Amedeo's Top 20

Amedeo Smart

Independent Medical Education


26 April 2021

Multidisciplinary Journal Club

  1. Bloem BR, Okun MS, Klein C.
    Parkinson's disease.
    Lancet 2021.

  1. Marson A, Burnside G, Appleton R, Smith D, et al.
    The SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled t
    Lancet 2021;397:1375-1386.

  2. Walter KS, Martinez L, Arakaki-Sanchez D, Sequera VG, et al.
    The escalating tuberculosis crisis in central and South American prisons.
    Lancet 2021.

  3. Marson A, Burnside G, Appleton R, Smith D, et al.
    The SANAD II study of the effectiveness and cost-effectiveness of levetiracetam, zonisamide, or lamotrigine for newly diagnosed focal epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial.
    Lancet 2021;397:1363-1374.

  4. Rokkas T, Gisbert JP, Malfertheiner P, Niv Y, et al.
    Comparative Effectiveness of Multiple Different First-Line Treatment Regimens for Helicobacter pylori Infection: a Network Meta-Analysis.
    Gastroenterology 2021.

  1. Lau JSY, McMahon JH, Gubser C, Solomon A, et al.
    The impact of immune checkpoint therapy on the latent reservoir in HIV infected individuals with cancer on antiretroviral therapy.
    AIDS 2021.

  2. Rusz J, Hlavnicka J, Novotny M, Tykalova T, et al.
    Speech biomarkers in rapid eye movement sleep behaviour disorder and Parkinson's disease.
    Ann Neurol 2021.

  3. Trivedi PJ, Crothers H, Mytton J, Bosch S, et al.
    Effects of Primary Sclerosing Cholangitis on Risks of Cancer and Death in People With Inflammatory Bowel Diseases, Based on Sex, Race, and Age.
    Gastroenterology 2020.

  4. Alva AS, Mangat PK, Garrett-Mayer E, Halabi S, et al.
    Pembrolizumab in Patients With Metastatic Breast Cancer With High Tumor Mutational Burden: Results From the Targeted Agent and Profiling Utilization Registry (TAPUR) Study.
    J Clin Oncol 2021.

  5. Pinto-Sanchez MI, Seiler CL, Santesso N, Alaedini A, et al.
    Association Between Inflammatory Bowel Diseases and Celiac Disease: A Systematic Review and Meta-Analysis.
    Gastroenterology 2020;159:884-903.e31.

  1. Lane NE, Saag K, O'Neill TJ, Manion M, et al.
    Real-world bone turnover marker use: impact on treatment decisions and fracture.
    Osteoporos Int 2020.

  2. Turpin W, Lee SH, Raygoza Garay JA, Madsen KL, et al.
    Increased Intestinal Permeability Is Associated With Later Development of Crohn's Disease.
    Gastroenterology 2020;159:2092-2100.e5.

  3. Lauterbach R, Bachar G, Ben-David C, Matanes E, et al.
    Association of Persistent Breech Presentation With External Cephalic Version Success.
    Obstet Gynecol 2021;137:258-262.

  4. Rentz DM, Papp KV, Mayblyum DV, Sanchez JS, et al.
    Association of Digital Clock Drawing with PET Amyloid and Tau Pathology in Normal Older Adults.
    Neurology 2021.

  5. Sadaghiani MS, Sheikhbahaei S, Werner RA, Pienta KJ, et al.
    A Systematic Review and Meta-analysis of the Effectiveness and Toxicities of Lutetium-177-labeled Prostate-specific Membrane Antigen-targeted Radioligand Therapy in Metastatic Castration-Resistant Prostate Cancer.
    Eur Urol 2021.

  1. Imperiale A, Meuter L, Pacak K, Taieb D, et al.
    Variants and Pitfalls of PET/CT in Neuroendocrine Tumors.
    Semin Nucl Med 2021.

  2. Orecchia R, Veronesi U, Maisonneuve P, Galimberti VE, et al.
    Intraoperative irradiation for early breast cancer (ELIOT): long-term recurrence and survival outcomes from a single-centre, randomised, phase 3 equivalence trial.
    Lancet Oncol 2021.

  3. Paone P, Cani PD.
    Mucus barrier, mucins and gut microbiota: the expected slimy partners?
    Gut 2020;69:2232-2243.

  4. Kennedy NA, Goodhand JR, Bewshea C, Nice R, et al.
    Anti-SARS-CoV-2 antibody responses are attenuated in patients with IBD treated with infliximab.
    Gut 2021;70:865-875.

  5. Altit G, Saeed S, Beltempo M, Claveau M, et al.
    Outcomes of Extremely Premature Infants Comparing Patent Ductus Arteriosus Management Approaches.
    J Pediatr 2021.


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