graham N, Tayob N, et al.
    Adjuvant paclitaxel and trastuzumab for node-negative, HER2-positive breast cancer: final 10-year analysis of the open-label, single-arm, phase 2 APT trial.
    Lancet Oncol 2023;24:273-285.


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