Amedeo's Top 20

Amedeo Smart

Independent Medical Education


24 June 2019

Multidisciplinary Journal Club

  1. Owens DK, Davidson KW, Krist AH, Barry MJ, et al.
    Preexposure Prophylaxis for the Prevention of HIV Infection: US Preventive Services Task Force Recommendation Statement.
    JAMA 2019;321:2203-2213.

  1. Gerstein HC, Colhoun HM, Dagenais GR, Diaz R, et al.
    Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial.
    Lancet 2019.

  2. Selph SS, Bougatsos C, Dana T, Grusing S, et al.
    Screening for HIV Infection in Pregnant Women: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
    JAMA 2019.

  3. Malik AA, Fuad J, Siddiqui S, Amanullah F, et al.
    TB Preventive Therapy for individuals exposed to drug-resistant tuberculosis: feasibility and safety of a community-based delivery of fluoroquinolone-containing preventive regimen.
    Clin Infect Dis 2019.

  4. Pivot X, Romieu G, Debled M, Pierga JY, et al.
    6 months versus 12 months of adjuvant trastuzumab in early breast cancer (PHARE): final analysis of a multicentre, open-label, phase 3 randomised trial.
    Lancet 2019.

  1. Earl HM, Hiller L, Vallier AL, Loi S, et al.
    6 versus 12 months of adjuvant trastuzumab for HER2-positive early breast cancer (PERSEPHONE): 4-year disease-free survival results of a randomised phase 3 non-inferiority trial.
    Lancet 2019.

  2. Chou R, Evans C, Hoverman A, Sun C, et al.
    Preexposure Prophylaxis for the Prevention of HIV Infection: Evidence Report and Systematic Review for the US Preventive Services Task Force.
    JAMA 2019;321:2214-2230.

  3. Owens DK, Davidson KW, Krist AH, Barry MJ, et al.
    Screening for HIV Infection: US Preventive Services Task Force Recommendation Statement.
    JAMA 2019.

  4. Wilson MR, Sample HA, Zorn KC, Arevalo S, et al.
    Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis.
    N Engl J Med 2019;380:2327-2340.

  5. Flippot R, Dalban C, Laguerre B, Borchiellini D, et al.
    Safety and Efficacy of Nivolumab in Brain Metastases From Renal Cell Carcinoma: Results of the GETUG-AFU 26 NIVOREN Multicenter Phase II Study.
    J Clin Oncol 2019.

  1. Dorner T, Furie R.
    Novel paradigms in systemic lupus erythematosus.
    Lancet 2019;393:2344-2358.

  2. Radford M, Parks DC, Ferrante S, Punekar Y, et al.
    Dolutegravir and lamivudine vs other antiviral regimens in HIV-1 treatment-naive patients: a systematic review and network meta-analysis.
    AIDS 2019.

  3. Leonenko G, Shoai M, Bellou E, Sims R, et al.
    Genetic risk for Alzheimer's disease is distinct from genetic risk for amyloid deposition.
    Ann Neurol 2019.

  4. Chou R, Dana T, Grusing S, Bougatsos C, et al.
    Screening for HIV Infection in Asymptomatic, Nonpregnant Adolescents and Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
    JAMA 2019.

  5. Zhong WZ, Chen KN, Chen C, Gu CD, et al.
    Erlotinib Versus Gemcitabine Plus Cisplatin as Neoadjuvant Treatment of Stage IIIA-N2 EGFR-Mutant Non-Small-Cell Lung Cancer (EMERGING-CTONG 1103): A Randomized Phase II Study.
    J Clin Oncol 2019.

  1. Herold KC, Bundy BN, Long SA, Bluestone JA, et al.
    An Anti-CD3 Antibody, Teplizumab, in Relatives at Risk for Type 1 Diabetes.
    N Engl J Med 2019.

  2. Bjellvi J, Olsson I, Malmgren K, Wilbe Ramsay K, et al.
    Epilepsy duration and seizure outcome in epilepsy surgery: A systematic review and meta-analysis.
    Neurology 2019.

  3. Murray PG, Young LS.
    An etiological role for the Epstein-Barr virus in the pathogenesis of classical Hodgkin lymphoma.
    Blood 2019.

  4. Durcan L, O'Dwyer T, Petri M.
    Management strategies and future directions for systemic lupus erythematosus in adults.
    Lancet 2019;393:2332-2343.

  5. Pratley R, Amod A, Hoff ST, Kadowaki T, et al.
    Oral semaglutide versus subcutaneous liraglutide and placebo in type 2 diabetes (PIONEER 4): a randomised, double-blind, phase 3a trial.
    Lancet 2019.


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