Amedeo's Top 20

Amedeo Smart

Independent Medical Education

04 October 2021

Multidisciplinary Journal Club

  1. Cluver CA, Hiscock R, Decloedt EH, Hall DR, et al.
    Use of metformin to prolong gestation in preterm pre-eclampsia: randomised, double blind, placebo controlled trial.
    BMJ 2021;374:n2103.

  1. Li BT, Smit EF, Goto Y, Nakagawa K, et al.
    Trastuzumab Deruxtecan in HER2-Mutant Non-Small-Cell Lung Cancer.
    N Engl J Med 2021.

  2. Kim BW.
    Does Radioactive Iodine Therapy for Hyperthyroidism Cause Cancer?
    J Clin Endocrinol Metab 2021.

  3. Zhong WZ, Wang Q, Mao WM, Xu ST, et al.
    Gefitinib Versus Vinorelbine Plus Cisplatin as Adjuvant Treatment for Stage II-IIIA (N1-N2) EGFR-Mutant NSCLC: Final Overall Survival Analysis of CTONG1104 Phase III Trial.
    J Clin Oncol 2021;39:713-722.

  4. Boyle PA, Wang T, Yu L, Wilson RS, et al.
    To what degree is late life cognitive decline driven by age-related neuropathologies?
    Brain 2021;144:2166-2175.

  1. Howatt M, Klompas M, Kalil AC, Metersky ML, et al.
    Carbapenem Antibiotics for the Empiric Treatment of Nosocomial Pneumonia: A Systematic Review and Meta-analysis.
    Chest 2021;159:1041-1054.

  2. Burnham TS, May HT, Bair TL, Anderson JA, et al.
    Long-term Outcomes in Patients Treated with Flecainide for Atrial Fibrillation with Stable Coronary Artery Disease.
    Am Heart J 2021.

  3. Schmidt F, Weisblum Y, Rutkowska M, Poston D, et al.
    High genetic barrier to SARS-CoV-2 polyclonal neutralizing antibody escape.
    Nature 2021.

  4. Walsh J, Tozer DJ, Sari H, Hong YT, et al.
    Microglial activation and blood-brain barrier permeability in cerebral small vessel disease.
    Brain 2021;144:1361-1371.

  5. Bostrom P, Hultberg DK, Haggstrom J, Haapamaki MM, et al.
    Oncological Impact of High Vascular Tie After Surgery for Rectal Cancer: A Nationwide Cohort Study.
    Ann Surg 2021;274:e236-e244.

  1. Heerspink HJ, Cherney D, Postmus D, Stefansson BV, et al.
    A pre-specified analysis of the Dapagliflozin and Prevention of Adverse Outcomes in Chronic Kidney Disease (DAPA-CKD) randomized controlled trial on the incidence of abrupt declines in kidney function.
    Kidney Int 2021.

  2. Ryu WS, Schellingerhout D, Hong KS, Jeong SW, et al.
    Relation of Pre-stroke Aspirin Use With Cerebral Infarct Volume and Functional Outcomes.
    Ann Neurol 2021.

  3. Matar E, White SR, Taylor JP, Thomas A, et al.
    Progression of Clinical Features in Lewy Body Dementia Can Be Detected Over 6 Months.
    Neurology 2021;97:e1031-e1040.

  4. Cresswell FV, Meya DB, Kagimu E, Grint D, et al.
    High-dose oral and intravenous rifampicin for the treatment of tuberculous meningitis in predominantly HIV-positive Ugandan adults: a phase II open-label randomised controlled trial.
    Clin Infect Dis 2021.

  5. Lyon AR, Citro R, Schneider B, Morel O, et al.
    Pathophysiology of Takotsubo Syndrome: JACC State-of-the-Art Review.
    J Am Coll Cardiol 2021;77:902-921.

  1. Stanyer EC, Creeney H, Nesbitt AD, Robert Holland PR, et al.
    Subjective Sleep Quality and Sleep Architecture in Patients With Migraine: A Meta-analysis.
    Neurology 2021.

  2. Sestak I, Blake G, Patel R, Cuzick J, et al.
    Off-treatment bone mineral density changes in postmenopausal women receiving anastrozole for 5 years: 7-year results from the IBIS-II prevention trial.
    Br J Cancer 2021.

  3. Su G, Saglimbene V, Wong G, Natale P, et al.
    Healthy Lifestyle and Mortality Among Adults Receiving Hemodialysis: The DIET-HD Study.
    Am J Kidney Dis 2021.

  4. Del Mastro L, Mansutti M, Bisagni G, Ponzone R, et al.
    Extended therapy with letrozole as adjuvant treatment of postmenopausal patients with early-stage breast cancer: a multicentre, open-label, randomised, phase 3 trial.
    Lancet Oncol 2021.

  5. Chierigo F, Wenzel M, Wurnschimmel C, Flammia RS, et al.
    Survival after Radical Prostatectomy vs. Radiation Therapy in High-Risk and Very High-Risk Prostate Cancer.
    J Urol 2021.


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