Amedeo's Top 20

Amedeo Smart

Independent Medical Education


22 February 2021

Multidisciplinary Journal Club

  1. Page K, Melia MT, Veenhuis RT, Winter M, et al.
    Randomized Trial of a Vaccine Regimen to Prevent Chronic HCV Infection.
    N Engl J Med 2021;384:541-549.

  1. Wahl A, Gralinski LE, Johnson CE, Yao W, et al.
    SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801.
    Nature 2021.

  2. Packer DL, Piccini JP, Monahan KH, Al-Khalidi HR, et al.
    Ablation Versus Drug Therapy for Atrial Fibrillation in Heart Failure: Results from the CABANA Trial.
    Circulation 2021.

  3. Maertens JA, Rahav G, Lee DG, Ponce-de-Leon A, et al.
    Posaconazole versus voriconazole for primary treatment of invasive aspergillosis: a phase 3, randomised, controlled, non-inferiority trial.
    Lancet 2021;397:499-509.

  4. Wilding JPH, Batterham RL, Calanna S, Davies M, et al.
    Once-Weekly Semaglutide in Adults with Overweight or Obesity.
    N Engl J Med 2021.

  1. Albasri A, Hattle M, Koshiaris C, Dunnigan A, et al.
    Association between antihypertensive treatment and adverse events: systematic review and meta-analysis.
    BMJ 2021;372:n189.

  2. Nowakowski GS, Hong F, Scott DW, Macon WR, et al.
    Addition of Lenalidomide to R-CHOP Improves Outcomes in Newly Diagnosed Diffuse Large B-Cell Lymphoma in a Randomized Phase II US Intergroup Study ECOG-ACRIN E1412.
    J Clin Oncol 2021.

  3. Angiolillo DJ, Bhatt DL, Cannon CP, Eikelboom JW, et al.
    Antithrombotic Therapy in Patients With Atrial Fibrillation Treated With Oral Anticoagulation Undergoing Percutaneous Coronary Intervention: A North American Perspective: 2021 Update.
    Circulation 2021;143:583-596.

  4. Ducrocq G, Gonzalez-Juanatey JR, Puymirat E, Lemesle G, et al.
    Effect of a Restrictive vs Liberal Blood Transfusion Strategy on Major Cardiovascular Events Among Patients With Acute Myocardial Infarction and Anemia: The REALITY Randomized Clinical Trial.
    JAMA 2021;325:552-560.

  5. Park KW, Lee EJ, Lee JS, Jeong J, et al.
    Machine Learning Based Automatic Rating for Cardinal Symptoms of Parkinson.
    Neurology 2021.

  1. Fishbane S, El-Shahawy MA, Pecoits-Filho R, Van BP, et al.
    Roxadustat for Treating Anemia in Patients with CKD Not on Dialysis: Results from a Randomized Phase 3 Study.
    J Am Soc Nephrol 2021.

  2. Kuna ST, Reboussin DM, Strotmeyer ES, Millman RP, et al.
    Effects of Weight Loss on Obstructive Sleep Apnea Severity. Ten-Year Results of the Sleep AHEAD Study.
    Am J Respir Crit Care Med 2021;203:221-229.

  3. Gu C, Brereton N, Schweitzer A, Cotter M, et al.
    Metabolic Effects of Late Dinner in Healthy Volunteers-A Randomized Crossover Clinical Trial.
    J Clin Endocrinol Metab 2020;105.

  4. Wagner S, Merkling T, Metzger M, Bankir L, et al.
    Water intake and progression of chronic kidney disease: the CKD-REIN cohort study.
    Nephrol Dial Transplant 2021.

  5. Baumann T, Moia R, Gaidano G, Delgado J, et al.
    Lymphocyte doubling time in chronic lymphocytic leukemia modern era: a real-life study in 848 unselected patients.
    Leukemia 2021.

  1. Sehgal M, Ladabaum U, Mithal A, Singh H, et al.
    Colorectal Cancer Incidence after Colonoscopy at Ages 45-49 or 50-54 Years.
    Gastroenterology 2021.

  2. Longstreth GF.
    Internists' Misconceptions About PPIs: Increasing Knowledge and Implementing Guidelines.
    Am J Gastroenterol 2020;115:681-682.

  3. Smetana GW, Tetrault JM, Hill KP, Burns RB, et al.
    Should You Recommend Cannabinoids for This Patient With Painful Neuropathy? : Grand Rounds Discussion From Beth Israel Deaconess Medical Center.
    Ann Intern Med 2021.

  4. Minoshima S, Mosci K, Cross D, Thientunyakit T, et al.
    Brain [F-18]FDG PET for Clinical Dementia Workup: Differential Diagnosis of Alzheimer's Disease and Other Types of Dementing Disorders.
    Semin Nucl Med 2021.

  5. Kanemitsu Y, Shitara K, Mizusawa J, Hamaguchi T, et al.
    Primary Tumor Resection Plus Chemotherapy Versus Chemotherapy Alone for Colorectal Cancer Patients With Asymptomatic, Synchronous Unresectable Metastases (JCOG1007; iPACS): A Randomized Clinical Trial.
    J Clin Oncol 2021.


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