Amedeo's Top 20

Amedeo Smart

Independent Medical Education


29 March 2021

Multidisciplinary Journal Club

  1. Mintun MA, Lo AC, Duggan Evans C, Wessels AM, et al.
    Donanemab in Early Alzheimer's Disease.
    N Engl J Med 2021.

  1. Corey L, Gilbert PB, Juraska M, Montefiori DC, et al.
    Two Randomized Trials of Neutralizing Antibodies to Prevent HIV-1 Acquisition.
    N Engl J Med 2021;384:1003-1014.

  2. Mendelson SJ, Prabhakaran S.
    Diagnosis and Management of Transient Ischemic Attack and Acute Ischemic Stroke: A Review.
    JAMA 2021;325:1088-1098.

  3. Madhi SA, Baillie V, Cutland CL, Voysey M, et al.
    Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant.
    N Engl J Med 2021.

  4. Surial B, Mugglin C, Calmy A, Cavassini M, et al.
    Weight and Metabolic Changes After Switching From Tenofovir Disoproxil Fumarate to Tenofovir Alafenamide in People Living With HIV : A Cohort Study.
    Ann Intern Med 2021.

  1. Sadeghipour P, Talasaz AH, Rashidi F, Sharif-Kashani B, et al.
    Effect of Intermediate-Dose vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With COVID-19 Admitted to the Intensive Care Unit: The INSPIRATION R
    JAMA 2021.

  2. Cutrell AG, Schapiro JM, Perno CF, Kuritzkes DR, et al.
    Predictors of HIV-1 virologic failure to long-acting cabotegravir and rilpivirine: a multivariable analysis across three phase 3 studies.
    AIDS 2021.

  3. Zullo AR, Lee Y, Lary C, Daiello LA, et al.
    Comparative effectiveness of denosumab, teriparatide, and zoledronic acid among frail older adults: a retrospective cohort study.
    Osteoporos Int 2021;32:565-573.

  4. Kenmotsu H, Niho S, Tsuboi M, Wakabayashi M, et al.
    Randomized Phase III Study of Irinotecan Plus Cisplatin Versus Etoposide Plus Cisplatin for Completely Resected High-Grade Neuroendocrine Carcinoma of the Lung: JCOG1205/1206.
    J Clin Oncol 2020;38:4292-4301.

  5. McIntyre RS, Rosenblat JD, Nemeroff CB, Sanacora G, et al.
    Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation.
    Am J Psychiatry 2021.

  1. Takada K, Shimokawa M, Takamori S, Shimamatsu S, et al.
    Clinical impact of probiotics on the efficacy of anti-PD-1 monotherapy in patients with non-small cell lung cancer: A multicenter retrospective survival analysis study with inverse probability of treatment weighting.
    Int J Cancer 2021.

  2. Bates ER.
    In patients with CAD, adding colchicine to evidence-based therapies reduces MACE without increasing adverse outcomes.
    Ann Intern Med 2021;174:JC30.

  3. Bible KC, Kebebew E, Brierley J, Brito JP, et al.
    2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer.
    Thyroid 2021;31:337-386.

  4. Kang SH, Kim ME, Jang H, Kwon H, et al.
    Amyloid Positivity in Alzheimer/Subcortical-Vascular Spectrum.
    Neurology 2021.

  5. Ungaro RC, Brenner EJ, Gearry RB, Kaplan GG, et al.
    Effect of IBD medications on COVID-19 outcomes: results from an international registry.
    Gut 2021;70:725-732.

  1. Chammartin F, Lodi S, Logan R, Ryom L, et al.
    Risk for Non-AIDS-Defining and AIDS-Defining Cancer of Early Versus Delayed Initiation of Antiretroviral Therapy : A Multinational Prospective Cohort Study.
    Ann Intern Med 2021.

  2. Hetterich M, Gerken M, Ortmann O, Inwald EC, et al.
    Adjuvant chemotherapy for breast cancer patients with axillary lymph node micrometastases.
    Breast Cancer Res Treat 2021.

  3. Pellegrini D, Kawakami R, Guagliumi G, Sakamoto A, et al.
    Microthrombi as a Major Cause of Cardiac Injury in COVID-19: A Pathologic Study.
    Circulation 2021;143:1031-1042.

  4. Hanania AN, Paulino AC, Ludmir EB, Shah VS, et al.
    Early radiotherapy preserves vision in sporadic optic pathway glioma.
    Cancer 2021.

  5. Dasa O, Pepine CJ, Pearson TA.
    Aspirin in Primary Prevention: What Changed? A Critical Appraisal of Current Evidence.
    Am J Cardiol 2021;141:38-48.


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