Amedeo's Top 20

Amedeo Smart

Independent Medical Education

28 November 2022

Multidisciplinary Journal Club

  1. Bistervels IM, Buchmuller A, Wiegers HMG, Ni Ainle F, et al.
    Intermediate-dose versus low-dose low-molecular-weight heparin in pregnant and post-partum women with a history of venous thromboembolism (Highlow study): an open-label, multicentre, randomised, controlled trial.
    Lancet 2022.

  1. Goodall RL, Meredith SK, Nunn AJ, Bayissa A, et al.
    Evaluation of two short standardised regimens for the treatment of rifampicin-resistant tuberculosis (STREAM stage 2): an open-label, multicentre, randomised, non-inferiority trial.
    Lancet 2022.

  2. Harrington C, Krishnan S, Mack CL, Cravedi P, et al.
    Non-Invasive Biomarkers for the Diagnosis and Management of Autoimmune Hepatitis.
    Hepatology 2022.

  3. Bartels SAL, Donker M, Poncet C, Sauve N, et al.
    Radiotherapy or Surgery of the Axilla After a Positive Sentinel Node in Breast Cancer: 10-Year Results of the Randomized Controlled EORTC 10981-22023 AMAROS Trial.
    J Clin Oncol 2022.

  4. Hillmen P, Eichhorst B, Brown JR, Lamanna N, et al.
    Zanubrutinib Versus Ibrutinib in Relapsed/Refractory Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma: Interim Analysis of a Randomized Phase III Trial.
    J Clin Oncol 2022.

  1. Hodgson CL, Bailey M, Bellomo R, Brickell K, et al.
    Early Active Mobilization during Mechanical Ventilation in the ICU.
    N Engl J Med 2022;387:1747-1758.

  2. Semler MW, Casey JD, Lloyd BD, Hastings PG, et al.
    Oxygen-Saturation Targets for Critically Ill Adults Receiving Mechanical Ventilation.
    N Engl J Med 2022;387:1759-1769.

  3. Teitelbaum D, Elligsen M, Katz K, Lam PW, et al.
    Introducing the Escalation Antibiogram: A Simple Tool to Inform Changes in Empiric Antimicrobials in the Nonresponding Patient.
    Clin Infect Dis 2022;75:1763-1771.

  4. Bouffet E, Geoerger B, Moertel C, Whitlock JA, et al.
    Efficacy and Safety of Trametinib Monotherapy or in Combination With Dabrafenib in Pediatric BRAF V600-Mutant Low-Grade Glioma.
    J Clin Oncol 2022.

  5. Tran PT, Lowe K, Tsai HL, Song DY, et al.
    Phase II Randomized Study of Salvage Radiation Therapy Plus Enzalutamide or Placebo for High-Risk Prostate-Specific Antigen Recurrent Prostate Cancer After Radical Prostatectomy: The SALV-ENZA Trial.
    J Clin Oncol 2022.

  1. Yang JT, Wijetunga NA, Pentsova E, Wolden S, et al.
    Randomized Phase II Trial of Proton Craniospinal Irradiation Versus Photon Involved-Field Radiotherapy for Patients With Solid Tumor Leptomeningeal Metastasis.
    J Clin Oncol 2022;40:3858-3867.

  2. von Falkenhausen AS, Feil K, Sinner MF, Schonecker S, et al.
    Atrial Fibrillation Risk Assessment after Embolic Stroke of Undetermined Source.
    Ann Neurol 2022.

  3. Jezerskyte E, Mertens AC, Dieren SV, Eshuis WJ, et al.
    Gastrectomy Versus Esophagectomy for Gastroesophageal Junction Tumors: Short- and Long-Term Outcomes From the Dutch Upper Gastrointestinal Cancer Audit.
    Ann Surg 2022;276:e735-e743.

  4. Bakris GL, Ruilope LM, Anker SD, Filippatos G, et al.
    Analysis from the FIDELITY study examined finerenone use and kidney outcomes in patients with chronic kidney disease and type 2 diabetes.
    Kidney Int 2022.

  5. Zheng Q, Wang Y, Yang H, Sun L, et al.
    Cardiac and Kidney Adverse Effects of HIF Prolyl-Hydroxylase Inhibitors for Anemia in Patients With CKD Not Receiving Dialysis: A Systematic Review and Meta-analysis.
    Am J Kidney Dis 2022.

  1. Sheinboim D, Parikh S, Manich P, Markus I, et al.
    An Exercise-Induced Metabolic Shield in Distant Organs Blocks Cancer Progression and Metastatic Dissemination.
    Cancer Res 2022;82:4164-4178.

  2. Urva S, Coskun T, Loh MT, Du Y, et al.
    LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: a phase 1b, multicentre, double-blind, placebo-controlled, randomised, multiple-ascending dose trial.
    Lancet 2022.

  3. Niazi SK, Brennan E, Spaulding A, Crook J, et al.
    Impact of Recipient Age at Liver Transplant on Long-term Outcomes.
    Transplantation 2022.

  4. Kilgore LJ, Yi M, Bevers T, Coyne R, et al.
    Risk of Breast Cancer in Selected Women With Atypical Ductal Hyperplasia Who do not Undergo Surgical Excision.
    Ann Surg 2022;276:e932-e936.

  5. Wu Z, Yao T, Wang Z, Liu B, et al.
    Association between angiotensin-converting enzyme inhibitors and the risk of lung cancer: a systematic review and meta-analysis.
    Br J Cancer 2022.


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