Amedeo's Top 20

Amedeo Smart

Independent Medical Education


25 February 2019

Multidisciplinary Journal Club

  1. Carrat F, Fontaine H, Dorival C, Simony M, et al.
    Clinical outcomes in patients with chronic hepatitis C after direct-acting antiviral treatment: a prospective cohort study.
    Lancet 2019.

  1. Pflug A, Lukarska M, Resa-Infante P, Reich S, et al.
    Structural insights into RNA synthesis by the influenza virus transcription-replication machine.
    Virus Res 2017.

  2. Jernberg T, Lindahl B, Alfredsson J, Berglund E, et al.
    Long-Term Effects of Oxygen Therapy on Death or Hospitalization for Heart Failure in Patients With Suspected Acute Myocardial Infarction
    Circulation 2018;138:2754-2762.

  3. Anderson CS, Huang Y, Lindley RI, Chen X, et al.
    Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial.
    Lancet 2019.

  4. Marrazzo JM, Rabe L, Kelly C, Richardson B, et al.
    Tenofovir gel for prevention of herpes simplex virus type-2 acquisition: findings from the VOICE Trial.
    J Infect Dis 2019.

  1. Hanley DF, Thompson RE, Rosenblum M, Yenokyan G, et al.
    Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint phase 3 trial.
    Lancet 2019.

  2. .
    Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): an ambulance-based, randomised, sham-controlled, blinded, phase 3 trial.
    Lancet 2019.

  3. Espay AJ, Vizcarra JA, Marsili L, Lang AE, et al.
    Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases.
    Neurology 2019;92:329-337.

  4. Intagliata NM, Caldwell SH, Tripodi A.
    Diagnosis, Development, and Treatment of Portal Vein Thrombosis in Patients With and Without Cirrhosis.
    Gastroenterology 2019.

  5. Lachmandas E, Eckold C, Bohme J, Koeken VACM, et al.
    Metformin alters human host responses to Mycobacterium tuberculosis in healthy subjects.
    J Infect Dis 2019.

  1. Jiang W, Wang S, Chen H, Ren H, et al.
    A bivalent heterologous DNA-virus-like particles prime-boost vaccine elicits broad protection against both groups 1 and 2 influenza A viruses.
    J Virol 2017.

  2. Coe IR, Wiley R, Bekker LG.
    Organisational best practices towards gender equality in science and medicine.
    Lancet 2019;393:587-593.

  3. Watts NB, Grbic JT, Binkley N, Papapoulos S, et al.
    Invasive Oral Procedures and Events in Women With Postmenopausal Osteoporosis Treated With Denosumab for up to 10 Years.
    J Clin Endocrinol Metab 2019.

  4. Wen W, Schwabe RF.
    Soluble fibers improve metabolic syndrome but may cause liver disease and hepatocellular carcinoma.
    Hepatology 2019.

  5. Jakimovski D, Weinstock-Guttman B, Gandhi S, Guan Y, et al.
    Dietary and lifestyle factors in multiple sclerosis progression: results from a 5-year longitudinal MRI study.
    J Neurol 2019.

  1. Borchmann S, Joffe E, Moskowitz CH, Zelenetz AD, et al.
    Active surveillance for nodular lymphocyte-predominant Hodgkin lymphoma.
    Blood 2019.

  2. Cook R, Lamont T, Martin R.
    Lifestyle changes may be more important than drugs for mild hypertension.
    BMJ 2019;364:l571.

  3. .
    Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer in 26 randomised trials.
    Lancet 2019.

  4. Dunlop BW, LoParo D, Kinkead B, Mletzko-Crowe T, et al.
    Benefits of Sequentially Adding Cognitive-Behavioral Therapy or Antidepressant Medication for Adults With Nonremitting Depression.
    Am J Psychiatry 2019.

  5. Peters MJ, Jones GAL, Wiley D, Wulff J, et al.
    Conservative versus liberal oxygenation targets in critically ill children: the randomised multiple-centre pilot Oxy-PICU trial.
    Intensive Care Med 2018;44:1240-1248.


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