Amedeo's Top 20

Amedeo Smart

Independent Medical Education


09 March 2020

Multidisciplinary Journal Club

  1. Walsh M, Merkel PA, Peh CA, Szpirt WM, et al.
    Plasma Exchange and Glucocorticoids in Severe ANCA-Associated Vasculitis.
    N Engl J Med 2020;382:622-631.

  1. Fidler S, Stohr W, Pace M, Dorrell L, et al.
    Antiretroviral therapy alone versus antiretroviral therapy with a kick and kill approach, on measures of the HIV reservoir in participants with recent HIV infection (the RIVER trial): a phase 2, randomised trial.
    Lancet 2020.

  2. Schmid P, Cortes J, Pusztai L, McArthur H, et al.
    Pembrolizumab for Early Triple-Negative Breast Cancer.
    N Engl J Med 2020;382:810-821.

  3. Patnode CD, Perdue LA, Rossom RC, Rushkin MC, et al.
    Screening for Cognitive Impairment in Older Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
    JAMA 2020;323:764-785.

  4. Rosenkranz S, Howard LS, Gomberg-Maitland M, Hoeper MM, et al.
    Systemic Consequences of Pulmonary Hypertension and Right-Sided Heart Failure.
    Circulation 2020;141:678-693.

  1. Bernardi M, Angeli P, Claria J, Moreau R, et al.
    Albumin in decompensated cirrhosis: new concepts and perspectives.
    Gut 2020.

  2. Sandborn WJ, Ghosh S, Panes J, Schreiber S, et al.
    Efficacy of Upadacitinib in a Randomized Trial of Patients With Active Ulcerative Colitis.
    Gastroenterology 2020.

  3. Halim SA, Edwards FH, Dai D, Li Z, et al.
    Outcomes of Transcatheter Aortic Valve Replacement in Patients with Bicuspid Aortic Valve Disease: A Report from the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry.
    Circulation 2020.

  4. Hill MD, Goyal M, Menon BK, Nogueira RG, et al.
    Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial.
    Lancet 2020.

  5. Houillier C, Taillandier L, Dureau S, Lamy T, et al.
    Radiotherapy or Autologous Stem-Cell Transplantation for Primary CNS Lymphoma in Patients 60 Years of Age and Younger: Results of the Intergroup ANOCEF-GOELAMS Randomized Phase II PRECIS Study.
    J Clin Oncol 2019.

  1. Wilt TJ, Vo TN, Langsetmo L, Dahm P, et al.
    Radical Prostatectomy or Observation for Clinically Localized Prostate Cancer: Extended Follow-up of the Prostate Cancer Intervention Versus Observation Trial (PIVOT).
    Eur Urol 2020.

  2. McKay RR, Ye H, Xie W, Lis R, et al.
    Evaluation of Intense Androgen Deprivation Before Prostatectomy: A Randomized Phase II Trial of Enzalutamide and Leuprolide With or Without Abiraterone.
    J Clin Oncol 2019;37:923-931.

  3. Taranto-Montemurro L, Messineo L, Sands SA, Azarbarzin A, et al.
    The Combination of Atomoxetine and Oxybutynin Greatly Reduces Obstructive Sleep Apnea Severity. A Randomized, Placebo-controlled, Double-Blind Crossover Trial.
    Am J Respir Crit Care Med 2019;199:1267-1276.

  4. Yang X, Song H, Leslie G, Engel C, et al.
    Ovarian and breast cancer risks associated with pathogenic variants in RAD51C and RAD51D.
    J Natl Cancer Inst 2020.

  5. Lake JE, Wu K, Bares SH, Debroy P, et al.
    Risk Factors for Weight Gain Following Switch to Integrase Inhibitor-Based Antiretroviral Therapy.
    Clin Infect Dis 2020.

  1. Comstock CE, Gatsonis C, Newstead GM, Snyder BS, et al.
    Comparison of Abbreviated Breast MRI vs Digital Breast Tomosynthesis for Breast Cancer Detection Among Women With Dense Breasts Undergoing Screening.
    JAMA 2020;323:746-756.

  2. Kostis JB, Giakoumis M, Zinonos S, Cabrera J, et al.
    Meta-Analysis of Usefulness of Treatment of Hypercholesterolemia With Statins for Primary Prevention in Patients Older Than 75 Years.
    Am J Cardiol 2020.

  3. De Backer D, Cecconi M, Lipman J, Machado F, et al.
    Challenges in the management of septic shock: a narrative review.
    Intensive Care Med 2019;45:420-433.

  4. Barrionuevo P, Kapoor E, Asi N, Alahdab F, et al.
    Efficacy of Pharmacological Therapies for the Prevention of Fractures in Postmenopausal Women: A Network Meta-Analysis.
    J Clin Endocrinol Metab 2019;104:1623-1630.

  5. Zapotocky M, Beera K, Adamski J, Laperierre N, et al.
    Survival and functional outcomes of molecularly defined childhood posterior fossa ependymoma: Cure at a cost.
    Cancer 2019;125:1867-1876.


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